international stocks trading in new york closed lower on tuesday the spbny mellon index of american depositary receipts fell 15 to 14845 the european index dived 16 to 14563 the asian index declined 13 to 16853 the latin american index dropped 23 to 18567 and the emerging markets index decreased 18 to 28149 adrs of numinus wellness on tuesday closed up 11 to 25 cents after the company said it is joining a large latestage international clinical study of mental health company compass pathways investigational psilocybin therapy for treatmentresistant depression adrs of heartbeam closed up 83 to 236 after the medical technology company said it signed a strategic alliance agreement with samsung