shares of avenue therapeutics inc which began trading friday on a reverse stock split adjusted basis were lower the shares opened at 615 rising as high as 635 before pulling back at 328 pm et the shares had fallen 38 to trade at 411 trading in the stock was paused several times on friday due to volatility on thursday the company said it would effect a 1for15 reverse split of its common stock the stock closed before the reverse split took place at 44 cents doubling its price on the day