international stocks trading in new york closed higher on wednesday the spbny mellon index of american depositary receipts ticked up 15 to 14296 the european index edged 16 higher to 13882 the asian index climbed 13 to 16488 the latin american index rose 12 to 18130 while the emergingmarkets index gained 16 to 27638 astrazeneca plc was among those whose adrs traded actively the pharmaceutical company edged up 03 after it said imfinzi has been approved in the european union for biliary tract cancer while lynparza in combination with abiraterone and prednisone or prednisolone has been approved in the eu for prostate cancer carnival plc gained 44 after it narrowed its loss in the fourth quarter and said it saw bookings accelerate after it further relaxed covid19 protocols early in the quarter with momentum ongoing into december