a logo on the sanofi exhibition space at the viva technology conference dedicated to innovation and startups at porte de versailles exhibition center in paris france june 15 2022 shares of sanofi and regeneron both jumped by more than 6 on thursday after the pharmaceutical companies released promising data showing their jointly developed asthma drug dupixent also shows promise in treating copd patients new data from a phase three clinical trial shows dupixent reduced bad bouts of chronic obstructive pulmonary disease or copd by 30 compared with a placebo over 52 weeks the drug is already approved for asthma and some skin conditions like eczema but it could become the first new treatment in over a decade for copd copd is a lifethreatening respiratory disease that causes progressive lung function decline with symptoms like persistent cough and breathlessness that can hinder an individuals ability to do daily activities it caused 32 million deaths globally in 2019 making it the third leading cause of death according to the world health organization smoking is a key risk factor for copd but individuals who quit smoking can also develop the disease the trial enrolled copd patients with type 2 inflammation – an allergic response that can result in decreased lung function roughly 300000 people in the us alone live with copd with type 2 inflammation according to regeneron the more than 900 participants in the trial were current or former smokers and those who received dupixent showed improvements in lung function quality of life and respiratory symptoms those results are a win for dupixent as competing copd drugs from drugmakers like astrazeneca and gsk struggle to make successful strides toward approval change cannot come quick enough for people living with uncontrolled copd but unfortunately many investigational treatments have failed to demonstrate significant clinical outcomes leaving these vulnerable patients with limited treatment options said dr dietmar berger sanofis chief medical officer in a company press release we are excited to share these unprecedented and potentially paradigmshifting clinical results which may give new hope to patients caregivers and physicians the companies said a second phase three trial of dupixent in copd is ongoing with data expected in 2024 this benefit suggests a clear clinically meaningful benefit for dupixent and should support broad usage for the asset in this segment of the copd market schott wrote in a research note to clients thursday he added that jp morgan expects to see new copd patients adding a 15 billion to 2 billion in new sales for dupixent dupixent raked in sales of 87 billion last year for regeneron which was a 40 increase from 2021 cowen analyst steve scala shared a similar take on the new data noting that copd represents a major market opportunity for the drug we expect solid uptake for dupixent once approved he wrote in a note thursday adding that we are strongly encouraged by positive data in copd which could become a blockbuster opportunity for dupixent and extend its growth trajectory through 2030