centene corp said friday that it would reduce its real estate footprint as part of a transition to a more modern flexible work environment the healthcare company is expecting to decrease its domestic leased space by 65 and log impairments of about 750 million to 800 million the estimated pretax costs will be recorded primarily during the second and third quarters of 2022 centene said it expects its leased real estate expense to be reduced by an annualized run rate of 180 million to 200 million