there is now considerable experience with issues related to the establishment of publicprivate partnerships in biomedical research and health innovation and efficiency and effectiveness lessons can be learned from existing partnerships concerned with alzheimer s disease professional management of partnerships is a prerequisite for the efficient use of limited resources and the generation of value out of collaborative efforts in order to leverage the full spectmm of advantages of publicprivate partnerships in alzheimer s disease the issues and needs ideologies and objectives of each individual stakeholder need to be addressed upfront