in addition to characterizing the state of the population for instance when performing the economic evaluations of cancer control interventions pohem typically uses a simulation sample size of one million individuals and draws together information on risk factors disease incidence by age gender and celltype stage distribution at the time of diagnosis and the standard or typical diagnostic and therapeutic approaches used moreover data on disease progression after initial diagnosis depending upon age gender and stage at diagnosis are required in addition to followup patterns of practice treatment at relapse and terminal care therefore different datasets are used which include various cancer registries and hospital registries data from pharmaceutical associations population health surveys screening studies and clinical trials etc