There could be interactions between your drug and certain liquids. Grapefruit juice, for example, has become notorious for inhibiting the effectiveness of several drugs, including lipitor, zocor, and allegra.
[header] How to swallow bitter medicine [title] Check with your pharmacist before mixing your medication. [step] The easiest way to take bitter liquid medicine is by mixing it with a better-tasting drink. This is usually fine with most medications, but you have to be careful.