Sexually active people who have only one partner in a monogamous relationship are safest, as long as neither partner has sex with anyone else. For some people, however, this might be unrealistic.
[header] How to prevent syphilis [title] Limit your number of sexual partners. [step] If you are sexually active, you can prevent syphilis by limiting your number of sexual partners. Your risk of contracting syphilis goes up with the number of sexual partners you have.