All of the following statement are true regarding silicosis, except:
Crystalline forms are much more fibrogenic Phagocytosed silica crystals activate the inflammasome, leading to the release of inflammatory mediators, paicularly IL-2 and TNF As the disease progresses, nodules coalesce into hard, collagenous scars Histologic examination reveals the hallmark lesion characterized by a central area of whorled collagen fibers with a more peripheral zone of dust-laden macrophages.