Which of the following statements about the fluoroquinolones is FALSE?
Gonococcal resistance to fluoroquinolones may involve changes in DNA gyrase Modification of fluoroquinolones dosage is required in patients if creatinine clearance is less than 50 mL/min A fluoroquinolone is the drug of choice for treatment of an uncomplicated urinary tract infection in a 7 year-old girl Fluoroquinolones inhibit relaxation of positively supercoiled DNA