An old lady came with complaint of pain in left calf region. A diagnosis of deep vein thrombosis (DVT) was made and she was put on warfarin therapy. After 3 months, she was brought to hospital with complaint of nose bleed which automatically stopped in few minutes. Her lab repos show INR of 7.0. To avoid hemorrhage, what to do next in addition to discontinuation of the drug?
Desmopressin Vitamin K1 Factor VIII Protamine sulfate