a female patient of age 53yrs is known case of osteoahritis & diabetic using METFORMIN 500mg , sitagliptin , glimipride 1mg since 10years. patient was recently diagnosed with CKD due to vigrous nsaid usage , now regarding her management what is the next step ?
Stop sitagliptin and sta linagliptin stop metaformin and change her to subcutaneous insulin nsaids are stoped and opiods are used for ahritis pain all of the above