A 21 year old male presented with sho stature & lack of secondary sexual characteristics. He has been operated for brain tumor 12 years ago & underwent cranial radiation. Which of the following is true regarding acquired hypopituitarism due to radiation?
At a dose of 50 Gy of radiation, only 5% of patients will manifest hypopituitarism. The majority of patients who develop hypopituitarism after cranial radiation, do so within a year of treatment. Growth hormone is the most common hormonal deficiency. Older adults are at highest risk from radiation-induced hypopituitarism.