A 54-year-old man presents with gnawing epigastric pain that occurs at regular intervals daily. The pain is paially relieved by antacids and food. Upper endoscopic studies reveal a duodenal lesion. Fuhermore, a biopsy confirms the benign nature of the lesion and demonstrates numerous Helicobacter pylori bacilli. Which of the following would be the most effective pharmacotherapy?
Aluminum or magnesium-containing antacid H2-receptor blocking agent Prostaglandin analog Proton pump inhibitor plus antibiotic