Steroid refractory ulcerative colitis is said to be present in a patients who have active disease despite:
Prednisolone up to 0.5 mg/kg/day over a period of 4 weeks Prednisolone up to 0.75 mg/kg/day over a period of 4 weeks Prednisolone up to 1 mg/kg/day over a period of 4 weeks Prednisolone up to 1.5 mg/kg/day over a period of 4 weeks