A patient on nitroprusside therapy developed cyanide toxicity. Sodium nitrite was administered i.v. to combat this poisoning. Beneficial effect of sodiumnitrite in this case is dependent on:
Direct chelation of cyanide with sodium nitrite Vasodilatation caused by sodium nitrite Conversion of hemoglobin to methemoglobin by sodium nitrite Facilitation of cyanocobalamin formation by sodium nitrite