• POC is available in a wide range of delivery systems.
• The dose of progestogen determines the mode of action and side effects.
• Irregular vaginal bleeding is a common reason for discontinuation of low-dose POC which do
• POC is available in a wide range of delivery systems.
• The dose of progestogen determines the mode of action and side effects.
• Irregular vaginal bleeding is a common reason for discontinuation of low-dose POC which do not inhibit ovarian activity completely.
• Despite normal ovarian activity the LNG-IUS is associated with amenorrhoea because of endometrial atrophy.
• Depo-Provera® inhibits ovarian activity completely and most users have amenorrhoea.
• There are few data on long-term safety. Theoretically POC are safer than CHC.
• POC does not increase the risk of cardiovascular disease.
• Depo-Provera® is associated with decreased BMD.
• Depo-Provera® may be associated with an increased risk of some sexually transmitted infections.
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