Environmental exposure to asbestos in the area around Goor has been established as the cause of pleural mesothelioma in women
Nederlands Tijdschrift Voor Geneeskunde. 2007 Nov 3;151(44):
Environmental exposure to asbestos in the area around Goor has been established as the cause of pleural mesothelioma in women
Nederlands Tijdschrift Voor Geneeskunde. 2007 Nov 3;151(44):2453-9. [Link]
Sinninghe DamstÃ© HE, Siesling S, Burdorf A.
Ziekenhuisgroep Twente, locatie Twenteborg Ziekenhuis, Afd. Longziekten, Almelo.
Objective: To determine whether a disease cluster of 22 additional cases of pleural mesothelioma among women could be attributed to environmental asbestos exposure due to asbestos fibers from waste material on roads and property yards. The women studied were observed in an area with substantial environmental exposure to asbestos during the period 1989-2002.
Design: Ecological study.
Method: In the study period of 1989-2002, all cases of mesothelioma among women, based on a strict histopathologic definition, occurring in the region of Twente, The Netherlands (n = 59) were provided by the regional cancer register. Additional information was collected on the occupational histories of the cases and their partners and addresses of residence through medical records, general practitioners, and next-of-kin. Environmental asbestos exposure was assigned to all cases that had had a long-term stay in a house in the area around Goor with demonstrated local environmental asbestos pollution and where any contact with asbestos through occupation or in the household had been excluded.
Results: In the risk area around Goor, out ofa total of 28 cases ofwomen with pleural mesothelioma, asbestos in the environment was found to be the only source of asbestos exposure for to women. In a further 4 women, environmental asbestos exposure was found to be the most likely cause of pleural mesothelioma. The average cumulative exposure was around 0.11 fiber/ml x exposure y