Δημοσίευση στις 2018/3/24 στο PubMed: https://www.ncbi.nlm.nih.gov/pubmed/29570514
Palatini P, Rosei EA, Avolio A, Bilo G,, Casiglia
Δημοσίευση στις 2018/3/24 στο PubMed: https://www.ncbi.nlm.nih.gov/pubmed/29570514
Palatini P, Rosei EA, Avolio A, Bilo G,, Casiglia E, Ghiadoni L, Giannattasio C, Grassi G, Jelakovich B, Julius S0, Mancia G, McEniery CM, O’Rourke MF, Parati G,, Pauletto P, Pucci G,, Saladini F, Strazzullo P, Tsioufis K, Wilkinson IB, Zanchetti A.
: Whether isolated systolic hypertension in the young (ISHY) implies a worse outcome and needs antihypertensive treatment is still a matter for dispute. ISHY is thought to have different mechanisms than systolic hypertension in the elderly. However, findings from previous studies have provided inconsistent results. From the analysis of the literature, two main lines of research and conceptualization have emerged. Simultaneous assessment of peripheral and central blood pressure led to the identification of a condition called pseudo or spurious hypertension, which was considered an innocent condition. However, an increase in pulse wave velocity has been found by some authors in about 20% of the individuals with ISHY. In addition, obesity and metabolic disturbances have often been documented to be associated with ISHY both in children and young adults. The first aspect to consider whenever evaluating a person with ISHY is the possible presence of white-coat hypertension, which has been frequently found in this condition. In addition, assessment of central blood pressure is useful for identifying ISHY patients whose central blood pressure is normal. ISHY is infrequently menti