polymer blend is desirable and manipulation is difficult or limited. Instead, it would be highly advantageous to assign the separation to the system to reorganize itself. We would refer to bio/polymers under confinement [@claessens], nanodevice fabrication plus microfluidics and micro-encapsulation [@DeCock; @Watanabe; @Wang; @Seiffert] besides implications for chromosomes organization inside the nucleus of the cell [@Lanctot; @Jun15082006; @Cook21092009].

The nucleus of the eukaryotic cell is a good example of a crowded inhomogeneous system under geometrical confinement where besides many proteins and enzymes, there are two major states of chromatin; euchromatin and heterochromatin. Euchromatin represents a more flexible chain of nucleosomes which is an active gene-rich chromatin and heterochromatin is a dense stiff compaction of nucleosomes and considered as inactive gene-poor chromatin [@Gaspar]. Depending on the cell type, the diameter of the nucleus is around $2-10 \mu {\rm m}$, therefore, the volume fraction of the chromatin inside the nucleus varies between $2\%-30\%$ [@halverson; @Phillips]. If we compare our stiff segmented polymer model, Fig. \[fig:seg\_poly\](a), and the coarse-grained structures of euchromatin and heterochromatin [@Gaspar], we can draw a qualitative analogy between them where our segments represent the heterochromatin and the rest of the flexible parts represent the euchromatin. The volume fraction in 