experiment the same difficulties of the rest of systems as far as its interoperability is concerned. Connectivity problems arise due to incompatibility of the software level (e.g., operating system, networking protocols, format of exchanged data, etc.). This problem has been well identified by the community that develops and designs medical systems and a number of projects have appeared that are studing the way of solving interoperability problems and providing safe solutions at the same time. The distribution software typically takes care of these type of technical issues, so the middleware community has a lot to say in this picture. Solutions will have to consider ICE, that is the most popular and widely adopted standard for medical device interoperability. Most of its implementations are based on publish-subscribe middleware such as the Data Distribution System [@DDS]. Nevertheless, there is a long road towards obtaining proper solutions for efficient communication and interoperation in a timely, flexible, and reconfigurable manner.

On the author’s road to provide one of this solutions, this paper performs a study of a reduced set of solutions in the research to design and develop real-time middleware. The paper analyzes the research on distribution software of his reference distributed real-time systems 