H&E & TR: \[3.7, 7.0\]; &H&E\
Characteristics & TE: \[122, 130\] & & TE: \[107\] &\
Number of Patients/Slices & 74/1994 & 74/478 & 16/430 & 16/65\
Matrix Size & $K,L\in[256,512]$ $M\in[24,43]$ & W,H $\in$ \[1663,7556\] & $K,L = 320$, $M \in [21,31]$ & W,H $\in$ \[2368,6324\]\
Pixel Spacing (mm) & $\in$ \[0.27,0.94\] & $\in$ {0.0081,0.0162} & $\in$ \[0.41,0.43\] & 0.0072\*\
Distance Between Slices (mm) & $\in$ \[3,5.2\] & Same as MRI via 3D printed mold & 4 & Free hand\
Annotations & Prostate, Anatomic Landmarks & Prostate, Anatomic Landmarks, Cancer & Prostate, Cancer, Urethra & Prostate, Urethra, Cancer\

Data Description {#data-description .unnumbered}
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Our IRB approved study includes $N_1=73$ subjects from Stanford Hospital (Cohort C1) and $N_2=16$ patients from the “Prostate Fused MRI Pathology” collection, The Cancer Imaging Archive [@madabhushi_fused_2016] (Cohort C2) ( \[tab:data\]). A subset of 15 subjects from cohort C1 was previously utilized in [@rusu_framework_2019]. The subjects in C1 had an MRI acquired between 2016-2019 prior to the radical prostatectomy, and the excised prostate was submitted for histologic preparation to generate whole-mount sections. [ The subjects in C2 (description available at <https://wiki.cancerimagingarchive.net/display/Public/Prostate+Fused-MRI-Pathology>), underwent radical prostatectomy and had the prostate sectioned in quadrants before being submitted for histology 