Alb.

It is interesting to observe that at short-times the surface concentration of Fib increases more than linearly with time. This is more evident at low $X_P$ (Fig. \[fdil300\]a). This behavior has been predicted in other models for single protein adsorption including conformational changes and has been noted that it is not reproduced by standard Langmuir kinetics [@Adamczyk1995]. It can be understood as a consequence of the ability of Fib to adsorb in both its “laying down” and “standing up” conformation that is not captured by standard Langmuir kinetics. This stage can be considered as the first step of Fib adsorption and occurs when the competitions with the other proteins is not strong, i.e. when the total surface concentration has not reached its saturation (Fig. \[fdil300\]d).

![Same data at $T=300$ K as in in Fig. \[f1\] now separated for (a) Fib, (b) IgG, (c) Alb, (d) and their sum at $X_P=100\%$ ($\Delta$), $X_P=50\%$ (), and $X_P=25\%$ (). The time-scales increase for decreasing $X_P$. In (a) the dashed lines are guide to the eyes for the linear regime of the three-steps kinetics of Fib adsorption. The vertical dotted lines are guides for the eyes to mark characteristic times. Note that the 