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abstract: 'Online social systems are multiplex in nature as multiple links may exist between the same two users across different social networks. In this work, we introduce a framework for studying links and interactions between users beyond the individual social network. Exploring the cross-section of two popular online platforms - Twitter and location-based social network Foursquare - we represent the two together as a composite *multilayer online social network*. Through this paradigm we study the interactions of pairs of users differentiating between those with links on one or both networks. We find that users with multiplex links, who are connected on both networks, interact more and have greater neighbourhood overlap on both platforms, in comparison with pairs who are connected on just one of the social networks. In particular, the most frequented locations of users are considerably closer, and similarity is considerably greater among multiplex links. We present a number of structural and interaction features, such as the multilayer Adamic/Adar coefficient, which are based on the extension of the concept of the node neighbourhood beyond the single network. Our evaluation, which aims to shed light on the implications of multiplexity for the link generation process, shows that multilayer features, 