color scales or glyphs. Effectively communicating all this information without overwhelming the viewer is a problem that has been addressed by several authors in the past [@Ropinski2006; @Lawonn2014; @Behrendt2017; @Lichtenberg2017].

Stereoscopic rendering is one of the most effective methods to communicate depth and shape of 3D objects. However, it usually requires instrumentation of the user, and is thus not widely available for most of the domain experts. Another commonly used technique to improve depth perception is chromadepth color coding [@Richard1987; @Bailey1998]. While with this technique, the perceptual benefits can be exploited when viewing appropriately coded images without special glasses, the effect can be further supported by using diffraction grating glasses. This fact was also exploited by the pseudo-chromadepth technique, which uses a color scale composed of only two colors (blue and red) to effectively convey depth information [@Ropinski2006]. The authors could show, that the reduced number of colors significantly improved the depth perception as compared to chromadepth. While these approaches work well when communicating vessel structures, they do not allow for the communication of additional information, since they exploit the color channel to encode depth information. Thus, various approaches have been considered to overcome this problem. Behrendt et al. [@Behrendt2017] 