has a *Paratope* ($Pt$) which aids in recognizing an *Epitope* ($Ep$) of the antigen ($Ag$). The extent of the complementarity or the affinity ($\psi$) in the *shapes* of $Ep$ and $Pt$ contributes to a recognition. Greater the value of $\psi$, greater is the potential of that $Ab$ to curb the corresponding $Ag$. An $Ab$ is selected for an $Ag$ only if the complementary shape of the $Ep$ of that $Ag$ lies within a small region of the shape space surrounding that of the $Pt$ of $Ab$. This small region which we refer to as the *Active Region (AR)*, is characterized by the *cross-reactivity threshold* ($\epsilon$) [@de2002artificial]. All antibodies within this region are attracted towards the antigen $Ag$ and hence are *stimulated* by it. Stimulated antibodies clone and proliferate proportionate to their affinities [@burnet1959clonal] and thus quell the antigenic attack. Fig. \[fig:shapeSpace\] shows a 2-D shape space $\mathcal{S}$ wherein the black dots signify antibodies and the crosses indicate the antigens. When a newly detected antigen has no antibodies to suppress it, an $Ab$ which is complementarily coincident to the $Ag$ is created (Fig. \[fig:shapeSpace\](a)). All $Ag$s that fall within the active region of this $Ab$ can now be catered to, by 