Jane and Jake attend their son Luke's graduation from college in New York City. After a dinner together, the two begin an affair, which continues in Santa Barbara. Jane is torn about the affair; Jake is not. While Agness has Jake scheduled for regular sessions at a fertility clinic, Jake is secretly taking medication, a side effect of which reduces his sperm count. After one of his sessions he has a lunchtime rendezvous with Jane at a hotel. Jake collapses in the hotel room and a doctor is called. The doctor speculates that the reason for Jake's distress may be the medication and says he should stop taking it. Jake and Jane's children know nothing of the affair, but Harley (John Krasinski), who is engaged to their daughter Lauren, spots the pair and the doctor in the hotel, but keeps silent.