Most runs scored in a game (since 1900):\n\nOne team: 29. (tie) Boston Red Sox vs. St. Louis Browns, June 8, 1950\nChicago White Sox vs. Oakland A's, April 23, 1955\n\nTwo teams: 49. Chicago Cubs beat the Philadelphia Phillies, 26–23 on Aug. 25, 1922, at Wrigley Field (then Cubs Park) in Chicago.