### SLC25A35 Gene Overview

**Gene Symbol**: SLC25A35  
**Protein Summary**: SLC25A35 is a member of the mitochondrial carrier family and is involved in the transport of various metabolites across the mitochondrial membrane.

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### 1. Associated Genes
The SLC25A35 gene can be associated with several other genes, particularly those involved in metabolic pathways and mitochondrial functions. Specific associations may include:

- **SLC25A20**: Another member of the SLC family involved in fatty acid transport.
- **SLC25A30**: Also related to mitochondrial transport and metabolism.
- **SLC25A22**: Known for its role in the transport of aspartate into the mitochondria.
- **SLC25A21**: Primarily involved in the transport of ADP/ATP across the mitochondrial membrane.

These genes can be connected through metabolic pathways that are crucial for mitochondrial function and energy metabolism.

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### 2. Aging and Age-Related Diseases
Though specific studies focusing exclusively on SLC25A35 in aging or age-related diseases are limited, alterations in mitochondrial function are widely recognized to play a role in aging and diseases such as:

- **Alzheimer's Disease**: Mitochondrial dysfunction is implicated in neurodegenerative conditions.
- **Cardiovascular Diseases**: Changes in mitochondrial transport proteins influence cardiac health, potentially linking SLC25A35 to heart-related age-related conditions.
- **Metabolic Disorders**: Given the gene's involvement in mitochondrial metabolism, it may be connected to age-related metabolic syndrome.

Studies examining mitochondrial carriers often highlight their roles in aging due to their impact on ATP production, reactive oxygen species (ROS) generation, and cellular signaling.

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### 3. Drug Interactions
At present, direct drug interactions specific to SLC25A35 are not well-documented in available pharmacological databases. However, broad classes of drugs that target mitochondrial pathways include:

- **Mitochondrial Protectants**: Compounds like MitoQ, which target mitochondrial oxidative stress.
- **Metabolic Modulators**: Drugs that influence energy metabolism may indirectly affect SLC25A35 function.
- **Insulin Sensitizers**: Drugs like metformin, which impact mitochondrial metabolism.

Continued research may uncover specific interactions and therapeutic implications involving SLC25A35.

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### 4. Pathways and Biological Processes
SLC25A35 is involved in several critical biological pathways, primarily related to mitochondrial functions, including:

- **Metabolic Pathways**: Involved in the transport of metabolites necessary for energy production, including the transport of intermediates of the tricarboxylic acid (TCA) cycle.
- **Amino Acid Metabolism**: May play a role in the transport of specific amino acids into the mitochondria for various biosynthetic processes or energy generation.
- **Oxidative Phosphorylation**: As part of the mitochondrial carrier family, it is likely involved in processes that underpin ATP synthesis coupled to electron transport.

Additional investigations into the SLC25A35 gene and its protein products could enhance understanding of both basic mitochondrial biology and its implications in health and disease.