### OR8D2 Gene Overview

**Gene Symbol:** OR8D2  
**Gene Type:** Olfactory receptor (GPCR family)  
**Function:** Involved in the perception of smell through interaction with odorant molecules, initiating a neuronal response via G-protein mediated signaling. 

#### 1. Associated Genes
The OR8D2 gene is part of the larger olfactory receptor gene family, which includes many other OR genes such as OR8D1, OR8D3, and OR8D4. While specific interactions with other genes are not commonly detailed, olfactory receptors are generally co-expressed or associated within the same family, and their expression can be influenced by various genetic factors or environmental conditions.

#### 2. Aging or Age-related Disease Association
Specific information about the OR8D2 gene in relation to aging or age-related diseases is not widely documented. However, olfactory function has been noted to decline with age, and reduced ability to perceive smells can be associated with neurodegenerative diseases such as Alzheimer’s or Parkinson’s disease. The potential non-functional alleles of the OR8D2 gene may contribute to varying olfactory sensitivity in different individuals as they age.

#### 3. Drug Interactions
Currently, there are no specific drugs or drug classes widely recognized to interact directly with OR8D2. However, since OR8D2 belongs to the GPCR family, potential implications exist for compounds targeting GPCRs broadly. Given this context, any future pharmacological research could explore drug interactions or modulation effects related to olfactory receptors.

#### 4. Pathways and Biological Processes
- **Olfactory signaling pathway:** OR8D2 is involved in the sensory perception of smell by recognizing and transducing odorant signals.
- **G-protein coupled receptor signaling pathway:** As a member of the GPCR family, it participates in the transduction of external signals into internal cellular responses.
- **Taste perception:** Although primarily related to smell, OR8D2 may also play a role in taste perception, as suggested in the summaries.

### Summary
The OR8D2 gene encodes an olfactory receptor essential for the perception of odorants. It is a member of the extensive olfactory receptor gene family, with variability in its function among individuals due to pseudogene status in some alleles. Research into its role in aging and disease is still evolving, with its primary function currently situated within the realm of sensory signaling pathways. Further investigations could shed light on potential therapeutic targets or its implications in age-related sensory decline.