### C2CD4C Gene Summary

**Gene Symbol:** C2CD4C  
**Predicted Location:** Cytosol  
**Protein Family:** C2CD4 family

The C2CD4C gene encodes a protein that belongs to the C2CD4 family, which is characterized by specific domains that are believed to be involved in multiple cellular processes, including the development and function of sensory cilia.

### 1. Genes Associated with C2CD4C

While direct associations can vary based on the biological context, C2CD4C may have relevant interactions with various genes involved in similar cellular processes, particularly those related to cilia formation and function. Genes that are often linked with ciliary function or similar pathways include:

- **C2CD4A**: A paralog of C2CD4C, sharing some functional characteristics and pathways.
- **IFT88**: Involved in the intraflagellar transport necessary for cilia assembly.
- **ARL13B**: Associated with cilia maintenance and function.
- **KIF3A**: Involved in kinesin motor activity important for ciliary transport.

### 2. Aging or Age-Related Disease Associations

There is limited direct evidence linking C2CD4C to aging or specific age-related diseases in humans, but given the role of cilia in various cellular processes—including signaling pathways related to development and maintenance—there are indirect associations suggesting that dysregulation of ciliary function may contribute to age-related degeneration. For instance, defects in ciliary function are linked to conditions such as:

- **Nephronophthisis**: A genetic disorder leading to kidney degeneration.
- **Ciliopathies**: A group of disorders (e.g., Bardet-Biedl syndrome) associated with ciliary dysfunction that may manifest symptoms related to aging features, such as obesity, renal failure, and retinal degeneration.

### 3. Drug Interactions

As of the latest information, no specific drugs or drug classes have been definitively reported to interact with C2CD4C. However, due to its role in cellular mechanisms related to cilia and potential involvement in disease processes, it may be relevant to ongoing research in targeted therapeutic approaches, particularly for ciliopathies. Future studies might shed light on pharmacological interactions.

### 4. Pathways and Biological Processes

C2CD4C is implicated in several important biological processes, primarily due to its role in cilia. Some known pathways and processes include:

- **Ciliary Assembly and Function**: The protein product is thought to play a role in the structure and functionality of cilia, which are essential for numerous signaling pathways and sensory functions in cells.
- **Developmental Processes**: Proper functioning of cilia is crucial during embryonic development, and mutants affecting ciliary proteins can lead to developmental defects.
- **Signal Transduction**: Cilia act as signaling centers for various pathways, including Hedgehog signaling, which is vital for cellular differentiation and growth.

Research is ongoing to elucidate the various roles of C2CD4C in different biological contexts, and broader connections to health and disease, which may reveal further functional implications.