### CFAP61 Gene Overview

**Gene Symbol:** CFAP61  
**Function:** CFAP61 (Cilia and Flagella Associated Protein 61) is predicted to play a crucial role in ciliary motility and assembly, specifically within the axoneme structure of motile cilia. Its putative function involves the regulation of ciliary movement through interaction with the radial spoke structure in cilia, which is essential for their proper function.

#### 1. Associated Genes
While the summary provided does not list specific genes, CFAP61 may interact with or be associated with other genes related to ciliary function. Some relevant associated genes include:

- **DNAH5**: Dynein axonemal heavy chain 5, an important component of the dynein complex, which is vital for ciliary movement.
- **RSPH9**: Radial spoke head protein 9, is involved in the assembly of the radial spoke and ciliary structure.
- **IFT complex proteins**: A variety of intraflagellar transport components (e.g., IFT88, IFT20), which contribute to ciliary assembly and maintenance.

#### 2. Aging and Age-Related Diseases
There is currently no direct and extensive literature linking CFAP61 specifically to aging or age-related diseases. However, since ciliary dysfunction is known to be implicated in various conditions such as ciliopathies (e.g., Primary Ciliary Dyskinesia) and possibly in aging-related processes, alterations or mutations in CFAP61 or its pathways may indirectly relate to age-associated cellular decline.

#### 3. Drugs and Drug Classes
As of the last available data, there are no specific drugs or drug classes widely recognized to directly interact with CFAP61. However, compounds targeting pathways involved in cilia function, such as those modulating ciliary signaling (like Hedgehog signaling pathway modulators), may indirectly influence CFAP61's effects in cellular contexts.

#### 4. Pathways and Biological Processes
CFAP61 is involved in several critical biological pathways associated with cilia:

- **Cilium Assembly and Organization**: CFAP61 is thought to play a role in the structural integrity and functioning of cilia, particularly in the assembly and maintenance of the axonemal architecture.
- **Ciliary Motility**: Due to its proposed involvement in the regulation of ciliary movement, it contributes to processes reliant on effective ciliary beating, such as fluid movement in the respiratory tract and sperm motility.
- **Intraflagellar Transport**: CFAP61 may also be involved in processes related to intraflagellar transport, critical for cilia assembly and maintenance.

In summary, CFAP61 is recognized for its involvement in ciliary motility regulation, and is likely associated with various other ciliary and flagellar assembly genes, though specific aging-related implications and drug interactions remain less defined and warrant further investigation.