### LINC00463 Gene Overview

**Gene Symbol**: LINC00463  
**Gene Type**: Long Intergenic Non-Protein Coding RNA  
**Location**: The LINC00463 gene is located on chromosome 8.

#### 1. Associated Genes
While specific associations may not always be emphasized in databases, LINC00463 is often investigated in relation to other genes involved in similar pathways or diseases, including:
- **TP53**: A tumor suppressor gene that may be regulated by non-coding RNAs.
- **MYC**: A transcription factor gene that is often related to cancer progression and may show interactions with non-coding RNAs.
- Other long non-coding RNAs that may be involved in similar regulatory networks.

#### 2. Relation to Aging and Age-Related Diseases
LINC00463 has been implicated in various age-related diseases, particularly in the context of:
- **Cancer**: Various studies suggest that alterations in long non-coding RNAs, including LINC00463, may play roles in tumorigenesis and cancer progression. Certain profiles of expression have been associated with poorer prognosis in specific cancers.
- **Neurodegenerative Diseases**: Some research indicates a potential link between non-coding RNAs and neurodegenerative disorders, though LINC00463 may not be as widely studied in this area compared to others.

Specific studies and results regarding age-related changes directly associated with LINC00463 are still needed for more detailed insights.

#### 3. Drug Interactions
Currently, there are no specific drugs or drug classes widely recognized to directly target or interact with LINC00463. However, the expression of non-coding RNAs can influence the efficacy of cancer therapies and other treatment modalities, suggesting that LINC00463 may play an indirect role in drug response, particularly in cancer treatment.

#### 4. Pathways and Biological Processes
LINC00463 is involved in various pathways and biological processes, including:
- **Gene Regulation**: Long non-coding RNAs generally regulate gene expression through several mechanisms, including chromatin remodeling and transcriptional interference.
- **Cell Cycle Regulation**: Given its potential involvement in cancer-associated pathways, LINC00463 may contribute to processes affecting cell proliferation and apoptosis.
- **Response to Stress**: Some studies suggest that certain long non-coding RNAs respond to cellular stress, which can relate to aging and disease contexts.

Overall, while there is progress in understanding the functional roles of LINC00463, ongoing research is necessary to unravel its mechanisms, associations, and potential therapeutic implications in aging and disease contexts.