### LINC00364 Gene Overview

**Gene Symbol:** LINC00364

LINC00364 is a long intergenic non-coding RNA (lincRNA) gene located on chromosome 2. As a non-coding RNA, it is believed to play a regulatory role in various biological processes, despite not coding for a protein.

#### 1. Associated Genes
While specific details of associations can vary, LINC00364 has been implicated in various cellular pathways and might interact with several other genes. Some known genes that may exhibit associations through regulatory networks or co-expression include:

- **MET** (Mesenchymal-epithelial transition factor)
- **EGFR** (Epidermal growth factor receptor)
- **RAP2A** (Ras-related protein Rap-2a)

These associations often arise in the context of specific studies and may vary based on the cellular or environmental context.

#### 2. Aging and Age-Related Diseases
Research regarding LINC00364 in the context of aging or age-related diseases is still emerging. However, some studies suggest that lincRNAs play a crucial role in the regulation of gene expression pertinent to cellular senescence, stem cell maintenance, and age-related disorders. Specific links to diseases, including cancer or neurodegenerative conditions, may exist but require more conclusive evidence for LINC00364. Some studies may frame its involvement in regulating gene networks associated with longevity or age-related decline.

#### 3. Drug Interactions
Direct interactions between drugs and the LINC00364 gene are not extensively documented in publicly available databases. However, since lincRNAs can modulate the expression of protein-coding genes often targeted in therapeutic pathways, there may be indirect associations. Many lincRNAs influence pathways that are relevant to drug mechanisms, particularly in cancer therapeutics. Specific drug interactions, if identified, would likely come from studies examining their effects on associated pathways involving LINC00364.

#### 4. Pathways and Biological Processes
LINC00364 is implicated in various biological processes and pathways, including:

- **Gene Regulation**: As a lincRNA, it is hypothesized to modulate gene expression either through transcriptional mechanisms or by influencing chromatin structure.
- **Cell Proliferation**: Potential roles in regulating cell cycle and growth, often associated with oncogenic pathways.
- **Response to Cellular Stress**: This might involve mechanisms that activate stress response pathways, relevant in both aging and disease states.
- **Developmental Processes**: Similar lincRNAs are known to participate in embryonic development and differentiation processes.

Overall, while the specific functions and associations of LINC00364 continue to be elucidated, it is part of a growing body of research that underscores the significance of non-coding RNAs in cellular function, health, and disease. Future studies are expected to yield more insights into its specific roles in aging and disease conditions.