### SEPTIN10 Gene Overview

**Gene Symbol:** SEPTIN10  
**Location:** Chromosome 3 (3p26.3)  
**Protein:**
- Functions as a filament-forming cytoskeletal GTPase.
- Associated with the organization of the cytoskeleton and cell division (potentially involved in cytokinesis).
- Displays GTP-binding and GTPase activity and is localized in both the cytoplasm and nucleus.

### 1. Associated Genes

SEPTIN10 is part of a larger family of septin genes, and other members of this family may be functionally related or may form complexes with SEPTIN10. Some associated genes include:
- **SEPTIN1**
- **SEPTIN2**
- **SEPTIN3**
- **SEPTIN5**
- **SEPTIN7**
- **SEPTIN9** 
- **SEPTIN11**  
These genes generally share structural similarities and are known to play roles in processes like cytokinesis, cell motility, and the organization of various cytoskeletal structures.

### 2. Aging and Age-Related Diseases

Although specific studies on the relation of SEPTIN10 to aging are limited, its role in cytokinesis and cellular dynamics implies that dysregulation of SEPTIN10 could potentially be involved in age-related diseases:
- **Cancer:** Abnormalities in cell division are hallmark features in many cancers, and alterations in septin family proteins, including SEPTIN10, have been observed in various malignancies.
- **Neurodegenerative diseases:** Given the role of septins in maintaining cellular structures and dynamics, some studies suggest a potential involvement in neurodegenerative mechanisms, although more research is needed to establish direct connections.

### 3. Drug Interactions

As of my last update in October 2023, there are no specific drugs or drug classes definitively known to interact solely with the SEPTIN10 gene. However, given its involvement in cytoskeletal dynamics, drugs targeting cytoskeleton integrity (e.g., some chemotherapeutics, like taxanes which influence microtubule dynamics) may have indirect effects on the functioning or regulation of septins in general.

### 4. Pathways and Biological Processes

SEPTIN10 is involved in several key biological processes and pathways:
- **Cytokinesis:** Critical for cell division, where accurate partitioning of cellular content is essential to prevent aneuploidy.
- **Cell Cycle Regulation:** Interventions in the activities of septins can affect overall cell cycle progression.
- **Neurogenesis:** Septins have been implicated in neuronal morphology and synaptic function.
- **Vesicular Trafficking:** Septins can play a role in the organization of membrane dynamics, impacting exocytosis and endocytosis.

### Summary

In summary, the SEPTIN10 gene encodes a GTPase involved in cytoskeletal organization and cell division, with implications for various cellular processes and potential associations with pathological conditions. Further research is needed to elucidate its precise roles in aging and disease mechanisms, as well as interactions with therapeutic agents.