### GTSE1-DT Gene Overview

**Gene Symbol:** GTSE1-DT  
**Gene Type:** Long non-coding RNA (lncRNA)  
**Location:** The GTSE1-DT gene is located on chromosome 22.

### Description:
GTSE1-DT (GTSE1 Distant Transcript) primarily functions as a long non-coding RNA associated with the regulation of gene expression. It has been implicated in several cellular processes.

### 1. Associated Genes:
While specific gene interactions for GTSE1-DT may not be extensively documented, genes usually associated with the GTSE1 locus and related pathways include:
- **GTSE1**: The neighboring gene, which has a role in mitosis and cellular response to DNA damage.
- **CCNB1** (Cyclin B1): Involved in cell cycle regulation.
- **TP53**: Plays a significant role in the cellular response to stress and DNA damage.

### 2. Aging and Age-Related Diseases:
There is limited direct information available on the association of GTSE1-DT with aging and age-related diseases. However, lncRNAs are increasingly recognized for their roles in the regulation of gene expression in processes involved in cellular senescence, stress responses, and cancer. Sequence studies suggest that alterations in lncRNA expression can be relevant to the modulation of aging or contribute to age-related diseases such as cancer and neurodegenerative diseases.

### 3. Drug Interactions:
Currently, there is no established literature indicating direct drug interactions with the GTSE1-DT gene. However, as research evolves, lncRNA interactions may correlate with broader molecular targets implicated in cancer treatment or gene regulation.

### 4. Pathways and Biological Processes:
GTSE1-DT is involved in various cellular processes, particularly those that encompass:
- Cell Cycle Regulation: Interaction with proteins involved in the G2/M phase transition.
- DNA Damage Response: May play a role in how cells respond to genomic instability.
- Cellular Proliferation: Gene expression regulation during mitotic events.

**Key Biological Processes include:**
- **Cellular Response to Stress:** Participates in the mechanisms that cells use to cope with stressors that can impact aging.
- **Cell Cycle Regulation:** Facilitates communication within pathways that govern cell division and proliferation.

### Conclusion:
While GTSE1-DT remains an important long non-coding RNA potentially influencing gene regulation and cell cycle processes, its full functional implications, particularly related to aging and pharmacological interactions, are still subjects of investigation. Further research will be essential to elucidate its roles in health and disease.