### FAM78A Gene Overview

**Gene Symbol:** FAM78A  
**Location:** Chromosome 10, 10q24.2  
**Gene Type:** Protein-coding gene

**Protein Summary:** FAM78A belongs to the FAM78 family, which contains genes presumed to be involved in various cellular processes, although the specific function of FAM78A is not fully elucidated.

### 1. Associated Genes
FAM78A has been associated with several other genes, particularly in the context of gene expression networks and disease studies. Notable associated genes include:
- **FAM78B:** Another member of the FAM78 family, suggesting possible functional redundancy or interaction.
- **EXOSC10:** Involved in RNA processing and degradation.
- **SMARCA4:** A gene associated with chromatin remodeling, which may interact with the pathways that involve FAM78A.

### 2. Aging and Age-Related Diseases
While specific studies directly linking FAM78A to aging or age-related diseases are limited, it has been implicated in:
- **Cancer Research:** Alterations in the expression of FAM78A and its family members can demonstrate links to tumorigenesis in various cancers. Loss or modulation of FAM78A expression can be associated with malignant transformations and may influence the aging process in tissue.
- **Cellular Senescence:** Some transcriptomics studies have indicated a role for FAM78A in cellular responses to stress, which may be analogous to processes observed in aging cells.

### 3. Drug Interactions
Currently, there are no well-defined drugs or drug classes explicitly known to interact with FAM78A directly. However, given its potential role in cancer pathways, it may interact indirectly with anti-cancer therapies that target signaling pathways or cellular processes that involve changes in the expression levels of FAM78A.

### 4. Pathways and Biological Processes
FAM78A is potentially involved in several biological processes, particularly related to the following pathways:
- **RNA Processing:** Given its associations with other gene products involved in RNA metabolism.
- **Cell Proliferation:** As inferred from its links to cancer-related gene expression studies.
- **Cell Signaling:** May play a role in pathways involved in tumor suppression and other cellular response mechanisms.

Overall, while FAM78A is recognized as part of a gene family with implications in various cellular processes, extensive functional studies are needed to clarify its roles in aging and disease mechanisms, as well as any direct pharmacological interactions. Further research could provide insights into the therapeutic targeting of FAM78A in age-related conditions or cancers.