### HPRT1P3 Gene Overview

**Gene Symbol:** HPRT1P3  
**Type:** Pseudogene  

**Summary:**
HPRT1P3 is classified as a pseudogene related to the HPRT1 gene, which encodes the enzyme hypoxanthine-guanine phosphoribosyltransferase. Pseudogenes are genomic sequences that resemble functional genes but either lack the capability to encode proteins or have lost their original function over evolutionary time. HPRT1P3 is located on chromosome X and does not play a direct role in protein coding.

### Related Genes

1. **HPRT1**: The functional gene encoding the enzyme hypoxanthine-guanine phosphoribosyltransferase, active in purine metabolism.
2. **Other HPRT family members**: Any genes that are paralogs or related by evolutionary processes, but the specifics may vary as the exact relationships are generally less defined for pseudogenes.

### Aging and Age-Related Diseases

Currently, there is limited direct evidence linking HPRT1P3 to aging specifically, as pseudogenes have historically been less studied in the context of age-related diseases compared to functional genes. However, since HPRT1 (the active gene with which it is associated) is critical for purine metabolism, its dysfunction can lead to conditions such as Lesch-Nyhan syndrome, which may have indirect implications for cellular aging. Additional studies may be necessary to elucidate any connections HPRT1P3 might share with age-related conditions.

### Drug Interactions

By virtue of being a pseudogene, HPRT1P3 is not directly involved in drug interactions or pharmacological pathways. However, the functional counterpart HPRT1 is involved in the metabolism of certain drugs, particularly those that are purine analogs (such as mercaptopurine and thioguanine). Any pharmacological impact associated with HPRT1P3 would arise indirectly through its association with HPRT1.

### Pathways and Biological Processes

Although HPRT1P3 itself does not contribute directly to any biological pathways due to its pseudogene status, the following biological processes are associated with its functional homolog HPRT1:

1. **Purine Metabolism**: The synthesis and breakdown of purine nucleotides.
2. **Nucleotide Salvage Pathway**: Recycling purines to synthesize nucleotides.
3. **Cellular Proliferation**: Impacts cellular growth and division via nucleotide availability.

In summary, while HPRT1P3 itself does not have a prominent functional role, understanding its relationship with the HPRT1 gene can provide insights into its biological context, especially in purine metabolism. Further research is needed to clarify its implications for aging or disease association.