The KHDC3L gene, also known as KH domain containing 3 like, is involved in a variety of essential biological processes, particularly during oocyte development and various aspects of genome stability and repair. Here is a more comprehensive overview of the gene extending beyond the available summaries.

### 1. Associated Genes:
- **BLM (Bloom syndrome protein)**: Involved in DNA repair and the resolution of DNA replication stress.
- **TRIM25 (Tripartite Motif Containing 25)**: Functions in ubiquitination processes.
- **RAD51**: Plays a crucial role in homologous recombination and DNA double-strand break repair.
- **PARP1**: Involved in the cellular response to DNA damage.
- **AURKA (Aurora kinase A)**: Regulates mitotic functions and spindle assembly.
- **PLK1 (Polo-like kinase 1)**: Also essential for cell cycle progression and mitotic regulation.
- **MAD2L1 (MAD2 mitotic arrest deficiency 1-like 1)**: A key player in the spindle assembly checkpoint ensuring proper chromosome segregation.
- **RHOA**: A small GTPase involved in actin dynamics and cell signaling.

### 2. Aging and Age-Related Diseases:
While specific research directly tying the KHDC3L gene to aging or age-related diseases is limited, its roles in DNA repair and maintaining genomic stability suggest involvement in processes that influence aging:
- **Genomic Instability**: Impairments in DNA repair mechanisms, as affected by KHDC3L, can lead to genomic instability, a hallmark of aging and age-related diseases like cancer.
- **Neurogenesis**: Since KHDC3L is implicated in neurogenesis and neuronal differentiation, dysregulation in these processes may contribute to age-related cognitive decline and neurodegenerative diseases.

### 3. Drug Interactions:
As of the latest available data, there are no specific drugs or drug classes explicitly listed as interacting with the KHDC3L gene. However, given that KHDC3L plays a role in DNA repair and cellular response to damage, drugs targeting DNA repair pathways or agents used in cancer therapies may indirectly affect its activity.

### 4. Biological Processes and Pathways:
The KHDC3L gene is associated with numerous pathways and biological processes, including:
- **DNA Repair**: Involvement in homologous recombination and double-strand break repair pathways.
- **Cell Cycle Regulation**: Required for proper spindle assembly and mitotic checkpoint function.
- **Oocyte Maturation**: Specifically expressed during oocyte development, critical in regulating actin dynamics.
- **Embryogenesis**: Essential for processes maintaining euploidy and facilitating successful early embryonic cell divisions.
- **Neurogenesis**: Involved in promoting the differentiation of neural stem cells, impacting learning and memory functions.

The multifaceted roles of KHDC3L underscore its importance in both reproductive biology and genomic integrity, laying the groundwork for its potential implications in various biological and disease contexts. Further research into the gene's functions and interactions could provide deeper insights into its roles in health and disease.