### SNORD112 Gene Overview

**Gene Symbol:** SNORD112

**Description:** SNORD112, also known as small nucleolar RNA domain 112, is part of the C/D box small nucleolar RNA (snoRNA) family. It plays a significant role in the processing and modification of ribosomal RNA (rRNA) and other RNA molecules, contributing to the formation of small ribonucleoprotein particles essential for ribosome biogenesis.

### 1. Associated Genes
While specific associations may vary by research, SNORD112 has been implicated in broader genetic contexts, particularly with other snoRNA genes. It is often mentioned alongside genes in the same C/D box snoRNA class, such as:
- **SNORD115:** Also known as the domain 115 snoRNA involved in rRNA modification.
- Other neighboring snoRNA genes, such as SNORD113 and SNORD114.

### 2. Aging and Age-Related Diseases 
The role of SNORD112 and other snoRNAs has been observed in cellular processes impacted by aging. Some studies suggest potential links between abnormalities in snoRNA processing and various age-related diseases. For example:
- Dysregulated snoRNA expression is implicated in age-related neurodegenerative diseases, including Alzheimer’s disease.
- Alterations in rRNA methylation patterns due to snoRNA dysfunction may potentially contribute to age-associated declines in ribosome biogenesis efficiency.

While specific studies linking SNORD112 directly to aging or age-related diseases are limited, general snoRNA function in RNA processing makes it a candidate for further investigation in these contexts.

### 3. Drug Interactions 
As of my last knowledge update, there are no specific drugs or drug classes directly linked to the modulation of SNORD112 activity. However, since snoRNAs are involved in fundamental cellular processes, certain classes of drugs that affect RNA synthesis, ribosome function, or cell growth might indirectly influence SNORD112’s function. This includes compounds like:
- **RNA polymerase inhibitors:** Such as Actinomycin D, which might affect overall RNA synthesis and indirectly alter snoRNA levels.
- **Antineoplastic agents:** Certain cancer therapies that target ribosome biogenesis may have downstream effects on snoRNAs and their targets.

### 4. Biological Pathways and Processes
SNORD112 is involved in several critical biological processes, including:
- **Ribosome biogenesis:** It plays a role in the modification and maturation of rRNA, essential for ribosome assembly.
- **RNA processing:** Participation in the enzymatic processes that modify other RNA species, including small nuclear RNAs (snRNA) and various forms of non-coding RNAs.
- **Nucleotide methylation:** Contributes to RNA methylation, which is vital for the stabilization and functionality of ribosomal RNA.

Overall, while SNORD112 is primarily recognized for its role in rRNA biogenesis and modification, its implications in aging, disease, and broader interactions require further investigational studies to elucidate its full biological significance and potential therapeutic applications.