### RPL3L Gene Overview

**Gene Symbol**: RPL3L

**Function and Expression**:  
The RPL3L gene encodes a protein that is a member of the L3P family of ribosomal proteins. It shows sequence similarity to ribosomal protein L3 and is a component of the ribosomal large subunit specifically in striated muscle cells. Unlike many ribosomal proteins with widespread expression, RPL3L exhibits a tissue-specific expression pattern, being predominantly expressed in skeletal muscle and the heart. Its role in these tissues suggests its potential involvement in muscle function and development.

### Additional Associations

1. **Associated Genes**:  
   While specific genes directly associated with RPL3L may not be detailed in initial summaries, ribosomal proteins and related genes such as RPL3 (the paralog it replaces in muscle) may have both functional similarities and regulatory interactions. Other genes involved in muscle function or related to ribosome biogenesis may also show some association.

2. **Aging and Age-Related Diseases**:  
   There is limited specific information on RPL3L in the context of aging or age-related diseases. However, given its function in muscle and heart tissue, studies exploring muscle atrophy, sarcopenia (age-related loss of muscle mass) or cardiac dysfunction in aging populations may reveal relevant insights. Alterations in ribosomal function often correlate with aging processes, particularly in tissues subjected to ongoing cellular stress and repair, such as muscle.

3. **Drug Interactions**:  
   Currently, there is no extensive information about specific drugs or drug classes that interact directly with RPL3L. However, any therapeutic agents affecting muscle function, such as those used in the treatment of muscle degenerative diseases or heart failure, could potentially relate to the biological pathways in which RPL3L is involved. Further research would be needed to elucidate specific interactions.

4. **Pathways and Biological Processes**:  
   RPL3L is involved in several biological processes, including:
   - **Ribosome Biogenesis**: It plays a role as a structural component of the ribosome in striated muscle cells.
   - **Muscle Growth and Function**: The encoded protein has been shown to inhibit myotube growth and may regulate muscle function.
   - **Protein Translation**: As part of the ribosomal machinery, RPL3L is vital in the translation of mRNA into proteins, which is particularly important in tissues with high rates of protein synthesis such as skeletal muscle and heart.

### Summary

The RPL3L gene encodes a specialized ribosomal protein in muscle tissue that plays a critical role in protein synthesis relevant to muscle function. It has a unique expression profile, primarily in heart and skeletal muscle, and may have implications in aging and muscle-related pathology, though more research is needed to fully clarify its role in such contexts.