### DDX17 Gene Summary

**Gene Symbol:** DDX17  
**Location:** Chromosome 17  

### Other Genes Associated with DDX17
1. **DDX5:** Closely related and functionally interacts with DDX17, involved in pre-mRNA splicing and transcription regulation.
2. **NFAT5:** A transcription factor whose splicing is influenced by DDX17, particularly in promoting specific exon inclusion.
3. **GSK3B:** A kinase whose splicing and activity are modulated by DDX17, affecting steroid hormone response pathways.
4. **ESR1 (Estrogen Receptor 1):** DDX17 regulates transcription and splicing of genes related to estrogen signaling.
5. **TP53:** DDX17 interacts with TP53, influencing various transcriptional programs.
6. **MYC:** DDX17 plays a role in MYC regulation via microRNA processing.

### Aging or Age-Related Diseases Associations
While specific studies directly linking DDX17 with aging or age-related diseases are not extensively documented, its involvement in processes like transcription regulation and splicing suggests potential roles in cellular senescence and response to stress, both of which are critical in aging. Abnormal splicing and misregulation of key signaling pathways (e.g., in cancer) have been associated with age-related changes; thus, DDX17 could have indirect implications in age-related conditions like cancer and muscle degeneration.

### Known Drug Interactions
Currently, there are no specific drugs or drug classes identified that interact directly with the DDX17 protein. However, its involvement in processes like mRNA degradation and transcription regulation could make it a potential target for therapies aiming to modulate RNA processing or splicing in disease contexts, particularly cancer and viral infections.

### Pathways and Biological Processes Involved
1. **RNA Processing:** Involved in pre-mRNA splicing, ribosomal RNA processing, and microRNA processing.
2. **Transcription Regulation:** Functions as a coactivator or corepressor, affecting genes involved in vital processes like cell growth, differentiation, and stress responses.
3. **Cell Signaling Pathways:** Implicated in estrogen and testosterone signaling pathways, affecting hormone-responsive gene transcription.
4. **Immune Response:** Influences innate immunity, particularly in restricting viral infections like bunyaviruses.
5. **Embryogenesis and Differentiation:** Involved in pathways regulating myoblast differentiation and cellular transitions such as epithelial-to-mesenchymal transition.

### Conclusion
The DDX17 gene plays a multifaceted role in RNA processing and regulation, impacting cellular growth, differentiation, and the immune response. Its potential links to aging and disease, as evidenced by its interaction with critical regulatory pathways, highlight its importance in maintaining cellular homeostasis and responding to environmental changes. Further research may provide insights into its more nuanced roles in age-related diseases and potential therapeutic targeting.