### ANKRD36C Gene Overview

**Gene Symbol**: ANKRD36C  
**Protein Summary**: ANKRD36C belongs to the ankyrin repeat domain-containing protein family, specifically the ANKRD36 subgroup. These proteins typically contain tandem repeats of ankyrin motifs that are involved in protein-protein interactions, playing roles in various cellular processes.

### 1. Associated Genes

The ANKRD36C gene may exhibit interactions or associations with several other genes, particularly those involved in cellular signaling and pathways. Some of the genes that have been noted in association studies or genetic analyses include:

- **ANKRD36**: The ancestral member of the ANKRD36 family.
- **ANKRD36B**: Another paralog that might share overlapping functions or interactions.
- **TP53**: The tumor protein p53, known for its role in regulating the cell cycle and preventing cancer.
- **CDKN1A (p21)**: A cyclin-dependent kinase inhibitor, which is also regulated by p53.

### 2. Aging and Age-Related Diseases

While direct studies focusing exclusively on ANKRD36C in the context of aging are limited, there are a few points of interest:

- **Cancer**: Given its association with TP53 and CDKN1A, mutations or expressions variance in ANKRD36C may influence tumorigenesis and therefore be indirectly linked to age-related disorders, specifically cancers that typically increase in prevalence with age.
- **Cell Cycle Regulation**: As part of pathways governing cellular proliferation and apoptosis, ANKRD36C may play a role in cellular senescence and the aging process.
- **Metabolic Disorders**: Some studies have linked members of the ANKRD family with metabolic diseases, which are of growing concern in aging populations.

### 3. Drug Interactions

As of the latest data, specific drug interactions with the ANKRD36C gene or its protein product have not been established in commonly referenced databases. However, given its potential role in cancer and metabolic signaling pathways, further research could elucidate possible interactions with:

- **Chemotherapeutic agents**: Drugs targeting pathways associated with tumorigenesis.
- **Kinase inhibitors**: These may inadvertently affect pathways in which ANKRD36C is involved.

### 4. Pathways and Biological Processes

ANKRD36C is known to be involved in several biological processes, although specific pathways may not be explicitly defined in the literature. Some potential processes and pathways include:

- **Regulation of the Cell Cycle**: Particularly through interactions with CDKN1A and TP53, possibly influencing the cell's response to stress and DNA damage.
- **Signal Transduction**: Involved in pathways that mediate cellular responses to stress and proliferation signals.
- **Tumor Suppression**: Given its association with proteins involved in preventing cancer development.

In summary, while the ANKRD36C gene is characterized by its ankyrin-repeat motifs and potential roles in cellular regulation and signaling, ongoing research is needed to uncover its specific interactions, particularly in aging and disease states. Further investigations may reveal precise mechanisms and therapeutic implications for targeting this gene in relevant conditions.