### ANKRD63 Gene Summary

The **ANKRD63** gene (Ankyrin Repeat Domain 63) encodes a protein that is involved in various cellular processes. It is characterized by the presence of ankyrin repeat motifs, which are protein-protein interaction domains. ANKRD63 is expressed in different tissues and may play roles in cellular signaling and modulation of other proteins' activity.

#### 1. Associated Genes
ANKRD63 has been reported to interact with several other genes/proteins, including:
- **TP53**: The tumor suppressor protein, which is crucial for regulating the cell cycle and apoptosis.
- **BCL2**: Involved in the regulation of apoptosis (programmed cell death).
- **JUN**: A component of the AP-1 transcription complex, implicated in various cellular processes including differentiation, proliferation, and survival.
- **MYC**: An oncogene that plays a role in cell cycle progression, apoptosis, and cellular transformation.

#### 2. Aging or Age-related Disease Associations
While specific studies directly linking ANKRD63 to aging or age-related diseases are limited, its involvement in pathways regulating apoptosis and cell cycle may suggest potential roles in age-related processes. Dysregulation of apoptotic pathways is often associated with neurodegenerative diseases, cancers, and other age-related conditions. More specific studies are needed to elucidate its role in these contexts.

#### 3. Drug Interactions
Currently, there are no specific drugs or drug classes publicly documented that directly interact with the ANKRD63 gene or its encoded protein. However, given its protein-protein interactions, it may have downstream effects influenced by drugs targeting related signaling pathways or diseases (e.g., anticancer agents affecting cell cycle regulation).

#### 4. Pathways and Biological Processes
ANKRD63 is believed to be involved in several biological processes, including but not limited to:
- **Cellular Response to Stress**: Due to its interactions with proteins involved in stress response and apoptosis.
- **Regulation of Apoptosis**: Functions within pathways that mediate programmed cell death.
- **Transcription Regulation**: Associated with modifying transcriptional activities through interactions with transcription factors.

Additionally, ANKRD63 may be implicated in processes related to cell signaling, especially pathways affected by oncogenic signaling due to its interactions with oncogenes and tumor suppressors. 

Further research may provide a clearer understanding of its complete functional landscape, particularly in contexts pertaining to disease and aging.