### SNORA84 Gene Overview

**Gene Symbol:** SNORA84

**Function:** The SNORA84 gene encodes a small nucleolar RNA (snoRNA) involved in the modification and processing of ribosomal RNA (rRNA), playing a critical role in the assembly of ribosomes, the cellular machinery responsible for protein synthesis.

### 1. Associated Genes
While the NCBI and UniProt summaries may not detail specific gene associations, snoRNAs often function collaboratively with other snoRNAs and proteins. Some snoRNA-associated genes can include:

- **NOP56**: A nucleolar protein that often works with snoRNAs.
- **NOP58**: Similar to NOP56, it is another protein that associates with various snoRNA complexes.
- **RPL (Ribosomal Protein Genes)**: Many snoRNAs help modify rRNA, which is part of ribosomal protein synthesis.

These gene associations stem from the general function of snoRNAs in ribosome biogenesis and rRNA modification.

### 2. Aging and Age-Related Diseases
While specific research directly linking SNORA84 to aging or age-related diseases is limited, the broader category of snoRNAs has been implicated in cellular aging processes. Research suggests that changes in ribosome biogenesis and rRNA processing are crucial to age-related cellular function and may affect:

- **Cellular Aging**: Altered expression of snoRNAs can impact ribosome function, which is critical in addressing cellular stress often associated with aging.
- **Age-Related Diseases**: Dysregulation of ribosome synthesis has been explored in conditions like cancer and neurodegenerative diseases, potentially connecting SNORA84 with these pathways through its rRNA modification functions.

### 3. Drug Interactions
Currently, specific drugs or drug classes explicitly targeting the SNORA84 gene have not been documented. However, due to its role in ribosome function, compounds that influence ribosomal activity could theoretically impact its function. Examples include:

- **Antibiotics** (e.g., aminoglycosides, macrolides): These often target bacterial ribosomes but may have implications on eukaryotic ribosome assembly indirectly.
- **Drugs impacting cellular stress responses**: These could affect how snoRNA functions in various cellular contexts.

### 4. Pathways and Biological Processes
The SNORA84 gene is involved in several important biological pathways and processes, which include:

- **Ribosome Biogenesis**: SNORA84 plays a role in the modification and maturation of rRNA necessary for ribosomal subunit assembly.
- **rRNA Methylation**: As a snoRNA, it likely guides methylation of specific rRNA molecules, influencing ribosomal function and efficiency.
- **Cell Growth and Proliferation**: Proper ribosomal biogenesis is essential for overall cellular growth and protein synthesis, implicating SNORA84 in these fundamental biological processes.

### Conclusion
In summary, the SNORA84 gene is a critical component of the ribosomal RNA modification process, impacting ribosome assembly and thereby influencing various cellular functions. While specific associations with additional genes, aging, drug interactions, or detailed pathways are not extensively documented, its general role in ribosome biogenesis places it within broader biological contexts that certainly warrant further research.