### SNORD83A Gene Overview

**Gene Symbol**: SNORD83A  
**Gene Type**: Small nucleolar RNA (snoRNA)  
**Function**: SNORD83A is part of the C/D box family of snoRNAs, which primarily function in the modification of ribosomal RNA (rRNA) through methylation and pseudouridylation. This gene plays a role in the processing and modification of pre-rRNA, contributing to ribosome biogenesis.

### 1. Associated Genes
While the NCBI and UniProt summaries may provide limited associations, small nucleolar RNAs, including SNORD83A, are often found in clusters and may be associated with other snoRNA genes within the same locus. It may interact with genes involved in ribosome assembly and function, such as those encoding ribosomal proteins. Potentially relevant genes could include:

- **RPS genes** (Ribosomal Protein Genes): These genes encode proteins that are fundamental components of ribosomes which may be indirectly associated with SNORD83A through ribosome biogenesis.

### 2. Aging and Age-Related Diseases
There is currently limited direct evidence regarding the specific involvement of the SNORD83A gene in aging or age-related diseases. However, snoRNAs, in general, are involved in the regulation of ribosome function, which is essential for cellular homeostasis and the maintenance of protein synthesis as organisms age. Dysfunctional ribosome biogenesis has been implicated in various age-related diseases and conditions, such as:

- **Cancer**: Alterations in snoRNA expression can affect ribosome biogenesis and protein synthesis, potentially leading to tumorigenesis.
- **Neurodegenerative disorders**: Changes in RNA modification processes have been observed in conditions such as Alzheimer’s disease.

### 3. Drug Interactions
Currently, there are no specific drugs or drug classes directly known to interact with the SNORD83A gene. However, drugs that target processes involved in ribosome biogenesis or RNA modification could potentially influence aspects related to SNORD83A's function. For example, certain chemotherapeutic agents could affect the overall cellular ribosome production.

### 4. Pathways and Biological Processes
SNORD83A is primarily involved in several biological processes, including:

- **Ribosomal RNA processing**: Modulates the post-transcriptional modification of rRNA, which is critical for proper ribosome assembly and function.
- **rRNA methylation**: Functioning as a guide for methylation of rRNA, which plays a crucial role in stabilizing ribosome structure.
- **Regulation of gene expression**: By influencing ribosome biogenesis, SNORD83A may indirectly affect the overall protein output of cells, impacting various cellular pathways.

### Conclusion
In summary, the SNORD83A gene is a small nucleolar RNA involved in the modification and processing of ribosomal RNA, important for ribosome biogenesis. Its associations with specific genes are primarily centered around ribosomal protein genes, and while there is no direct evidence linking it to aging or specific drugs, it holds a potential relevance to age-related processes through its role in ribosome function. Further research is necessary to elucidate the full extent of its biological implications and potential associations with diseases.