### FGF14-IT1 Gene Overview

**Gene Symbol:** FGF14-IT1  
**Gene Type:** Long non-coding RNA (lncRNA)  
**Location:** This gene is located on chromosome 13.

#### General Functions

FGF14-IT1 is associated with the regulation of important cellular processes through mechanisms involving gene expression modulation and RNA processing. While the gene does not code for a protein, its influence on cellular pathways and interactions with other genes suggests a functional role in various biological contexts.

### 1. Associated Genes

FGF14-IT1 is known to be associated with several other genes, particularly those involved in neuronal functions and development. While specific genes are not typically listed in summaries, lncRNAs like FGF14-IT1 often interact with or regulate nearby genes, notably those related to growth factors such as FGF14 (Fibroblast Growth Factor 14). Other potential associated genes based on proximity and functional roles include **FGF1**, **FGF2**, and possibly other members of the **FGF (Fibroblast Growth Factor)** family.

### 2. Aging and Age-Related Diseases

Research indicates that lncRNAs, including FGF14-IT1, can play roles in aging mechanisms and may be involved in age-related diseases. While specific findings on FGF14-IT1 and aging are limited, its association with FGF signaling pathways suggests involvement in cellular stress responses and differentiation, processes highly relevant to age-related pathologies such as neurodegeneration. Potential implications in age-associated disorders, like Alzheimer's, could stem from disrupted signaling that affects neuronal health.

### 3. Drug Interactions

As of the latest data, specific drugs or drug classes interacting directly with FGF14-IT1 have not been widely documented. However, given its role in FGF pathways, it may indirectly interact with therapeutics targeting **FGF receptors** or related growth factor pathways, including agents used for cancer treatments or neuroprotective drugs that target neuronal cell survival.

### 4. Pathways and Biological Processes

FGF14-IT1 is implicated in several key biological pathways and processes:

- **Neurodevelopment:** Involved in neuronal differentiation and development, reflecting its connection to the FGF family.
- **Cell Growth Regulation:** Plays a role in pathways that manage cellular growth and proliferation, which may be altered in cancer.
- **Response to Stress:** May contribute to cellular responses under stress conditions, potentially impacting longevity and resilience in neuronal tissues.
- **Epigenetic Regulation:** As an lncRNA, FGF14-IT1 may engage in chromatin remodeling and gene expression modifications.

In summary, while FGF14-IT1 is a long non-coding RNA with emerging roles in gene regulation and disease processes, ongoing research is required to fully elucidate its specific mechanisms of action and relevance to human health and disease, particularly in the context of aging and therapeutic potential.