### Gene Overview

**Gene Symbol:** CFL1P8  
**Gene Type:** It is a protein-coding gene related to the cytoskeletal dynamics in cells.

### Additional Associated Genes

CFL1P8, also known as a pseudogene of the CFL1 gene (Cofilin 1), has associations with various other genes involved in cytoskeletal regulation and dynamics. Some of these associated genes may include:

- **CFL1 (Cofilin 1):** As the parent gene from which CFL1P8 is derived.
- **ACTB (Beta-actin):** Related to the actin filament dynamics.
- **GAPDH (Glyceraldehyde-3-phosphate dehydrogenase):** Involved in metabolic processes that could also relate to cytoskeletal functions.
- **VCL (Vinculin):** Associated with the linking of actin to integrins in the cytoskeleton.
  
This pseudogene may not directly code for proteins, but it can be involved in regulatory networks alongside these functionally related genes.

### Aging and Age-related Diseases

While there may not be extensive or direct research linking CFL1P8 to aging or age-related diseases, its parental gene, CFL1, has been implicated in various cellular processes relevant to aging. Cofilin is known to regulate actin dynamics, which is critical in cell motility and morphology. As cells age, dysregulation in cytoskeletal dynamics can lead to diseases such as:

- **Neurodegenerative Diseases:** Altered actin dynamics by cofilin has been associated with Alzheimer's disease, indicating a potential indirect linkage through CFL1.
- **Cancer:** Abnormalities in cytoskeletal proteins have been implicated in cancer cell migration and metastasis, which could be influenced by the dysregulation of genes associated with aging.

### Drug Interactions

Currently, no specific drugs or drug classes are distinctly known to interact with the CFL1P8 gene explicitly, mainly due to its status as a pseudogene. However, drugs targeting the cellular cytoskeleton, such as:

- **Cytoskeletal inhibitors (e.g., Cytochalasins, Latrunculin)**
- **Microtubule-targeting agents (e.g., Taxanes)**

may have indirect effects on the pathways involving CFL1, cofilin function, and related actin dynamics, which could be relevant to aging and disease processes.

### Pathways and Biological Processes

CFL1P8 is primarily linked to:

- **Actin Cytoskeleton Organization:** As a pseudogene of CFL1, it may contribute to the regulation of actin dynamics indirectly.
- **Cell Motility:** Cytoskeletal dynamics are crucial for processes involving cell shape change, movement, and division.
- **Signal Transduction:** Acts as a regulatory element affecting how cells respond to signaling pathways involving the cytoskeleton.
- **Cell Proliferation and Differentiation:** Involved in pathways that manage cellular growth and differentiation.

In summary, CFL1P8, as a pseudogene, underscores the complexity and regulation involved in cytoskeleton dynamics that are critical for numerous cellular processes and potentially influencing aging and disease states through its relationship with the CFL1 gene and associated pathways. Further research could elucidate more detailed information on its functional implications in various biological contexts.