### DUTP2 Gene Overview

**Gene Symbol**: DUTP2  
**NCBI Gene ID**: Typically, this would be a unique identifier assigned to the DUTP2 gene in the NCBI database, which can provide additional information on its function, location, and associations.

#### 1. Associated Genes
While the specific summaries provided from NCBI and UniProt may not list associated genes, other genes that could be relevant based on functional proximity or shared pathways may include:
- **DUT (Deoxyuridine triphosphate nucleotidohydrolase)**: This gene is related to the metabolism of deoxyribonucleotides and can impact the same substrate levels as DUTP2.
- **RRM1**: Involved in ribonucleotide reductase, a crucial enzyme for DNA synthesis, may share signaling pathways or regulatory mechanisms with DUTP2.
- **DTYMK**: This gene is involved in nucleotide metabolism and may have overlapping biological functions with DUTP2.

#### 2. Aging and Age-related Diseases
Specific details about DUTP2 in relation to aging and age-related diseases may not be widely published, but potential associations can be drawn:
- **Cell Proliferation and Senescence**: The proper functioning of nucleotide metabolism is crucial for cellular replication. Dysfunction may contribute to senescence.
- **Genomic Stability**: Alterations in deoxyribonucleotide levels can result in mutations and genome instability, which are associated with aging and oncogenesis.
- **Age-related diseases**: While specific studies may be limited, disturbances in nucleotide metabolism have been implicated in conditions like cancer and neurodegeneration, potentially linking DUTP2 to these pathways.

#### 3. Drug Interactions
There might not be extensive specific drug interactions directly identified with the DUTP2 gene; however, drugs impacting nucleotide metabolism, such as:
- **Antimetabolites**: Drugs like Gemcitabine or Cytarabine, which are used in cancer therapy, may indirectly impact DUTP2 functions due to their roles in nucleotide synthesis and salvage pathways.
- **Nucleotide analogs**: Drugs that mimic nucleotides may also influence DUTP2 through competitive inhibition or modulation of its activity.

#### 4. Pathways and Biological Processes
DUTP2 is involved in:
- **Nucleotide Metabolism**: Primarily in the hydrolysis of dUTP to dUMP and inorganic phosphate, making it crucial for the deoxynucleotide pool.
- **DNA Repair and Replication**: By managing the levels of dUTP, DUTP2 plays a role in maintaining genomic stability and fidelity during DNA replication.
- **Cellular Response to DNA Damage**: Involved in the cellular response mechanisms that are activated upon DNA damage, ensuring that nucleotides are available for repair processes.

### Conclusion
DUTP2 is a significant player in nucleotide metabolism with potential implications in cellular aging and disease states. However, precise details regarding drug interactions and aging-related research may be an area for further investigation. For precise, cutting-edge data, always refer to current research publications and databases.