### ARPC1BP1 Gene Overview

**Gene Symbol:** ARPC1BP1  
**Location:** Chromosome 15  
**Function:** The ARPC1BP1 gene encodes a protein that plays a role in the actin cytoskeleton remodeling and cellular processes such as endocytosis and signal transduction. The protein is known to interact with the ARP2/3 complex, which is crucial for actin polymerization and cellular dynamics.

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### 1. Associated Genes

While specific interactions may not be thoroughly documented in the provided summaries, the ARPC1BP1 gene is associated with other genes involved in the actin cytoskeleton and cellular processes, including:

- **ARPC1**: A component of the ARP2/3 complex, directly involved in actin nucleation.
- **ACTR2**: Another component of the ARP2/3 complex.
- **CFL1**: Cofilin, which regulates actin dynamics.
- **WASP**: Wiskott-Aldrich syndrome protein, which activates the ARP2/3 complex.

It is also plausible that ARPC1BP1 might be associated with a broader set of genes involved in cytoskeletal structure and dynamics.

### 2. Aging and Age-Related Diseases

Although specific studies directly linking ARPC1BP1 to aging or age-related diseases are limited, disruptions in actin dynamics and cytoskeleton integrity are broadly implicated in many age-related conditions. Alterations in the function of proteins like ARPC1BP1 could potentially impact processes such as:

- **Cellular Senescence**: Changes in the cytoskeleton may affect cell's ability to divide and trigger senescence.
- **Neurodegenerative Diseases**: Disruption in actin remodeling is significant in diseases like Alzheimer's and Parkinson's.
  
Further studies may elucidate the role of ARPC1BP1 in these contexts.

### 3. Drug Interactions

As of the latest data, specific drugs or drug classes that target ARPC1BP1 directly have not been explicitly noted. However, compounds that modulate actin dynamics or impact cytoskeletal organization, such as:

- **Cytochalasins**: These inhibit actin polymerization and may affect pathways involving ARPC1BP1.
- **Latrunculin**: Another agent that disrupts actin filaments.

Research targeting actin-related proteins could indirectly influence the activity or expression of ARPC1BP1.

### 4. Pathways and Biological Processes

ARPC1BP1 is involved in several biological pathways and processes, notably:

- **Actin Cytoskeleton Regulation**: ARPC1BP1 interacts with the ARP2/3 complex to promote actin filament formation.
- **Cytokinesis**: Essential during cell division, as the actin cytoskeleton is crucial for separating daughter cells.
- **Endocytosis**: Involvement in the internalization of membrane particles and receptors.
- **Cell Motility**: The dynamics of actin are essential for cellular movement and migration, impacting processes such as wound healing and immune response.

In summary, ARPC1BP1 plays a significant role in regulating actin dynamics and is likely implicated in various cellular functions and potentially in age-related pathologies, although more specific research may be needed to define these relationships clearly.