### Overview of PPP1R26-AS1

**Gene Symbol:** PPP1R26-AS1  
**Location:** PPP1R26-AS1 is an antisense long non-coding RNA (lncRNA) gene associated with the PPP1R26 (Protein Phosphatase 1 Regulatory Subunit 26) protein-coding gene.

### 1. Associated Genes

While PPP1R26-AS1 is closely tied to the PPP1R26 gene, it may also exhibit associations with the following genes based on its regulatory effects on gene expression:

- **PPP1R26**: The primary partnered gene for PPP1R26-AS1, involved in protein phosphatase activity.
- **Additional protein phosphatase regulatory subunits**, potentially impacting the phosphatase signaling pathways.

### 2. Aging and Age-Related Diseases

The precise role of PPP1R26-AS1 in aging and age-related diseases is still under investigation. However, long non-coding RNAs, in general, are known to be involved in:

- Regulation of cellular senescence.
- Modulation of stress responses that can impact aging.
- Potential roles in age-related disorders such as Alzheimer's disease or certain cancers, although detailed studies specifically linking PPP1R26-AS1 to these conditions may be limited.

### 3. Drugs or Drug Classes

Currently, there are no specific drugs or drug classes explicitly documented to interact with PPP1R26-AS1 in available databases. However, the regulatory mechanisms of lncRNAs suggest that they could indirectly influence the efficacy or action of drugs targeting gene expression pathways, particularly in the context of protein phosphatase activity.

### 4. Pathways and Biological Processes

**Biological Processes:**
- **Gene Regulation**: As an lncRNA, PPP1R26-AS1 may function as a regulator of gene expression, possibly through epigenetic mechanisms or interaction with transcription factors.
- **Phosphatase Activity Regulation**: It may be involved in modulating pathways related to protein phosphorylation, given its association with PPP1R26.

**Pathways:**
- **Cell Signaling Pathways**: Implications in pathways involving phosphatases and kinases, which are crucial for numerous cellular functions.
- **Cell Cycle and Proliferation**: Potential involvement in pathways that regulate cell division and growth, although specific pathways require further elucidation.

### Conclusion

PPP1R26-AS1 is an important lncRNA associated with the PPP1R26 gene, likely playing a significant role in the regulation of cellular processes through modulation of phosphatase activity. Ongoing research may uncover more precise associations with aging, age-related diseases, and therapeutic implications. Further studies will also help clarify its functional roles and interactions within broader biological contexts.