### TBC1D3P3 Gene Overview

**Gene Symbol:** TBC1D3P3  
**Official Name:** TBC1 domain family member 3 pseudogene 3

#### 1. Associated Genes
The TBC1D3P3 gene is a pseudogene and shares homology with TBC1D3 and other members of the TBC1 domain family, which are involved in various cellular processes, primarily related to the regulation of small GTPases involved in vesicular trafficking. While detailed associations with specific genes beyond TBC1D3 may not be extensively cataloged, homologs and related genes in the TBC1 family can include:

- **TBC1D3**: The functional paralog that is likely to be more biologically relevant.
- **TBC1D1**: Another TBC domain-containing protein involved in insulin signaling and vesicle transport.
- **TBC1D4 (AS160)**: Plays a role in glucose transporter translocation in response to insulin signaling.

#### 2. Aging and Age-related Diseases
As a pseudogene, TBC1D3P3's contribution to aging or age-related diseases may not be directly studied. However, its homologs, particularly TBC1D3 and TBC1D4, are implicated in metabolic pathways that can influence aging. Altered vesicular trafficking and signaling pathways have been associated with metabolic disorders and age-related decline. Research on the TBC1D family suggests that disruptions in their function could potentially contribute to conditions such as Type 2 diabetes and obesity, which are connected to the aging process.

#### 3. Drug Interactions
Due to its classification as a pseudogene, TBC1D3P3 itself is not typically a direct target for drugs. However, drugs that target pathways related to its functional homologs (e.g., TBC1D3 and TBC1D4) may indirectly relate to processes in which TBC1D3P3 is involved. For example:

- **Insulin sensitizers** (like Metformin) could affect the functional pathways that involve TBC1D3 and have indirect implications for TBC1D3P3.
- **Antidiabetic agents**: Interactions that modify insulin receptor signaling pathways may relate back to TBC1 family members, including TBC1D3P3.

#### 4. Pathways and Biological Processes
While TBC1D3P3 is a pseudogene and may not be directly involved in active pathways, its functional analogs and the TBC1 family play crucial roles in several biological processes:

- **Regulation of vesicle trafficking**: TBC1 family proteins participate in the management of endosomal and lysosomal recycling, influencing membrane dynamics and cargo transport.
- **Insulin signaling pathway**: TBC1D4 (AS160) is directly involved in the regulation of glucose transporter translocation to the membrane in response to insulin.
- **GTPase activity**: Proteins in the TBC1 domain family regulate small GTPases like Rab proteins, which are critical for vesicular transport processes.

In summary, while TBC1D3P3 itself may not hold significant direct functional roles due to its status as a pseudogene, its relationships with other genes, particularly in the TBC1 family, indicate its proximity to pathways involved in vesicular trafficking, metabolism, insulin signaling, and potentially the complexities of aging and related diseases. Further research may shed more light on any elusive functional aspects of TBC1D3P3 or its implications in health and disease.