### SNORA70I Gene Summary

**Gene Symbol**: SNORA70I

**Overview**: SNORA70I, also known as small nucleolar RNA (snoRNA), is part of the C/D box class of snoRNAs, which are primarily involved in the biogenesis of ribosomes by guiding the methylation of rRNA and other nucleolar RNAs. SnoRNAs generally play a crucial role in the processing and modification of rRNA, thereby influencing ribosome production and protein synthesis.

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### 1. Associated Genes
While specific associations may not have been fully detailed in the summaries provided, snoRNAs like SNORA70I are often involved with other genes that are part of ribosome biogenesis, RNA modification, and overall gene expression regulation. Other snoRNAs typically show interactions or correlations with genes encoding proteins responsible for processing rRNA, such as:

- **NOP58** and **NOP56**: These are nucleolar proteins involved in the assembly of snoRNP complexes.
- **FBL**: This gene encodes a protein that is a core component of snoRNPs and is important for snoRNA function.

### 2. Aging and Age-Related Diseases
Research regarding SNORA70I specifically related to aging or age-related diseases is quite limited. However, given its function in ribosome biogenesis, alterations in snoRNAs, including SNORA70I, may contribute to cellular senescence and decline in proteostasis, which are hallmarks of aging. Dysregulation of ribosomal RNA modifications has been implicated in some age-related diseases, with potential indirect associations to the activity or expression of snoRNAs.

### 3. Drug Interactions
As of the latest data, there are no specific drugs or drug classes directly known to interact with SNORA70I. However, it is essential to note that compounds affecting nucleolar function or RNA processing more broadly may have indirect effects on the expression or activity of snoRNAs.

### 4. Pathways and Biological Processes
SNORA70I is involved in several key biological processes, primarily concerning ribosome biogenesis:

- **Ribosome biogenesis**: As a snoRNA, SNORA70I is involved in the processing and modification of ribosomal RNA (rRNA), which is essential for the formation of functional ribosomes.
- **RNA methylation**: It is implicated in guiding the methylation of specific nucleotide residues in rRNA, a critical modification that impacts rRNA stability and function.
- **Nucleolar organization**: Being a nuclear component, its activity is involved in the structural organization of the nucleolus, a subnuclear body responsible for rRNA synthesis and ribosome assembly.

Overall, further research may provide deeper insights into the role of SNORA70I in health and disease, particularly with respect to aging, but the current understanding encompasses its fundamental role in ribosome biogenesis and RNA modifications.