### RNU1-149P Gene Overview

**Gene Symbol:** RNU1-149P  
**Gene Type:** RNA, Non-coding (specifically, a small nucleolar RNA, snoRNA)

#### 1. Associated Genes
While specific associations can be variable in different studies, snoRNAs often have functional relationships with other RNA-modifying or ribosome biogenesis-related genes. In some contexts, RNU1-149P may have interactions with:

- **RNU1-1**: Another snoRNA that may function in a similar capacity within nucleolar processes.
- **DKC1**: A gene that encodes a protein involved in the biogenesis of snoRNAs, including modifications related to RNA stability and maturation.
  
(Note: This might vary depending on the biological focus and specific interactions studied.)

#### 2. Aging and Age-Related Diseases
As a small nucleolar RNA, RNU1-149P is involved in the modification of ribosomal RNA and may play a role in gene regulation. While specific aging studies directly linking RNU1-149P to age-related diseases are scarce, snoRNAs can influence cellular homeostasis and stress responses which are pivotal in aging. Hence, dysregulation of such snoRNAs could potentially contribute to age-related conditions, including:

- **Cancer**: Alterations in snoRNA expression profiles are associated with various tumors, possibly influenced by aging.
- **Neurodegenerative Diseases**: Imbalances in non-coding RNAs including snoRNAs may impact neuroinflammation and protein synthesis implicated in diseases such as Alzheimer’s.

Specific detailed studies focusing on RNU1-149P and its role in these conditions would be needed for elucidation.

#### 3. Drug Interactions
As of the current knowledge up to October 2023, specific drugs or drug classes explicitly known to interact with RNU1-149P are not well documented. However, as a snoRNA, it may interact indirectly with drugs that target pathways involved in RNA processing or ribosome assembly. For example:

- **Antisense Oligonucleotides (ASOs)**: These may target snoRNAs for modification or knockdown.
  
Further research into RNA-targeted therapies and their impact on snoRNA could provide insights into potential drugs interacting with RNU1-149P.

#### 4. Pathways and Biological Processes
RNU1-149P is implicated in:

- **Ribosome Biogenesis**: It is involved in the modification of rRNA, crucial for the assembly and function of ribosomes.
- **RNA Modification**: It contributes to the methylation and pseudouridylation of ribosomal and other RNAs.
- **Gene Expression Regulation**: SnoRNAs play roles in the regulation of gene expression through RNA processing mechanisms.

In summary, RNU1-149P is a non-coding RNA with significant roles in ribosome biogenesis and RNA modification processes, potentially linked to aging and various diseases, although specific associations may require further exploration. There’s currently limited direct information on drug interactions specific to this gene, highlighting a need for more targeted research in this area.