### SNORD114-3 Gene Overview

**Gene Symbol:** SNORD114-3  
**Gene Type:** Small nucleolar RNA (snoRNA)  
**Function:** SNORD114-3 is part of the C/D box snoRNAs, which primarily function in the modification of other RNAs, particularly ribosomal RNA (rRNA). This modification often involves 2'-O-methylation and is essential for the proper processing and maturation of rRNA.

### 1. Associated Genes
While specific associations of SNORD114-3 with other genes may not be broadly characterized in current summaries, small nucleolar RNAs, including SNORD114-3, often exert regulatory effects on ribosomal RNA processing and modification. However, SNORD114-3's direct interactions may not be well-documented outside of its multifunctional role in rRNA processing. You may also explore related snoRNA genes such as SNORD114 family members (e.g., SNORD114-1, SNORD114-4) which may share similar vicinities or functional implications.

### 2. Aging and Age-Related Diseases
Current literature does not extensively detail the role of SNORD114-3 in aging or age-related diseases specifically. However, snoRNAs are implicated in cellular functions that are essential for ribosome biogenesis, and disruptions in these processes can lead to cellular senescence and affect overall organismal aging. Some studies indicate that changes in snoRNA expression could be linked to age-related cellular decline, but specific associations of SNORD114-3 itself with particular aging phenotypes or diseases remain to be clarified.

### 3. Drug Interactions
As of October 2023, there are no specific drugs or drug classes known to directly interact with SNORD114-3. However, any pharmacological agent that alters cellular mechanisms involving ribosome biogenesis or RNA processing could have indirect effects on the functionality of snoRNAs, including SNORD114-3.

### 4. Pathways and Biological Processes
SNORD114-3 is involved in several biological processes, particularly:
- **rRNA Methylation:** As a C/D box snoRNA, SNORD114-3 is involved in the 2'-O-methylation of rRNA, which is critical for the stability and functionality of ribosomes.
- **Ribosome Biogenesis:** The snoRNA participates in the maturation and processing of pre-ribosomal RNA.
- **Gene Expression Regulation:** Through its influence on rRNA modifications, SNORD114-3 indirectly affects the translation processes and overall gene expression levels.

Effective ribosome synthesis and function are fundamental for protein translation, ultimately impacting cellular growth, proliferation, and response to stress—key aspects of aging and cellular homeostasis. 

### Conclusion
SNORD114-3 is an essential component of the cellular machinery responsible for ribosome assembly and function. Its precise implications in aging, drug interactions, and specific genetic associations warrant further investigation to understand its full biological significance.