### Overview of RNU6-365P Gene

**Gene Symbol:** RNU6-365P  
**Description:** RNU6-365P is classified as a small nucleolar RNA (snoRNA), which plays a critical role in the modification and processing of other RNAs, particularly pre-ribosomal RNA. snoRNAs are often involved in guiding the modification of nucleotides in rRNA and other small nuclear RNAs (snRNAs).

### Associated Genes

While specific information regarding genes directly associated with RNU6-365P is limited in the summaries provided, snoRNAs such as RNU6-365P may exhibit regulatory interactions with several other genes involved in RNA processing and ribosome biogenesis. They are typically associated with genes encoding ribosomal proteins and components of the nucleolar machinery. Specific co-expressed or functionally related genes can include:

- **RNU6-1:** Another member of the U6 family of snoRNAs.
- **RPL and RPS genes:** Genes that encode ribosomal proteins may show interdependence with snoRNA activity for ribosome assembly.

### Aging and Age-Related Diseases

While the direct impact of RNU6-365P on aging or age-related diseases is not well-characterized, small nucleolar RNAs have been implicated in various cellular processes that are relevant to aging. These processes include:

- **Ribosome biogenesis:** Altered ribosomal RNA processing due to changes in snoRNA function might contribute to cellular senescence.
- **Cell cycle regulation:** Given that the synthesis of ribosomal components is integral to cell proliferation, dysfunction in snoRNA processes might correlate with age-related decline in tissue regeneration and function.

More specific studies would be needed to elucidate concrete associations between RNU6-365P and aging or specific age-related diseases.

### Drug Interaction

As of the provided information, there are no well-documented specific drugs or drug classes that directly interact with the RNU6-365P gene itself. However, drugs that target RNA processes, such as small molecules affecting RNA splicing or transcription, could indirectly influence snoRNA activity, including RNU6-365P.

### Pathways and Biological Processes

RNU6-365P is involved in several important biological processes, including:

- **Pre-rRNA processing:** RNU6-365P is involved in the cleavage and modification of pre-rRNA, which is essential for the maturation of rRNA molecules that constitute the ribosomal subunits.
- **SnoRNA-mediated RNA modification:** The gene plays roles in directing post-transcriptional chemical modifications of RNA, particularly in the context of methylation and pseudouridylation of rRNA.

Overall, RNU6-365P is a key player in the snoRNA family associated with rRNA processing and modification, essential for maintaining ribosomal biogenesis and cellular function. Additional research would shed more light on its specific implications in aging and disease contexts, as well as its interactions with pharmacological agents.