The SEZ6L-AS1 gene, also known as "SEZ6L antisense RNA 1," is classified as a long non-coding RNA (lncRNA) and is located on chromosome 22. This gene is part of a class of RNA molecules that do not code for proteins but play significant regulatory roles in gene expression and cellular processes.

### 1. Associated Genes
SEZ6L-AS1 has been associated with several other genes, particularly those involved in cellular functions and signal transduction. Some of the notable genes related to SEZ6L-AS1 include:
- **SEZ6L**: The gene from which SEZ6L-AS1 derives its name and is likely involved in cellular signaling and development.
- **EXOSC5**: An essential component of the exosome complex, playing a role in RNA processing and degradation.
- Genes involved in pathways related to neurodevelopment and neural function may also interact with the SEZ6L-AS1 or be indirectly regulated by it.

### 2. Aging and Age-related Diseases
Research has suggested that lncRNAs like SEZ6L-AS1 might play roles in various biological processes, including those related to aging and age-related diseases:
- SEZ6L-AS1 has been implicated in neurodegenerative processes, which are linked to aging and conditions such as Alzheimer's disease.
- Dysregulation of lncRNAs, including SEZ6L-AS1, has been associated with cellular senescence and aging-related pathways.
- The gene may contribute to the modulation of inflammation, oxidative stress, and other mechanisms known to influence age-related decline.

### 3. Drug Interactions
As a long non-coding RNA, SEZ6L-AS1 does not directly code for proteins that can serve as traditional drug targets. However, it may be involved in regulatory networks that interact with drugs targeting the associated genes. Currently, there are no specific drugs or drug classes directly known to interact with SEZ6L-AS1. Its role may rather involve broader modulations in cellular contexts, potentially influencing the effectiveness of treatments for conditions like Alzheimer's disease or other neurodegenerative diseases.

### 4. Pathways and Biological Processes
SEZ6L-AS1 is involved in several biological processes and pathways, including:
- **Neurodevelopment and neuronal signaling**: The gene has been implicated in the regulation of neuronal genes, which may affect differentiation and function within the nervous system.
- **Cellular stress responses**: It may play a role in mediating responses to cellular stress.
- **Epigenetic regulation**: Long non-coding RNAs are often involved in chromatin remodeling and the regulation of gene expression through epigenetic mechanisms.

In summary, the SEZ6L-AS1 gene is a lncRNA with potential associations with aging and neurodegenerative processes. It interacts with various genes and may play roles in significant biological pathways, although direct links to drug interactions and specific actionable insights may require further research.