### RNU1-155P Gene Summary

**Gene Symbol:** RNU1-155P  
**Type:** Non-coding RNA (ncRNA)

RNU1-155P is classified as a small nucleolar RNA (snoRNA), which typically participate in the modification and processing of ribosomal RNA (rRNA). These small nucleolar RNAs play critical roles in guiding the methylation and pseudouridylation of rRNAs, thereby contributing to the biogenesis of ribosomes and overall protein synthesis.

### Associated Genes
While RNU1-155P is primarily categorized as a snoRNA, it does not have a robust association with specific protein-coding genes as might be the case with other genes. However, snoRNAs are often involved in larger complexes with proteins involved in rRNA processing and ribosome assembly. Consequently, RNU1-155P could be indirectly associated with various genes involved in ribosomal function and RNA processing, such as:

- **NOP58** (Nucleolar Protein 58 kDa)
- **FBL** (Fibrillarin)

### Aging and Age-Related Diseases
As of October 2023, there is limited direct research on RNU1-155P specifically in the context of aging or age-related diseases. However, snoRNAs, in general, have been implicated in cellular stress responses and age-related declines in ribosomal function. Alterations in snoRNA expression have been observed in conditions such as cancer and neurodegenerative diseases, suggesting that RNU1-155P may play an indirect role in such processes through its influence on ribosomal RNA modification and cellular homeostasis.

### Drug Interactions
Currently, there are no specific drugs or drug classes noted to directly interact with RNU1-155P. Nonetheless, since it is a non-coding RNA involved in rRNA modifications, its function might be influenced in general terms by drugs that affect the ribosomal machinery or nucleolar function, such as:

- **Antibiotics targeting ribosomes** (e.g., aminoglycosides, macrolides)
- **Cytotoxic agents used in cancer therapy** which may affect overall RNA synthesis.

### Pathways and Biological Processes
RNU1-155P is involved in various pathways and biological processes, including:

- **Ribosome biogenesis**: As a snoRNA, RNU1-155P aids in the processing and modification of rRNAs which is essential for the assembly of functional ribosomes.
- **rRNA methylation**: It plays a role in guiding specific methylation patterns on rRNA, which is vital for proper ribosomal function and protein synthesis.
- **Small nucleolar RNA (snoRNA) pathways**: It is part of the larger categories of snoRNA catalyzing rRNA modifications which are crucial in maintaining the integrity of the ribosomal structure.

Overall, RNU1-155P operates at a fundamental level within cells, and while specific details regarding its associations with particular diseases and therapeutic interactions remain limited, its integral roles in ribosome biogenesis and cellular function suggest a broader relevance in biological processes and potential implications in various conditions. Further research may elucidate more specific connections as the field of non-coding RNA continues to expand.