### NFYC-AS1 Gene Overview

**Gene Symbol:** NFYC-AS1  
**Entrez Gene ID:** 100506145  
**Location:** Chromosome 1

#### Gene Description
NFYC-AS1 (Nuclear Factor Y Complex Subunit C Antisense 1) is a long non-coding RNA (lncRNA) that is involved in the regulation of gene expression. It is associated with NFYC, a gene that encodes a subunit of the nuclear factor Y complex, which is crucial for the regulation of various cellular processes, including transcription.

### 1. Associated Genes
While specific associations may vary by study, NFYC-AS1 is generally linked with the following genes due to its regulatory roles:
- **NFYC:** The primary gene encoded for the nuclear factor Y complex subunit C which plays a role in gene transcription.
- **其他相关基因：** Other genes that might be indirectly related through regulatory networks include those involved in cell cycle regulation, apoptosis, and possibly stress responses. More specific associations may come from functional studies or gene expression analyses.

### 2. Aging and Age-Related Diseases
While specific research directly linking NFYC-AS1 to aging or age-related diseases may be limited, the following points are noteworthy:
- **Gene Regulation:** NFYC, the gene this antisense RNA regulates, has been associated with cellular growth, proliferation, and survival. Dysregulation of such genes can be linked to age-related disorders, including cancer and degenerative diseases.
- **Longevity Studies:** Some studies involving lncRNAs and NFYC suggest that expression levels may modulate aging pathways, although direct evidence for NFYC-AS1 remains to be clarified.

### 3. Drug Interactions
Currently, specific drugs or drug classes interacting directly with NFYC-AS1 are not well-documented. However, there are some points to consider:
- **Cancer Therapeutics:** Given the association of NFYC and its regulatory role in cell proliferation, compounds that target pathways related to NFYC (e.g., anti-cancer drugs, epigenetic modulators) might indirectly affect the expression and function of NFYC-AS1.
- **Potential Future Research:** As research evolves, the identification of lncRNA-targeting therapeutics may find some lncRNAs playing roles in drug responses. 

### 4. Pathways and Biological Processes
NFYC-AS1 is involved in several important biological processes and pathways, including:
- **Gene Expression Regulation:** As an antisense lncRNA, NFYC-AS1 can regulate the transcription of NFYC and possibly other nearby genes through transcriptional interference or chromatin remodeling.
- **Cell Cycle Regulation:** Given the role of NFYC in the regulation of the cell cycle, NFYC-AS1 may contribute to cellular growth and differentiation processes.
- **Apoptosis:** NFYC is implicated in apoptosis pathways, suggesting that NFYC-AS1 may have roles in cell survival and death mechanisms.

### Conclusion
The NFYC-AS1 gene is an important regulatory lncRNA associated with NFYC and potentially relevant to processes involved in aging and disease. While direct drug interactions are not prominently documented, its role in gene regulation highlights its potential significance in therapeutic contexts, especially in cancer biology. Further research will elucidate its specific functionalities and clinical relevance.