### SNORD45A Gene Overview

**Gene Symbol:** SNORD45A  
**Full Name:** Small Nucleolar RNA, C/D Box 45A  
**NCBI Gene ID:** 9651

#### General Description
SNORD45A is a small nucleolar RNA (snoRNA) that belongs to the C/D box class of snoRNAs, which are primarily involved in the modification and processing of ribosomal RNA (rRNA) and, in some cases, other RNA molecules. These snoRNAs guide the 2'-O-methylation of target nucleotides in rRNA and other RNA species, influencing their processing and modification, which is crucial for ribosome assembly and function.

### Associated Genes
As of the latest data, there are no specific genes directly associated with SNORD45A mentioned in the NCBI or UniProt summaries. However, snoRNA genes often exist within clusters and may associate indirectly with members of the ribosomal mitochondrial gene family. Other snoRNAs and nearby genes encoding ribosomal proteins may be co-regulated.

### Aging and Age-Related Diseases
Currently, there is limited direct evidence linking SNORD45A specifically to aging or age-related diseases. Nonetheless, given that snoRNAs, including SNORD45A, play critical roles in the proper processing of rRNA, their dysregulation might be implicated in conditions such as cancer. In some cases, altered expression of snoRNAs has been observed in various age-related diseases, including neurodegenerative disorders, but specific knowledge regarding SNORD45A’s direct role in aging remains unclear.

### Drug Interactions
As of the latest updates, there are no specific drugs or drug classes documented to interact with SNORD45A directly. Being a snoRNA, it is less likely to have direct pharmacological targets compared to protein-coding genes. However, any disruptions in the processes regulating rRNA and snoRNA could potentially be influenced by therapeutic agents that target ribosomal function or RNA synthesis.

### Pathways and Biological Processes
SNORD45A is primarily involved in the following biological processes:
- rRNA methylation (specifically the 2'-O-methylation of ribosomal RNA).
- Ribosome biogenesis and assembly, impacting protein synthesis.
- Potentially involved in processing other non-coding RNAs and modulating their functions.

Specific pathways associated with SNORD45A include those related to ribosome biogenesis, nucleolar function, and RNA processing pathways. 

### Conclusion
In summary, SNORD45A is a small nucleolar RNA that is crucial for ribosomal RNA modification, thus playing a significant role in ribosome biogenesis and function. While there is limited knowledge about its direct involvement in age-related conditions or drug interactions, it remains an important element in the intricate network of RNA processing and ribosomal function within cells. Further research would be beneficial to elucidate its precise roles and potential implications in health and disease.