The GUCY2EP gene, also known as guanylate cyclase 2E, is primarily associated with the mammalian olfactory system. Here’s a detailed overview based on your specific queries:

### 1. Associated Genes
GUCY2EP is part of a larger family of guanylate cyclase genes. While the specific associations for GUCY2EP may not be extensively characterized, other related genes include:
- **GUCY1A3**: This gene encodes another guanylate cyclase involved in phototransduction in the retina.
- **GUCY2A**: Known for its role in the inner ear and possibly influencing sensory perception.
- **GUCY2B**: Functioning in the cardiovascular system.
While not directly associated, the overarching guanylate cyclase family may bear relevance, particularly regarding their involvement in signaling pathways related to nitric oxide and sensory perception.

### 2. Aging and Age-related Diseases
Currently, there are no well-characterized direct associations between GUCY2EP and aging or specific age-related diseases in humans. However, since the gene is a pseudogene in humans and most primates, it suggests that its functional loss may reflect evolutionary adaptations rather than direct implications for age-associated decline or diseases. There are studies suggesting alterations in sensory perception with aging, but these have not been definitively linked back to GUCY2EP.

### 3. Drug Interactions
As GUCY2EP has become a pseudogene in humans, it is unlikely to have specific drug interactions. However, drugs that influence the nitric oxide signaling pathway or guanylate cyclase activity in other contexts could theoretically interact with the broader family of this gene. Examples of drug classes that might be relevant include:
- **Guanylate Cyclase Stimulators**: Such as riociguat, which are primarily used to treat cardiovascular diseases by enhancing the NO-cGMP signaling pathway. 
- **Phosphodiesterase Inhibitors**: These may indirectly affect the pathways that include guanylate cyclases by altering cGMP levels.

### 4. Pathways and Biological Processes
The GUCY2EP gene, through its functional analogs and relatives, is involved in several key biological processes and pathways:
- **Olfactory Signal Transduction**: As a part of the olfactory system, it is involved in the detection of odorous molecules and subsequent sensory signaling.
- **cGMP Metabolism**: Like other guanylate cyclases, it is part of the pathway that converts GTP into cGMP, a second messenger, which plays a crucial role in various signaling cascades, including vasodilation and neural signaling.
- **Chemosensation**: The primary biological function pertains to the chemosensory processes that allow organisms to respond to chemical stimuli in their environment, particularly in the context of olfactory sensitivity in rodents.

### Summary
While GUCY2EP plays a vital role in rodent olfactory systems, it has become a pseudogene in humans and thus has limited functional relevance in humans, with implications more centered around evolutionary biology rather than direct clinical significance. Further research may illuminate any potential connections to broader physiological processes or disease states, especially as they relate to chemosensory function.