### PPIAP90 Gene Overview:

**Gene Symbol:** PPIAP90  
**Full Name:** Peptidylprolyl Isomerase A (Cyclophilin A) Like Protein 1 (PPIAP90 gene).  

PPIAP90 is a gene that encodes a member of the cyclophilin protein family, which are peptidylprolyl isomerases that catalyze the isomerization of proline residues in peptides. These proteins are involved in various cellular processes, including protein folding, signaling, and cellular stress response.

### 1. Associated Genes:
While the direct associations of PPIAP90 are not typically well-documented outside specific studies, cyclophilins, including PPIAP90, generally have interactions with other genes related to protein folding and stress response. Some related genes could include:

- **PPIA** (Peptidylprolyl Isomerase A)
- **PPIB** (Peptidylprolyl Isomerase B)
- **FKBP1A** (FK506 Binding Protein 1A)
- **HSP90AA1** (Heat Shock Protein 90 Alpha Family Class A Member 1) 

There may be additional regulatory or downstream interaction partners based on specific cellular contexts and experimental observations.

### 2. Aging and Age-Related Diseases:
Research has indicated that alterations in the function of peptidylprolyl isomerases, including PPIAP90, may be implicated in aging and age-related diseases such as:

- **Neurodegenerative Diseases:** There’s emerging evidence suggesting that the dysregulation of cyclophilins may contribute to neurodegenerative pathways, such as those found in Alzheimer’s and Parkinson’s diseases.
- **Cardiovascular Aging:** PPIAP90 may also play roles in cellular repair processes essential for maintaining heart health during aging.

Involvement in aging-related processes may also hinge on its function in cellular stress responses and protein folding pathways.

### 3. Drug Interactions:
While specific drugs targeting PPIAP90 directly are not typically well-known, cyclophilins, in general, have interactions with pharmacological agents such as:

- **Cyclosporin A:** A potent immunosuppressive drug known to inhibit the activity of cyclophilins, including PPIAP90.
  
- **Other Immunosuppressive Drugs:** Some other drugs may interact indirectly due to overlapping functional roles in cellular stress response mechanisms.

### 4. Pathways and Biological Processes:
PPIAP90 is involved in several key biological pathways and processes, including, but not limited to:

- **Protein Folding and Isomerization:** Its primary function as a peptidylprolyl isomerase is to assist in protein folding—a crucial process for proper cellular function.
- **Cell Survival and Stress Response:** The protein is involved in cellular responses to stress, potentially influencing apoptotic pathways and survival under stress conditions.
- **Immune Response:** Cyclophilins generally have roles in immune modulation, which may link PPIAP90 to various immune system processes.
- **Signaling Pathways:** Involvement in cellular signaling pathways, particularly those related to apoptosis and immune responses.

In summary, PPIAP90 is a gene coding for a cyclophilin-like protein crucial in several cellular functions, with implications in aging, immune response, and potentially neurodegenerative pathways. Further detailed research may elucidate more specific interactions and functional significance.