**SNORD115-23 Gene Overview:**

**Gene Symbol:** SNORD115-23

**Description:**
SNORD115-23 is a member of the SNORD115 family of small nucleolar RNAs (snoRNAs), which are primarily involved in the modification and processing of ribosomal RNA. These snoRNAs are thought to function in the regulation of gene expression and splicing. SNORD115-23 is part of a larger locus that has been implicated in certain neurological disorders, including personality disorders and some aspects of autism spectrum disorder.

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### 1. Associated Genes:
While specific genes directly associated with SNORD115-23 may not be extensively documented, the snoRNA family often interacts with:

- **PRMT5** - Protein arginine methyltransferase that may be involved in RNA processing pathways.
- **U3 snoRNA** - Another snoRNA, involved in pre-rRNA processing which might share regulatory roles.
- **Other members of the SNORD115 family** (e.g., SNORD115-10) could also be considered related due to their overlapping functions in ribosome biogenesis.

### 2. Aging and Age-related Diseases:
While there is no direct evidence linking SNORD115-23 to aging itself, its involvement in neural processes and disorders that usually manifest in later life may suggest a potential connection. Research has indicated that alterations in snoRNA expression, including those belonging to the SNORD115 family, could affect neural development and function. Some age-related neurodegenerative diseases could share mechanisms that alter the regulation of snoRNA expression or function, thus potentially implicating SNORD115-23 indirectly.

### 3. Drug Interactions:
There is limited information regarding specific drugs directly interacting with SNORD115-23. However, generally, compounds that target SNORD-related pathways may include:

- **Antidepressants** - Some studies suggest that the expression of snoRNAs can be modulated by SSRIs (Selective Serotonin Reuptake Inhibitors), which could alter their activity in neurological contexts.
- **Antipsychotic medications** - As snoRNAs are implicated in neurodevelopmental conditions, certain antipsychotics may influence their regulatory networks.

### 4. Pathways and Biological Processes:
SNORD115-23 is primarily involved in pathways related to:

- **Ribosome biogenesis** - As a snoRNA, it plays a critical role in the modification and processing of rRNA constituents required for ribosome formation.
- **Gene expression regulation** - It may help fine-tune the expression of specific genes, particularly those involved in CNS function and development.
- **Cellular responses to stress** - Given the context of neurodevelopment and potential interactions with other regulatory RNAs, it may participate in cellular pathways linked to stress responses in neurons.

In summary, SNORD115-23 plays a role in essential cellular processes, particularly in the central nervous system. The potential implications for aging and neurodevelopmental disorders require further research to clarify the precise mechanisms involved.