The **F11-AS1** gene, also known as **F11 antisense RNA 1**, is a long non-coding RNA (lncRNA) that plays a regulatory role in various biological processes. Below are more detailed insights based on your request:

### 1. Associated Genes
While the provided summary from NCBI and UniProt might not mention specific genes associated with F11-AS1, in general, lncRNAs like F11-AS1 can interact with various protein-coding genes to regulate their expression. Some genes that have been associated with F11-AS1 in the literature or databases include:

- **F11**: The protein-coding gene that encodes the coagulation factor XI, which is directly related to blood clotting.
- Other genes within neuronal, cardiovascular, or hematological contexts may also be associated as F11-AS1 may have significance in those pathways.

### 2. Aging and Age-Related Diseases
The F11-AS1 gene has been implicated in various cellular processes that can be relevant to aging and age-related diseases:

- **Role in thrombosis and cardiovascular diseases**: Abnormalities in coagulation factor XI, the protein associated with the F11 gene, may relate to age-related thrombosis, a leading cause of cardiovascular diseases.
- **Inflammation and longevity**: Some studies suggest that lncRNAs like F11-AS1 may have roles in regulating inflammation, which is a significant determinant of aging and age-related diseases.

### 3. Drug Interactions
Currently, direct drug interactions specifically targeting F11-AS1 are not well-documented. However, given that F11-AS1 regulates the expression of F11, drugs related to coagulation, anticoagulant therapies (e.g., **rivaroxaban**, **apixaban**) might indirectly interact or be influenced by the expression levels of this lncRNA due to its role in coagulation pathways.

### 4. Pathways and Biological Processes
F11-AS1 is involved in several biological processes and pathways including:

- **Regulation of gene expression**: As a long non-coding RNA, it can function as a molecular sponge for miRNAs, influencing the expression of target mRNAs.
- **Hematological processes**: Given its connection with F11, it is implicated in blood coagulation pathways.
- **Neuronal survival and functionality**: Some functional studies suggest a potential role in the nervous system, impacting neuronal health and possibly influencing neurodegenerative conditions.
- **Inflammatory response**: As a regulatory element, it may play a role in modulating inflammatory pathways, potentially linking it to both aging and age-related diseases.

### Conclusion
Overall, F11-AS1 is an important regulatory element connected with coagulation and potentially relevant to age-related conditions, chiefly through its influence on the expression of the F11 gene and other associated pathways. However, further research is needed to fully elucidate the specific biological roles and mechanisms involving this lncRNA. Always consult the latest literature and databases for up-to-date and in-depth biological information.