### RNU2-64P Gene Overview:

**Gene Symbol:** RNU2-64P

**Description:** RNU2-64P is a small nuclear RNA (snRNA) gene. It belongs to the U2 RNA family, which plays a crucial role in the splicing of pre-mRNA in eukaryotic cells. This process involves the removal of introns and joining of exons to produce mature messenger RNA (mRNA). The precise role of RNU2-64P in splicing and gene regulation continues to be an area of ongoing research.

### 1. Associated Genes:

Details on associated genes with RNU2-64P are not typically documented extensively in available summaries, but snRNA genes often have interdependencies with various spliceosome components, such as:
- **SNRNP70:** Involved in the formation of a functional spliceosome.
- **SNRNP200:** Plays a role in the unwinding of pre-mRNA and recruitment of spliceosomal U2 and U5 snRNPs.
- **PRPF8:** A key component of the spliceosome essential for splicing.
(This list may not be exhaustive, as specific interactions can vary based on the context of studies.)

### 2. Aging and Age-Related Diseases:

While there is currently no direct evidence linking RNU2-64P specifically to aging or age-related diseases, general trends in snRNA function suggest potential associations:
- **RNA Processing and Aging:** Aberrant RNA splicing has been implicated in age-related diseases such as Alzheimer’s disease, where misregulation of splicing factors has been observed.
- **Gene Expression Modulation:** Changes in the expression levels of snRNAs, including U2 family members, have been associated with cellular senescence and decline in proliferative capacity in aging cells.

### 3. Drug Interactions:

There are currently no specific drugs or drug classes that are known to interact directly with RNU2-64P. However, since it is involved in RNA processing and splicing, it may be indirectly affected by drugs that target splicing mechanisms or RNA metabolism. Compounds such as splice-switching oligonucleotides or small molecules that modulate splicing have been explored in therapeutic contexts (e.g., drug therapies for certain genetic disorders).

### 4. Pathways and Biological Processes:

RNU2-64P is primarily involved in the following biological processes:
- **mRNA Splicing:** As a part of the spliceosome, it helps in the excision of introns and ligation of exons during the maturation of pre-mRNA.
- **Gene Regulation:** By participating in RNA processing, it indirectly affects gene expression profiles.
- **Nuclear RNA Processing:** Plays a role in the broader context of nuclear pre-mRNA processing pathways.

### Conclusion:

RNU2-64P is a small nuclear RNA gene with potentially significant roles in mRNA splicing and regulation. Although direct links to aging and specific drug interactions are limited, the gene's involvement in RNA processing pathways could implicate it in broader biological contexts, including those related to age-related pathologies. Further investigations into this gene's precise functions and associations will enhance our understanding of its contribution to cellular processes.