### NAV2-AS3 Gene Overview

**Gene Symbol**: NAV2-AS3  
**Synonyms**: NAV2 Antisense RNA 3

**Function**: NAV2-AS3 is an antisense RNA gene associated with the NAV2 gene. Antisense RNAs often play regulatory roles in gene expression, impacting protein production and possibly influencing transcriptional and post-transcriptional mechanisms.

### Associated Genes

NAV2-AS3 is primarily associated with the NAV2 gene, which is implicated in neuronal development and may play a role in neural pathology. Additional genes of interest that may also show associations via regulatory networks include:

- **NAV1**: Related to neuronal development.
- **UBR5**: Involved in protein degradation and potentially in neural related processes.
- **PTBP1**: A   splicing factor that may cross-talk with NAV2's pathways.

*Note*: The specific interactions can be context-dependent and may not be clearly established yet.

### Aging or Age-Related Diseases

Current research regarding the NAV2-AS3 gene in the context of aging or age-related diseases is limited. However, given its association with NAV2, which has been implicated in neurodegenerative diseases, a broader investigation may suggest potential involvement in:

- **Neurodegenerative Disorders**: Conditions such as Alzheimer's disease, where improper regulation of RNA may contribute to aberrant protein aggregation and neuronal degeneration.
- **Age-Related Cognitive Decline**: Antisense RNA regulation may influence mechanisms underlying synaptic plasticity and cognitive function.

### Drug Interactions

To date, there is no specific information about drugs or drug classes known to directly interact with NAV2-AS3. However, since NAV2 is implicated in neuronal function, research into neuroprotective agents and drugs targeting neurodegenerative pathways may ultimately reveal indirect associations.

### Pathways and Biological Processes

NAV2-AS3 is involved in several biological processes:

- **Regulation of Gene Expression**: As an antisense RNA, NAV2-AS3 likely plays a role in the transcriptional regulation of its sense partner, NAV2.
- **Neuronal Development**: It may have a regulatory role in processes involved in brain development and function.
- **Cellular Response to Stimuli**: The gene may be involved in cellular response mechanisms, especially related to neuronal activity.

### Conclusion

While specific details regarding NAV2-AS3's roles in aging and drug interactions remain relatively sparse, its potential implications in neuronal regulation and development may be critical. Further research could illuminate its role in age-related pathologies and possible therapeutic pathways.