### Summary of PPP1R35-AS1 Gene

**Gene Symbol:** PPP1R35-AS1  
**Gene Type:** Long Non-Coding RNA (lncRNA)  
**Location:** Located on chromosome 1, this gene is known as a long non-coding RNA and is associated with the regulation of gene expression.

### 1. Associated Genes

While PPP1R35-AS1 primarily relates to its role as a long non-coding RNA, it may have regulatory interactions with a variety of genes involved in cellular processes and signaling pathways. Additional genes that have been associated with PPP1R35-AS1 include:

- **PPP1R35** (Protein Phosphatase 1 Regulatory Subunit 35): This is the protein-coding gene located adjacent to PPP1R35-AS1, which could suggest a regulatory relationship between the lncRNA and its neighboring gene.
- **TP53**: Some studies have suggested associations with tumor suppressor genes such as TP53, given the role of lncRNAs in cancer regulation.

### 2. Aging and Age-Related Diseases

Research on the exact role of PPP1R35-AS1 in aging and age-related diseases is limited but the involvement of lncRNAs in cellular senescence, inflammation, and stress response could suggest potential roles for PPP1R35-AS1. Some general insights include:

- Potential involvement in cellular stress responses which can impact aging processes.
- Associations with cancer progression and metastasis when considering its interactions with p53 and other oncogenic pathways.

### 3. Drug Interactions

Currently, there is limited information available concerning specific drugs or drug classes that directly interact with PPP1R35-AS1. However, due to its regulatory nature, it might indirectly affect the pharmacodynamics of drugs targeting:

- **Cancer pathways:** Since lncRNAs like PPP1R35-AS1 are implicated in cancer biology, they could indirectly influence responses to chemotherapeutic agents by modulating the expression of critical genes involved in survival pathways.

### 4. Pathways and Biological Processes

PPP1R35-AS1 is believed to be involved in several biological processes and pathways:

- **Regulation of Gene Expression**: Being a long non-coding RNA, it likely plays a role in modulating the transcription of adjacent or related genes.
- **Cell Cycle Regulation**: LncRNAs are often implicated in the cell cycle, potentially influencing cell proliferation and apoptosis.
- **Signal Transduction**: It may participate in various signaling pathways, possibly affecting pathways related to cell growth and differentiation.

### Conclusion

PPP1R35-AS1 is a long non-coding RNA with regulatory functions likely associated with processes such as gene expression modulation and involvement in cellular stress responses. Although specific connections to aging and drug interactions are still emerging, its proximity to functionally relevant genes such as PPP1R35 points to a role in important biological pathways. Further research is needed to fully elucidate its functional implications in aging and disease.