RNU6-158P is a gene that belongs to the class of small nucleolar RNAs (snoRNAs). Generally known as a pseudogene of the U6 snRNA family, it participates in the biogenesis and maturation of small nuclear ribonucleoproteins (snRNPs) through guiding complex modifications of other RNAs, particularly pre-mRNA.

### 1. Associated Genes:
RNU6-158P itself does not directly associate with other genes in terms of known pathways or metabolic processes. However, other snoRNAs and components of the spliceosomal machinery may have interactions in broader regulatory networks during biological and developmental processes. For instance, other members of the U6 family or snoRNA genes such as U3, U8, and the U13 snoRNA might share functional roles or regulatory interactions during RNA processing, though these interactions require further exploration in research on specific pathways.

### 2. Aging and Age-Related Diseases:
The role of RNU6-158P specifically in aging or age-related diseases is not well characterized. However, alterations in snoRNA expression or function have been linked to various age-related phenomena. Aberrant splicing or defects in snRNP processes can contribute to a range of disorders, including neurodegenerative diseases such as Alzheimer's and age-related macular degeneration. Further research might uncover specific impacts of RNU6-158P in such contexts.

### 3. Drug Interactions:
As of now, there are no specific drugs or drug classes reported that directly interact with the RNU6-158P gene. However, several drugs that target RNA-related processes, splicing mechanisms, or general RNA metabolism may indirectly affect the expression and function of snoRNAs, including RNU6-158P. This includes drugs used to treat cancer or viral infections that may alter cellular RNA processing.

### 4. Pathways and Biological Processes:
RNU6-158P is involved in various biological processes, primarily related to RNA processing and modification. Key pathways include:
- **RNA Splicing:** RNU6-158P contributes to the splicing of pre-mRNA through its role in the assembly and functioning of spliceosomal complexes.
- **SnoRNA Biogenesis and Function:** It is part of the larger family of snoRNAs that facilitate 2'-O-methylation and pseudouridylation of target RNAs, functions integral to ribosome biogenesis and RNA maturation processes.
- **Cognitive Functions and Neural Development:** Although indirect, snoRNAs, including pseudogenes like RNU6-158P, might influence neuronal RNA processing, thus potentially playing a role in cognitive health across the lifespan.

In summary, while RNU6-158P is a recognized component of the RNA processing machinery, its specific contributions, especially in the context of aging, novel drug interactions, and direct associations with other genes, remain areas for further investigation.