### NCAM2 Gene Summary

**Gene Symbol:** NCAM2  
**Full Name:** Neural Cell Adhesion Molecule 2  
**Location:** Human Chromosome 16

#### Description:
The NCAM2 gene encodes a protein that is a member of the immunoglobulin superfamily, specifically comprising the neural cell adhesion molecules. This protein is a type I transmembrane protein and is involved in cell adhesion processes. NCAM2 plays a critical role in the development of the nervous system, particularly in the selective fasciculation (bundling) and zone-to-zone projection of primary olfactory axons, which are critical for olfactory system functionality. 

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### 1. Associated Genes
While NCAM2 may not have extensive direct associations mentioned in general summaries, studies often reveal relationships between NCAM2 and several other genes involved in neuronal development and function, such as:
- **NCAM1** (Neural Cell Adhesion Molecule 1)
- **L1CAM** (L1 Cell Adhesion Molecule)
- **Contactin** (multiple genes such as CNTN4)
These genes share roles in neuronal adhesion and signaling processes.

### 2. Aging and Age-Related Diseases
Although direct associations of NCAM2 with aging are not widely documented, general findings suggest that neuronal cell adhesion molecules, including NCAM2, may play a role in neurodegenerative processes. These may involve:
- **Cognitive Decline:** NCAM2 is implicated in neural differentiation and plasticity, which are processes that might be affected during aging, potentially impacting cognitive functions.
- **Alzheimer's Disease:** Some studies suggest that neural cell adhesion molecules might be linked to neurodegenerative diseases, including Alzheimer's, through disruptions in cell adhesion processes, though direct evidence for NCAM2 specifically is limited.

### 3. Drug Interactions
As of my last training data in October 2023, specific drug interactions directly with NCAM2 are not well-characterized, although drugs affecting neuronal function, such as antipsychotics or antidepressants, may indirectly influence NCAM2-related pathways. Additionally, therapeutic approaches targeting related pathways in neurodegenerative diseases may also impact NCAM2 functionality, although detailed drug classes specifically listed for NCAM2 interaction are currently not established.

### 4. Pathways and Biological Processes
The NCAM2 gene is involved in several biological processes, including but not limited to:
- **Neurogenesis:** Plays a critical role in the growth and development of neuronal cells.
- **Cell Adhesion:** Facilitates cell-cell interactions, critical for neuronal network formation.
- **Olfactory Signaling:** Specifically involved in the development of olfactory pathways and sensory perception.
- **Synaptic Plasticity:** Likely contributes to mechanisms underlying learning and memory by influencing synaptic connectivity and strength.

### Concluding Notes
NCAM2 is a significant player in neural development and connectivity. Research into its implications in aging and disease is ongoing and may lead to new insights relevant to neurobiology and potential therapeutic applications. Further studies are required to fully elucidate its role in advanced biological and clinical contexts.