### C8orf34-AS1 Gene Overview

**Gene Symbol:** C8orf34-AS1  
**Location:** Chromosome 8, on the opposite strand to the C8orf34 gene, making it an antisense RNA.

#### 1. Associated Genes
C8orf34-AS1 is known to be associated with several other genes, particularly those involved in regulatory functions and gene expression. Some of the associated genes include:

- **C8orf34** (as the gene is located adjacent to this gene)
- **MIR4300** (microRNA that may interact with C8orf34-AS1 due to their genomic proximity)
- Other genes related to regulatory functions and non-coding RNAs may also be identified in specific studies, although most associations are still being investigated.

#### 2. Aging and Age-Related Diseases
While direct studies on C8orf34-AS1 in the context of aging are limited, non-coding RNAs like C8orf34-AS1 often play roles in gene regulation that could impact aging and age-related diseases:

- **Regulatory Role:** As a long non-coding RNA, C8orf34-AS1 could influence the expression of neighboring genes, some of which may be implicated in aging pathways or age-related diseases.
- **Potential Connections:** There are suggestions from some studies that non-coding RNAs like C8orf34-AS1 may be involved in cellular senescence and age-related inflammation, although direct evidence regarding this gene remains under investigation.

#### 3. Drug Interactions
Currently, there is no specific drug or drug class explicitly known to interact with C8orf34-AS1. Given that it is an emerging area of research, future studies may identify specific small molecules or therapeutic strategies that could impact its expression or function.

#### 4. Pathways and Biological Processes
C8orf34-AS1 is involved in various biological processes where long non-coding RNAs play critical regulatory roles:

- **Gene Regulation:** Non-coding RNA such as C8orf34-AS1 can modulate the expression of messengers from protein-coding genes, impacting various cellular processes.
- **Transcriptional Regulation:** It may influence transcription factor activity or chromatin remodeling, affecting gene expression patterns.
- **Cell Growth and Proliferation:** Involvement in cellular pathways that regulate proliferation and apoptosis is often characteristic of lncRNAs, and this gene could play a role in these processes as well.

### Summary
The C8orf34-AS1 gene is an antisense long non-coding RNA that may have implications in gene regulation and potentially links to aging and age-related diseases through its interactions with neighboring genes. While currently there are no specific drug interactions associated with this gene, ongoing research may illuminate its potential roles in health and disease pathways. Further studies will be beneficial in exploring these aspects in-depth.