**Gene Overview: ART2P**

**Gene Symbol**: ART2P

The ART2P gene (ADP-ribosyltransferase 2, pseudogene) is a pseudogene located on the human genome. It is closely related to the functional ART2 gene, which encodes a protein involved in the modification of proteins through ADP-ribosylation, a post-translational modification that can alter protein function and interactions.

### 1. Associated Genes:
While ART2P is a pseudogene and does not produce a functional protein, it is homologous to the ART2 gene. ART2 is associated with various immune responses and is located in proximity to other genes involved in immune signaling. Notable genes potentially linked to ART2P include:
- ART1: ADP-ribosyltransferase family member involved in cellular signaling.
- CD2: A surface marker on T-cells and NK cells, which may work in concert with ART2 in immune regulation.

### 2. Aging and Age-related Diseases:
While direct information linking ART2P to aging or specific age-related diseases is limited due to its pseudogene status, the functional counterpart (ART2) has been implicated in various immune responses. Changes in immune function with age (immunosenescence) could theoretically involve components such as ART2; thus, alterations in ADP-ribosylation processes could have implications for age-related immune dysfunctions, though this requires further investigation.

### 3. Drug Interactions:
As ART2P itself is a pseudogene and does not encode a protein involved in signaling or metabolic pathways, there are currently no known drugs or drug classes that interact specifically with this gene. However, because ART2 is involved in responses to immune-modulating drugs, studies on ART2 could provide indirect insights.

### 4. Pathways and Biological Processes:
The ART2P pseudogene may not be directly involved in pathways since it does not produce a functional protein. However, related pathways that involve the ART2 gene include:
- ADP-ribosylation of proteins, which plays a role in various cellular processes such as apoptosis, DNA repair, and cell signaling.
- Immune response pathways, particularly in the context of T-cell activation and regulation.

Overall, while ART2P itself lacks substantial direct functional implications due to its status as a pseudogene, understanding its relationship with the ART2 gene and other genes in the immune system may provide insight into broader biological processes and disease mechanisms.