### MIR4456 Gene Overview

**Gene Symbol:** MIR4456  
**Type:** MicroRNA (miRNA)  

#### 1. Associated Genes:
While the primary role of the MIR4456 gene as a microRNA is to regulate the expression of various target genes, specific interactions with target genes beyond those explicitly cited in summaries are typically identified through experimental studies. Notably, miRNAs can regulate numerous genes, and the interactions may vary in different tissues or physiological conditions. Potential target genes can include those involved in cell cycle regulation, apoptosis, development, and stress responses, although specific targets for MIR4456 are often determined through research specific to the context of study.

#### 2. Aging and Age-Related Diseases:
While there might not be extensive direct research specifically linking MIR4456 to aging or age-related diseases noted by pre-October 2023 sources, it is known that miRNAs, in general, play significant roles in the regulation of aging processes and the mechanisms underlying age-related diseases. Dysregulation of certain miRNAs has been observed in conditions such as Alzheimer’s disease, cardiovascular diseases, and cancer. Further research on MIR4456 may uncover specific roles in these contexts, especially regarding cellular senescence or the response to oxidative stress.

#### 3. Drug Interactions:
As of the latest available data, there are no specific drug interactions directly linked to MIR4456. However, it is important to consider that miRNAs can influence the efficacy and resistance of various drugs by modulating the expression of drug transporters, metabolic enzymes, or targets. Thus, understanding the regulatory networks involving MIR4456 may yield insights into how it could impact pharmacological effectiveness indirectly.

#### 4. Pathways and Biological Processes:
MIR4456 is likely involved in several biological processes, including:

- **Post-Transcriptional Gene Regulation:** As an miRNA, MIR4456 is primarily involved in the regulation of gene expression at the mRNA level.
- **Cell Proliferation and Differentiation:** MiRNAs generally play roles in regulating pathways related to cell growth and differentiation.
- **Apoptosis:** Many miRNAs regulate apoptotic pathways, and MIR4456 may interact with genes involved in cell death.
- **Stress Responses:** miRNAs are often implicated in the cellular responses to various stresses (e.g., oxidative, nutrient).

Additionally, common signaling pathways that might be influenced by MIR4456 include the MAPK pathway, Wnt signaling pathway, and pathways related to inflammation and immune responses, although specific involvement may depend on context and tissue.

### Conclusion:
MIR4456 is a microRNA implicated in various regulatory functions within cells. Much of its specific functional involvement, especially in relation to aging, diseases, and drug interactions, remains to be further elucidated through targeted research.