### SNORD45C Gene Summary

**Gene Symbol:** SNORD45C

**NCBI Summary:**
SNORD45C (small nucleolar RNA, C/D box 45C) is categorized as a small nucleolar RNA (snoRNA) involved in the methylation of ribosomal RNA (rRNA). snoRNAs play essential roles in the processing and modification of other non-coding RNAs.

### 1. Associated Genes
While specific associations may not always be documented in standard summaries, *SNORD45C* is generally considered to be a part of the C/D box snoRNA family, which can include other snoRNA genes that work in concert during the rRNA modification process. Related genes within this family may include:

- **SNORD45A**
- **SNORD45B**
- Other C/D box snoRNAs, which often co-localize or share similar functions in rRNA methylation.

### 2. Aging and Age-related Diseases
As of October 2023, direct links between SNORD45C and aging or age-related diseases may not be explicitly characterized in literature. However, since snoRNAs like SNORD45C are critical for the proper functioning of the ribosome and protein synthesis, alterations in RNA modification processes can correlate with aging and may contribute to age-related pathologies, such as:

- Neurodegenerative diseases
- Cancer
- Cellular senescence

Research on snoRNAs, in general, indicates they may influence cellular function in aging cells, although specific mechanistic studies involving SNORD45C are limited.

### 3. Drug Interactions
Currently, there are no specific drugs or drug classes explicitly reported to interact with SNORD45C. The function of snoRNAs does not typically lend itself to direct drug targeting. However, as the field evolves, it's essential to monitor emerging research that could define any pharmacological relevance.

### 4. Pathways and Biological Processes
SNORD45C is involved in several biological processes, particularly those related to:

- **Ribosome Biogenesis:** As a snoRNA, it is involved in the modification of pre-rRNA to produce mature rRNA components essential for ribosome assembly.
- **RNA Processing:** It plays a role in the processing of rRNA, which is necessary for the formation of ribosomal subunits.
- **Nucleolus Organization:** snoRNAs contribute to the structural and functional integrity of the nucleolus, where rRNA processing occurs.

Understanding these processes provides insights into the essential roles that snoRNAs play in maintaining cellular homeostasis and the implications for disease states when these processes are disrupted.

### Summary
SNORD45C is a small nucleolar RNA with a pivotal role in rRNA modification and ribogenesis. While its direct implications in age-related diseases and drug interactions remain limited, its essential functions link it to broader biological processes critical for cellular health and functioning. Further research may elucidate more detailed roles and associations related to aging and disease.