The A2M-AS1 gene, short for "Alpha-2-macroglobulin antisense RNA 1," encodes a long non-coding RNA (lncRNA) that is transcribed from the antisense strand of the Alpha-2-macroglobulin (A2M) gene. lncRNAs play critical roles in gene regulation, chromatin modification, and cellular processes, with implications in various biological functions and diseases.

### 1. Associated Genes
While the specific summaries provided may not identify associated genes, lncRNAs like A2M-AS1 often interact with various genes and regulatory pathways. A2M-AS1 is particularly relevant in the context of:
- **A2M**: The protein-coding gene for Alpha-2-macroglobulin, which involved in a wide array of physiological and pathological processes, including protease inhibition and immune response.
- Other neighboring lncRNAs or genes in related pathways may also be implied but not explicitly cited without experimental data.

### 2. Aging and Age-Related Diseases
Research has indicated that A2M-AS1 may have associations with:
- **Aging**: Expression levels of lncRNAs, including A2M-AS1, have been shown to fluctuate with age, affecting cellular senescence and tissue regeneration processes.
- **Age-Related Diseases**: Aberrant expression of lncRNAs has been linked to various age-related diseases, including Alzheimer's disease, cardiovascular diseases, and cancers. Studies on A2M-AS1's role in these contexts remain under investigation but may reveal contributions to the pathology of these conditions.

### 3. Drug Interactions
Currently, the literature does not extensively detail specific drugs or drug classes directly interacting with A2M-AS1. However, its role in regulation may have implications for treatments targeting:
- **Inflammation**: Given the involvement of Alpha-2-macroglobulin in the immune response, lncRNA regulation might indirectly affect responses to anti-inflammatory medications.
- **Oncology**: Given the link between lncRNAs and cancer progression, therapies that downregulate or modulate lncRNA levels may have indirect relevance.

### 4. Pathways and Biological Processes
A2M-AS1 is suspected to play roles in numerous biological processes including, but not limited to:
- **Gene Expression Regulation**: Acting as a regulator of the expression of underlying protein-coding genes, particularly A2M.
- **Cellular Proliferation and Apoptosis**: Potential influences on cell survival and growth pathways, especially in the context of cancer wherein altered lncRNA levels can impact tumorigenesis.
- **Immune Response Modulation**: With A2M being a critical component in immune regulation, A2M-AS1 may participate in modulating immune responses.

With ongoing research, further elucidation of A2M-AS1's precise functions and interactions within these contexts is expected. This gene exemplifies the functional diversity of lncRNAs in health and disease.