### GMDS-DT Gene Overview

**Gene Symbol**: GMDS-DT  
**Description**: The GMDS-DT gene is a non-coding RNA gene that is believed to play a role in regulating the expression of the GMDS (GDP-mannose 4,6-dehydratase) gene, which is involved in the biosynthesis of GDP-mannose, an important sugar nucleotide that plays a vital role in glycosylation pathways.

### 1. Associated Genes
- **GMDS**: The primary gene associated with GMDS-DT is GMDS, which encodes an enzyme critical for the synthesis of GDP-mannose.
- **Other potential associations** include genes involved in glycosylation pathways and metabolic processes related to carbohydrate metabolism, although specific genes other than GMDS may require further exploration based on experimental data.

### 2. Aging and Age-Related Diseases
Current literature does not indicate a direct association of the GMDS-DT gene with aging or specific age-related diseases. However, disturbances in glycosylation pathways—which involve GDP-mannose—have been linked to various disorders, including:
- Developmental disorders.
- Cardiovascular diseases.
- Immune system-related diseases, which can worsen with age.

Further research might elucidate more precise roles of GMDS-DT in these contexts.

### 3. Drug Interaction
As of the last knowledge update (October 2023), specific drugs specifically targeting GMDS-DT or directly interacting with it have not been clearly defined in available databases. However, drugs or compounds that influence glycosylation patterns may impact the pathway in which GMDS and thus GMDS-DT is involved:
- **Drug Classes** potentially affecting glycosylation include:
  - Glycosyltransferase inhibitors.
  - Agents altering sugar nucleotide pools, which affect overall glycosylation.

### 4. Pathways and Biological Processes
GMDS-DT is primarily involved in the following biological processes and pathways:
- **Glycosylation**: Plays a regulatory role impacting glycan synthesis which is fundamental for cell signaling and recognition.
- **Metabolic pathways** involving carbohydrate metabolism, specifically in the synthesis of GDP-mannose.
- **Response to stress**: Though this is indirect, as alterations in glycosylation can affect how cells react to various stressors.

### Summary
Overall, the GMDS-DT gene serves as a regulatory non-coding RNA associated with the GMDS gene, playing a potential role in critical biosynthetic processes. Its implications for aging and disease remain an area for future research, particularly surrounding disorders linked to aberrant glycosylation.