### PPFIA2 Gene Overview
The **PPFIA2** gene encodes a member of the liprin family, which are proteins known for their role in cell signaling, particularly in the context of neuronal function and development. The gene is crucial for axonal guidance and plays roles in mammary gland development through its interaction with protein-tyrosine phosphatases (PTPs).

### Gene Associations
While the NCBI and UniProt summaries focus on the PPFIA2 gene itself, it is known to interact with various other genes and proteins, notably:
- **CASK** (Calcium/Calmodulin-dependent serine protein kinase), which is crucial for synaptic function.
- **PTPRF** (Protein Tyrosine Phosphatase Receptor Type F), where PPFIA2 alters its cellular localization and clustering.
- Other members of the LAR family of PTPs, although specific gene names outside those mentioned in the summaries may not be well-documented.

### Aging and Age-Related Diseases
Current research has not extensively linked PPFIA2 directly with aging mechanisms or specific age-related diseases, but:
- Alterations in neuronal scaffolding proteins are often implicated in neurodegenerative diseases.
- Given PPFIA2's role in synaptic function and dendritic spine stability, dysregulation has the potential to contribute to cognitive decline associated with aging or conditions such as Alzheimer’s disease.

### Drug Interactions
There are no specific drugs or drug classes directly associated with PPFIA2 mentioned in the provided summaries. However, due to its involvement in intracellular signaling pathways and its potential impact on neuronal function, drugs targeting synaptic transmission or related pathways could indirectly interact with PPFIA2 functions.

### Pathways and Biological Processes
PPFIA2 is involved in several biological processes, including:
- **Axon Guidance**: It helps in the proper formation and guidance of neuronal axons, critical during nervous system development.
- **Synaptic Plasticity**: It plays a role in dendritic spine structure, essential for synapse formation and stability in neurons.
- **Cell Adhesion**: PPFIA2 may influence focal adhesion dynamics, impacting how cells adhere to each other or their extracellular matrix.
- **Scaffolding**: Acts as a scaffolding protein that organizes signaling molecules at synapses.

### Conclusion
In summary, the PPFIA2 gene encodes a protein that is vital for neuronal development and synaptic function through interactions with other signaling proteins. Although details on aging and drug interactions are limited, it remains a significant candidate for further research in neurobiology and associated disorders.