### MPRIP-AS1 Gene Overview

**Gene Symbol**: MPRIP-AS1  
**Location**: MPRIP-AS1 is a long non-coding RNA (lncRNA) gene that is located on chromosome 1 in humans. 

### Gene Function and Characteristics

MPRIP-AS1, or "MPRIP antisense RNA 1," is implicated in various biological processes, particularly those related to gene regulation and modulation of gene expression. It is thought to function in different cellular contexts, often by influencing the activity of neighboring genes.

### 1. Associated Genes

While the summaries from NCBI and UniProt may not list specific associated genes, lncRNAs such as MPRIP-AS1 often interact with neighboring or functionally related genes in regulatory networks. In close proximity, it may be related to the **MPRIP** (Myosin Phosphatase Rho-Interacting Protein) gene itself. Additionally, lncRNAs frequently interact with genes involved in pathways related to cellular growth, differentiation, and apoptosis.

### 2. Aging and Age-Related Diseases

There is limited direct research linking MPRIP-AS1 to aging or age-related diseases. However, lncRNAs in general have been implicated in various aspects of cellular senescence and the aging process. LncRNAs often play roles in the regulation of inflammation, apoptosis, and cellular response, which could be associated with age-related changes and diseases such as cancer, cardiovascular diseases, and neurodegenerative conditions.

### 3. Drug Interactions

Currently, specific drug interactions with MPRIP-AS1 are not abundantly documented. However, given its role in regulating gene expression, it may play an indirect role in how cells respond to various therapeutics, particularly those targeting cellular pathways known to involve lncRNAs. Research into the role of lncRNAs in drug resistance in cancer treatments is ongoing, and while it is not specific to MPRIP-AS1, it may have relevance in broader contexts.

### 4. Pathways and Biological Processes

MPRIP-AS1 is known to be involved in several biological processes, particularly those relating to gene regulation. It may play roles in:

- **Gene expression regulation**: Interactions with transcription factors or chromatin-modifying complexes.
- **Cell signaling pathways**: Particularly those involving muscle contraction and cytoskeletal organization due to the neighboring MPRIP gene's functions.
- **Cellular growth and proliferation**: As it might modulate other genes involved in these pathways.

Research into lncRNA function, including MPRIP-AS1, is still expanding, with ongoing studies aimed at clarifying their roles in health and disease states.

### Summary

To summarize, MPRIP-AS1 is a long non-coding RNA with potential involvement in gene regulation and several biological processes, although further specific research is required to elucidate its role in aging, disease, and drug interactions. Its functional partners and an association with age-related diseases continue to be an area of active investigation.