The TAS1R2 gene encodes a member of the taste receptor family and plays a crucial role in sweet taste perception. Here are additional details about the TAS1R2 gene, along with your requested information:

### 1. Associated Genes
TAS1R2 is part of the sweet taste receptor complex, and it associates with:
- **TAS1R3**: The most significant partner in forming the heterodimeric sweet taste receptor that detects sweet substances.
- Other taste receptor genes, such as **TAS1R1** (which is involved in umami taste), may also be functionally related in broader taste perception contexts.

### 2. Aging and Age-Related Diseases
Research indicates that taste perception can be altered with aging, potentially affecting the quality of life and nutritional intake in older adults. While specific studies directly linking TAS1R2 to age-related diseases are limited, it is known that:
- Altered sweet taste sensitivity has been associated with metabolic disorders, obesity, and diabetes in older populations. 
- Studies suggest that taste receptors, including TAS1R2, may influence metabolic functions and systemic health, which become particularly relevant in age-related conditions like metabolic syndrome.

### 3. Drug Interactions
While there are no specific FDA-approved drugs targeted directly at the TAS1R2 gene, sweet taste perception may be influenced by specific substances:
- **Artificial sweeteners** (including aspartame, sucralose, and saccharin) that primarily target the TAS1R2/TAS1R3 receptor complex.
- The **GLP-1 receptor agonists** (such as liraglutide) utilized for diabetes management, may indirectly influence sweet taste pathways due to their effects on metabolism and appetite.

### 4. Pathways and Biological Processes
The TAS1R2 gene is involved in several biological pathways and processes, including:
- **GPCR signaling pathways**: TAS1R2 functions as a G-protein coupled receptor, which plays a role in transmitting taste signals from the oral cavity to the nervous system.
- **Cytokinesis**: TAS1R2 has been linked to the positive regulation of cytokinesis, the process by which the cytoplasm of a parent cell is divided into two daughter cells during cell division.
- **Taste receptor signaling pathways**: Participation in pathways related to the detection of sweet taste and sensory perception.
  
Additionally, TAS1R2 may interact with metabolic pathways and play a role in nutrient sensing, potentially affecting energy balance and metabolic health.

In summary, the TAS1R2 gene is a pivotal component of the sweet taste receptor machinery with implications for taste perception, nutrition, and possibly broader metabolic and age-related health consequences.