LINC00280, also known as long intergenic non-protein coding RNA 280, is a member of the long non-coding RNA (lncRNA) class of genes. This gene is situated in a long intergenic region, indicating that it does not code for a protein but may have regulatory roles in various biological processes.

### Additional Gene Associations
LINC00280 has been associated with various genes in different contexts, including those involved in regulatory networks, epigenetic modifications, and cellular processes. Some genes that have been noted in association with LINC00280 include:
- **SP1**: Involved in transcription regulation.
- **TP53**: Known for its role as a tumor suppressor.
- **EZH2**: Part of the polycomb repressive complex, influencing gene silencing.

### Aging and Age-related Diseases
While specific details on the association of LINC00280 with aging and age-related diseases may not be robustly characterized in current literature, there are indications that long non-coding RNAs can play a significant role in various aging processes. Some findings suggest that dysregulation of lncRNAs, including LINC00280, can be linked to cellular senescence and may influence pathways related to cancer and other age-associated conditions.

### Drug Interaction
Currently, there is no direct list of specific drugs or drug classes known to interact explicitly with LINC00280. However, lncRNAs are often implicated in drug resistance and responsiveness in cancer therapeutics, so they may be indirectly involved through their modulation of cellular pathways targeted by certain drugs. Ongoing research may uncover more specific interactions.

### Pathways and Biological Processes
LINC00280 is involved in several pathways and biological processes, which may include, but are not limited to:
- **Gene regulation**: It may influence the expression of nearby genes through chromatin remodeling or transcription factor recruitment.
- **Cellular proliferation**: Through interactions that may affect the cell cycle and related signaling cascades.
- **Stem cell maintenance**: Some lncRNAs play critical roles in maintaining pluripotency and regulating differentiation, suggesting that LINC00280 could have similar implications.

Further studies are necessary to elucidate the full spectrum of pathways and biological functions involving LINC00280, particularly in the context of pathophysiological states such as cancer, neurodegeneration, and other age-related diseases. Researchers continue to explore the regulatory roles of lncRNAs, promising new insights into their functional importance.