### LINC01153 Gene Overview

**Gene Symbol:** LINC01153

LINC01153 is classified as a long intergenic non-coding RNA (lincRNA) gene. Non-coding RNAs play a critical role in the regulation of gene expression at various levels, including chromatin remodeling, transcriptional regulation, and post-transcriptional processing.

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### 1. Associated Genes
While specific associations can vary based on the biological context and study, LINC01153 has been suggested to have potential interactions with the following genes:

- **TP53:** Often involved in cell cycle regulation and apoptosis, TP53 may interact with lincRNAs including LINC01153 in cancer pathways.
- **RIPK1:** Related to apoptosis and necroptosis; interactions with lincRNAs can indicate a role in cell death pathways.
- **MYC:** Known for its role in cell growth and proliferation; may interact with LINC01153 in cancer contexts.

It’s important to note that lincRNAs can function in a tissue-specific manner and may not always have direct associations with specific genes.

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### 2. Aging and Age-related Diseases
LINC01153 has been implicated in several studies related to aging and age-related diseases. Research indicates that:

- **Cancer:** Altered expression of LINC01153 has been observed in various cancers, suggesting a potential role in tumorigenesis and progression. Its dysregulation may correlate with biological pathways involved in aging, such as cellular senescence.
- **Neurodegenerative conditions:** Some studies have linked lincRNAs, including LINC01153, to neurodegenerative diseases, hinting at their role in neuroprotection or neuroinflammation during aging.

Understanding the role of LINC01153 in these contexts may elucidate its functions in cellular aging and related disease mechanisms.

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### 3. Drug Interactions
LINC01153 does not have well-established direct drug interactions documented in available databases. However, given its potential involvement in cancer progression and regulation, it can be influenced indirectly by:

- **Chemotherapeutic agents:** Such as doxorubicin or cisplatin, which target pathways that include the functions of lincRNAs like LINC01153.
- **Targeted therapies:** That may affect signaling pathways where LINC01153 has regulatory effects, particularly in cancer treatments.

Research on lncRNA response to drug therapies is an evolving field, and future studies may unveil specific interactions.

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### 4. Pathways and Biological Processes
LINC01153 is involved in several biological processes and pathways, including:

- **Regulation of Gene Expression:** As a lincRNA, it plays a role in modulating gene expression at transcriptional and post-transcriptional levels.
- **Cell Cycle Regulation:** Potential involvement in controlling cell cycle progression, often critical in cancer biology.
- **Apoptotic Signaling Pathways:** It may participate in regulating apoptosis, which is critical for maintaining cell homeostasis and preventing cancer.
- **Inflammatory Response:** Given its association with various diseases, it might influence inflammatory pathways that are particularly relevant in aging and degenerative diseases.

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### Conclusion
In summary, LINC01153 is an important long non-coding RNA with potential roles in gene regulation, aging, cancer progression, and possibly neurodegenerative diseases. While its direct drug interactions remain largely unexplored, its contributions to various pathways highlight the need for further research to clarify its biological relevance and therapeutic potential.