### RNU105C Gene Overview

**Gene Symbol:** RNU105C

**Function:**  
RNU105C is a small non-coding RNA gene that encodes a member of the U6 small nuclear RNA family. These RNA molecules are integral to the splicing of pre-mRNA, playing a vital role in the spliceosome function which is essential for the maturation of mRNA in eukaryotic cells.

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### Associated Genes
RNU105C, as a non-coding RNA, may not have direct associations with other genes in the context of coding genetic material, but it is functionally related to other spliceosomal components and U6 snRNA family members, such as:

- **RNU6-1**: Another member of the U6 snRNA family.
- **RNU6-2**: Closely related to RNU6-1 and is involved in similar splicing-related processes.
- **SNRNPs**: Small nuclear ribonucleoproteins that play roles in mRNA splicing along with U6 snRNA.

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### Aging and Age-Related Diseases
While specific studies directly linking RNU105C to aging or age-related diseases may not be extensively documented, non-coding RNAs in general have been implicated in various regulatory processes associated with cellular aging and senescence. Alterations in splicing mechanisms can lead to the accumulation of defective mRNA, which is a hallmark of several age-related diseases and conditions, including neurodegeneration and cancer. 

### Potential Involvement in Diseases:
- **Cancer:** Aberrant splicing and altered expression of snRNA can contribute to tumorigenesis.
- **Neurodegenerative diseases:** Changes in splicing factors have been linked to perturbed RNA processing in diseases like Alzheimer's.

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### Drug Interactions
As RNU105C is a non-coding RNA, there are typically no direct small molecule drugs specifically targeting this gene. However, drugs that influence RNA splicing or modulate splicing factors might indirectly affect the activity of genes like RNU105C. Examples of these drug classes include:

- **Splicing Modulators:** Compounds that are specifically designed to enhance or inhibit splicing mechanisms (e.g., Eteplirsen, an oligonucleotide that modulates splicing in Duchenne muscular dystrophy).

Because RNU105C functions as part of the spliceosome complex, any drugs that affect spliceosomal components may also influence its activity and the downstream gene expression. 

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### Pathways and Biological Processes
RNU105C is primarily involved in:

- **mRNA Splicing:** Integral to the splicing of pre-mRNAs.
- **Formation of the spliceosome:** RNU105C is a crucial element of the spliceosomal assembly.
- **RNA processing and modification:** Involved in various steps of RNA maturation and quality control.

**Pathways:**
1. **mRNA Splicing - Major Pathway:** This includes the recognition of splice sites and the excision of introns.
2. **RNA Transport:** Influences the transport of mature mRNA from the nucleus to the cytoplasm.

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### Conclusion
RNU105C is an important component in the realm of RNA maturation and spliceosomal assembly. Although specific health condition associations may not be extensively characterized, the critical role of non-coding RNAs in gene regulation suggests potential implications in aging and disease processes. Further studies might elucidate more precise connections between RNU105C and its role in health and disease.