### ACTR3BP6 Gene Overview

**Gene Symbol**: ACTR3BP6  
**Chromosomal Location**: Human chromosome 7  
**Gene Function**: The ACTR3BP6 gene encodes a protein that is part of the Actin-related protein (ARP) complex, which plays a critical role in cytoskeletal dynamics and various cellular processes. It belongs to a family of proteins that interact with actin and are involved in cellular motility and organization.

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### 1. Associated Genes

While the NCBI and UniProt summaries may not mention specific genes directly associated with ACTR3BP6, it is commonly noted that genes involved in similar pathways or complexes may include:

- **ACTR3**: Also encodes an actin-related protein and contributes to the same cellular processes.
- **ACTR2**: Part of the ARP complex and often studied alongside ACTR3BP6.
- **ARP2/3 complex genes**: Such as **ARPC1A**, **ARPC2**, and others that are involved in actin polymerization and cytoskeleton reorganization.

### 2. Aging and Age-Related Diseases

Current research on ACTR3BP6's connection to aging or age-related diseases is not well-established in the literature. However, general studies suggest that proteins involved in cytoskeletal dynamics can impact cellular rejuvenation processes, organelle positioning, and cellular senescence. Disruptions in cytoskeletal integrity have been documented in various age-related conditions, including:

- **Neurodegenerative Diseases**: Alterations in cytoskeletal proteins are critical in diseases like Alzheimer's and Parkinson's.
- **Cancer**: Cellular motility and invasive potential associated with age may be influenced by changes in the actin cytoskeleton.

Further investigations would be required to delineate a direct association between ACTR3BP6 and these processes.

### 3. Drug Interactions

As of the latest available data, no specific drugs or drug classes have been directly documented as interacting with ACTR3BP6. Given its role in the actin cytoskeleton, any potential drug interactions may include:

- **Actin inhibitors**: Such as cytochalasins (e.g., Cytochalasin D), which stabilize or destabilize actin dynamics.
- **Chemotherapeutics**: Some cancer treatments target cellular processes that involve actin dynamics, although direct interactions with ACTR3BP6 have not been specifically reported.

### 4. Pathways and Biological Processes

ACTR3BP6 is implicated in a broad range of biological pathways, including:

- **Cytoskeleton Organization**: Essential for maintaining cellular form and transportation processes.
- **Cell Motility**: Involved in processes like cell migration and invasion.
- **Endocytosis and Vesicle Transport**: Plays a role in the internalization of various substrates and trafficking of organelles.
- **Immune Response**: Contributes to the actin remodeling required for immune cell activation and function.

In summary, ACTR3BP6 is a gene that occupies an important role in the regulation of cytoskeletal dynamics, interacts with multiple genes within the ARP complex, and while its role in aging and drug interactions needs further characterization, it remains an active area of inquiry in cellular biology.