### DPY19L1 Gene Overview

**Gene Symbol:** DPY19L1  
**Location:** Chromosome 3 (3q27.3)  
**Predicted Function:** The DPY19L1 gene is predicted to encode a protein with mannosyltransferase activity, specifically involved in the C-mannosylation of tryptophan residues in target proteins, thereby affecting glycosylation processes.

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### 1. Associated Genes
While direct associations may not always be highlighted in gene summaries, the following are some genes that could be functionally or computationally linked to DPY19L1 based on protein interactions and pathways:

- **DPY19L**: a similar gene involved in similar glycosylation processes.
- **MOGS**: involved in the mannosylation of N-glycans.
- **POMGNT1**: related to glycosylation and muscle disorders.
- **SRD5A2**: associated with steroid metabolism and has potential links due to protein interaction networks.
  
Specific functionalities can overlap with other genes involved in glycosylation pathways or diseases, as DPY19L1 is integral in protein modification.

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### 2. Aging and Age-Related Diseases
Current research indicates that DPY19L1 may play a role in age-related processes, particularly in the context of:

- **Neurodegenerative Disorders**: Altered glycosylation patterns due to dysfunctional C-mannosyltransferases could be implicated in diseases such as Alzheimer's.
- **Muscle-Wasting Disorders**: Glycosylation defects are sometimes observed in sarcopenia (muscle degeneration with age).
- **Cancer**: Changes in glycosylation have been associated with age-related cancer susceptibility and metastasis.
  
However, direct associations with specific aging mechanisms or diseases may require more focused studies.

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### 3. Drug Interactions
Currently, there are no specific drugs or drug classes directly known to interact with DPY19L1. However, the following points can be made:

- **Glycosylation Inhibitors**: Compounds that affect intracellular glycosylation processes may indirectly influence the function of DPY19L1 or its downstream effects.
- **Cancer Therapeutics**: Potential interactions may emerge based on the implications of glycosylation in oncology; drugs targeting protein glycosylation might be relevant. 

It is advisable to consult updated pharmacological databases or recent literature for the most current interactions.

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### 4. Pathways and Biological Processes
DPY19L1 is known to be involved in several key biological processes and pathways:

- **Protein C-linked Glycosylation**: The primary function of DPY19L1 relates to the C-mannosylation process, impacting how proteins interact and function.
- **Cell Adhesion**: The proper glycosylation status guided by DPY19L1 may influence cellular adhesion mechanisms.
- **Developmental Processes**: Altered glycosylation may play a role in embryonic development.

The gene may also be linked to broader pathways involved in cellular signaling, protein stability, and secretion.

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In summary, DPY19L1 is a gene of notable interest within the context of glycosylation, with potential implications for aging-related health and disease. Understanding its interactions and the pathways it influences will require ongoing research efforts.