### CCDC26 Gene Overview

**Gene Symbol:** CCDC26

#### Summary
CCDC26 (Coiled-Coil Domain Containing 26) is a gene that encodes a protein thought to be involved in cellular processes due to its coiled-coil domain structure. While its exact function is not fully characterized, it has been implicated in various cellular functions and disease processes.

### 1. Associated Genes
CCDC26 has been identified to have associations with several other genes, particularly those involved in cancer and cellular pathways. Although specific associations vary from study to study, some of the notable genes include:
- **MIR7-1** (a microRNA that can regulate gene expression)
- **TP53** (a crucial tumor suppressor gene often implicated in tumorigenesis)
- **BRCA1/BRCA2** (involved in DNA repair, mutations lead to breast and ovarian cancers)

### 2. Aging and Age-Related Diseases
There has been research indicating that variations in the CCDC26 gene may be linked to cancer susceptibility, particularly in the context of glioma. Additionally, since cancer risk tends to increase with age, CCDC26 may play a role in age-related oncogenesis. 

Research is ongoing, but some studies suggest that disruption or mutations in CCDC26 may influence cellular aging and tumor biology. Further studies could elucidate its role in other age-related diseases, including neurodegeneration.

### 3. Drug Interactions
As of the latest data available, there are no specific drugs or drug classes explicitly linked to CCDC26. However, due to its association with various cancers, it may be indirectly related to drug classes used in oncological therapeutics, such as:
- **Chemotherapeutic agents** (e.g., alkylating agents, anthracyclines)
- **Targeted therapies** (e.g., PARP inhibitors for BRCA-related tumor types)

Research may continue to explore potential therapeutic avenues associated with CCDC26 in these contexts.

### 4. Pathways and Biological Processes
CCDC26 is involved in several biological processes, including but not limited to:
- **Cell Cycle Regulation**: Its indirect association with cancer suggests involvement in pathways related to cell division and tumorigenesis.
- **Signal Transduction**: While specifics are under investigation, coiled-coil proteins often play roles in mediating signals within cells.
- **DNA Damage Response**: Due to associations with significant tumor suppressor genes and involvement in cellular repair processes.
- **Cellular Structure**: The coiled-coil domain indicates potential involvement in forming protein complexes or cytoskeletal organization.

### Conclusion
CCDC26 is an important gene with roles primarily noted in cancer biology, although its complete biological function remains to be clarified. As it relates to aging and age-associated diseases, ongoing research may reveal deeper insights into its contributions to cellular processes and disease mechanisms. Further studies are also warranted to explore therapeutic implications related to this gene.