**Gene Overview: ARL14EPP1**

**Gene Symbol:** ARL14EPP1  
**Full Name:** ARF-like 14 interacting protein 1  

### Detailed Gene Information:
The ARL14EPP1 gene encodes a protein that is involved in several important cellular functions, particularly those related to the cytoskeleton, cell signaling, and intracellular trafficking.

### 1. Associated Genes:
While specific gene interactions can vary based on biological context, here are several genes and proteins that may have functional associations with ARL14EPP1:
- **ARL14:** This gene encodes a small GTPase involved in cell signaling and cytoskeletal remodeling.
- **RHO family genes** (such as RHOA, RAC1): These genes and their products are closely involved in cytoskeletal dynamics.
- **RAB family members** (e.g., RAB5): Known for their role in vesicular transport and endocytosis.

### 2. Aging or Age-Related Diseases:
Current research associated with ARL14EPP1 suggests potential implications in:
- **Neurodegenerative diseases:** Alterations in ARL-family proteins have been linked to processes involved in neuronal function, which may be affected during aging.
- **Cellular senescence:** As cell signaling pathways alter with age, proteins like ARL14EPP1 may play a role in pathways that lead to cellular aging and senescence.
- **Cancer:** Changes in cytoskeletal dynamics and intracellular trafficking often correlate with malignancies, suggesting that ARL14EPP1 might be investigated in the context of tumor progression and aging.

### 3. Drug Interactions:
Currently, there is limited specific information available regarding drugs or drug classes that directly interact with ARL14EPP1. It may be involved indirectly in pathways affected by treatment targeting small GTPases or in the modulation of cellular transport processes, but specific pharmacological agents are not well-characterized. Ongoing research may reveal more about the interactions that could be relevant for drug discovery.

### 4. Pathways and Biological Processes:
ARL14EPP1 is implicated in several biological processes:
- **Cytoskeletal organization:** Plays a role in the regulation of actin dynamics and microtubule organization.
- **Vesicular transport:** Involvement in endosomal and lysosomal trafficking, helping in the transport of cargo within the cell.
- **Cell signaling:** Participates in signaling pathways that regulate various cellular functions including cell proliferation and differentiation.
- **Pathways:** While specific pathways related to ARL14EPP1 are still being delineated, it is relevant in:
  - **Rho GTPase cycle** - regulating cytoskeletal arrangements.
  - **Endocytosis** - likely linked to processes involving clathrin-mediated pathways.

In summary, the ARL14EPP1 gene plays crucial roles in various cellular processes, and while certain associations with age-related functions exist, more studies are needed to elucidate its specific roles in aging and interactions with drugs or other genes.