### FRMPD1 Gene Overview

**Gene Symbol:** FRMPD1  
**Location:** Plasma membrane  
**Function:** The FRMPD1 gene encodes a protein that is involved in the establishment of protein localization to membranes and the regulation of G protein-coupled receptor signaling pathways. Notably, FRMPD1 stabilizes the membrane-bound protein GPSM1, facilitating its interaction with the G protein subunit GNAI1.

### Other Genes Associated with FRMPD1

While the summaries provided do not mention specific genes beyond GPSM1 and GNAI1, FRMPD1 may interact with or be functionally linked to other genes involved in G protein signaling, membrane trafficking, and cytoskeletal organization. Some associated genes could include:

- **GNAI1**: As mentioned, FRMPD1 interacts with GPSM1 to regulate GNAI1.
- **GPSM1**: A direct interaction and stabilization.
- Other genes associated with G proteins and receptor signaling may include members of the G protein-coupled receptor (GPCR) superfamily, such as various adrenoceptors or muscarinic receptors.

### Aging and Age-Related Diseases

At this time, there are limited specific studies directly linking FRMPD1 to aging or age-related diseases. However, given its role in G protein signaling and membrane dynamics, alterations in FRMPD1 function could contribute to age-related cellular dysfunctions, potentially influencing diseases characterized by changes in cellular signaling, such as neurodegenerative diseases or cardiovascular disorders. Further investigations would be needed to clarify any direct associations.

### Drug Interactions

As of the latest updates, specific drugs or drug classes that interact with the FRMPD1 gene or its protein products have not been prominently characterized in biomedical literature. However, compounds that target G protein signaling pathways or affect GPCRs could indirectly relate to FRMPD1 activity. Pharmacological agents such as modulators of G protein signaling (e.g., G protein-coupled receptor antagonists, allosteric modulators) could theoretically impact pathways influenced by FRMPD1.

### Pathways and Biological Processes

FRMPD1 is involved in several important biological pathways, including:

- **G Protein-Coupled Receptor (GPCR) Signaling Pathway**: FRMPD1 regulates GPCR signaling through its interaction with GPSM1 and GNAI1.
- **Cell Membrane Dynamics**: It is associated with the establishment of protein localization to membranes, thus playing a role in maintaining cellular architecture and functionality.
- **Protein-Containing Complexes**: It forms part of multi-protein complexes that are crucial for signal transduction and cellular responses.
- Potential involvement in cytoskeletal organization, although this would require further verification through experimental studies.

### Summary
The FRMPD1 gene plays an essential role in cellular signaling related to GPCR pathways by stabilizing GPSM1 and interacting with GNAI1. Its potential implications in aging and disease require more thorough examination, and while specific pharmacological interactions are not well-defined, it holds relevance in studies of G protein signaling mechanisms. Further research is warranted to explore its broader biological significance and therapeutic implications.