### SHROOM3-AS1 Gene Overview

**Gene Symbol:** SHROOM3-AS1  
**Location:** Chromosome 4 (4q31.3)  
**Type:** Long non-coding RNA (lncRNA)

#### Function and Characteristics
SHROOM3-AS1 is an antisense long non-coding RNA that is transcribed from the opposite strand of the SHROOM3 gene, which is involved in regulating actin cytoskeleton dynamics and cellular processes such as cell shape and differentiation. Long non-coding RNAs like SHROOM3-AS1 are known to play a crucial role in gene regulation, chromatin remodeling, and may act as molecular scaffolds in various cellular processes.

### Associated Genes
While specific additional genes directly associated with SHROOM3-AS1 may not always be explicitly mentioned in databases, lncRNAs are often implicated in regulatory networks. Given SHROOM3-AS1's relationship with SHROOM3, other potentially associated genes based on gene interaction studies could include:

- **SHROOM3**: As the most direct neighbor and functional partner.
- **Actin-related genes**: Given the role of SHROOM3 in actin dynamics.
- **Genes involved in cellular adhesion and morphogenesis**.

### Aging and Age-Related Diseases
Research indicates that lncRNAs have important roles in aging and the development of age-related diseases. Though specific studies linking SHROOM3-AS1 directly to aging or age-related diseases are limited, lncRNAs often regulate cell signaling and can influence pathways that contribute to:

- Cellular senescence.
- Age-related pathologies like neurodegenerative diseases and cardiovascular diseases.
  
In the context of SHROOM3, it may influence tissue development and maintenance, which could be relevant in age-related cellular changes.

### Drug Interactions
As of October 2023, there are no specific drugs or drug classes universally associated with SHROOM3-AS1. However, lncRNAs like SHROOM3-AS1 may indirectly affect drug efficacy and metabolism through regulation of their protein-coding counterparts and pathways. Investigating interactions with compounds that target the SHROOM3 gene or its pathways could yield relevant insights.

### Pathways and Biological Processes
SHROOM3-AS1 is implicated in several pathways:
- **Cell Migration and Adhesion**: As it relates to its neighbor SHROOM3.
- **Regulation of Cytoskeleton Dynamics**: Involved in actin filament organization.
- **Developmental Processes**: Including cranial neural crest development and morphological changes during cellular differentiation.

Additionally, research indicates involvement in pathways such as:
- **Wnt Signaling Pathway**: Important for cellular signaling and developmental biology.
- **ERK/MAPK Signaling Pathway**: Overlaps with processes of cell growth and differentiation.

### Conclusion
In conclusion, SHROOM3-AS1 is a long non-coding RNA that is integral in regulating SHROOM3 and associated with multiple signaling pathways relevant to cell dynamics and developmental processes. Research linking it to aging, disease, and drug interactions is ongoing, and further studies are necessary for a comprehensive understanding of its roles in biology and medicine.