### LINC00967 Gene Overview

**Gene Symbol:** LINC00967  
**Type:** Long Intergenic Non-Protein Coding RNA

#### 1. Associated Genes
While specific gene interactions can vary by study, LINC00967 has been associated with multiple genes in various biological contexts, including:

- **TP53:** A well-known tumor suppressor gene implicated in many cancers.
- **MYC:** An oncogene that plays a significant role in cell cycle progression, cell growth, and metabolism.
- **AURKA:** Involved in the regulation of mitosis and is often overexpressed in cancers.
- **E2F transcription factors:** These are critical regulators of the cell cycle and apoptosis.

Particular attention should be paid to pathway analyses which may connect LINC00967 to numerous other genes based on co-expression or functional associations.

#### 2. Aging and Age-Related Diseases
Research indicates that LINC00967 may play a role in aging and age-related diseases, although specific details can be less definitive due to its non-coding nature. Its expression has been linked to:

- **Cellular Senescence:** Studies have suggested that non-coding RNAs, including LINC00967, may influence the onset of cellular senescence, which is a key hallmark of aging.
- **Cancer:** Given its association with TP53 and MYC, LINC00967 may have implications in age-related cancers, contributing to tumor progression and malignancy in older populations.

Explore research databases for more specific studies relating LINC00967 to particular age-related diseases, as empirical data is continually evolving.

#### 3. Drug Interactions
Currently, there is limited direct information about specific drugs or drug classes that interact with LINC00967. However, general trends suggest that since it is implicated in cancer biology (due to its connections with oncogenes and tumor suppressors), drugs affecting pathways related to oncogenesis (such as:

- **Chemotherapy agents:** like anti-metabolites (e.g., 5-fluorouracil) or agents targeting specific pathways (e.g., kinase inhibitors).
- **Antisense oligonucleotides or siRNA:** targeted therapies might be designed to modulate its expression.)

Research is ongoing to clarify specific drug-gene interactions.

#### 4. Pathways and Biological Processes
LINC00967 is involved in several key biological processes and pathways:

- **Cell Cycle Regulation:** Given its associations, it is likely involved in regulating the cell cycle and may affect the proliferation of cancer cells.
- **Apoptosis:** Due to its connections with TP53, it may influence apoptotic pathways, particularly in response to stress signals.
- **Gene Expression Regulation:** As a long non-coding RNA, it may play roles in transcriptional regulation, potentially acting as a molecular sponge for miRNAs or interacting with chromatin-modifying complexes.

#### Final Note
As research advances, our understanding of LINC00967 and its roles in various biological contexts, particularly with regards to aging and drug interactions, will become more refined. Continuous investigation into its functional implications is necessary, with particular attention to its potential as a therapeutic target. For specialized information, consult recent literature and databases such as PubMed, GeneCards, or KEGG.