### EEF1AKMT1 Gene Overview

The **EEF1AKMT1** gene encodes a protein that exhibits **protein-lysine N-methyltransferase activity**, specifically responsible for the trimethylation of the elongation factor 1 alpha (EEF1A) at the lysine residue at position 79. This post-translational modification can influence protein function, stability, and interactions.

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### 1. Associated Genes
While the summaries do not provide a list of directly associated genes, EEF1AKMT1 may have functional links to genes involved in translational regulation, protein methylation, and other aspects of cellular metabolism. Some genes related to translational or epigenetic regulation that may show association include:

- **EEF1A1**: The gene coding for elongation factor 1 alpha 1, the primary target of the EEF1AKMT1 methyltransferase.
- **METTL3**: Involved in mRNA methylation, potentially interacting in pathways that modulate translation and RNA processing.
- **PRMTs (Protein Arginine Methyltransferases)**: Involved in protein methylation processes which could have overlapping functions with lysine methylation.

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### 2. Aging and Age-Related Diseases
**EEF1AKMT1** is implicated in processes that may be relevant to aging and age-related diseases through the modulation of protein synthesis and modification:

- **Cellular Senescence**: Altered protein methylation patterns can contribute to the senescence-associated secretory phenotype (SASP).
- **Neurodegenerative Diseases**: Abnormal protein modifications and translation processes may play a role in conditions such as Alzheimer's disease, where EEF1A and protein synthesis are affected.
- **Cancer**: Changes in methylation of proteins involved in translation could contribute to cancer cell proliferation and survival, tying EEF1AKMT1 function to oncogenic processes.

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### 3. Drug Interactions
As of the latest available data, no specific drugs or drug classes have been conclusively identified to directly interact with **EEF1AKMT1**. However, compounds that affect global methylation processes, including inhibitors of various methyltransferases (like S-adenosylmethionine-dependent methyltransferase inhibitors), could theoretically impact the activity of EEF1AKMT1.

Research into novel cancer therapies or epigenetic modifiers may yield pertinent connections in the future.

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### 4. Pathways and Biological Processes
**EEF1AKMT1** is involved in several biological processes, including:

- **Peptidyl-lysine methylation**: A key process for modifying ribosomal proteins and controlling translation fidelity and efficiency.
- **Regulation of Translation**: By modifying EEF1A, it influences translation elongation cycles.
- **Cellular Response to Stress**: Methylation events are often altered in response to cellular stress, reflecting the roles of EEF1AKMT1 in stress adaptation.
- **Epigenetic Regulation**: Although mainly recognized for post-translational modifications, the methylation status can influence gene expression patterns indirectly.

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### Summary
In summary, the **EEF1AKMT1** gene is crucial for the trimethylation of EEF1A, influencing its function in translation and cellular processes. While specific associations with aging, drugs, and other genes provide insight into its role, more research is necessary to fully elucidate its implications in health and disease.