The TP73-AS2 gene, also known as TP73 antisense RNA 2, is an intriguing element within the human genome with emerging roles, particularly in the context of cancer and other diseases. Below are the key details related to the requested points.

### 1. Associated Genes
TP73-AS2 has been linked to several other genes and pathways, including but not limited to:
- **TP73**: The gene from which TP73-AS2 is transcribed. TP73 has functions in cell cycle regulation, apoptosis, and development. 
- **CDKN1A (p21)**: This gene is a cyclin-dependent kinase inhibitor that can interact with the TP73 pathway and is often associated with cellular senescence and responses to DNA damage.
- **MDM2**: This gene encodes a negative regulator of the p53 tumor suppressor, and it can also intersect with TP73 signaling pathways.
  
Additional connections may exist with various miRNAs that influence the expression of genes involved in apoptosis and cell cycle regulation.

### 2. Aging and Age-Related Diseases
The TP73-AS2 gene has been investigated for its involvement in cellular processes related to aging:
- **Cellular Senescence**: Studies suggest that TP73-AS2 may play a role in regulating senescence pathways, which are critical in aging.
- **Cancer**: Due to its association with TP73 and involvement in apoptotic pathways, TP73-AS2 may also contribute to age-related diseases such as cancer. Abnormalities in this gene’s expression have been observed in various types of tumors.

### 3. Drug Interactions
While specific drugs targeting TP73-AS2 directly may not be well-established, the gene is involved in pathways that are modulated by:
- **Chemotherapeutics**: Since TP73 is implicated in apoptosis, drugs that activate apoptotic pathways, such as doxorubicin or cisplatin, may indirectly affect the expression or function of TP73-AS2.
- **MDM2 inhibitors**: As TP73 can interact with MDM2, drugs that inhibit MDM2 can potentially influence the activity of TP73 and by extension may have implications for TP73-AS2 expression.

### 4. Pathways and Biological Processes
TP73-AS2 is involved in several important biological pathways:
- **Apoptosis**: TP73-AS2 is believed to participate in apoptotic signaling pathways that help regulate cell death.
- **Cell Cycle Regulation**: Interactions with genes involved in cell cycle control indicate that TP73-AS2 may influence progression through critical checkpoints.
- **DNA Damage Response**: Given its relationship with TP73 and CDKN1A, TP73-AS2 may play roles in cellular responses to DNA damage, which are crucial for maintaining genomic integrity, especially relevant in the context of aging.

In summary, TP73-AS2 is tied into a complex web of cellular processes. Its roles underscore the intricacies of genetic regulation in health, aging, and disease, particularly concerning cancer biology. Research continues to unveil its implications in these areas, highlighting the relevance of non-coding RNAs in genetic frameworks.