### SNORD64 Gene Overview

**Gene Symbol:** SNORD64  
**Gene Type:** C/D box-type small nucleolar RNA (snoRNA)  
**Function:** SNORD64 is a non-coding RNA molecule involved in the modification of other RNAs, particularly ribosomal RNA (rRNA) and possibly other small nucleolar RNAs.

**Expression:** It is predominantly expressed in the brain, and its expression is absent in the brains of patients with Prader-Willi syndrome, indicating a potential role in neurological functions or diseases.

### 1. Associated Genes
While specific associations of the SNORD64 gene with other genes are not widely documented in the literature, snoRNAs often play roles in RNA modification pathways which could potentially link them to various protein-coding genes involved in ribosome biogenesis and function. 

Some examples of genes that may be connected through common pathways or functions could include:
- **RNU2 (U2 small nuclear RNA)** – Involved in spliceosome formation.
- **RPL5 (Ribosomal Protein L5)** and **RPL11 (Ribosomal Protein L11)** – Ribosomal proteins that might be influenced by snoRNA modifications.

### 2. Aging and Age-related Diseases
While there are no direct studies specifically linking SNORD64 to aging or age-related diseases, snoRNAs, in general, have been implicated in several cellular processes including cell proliferation and apoptosis. Changes in snoRNA expression profiles have been observed in various age-related diseases, including neurodegenerative diseases (such as Alzheimer's disease) and cancers.

Given SNORD64's expression in the brain, it could be speculated that it might play a role in age-related neurological decline or disorders, though more specific research would be necessary to establish a direct relationship.

### 3. Drug and Drug Classes Interaction
Currently, there are no known specific drugs or drug classes that directly interact with SNORD64 itself or its function based on publicly available data. However, since snoRNAs are involved in the processing and modification of rRNA, any drugs targeting ribosome biogenesis or RNA processing may indirectly affect the activity of snoRNAs including SNORD64. Further clinical pharmacogenomics studies could elucidate subtle interactions.

### 4. Pathways and Biological Processes
SNORD64 is primarily associated with the biological processes involving:
- **Ribosomal RNA methylation:** Small nucleolar RNAs are primarily involved in the methylation of rRNA which is crucial for ribosome biogenesis.
- **RNA processing:** Participation in the assembly and modification of ribosomal subunits.
- **Neurodevelopmental processes:** Given its expression pattern, it may be implicated in aspects of brain development and function.

### Conclusion
The SNORD64 gene represents an important component of the snoRNA family, with specific expression in the brain and possible implications in neurological health. Further studies are needed to understand its full biological functions, associations with other genes, potential impacts on aging, and interactions with drugs or pathways.