### LINC00917 Gene Overview

**Gene Symbol:** LINC00917  
**Gene Type:** Long Intergenic Non-Protein Coding RNA (lincRNA)

LINC00917 is a long non-coding RNA (lncRNA) located on chromosome 2. It is implicated in various regulatory roles, particularly in gene expression modulation.

### 1. Associated Genes

LINC00917 is primarily characterized as a long non-coding RNA, but it can be associated with other genes through various regulatory networks. While specific associations with particular protein-coding genes are not always emphasized in databases, LINC00917 may have interactions or co-expression with the following categories of genes:

- **Protein-coding genes**: Certain lncRNAs often regulate genes involved in cancer pathways, inflammation, and metabolism, indicating potential associations with genes in these categories.
- **MicroRNAs**: LINC00917 could interact with microRNAs that regulate target mRNAs in relevant biological processes.

Additional studies may be necessary to pinpoint specific genes linked to LINC00917 as associations can be context-dependent and influenced by various cellular environments.

### 2. Aging and Age-Related Diseases

LINC00917 has been implicated in studies associated with:

- **Senescence**: Research suggests that some lncRNAs, including LINC00917, may play roles in cellular senescence, a common feature of aging.
- **Cancer**: Age-related increase in cancer risk may correlate with lncRNA expression changes, including LINC00917.
- **Metabolic Disorders**: Some studies highlight lncRNAs in metabolic regulation, which can be perturbed with aging.

It's essential to note that a direct association of LINC00917 with specific aging-related conditions is still under investigation, warranting further exploration in developmental and biomedical studies.

### 3. Drug Interactions

Currently, there is limited well-characterized information regarding specific drugs or drug classes that directly interact with LINC00917. However, since lncRNAs influence gene regulatory networks, drugs targeting pathways modulated by associated protein-coding genes may indirectly influence the expression of LINC00917. 

Drugs that target key pathways associated with non-coding RNAs include:

- **Antisense oligonucleotides**: Modulators designed to inhibit lncRNA expression that could be developed for therapeutic purposes.
- **Chemotherapeutics**: Some cancer treatments may regulate lncRNA expression to impact tumor biology.

### 4. Pathways and Biological Processes

LINC00917 is involved in various biological processes, including:

- **Gene Expression Regulation**: Long non-coding RNAs function as regulators of gene transcription through various mechanisms, including chromatin remodeling and transcriptional interference.
- **Cell Cycle Regulation**: There may be involvement in signaling pathways that manage the cell cycle, influenced by environmental stressors or developmental signals.
- **Cancer Pathways**: lncRNAs, including LINC00917, are increasingly recognized as players in oncogenesis, impacting cell proliferation, apoptosis, and metastasis.

**Biological Pathways Linked to LINC00917:**
- **Cellular Senescence Pathways**
- **Oncogenic Signaling Pathways** (e.g., PI3K-Akt signaling, MAPK signaling)
- **Inflammatory Response Pathways** 

In summary, while LINC00917 is recognized primarily as a long non-coding RNA, its roles and associations are subject to ongoing research. It plays a potential role in aging and age-related diseases, but direct connections, particularly with therapeutic drugs or mechanisms, require further investigation.