The ADGRD1 gene (Adhesion G Protein-Coupled Receptor D1) is a member of the adhesion GPCR family, which are characterized by their large extracellular domains and the ability to interact with a variety of signaling proteins.

### 1. Associated Genes
While the summaries provided do not specify other genes directly associated with ADGRD1, studies involving ADGRD1 often highlight its interaction with other genes and pathways involved in cancer and glioblastoma. Some genes and proteins often noted in studies related to ADGRD1 may include:

- **GNAI1**: Involved in G-protein signaling.
- **GNAS**: Another G-protein that may be involved in signaling mechanisms.
- **PTEN**: Frequently studied in association with glioblastoma and tumorigenesis.
- **TP53**: As another tumor suppressor often functionally linked in various cancers.

### 2. Aging and Age-Related Diseases
While there’s limited specific literature directly linking ADGRD1 to aging or age-related diseases, its involvement in glioblastoma suggests a potential link to age-related cancer susceptibility, particularly given that glioblastomas are more frequently diagnosed in older adults. Research indicates that changes in GPCR signaling can affect cellular functions associated with aging, such as cellular senescence and immune response, although studies would need to clarify ADGRD1’s direct role.

### 3. Drug Interactions
Interactions with specific drugs targeting ADGRD1 have not been definitively established in major drug databases, as it is an orphan receptor and less well-characterized than other GPCRs. However, potential interactions with drug classes that impact G-protein coupled pathways (e.g., antitumor agents, signaling pathway inhibitors) might be inferred. Research into the pharmacological targeting of receptor pathways in glioblastoma therapy may expose indirect interactions.

### 4. Pathways and Biological Processes
ADGRD1 is involved in various biological processes and signaling pathways:

- **G-protein signaling pathways**: Specifically, ADGRD1 interacts with G(s)-alpha family proteins, which suggest involvement in adenylate cyclase stimulation and increased cAMP levels.
- **Cellular proliferation and migration**: Particularly in the context of tumorigenesis, highlighting potential roles in cancer biology.
- **Cell adhesion and communication**: As an adhesion GPCR, ADGRD1 is likely involved in modulating cellular interactions, crucial for maintaining tissue architecture and response to extracellular stimuli.

The understanding of ADGRD1's biological roles, especially in tumorigenesis, is still developing, and ongoing research is expected to elucidate its full range of functions and associations. Further studies may also clarify its potential as a therapeutic target in related diseases.