### SNORD114-29 Gene Summary

**Gene Symbol:** SNORD114-29

**General Description:**
SNORD114-29 is a small nucleolar RNA (snoRNA) gene that is part of the SNORD114 gene cluster. Small nucleolar RNAs play essential roles in the modification of ribosomal RNA (rRNA) and are involved in the process of snoRNA-mediated rRNA methylation.

### 1. Associated Genes
While the NCBI and UniProt summaries may not provide a comprehensive list, there are several genes that could be associated with SNORD114-29, including:

- **SNORD114 Gene Family**: This includes other snoRNA genes within the SNORD114 locus which can co-regulate or function in similar biological pathways.
- **Ribosomal Protein Genes**: Various ribosomal protein genes may interact with pathways involving this snoRNA as it modifies rRNA, potentially influencing protein synthesis.
- **C/D Box SnoRNAs**: Genes like SNORD115 may have functional interactions with SNORD114-29 due to their roles in rRNA modification.

### 2. Aging and Age-Related Diseases
The specific impact of SNORD114-29 on aging or age-related diseases remains less characterized. However, as snoRNAs play a pivotal role in ribosome biogenesis and cellular metabolism, disruptions in snoRNA function can have downstream effects on cell proliferation, differentiation, and overall homeostasis, influencing processes related to aging. 

- **Potential Link to Aging**: Alterations in snoRNA expression, including those like SNORD114-29, have been observed in various aging models and conditions related to cellular senescence, which could implicate this gene indirectly in aging-related studies.
- **Age-Related Diseases**: There may be associations with diseases like cancer or neurodegenerative disorders, where altered gene expression, including snoRNA transcripts, plays a role. Research continues in these areas.

### 3. Known Drug or Drug Interactions
As of now, there are no drug interactions specifically cited for SNORD114-29. However, understanding the broader implications of snoRNA function may help inform future research on potential compound interactions that could modulate gene expression or cellular pathways influenced by this snoRNA.

### 4. Pathways and Biological Processes
SNORD114-29 is primarily involved in the following pathways and biological processes:

- **RNA Modification**: Particularly in the methylation of rRNA, which is critical for ribosome assembly and function.
- **Ribosome Biogenesis**: Plays a fundamental role in synthesizing ribosomal RNA components.
- **Nucleolar Organization**: Being a part of the nucleolus, it is involved in the structural and functional aspects of nucleolar activity.

#### Key Pathways:
- **Eukaryotic Translation**: SNORD114-29 contributes to the proper assembly and modification of translational machinery.
- **RNA Processing**: Involvement in the maturation and processing of precursor rRNA.

### Conclusion
SNORD114-29 is an important component of the snoRNA family that contributes to cellular functions largely associated with ribosome formation and modification of rRNA. While its direct roles in aging and disease are still under investigation, its potential interactions and implications in cellular biology are notable and warrant further exploration. Future research may uncover more details regarding its interactions with other genes, pathways, and potential therapeutic implications related to age-related conditions.