### FEZF1-AS1 Gene Overview

**Gene Symbol:** FEZF1-AS1  
**Location:** Chromosome 8  
**Type:** Long non-coding RNA (lncRNA)  
**Description:** The FEZF1-AS1 gene is located adjacent to the FEZF1 gene and is known to function as an antisense long non-coding RNA. This gene is implicated in various regulatory roles in gene expression, and it has been shown to be involved in several biological processes, particularly those related to neuronal functions and development.

### 1. Associated Genes
FEZF1-AS1 has been associated with several genes, including but not limited to:
- **FEZF1**: As it is an antisense RNA, it is directly linked to this gene, which is involved in neuronal differentiation.
- **NEUROG1**: Known to play a critical role in neurogenesis.
- **GABBR2**: Associated with GABA B receptor signaling in the nervous system.
- **SYN1**: Involved in synaptic function.

### 2. Aging and Age-Related Diseases
Research into the specific role of FEZF1-AS1 in aging remains limited, but there are suggestions that it might be implicated in neurodegenerative disorders due to its involvement in neuronal differentiation and function. Increased expression of lncRNAs, including FEZF1-AS1, has been observed in various neurodegenerative diseases, such as Alzheimer's disease and other forms of dementia, indicating a potential role in aging-related pathophysiologies. 

### 3. Drug Interactions 
Currently, specific drugs or drug classes directly interacting with FEZF1-AS1 are not well-documented in the literature. However, understanding the pathways and processes influenced by this gene might implicate it in responses to neuroactive drugs or therapies aimed at neurodegenerative diseases. Drugs affecting neuronal pathways or lncRNA interactions could indirectly interact with FEZF1-AS1’s functions.

### 4. Pathways and Biological Processes
FEZF1-AS1 is involved in several biological processes, including:
- **Neuronal Development**: It is essential in promoting the expression of genes involved in neuronal differentiation.
- **Synaptic Plasticity**: Involved in the regulation of synaptic transmission and plasticity.
- **Cell Proliferation and Survival**: May impact cellular growth and longevity through paths associated with neural precursor cells.
- **Transcription Regulation**: Acts as a regulator of nearby genes, influencing their transcriptional activity.
- **Neurogenesis**: Plays a role in the differentiation of stem cells into neurons, a crucial process in both development and neuroregeneration.

### Summary
FEZF1-AS1 is a significant lncRNA with implications in neuronal development and function. While studies linking this gene to aging and neurodegenerative diseases are still emerging, its associations with key neuronal genes and pathways signify its potential role in these complex biological processes. Further research may elucidate more about its interactions with drugs and specific aging-related conditions.