### Overview of EHHADH-AS1 Gene

**Gene Symbol:** EHHADH-AS1  
**Location:** Chromosome 4  
**Type:** Long non-coding RNA (lncRNA)  

EHHADH-AS1 (EHHADH Antisense RNA 1) is a long non-coding RNA that is thought to be involved in the regulation of its sense gene, EHHADH, which encodes the enzyme enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase. This enzyme plays a critical role in fatty acid metabolism.

### Associated Genes

1. **EHHADH** - The protein-coding sense gene associated with EHHADH-AS1 involved in lipid metabolism.
2. **CPT1A** - Carnitine palmitoyltransferase 1A, another gene involved in fatty acid metabolism, could be linked through metabolic pathways.
3. **PPARGC1A** - Peroxisome proliferator-activated receptor gamma coactivator 1-alpha is involved in the regulation of genes linked to energy metabolism and mitochondrial biogenesis.
  
### Aging and Age-Related Diseases

EHHADH-AS1 has been implicated in several aging-related processes due to its role in lipid metabolism:

- **Metabolic Disorders:** Disruption in lipid metabolism is a hallmark of age-related metabolic disorders like obesity and diabetes.
- **Inflammatory Processes:** Age-associated inflammation can be partially modulated through lipid metabolism, potentially linking EHHADH-AS1 to conditions like atherosclerosis and cardiovascular diseases.
- **Cellular Senescence:** Long non-coding RNAs, including EHHADH-AS1, have been shown to have regulatory roles in cellular senescence, thus potentially influencing the aging process and age-related diseases.

### Drug Interactions

Currently, there are no specific drugs or drug classes directly associated with EHHADH-AS1. However, as it relates to lipid metabolism, compounds affecting fatty acid metabolism (e.g., fibrates or statins) may indirectly influence its expression or activity through pathways involving the EHHADH gene and metabolic processes.

### Pathways and Biological Processes

EHHADH-AS1 may be involved in various biological processes:

- **Fatty Acid Metabolism:** The lncRNA is associated with enzymes involved in the catabolism of long-chain fatty acids.
- **Lipid Biosynthesis and Storage:** Participation in pathways related to the synthesis and storage of lipids.
- **Regulatory Role in Gene Expression:** As a long non-coding RNA, it may function in transcriptional and post-transcriptional regulation of genes involved in metabolism, possibly affecting processes like gluconeogenesis and adipogenesis.

### Conclusion

EHHADH-AS1 is a long non-coding RNA with potential implications in aging, metabolic regulation, and fatty acid metabolism. While there are certain associations with other genes and biological processes, direct interactions with specific drugs remain largely unexplored. Its role in the regulation of metabolic pathways suggests it could be significant for research into metabolic disorders and aging.