### RPL35AP26 Gene Overview

**Gene Symbol:** RPL35AP26

**General Description:**
RPL35AP26 is a pseudogene located on chromosome 12, classified as part of the ribosomal protein gene family. Although it shares similarities with the RPL35A gene (which encodes for ribosomal protein L35), it is known as a pseudogene because it lacks the necessary sequences for protein-coding functionality. Pseudogenes like RPL35AP26 are generally non-functional but may still play indirect roles in cellular processes due to regulatory sequences or by interacting with other genes.

### 1. Associated Genes
While RPL35AP26 is primarily recognized as a pseudogene, it may share relationships with other ribosomal protein genes. Notable associated genes include:

- **RPL35A:** The functional paralog of RPL35AP26 that encodes ribosomal protein L35.
- **RPS (Ribosomal Protein S Genes):** Various RPS genes, as they are often co-expressed with RPL genes in the context of ribosome biogenesis.
- **RPL35:** The main gene that is functionally active and part of the ribosomal machinery.

Since the gene is a pseudogene, there may not be strong associations with many other genes outside of this context.

### 2. Aging and Age-Related Diseases
As of the latest insights, RPL35AP26 does not have direct empirical associations with aging or specific age-related diseases. However, alterations in ribosomal protein expression (in general) have been implicated in age-related processes such as:

- **Cellular senescence:** Dysregulation in ribosomal biogenesis and the associated stress responses.
- **Cancer:** Changes in ribosomal proteins are often linked to tumorigenesis and the molecular pathways of cancer development.

Further research may be needed to elucidate any specific roles RPL35AP26 could have.

### 3. Drug Interactions
Currently, there are no known drugs or drug classes specifically interacting with RPL35AP26 based on available databases. Since it is classified as a pseudogene, it does not have a direct role in pharmacological targets. However, drugs that modulate ribosome biogenesis or function might indirectly affect via pathways involving neighboring functional ribosomal genes.

### 4. Pathways and Biological Processes
RPL35AP26 does not participate directly in biological pathways due to its status as a pseudogene. However, ribosomal proteins in general, like RPL35A, are involved in several critical pathways, including:

- **Ribosome biogenesis:** The process of assembling ribosomal subunits from rRNA and ribosomal proteins.
- **Protein synthesis:** Functions indirectly through landscape interactions with ribosomal complexes.
- **Regulation of translation:** Impacting cellular processes depending on the needs of the cell, especially under stress conditions.

### Conclusion
RPL35AP26 is a pseudogene with intriguing potential implications due to its relationship with functional ribosomal proteins. The understanding of this gene's role in cellular dynamics, aging, and drug interactions remains limited and requires further research for more definitive insights.