The NT5DC3 gene, known as "5'-nucleotidase domain-containing protein 3," encodes a protein that is predicted to have 5'-nucleotidase activity and is involved in the biological process of dephosphorylation. It may also play a role in various receptor complexes. Below is a detailed elaboration on the gene and its associations:

### 1. Associated Genes
While the summaries provided do not specify additional genes associated with NT5DC3, it is typical for genes involved in similar pathways to exhibit co-expression or interaction. Some common approaches to identify associated genes include exploring gene co-expression networks, protein-protein interaction databases, and pathway analysis tools, such as:

- **NT5E**: This gene also encodes a 5'-nucleotidase and is involved in nucleotide metabolism.
- **ADA**: The adenosine deaminase gene, which is part of the purine salvage pathway.
- **ENTs (Equilibrative Nucleoside Transporters)**: Related to nucleoside transport which can also interact with metabolites affected by 5'-nucleotidases like NT5DC3.

### 2. Aging and Age-Related Diseases
Research on NT5DC3’s role in aging or age-related conditions is rather limited. However, given its involvement in nucleotide metabolism and dephosphorylation processes:

- **Aging**: Metabolism of nucleotides and modulation of adenosine levels are critical for cellular functions, which could influence aging processes. 
- **Age-related diseases**: Altered purine metabolism has been implicated in several conditions such as cardiovascular diseases, neurodegeneration, and cancer, which can be indirectly associated with NT5DC3 through its nucleotidase activity.

### 3. Drug Interactions
While specific information regarding drugs targeting NT5DC3 itself is scarce, enzymes with similar roles, such as NT5E, may have interactions with:

- **Adenosine Receptor Agonists**: In disorders where adenosine signaling is disrupted, drugs modulating this pathway could indirectly relate to NT5DC3.
- **Antimetabolites**: Such as those that influence nucleotide metabolism, which could potentially impact the function of NT5DC3.

Further investigations into pharmacogenomic databases such as DrugBank or the Connectivity Map might reveal more relevant interactions.

### 4. Pathways and Biological Processes
NT5DC3 is likely involved in several biological processes and pathways:

- **Nucleotide Metabolism**: The primary pathway since the gene encodes a 5'-nucleotidase, participating in the dephosphorylation of nucleotides to nucleosides.
- **Purine Metabolism**: This involves the synthesis and degradation of purine nucleotides, essential for energy metabolism, signal transduction, and DNA/RNA synthesis.
- **Receptor signaling pathways**: Since NT5DC3 is a part of receptor complexes, it may have roles in modifying receptor activity through its enzymatic action.

Potential pathways include those related to purine metabolism (KEGG: map00230) and processes involving other purine nucleotide regulators.

### Conclusion
Overall, while NT5DC3 plays a role in nucleotide metabolism through its 5'-nucleotidase activity, its wider implications for aging, drug interactions, and specific pathways require more targeted studies. Future research might help to illuminate its full biological significance and potential as a therapeutic target in age-related diseases and metabolic disorders.