### RNU6-987P Gene Overview

**Gene Symbol:** RNU6-987P

**Gene Type:** RNU6-987P is classified as a small nucleolar RNA (snoRNA), specifically a member of the U6 family of snoRNAs, which are involved in the biogenesis of small nuclear ribonucleoproteins (snRNPs) and play crucial roles in RNA splicing.

#### 1. Associated Genes
While specific associations with other genes are often context-dependent and can vary by research studies, RNU6-987P's primary function relates to RNA processing. Other small nucleolar RNAs in the U6 family may interact with spliceosomal components. Additionally, snoRNAs can often have interactions with genes involved in RNA modification or processing. However, specific gene associations in public databases like NCBI or UniProt may not indicate direct connections; instead, RNU6-987P likely associates with the machinery of pre-mRNA splicing (e.g., genes coding for splicing factors).

#### 2. Aging and Age-Related Diseases
Current literature on RNU6-987P specifically in the context of aging or age-related diseases has not been significantly documented. However, the J. Biol. Chem and other journals have noted that dysregulation of small nucleolar RNAs can contribute to age-associated disorders due to their role in pre-mRNA splicing and ribosome biogenesis. Changes in expression levels of snoRNAs, including members of the U6 family, may affect cellular aging processes and have implications for conditions such as cancer or neurodegenerative diseases.

#### 3. Drug Interactions
To date, there are no specific drug interactions or drug classes that have been clearly documented to directly interact with RNU6-987P. However, it is pertinent to note that drugs affecting RNA biology (such as those that inhibit transcription, RNA processing, and splicing modulators) could influence the activity of small RNAs. Future research might elucidate potential interactions between pharmacological agents and snoRNA functionality.

#### 4. Pathways and Biological Processes
RNU6-987P is primarily involved in the following biological processes:

- **RNA Splicing:** The U6 snoRNA family, including RNU6-987P, plays a critical role in the splicing of pre-mRNA in the nucleus. This is essential for generating mature mRNA.
- **Pre-mRNA Processing:** Small nucleolar RNAs are known to assist in the processing and modification of pre-mRNA, leading to the generation of mature mRNA sequences necessary for protein synthesis.
- **Ribosome Biogenesis:** Though more indirect, the processing and maturation of rRNA can be influenced by snoRNAs, impacting ribosome assembly and function.

Additionally, small nucleolar RNAs, including those in the U6 family, may be involved in broader regulatory networks that control gene expression, particularly regarding splicing fidelity and efficiency.

### Conclusion
The RNU6-987P gene represents an important component of the cellular machinery involved in gene expression regulation through RNA processing. While direct associations with certain pathways, diseases, and therapeutic interactions require further exploration, its role as a small nucleolar RNA places it in critical processes relevant to cellular function and RNA biology.