### Overview of ENTPD1-AS1

**Gene Symbol:** ENTPD1-AS1

ENTPD1-AS1 is an antisense RNA gene that is located adjacent to the ENTPD1 gene, which encodes ecto-nucleotide triphosphate diphosphohydrolase-1. The function of the ENTPD1-AS1 gene is still being elucidated, but it is a non-coding RNA that may play regulatory roles in gene expression processes.

### 1. Associated Genes
While specific associations have not been fully elucidated, ENTPD1-AS1 is closely situated to the ENTPD1 gene, which is involved in purine metabolism and has implications in cell signaling pathways. Other potential associated genes in related contexts may include:
- **ENTPD1 (ectonucleotide triphosphate diphosphohydrolase 1)**: The coding gene adjacent to ENTPD1-AS1.
- **Other ncRNA genes**: Depending on specific regulatory frameworks or pathways being studied, other long non-coding RNAs (lncRNAs) that regulate or interact with ENTPD1 may also indirectly associate with ENTPD1-AS1.

### 2. Aging and Age-Related Diseases
Research implicating ENTPD1-AS1 in aging or age-related diseases is still emerging. However, the primary gene it is associated with, ENTPD1, has been studied in the context of:
- **Cancer**: Abnormal expression of ENTPD1 has been linked to various cancers, which are often associated with aging.
- **Regulatory roles in inflammatory processes**: As aging is associated with chronic inflammation, genes influencing inflammation pathways may indirectly relate.
  
Further studies are needed to clarify any direct associations of ENTPD1-AS1 with specific aging-related pathways or diseases.

### 3. Drug Interactions
As of the current knowledge base (up to October 2023), specific drugs that interact directly with the ENTPD1-AS1 gene are not well documented. However, potential areas of research include:
- **Anticancer drugs**: As ENTPD1 is associated with cancer mechanisms, drugs targeting purine metabolism or those used in cancer therapy may warrant investigation concerning their effects on ENTPD1-AS1 expression indirectly.
- **Immunotherapeutics**: Since altered expression of genes such as ENTPD1 can affect immune responses, drugs modulating the immune system may also influence pathways regulated by ENTPD1-AS1.

### 4. Pathways and Biological Processes
ENTPD1-AS1 is believed to be involved in:
- **Regulation of Gene Expression**: As an antisense RNA, ENTPD1-AS1 may play a role in regulating the transcription of the ENTPD1 gene and possibly other nearby genes.
- **Nucleotide Metabolism**: Given the relationship with ENTPD1, there may be implications in pathways that involve nucleotide metabolism.
- **Cellular Signaling**: It could play a role in modulating pathways that involve ATP metabolism and signaling, as well as influencing processes like apoptosis and immune response.

### Conclusion
Although significant insights have been garnered from the characterization of ENTPD1-AS1, the precise functional implications, especially those relating to aging and drug interactions, remain active fields of research. Further studies will be crucial to delineate its role within biological systems and its potential clinical significance.