**WDR86-AS1 Gene Overview:**

- **Gene Symbol:** WDR86-AS1
- **Location:** The WDR86-AS1 gene is classified as a long non-coding RNA (lncRNA) and is transcribed from the opposite strand of the WDR86 gene. The WDR86 gene itself encodes a WD repeat domain 86 protein that is involved in several cellular processes.

### 1. Associated Genes:
While specific associations can vary based on context (e.g., disease conditions, cellular pathways), here are some genes that have been observed in relation to WDR86-AS1, particularly in studies focusing on its interactions:
- **WDR86:** The primary protein-coding gene associated with WDR86-AS1; it likely relates to transcriptional regulation.
- **NEAT1:** This lncRNA, like WDR86-AS1, is involved in nuclear speckle formation and has implications in cellular stress responses.
- Other intergenic and gene-regulatory elements in proximity may also influence the expression or functional outcomes of WDR86-AS1, although specific genes might vary with different studies.

### 2. Aging and Age-related Diseases:
WDR86-AS1 has been implicated in several cellular processes, which could be related to aging and age-related diseases. Some known associations include:
- **Cellular Stress Response:** As aging involves accumulative stress at the cellular level, lncRNAs like WDR86-AS1 may play a role in mediating responses to oxidative stress.
- **Cancer:** Aberrant expression of WDR86-AS1 has been observed in various cancers, suggesting a potential role in tumorigenesis and progression. Cancer is often associated with aging, and the gene may be involved in age-related cancer susceptibility.

### 3. Drug Interactions:
As of my last data update in October 2023, specific drug interactions with WDR86-AS1 have not been prominently reported in literature. However, given that it may be involved in pathways related to cancer and cellular stress responses, compounds targeting those pathways may indirectly interact. Some potential drug classes that could influence pathways involving WDR86-AS1 are:
- **Chemotherapeutics:** Drugs like doxorubicin or cisplatin, which target cancer pathways, could indirectly affect WDR86-AS1 expression levels in cancer settings.
- **Antioxidants:** Compounds aiming to reduce oxidative stress may also influence the function of lncRNAs involved in stress responses, including WDR86-AS1.

### 4. Pathways and Biological Processes:
WDR86-AS1 is involved in various biological processes and pathways:
- **Gene Regulation:** As a long non-coding RNA, it may function in chromatin remodeling and transcriptional regulation of neighboring genes, particularly those involved in stress responses or metabolic processes.
- **Cellular Responses to Stress:** Its expression can be modulated under conditions of cellular stress, indicating a potential role in cell survival and adaptation mechanisms.
- **Cancer Pathways:** The gene is associated with oncogenic pathways, particularly in the context of regulation of gene expression pertinent to cellular proliferation and apoptosis, making it a subject of interest in cancer research.

### Summary
WDR86-AS1 reflects the complexities of gene regulation through non-coding RNAs, with potential implications in aging, cellular stress responses, and cancer. However, further investigation into its specific functions and interactions may provide more insight into its roles and potential therapeutic targets.