### RNU2-72P Gene Summary

**Gene Symbol:** RNU2-72P  
**Gene Type:** Small nucleolar RNA (snoRNA) gene and a pseudogene  
**Location:** This gene is located on chromosome 17 in the human genome.

RNU2-72P is classified as a non-coding RNA, specifically a small nucleolar RNA (snoRNA), that is involved in guiding the chemical modification of other RNAs, particularly rRNAs. As a pseudogene, it is a remnant of a functional gene that has lost its protein-coding ability.

### 1. Associated Genes

While RNU2-72P itself does not have a direct association with many genes due to its pseudogene status, it might be linked to other snoRNA genes, particularly those involved in rRNA processing, due to their similar functions. Some snoRNA genes that may share pathways or regulatory mechanisms include:

- RNU2-61 (another snoRNA)
- RNU3 (a family of snoRNAs involved in RNA modification)

### 2. Aging and Age-Related Diseases

There is limited specific literature connecting RNU2-72P directly with aging or age-related diseases. However, as a snoRNA, it may play roles in the maintenance of ribosome biogenesis, which is essential for cellular function. Disruptions in RNA processing have been linked to various age-related diseases such as cancer and neurodegenerative disorders, but direct evidence for RNU2-72P's involvement in these processes is lacking.

### 3. Drug Interactions

Currently, there are no known drugs or drug classes specifically linked to interactions with RNU2-72P. Since it is a pseudogene and does not encode proteins, it's less likely to be a direct target for pharmacological intervention compared to protein-coding genes.

### 4. Pathways and Biological Processes

RNU2-72P primarily plays a role in nucleolar processing related to the assembly and modification of ribosomal RNA, contributing to the following pathways and biological processes:

- **Ribosome Biogenesis:** snoRNAs guide methylation and pseudouridylation of rRNAs, contributing to the structural integrity of ribosomes.
- **RNA Modification:** Influences rRNA modifications that are critical for efficient protein synthesis.
- **Nuclear Organization:** Involved in the dynamics of nucleolus organization and function.

Although RNU2-72P itself does not play an active role in encoding proteins or enzymes directly, the pathways it influences through snoRNA activities are essential for overall cellular health and function.

### Conclusion

RNU2-72P, as a pseudogene and snoRNA, is part of a family that maintains RNA quality and function. Its roles indirectly affect many cellular processes, but more specific associations with known diseases or pharmacological interactions remain largely under exploration. Further research may clarify its contributions in a biological context, particularly in relation to aging and disease.