### RPS28P8 Gene Overview

**Gene Symbol:** RPS28P8

**Description:** RPS28P8 is a pseudogene located on the human genome. Pseudogenes are segments of DNA that resemble functional genes but are non-functional. They arise from gene duplication or retrotransposition and are often not transcribed into functional mRNA. RPS28P8 is associated with the ribosomal protein family, but as a pseudogene, it does not produce a protein product.

### 1. Associated Genes

While RPS28P8 is primarily identified as a pseudogene associated with ribosomal protein genes, specific associations with other genes are not explicitly detailed in the available summaries. However, genes related to other ribosomal protein families may be indirectly connected. These could include:

- **RPS28:** The functional counterpart of RPS28P8, part of the ribosomal protein family, playing critical roles in protein synthesis.
- **RPL or RPS family genes:** Other ribosomal proteins that are critical for the assembly of ribosomes and translation.

### 2. Aging and Age-Related Diseases

Currently, there are no specific studies or data linking RPS28P8 directly to aging or age-related diseases. Generally, pseudogenes like RPS28P8 might have regulatory functions or play roles in the expression of related active genes during various physiological conditions, including aging. However, specialized studies focusing on RPS28P8 in the context of aging are lacking.

### 3. Drug Interactions

As RPS28P8 is classified as a pseudogene and does not produce a functional protein, there are no known drug interactions directly associated with it. Drug interactions typically involve functional genes whose protein products are targets for therapeutic agents.

### 4. Pathways and Biological Processes

- **Ribosome Biogenesis:** While RPS28P8 itself does not directly contribute to ribosome assembly, it is related to the pathway of ribosomal protein synthesis due to its association with genes encoding functional ribosomal proteins.
- **Protein Synthesis:** Since it belongs to the family of ribosomal proteins, it is likely related to the overall process of translating mRNA into polypeptides; however, this is an indirect relationship, given that RPS28P8 is a pseudogene.

In summary, RPS28P8, as a pseudogene, serves as a reminder of the complexity of gene evolution and regulation in humans. While it is grouped with ribosomal proteins, its function and implications in health and disease are not fully understood, and it represents an area of potential research.