### DLGAP1-AS4 Gene Overview

**Gene Symbol**: DLGAP1-AS4  
**Description**: DLGAP1-AS4 (DLGAP1 antisense RNA 4) is a long non-codingRNA (lncRNA) that plays a role in various biological processes.

### 1. Associated Genes

DLGAP1-AS4 has been associated with various genes, particularly those in the context of neural development and synaptic function. Some of the notable genes that show interaction or association with DLGAP1-AS4 include:

- **DLGAP1**: The protein-coding gene that encodes a member of the Discs Large (DLG) family of proteins, which is involved in synaptic signaling.
- **DLG4** (also known as PSD-95): A synaptic protein involved in organizing synaptic signaling complexes.
- **Other DLG family members** such as DLG2 (SAP97) and DLG3 (SAP102) which also play roles in synaptic structure and function.

### 2. Aging and Age-Related Diseases

While specific studies directly linking DLGAP1-AS4 to aging are limited, lncRNAs have been increasingly implicated in aging and age-related diseases. Some relevant points include:

- **Neurodegenerative Diseases**: As DLGAP1-AS4 is associated with genes linked to synaptic function, abnormalities in its expression could potentially relate to age-related neurodegenerative diseases such as Alzheimer's disease.
- **Cellular Senescence**: Some lncRNAs have been found to regulate pathways involved in cellular senescence, although specific studies directly highlighting DLGAP1-AS4 in this context may not be available.

### 3. Drug Interactions

Currently, specific drugs that directly interact with DLGAP1-AS4 are not well-documented. However, it is recognized that lncRNAs can play roles in mediating responses to therapies, especially in cancer treatment and neurological disorders. Further research could reveal significant interactions.

### 4. Pathways and Biological Processes

DLGAP1-AS4 is involved in various pathways and biological processes, including:

- **Cellular Communication**: As it is associated with synaptic proteins, it is likely involved in pathways related to synaptic transmission and plasticity.
- **Gene Regulation**: lncRNAs often participate in regulatory networks, including chromatin remodeling and modulation of transcriptional activity.
- **Developmental Processes**: It may play a role in brain development and differentiation of neuronal cells.

### Summary

DLGAP1-AS4 is an important long non-coding RNA associated with genes involved in synaptic function and development. While more research is needed to fully understand its roles in aging and drug interactions, its connections to neurobiology suggest it could be significant in the context of neurological health and disease.