### SNORD114-13 Gene Overview

**Gene Symbol**: SNORD114-13

**Gene Type**: SNORD114-13 is classified as a small nucleolar RNA (snoRNA), specifically a member of the C/D box snoRNA family, which are primarily involved in the modification of rRNA.

### 1. Associated Genes

SNORD114-13 is primarily associated with the following gene(s):

- **SNORD114** (itself is a part of a larger SNORD114 cluster)
- **MGP**: Matrix Gla protein, which has implications in vascular calcification.
- **MIR29B**: A member of the microRNA family implicated in various regulatory functions.

Although specific associations with other genes are limited, there may be indirect relationships with genes involved in ribosome biogenesis and RNA modifications due to its role as a snoRNA.

### 2. Aging and Age-Related Diseases

Currently, there is limited direct evidence linking SNORD114-13 to aging or age-related diseases. However, given its role in rRNA modification, aberrations in snoRNA functions, including those in the SNORD114 family, have been speculated to contribute to age-related declines in cellular function, specifically in stem cell maintenance and differentiation. Further research is needed to establish any direct correlation to specific age-related diseases, for instance, neurological diseases or cancer, which often involve disruptions in RNA processing.

### 3. Drug Interaction

As of now, there are no specific drugs or drug classes universally recognized to interact directly with the SNORD114-13 gene. However, certain general classes of drugs that target RNA processes may indirectly influence the expression or activity of snoRNAs, including:

- **Antisense Oligonucleotides**: Used for various genetic disorders by modulating RNA processing.
- **Small Molecule Inhibitors**: Targeting various RNA synthesis processes might also affect snoRNA functionality.

### 4. Pathways and Biological Processes

SNORD114-13 is involved in:

- **Ribosome Biogenesis**: As a snoRNA, it helps in the methylation and processing of rRNA, which is crucial for the formation of functional ribosomes.
- **RNA Modification Processes**: Plays a significant role in guiding the chemical modifications of rRNA, which is vital for proper ribosomal function and protein synthesis.
- **Cellular Processes**: Alterations in snoRNA expression, including SNORD114-13, have been associated with processes such as apoptosis, proliferation, and differentiation under certain conditions.

Further research and specific studies may shed light on additional pathways and processes influenced by SNORD114-13 and its larger gene family. 

### Summary

SNORD114-13 is a small nucleolar RNA with an essential role in rRNA modification and function. While its direct connection to aging, age-related diseases, and drug interactions remains underexplored, its involvement in fundamental cellular processes like ribosome biogenesis is well established. Further research could elucidate its broader implications in health and disease.