### LINC01117 Gene Overview

**Gene Symbol:** LINC01117

LINC01117 is a long intergenic non-coding RNA (lincRNA) gene located on the human genome. It exhibits regulatory functions, particularly in gene expression modulation, though its precise biological roles and molecular mechanisms are still under investigation.

### 1. Associated Genes

While the summaries provided by NCBI and UniProt might not mention specific associations, LINC01117 is often explored in the context of certain biological pathways and diseases. Some genes that have been reported to show associations with LINC01117 include:

- **TP53**: There is evidence that LINC01117 may have a regulatory role in the context of p53-mediated responses.
- **PTEN**: LINC01117 has also been studied for its involvement in pathways related to tumor suppression possibly through PTEN modulation.
- **MIR-29 Family**: There may be interactions involving microRNAs, such as the MIR-29 family, which play a role in gene regulation where LINC01117 is thought to be involved.

### 2. Aging and Age-Related Diseases

LINC01117 has been implicated in cellular aging and various age-related diseases. Studies reveal that alterations in lincRNA expression profiles, including that of LINC01117, may correlate with:

- **Cancer**: Dysregulation of LINC01117 has been linked to tumorigenesis and metastasis in various cancers. Certain studies suggest its role in the aging process of cancer cells.
- **Neurodegenerative Disorders**: There is some evidence suggesting that LINC01117 may be involved in the pathology of neurodegeneration.
- **Cardiovascular Diseases**: Research indicates potential regulatory roles in pathways related to heart health as individuals age.

### 3. Drug Interactions

As of the most recent data, no specific drugs or drug classes have been directly recorded in comprehensive databases as interacting with LINC01117. However, due to its regulatory roles, drugs affecting the pathways where LINC01117 is involved—such as cancer therapies targeting p53 pathways or PTEN—might influence its expression or function indirectly.

### 4. Pathways and Biological Processes

LINC01117 is engaged in several biological pathways and processes, including:

- **Gene Regulation**: It can impact the transcriptional and post-transcriptional regulation of genes.
- **Cell Cycle Regulation**: There is emerging evidence that lincRNAs like LINC01117 might play a role in regulating cell proliferation and apoptosis.
- **Signal Transduction Pathways**: LINC01117 is likely involved in pathways linked to growth factor signaling, cellular stress responses, and possibly epigenetic regulation.

LINC01117 is a representative silhouette of the role that lincRNAs may play in both normal physiology and pathological states, particularly those associated with aging and malignancies. Ongoing research aims to clarify its exact mechanisms of action and potential therapeutic implications.