**ANKRD61 Gene Overview**

**Gene Symbol:** ANKRD61  
**Location:** Nucleoplasm  
**Gene Type:** Protein-coding

**Protein Summary:** 
ANKRD61 is a gene that encodes a protein containing ankyrin repeats, which are known to mediate protein-protein interactions. It is involved in various cellular processes due to its function in the nucleoplasm.

### 1. Associated Genes
While specific genes directly associated with ANKRD61 might not always be detailed in generic summaries, various literature and databases suggest potential interactions. Some genes that have been studied in relation with ANKRD61 include:

- **TP53:** The tumor protein p53, which is a crucial regulator of the cell cycle and a key player in tumor suppression.
- **MDM2:** Mouse double minute 2 homolog, which is known to regulate p53 activity and degradation.
- **GSK3B:** Glycogen synthase kinase 3 beta, which is involved in various signaling pathways and may influence processes like cell division and cancer progression.

### 2. Aging and Age-Related Diseases
Research has suggested that ANKRD61 may have implications in aging or age-related diseases, although specific connections might still be under investigation. Some potential associations include:

- **Cellular Senescence:** Proteins with ankyrin repeats are often implicated in cellular stress responses and may play roles in cellular senescence, which is a process that can contribute to aging.
- **Neurodegenerative Diseases:** Some studies have hinted that proteins involved in nucleoplasmic activities may play roles in neurodegenerative conditions; however, direct connections to ANKRD61 specifically remain to be elucidated.

### 3. Drug Interactions
As of the latest information available up to October 2023, there are no specific drugs or drug classes that have been explicitly linked to ANKRD61 in standard databases. However, as the protein may interact with pathways related to stress response, tumor suppression, or cell cycle regulation, certain chemotherapeutic agents or compounds targeting these pathways could potentially have indirect interactions.

### 4. Pathways and Biological Processes
ANKRD61 is involved in several biological processes and pathways, including but not limited to:

- **Cell Cycle Regulation:** The protein may interact with other cell cycle regulators, influencing transition phases and checkpoints.
- **Response to Stress:** Proteins with ankyrin repeats often play roles in cellular stress response, including responses to oxidative stress or inflammatory signals.
- **Signal Transduction Pathways:** ANKRD61 may interact with various signaling pathways, potentially including those involved in apoptosis and proliferation.

### Conclusion
ANKRD61 is a significant gene within the context of protein interactions and cellular processes, with connections to aging, cellular regulation, and potentially disease mechanisms. Further research may help clarify its specific roles and relationships, particularly in the context of health and disease. The understanding of its interactions and implications in pathways can have potential translational significance in therapy development.