### RNA5SP358 Gene Summary

**Gene Symbol:** RNA5SP358

**General Description:** 
RNA5SP358 is a gene that encodes a member of the small nucleolar RNA (snoRNA) family, which are essential for the processing and modification of ribosomal RNA (rRNA). This gene is classified as a non-coding RNA, primarily involved in the maturation and modification of rRNA in the nucleolus. It belongs to the class of small nucleolar RNAs that utilize guide sequences to direct the methylation and pseudouridylation of target rRNAs.

### 1. Associated Genes
RNA5SP358 may be associated with other small nucleolar RNAs and genes involved in RNA processing and ribosome biogenesis. However, specific gene associations need to be derived from pathway analyses or co-expression studies, as they are not typically mentioned in general summaries. Known genes in the context of snoRNAs may include:

- **RNU2:** Another small nuclear RNA involved in RNA processing.
- **RPL (Ribosomal Protein) Genes:** Various ribosomal protein genes may be associated with genes like RNA5SP358 due to their common role in ribosome assembly.

### 2. Aging and Age-Related Diseases
While specific literature on RNA5SP358 directly related to aging or age-related diseases might be limited, small nucleolar RNAs, in general, have been implicated in the regulation of cellular processes that could impact aging, such as:

- **Cellular Senescence:** snoRNAs play a role in the biogenesis of ribosomes and thus could be connected to cellular growth and division, which are critical in aging.
- **Age-Related Disorders:** Dysregulation of snoRNAs can affect cellular functions, potentially leading to diseases such as cancer, which is prevalent in aging populations.

### 3. Drug Interactions
Currently, there may not be direct drug interactions specifically tied to RNA5SP358 identified in databases such as NCBI or UniProt. However, small nucleolar RNAs might have broader implications in drug metabolism or the response to therapies targeting the ribosomal machinery or modifying RNA processes:

- **Potential Drug Classes:** This could include **antineoplastics** or **antiviral agents** that alter RNA synthesis or utilization.

### 4. Pathways and Biological Processes
RNA5SP358 is primarily involved in the following biological processes:

- **Ribosome Biogenesis:** RNA5SP358 is implicated in the synthesis and assembly of ribosomes by modifying rRNA.
- **rRNA Methylation and Pseudouridylation:** As a snoRNA, it guides the modification of rRNA, crucial for ribosome function.
- **Nuclear RNA Processing:** Plays a role in the broader context of the processing of various RNA molecules within the nucleus.

### Conclusion
RNA5SP358 is an important component of the cellular machinery responsible for ribosomal function and RNA processing. While its direct involvement in aging and drug interactions is less documented, it remains a significant player in the cellular processes crucial for maintaining healthy cellular function over time. Further studies may elucidate more specific roles and interactions in the context of various diseases and aging.