### FAM91A1 Gene Overview

The **FAM91A1** gene encodes a protein that has a crucial role in intracellular protein transport and vesicle tethering to the Golgi apparatus. It is part of the WDR11 complex and works in conjunction with TBC1D23 to aid in the golgin-mediated capture of vesicles emanating from AP-1.

### 1. Associated Genes

While the summaries provided mention **WDR11** and **TBC1D23**, FAM91A1 may also show associations with several other genes, typically those involved in Golgi function and vesicular transport, such as:

- **AP1S1**: Component of the AP-1 clathrin-AP complex.
- **GOLGA2**: Involved in Golgi organization.
- **RAB proteins** (various members): Small GTPases that are key players in vesicular transport.
- **SNARE proteins**: Various members involved in membrane fusion processes.

### 2. Aging or Age-related Diseases

Currently, specific associations between **FAM91A1** and aging or age-related diseases may not be extensively characterized in the literature available up until October 2023. However, given its role in vesicle traffic and intracellular transport, alterations or dysfunctions in this gene might be implicated in:

- **Neurodegenerative diseases**: Such as Alzheimer’s or Parkinson’s, where intracellular transport processes are known to be disrupted.
- **Metabolic disorders**: Aging often affects metabolic pathways; thus, FAM91A1 could be indirectly related to age-associated metabolic syndromes.

### 3. Drug Interactions

As of the last update in October 2023, there are no specific drugs or drug classes explicitly listed as interacting with **FAM91A1**. However, drugs that target pathways of vesicular trafficking or Golgi functions could indirectly affect the processes involving FAM91A1. Further research may reveal medications that influence proteins working in similar pathways.

### 4. Pathways and Biological Processes

The **FAM91A1** gene is involved in several biological processes and pathways including:

- **Intracellular vesicle transport**: Essential for the movement of proteins and other molecules between organelles.
- **Vesicle-mediated transport**: Particularly its role in vesicle tethering to the Golgi network.
- **Protein transport**: Involvement in the sorting and modification of proteins as they move towards their destinations.
- **Golgi organization**: Integral to maintaining the structure and function of the Golgi apparatus.

In summary, the FAM91A1 gene plays significant roles in intracellular transport mechanisms, particularly in vesicle tethering to the Golgi, while its broader relationships with aging and disease processes warrant further investigation.