### FAM110C Gene Overview

**Gene Symbol:** FAM110C  
**Function:** FAM110C encodes a protein that has been shown to enable alpha-tubulin binding activity, contributing to microtubule organization. It positively regulates cell migration and protein kinase B (AKT) signaling, and is involved in the assembly of cell projections. The protein is predominantly located in the cell cortex and may play roles in cell spreading, particularly within epithelial cells, potentially influencing processes that involve AKT1 signaling pathways.

### 1. Associated Genes
FAM110C is known to have interactions with several other genes that may include, but are not limited to: 
- **AKT1**: Since FAM110C positively regulates AKT1 signaling, this gene is particularly relevant.
- **MAPK pathways**: Genes involved in MAPK pathways might also be associated, given the involvement of FAM110C in cell signaling.

Additional interactions might exist, especially in the context of cell migration and cytoskeletal organization, but specific genes may not be detailed in the summary provided.

### 2. Aging and Age-Related Diseases
Research on FAM110C in relation to aging or age-related diseases is limited; however, its role in cell migration and possibly in oncogenic processes could imply a connection. Aberrations in cell migration and cytoskeletal dynamics are implicated in cancer metastasis, which often increases with age. Therefore, changes in FAM110C expression or function may play a role in age-related changes in tissue architecture or function, particularly in epithelial tissues.

### 3. Drug Interactions
While specific drugs directly interacting with FAM110C are not well-documented, given its role in cell signaling pathways such as the AKT pathway:
- **PI3K/AKT inhibitors**: These drugs may influence pathways in which FAM110C is a participant, even if not directly targeting FAM110C itself.
- Any drug targeting microtubule dynamics (e.g., **taxanes** or **vinca alkaloids**) could indirectly affect FAM110C function, given its involvement in microtubule organization.

### 4. Pathways and Biological Processes
FAM110C is involved in several critical biological processes:
- **Positive regulation of cell migration**: This is vital for wound healing, immune responses, and cancer metastasis.
- **Positively regulates protein kinase B signaling**: Plays an essential role in various cellular processes including metabolism, growth, survival, and proliferation.
- **Regulation of cell projection assembly**: Important for cellular architecture and signaling.

Additionally, pathways likely affected by FAM110C include:
- **Cell migration pathways**, including those regulated by growth factors.
- **Microtubule dynamics and organization pathways** associated with cytoskeletal changes.
- **Signal transduction pathways** such as the phosphoinositide 3-kinase (PI3K)/AKT pathway, which is crucial for many processes ranging from metabolism to apoptosis.

In summary, while FAM110C has established roles in cell migration and signaling, further research is needed to elucidate its full spectrum of interactions and implications in aging and disease.