### WNT5A Gene Overview
The WNT5A gene encodes a member of the WNT gene family, known for their important roles in cell signaling, particularly during embryonic development and oncogenesis. The protein plays a critical role in the non-canonical WNT signaling pathways and interacts with the frizzled receptor family and ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) to modulate downstream effects such as cell migration and proliferation.

### 1. Associated Genes
WNT5A interacts with several other genes and signaling pathways, including:
- **FZD4**: A member of the frizzled receptor family that activates beta-catenin signaling in presence of WNT5A.
- **ROR2**: Inhibits the canonical pathway in response to WNT5A.
- **GSK3B**: Glycogen synthase kinase 3 beta, involved in beta-catenin degradation mechanism in the context of WNT signaling.
- **CTNNB1 (Beta-catenin)**: Involved in the canonical WNT signaling pathway where WNT5A can stabilize or inhibit its activity depending on its receptor context.

### 2. Aging and Age-Related Diseases
While specific studies directly linking WNT5A to aging are limited, there are several associations:
- **Oncogenesis**: WNT5A's role in regulating tumor growth suggests a potential role in age-related cancers, as alterations in WNT signaling pathways are often implicated in cancer development during aging.
- **Tissue Regeneration and Repair**: WNT5A has been shown to be important in processes involving tissue repair, which may decline with age.
- **Bone Development**: WNT signaling, influenced by WNT5A, plays a crucial part in bone remodeling, and dysregulation may contribute to age-related bone diseases such as osteoporosis.

### 3. Known Drug Interactions
Currently, there are no specific drugs implicated directly in the modulation of WNT5A activity. However, drugs targeting WNT signaling pathways or the receptors associated with WNT5A (like Frizzled and ROR2) are of significant interest in oncological settings. Drug classes include:
- **Kinase inhibitors**: Such as those targeting GSK3, may affect the degradation pathways of beta-catenin.
- **WNT Pathway Modulators**: Compounds aimed at either activating or inhibiting the downstream effects of WNT signaling pathways are under investigation.

### 4. Pathways and Biological Processes
WNT5A is involved in several key biological pathways and processes, including:
- **WNT Signaling Pathway**: Activates both canonical (beta-catenin dependent) and non-canonical pathways, leading to various cellular outcomes.
- **Cell Migration and Motility**: Implicated in processes such as cancer metastasis and embryonic development.
- **Chondrogenesis**: Plays a role in the differentiation of chondrocytes and in the development of cartilage.
- **Embryonic Development**: Essential for the extension of the anterior-posterior axis and limb formation during early stages of development.
- **Tumor Suppression**: Through inhibition of proliferation and induction of apoptosis in certain carcinoma types.

### Summary
WNT5A is a key player in both developmental and pathological processes. Its dual roles in activation and inhibition of WNT signaling, along with involvement in oncogenesis and embryogenesis, highlight its significance in both normal physiology and disease states. Further research is necessary to elucidate the full spectrum of its interactions, particularly concerning age-related implications and therapeutic potentials.