### Overview of the YWHAEP4 Gene

**Gene Symbol:** YWHAEP4  
**Function:** YWHAEP4 (14-3-3 epsilon proline-rich protein 4) is part of the 14-3-3 protein family, characterized by their ability to bind to phosphoserine-containing proteins, which is crucial in numerous signaling pathways and cellular processes, including cell cycle regulation, apoptosis, and others. 

### 1. Associated Genes
YWHAEP4 is known to be associated with several other genes that may be functionally related, including:
- **YWHAE:** Another member of the 14-3-3 protein family.
- **YWHAZ:** A closely related gene in the 14-3-3 family.
- **YWHAG:** Yet another gene related to cellular signaling and functions.
- **SGK1:** Serum/glucocorticoid-regulated kinase, which may interact with YWHAEP4 in signaling pathways.
- **AKT1:** Protein kinase B, involved in pathways related to growth and survival that could intersect with the functions of YWHAEP4.

### 2. Aging and Age-Related Diseases
Research has indicated that the 14-3-3 protein family, including YWHAEP4, plays roles in cellular stress responses, signaling pathways, and apoptosis, which are critical in aging and age-related diseases. 
- **Neurodegenerative Diseases:** Alterations in 14-3-3 proteins have been associated with diseases such as Alzheimer's and Parkinson's, suggesting that YWHAEP4 may also contribute to these processes by influencing neuronal survival and protein aggregation responses.
- **Cancer:** Deregulation of YWHAEP4 has been linked to various cancers, indicating its potential role in tumorigenesis and cellular aging.

### 3. Drug Interactions
Currently, there are no specific drugs or drug classes directly linked to YWHAEP4 in the literature. However, due to its role in numerous signaling pathways and cellular processes, it may be indirectly influenced by:
- **Antineoplastic drugs:** As it is associated with cancer biology.
- **Anti-inflammatory agents:** Given the role of 14-3-3 proteins in stress responses and inflammation.

### 4. Pathways and Biological Processes
YWHAEP4 is involved in several important biological processes, including:
- **Cell Cycle Regulation:** 14-3-3 proteins modulate the activity of various cell cycle regulators.
- **Apoptosis:** YWHAEP4 can influence apoptotic pathways by interacting with pro-apoptotic and anti-apoptotic factors.
- **Signal Transduction:** It is an essential part of many signaling pathways, including those involving phosphorylated proteins.
- **Metabolism Regulation:** It plays a role in glucose and energy metabolism.

In summary, while information regarding YWHAEP4 is currently limited, ongoing studies surrounding the 14-3-3 protein family continue to unravel its significance in health and disease, particularly in the contexts of aging and cancer. Further research is needed to elucidate the full range of interactions and implications associated with the YWHAEP4 gene.