### CCDC163 Gene Summary

The **CCDC163** (Coiled-Coil Domain Containing 163) gene is predicted to encode a protein that is likely an integral component of the membrane. It is known for computationally mapped potential isoforms, with four potential isoforms identified, suggesting varied functional roles or regulatory mechanisms within different cellular contexts.

#### 1. Associated Genes
While specific gene association data may vary, the following genes have been mentioned in studies related to CCDC163 or within similar contexts, including pathway involvement or shared biological processes:
- **CCDC67** – Involved in ciliary structure and function.
- **CCDC14** – Related to protein structure in cilia.
- **DYNC2H1** – A gene linked to transport and ciliary functions, often discussed in relation to other coiled-coil domain-containing genes.
- **KIF3A** – A gene involved in ciliary transport processes.

Please note that assignments of association can vary based on experimental contexts, tissue types, or specific pathways of interest.

#### 2. Aging and Age-Related Diseases
While direct studies specifically linking CCDC163 to aging or age-related diseases are limited, its involvement as a coiled-coil domain-containing protein suggests a potential role in cellular structure and function, which can be crucial in maintaining cellular integrity over time. Dysfunction in membrane-associated proteins can contribute to various age-related disorders, including:
- **Ciliopathies** – These diseases can relate to defective ciliary formation and structure, associated with aging.
- **Neurodegenerative Diseases** – Alterations in intracellular transport mechanisms, potentially influenced by proteins like CCDC163.

Further research is warranted to elucidate the direct connections and implications of CCDC163 in aging processes or related diseases.

#### 3. Drug Interactions
As of the available information up to October 2023, there are no well-documented drugs or drug classes that specifically target the CCDC163 gene or its encoded protein. However, proteins involved in cellular structure and membrane integrity often interact indirectly with various therapeutic compounds in the context of cellular stress responses or disease conditions. Ongoing drug discovery and systems biology studies may yield new findings regarding interactions in the future.

#### 4. Pathways and Biological Processes
CCDC163 may be involved in several pathways and biological processes, including:

- **Cilium Structure and Function**: Given its predicted role as an integral membrane component, CCDC163 could interact with proteins involved in constructing and maintaining cilia and flagella.
- **Cellular Membrane Dynamics**: It may play a role in membrane organization, dynamics, and organismal development due to its membrane-integral role.
- **Signal Transduction Pathways**: Coiled-coil domain proteins are often involved in scaffolding and facilitating interactions between signaling molecules, impacting various downstream signaling processes.

Further detailed pathway analyses and experimental investigations are necessary to fully elucidate the functional interactions and biological roles of CCDC163 in various cellular contexts.