### DPP10-AS1 Gene Summary

**Gene Symbol:** DPP10-AS1  
**Location:** Chromosome 19

### General Overview
DPP10-AS1 (Dipeptidyl Peptidase 10 Antisense RNA 1) is a long non-coding RNA (lncRNA) that is part of the natural antisense transcript originating from the DPP10 gene locus. The primary function of DPP10-AS1 is implicated in gene regulation, particularly in the modulation of DPP10 expression, which is involved in the immune response and various other physiological processes.

### Associated Genes
DPP10-AS1 is closely associated with the following gene:
- **DPP10:** The protein-coding gene that encodes a member of the serine protease family and plays a role in T-cell activation and differentiation.
  
Other genes with potential associations (based on co-expressions, pathway involvement, or regulatory functions) may include:
- **DPP4:** This gene encodes dipeptidyl peptidase 4, which is associated with metabolic regulation and has implications in diabetes.
- **PDGFRA:** This gene participates in cellular signaling and proliferation, often linked to tumorigenesis.
- **IL7R:** This gene encodes a receptor critical for lymphocyte development.

### Aging and Age-Related Diseases 
Research evidence suggests that lncRNAs such as DPP10-AS1 play a role in cellular aging and age-associated diseases. Changes in the expression levels of DPP10-AS1 might influence:
- **Immune Function:** As the immune system ages, alterations in gene expression including lncRNAs can impact immune response efficacy.
- **Cancer:** Dysregulation of DPP10 and its associated lncRNAs have been linked to various cancers, which are more prevalent in older populations.

### Drug Interactions
Current knowledge does not provide specific drug interactions directly involving DPP10-AS1, but given its association with DPP10 and potential implications in immune function, drugs affecting:
- **Dipeptidyl Peptidase Inhibitors (DPP-4 Inhibitors):** Used in the treatment of type 2 diabetes, such as Sitagliptin and Saxagliptin.

### Pathways and Biological Processes
DPP10-AS1 is involved in several pathways and biological processes, including but not limited to:
- **Regulation of Gene Expression:** Involved in the modulation of the expression and activity of DPP10 and potentially other neighboring genes.
- **Immune Response Processes:** Since DPP10 is associated with T-cell activity, DPP10-AS1 could play a role in immune regulation.
- **Signal Transduction:** Can be implicated in pathways related to cytokine signaling, which has broader implications in inflammation and immune responses.

**Summary:** Though primarily categorized as a non-coding RNA, DPP10-AS1 serves critical regulatory functions possibly affecting aging, immune function, and disease processes. Further research is needed to fully elucidate its roles and potential for therapeutic targeting.