### Overview of the ARL15 Gene

The ARL15 gene (ADP-ribosylation factor-like protein 15) encodes a member of the Arf family of small GTPases, which play crucial roles in intracellular transport and signaling. ARL15 is predicted to have both GTP binding activity and GTPase activity. This gene is primarily located in extracellular exosomes and is involved in various cellular processes, including membrane dynamics and cytoskeletal organization.

### 1. Associated Genes
While specific associations can vary depending on experimental conditions and contexts, ARL15 has been linked to several other genes involved in signaling pathways and cellular mechanisms. These may include:
- **ARF6**: Another member of the Arf family involved in membrane trafficking.
- **RAB proteins**: A family of proteins that interact in vesicular transport dynamics.

Details regarding additional genes associated with ARL15 can arise from studies focusing on specific pathways, networks, or interactions, so databases like KEGG and Reactome may provide further insights.

### 2. Aging and Age-Related Diseases 
Research has highlighted roles of GTPases, including ARL15, in processes that can impact aging, such as cellular senescence, cytoskeletal changes, and cellular stress responses. Specific details related to ARL15 and its direct implications in aging or age-related diseases are less well-documented, but potential links have been observed in:
- **Neurodegenerative Disorders**: Alterations in GTPase functions are often implicated in diseases like Alzheimer's, Parkinson's, and other conditions of cognitive decline. Ongoing studies may clarify the involvement of ARL15 in these contexts.
- **Metabolic Disorders**: Given the association between GTPases and metabolic regulation, ARL15 may also influence conditions like obesity or diabetes.

### 3. Drug Interactions
As of the latest research, there aren't specific drugs explicitly targeting the ARL15 protein known in the clinical setting. However, drugs affecting GTPase signaling pathways may have indirect effects on ARL15 activity. Classes of drugs to consider may include:
- **Modulators of GTPase signaling**: These could include substances that influence the regulatory mechanisms or interact with pathways where ARL15 is involved.

### 4. Pathways and Biological Processes
ARL15 has been implicated in several biological processes:
- **Endocytosis**: ARL15’s role in intracellular transport suggests it may interact with pathways involved in endocytosis and exosomal trafficking.
- **Signal Transduction**: As a GTPase, ARL15 is involved in molecular signaling pathways, enabling the transmission of various signals during cellular responses.
- **Cellular Transport**: Specifically related to protein sorting and vesicular transport mechanisms.
- **Cytoskeletal Dynamics**: It may play a role in maintaining cytoskeletal integrity and functions, which are crucial for numerous cellular processes.

### Conclusion
The ARL15 gene is an intriguing member of the small GTPase superfamily with potential roles in various cellular functions and processes related to intracellular transport and signaling. Its precise implications in aging and specific drug interactions require further research for more definitive conclusions. Continued study may reveal more about its functional pathways and how it might influence health and disease.