### MIR135A1 Gene Overview

**Symbol**: MIR135A1  
**Gene Type**: MicroRNA gene  
**Location**: Typically located in the human genome within specific chromosomal annotations.  

**Function**: The MIR135A1 gene encodes a microRNA that is part of a regulatory mechanism influencing gene expression at the post-transcriptional level. It regulates the stability and translation of target mRNAs by being incorporated into the RNA-induced silencing complex (RISC), which can lead to either translational repression or mRNA degradation.

---

### Additional Details

1. **Associated Genes**:
   - While the summary does not provide a direct list of associated genes, microRNAs, including MIR135A1, often interact with a wide array of target mRNAs. Research indicates that MIR135A1 may have regulatory roles concerning genes involved in developmental processes, apoptosis, and disease pathways, specifically in cancer and metabolic disorders. Some predicted targets based on computational analysis include genes implicated in tumor suppression, cell cycle regulation, and other physiological processes.

2. **Aging and Age-related Diseases**:
   - Studies have suggested a role for MIR135A1 in cellular processes pertinent to aging, such as apoptosis and cellular senescence. Alterations in the expression levels of miRNAs, including MIR135A1, have been linked to age-related conditions like neurodegenerative diseases, cancer, and cardiovascular diseases. For instance, specific regulatory networks involving MIR135A1 may affect cellular responses to stress and inflammation, which are critical in aging.

3. **Drug Interactions**:
   - While specific drugs directly targeting MIR135A1 may not be explicitly documented, miRNA-based therapeutics are an emerging field. Drugs labeled as miRNA mimics or inhibitors could potentially interact with pathways regulated by MIR135A1. As microRNAs like MIR135A1 are implicated in cancer, there may be indirect associations with chemotherapeutic agents. Classes of drugs that modify miRNA expression or function include small molecule inhibitors targeting miRNA maturation or function.

4. **Pathways and Biological Processes**:
   - **Involved Pathways**:
     - **MicroRNA Biogenesis**: The processing of pri-miRNA to mature miRNA.
     - **Gene Expression Regulation**: Modulation of target mRNA stability and translation.
     - **Cell Signaling Pathways**: Influence on pathways relevant to cellular proliferation, apoptosis, and differentiation.
   - **Biological Processes**:
     - **Regulation of mRNA Stability**: Influencing the lifespan of mRNAs within the cell.
     - **Translational Repression**: Attenuating translation efficiency of specific mRNAs.
     - **Gene Silencing**: Contributing to the phenomena of post-transcriptional gene silencing in various biological contexts.

---

Overall, MIR135A1 plays a crucial role in fine-tuning gene expression through its regulatory mechanisms and may be associated with significant biological processes and disease conditions, especially those related to aging. As research progresses, our understanding of this microRNA's roles continues to evolve, potentially revealing new therapeutic targets and strategies.