The NEXN-AS1 gene, characterized mainly as a non-coding RNA, implies that it may not produce a protein that fulfills a central functional role. Here’s an expanded overview based on your request:

### 1. Associated Genes:
NEXN-AS1 is located near the NEXN gene (Nexilin) on chromosome 5. While the primary focus of NEXN-AS1 is as a non-coding RNA, it can be associated with other genes and regulatory elements within its surrounding genomic context. Specifically, interactions with genes involved in cardiac function and muscle development may be relevant due to its chromosomal proximity to NEXN, which is implicated in cytoskeletal structures and cardiac muscle integrity.

### 2. Aging and Age-Related Diseases:
At present, specific studies exploring direct associations between NEXN-AS1 and aging or age-related diseases are limited. However, given that its nearby gene, NEXN, plays a role in cardiac health, there may be indirect implications linking NEXN-AS1 to diseases associated with aging, such as heart disease, where cytoskeletal disruptions are implicated. Understanding the full regulatory functions of NEXN-AS1 is critical for elucidating its potential role in aging. 

### 3. Drug Interactions:
Currently, there are no directly implicated drugs or drug classes that are known to interact with NEXN-AS1. However, since it is located nearby genes involved in cardiovascular health, it may be important in understanding potential responses to cardiovascular drugs that impact protein-coding genes, especially those targeting pathways related to the cytoskeleton or cardiac function. 

### 4. Pathways and Biological Processes:
As a non-coding RNA, NEXN-AS1 may be involved in regulatory pathways rather than direct biological processes like a protein-coding gene. While specific pathways involving NEXN-AS1 have not been well characterized, it may participate in:

- **Gene Regulation:** Non-coding RNAs often serve as regulators of gene expression via mechanisms such as RNA interference or by interacting with chromatin.
- **Cardiac Development and Function:** Given the association with NEXN and its roles in cytoskeletal organization, it could be linked to pathways governing cardiac muscle function and integrity.

### Summary: 
NEXN-AS1, identified mainly as a non-coding RNA of dubious coding potential, requires further investigation to clarify its functional significance, associations with aging or disease, and any potential therapeutic implications. Further studies would ideally explore its interaction network and biological roles, particularly in relation to the NEXN gene and cardiac pathology.