The **ADGRA3** gene is known for encoding an orphan G protein-coupled receptor (GPCR) with potential implications in angiogenesis and neuropsychiatric conditions. Here’s a detailed account of the requested information regarding the gene:

### 1. Associated Genes:
While the summaries provided mention its interaction with the Drosophila disc large tumor suppressor gene, there may be associations with several other genes, including:
- **DLG1**: The human homolog of the Drosophila disc large gene, which plays a central role in cell signaling and maintaining cellular architecture.
- **GNAI proteins**: As a GPCR, ADGRA3 may interact with G alpha i/o proteins involved in intracellular signaling pathways.
- **PTEN**: Implicated in cell growth regulation, it may relate to ADGRA3 in the context of tumorigenesis, especially concerning its role in cancer-related pathways.

### 2. Association with Aging and Age-related Diseases:
While direct studies specifically linking ADGRA3 to aging or age-related diseases are limited, its role in pathways governing cell signaling and the potential involvement in tumor angiogenesis could have implications for:
- **Cancer**: Tumorigenesis and associated angiogenic processes are critical in many cancers often prevalent in older populations.
- **Neuropsychiatric disorders**: Since ADGRA3 is linked to conditions such as bipolar disorder and schizophrenia, mood and cognitive decline in aging may correlate with its expression and functional status.

### 3. Drug Interactions:
Currently, there are no specific drugs or drug classes directly linked to ADGRA3 interactions noted in public databases. As it is an orphan GPCR, the pharmacological aspects are still being explored. Drugs that influence GPCRs in general (e.g., antipsychotics for bipolar disorder) may have indirect effects, but specific interactions require further research.

### 4. Pathways and Biological Processes:
ADGRA3 is involved in several biological processes and pathways, including:
- **Planar Cell Polarity (PCP) Pathway**: A significant pathway for cell orientation and tissue organization, crucial during development.
- **G protein signaling pathway**: As a GPCR, it is likely implicated in various G protein-mediated signaling cascades that regulate cellular responses to external stimuli.
- **Angiogenesis**: Its proposed role in tumor angiogenesis links it to processes involved in the formation of new blood vessels from pre-existing ones, especially in the context of tumor growth.
- **Neurotransmitter signaling**: Given its potential role in neuropsychiatric conditions, ADGRA3 may influence neurotransmission and neuronal development.

In summary, while the ADGRA3 gene has several intriguing associations related to cancer and neuropsychiatric disorders, further research is essential to clarify its role in aging and drug interactions, as well as to elucidate its biological pathways in greater detail.