### SNORD115-7 Gene Overview

**Gene Symbol:** SNORD115-7  
**Gene Type:** Small nucleolar RNA (snoRNA)  

The SNORD115-7 gene is part of the snoRNA family, specifically categorized within the C/D box snoRNAs. These small nucleolar RNAs play crucial roles in the modification of ribosomal RNA (rRNA), primarily through guiding 2’-O-ribose methylation of specific nucleotides, which is essential for the proper assembly and function of ribosomes.

### 1. Associated Genes

While the NCBI and UniProt summaries may not explicitly list these genes, snoRNAs like SNORD115-7 can have interactions and associations with several other genes involved in the ribosome biogenesis and modification processes. Potentially associated genes include:

- **RPS30**: A component of the ribosomal protein family.
- **NOP58**: A nucleolar protein that interacts with snoRNAs.
- **FBL**: A component of the 2'-O-ribose methylation complex.
- **NOLC1**: Involved in ribosomal RNA processing.
  
Additionally, snoRNAs often have overlapping functions, and other members of the SNORD115 family could also be relevant.

### 2. Aging and Age-related Diseases

Research indicates that dysregulation of snoRNA expression, including SNORD115-7, may be linked to aging and age-related diseases, although specific studies directly relating SNORD115-7 to these processes might be limited. Some potential associations include:

- **Neurodegenerative Diseases**: Altered snoRNA expression has been observed in conditions like Alzheimer's disease, where the expression of several snoRNAs changes in affected tissues.
- **Cancer**: Some research indicates that aberrant expression of snoRNAs, including SNORD115-7, may influence tumorigenesis via pathways affecting cell growth and proliferation.

### 3. Drug Interactions

As of the current knowledge up to October 2023, there are no specific drugs or drug classes that are directly known to interact with the SNORD115-7 gene. However, since it is implicated in processes related to ribosomal function, indirectly, drugs affecting ribosomal biogenesis or function (such as certain antibiotics) could have an impact on the pathways involving SNORD115-7.

### 4. Pathways and Biological Processes

The SNORD115-7 gene is involved in several important biological processes, including:

- **Ribosome Biogenesis**: It is essential for the modification and processing of rRNA within nucleolar structures, a critical step in ribosome assembly.
- **Ribosomal RNA Methylation**: Specifically guides the 2’-O-methylation of rRNA, a post-transcriptional modification that is vital for ribosome function and stability.

In terms of broader metabolic or signaling pathways, snoRNAs like SNORD115-7 are indirectly involved in processes that require efficient protein synthesis, impacting cellular growth and proliferation rates.

### Summary

The SNORD115-7 gene plays a pivotal role in ribosomal RNA modification and ribosome assembly as part of the snoRNA family. While specific associations with other genes may aid in understanding its function, ongoing research is needed to fully elucidate its role in aging, disease, and potential therapeutic interactions.