### SNORD95 Gene Overview

**Gene Symbol**: SNORD95  
**Type**: Small nucleolar RNA (snoRNA)

SNORD95 belongs to a class of small nucleolar RNAs (snoRNAs) that are primarily involved in the modification of ribosomal RNA (rRNA), specifically through 2′-O-methylation. These snoRNAs are crucial for the proper processing and maturation of ribosomal RNA inside the nucleolus.

#### 1. Associated Genes
While specific genes directly associated with SNORD95 are not extensively cataloged, snoRNAs like SNORD95 often exhibit associations with various genes involved in ribosome biogenesis and rRNA processing. One may look at other snoRNAs or ribosomal protein genes such as:

- **RRP1B**: Ribosomal RNA processing 1 homolog B.
- **NOP58**: A nucleolar protein that interacts with snoRNAs.
- **NOL5A**: Nucleolar protein involved in ribosome biogenesis.

#### 2. Aging and Age-Related Diseases
Current research regarding the direct association of SNORD95 with aging or age-related diseases is limited. However, disruptions in the function of snoRNAs and related ribosomal biogenesis machinery have been implicated in a variety of age-associated conditions, including:

- **Cancer**: Alterations in snoRNA profiles can be linked to malignancies.
- **Neurodegenerative Diseases**: Impaired ribosome biogenesis has been associated with conditions like Alzheimer's and Parkinson's disease.

While SNORD95 has not been specifically pinpointed in aging research, the pathways and functions it participates in may contribute to, or be reflective of, the cellular changes seen in aging.

#### 3. Drug Interactions
As of the latest available data, there are no specific drugs or drug classes directly known to interact with the SNORD95 gene. However, drugs that target the general process of protein synthesis or ribosome function may indirectly affect its activity. For example, antibiotics that inhibit ribosome function could pertain to snoRNA activity indirectly.

#### 4. Pathways and Biological Processes
SNORD95 is primarily involved in the following biological processes:

- **Ribosome Biogenesis**: A critical process for the production of ribosomes, which are essential for protein synthesis.
- **rRNA Methylation**: SNORD95 contributes to 2′-O-methylation of specific nucleotides in rRNA, a modification that affects ribosome assembly and function.
- **Nucleolar Structure and Function**: Being localized in the nucleolus, SNORD95 plays a role in the overall structure and function of this cellular compartment which is vital for rRNA processing.

#### Conclusion
SNORD95 is a small nucleolar RNA that plays vital roles in ribosome biogenesis and rRNA processing. While direct associations with particular diseases, drugs, or additional genes may not be extensively documented, its broader involvement in the ribosomal machinery and potential implications in aging and disease highlight its importance in cellular biology. Further research could provide more insights into its role in health and disease.