### Gene Summary: FUT8-AS1

**Gene Symbol**: FUT8-AS1

FUT8-AS1, or Fucosyltransferase 8 (FUT8) Antisense RNA 1, is a long non-coding RNA (lncRNA) associated with the fucosyltransferase 8 gene, which is involved in the process of adding fucose, a type of sugar, to glycoproteins. 

### 1. Associated Genes
FUT8-AS1 has been found to be associated with several other genes, particularly those involved in glycosylation and various signaling pathways. While specific interactions may vary based on the context (cell type, disease state, etc.), here are some genes often researched together with FUT8:
- **FUT8** (Fucosyltransferase 8): As the primary gene that this lncRNA is associated with, it plays a crucial role in fucosylation.
- **MGAT5** (Manosyltransferase 5): Involved in glycan biosynthesis.
- **MUC1**: A mucin gene that may be affected by fucosylation processes.

### 2. Aging and Age-Related Diseases
Research involving FUT8-AS1 has indicated its involvement in several age-related mechanisms and diseases:
- **Cancer**: Altered expression of FUT8 and its associated lncRNA has been linked to various cancer types, suggesting a role in oncogenesis or tumor progression.
- **Alzheimer's Disease**: Groups of studies have indicated potential roles of FUT8 in neurodegenerative disorders, highlighting its impact on glycosylation patterns that can influence protein aggregation and toxicity.
- **Metabolic Disorders**: Given that glycosylation can affect insulin signaling and other metabolic pathways, FUT8-AS1 might have implications in age-related metabolic changes.

### 3. Drug Interactions
As of the latest data, no specific drugs have been directly identified that explicitly target FUT8-AS1. However, understanding that it plays a role in glycosylation indicates that compounds acting on the glycosylation process, or drugs that may impact the metabolic pathways influenced by FUT8, could indirectly relate to it. Future research might illuminate specific interactions as the relevance of lncRNAs in pharmacology is still expanding.

### 4. Pathways and Biological Processes
FUT8-AS1 is involved in several key biological processes and pathways:
- **Glycosylation Pathways**: This gene plays a regulatory role in the fucosylation of glycoproteins, which is pivotal in cell signaling, adhesion, and immune responses.
- **Cellular Metabolism**: Given the link between glycosylation and metabolic regulation, it may have implications in broader metabolic pathways.
- **Cancer Pathways**: Through its regulation of FUT8 and glycosylation, FUT8-AS1 may influence pathways involved in cancer progression and metastasis.
- **Neurological Functions**: There may be implications in pathways relevant to neuronal signaling and degeneration, particularly in age-associated neurodegenerative diseases.

### Conclusion
FUT8-AS1 is an important regulatory RNA with implications in fucosylation, aging, cancer, and possibly neurodegenerative diseases. While direct drug interactions may not be well characterized, its role in critical biological pathways emphasizes the need for ongoing research into its potential therapeutic significance.