### PPFIBP1 Gene Overview

**Gene Symbol:** PPFIBP1  
**Chromosomal Location:** This gene is located on human chromosome 11.  

The PPFIBP1 gene encodes a protein that belongs to the liprin family of proteins, which are characterized by their role as scaffolding molecules that facilitate the assembly and function of various cellular complexes. Here is a more detailed breakdown based on your request:

### 1. Associated Genes
While the summaries provided do not specify additional associations, PPFIBP1 has been implicated in pathways and interactions that could involve several other genes. Potentially associated genes may include:

- **LAR (Leukocyte Antigen Related):** Member of the protein-tyrosine phosphatase family that interacts with liprins like PPFIBP1.
- **S100A4 (S100 Calcium Binding Protein A4):** Noted for its role in tumor invasion and is mentioned in interactions with PPFIBP1.
- **PKC (Protein Kinase C family):** Involved in signaling pathways that PPFIBP1 may influence.
- **Integrins:** Involved in focal adhesion and cell-matrix adhesion processes.

### 2. Aging and Age-Related Diseases
Currently, PPFIBP1 has not been directly associated with specific aging-related diseases in literature. However, since it plays a role in cellular adhesion and signaling, it may indirectly influence:

- **Cancer Progression:** Its interaction with S100A4 is relevant in cancer metastasis and could link to age-related cancer susceptibility.
- **Neurodegenerative Diseases:** Given the role of axon guidance in neuronal function, any dysregulation could hypothetically contribute to age-associated cognitive decline.

Further studies would be needed to clarify these associations with aging processes.

### 3. Drug Interactions
To date, there are no specific drugs or drug classes that are widely recognized for directly interacting with the PPFIBP1 gene. However, drugs that target pathways involving LAR family phosphatases, PKC, or signal transduction pathways related to tumor invasion might indirectly affect PPFIBP1 activity or expression.

### 4. Pathways and Biological Processes 
PPFIBP1 is involved in several critical biological processes, including but not limited to:

- **Focal Adhesion Assembly:** The protein is implicated in the disassembly of focal adhesions, which are vital for cell movement and communication with the extracellular matrix.
- **Neuron Development and Axon Guidance:** PPFIBP1’s interaction with LAR phosphatases is crucial for proper neuronal development, playing a role in synaptic structure and function.
- **Cell Migration and Invasion:** Given the interaction with proteins like S100A4, PPFIBP1 potentially plays a role in regulating cell migration mechanisms relevant to cancer metastasis.

Overall, while PPFIBP1 is recognized for its role in cellular scaffolding and interactions with key proteins, further studies could provide deeper insights into its functional implications and associations with various biological processes and diseases.