### ITPKB-AS1 Gene Overview

**Gene Symbol:** ITPKB-AS1

**General Information:**
ITPKB-AS1 is a long non-coding RNA (lncRNA) gene located on the human chromosome. It is an antisense transcript of the inositol-trisphosphate 3-kinase B (ITPKB) gene, which encodes a protein that plays a critical role in several signaling pathways.

### 1. Associated Genes:
While the specifics on genes directly associated with ITPKB-AS1 are limited, it is pertinent to consider its relationship with the ITPKB gene itself, as they share an overlapping region.

**Potential Associated Genes:**
- **ITPKB:** The primary gene associated due to the antisense relationship.
- **Additional lncRNA Genes:** Other lncRNAs that may be involved in the same regulatory networks but are not specifically highlighted in the provided summaries may include various lncRNAs implicated in signaling/metabolism.

### 2. Aging and Age-Related Diseases:
Information directly linking ITPKB-AS1 to aging or age-related diseases is sparse. However, given ITPKB's role in calcium and inositol signaling pathways, it can be hypothesized that dysregulation in these pathways may have implications in conditions such as:
- **Neurodegenerative Diseases:** As calcium signaling is critical in neuronal health.
- **Cancer:** Alterations in signaling mechanisms are often seen with age and malignancies.

The expression levels of various lncRNAs, including ITPKB-AS1, are known to change with age, thus potentially correlating it with the aging process.

### 3. Drug and Drug Classes Interaction:
Detailed information about specific drugs or drug classes that interact directly with ITPKB-AS1 is not readily available in the current literature. However, since ITPKB plays a role in cellular signaling pathways, some compounds that target pathways modulated by ITPKB may indirectly influence the expression or regulatory activity of ITPKB-AS1. Examples may include:
- Modulators of calcium signaling or related pathways.
- Anticancer agents or those targeting neurodegeneration mechanisms.

### 4. Pathways and Biological Processes:
ITPKB-AS1 is associated with several biological processes and signaling pathways, largely relating to its connection to the ITPKB gene.

**Key Pathways and Biological Processes:**
- **Calcium Signaling Pathway:** The ITPKB gene is involved in the calcium signaling pathway, which is crucial for numerous physiological responses.
- **Inositol Metabolism:** Since ITPKB encodes a kinase involved in the metabolism of inositol triphosphate, ITPKB-AS1 is likely implicated in this metabolic pathway.
- **Cell Proliferation and Survival:** Through modulation of signaling pathways that influence cell growth and apoptosis.

Overall, while ITPKB-AS1 is an interesting gene of study, its functional implications, particularly those directly related to aging or pharmacological interactions, require further investigation for a more comprehensive understanding. Given the continued exploration of non-coding RNAs in various biological processes, ongoing research may provide deeper insights into its roles and contributions in health and disease.