### CPEB3 Gene Overview

**Gene Symbol**: CPEB3  
**Gene Function**: CPEB3 (Cytoplasmic Polyadenylation Element Binding Protein 3) is an RNA-binding protein that plays crucial roles in the regulation of mRNA translation and stability. It acts as a translational repressor in the basal state but can function as a translational activator upon neuronal stimulation.

### 1. Associated Genes
In addition to those mentioned in the summary, various other genes and proteins are linked to CPEB3 due to their roles in similar pathways or regulatory networks, including but not limited to:
- **CNOT7**: Part of the CCR4-NOT complex involved in mRNA deadenylation.
- **DLG4 (PSD-95)**: As noted, CPEB3 represses DLG4 translation.
- **GRIA (AMPA Receptors)**: Particularly GRIA1 and GRIA2 related to glutamate signaling.
  
### 2. Aging and Age-Related Diseases
Although specific age-related studies targeting CPEB3 directly may be limited, there are associations inferred from its functions:
- **Cognitive Decline**: Since CPEB3 is involved in memory consolidation, its dysregulation may contribute to neurodegenerative diseases such as Alzheimer's disease.
- **Synaptic Plasticity**: Impairments in synaptic functions regulated by CPEB3 might be seen in aging, impacting learning and memory.
- **Chronic Conditions**: Regulation of genes involved in metabolism and stress responses may connect CPEB3 to conditions prevalent during aging.

### 3. Drug Interactions
Currently, there are no specific drugs or drug classes that are universally recognized to interact directly with CPEB3. However, studies examining the modulation of RNA-binding proteins suggest that:
- **Small Molecule Modulators**: Potential future therapeutics may target RNA-binding proteins like CPEB3.
- **Neuroactive Compounds**: Drugs affecting synaptic transmission, such as certain NMDA receptor antagonists, may indirectly influence pathways regulated by CPEB3 due to its role in synaptic plasticity.

### 4. Pathways and Biological Processes
CPEB3 is involved in several biological processes and pathways, including:
- **mRNA Catabolism**: Participating in the deadenylation and decay of target mRNAs.
- **Cellular Response to Amino Acid Stimulus**: Involved in the signaling processes that sense and respond to amino acid levels.
- **Negative Regulation of Transcription**: Modulating the transcriptional activity of genes through interactions with transcription factors like STAT5B.
- **Hippocampal Long-Term Potentiation**: Essential for processes related to memory and learning.

### Summary
CPEB3 is a multi-functional RNA-binding protein implicated in translation regulation, memory consolidation, and possibly a mediator of age-related synaptic plasticity changes. Its involvement in mRNA deadenylation and modulation of important synaptic genes highlights its potential significance in cognitive health and age-related diseases. Further research is necessary to uncover the precise connections and therapeutic implications related to this gene.