### IKBKGP1 Gene Overview

**Gene Symbol:** IKBKGP1  
**Aliases:** IKBKE, IKBKGP, IκB kinase gamma pseudogene 1  
**Location:** Chromosome 3; the gene is found in the vicinity of S100 and IKBKE, among others.  
**Function:** The IKBKGP1 gene is believed to be a pseudogene, which means it does not produce a functional protein. It is suggested to arise from the IKBKE gene and may share some homology with it.

### Associated Genes

While the summaries do not specify other genes directly associated with IKBKGP1, through its context and presence within the chromosomal region, it is linked to:

- **IKBKE (Inhibitor of Nuclear Factor Kappa B Kinase E):** It is a functional gene known to play a role in immune response.
- **S100A genes:** Members of the S100 family are involved in various cellular processes, including differentiation, proliferation, and inflammatory responses.

### Aging and Age-Related Diseases

Direct associations of IKBKGP1 with aging or age-related diseases may not be well established due to its nature as a pseudogene. However, insights can be inferred from the functions of its associated genes like IKBKE, which are involved in pathways that can impact cellular stress responses and inflammation. These pathways are often dysregulated in aging and age-related diseases such as:

- **Inflammation-related disorders:** Chronic inflammation is associated with aging, and dysregulation may lead to age-related conditions like cardiovascular diseases and neurodegenerative disorders.
- **Cancer:** The NF-kB signaling pathway, which involves IKBKE, is pivotal in many cancers, and malfunction in this pathway can lead to tumor progression.

### Drug Interactions

Specific drug interactions with IKBKGP1 itself may not be documented, largely due to its pseudogene status. However, drugs targeting the IKBKE gene or the NF-kB signaling pathway include:

- **IκB Kinase Inhibitors:** These may affect downstream processes that are relevant in inflammatory conditions and possibly cancer.
- **Corticosteroids:** These are broadly used to counteract inflammation and function through pathways that involve NF-kB.

### Pathways and Biological Processes

**Biological Pathways and Processes:**
- **NF-kB signaling pathway:** IKBKGP1's closest functional counterpart, IKBKE, participates in this crucial cellular signaling pathway regulating immune response, inflammation, and cell survival.
- **Cellular Response to Stress:** Related genes and pathways may be involved in how cells respond to various stressors, which could be linked indirectly to aging processes.

### Summary

While IKBKGP1 may not demonstrate direct functional output due to its pseudogene classification, its association with IKBKE and location near genes related to inflammation and stress responses positions it as a potential contributor to mechanisms relevant to aging and disease. Further research may reveal more nuanced associations.