### SNORD115-20 Gene Overview

**Gene Symbol:** SNORD115-20  
**Type:** Small nucleolar RNA gene  

**Function:** SNORD115-20 is part of the SNORD115 (small nucleolar RNA, C/D box 115) family, primarily functioning in the process of pre-rRNA processing and the modification of rRNA. These small nucleolar RNAs are critical for the biogenesis of ribosomes, as they guide the modification of rRNA through methylation.

### Associated Genes
SNORD115-20 is associated with various genes involved in ribosome biogenesis and rRNA processing. Several of these include:

- **FBL**: Fibrillarin is a nucleolar protein that plays a role in rRNA processing and modification.
- **Nop56**: A component of the box C/D small nucleolar ribonucleoproteins (snoRNPs), involved in rRNA methylation.
- **Nop58**: Another component of snoRNPs that works alongside FBL and Nop56.

While no direct association with specific genes linked to age-related diseases has been confirmed, the overall functionality of snoRNAs in ribosome biogenesis connects them indirectly with cellular aging processes.

### Aging and Age-Related Diseases
Currently, there is limited evidence directly linking SNORD115-20 to aging or age-related diseases. However, small nucleolar RNAs, and snoRNAs in general, influence cellular metabolism and may reflect changes in cellular functionality associated with aging. Persistent dysregulation of RNA processing pathways can be related to age-related diseases, including neurodegenerative diseases, where altered RNA metabolism is observed.

### Drug Interactions
As of the latest data, no specific drugs or drug classes are known to interact directly with SNORD115-20. However, compounds that modulate ribosomal function or RNA processing may indirectly influence the activity of snoRNAs. Some classes of drugs that affect RNA metabolism (e.g., nucleoside analogs or certain antiviral agents) could theoretically impact small nucleolar RNAs' activity.

### Pathways and Biological Processes
SNORD115-20 is primarily involved in the following pathways and biological processes:

- **Ribosome Biogenesis**: As part of the snoRNA family, it plays a vital role in assembling ribosome components.
- **Pre-rRNA Processing**: SNORD115-20 guides modifications on pre-rRNA substrates, facilitating their maturation into functional rRNA.
- **RNA Methylation**: SNORD115-20 may contribute to the methylation of specific rRNA sites, crucial for the stability and function of ribosomes.

### Summary
In summary, SNORD115-20 is a small nucleolar RNA with a significant role in the modification and processing of rRNA, essential for ribosome biogenesis. Although associated with other nucleolar proteins, its direct implications in aging or specific drug interactions remain to be fully elucidated. The broader category of snoRNAs, including SNORD115-20, may share connections to age-related changes in cellular function, although more research is necessary to clarify these relationships.