### ECI2-DT Gene Overview

**Gene Symbol:** ECI2-DT  
**Alternative Names:** Previously known as ECI2 natural antisense transcript. 

**General Description:**
The ECI2-DT gene is known to produce a long non-coding RNA (lncRNA) that is associated with the ECI2 gene. ECI2 (Enoyl-CoA hydratase) is involved in fatty acid metabolism, particularly in the β-oxidation of unsaturated fatty acids.

### 1. Associated Genes
Currently, no specific associated genes have been described in the summaries from NCBI and UniProt. However, given the role of ECI2, other metabolic genes can be indirectly related, including:
- **ACAD10**: Possibly involved in fatty acid metabolism.
- **ECSIT**: Plays a role in immune and metabolic functions.
- **PPARs (Peroxisome proliferator-activated receptors)**: These are involved in lipid metabolism and may interact with lncRNAs like ECI2-DT in regulatory networks. 

### 2. Aging and Age-Related Diseases
While specific studies linking ECI2-DT directly to aging or age-related diseases are limited, its association with ECI2 implicates potential relevance to metabolic syndromes where fatty acid metabolism is disrupted. Age-related diseases such as diabetes, obesity, and cardiovascular diseases are often linked to dysregulation in metabolic pathways.

- **Metabolic Deregulation:** Given that ECI2 is involved in fatty acid metabolism, transcriptional changes in ECI2-DT could be implicated in such age-related metabolic disturbances.
- **Inflammation:** LncRNAs in general play roles in inflammatory processes. Since chronic inflammation is a hallmark of aging, any regulatory role of ECI2-DT could influence age-related inflammation.

### 3. Drug Interactions
Currently, no specific drugs or drug classes are documented to interact directly with the ECI2-DT gene. However, due to its involvement in lipid metabolism, medications impacting fatty acid pathways (such as fibrates or statins) could theoretically influence its expression indirectly.

### 4. Pathways and Biological Processes
The ECI2-DT gene is implicated in the following biological processes and pathways:
- **Fatty Acid Metabolism:** Involved in pathways related to the metabolism of unsaturated fatty acids.
- **Metabolism of Lipids:** Plays a critical role in the regulation of lipid homeostasis, potentially through the modulation of ECI2 gene expression.
- **Regulation of Gene Expression:** As a long non-coding RNA, ECI2-DT may influence transcriptional regulation of adjacent genes or participate in chromatin remodeling.
- **Cellular Stress Response:** There is potential involvement in stress response pathways due to links with metabolic processes that are altered under cellular stress conditions.

### Summary
The ECI2-DT gene is a long non-coding RNA related to fatty acid metabolism, with potential implications in the regulation of metabolic pathways associated with aging and metabolic diseases. While specific drugs and detailed regulatory pathways need further investigation, the gene’s function suggests possible interactions and influences that merit further research, particularly in the context of aging and metabolic health.