### Overview of FAM135A-AS1 Gene

**Gene Symbol:** FAM135A-AS1

FAM135A-AS1 is classified as a long non-coding RNA (lncRNA), which means it does not code for a protein but plays a role in regulating various biological processes, including gene expression, cell proliferation, and differentiation. 

### 1. Associated Genes

FAM135A-AS1 is associated with several genes, particularly those involved in cellular processes and gene regulation, although specific genes may not be frequently cited in literature. Some noted associations could include, but are not limited to:
- **FAM135A:** The sense strand of the FAM135A-AS1 overlaps with the FAM135A gene.
- **Other lncRNAs:** Numerous surrounding or competing lncRNAs in the same genomic region may modulate its expression or function.

Further investigations using bioinformatic tools or databases such as KEGG, Reactome or STRING may reveal additional interacting or associated gene networks.

### 2. Aging and Age-Related Diseases

Recent studies have implicated various non-coding RNAs, including lncRNAs like FAM135A-AS1, in aging and age-related diseases. Here are some potential connections:
- **Cellular Senescence:** Long non-coding RNAs can influence pathways related to cellular senescence, a critical process associated with aging.
- **Cancer:** Some studies have shown that lncRNAs, including FAM135A-AS1, can play a role in the development and progression of age-related malignancies by affecting tumor suppressor genes or oncogenes.
- **Neurodegeneration:** Evidence suggests that altered expression profiles of lncRNAs might be involved in neurodegenerative diseases, which are commonly associated with aging.

As of the latest data leading up to October 2023, the specific role of FAM135A-AS1 in aging-related processes may need further elucidation.

### 3. Drug Interactions

Currently, there are no specific drugs or drug classes universally recognized for direct interaction with FAM135A-AS1. However, the regulatory mechanisms of lncRNAs may influence the effectiveness of therapies targeting related pathways. That's being said:
- **Chemotherapeutic Agents:** Certain cancer treatments might indirectly affect the expression of FAM135A-AS1 if it is found to modulate processes relevant to cancer biology.

Further research would be required to identify any novel drug interactions or modifications due to FAM135A-AS1 expression.

### 4. Pathways and Biological Processes

FAM135A-AS1 is implicated in various biological processes and signaling pathways, such as:
- **Gene Expression Regulation:** lncRNAs generally regulate chromatin remodeling, transcriptional control, and post-transcriptional modifications.
- **Cell Cycle Regulation:** Potentially involved in modulating cell cycle progression, impacting growth and differentiation.
- **Response to Stress Signals:** May play a role in cellular responses to hypoxia or oxidative stress.

Specific associations with established pathways could be identified by searching consensus databases like KEGG for signaling pathways influenced by FAM135A-AS1 or its target genes.

### Conclusion

While the FAM135A-AS1 gene is a long non-coding RNA with potential roles in cellular regulation and disease, more detailed studies are needed to fully understand its functions and implications in aging and drug interactions. Further exploration in biological databases and experimental studies may yield more insight into its significance in health and disease.