### SNORD87 Gene Overview

**Gene Symbol:** SNORD87

**Description:** SNORD87, also known as small nucleolar RNA domain 87, is part of the C/D box small nucleolar RNA (snoRNA) family. These snoRNAs are primarily involved in the biogenesis of ribosomal RNA (rRNA) and play crucial roles in the modification and processing of rRNA within the nucleolus, a sub-compartment in the cell nucleus where ribosome synthesis occurs. 

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### 1. Associated Genes

While specific associations are not widely documented, snoRNAs like SNORD87 often participate in the regulation of neighboring genes due to their roles in RNA processing. The following genes can be indirectly associated due to their involvement in ribosome biogenesis:

- **NR5A2:** A transcription factor that may interact with transcripts modified by snoRNAs.
- **P53 (TP53):** Involved in cellular stress and response mechanisms, which can be affected by ribosome biogenesis dysfunction.

### 2. Aging and Age-Related Diseases

Current literature does not specifically highlight direct associations between SNORD87 and aging or age-related diseases. However, several key points can be noted:

- **Ribosome Biogenesis:** Defects in ribosome biogenesis, where snoRNAs play a crucial role, have been implicated in various age-related diseases, including cancer and neurodegenerative disorders such as Alzheimer's and Huntington's diseases.
- **Cellular Senescence:** Alterations in snoRNA expression profiles may influence cellular senescence, which is a prominent feature of aging and age-related pathologies.

### 3. Drug Interactions

No specific drugs or drug classes are currently documented to interact directly with SNORD87. However, given its role in ribosome biogenesis, alterations in the expression or function of snoRNAs can impact responses to certain chemotherapeutic agents that target ribosome function or affect nucleolar activity.

### 4. Pathways and Biological Processes

SNORD87 is involved in several important biological processes:

- **rRNA Processing:** SNORD87 is responsible for guiding the modification of ribosomal RNA, a crucial step in the formation of functional ribosomes.
- **Ribosome Biogenesis:** The gene plays a critical role in the production and assembly of ribosomal subunits necessary for protein synthesis.
- **Gene Regulation:** Modifications of rRNA facilitated by snoRNAs like SNORD87 may indirectly influence the expression of genes involved in cell growth and proliferation.

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### Summary

The SNORD87 gene is an essential component of the ribosomal RNA modification process and is implicated in the larger context of cellular biology related to growth and proliferation. While no direct connections to aging or specific drug interactions are established, the broad implications of ribosomal dysfunction touch on various age-related processes and disease states. Ongoing research may further elucidate the role of snoRNAs like SNORD87 in the molecular underpinnings of health and disease.