### CCDC117 Gene Overview

**Gene Symbol:** CCDC117  
**Function:** The CCDC117 gene encodes a protein that plays a significant role in cellular processes such as DNA repair, cell cycle progression, and cell proliferation, particularly through its interaction with the protein CIAO2B.

### 1. Associated Genes
CCDC117 has been implicated in interactions with various proteins and genes involved in cell cycle regulation and DNA repair pathways. Some genes and proteins associated with or potentially interacting with CCDC117 include:

- **CIAO2B:** Direct interaction partner that is involved in protein trafficking and mitochondrial function.
- **TP53:** Known as the tumor suppressor gene, may have indirect relationships through its role in DNA damage response.
- **BRCA1/BRCA2:** These genes are crucial for DNA repair via homologous recombination, where CCDC117 may play supporting roles.
- **RAD51:** Involved in the homologous recombination repair of DNA double-strand breaks and could be indirectly associated due to shared pathways.

### 2. Aging and Age-Related Diseases
While specific studies directly linking CCDC117 to aging or age-related diseases may be limited, its functions in DNA repair and cell proliferation mean that dysregulation could potentially relate to age-associated conditions such as:

- **Cancer:** Impaired DNA repair mechanisms can lead to genomic instability, a hallmark of many cancers that tend to increase in prevalence with age.
- **Neurodegeneration:** As cellular mechanisms decline with age, proper functioning of DNA repair and cell cycle regulation are critical, where CCDC117 might play a role.
- **Cardiovascular Diseases:** Aberrant cell proliferation and insufficient repair mechanisms within cardiovascular tissues over time may also lead to degeneration and disease.

### 3. Drug Interactions
Currently, there are no specific drugs or drug classes explicitly documented to interact with CCDC117 itself. However, since CCDC117 is involved in DNA repair and potential cancer pathways, therapies targeting DNA repair mechanisms or pathways may indirectly affect or interact with the pathways in which CCDC117 is involved. Drug classes that might be relevant include:

- **DNA Repair Inhibitors:** Such as PARP inhibitors (e.g., Olaparib, Rucaparib), given the connection of DNA repair processes in cancer therapeutics.
- **Antineoplastic Agents:** These often target rapidly dividing cells, which may indirectly implicate the role of CCDC117 in a tumorigenic context.
  
### 4. Pathways and Biological Processes
CCDC117 is involved in several critical biological pathways and processes:

- **DNA Repair Mechanisms:** Crucial for maintaining genomic integrity.
- **Cell Cycle Regulation:** Involvement in stages of the cell cycle that are critical for cell division and tumorigenesis.
- **Cell Proliferation:** Key for growth and repair processes, especially in response to cellular damage or stress.
  
Additionally, it is important to mention any involvement in other signaling pathways or cellular processes may include apoptosis, response to oxidative stress, and cellular metabolism, marking CCDC117 as a potential player in maintaining cellular homeostasis.

### Summary
CCDC117 is an integral gene in processes such as DNA repair and cell cycle regulation, with implications in aging and age-related diseases, particularly cancer. While no specific drugs directly target this gene, its pathways may intersect with several therapeutic interventions aimed at DNA repair or cancer treatment. Future research may be pivotal in further elucidating the role of CCDC117 in these contexts.