### IRF2BPL Gene Overview
**Gene Symbol:** IRF2BPL  
**Function:** The IRF2BPL gene encodes a transcription factor that functions as a probable E3 ubiquitin protein ligase, likely involved in the ubiquitin-proteasome pathway to regulate protein degradation. It has roles in the Wnt signaling pathway and in female reproductive function, potentially affecting the development and maintenance of the central nervous system.

### 1. Associated Genes
While the provided summaries do not indicate specific genes associated with IRF2BPL, the following genes may be connected through reported interactions or pathways:

- **CTNNB1**: This gene encodes β-catenin, which is implicated in the Wnt signaling pathway and acts as a target for degradation by IRF2BPL.
- **FOXF2**: This transcription factor is known to be upstream of IRF2BPL in the regulatory pathway affecting Wnt signaling.
- **GNRH1**: The gonadotropin-releasing hormone is directly mentioned as a potential target for transactivation by IRF2BPL.
- **PENK**: This gene encodes proenkephalin, which may be repressed by IRF2BPL.

### 2. Aging and Age-Related Diseases
As of October 2023, there is no direct and specific association reported between IRF2BPL and aging or age-related diseases in available literature. However, since it plays a role in neuronal maintenance and the central nervous system, dysregulation of IRF2BPL could potentially contribute to neurodegenerative conditions or cognitive decline, which are often observed during aging.

### 3. Drugs and Drug Classes
As of the last update, there are no specific drugs or drug classes directly documented to interact with IRF2BPL. Due to its involvement in cellular signaling pathways, it is worth monitoring for potential implications in drug target discovery, particularly in the fields of oncology (due to its regulation of the Wnt pathway) and reproductive health.

### 4. Pathways and Biological Processes
IRF2BPL is associated with several biological processes and pathways:
- **Wnt Signaling Pathway**: IRF2BPL negatively regulates Wnt signaling through the degradation of CTNNB1.
- **Transcriptional Regulation**: It regulates gene transcription by activating the GNRH1 promoter and repressing the PENK promoter, impacting reproductive hormone pathways.
- **Ubiquitin-Mediated Proteolysis**: As a probable E3 ligase, it participates in the proteasome-mediated degradation of proteins, affecting various cellular processes.
- **Neurodevelopment and Maintenance**: Given its role in the central nervous system, it may be involved in processes associated with neural development and maintenance.

### Summary
The IRF2BPL gene is an essential component in transcriptional regulation related to female reproductive function and has significant roles in modulating the Wnt signaling pathway. Current knowledge suggests potential links to neurodevelopment and cellular homeostasis, with ongoing research required to uncover deeper insights into its involvement in aging and drug interactions.