### FGF12-AS2 Gene Overview

#### General Information
- **Gene Symbol:** FGF12-AS2
- **Type:** Long non-coding RNA (lncRNA)
- **Location:** The FGF12-AS2 gene is situated on chromosome 12 in humans and is an antisense transcript to the FGF12 gene. 

### Associated Genes
FGF12-AS2 has been linked to several other genes indirectly through its function and expression patterns, often related to the regulation of the adjacent gene FGF12, which is involved in neurodevelopment and synaptic functions. Specific associated genes include, but are not limited to:
- **FGF12**: As the primary target gene, which is essential in neuronal excitability.
- **Other FGF family members**: Various fibroblast growth factors that may have regulatory interactions.
- Potentially involved with genes in cellular signaling and growth pathways, although specific associations require more focused studies.

### Aging and Age-Related Diseases
FGF12-AS2, like other lncRNAs, has been implicated in various cellular processes that correlate with aging, though direct studies might be sparse. The expression of FGF12 and its associated lncRNAs can affect neural plasticity, synaptic integrity, and neuronal resilience, which are critical in neurodegenerative diseases associated with aging, such as:
- **Alzheimer's Disease**: Altered expression of LncRNAs may influence amyloid precursor protein processing or tau pathology.
- **Parkinson’s Disease**: Changes in neuronal signaling pathways influenced by FGF12 and its regulatory mechanisms may be factors in pathogenesis.

### Drug Interactions
Currently, there are no specific drugs identified that directly target FGF12-AS2; however, the pathways it influences can be significant for:
- **Neuroprotective drugs**: Given the involvement of FGF12 in neuronal pathways, modulation of lncRNAs like FGF12-AS2 could potentially influence the efficacy of these drugs.
- **Antisense oligonucleotides (ASOs)**: In a broader sense, research into lncRNAs presents opportunities for therapeutic intervention via ASOs that may modulate the expression of FGF12-AS2 in specific conditions.

### Pathways and Biological Processes
FGF12-AS2 is associated with several biological processes:
- **Neuronal Development**: Influences the regulation of genes involved in neurogenesis and maturation, particularly in the context of synaptic plasticity.
- **Cell Signaling Pathways**: Affects pathways related to growth factor signaling, particularly with fibroblast growth factors (FGFs) that affect cellular proliferation, differentiation, and survival.
- **Epigenetic Regulation**: LncRNAs, including FGF12-AS2, can play roles in chromatin remodeling and gene expression regulation by interacting with transcription factors and chromatin modifiers.

Overall, while specific literature directly linking FGF12-AS2 to drug interactions and age-related diseases may be limited, its role as a lncRNA in developmental and regulatory pathways suggests a significant biological impact worth further research especially in the context of neurobiology and associated diseases.