The PEA15 gene (Phosphoprotein Enriched in Astrocytes 15) encodes a multifunctional protein involved in several cellular processes, particularly those relating to apoptosis and glucose metabolism. Below, I will organize the requested information in a structured manner.

### 1. Associated Genes
PEA15 has been implicated in interactions with various other genes and proteins. Some notable associations include:
- **SLC2A1 (GLUT1)**: A glucose transporter that PEA15 regulates.
- **SLC2A4 (GLUT4)**: Another glucose transporter involved in insulin signaling that is modulated by PEA15.
- **RPS6KA3 (RSK2)**: As mentioned, PEA15 inhibits the activity of RPS6KA3.
- **TP53**: There are indications that PEA15 may interact with TP53, a critical regulator of apoptosis and cell cycle control.

### 2. Aging and Age-Related Diseases
While specific research directly linking PEA15 to aging is limited, there are several indirect associations:
- **Insulin Resistance & Type 2 Diabetes**: Given that PEA15 is overexpressed in type 2 diabetes, its role in insulin resistance suggests it may also play a part in metabolic dysregulation associated with aging.
- **Neurodegeneration**: As PEA15 is enriched in astrocytes, its dysfunction may contribute to neurodegenerative diseases, which often correlate with aging processes.

### 3. Drugs or Drug Classes Interacting with PEA15
Specific drugs directly targeting PEA15 may not be well-defined. However, certain classes of drugs that may influence pathways involving PEA15 include:
- **Protein kinase C (PKC) inhibitors**: These could potentially alter PEA15 functions given its substrate role.
- **Antidiabetic medications**: As PEA15 is involved in insulin signaling, some antidiabetic agents could indirectly influence its activities, though specific interactions may require further research.

### 4. Pathways and Biological Processes
PEA15 is involved in several key pathways and biological processes, such as:
- **Apoptosis Regulation**:
  - Inhibition of CASP8 and other apoptotic signaling pathways, thereby promoting cell survival.
- **MAPK Signaling**:
  - Modulation of the ERK MAP kinase cascade, affecting cellular responses to external signals.
- **Glucose Metabolism**:
  - Regulation of glucose transporters (SLC2A1 and SLC2A4) which are critical in glucose uptake and insulin signaling.
- **Integrin Activation**:
  - Blocking Ras-induced inhibition of integrin-mediated cell adhesion and signaling.

### Summary
PEA15 is an influential gene in the regulation of cell survival and metabolic processes, particularly in relation to insulin sensitivity. Its associations with other genes, potential implications in age-related conditions, and involvement in key biological pathways underscore its importance in cellular physiology and pathology. Further research may elucidate more precise interactions and therapeutic targets associated with PEA15 in various diseases.