The **MAN1B1-DT** gene, also known as a long non-coding RNA (lncRNA), is transcribed from the opposite strand of the **MAN1B1** gene, which encodes a mannosidase enzyme involved in protein glycosylation. Here’s a detailed breakdown based on your requirements:

### 1. Associated Genes
MAN1B1-DT has been studied for its potential regulatory roles related to the MAN1B1 gene. In addition to **MAN1B1**, other related genes and proteins may include:

- **MAN1A1**: Another gene encoding an alpha-mannosidase that is involved in the glycosylation process.
- **MAN1A2**: A gene within the same gene family that also contributes to glycan processing.

It’s important to note that as a lncRNA, **MAN1B1-DT** might influence the expression of nearby genes through various regulatory mechanisms, although specific interacting genes beyond MAN1B1 itself require further research to clarify.

### 2. Aging and Age-Related Diseases
While there is limited direct information available regarding **MAN1B1-DT** and its specific association with aging or age-related diseases, the **MAN1B1** gene's role in glycosylation suggests potential implications for:

- **Age-related cognitive decline**: Glycosylation processes can affect cellular signaling pathways and protein interactions, which are essential in maintaining cognitive functions.
- **Immune system aging**: Aberrant glycosylation patterns have been implicated in aging-related immune dysfunction, particularly in the modulation of immune responses with age.

More explicit connections for **MAN1B1-DT** would necessitate further investigation into how this lncRNA regulates its associated genes in the context of aging.

### 3. Drug Interactions
As of the latest data up to October 2023, there are no well-documented drugs or drug classes that are specifically known to interact with **MAN1B1-DT**. Given its status as a long non-coding RNA, direct pharmacological targeting may not be common, but further research may uncover indirect relationships, particularly through pathways affected by glycosylation.

### 4. Pathways and Biological Processes
**MAN1B1-DT** is involved in several biological processes and pathways primarily through its association with **MAN1B1** and implications for protein glycosylation. These include:

- **Protein glycosylation**: The process by which carbohydrate moieties are attached to proteins, significantly influencing protein folding, stability, and function.
- **Endoplasmic Reticulum (ER) stress response**: Both mannosidases play a role in the regulation of protein quality control in the ER.
- **Cell-cell signaling**: Glycosylation affects various signaling pathways by modifying protein interactions.
- **Innate immune response**: Glycosylation is crucial for proper immune function, where lncRNAs can modulate responses to pathogens.

Due to the evolving nature of research in the field of lncRNAs, ongoing studies may reveal more associations, roles, and implications for **MAN1B1-DT** regarding other genes, aging, drug interactions, and biological pathways.