**Gene Overview: SNORA55**

**Gene Symbol:** SNORA55

SNORA55, also known as Small Nucleolar RNA 55, is a gene that encodes a small nucleolar RNA (snoRNA). This snoRNA plays a vital role in the modification and maturation of ribosomal RNA (rRNA), which is essential for the production of ribosomes, the cellular machinery responsible for protein synthesis. 

### 1. Associated Genes
While the summaries from NCBI and UniProt typically focus on the core functionalities of genes, many snoRNAs, including SNORA55, are involved in larger complexes or processes that may interact with various genes. Although specific direct associations for SNORA55 may not be extensively documented, it often interacts with other snoRNAs and ribosomal protein genes (e.g., RPS family genes) due to its role in rRNA methylation and processing. Furthermore, any dysregulation might influence genes involved in RNA processing, splicing factors, or stress response pathways.

### 2. Aging and Age-Related Diseases
The specific role of SNORA55 in aging or age-related diseases has not been thoroughly investigated, but snoRNAs in general have been implicated in cellular senescence, cancer, and other age-associated processes. Their involvement in the maintenance and modification of rRNA suggests that alterations in their expression could influence cellular function and contribute to the decline seen with aging. Further studies may reveal potential links to age-related diseases like neurodegeneration or other conditions characterized by impaired cellular growth and proliferation.

### 3. Drug Interactions
Currently, there is no specific drug or drug class directly known to interact with the SNORA55 gene. However, general modulators of RNA activity, such as small molecules that target snoRNP (snoRNA-protein complexes), may indirectly affect its function, although specific interactions with FDA-approved drugs remain to be elucidated. Similarly, therapeutic strategies targeting RNA metabolism may influence the activity of genes like SNORA55, particularly in the context of cancer or therapies addressing RNA dysregulation.

### 4. Pathways and Biological Processes
SNORA55 is primarily involved in:

- **rRNA modification:** As a snoRNA, SNORA55 is part of the machinery that modifies rRNA, specifically through methylation, which is crucial for the integrity and function of ribosomes.
- **Ribosome biogenesis:** The gene plays a significant role in the processing and maturation of ribosomal RNA components, an essential process in the formation of functional ribosomes.
- **Gene expression regulation:** By influencing rRNA processing, SNORA55 indirectly affects the overall protein production in a cell, thereby impacting gene expression profiles.
- **Nuclear processing:** Small nucleolar RNAs are generally found in the nucleolus and are involved in various aspects of RNA nucleolytic processing and regulation.

In summary, while the SNORA55 gene may not have extensive direct associations with aging, drug interactions, or specific pathway enrichments beyond its role in rRNA modification, understanding its contribution to ribosome biogenesis and the delicate balance of cellular functions underscores its potential implications in broader biological contexts. Further research is necessary to clarify its roles and potential applications in therapeutic contexts.