### RSRC2 Gene Overview

**Gene Symbol:** RSRC2  
**Enables:** RNA binding activity  
**Protein Family:** RSRC2 family

**General Description:**  
The RSRC2 gene (Arginine-Serine-Rich Coiled-Coil 2) encodes a protein that is involved in RNA binding and splicing regulation, playing a vital role in pre-mRNA splicing and other processes related to RNA metabolism. It is known to contain characteristic RNA recognition motifs (RRMs) that facilitate its interactions with RNA.

### 1. Associated Genes
RSRC2 is associated with several other genes, particularly those involved in RNA splicing and processing. Some of these genes include:

- **SNRPB:** Component of the spliceosome involved in pre-mRNA splicing.
- **PRPF31:** Essential for the formation of the spliceosome.
- **U2AF1:** Involved in pre-mRNA splicing as a part of the spliceosomal U2 auxiliary factor.

Additionally, it has been implicated in relationships with genes involved in neurodegenerative diseases and stress response pathways, though more specific interactions may depend on ongoing research.

### 2. Aging and Age-Related Diseases
The RSRC2 gene has been studied in the context of aging and age-related diseases such as neurodegeneration and certain cancers. 

- **Aging:** The expression of RSRC2 may decline with age, impacting RNA splicing efficiency and contributing to cellular senescence.
- **Neurodegenerative Diseases:** Alterations in RSRC2 expression have been observed in neurodegenerative diseases such as Alzheimer's disease, where dysregulation of RNA metabolism is a significant factor.

Moreover, the association of RSRC2 with genes regulating cell cycle and apoptosis may link it to cancer progression, which often correlates with aging.

### 3. Drug Interactions
While specific drugs directly targeting RSRC2 are not broadly established in clinical applications, the gene may interact indirectly with various cancer therapeutics and drugs that modulate RNA processing and splicing.

- **Antisense Oligonucleotides:** Some therapies targeting splicing defects may have downstream effects on RSRC2 activity.
- **Chemotherapeutic Agents:** Drugs that alter the RNA processing landscape may impact RSRC2 functionality due to its RNA-binding properties.

### 4. Pathways and Biological Processes
RSRC2 is involved in several key pathways and biological processes, including but not limited to:

- **mRNA Splicing:** RSRC2 plays a critical role in the spliceosome assembly and activity.
- **Regulation of Gene Expression:** By binding to pre-mRNA and affecting its splicing, RSRC2 has a role in post-transcriptional regulation of gene expression.
- **RNA Metabolism Pathways:** Involved in the broader context of RNA processing and metabolic pathways, RSRC2 contributes to mRNA surveillance mechanisms.
- **Cell Cycle Regulation:** Its interaction with splicing factors may implicate RSRC2 in cell cycle regulation processes.

In summary, RSRC2 is significant in RNA binding and the regulation of various RNA processes, with implications in aging, neurodegenerative diseases, and potential indirect associations with therapeutics targeting RNA metabolism. Its functional network continues to be an area of interest for ongoing research.