### Gene Overview: SNORD116-30

**Gene Symbol:** SNORD116-30  
**Function:** SNORD116-30 is a member of the small nucleolar RNA (snoRNA) family, which are primarily involved in the modification and processing of ribosomal RNA (rRNA). This particular snoRNA is known to be involved in guiding the 2’-O-ribose methylation of target nucleotides within pre-rRNA, which is essential for the proper assembly and function of ribosomes.

### 1. Associated Genes
While specific associations may vary based on different studies and contexts, SNORD116-30 is known to be part of the SNORD116 gene cluster located on chromosome 15 (specifically in the region associated with Prader-Willi syndrome). Other genes that may be functionally or genomically associated with SNORD116-30 include:
- SNORD116 (the entire cluster)
- Other snoRNAs within the same cluster which might have related functions in rRNA modification.
- Genes related to Prader-Willi syndrome, such as SNRPN (Small Nuclear Ribonucleoprotein Polypeptide N), which is associated with the imprinting processes in this region.

### 2. Aging or Age-Related Disease Associations
While research specifically linking SNORD116-30 to aging or age-related diseases is limited, snoRNAs, including SNORD116-30, play a crucial role in ribosome biogenesis and protein synthesis. Age-related decline in ribosome production can affect cellular homeostasis and overall biological processes, potentially contributing to age-related diseases.

Additionally, mutations or epigenetic changes in the SNORD116 gene cluster have been implicated in neurodevelopmental disorders and may relate to mRNA regulation impacting neurodegenerative conditions, though direct links to typical aging markers or diseases need further exploration.

### 3. Drug or Drug Class Interactions
As of the most recent data, no specific drugs or drug classes have been directly tied to interactions with SNORD116-30. However, due to its function in ribosomal RNA modification and potential implications in gene expression, therapies affecting general transcriptional regulation, or ribosomal function in pathologies, could theoretically impact the expression or function of the SNORD116-30 gene. 

Any efforts to target such mechanisms, including small molecules targeting RNA or modifying RNA processing pathways, may incidentally interact with the functions of SNORD116-30.

### 4. Pathways and Biological Processes
SNORD116-30 is primarily involved in:
- **Ribosome Biogenesis**: It plays an essential role in the processing and modification of pre-rRNA in nucleoli, contributing to the formation of functional ribosomal subunits.
- **RNA Methylation**: Specifically, it guides methylation of rRNA, which is crucial for correct ribosomal assembly and function.
- **Post-Transcriptional Modification**: As a snoRNA, it functions in the broader context of RNA maturation and modification, which is crucial for the regulation of gene expression.

Additional biological processes may include:
- Regulation of gene expression,
- Maintenance of cellular stress responses,
- Contributions to cellular aging and metabolism, although detailed studies linking these directly to SNORD116-30 are still ongoing.

Overall, while SNORD116-30 is primarily understood within the context of ribosomal function, its contributions to broader biological processes and potential associations with diseases make it a relevant gene for further study within the fields of genomics and bioinformatics.