### NAALADL2-AS3 Gene Overview

**Gene Symbol**: NAALADL2-AS3
**NCBI Summary**: NAALADL2-AS3 is a long non-coding RNA (lncRNA) gene which may be involved in various biological processes. 

### 1. Associated Genes
While the summaries provided do not specify additional associated genes, lncRNAs often have interactions or relationships with various protein-coding genes. For NAALADL2-AS3, potential associated genes might arise from co-expressed datasets or in contexts such as:

- **NAALADL2**: As a neighboring gene, it may show a co-expression relationship.
- **Other lncRNAs**: Relationships with other lncRNAs in the same regulatory networks. 
- **Protein-coding genes involved in neuroprotection**: Studies may have shown associations with genes linked to neurodegenerative pathways (like **APP, PSEN1, PSEN2**), but specifics depend on further investigation into expression profiles.

### 2. Aging and Age-Related Diseases
There is increasing interest in the role of lncRNAs in aging processes and age-related diseases. For NAALADL2-AS3:
- **Neurodegenerative Diseases**: Given its proximity to the NAALADL2 gene, which has been implicated in neurodegenerative diseases like Alzheimer’s disease, this lncRNA may also play a role in similar pathways.
- **Age-related Cellular Changes**: LncRNAs are known to regulate gene expression during aging processes; therefore, NAALADL2-AS3 might impact senescence or cellular stress responses.

### 3. Drug Interactions
As of now, no specific drugs or drug classes are documented to directly interact with the NAALADL2-AS3 gene. However, potential avenues of research could be:
- **Neuroprotective agents**: Since the gene may be implicated in neural processes, researching neuroprotective drugs (such as donepezil or memantine) could yield insights into indirect interactions.

### 4. Pathways and Biological Processes
NAALADL2-AS3 is implicated in several biological processes:
- **Gene Regulation**: As an lncRNA, it may influence transcriptional regulation or chromatin remodeling.
- **Neurodevelopment**: Potential implications in neuronal differentiation and development.
- **Response to Stress**: lncRNAs often play roles in stress response pathways.

Further pathways that might involve NAALADL2-AS3 could be explored through systems biology approaches, including:
- **Neurotransmitter signaling pathways**: Impacts on pathways that involve neurotransmitter synthesis or regulation, relevant in the context of neurological function.
- **Transcriptional regulation pathways**: Involvement in broader transcriptional networks affecting gene expression by modulating transcription factors.

### Conclusion
The NAALADL2-AS3 gene is an intriguing subject within the domains of genetics and bioinformatics, particularly because of its potential implications for neurobiology and aging. Further research into its exact roles, associated genes, interactions with drugs, and involvement in specific pathways and processes is necessary to fully elucidate its function and relevance in health and disease.