### NOM1 Gene Overview

**Gene Symbol**: NOM1  
**Location**: Human Chromosome 6  
**Function**: The NOM1 gene encodes a protein that plays a crucial role in intracellular processes, particularly in targeting the protein PPP1CA (protein phosphatase 1 catalytic subunit alpha) to the nucleolus, a substructure within the nucleus important for ribosome biogenesis and RNA processing.

### 1. Associated Genes
While the summaries provided do not specify associated genes, NOM1 is known to have interactions with several genes involved in nucleolar function and cellular signaling. Some related genes include:

- **PPP1CA**: Directly related as it encodes the protein that NOM1 targets.
- **NPM1**: Nucleophosmin, involved in ribosomal RNA processing and transport.
- **RPS29**: Ribosomal protein involved in protein synthesis.
- **DDX5**: Involved in pre-mRNA splicing and ribonucleoprotein assembly.

### 2. Aging and Age-related Diseases
There is limited direct evidence linking NOM1 specifically to aging or age-related diseases in the available literature; however, given its involvement in nucleolar function and PPP1CA targeting, it could contribute indirectly via:

- Cellular senescence: The regulation of nucleolar activity is critical for cell growth and proliferation, which may be influenced by NOM1 as cells age.
- Age-related conditions: Alterations in nucleolar function and PPP1CA activity have been implicated in diseases such as Alzheimer's and other neurodegenerative conditions, suggesting that NOM1 may play a role in the pathology of such diseases.

### 3. Drug Interactions
Currently, there are no specific drugs or drug classes that have been conclusively linked to direct interaction with NOM1 as per the latest data. However, given its role in cellular signaling and nucleolar function, it may be indirectly affected by:

- **Antineoplastic agents**: Drugs that target rapid cell division may influence pathways involving nucleolar regulation.
- **Immunomodulatory drugs**: Since nucleolar function can impact immune cell activity and signaling pathways.

Further research is needed to elucidate any specific pharmacological interactions.

### 4. Pathways and Biological Processes
NOM1 is involved in several crucial biological pathways and processes, including:

- **Ribosome Biogenesis**: It contributes to the assembly and maturation of ribosomes within the nucleolus.
- **Protein Dephosphorylation**: As it modulates PPP1CA localization, it is indirectly involved in signaling pathways that rely on dephosphorylation mechanisms.
- **Cell Cycle Regulation**: Through its interactions with nucleolar proteins and phosphatases, NOM1 may influence cell cycle progression.

**Associated Pathways**:
- **Nucleolar Function and Organization**: Including rRNA synthesis and processing.
- **Cell Cycle Control**: Influencing the activity of cyclins and cyclin-dependent kinases.
- **Stress Response Pathways**: Potentially involved in cellular responses to various stresses due to its role in nucleolar integrity and activity.

### Conclusion
The NOM1 gene is integral to cellular processes involving ribosome biogenesis and protein regulation. While direct associations with aging and drugs are limited, its role in important biological pathways suggests it may have broader implications in cell biology and disease pathology. Further research will be necessary to deepen our understanding of its functions and associations.