The **THBS4-AS1** gene, also known as **THBS4 antisense RNA 1**, is an lncRNA (long non-coding RNA) located on the human chromosome 1. Here are more details regarding this gene, along with the other requested insights:

### 1. Associated Genes
While the provided summaries may not list additional genes, **THBS4-AS1** is positioned adjacent to the **THBS4** gene, which encodes the thrombospondin-4 protein. lncRNAs often exhibit regulatory interactions with nearby genes. In some studies, it has also been implicated in the modulation of genes involved in angiogenesis and inflammation. However, specific additional genes directly associated with **THBS4-AS1** are not extensively detailed in current literature.

### 2. Aging and Age-Related Diseases
Research indicates that lncRNAs, including **THBS4-AS1**, may have roles in various biological processes, including those related to aging. While direct associations with specific age-related diseases are less well-defined for **THBS4-AS1**, lncRNAs are increasingly recognized in the context of neurodegenerative diseases, cardiovascular conditions, and cancer, all of which exhibit aspects of aging. The expression of certain lncRNAs can correlate with aging processes in cells, and alteration in their expression has been observed in various age-related disorders.

### 3. Drug Interactions
As of the latest updates, there are no specific drugs or drug classes definitively known to interact directly with **THBS4-AS1**. However, as research progresses, any lncRNA can be implicated indirectly through its associations with signaling pathways or cellular processes that may be targeted by pharmacological agents. It's advisable to keep an eye on emerging studies for new discoveries that may explain drug interactions or implications in therapeutic contexts.

### 4. Pathways and Biological Processes
**THBS4-AS1** has been suggested to play roles in various biological processes, including:
- **Cellular Response to Stress:** Some studies show its involvement in modulating responses to cellular stresses.
- **Angiogenesis and Vascular Formation:** Given its proximity to the thrombospondin-4 gene, it may influence processes relevant to vascular biology.
- **Inflammation:** It has potential roles in inflammation pathways, which could relate to chronic diseases associated with aging.

### Summary
The **THBS4-AS1** gene is an interesting candidate for research in both gene regulation and its potential implications in aging and related diseases. Although specific connections are still being elucidated, the study of lncRNAs like **THBS4-AS1** is an emerging field that may provide insights into complex biological processes and therapeutic targets.

Please consult the latest research articles and databases for any updates on associations, pathways, or drug interactions related to **THBS4-AS1**.