The RTL1 gene, also known as "Retrotransposon-like 1," is a well-studied gene primarily due to its role in imprinted gene expression and its involvement in developmental processes.

### 1. Associated Genes
While the summaries provided do not name specific associated genes beyond those involved in the antisense transcript regulation (potentially including other imprinted genes), RTL1 is interconnected within the imprinted gene network, often in association with other genes on the 14q32 imprinted locus. These genes include but are not limited to:
- **MEG3 (Maternally Expressed Gene 3)**: A long non-coding RNA with regulatory functions.
- **DLK1 (Delta-like 1)**: An imprinted gene involved in cellular differentiation.
- **PEG10 (Paternally Expressed Gene 10)**: Another imprinted gene important in development.
- **SNRPN (Small Nuclear Ribonucleoprotein N)**: Known for its role in the Prader-Willi and Angelman syndromes.

### 2. Aging and Age-Related Diseases
As of the latest data up to October 2023, RTL1 itself has not been directly linked to aging or specific age-related diseases in a comprehensive manner. However, the imprinted genes, in general, have been associated with various developmental syndromes and could have implications in tumorigenesis and growth disorders. It is worth noting that imprinted gene expression can be influenced by epigenetic changes, which are associated with aging.

### 3. Drug Interactions
There are no specific drugs or drug classes consistently documented as interacting directly with RTL1. However, given its involvement in cellular pathways such as angiogenesis and placental development, drugs targeting these pathways, such as anti-angiogenic therapies (e.g., Bevacizumab) may indirectly impact processes where RTL1 plays a role.

### 4. Pathways and Biological Processes
RTL1 is involved in several key biological processes and pathways:
- **Angiogenesis**: It is critical for endothelial cell function and maintenance of fetal capillaries, which is significant during placental development.
- **RNA Interference**: As noted, the expression of RTL1 is regulated by an overlapping antisense transcript that incorporates microRNAs, thereby participating in post-transcriptional regulation.
- **Imprinted Gene Regulation**: RTL1 contributes to the wider process of genomic imprinting, which is crucial for normal fetal development and placental function.

Understanding the full impact of the RTL1 gene requires ongoing research, especially regarding its interactions within the larger framework of imprinted genes and their regulation and function during development and in pathophysiology.