**TTC28-AS1 Gene Overview**

The TTC28-AS1 gene, often referred to as a long non-coding RNA (lncRNA), is situated on chromosome 1. This gene is categorized as an antisense RNA, meaning it transcribes a sequence complementary to that of its partner gene, possibly influencing the regulation of gene expression through various mechanisms. 

**1. Associated Genes:**
While specific associations may vary by research, there are certain genes that have been shown to have relationships with TTC28-AS1 in different contexts, including:
- **TTC28**: The direct sense counterpart of TTC28-AS1, with potential regulatory interactions.
- **PTEN**: In some studies, long non-coding RNAs have been implicated in the regulation of tumor suppressor genes such as PTEN.
- **miRNA genes**: TTC28-AS1 may interact with certain microRNAs, impacting their regulatory functions on target genes.

**2. Aging and Age-Related Diseases:**
Research into TTC28-AS1 is still emerging, but there are indications that lncRNAs play a role in aging and related diseases:
- **Cancer**: LncRNAs, including TTC28-AS1, are increasingly recognized for their role in oncogenesis and tumor progression. Changes in the expression of lncRNAs like TTC28-AS1 could be linked to age-related increases in certain cancers.
- **Cardiovascular Diseases**: There is emerging research suggesting that lncRNAs, possibly including TTC28-AS1, may be involved in processes related to cardiovascular health, potentially influencing age-related cardiac conditions.

**3. Drug Interactions:**
As of the latest data, there are no specific drugs or drug classes that are directly associated with TTC28-AS1. However, it is worth noting that lncRNAs can influence the pharmacodynamics of certain therapies, especially in cancer. Research into drug interactions is ongoing and may reveal potential relationships in the future.

**4. Pathways and Biological Processes:**
TTC28-AS1 may be involved in several biological processes, primarily through its regulatory roles. Potential involvement includes:
- **Gene Expression Regulation**: Being an lncRNA, it may impact the transcriptional landscape by interacting with chromatin-modifying complexes.
- **Cell Proliferation and Differentiation**: There is evidence that lncRNAs influence pathways related to cellular growth and differentiation.
- **Cancer Pathways**: As a potential regulator of oncogenes and tumor suppressor genes, TTC28-AS1 may be implicated in various signaling pathways associated with cancer development and progression.

Further research is needed to elucidate the precise roles of TTC28-AS1 in cellular mechanisms, its relationships with other genes, and its implications in aging and diseases. Continual advancements in genomics and molecular biology will likely enhance our understanding of its functional contributions.