### LINC00373 Gene Overview

**Gene Symbol**: LINC00373

**Type**: Long Intergenic Non-Protein Coding RNA (lncRNA)

LINC00373 is a long non-coding RNA located on chromosome 14 in humans. Like many lncRNAs, LINC00373 may play roles in the regulation of gene expression and can be involved in various biological processes through its interactions with proteins and microRNAs.

#### 1. Associated Genes
LINC00373 has been implicated in a variety of biological contexts, including potentially regulating or associating with several different genes. Some observations from various studies indicate interactions or associations with genes such as:

- **MYC**: A well-known oncogene involved in cell growth and proliferation.
- **TP53**: A crucial tumor suppressor gene that regulates the cell cycle and prevents cancer formation.
- **CDK6**: Part of the cyclin-dependent kinase family and plays a significant role in controlling cell division.

#### 2. Aging and Age-Related Diseases
Research has indicated associations between lncRNAs and aging or age-related diseases. While specific studies directly linking LINC00373 to these processes may be limited, its interaction with key regulators of cellular processes like MYC and TP53 suggests that it could play a role in cancer biology, which is often associated with aging. 

In particular, disturbances in lncRNA expression patterns have been implicated in:

- **Cancer**: Altered expression of LINC00373 may disrupt regulatory pathways involving cell cycle control, potentially highlighting its role in age-related cancers.
- Potential interactions in senescence-associated pathways, though detailed mechanisms are still under investigation.

#### 3. Drug and Drug Class Interactions
As of the latest data (up to October 2023), there is no direct evidence linking specific drugs or drug classes with LINC00373. However, given its potential roles in cancer biology, it is reasonable to suggest that treatments targeting pathways influenced by LINC00373 (e.g., chemotherapy agents targeting MYC or agents that restore p53 activity) may indirectly relate to this lncRNA.

#### 4. Pathways and Biological Processes
LINC00373 is involved in several biological processes and pathways, primarily:

- **Regulation of Gene Expression**: As with many lncRNAs, LINC00373 may influence the transcriptional regulation of adjacent or distant genes.
- **Cell Cycle Regulation**: Potential involvement in pathways orchestrating the progression of the cell cycle through its interactions with oncogenes and tumor suppressors.
- **Cancer Pathways**: Its interactions suggest contributions to pathways related to oncogenesis and tumor progression, particularly due to associations with MYC and TP53.

In summary, LINC00373 is a long non-coding RNA with potential roles in gene regulation, cell cycle control, and cancer biology, though its specific functions and interactions necessitate further investigation. The exploration of its association with aging or age-related diseases remains an intriguing area of research.