### SNORD114-6 Gene Overview

**Gene Symbol:** SNORD114-6  
**Gene Type:** Small nucleolar RNA (snoRNA)  
**Location:** Chromosome 14q22 (human)  
**Function:** SNORD114-6 is part of the SNORD114 family of small nucleolar RNAs, which are primarily involved in the modification of ribosomal RNA (rRNA) and have roles in nucleolar function and pre-rRNA processing.

### Associated Genes
While specific mentions of associated genes may not always be listed, SNORD114-6 is known to be part of a larger family of snoRNAs (e.g., SNORD114-1 to SNORD114-17) which may have overlapping functions or regulatory effects. Other genes potentially associated with this snoRNA could include:

- **RPL genes**: Genes encoding ribosomal proteins, as snoRNAs often act on rRNA modifying these proteins.
- **Genes in the imprinted region:** The SNORD114 genes are located within a genomic imprinting region where parent-specific expression patterns might interact with various genes.

### Aging and Age-Related Diseases
- **Potential Roles in Aging:** While direct studies linking SNORD114-6 to aging are limited, snoRNAs in general have been implicated in the regulation of cellular senescence and the maintenance of RNA homeostasis. Changes in snoRNA levels have been observed in cellular models of aging and may be involved in age-related diseases.
- **Association with Disease:** Alterations in the expression of snoRNAs, including those in the SNORD114 cluster, have been studied concerning various diseases, including cancer. However, specific studies focusing on SNORD114-6 alone and its distinct role in aging or age-related diseases may not be well-characterized.

### Drug Interactions
There is currently limited data regarding specific drugs or drug classes that interact with SNORD114-6. Most interactions of snoRNAs, including SNORD114-6, are related to cellular mechanisms rather than direct pharmacological interactions. However, drugs targeting rRNA processing or general cellular metabolism may influence the expression or activity of snoRNAs.

### Pathways and Biological Processes
SNORD114-6, as a snoRNA, is primarily involved in:
- **rRNA Methylation:** Participating in the modification of rRNA, which is crucial for ribosome biogenesis and function.
- **Nucleolar Function:** Contributing to the nucleolar structure and functioning in the synthesis of rRNA, which is pivotal for protein synthesis in cells.
- **Gene Regulation:** As with many snoRNAs, there may be potential regulatory roles in gene expression, although specific details for SNORD114-6 may not be fully elucidated.

### Summary
In conclusion, SNORD114-6 is a small nucleolar RNA with essential roles in ribosomal RNA modifications and nucleolar functions. Its implications in aging and association with other genes remain areas for further research, along with a lack of specific interactions with drugs that is typical of snoRNAs. Understanding the broader context and mechanisms of snoRNAs continues to be a pertinent area of bioinformatics and genetics research.