### TMEM235 Gene Overview

**Gene Symbol**: TMEM235  
**Predicted Location**: Cytoplasm and apical plasma membrane  
**Protein Characteristics**: N-glycosylated  

### Additional Genetic Associations

While specific associations of TMEM235 with other genes are limited in the available literature, a few genes might be involved in the same pathways or biological processes, including:

1. **TMEM237** - Similarity in family and potential functional association.
2. **TMEM16** Family - Involved in membrane transport processes, potentially linked to TMEM235 function.
3. **MPD (Multiple Phosphodiesterase)** - This gene family can be involved in pathways where TMEM235 may play a role, given shared tissue-specific expression profiles.

### Aging and Age-Related Diseases

As of the latest information:

- **Aging Correlations**: There is limited information specifically correlating TMEM235 with aging. However, abnormal cell membrane processes can be linked to age-related cellular dysfunction.
- **Age-related Diseases**: While direct associations with specific age-related diseases have not been firmly established in the literature, mutations or dysregulations in membrane proteins, such as TMEM235, could hypothetically contribute to conditions like neurodegenerative diseases due to their roles in membrane stability and signaling.

### Drug Interactions

Currently, there is no well-documented evidence of specific drugs or drug classes known to interact directly with TMEM235. However, as TMEM235 is a membrane protein, it could theoretically be affected by compounds that target membrane integrity or glycosylation processes, warranting further exploration in pharmaceutical research.

### Pathways and Biological Processes

TMEM235 is implicated in several pathways and biological processes:

1. **Cell Membrane Structure and Function**: Due to its predicted localization in the plasma membrane, it may play a role in maintaining membrane integrity and function.
   
2. **N-Glycosylation Pathways**: The N-glycosylation of TMEM235 suggests its involvement in protein folding, stability, and cell signaling through glycosylation-dependent interactions.
   
3. **Signal Transduction**: While specific pathways are not definitively assigned, the role of TMEM proteins often intersects with signal transduction processes affecting cellular responses.

4. **Developmental Processes**: Membrane proteins typically play crucial roles in cellular adhesion and signaling during development stages.

Further research is warranted to fully elucidate the roles of TMEM235 in specific biological processes, its associations with other genes, and its interactions with drugs or specific treatments.