### RNA5SP103 Gene Overview

**Gene Symbol**: RNA5SP103  
**Description**: RNA5SP103 is a gene that encodes a small nucleolar RNA (snoRNA), which is primarily involved in the process of methylation and pseudouridylation of rRNA (ribosomal RNA). snoRNAs are part of a class of non-coding RNAs that play essential roles in the maturation and processing of rRNAs.

### 1. Associated Genes
RNA5SP103 is known to be part of various gene clusters that produce multiple small nucleolar RNAs. While specific relationships to other individual genes are not extensively documented, snoRNAs like RNA5SP103 often share genomic neighborhoods with other snoRNAs and genes involved in ribosomal biogenesis. Genes associated with the processing of rRNA and ribosome assembly such as RNU5B (which encodes U5 snoRNA) may be considered associated due to their related functions in RNA processing.

### 2. Aging and Age-Related Diseases
As of my last update, there is limited direct research linking RNA5SP103 specifically to aging or age-related diseases. However, it's known that the overall dysregulation of snoRNAs and ribosome biogenesis can affect cellular function and has been implicated in various age-related dysfunctions, potentially leading to a decline in proteostasis and cellular performance as seen in aging. Additionally, changes in snoRNA expression profiles have been associated with certain cancers and neurodegenerative diseases, but any specific role of RNA5SP103 itself remains unclear.

### 3. Drug Interactions
Currently, no specific drugs or drug classes have been documented to interact directly with RNA5SP103. Given its role as a non-coding RNA involved in ribosomal function, potential indirect interactions could occur through agents that affect ribosome biogenesis or modification; however, these are not well-characterized.

### 4. Pathways and Biological Processes
RNA5SP103 is primarily involved in:

- **Ribosome Biogenesis**: As a snoRNA, RNA5SP103 contributes to the maturation of rRNA by guiding modification proteins, which methylate or modify uridines in rRNA.
- **Non-Coding RNA Processing**: Involved in the processing and functionality of rRNA within the nucleolus.
- **Gene Regulation**: Small nucleolar RNAs can play roles in regulating other RNA molecules, although specific regulatory targets for RNA5SP103 have not been distinctly outlined in the literature.

### Summary
RNA5SP103 is a small nucleolar RNA that contributes to rRNA processing and modification. Limited direct associations exist with aging or specific diseases, and interactions with drugs or pathways have not been extensively documented. Overall, snoRNAs are crucial in cellular metabolic processes, particularly in ribosome functionality, which can indirectly influence various biological and pathological conditions. Further research is needed to fully elucidate the specific roles and implications of RNA5SP103 in health and disease.