The HNRNPCL3 gene (Heterogeneous Nuclear Ribonucleoprotein C-Like 3) is a member of the RRM (RNA Recognition Motif) HNRPC family, specifically belonging to the RALY subfamily. Below, I elaborate on various aspects associated with HNRNPCL3, including its gene associations, relevance to aging, drug interactions, and pathways.

### 1. Associated Genes
While specific interacting genes might not be explicitly summarized, HNRNPCL3 is known to be part of a larger family of heterogeneous nuclear ribonucleoproteins (hnRNPs), which generally function in RNA processing. Other genes associated with hnRNP functions that may interact or share pathways include:

- **HNRNPA1**: Heterogeneous nuclear ribonucleoprotein A1
- **HNRNPH1**: Heterogeneous nuclear ribonucleoprotein H1
- **HNRNPC**: Heterogeneous nuclear ribonucleoprotein C
- **RALA**: A GTPase that may play a role in RNA transport processes.

### 2. Aging and Age-related Diseases
Currently, specific literature directly linking HNRNPCL3 to aging or age-related diseases is limited or not well-characterized. However, members of the hnRNP family, including HNRNPCL3, are involved in processes such as mRNA splicing, transport, and stability—all of which can influence cellular function and contribute to aging processes at a molecular level. Dysregulation of RNA-binding proteins has been implicated in various age-related conditions and diseases, including neurodegeneration and cancer.

### 3. Drug Interactions
There are no specific known drugs or drug classes that directly interact with HNRNPCL3. However, given its role in RNA processing, it may be indirectly affected by drugs that influence RNA metabolism or spliceosome function. General research into hnRNPs can sometimes surface compounds that impact their functions, often within the context of cancer therapies or treatments targeting RNA processing disorders.

### 4. Pathways and Biological Processes
HNRNPCL3 is involved in several critical biological processes and pathways, including:

- **RNA Splicing**: Participating in the splicing of pre-mRNA, crucial for the proper maturation of mRNA.
- **RNA Processing**: Involving the maturation of different types of RNA (mRNA, rRNA, etc.) and forming ribonucleoprotein complexes.
- **Nuclear Functions**: Involvement in processes that take place in the nucleus including transcription regulation, mRNA transport out of the nucleus, and stability of RNA.
- **Cellular Response to Stress**: Including cellular processes that respond to various cellular stresses that might affect RNA integrity and function.

### Summary
HNRNPCL3 is an important RNA-binding protein playing vital roles in RNA processing, with significant implications for gene regulation. While concrete associations with aging and drugs remain underexplored, its involvement in molecular pathways positions it as a relevant protein in cellular functions pertinent to health and disease. Ongoing research may shed further light on these aspects and elucidate its potential relevance in age-related disorders.

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