### KRT18P67 Gene Overview

**Gene Symbol**: KRT18P67

**Description**: KRT18P67 is a pseudogene related to the keratin 18 (KRT18) gene, which is part of the type I keratin family. Keratins are key structural proteins in epithelial cells and are involved in various cellular functions, including resilience to mechanical stress.

### 1. Associated Genes
Beyond KRT18P67, other related genes in the keratin family include:

- **KRT18**: The functional, non-pseudogene counterpart which is crucial for the integrity of hepatocytes and epithelial cells.
- **KRT8**: Works in tandem with keratin 18 in forming intermediate filaments in various epithelial tissues.
- **KRT19**: Often co-expressed with KRT18 in epithelial cells, critical in developmental and homeostatic processes.
- **KRT7**: Another type I keratin involved in the integrity and function of various tissues.

Other associated genes may include those involved in keratinization, cell signaling pathways, and cytoskeletal integrity.

### 2. Aging or Age-Related Diseases
While KRT18P67 itself is a pseudogene and might not have direct roles in age-related conditions, its parent gene KRT18 is known to be involved in:

- **Cellular Stress Response**: Changes in keratin expression, including KRT18, have been noted in aging tissues and can correlate with cellular resilience.
- **Age-Related Diseases**: Altered expression of keratin genes can be linked to diseases like liver fibrosis and other epithelial cancers. In the context of aging, keratin 18 levels have been evaluated as biomarkers for apoptosis and tissue integrity, which can be crucial in understanding age-related diseases.

### 3. Drug or Drug Classes Interactions
As KRT18P67 is a pseudogene, there are no known direct interactions with drugs or drug classes. However, since KRT18 is vital in epithelial cell function, drugs affecting keratinocyte function such as:

- **Chemotherapeutic agents**: Targeting fast-dividing cells can also indirectly affect keratin-based pathways.
- **Anti-inflammatory drugs**: Might impact keratin expression during epithelial repair processes.

### 4. Pathways and Biological Processes Involvement
While KRT18P67 itself may not be directly involved in biological pathways due to its pseudogene classification, its associated functional gene, KRT18, participates in:

- **Keratinization**: Necessary for skin and other epithelium formation.
- **Cell Cycle Regulation**: Keratin 18 is known to play a role in the regulation of apoptosis and the cell cycle in epithelial cells.
- **Response to Stressors**: Keratins, including KRT18, are involved in the cellular response to mechanical and oxidative stress.

### Summary
KRT18P67, as a pseudogene, does not exhibit functional capabilities but is part of the broader keratin gene family where functional partners play significant roles in cellular structure and functions related to aging and disease. Further research may unveil more about the implications of its expression patterns, particularly in connection with the actual keratin encoding genes.