### CEP104 Gene Overview

**Gene Symbol**: CEP104  
**Function**: Encodes a centrosomal protein essential for ciliogenesis and maintaining the structural integrity of ciliary tips. The protein has multiple domains and structural features supportive of its role in cilia function.

### 1. Associated Genes

While specific genes that directly interact with CEP104 may not be explicitly indicated in the summaries you provided, the following genes are often mentioned in the context of ciliogenesis and related pathological conditions, particularly Joubert syndrome:

- **ARL13B**: Implicated in cilia maintenance and function. 
- **INPP5E**: Known for its role in ciliary signaling pathways.
- **IFT88**: Involved in intraflagellar transport essential for cilia formation.
- **KIF3A**: A kinesin motor protein required for ciliary transport.

### 2. Details Related to Aging or Age-Related Diseases

Currently, specific age-related diseases directly linked to the CEP104 gene are not well established in the literature. However, given its role in ciliogenesis, it may have implications in conditions associated with cellular senescence and functional decline of cilia, which are often observed in aged cells. Ciliary dysfunction has been related to various aging-associated disorders, including:

- **Neurodegenerative diseases**: Such as Alzheimer’s disease, where cilia have been suggested to play a role in cellular signaling and clearance of toxic proteins.
- **Cardiovascular diseases**: Recent studies also suggest that defects in cilia can influence vascular health.

### 3. Drug or Drug Classes that Interact with CEP104

As of the current knowledge cutoff, there are no specific drugs or drug classes directly known to interact with CEP104. Nonetheless, as research evolves, it is important for scientists and clinicians to explore potential therapeutic avenues targeting pathways associated with ciliary function or gene expression modulations. Treatments for syndromes like Joubert syndrome may arise from investigations related to gene therapy, signaling modulators, and potentially targeted small molecules if they can restore normal ciliary function.

### 4. Pathways and Biological Processes

The CEP104 gene is involved in several critical biological processes, including:

- **Ciliogenesis**: The development of cilia from basal bodies and their elongation.
- **Ciliary assembly**: The underlying processes leading to the incorporation of proteins essential for ciliary structure.
- **Cilium organization**: Maintaining cilia structure which is vital for numerous cellular signaling pathways.
- **Signal transduction**: Involvement in pathways mediated by cilia in response to extracellular signals.

Additionally, CEP104 may be part of broader pathways related to the cell cycle and organelle organization, considering its location and function at centrosomes.

### Conclusion

Understanding the CEP104 gene is pivotal for grasping how ciliary defects can lead to diseases such as Joubert syndrome. Further research is warranted to explore its connections to aging and potential therapeutic targets, as well as elucidate the pathways in which this gene plays a critical role.