The ADRM1 gene (Adhesion Regulating Molecule 1) encodes a protein that plays a critical role in the 26S proteasome, a multi-subunit complex responsible for the ATP-dependent degradation of ubiquitin-tagged proteins. Below are additional details related to your request:

### 1. Associated Genes
ADRM1 has been linked with several other genes that may be involved in similar pathways or related functions. Some of the prominent genes include:
- **PSMD14**: A component of the proteasome lid that interacts directly with ADRM1.
- **UCHL5**: A deubiquitinating enzyme that works with ADRM1.
- **UBE2L3**: A ubiquitin-conjugating enzyme that may influence ubiquitination pathways related to ADRM1.
- **CMAH**: Suggests involvement in cellular adhesion processes.

### 2. Aging and Age-Related Diseases
Research indicates that the proteasome, which includes ADRM1, is critical for maintaining protein homeostasis, which tends to decline with age. Dysregulation of proteins involved in the proteasome can contribute to several age-related diseases, such as:
- **Neurodegenerative diseases**: Alterations in protein degradation pathways are often observed in conditions like Alzheimer's and Parkinson's disease.
- **Cancer**: Increased expression of ADRM1 has been associated with the progression of various cancers, suggesting a dual role in cellular aging and oncogenesis.

### 3. Drug Interactions
While specific drugs targeting ADRM1 directly may not be well-documented, several broader drug classes that alter proteasome function may influence ADRM1's activity indirectly:
- **Proteasome inhibitors**: Such as bortezomib and carfilzomib, are known to inhibit the proteasome, affecting its overall function and potentially altering ADRM1 activity.
- **Antineoplastic agents**: Many cancer therapies involve mechanisms that interact with the ubiquitin-proteasome system, indirectly influencing ADRM1 activity and its associated pathways.

### 4. Pathways and Biological Processes
ADRM1 is involved in several critical pathways and biological processes, including:
- **Proteasomal degradation**: As a receptor for ubiquitin-tagged proteins, ADRM1 plays a central role in selective protein degradation.
- **Cell cycle regulation**: By controlling the levels of cyclins and other regulatory proteins through the proteasomal degradation pathway.
- **Apoptosis**: By degrading pro-survival factors and facilitating programmed cell death.
- **DNA damage repair**: The protein helps regulate the degradation of factors involved in cellular response to DNA damage.

Overall, ADRM1 is a significant player in maintaining cellular homeostasis, and its dysregulation can have profound implications in aging, disease mechanisms, and therapeutic interactions. Further studies may elucidate its exact molecular functions and pathways more comprehensively.