The KAT14 gene, also known as KAT14 (Lysine Acetyltransferase 14), encodes a protein that is involved in the regulation of gene expression through acetylation of histone proteins. Here are further details regarding its associations and interactions:

### 1. Associated Genes:
While specific genes associated with KAT14 were not explicitly mentioned in the summaries, it is known that KAT14 interacts with several other proteins, mainly due to its part in the ATAC complex and its interaction with CSRP2. In broader contextual studies, KAT14 may also show enhanced or impaired interaction with genes involved in:

- **Chromatin remodeling**: Genes like *BRG1* and *SWI/SNF* complexes due to its acetyltransferase activity.
- **Cell cycle regulation**: Genes involved in the G1 and G2/M checkpoint, such as *CCND1* (Cyclin D1).
- **DNA repair mechanisms**: Interactions may occur with *TP53* in the context of stress response due to altered chromatin states.

### 2. Aging and Age-Related Diseases:
While specific age-related information on KAT14 is limited, histone acetylation is generally involved in the regulation of genes associated with aging and longevity. Dysregulation of histone acetylation has been implicated in:

- **Cancer**: The alteration in KAT14 activity may impact tumor suppressor genes or oncogenes contributing to various cancer types.
- **Neurodegenerative diseases**: Acetylation dynamics can affect histone modification patterns, potentially influencing genes linked to Alzheimer's disease.
- **Metabolic disorders**: Changes in KAT14 activity could influence metabolic genes that are subject to acetylation, which is critical in the aging process.

### 3. Drug Interactions:
As of the latest update, specific drugs interacting directly with KAT14 are not prominently listed. However, broadly speaking, histone acetyltransferase inhibitors, which may work on multiple KAT proteins, can indirectly affect KAT14 activity. Some drug classes to consider include:

- **HDAC inhibitors**: Since these drugs modulate histone acetylation, they can influence the activity of acetyltransferases like KAT14:
   - Vorinostat
   - Romidepsin
- **Anticancer agents**: Some compounds targeting cellular pathways involved in cell cycle regulation may similarly affect KAT14 through indirect pathways.

### 4. Pathways and Biological Processes:
KAT14 is involved in several critical biological processes and pathways, including:

- **Histone Acetylation**: KAT14, as part of the ATAC complex, plays a role in adding acetyl groups to histones H3 and H4, which leads to the regulation of gene expression.
- **Cell Cycle Regulation**: KAT14 is essential for the proper transition between the G1 and G2/M phases of the cell cycle, likely by modifying histones that control the expression of cell cycle-related proteins.
- **Gene Regulation**: Through its role in histone modification, KAT14 is implicated in the large-scale regulation of transcription.
- **Developmental Processes**: KAT14 may participate in various developmental signal transduction pathways due to its role as a protein adapter.

### Conclusion:
KAT14 is an essential gene encoding a lysine acetyltransferase that plays a pivotal role in histone modifications, thereby influencing gene expression and cellular functions, especially those related to the cell cycle. Further studies may elucidate its direct role in aging, disease, and potential therapeutic targets.