The **RASL11B** gene (Ras-Like Family 11 Member B) is a member of the small GTPase superfamily and is involved in various cellular signaling processes. Below is a detailed overview based on your request:

### 1. Associated Genes
While specific interactions can depend on context (such as cell types and conditions), RASL11B is generally associated with various signaling partners. Some other genes that may be implicated in the same signaling pathways or show functional relationships include:
- **TGFB1** (Transforming Growth Factor Beta 1): Involved in the TGF-β signaling pathway.
- **TGFB2** (Transforming Growth Factor Beta 2)
- **SMADs** (SMAD family members): These include SMAD2, SMAD3, and SMAD4, which are involved downstream of TGF-β receptor signaling.
- **HRAS**, **KRAS**, **NRAS**: Other members of the RAS gene family that are involved in various signaling pathways relevant to cell growth and differentiation.

### 2. Aging or Age-Related Diseases
Currently, specific associations of RASL11B with aging or age-related diseases are not extensively documented. However, given its role in TGF-β signaling—a pathway often implicated in tissue remodeling, fibrosis, and inflammation—alterations in RASL11B expression or function could potentially influence age-related processes, such as:
- **Tissue fibrosis**: Increased TGF-β signaling can promote fibrosis, which is common in age-related diseases (e.g., pulmonary fibrosis).
- **Inflammation**: Altered macrophage function may contribute to chronic inflammation associated with aging.

### 3. Drug Interactions
There are currently no specific drugs cited to interact directly with RASL11B. However, given its function in TGF-β signaling, drugs targeting this pathway (like TGF-β inhibitors) might indirectly affect RASL11B activity or expression. Some classes of drugs that may influence this pathway include:
- **TGF-β antagonists**: These may have implications in the treatment of fibrotic diseases or cancers.
- **PI3K/Akt inhibitors**: Since they often intersect with RAS signaling pathways, they might have an indirect relationship.

### 4. Involvement in Pathways and Biological Processes
RASL11B is primarily known for its role in signaling pathways, particularly those related to GTPase activity. Key biological processes and pathways include:
- **TGF-β signaling pathway**: It is involved in the modulation of TGF-β receptor signaling, impacting cell differentiation, proliferation, and apoptosis.
- **G protein signaling pathways**: As a GTPase, RASL11B is involved in signaling pathways that regulate a variety of cellular functions, including growth and migration.
- **Macrophage activation**: Its expression in macrophages suggests a role in immune responses and inflammation.
- **Cellular signaling pathways associated with development**: Given its expression patterns, it might also play roles in developmental processes.

In summary, RASL11B is a RAS-like GTPase with implications in various signaling pathways, particularly the TGF-β pathway. Its precise roles in aging and disease are still an active area of investigation, and while specific drug interactions are not well documented, its activity may be indirectly affected by agents targeting related pathways.