### LHFPL3-AS1 Gene Overview

**Gene Symbol:** LHFPL3-AS1  
**Function:** LHFPL3-AS1 (LHFPL3 Antisense RNA 1) is classified as a long non-coding RNA (lncRNA). Non-coding RNAs are not translated into proteins but play crucial roles in regulating gene expression, cellular processes, and several biological activities.

### 1. Associated Genes
While the NCBI and UniProt summaries may not list all associated genes, LHFPL3-AS1 has been indicated to be associated with various genes in studies related to its functional roles. Some genes that have been noted in the literature in relation to LHFPL3-AS1 include:

- **LHFPL3:** As the antisense RNA, LHFPL3-AS1 is directly associated with the LHFPL3 gene, which encodes a protein involved in neuronal functions.
- **RPL19, RPL22, RPL24:** Involvement in ribosomal functions, as certain lncRNAs are known to influence ribosome biogenesis and activity.

### 2. Aging and Age-related Diseases
- **Neurodegeneration:** Research has indicated potential implications of LHFPL3-AS1 in neurodegenerative diseases. While direct links to aging are still under investigation, lncRNAs are generally crucial in maintaining neuronal health and regulating pathways associated with neurodegeneration.
- **Cancer:** There may be associations with cancer-related pathways. Some studies suggest links to tumor biology, indicating that dysregulation of lncRNAs can contribute to age-related tumor progression.

### 3. Drug Interactions
Currently, there are no specific drugs or drug classes directly targeting LHFPL3-AS1 reported in major databases. However, since lncRNAs can modulate gene expression and influence cancer pathways, exploratory studies may reveal interplay where certain cancer therapeutics indirectly affect its expression.

### 4. Biological Pathways and Processes
LHFPL3-AS1 is involved in several biological processes, including:

- **Gene Expression Regulation:** Long non-coding RNAs like LHFPL3-AS1 typically regulate gene expression at various levels, including transcriptional and post-transcriptional regulation.
- **Neurodevelopment:** Given its relationship with the LHFPL3 gene, its involvement in neural functions suggests a role in processes relevant to neurodevelopment and possibly synaptic function.
- **Cell Proliferation and Apoptosis:** LncRNAs are often implicated in cell cycle regulation and apoptosis, processes crucial for maintaining cellular homeostasis.

### Conclusion
LHFPL3-AS1 is a long non-coding RNA with potential implications in neurophysiological processes and disease states, particularly in context with associated genes like LHFPL3. Its direct interactions with aging or specific drugs remain largely unexplored, signaling a need for continued research to better understand its functional roles and therapeutic potential in age-related pathologies.