### CDKN2AIPNLP3 Gene Overview

**Gene Symbol:** CDKN2AIPNLP3  
**Full Name:** CDKN2A interacting protein (CDKN2AIP) and non-coding RNA of the CDKN2A locus (NLRC3)  
**Chromosomal Location:** Located on chromosome 9.

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### 1. Associated Genes
The CDKN2AIPNLP3 gene is primarily associated with the following genes:

- **CDKN2A:** This gene encodes for a key tumor suppressor protein that plays a critical role in cell cycle regulation.
- **CDKN2B:** Also a tumor suppressor in the INK4 family, CDKN2B works similarly to CDKN2A in regulating cell proliferation.
- **ARF (CDKN2A):** The alternative reading frame protein, which is expressed from the CDKN2A locus and involved in p53 signaling.

### 2. Aging and Age-Related Diseases
While specific studies directly linking CDKN2AIPNLP3 to aging are limited, the CDKN2A locus as a whole has been noted for its association with cellular senescence and age-related pathologies. Here are some relevant points:
- **Cellular Senescence:** Genes in the INK4a/ARF locus (including CDKN2A) are implicated in the regulation of cellular senescence, a key process in aging that prevents the propagation of damaged cells.
- **Age-Related Diseases:** Alterations in expression of CDKN2A and its associated proteins have been linked with various age-related diseases, including certain cancers.

### 3. Drug Interactions
Currently, there are no specific drugs or drug classes uniquely associated with the CDKN2AIPNLP3 gene. However, as it relates to the broader functions of the INK4a/ARF locus:
- **Cancer Therapeutics:** Agents targeting pathways that involve CDKN2A, such as CDK inhibitors, may have indirect effects on the functions mediated by the CDKN2AIPNLP3 gene.
- **Anti-aging Compounds:** In investigations of compounds that modulate senescence and pathways related to cellular aging could influence gene expression of CDKN2A-related proteins.

### 4. Pathways and Biological Processes
The CDKN2AIPNLP3 gene is involved in several critical biological processes and pathways:
- **Cell Cycle Regulation:** The INK4a/ARF locus directly influences cell cycle progression by inhibiting cyclin-dependent kinases (CDKs).
- **Tumor Suppression:** As an integral part of the oncogenic signaling pathways, the expression of CDKN2AIPNLP3 may contribute to the suppression of tumor formation.
- **p53 Signaling Pathway:** Interaction with p53-related pathways through the ARF transcript, influencing apoptosis and DNA repair.
- **Senescence Induction:** Involved in the induction of cellular senescence, affecting longevity and cancer prevention.

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### Summary
The CDKN2AIPNLP3 gene is a significant player at the intersection of tumor suppression and cell cycle regulation, with implications in cellular aging and age-related diseases. Although precise drug interactions are not readily established, correlative effects may arise from its relationship with the broader CDKN2A locus and associated pathways. Further research could provide deeper insight into its functionalities and therapeutic potentials.