### LINC00664 Gene Overview

**Gene Symbol:** LINC00664

**Type:** Long Intergenic Non-Protein Coding RNA (lincRNA)

#### Summary
LINC00664 is a long non-coding RNA gene located on human chromosome 14. As a lincRNA, it is involved in gene regulation and may act in various biological processes. While it does not code for proteins, lincRNAs have been recognized for their crucial roles in regulating gene expression at multiple levels, including chromatin remodeling, transcriptional and post-transcriptional regulation.

### Associated Genes
LINC00664 has been implicated in the regulation of several genes, including but not limited to:

- **TP53**: Known for its role in tumor suppression.
- **MYC**: A gene that regulates various cellular processes including cell cycle progression and apoptosis.
- **CDK6**: A key player in cell cycle regulation.
  
Additionally, LINC00664 might be associated with various other regulatory networks influencing genes important in cancer and metabolic disorders, although specific gene associations can vary based on study context.

### Aging and Age-Related Diseases
Research has pointed toward LINC00664's involvement in cellular processes that might be linked to aging:

1. **Cellular Senescence**: Some studies suggest that alterations in lincRNA expression, including LINC00664, may be involved in the mechanisms of cellular senescence.
2. **Cancer**: There is emerging evidence that LINC00664 may play a role in tumorigenesis and could be associated with age-related cancers. Its aberrant expression has been noted in various cancer types, which often correlates with age and age-related pathways.
3. **Metabolism**: Some findings indicate potential roles for LINC00664 in metabolic regulation, which can also impact aging.

### Drug Interactions
While there are currently no specific drug interactions documented in major databases like NCBI or UniProt that directly involve LINC00664, its association with genes like TP53 and MYC indicates it could influence pathways that are relevant to various cancer therapies and metabolic drugs.

### Pathways and Biological Processes
LINC00664 is known to be involved in various biological pathways and processes:

1. **Regulation of Gene Expression**: As a lincRNA, its primary role is hypothesized to involve the modulation of transcriptional and post-transcriptional processes.
2. **Involvement in Cancer Pathways**: It has been linked to cancer-related pathways, including those mediated by oncogenes and tumor suppressor genes.
3. **Cell Cycle Regulation**: Given its association with CDK6 and other cell cycle-related genes, it may play a role in the regulation of the cell cycle.
4. **Metabolic Process Regulation**: Potential influences on metabolic pathways suggest a broader role in maintaining cellular homeostasis.

### Conclusion
In summary, LINC00664 is an important lincRNA that plays a role in various regulatory mechanisms within the cell, particularly concerning gene expression and cell cycle control. Its associations with aging and age-related diseases, as well as interactions with key oncogenes and tumor suppressor genes, suggest it could be a significant factor in cancer biology and the aging process. Further research might elucidate its potential as a therapeutic target in age-related diseases and cancer.