### SNORD82 Gene Overview

**Gene Symbol**: SNORD82  
**Alias**: This gene is a member of the small nucleolar RNA (snoRNA) family that is primarily located in the nucleolus and is involved in the modification and processing of ribosomal RNA (rRNA).

#### 1. Associated Genes
While specific associations of SNORD82 with other genes are less frequently documented, snoRNAs, including SNORD82, are often associated with a variety of genes related to ribosomal RNA synthesis and processing. Other snoRNAs may share processing pathways with SNORD82, such as:

- **RBM15**: An RNA-binding protein that may influence the processing of snoRNAs.
- **FBL**: A protein known to function in the assembly of snoRNPs that includes snoRNAs like SNORD82.
- Ribosomal protein genes: Because of its role in rRNA processing, snoRNAs, including SNORD82, typically have an indirect association with ribosomal protein genes.

#### 2. Aging and Age-Related Diseases
While direct associations between SNORD82 and aging or age-related diseases may be limited in current literature, it is known that disturbances in snoRNA expression are often observed in cancers and age-related conditions. Various studies suggest that snoRNAs can be involved in the regulation of gene expression, which may have downstream effects on cellular aging, stress responses, and other processes relevant to age-related diseases. Furthermore, specific snoRNAs have been associated with conditions like:

- Alzheimer's disease: Altered expression of certain snoRNAs has been noted in neuronal tissues affected by the disease.
- Cancer: Aberrant expression of snoRNAs is often linked with various types of tumors, potentially implicating aged-related mutagenesis and DNA repair pathways.

#### 3. Drugs or Drug Classes
Currently, there are no specific drugs or drug classes directly known to interact with SNORD82. However, because it is involved in fundamental processes like RNA modification, it may be indirectly affected by treatments targeting RNA processing and gene expression pathways, such as:

- **Antisense oligonucleotides**: These might affect the levels or functions of snoRNAs, although no specific drugs targeting SNORD82 have been reported.

#### 4. Pathways and Biological Processes
SNORD82 is primarily involved in:

- **Ribosome biogenesis**: As a snoRNA, SNORD82 contributes to the processing and modification of rRNA, ensuring proper ribosome assembly which is crucial for protein synthesis.
- **rRNA methylation**: SNORD82 may be involved in guiding methyl groups to specific sites on rRNA, influencing the structural integrity and function of ribosomes.

Potential pathways include:

- **RNA processing**: Participates in various RNA maturation processes, specifically through its functions in nucleolar assembly and RNA modification systems.
- **Gene expression regulation**: By influencing rRNA processing, SNORD82 may indirectly affect the transcriptional landscape of the cell.

### Conclusion
SNORD82 is an essential component of the nucleolar machinery and plays an important role in ribosome biogenesis through its snoRNA functions. Although direct evidence linking it to aging and disease mechanisms is still emerging, its broader family links it to processes relevant for cellular health and function. Further studies may illuminate its precise roles in specific pathologies and highlight its therapeutic potential.