### CCDC157 Gene Overview

**Gene Symbol:** CCDC157  
**NCBI Gene ID:** 64716  
**UniProt Accession:** Q96KZ2

The CCDC157 gene, or "Coiled-Coil Domain Containing 157," is part of a family of genes characterized by coiled-coil domains that are typically involved in protein-protein interactions. However, the specific biological functions and roles of CCDC157 remain less well studied.

### 1. Associated Genes
While the summaries provided do not mention specific gene associations, the following related genes may be relevant based on genomic proximity or functional similarity:

- **CCDC158**: Another coiled-coil domain containing gene which may share regulatory or structural roles within the same pathways or cellular processes.
- **CCDC96**: This gene may also be associated through structural similarities and potentially overlapping functions in coiled-coil interactions.
- **CENPJ (Centromere Protein J)**: Though not a coiled-coil protein, it interacts indirectly during the processes of cell division where CCDC157 may be involved.

### 2. Aging or Age-Related Diseases
Specific research linking CCDC157 directly to aging or age-related diseases is sparse. However, genes with coiled-coil domains often play roles in cellular structure and function, which can impact:

- **Cellular Aging**: Coiled-coil proteins may be involved in maintaining cellular integrity, which could influence senescence.
- **Neurodegenerative Diseases**: Alterations in protein interactions in aging tissues might correlate with conditions like Alzheimer’s Disease, but direct evidences related to CCDC157 are still lacking in the literature.

### 3. Drug Interactions
Currently, there are no specific drugs or drug classes mentioned that interact with CCDC157 in the databases. This could be attributed to the limited characterization of the gene's functional roles, and therefore, no targeted therapies or pharmacological interactions are established.

### 4. Pathways and Biological Processes
As of the latest data, CCDC157's involvement in specific biological pathways is not well-defined. However, insights can be inferred based on its gene family:

- **Protein-Protein Interaction Pathways**: Given its coiled-coil domain structure, CCDC157 is likely involved in pathways requiring molecular scaffolding and structural integrity, such as cytoskeletal organization and cellular signaling.
- **Developmental and Cellular Processes**: It may also play a role in cellular development and maintenance, although detailed functional studies are necessary to delineate its exact contributions.
  
### Conclusion
While CCDC157 is part of a significant class of proteins, much of its functional relevance, especially in relation to aging, specific diseases, drug interactions, and biological pathways, remains to be explored. Future studies could illuminate its roles in human health and disease, particularly within aging contexts and related biochemical pathways.