CD164L2 (CD164 like 2), also known as Hematopoietic cell surface antigen CD164L2, is a gene that encodes a protein belonging to the CD164 family, which is associated with cell adhesion processes and immune responses. The gene is predicted to have an integral role in membrane structure and is involved in cytoplasmic vesicle activity.

### 1. Associated Genes:
CD164L2 could be associated with other genes involved in hematopoiesis, immune response, and cell adhesion. While specific gene interactions can vary in specific biological contexts and studies, here are a few genes that often show co-expression or functional relevance:
- **CD164** - As a member of the same family, it has a functional relationship with CD164L2.
- **CD44** - This gene plays roles in cell adhesion and migration, relevant to hematopoietic cells.
- **ITGA4 (Integrin alpha 4)** - Involved in cell adhesion and migration of hematopoietic progenitors.
- **L-selectin (SELL)** - Regulates leukocyte trafficking and homing.

### 2. Aging and Age-Related Diseases:
Research indicates that changes in gene expression associated with immune cells can be implicated in age-related diseases. While specific studies on CD164L2 in aging are limited, members of the CD164 family have been suggested to influence inflammation and immune function in aged individuals. Dysregulation of immune responses is a key factor in multiple age-related diseases, including:
- **Autoimmune diseases**
- **Chronic inflammation** 
- **Cancer** 
Changes in expression patterns of adhesion molecules like CD164L2 may correlate to alterations in cellular interactions within the immune system over time.

### 3. Drug Interactions:
Currently, there are no specific drugs or drug classes widely reported to interact directly with the CD164L2 gene or its protein product. However, because CD164L2 is involved in immune functions, drugs that modulate immune responses, such as corticosteroids, monoclonal antibodies targeting immune pathways, or therapies aimed at addressing inflammation, could indirectly affect CD164L2 activity. Further research may reveal more specific interactions in the context of diseases.

### 4. Pathways and Biological Processes:
CD164L2 is likely involved in several important biological processes and pathways, including:
- **Immune response** - The CD164 family has roles in lymphocyte and stem cell functions.
- **Cell adhesion** - Participation in pathways underlying cellular interactions in hematopoietic cells.
- **Vesicle-mediated transport** - Involvement in the transport and secretion of cellular materials.

In summary, while specific information regarding CD164L2 might be limited compared to other genes, its predicted roles in immune function, potential connections to aging, and involvement in cell adhesion processes render it a subject of continued interest in bioinformatics and genetics research. Further studies are necessary to elucidate its precise functions and significance in health and disease.