### OC90 Gene Summary

**Gene Symbol:** OC90  
**Function:** Predicted to enable calcium ion binding activity and structural molecule activity. This gene is involved in otolith mineralization and is located in the extracellular region, primarily within the extracellular matrix.

**Protein Summary:** OC90 is a major component of otoconia, which are calcium carbonate structures found in the saccule and utricle of the inner ear, crucial for balance and spatial orientation. It works in conjunction with OTOL1 to act as a scaffold for otoconia biomineralization, facilitating the sequestration of calcium and forming fibrils that contribute to the crystal structure of calcium carbonate.

### 1. Associated Genes
Besides OTOL1, which is a direct partner in the biomineralization process of otoconia, OC90 may also have associations or interactions with other genes involved in calcium metabolism, ear and vestibular system development, and extracellular matrix components. Although not exhaustive, potential associated genes could include:
- **OTOL** (related to otoconia formation)
- **COL2A1** (involved in collagen structure and function)
- **PAX2** (associated with ear development and may impact otoliths)

### 2. Aging and Age-Related Diseases
Currently, specific aging-related diseases associated with OC90 have not been conclusively determined. However, age-related decline in vestibular function, which can be influenced by otolithic structures, may implicate OC90's involvement in balance disorders seen in the elderly. Any mutations or dysregulation in OC90 could potentially contribute to vestibular dysfunction or otolithic-related conditions in aging populations.

### 3. Drug Interactions
As of the latest information available up to October 2023, there are no specific drugs or drug classes documented that directly interact with the OC90 gene/protein. However, since OC90 is involved in calcium ion regulation, it may be indirectly affected by drugs that influence calcium homeostasis, such as:
- **Calcium channel blockers**
- **Calcium supplements**
Further pharmacological studies would be necessary to elucidate any specific interactions.

### 4. Pathways and Biological Processes
OC90 is involved in several biological processes, including but not limited to:
- **Otolith Biogenesis:** Essential for the formation and maintenance of otoconia, which are critical in the inner ear for balance.
- **Biomineralization:** The process through which living organisms produce minerals, utilizing proteins such as OC90 for calcium carbonate structure formation.
- **Extracellular Matrix Organization:** Contributes to the structural organization of the extracellular matrix, pivotal for cellular scaffolding and signaling.

Overall, OC90 plays a vital role in ear physiology, particularly in balance mechanisms, and highlights the intricate interactions of proteins within the otolithic system. Further studies may reveal more about its role in wider systemic processes, aging, and potential therapeutic targets.