### SNORD114-30 Gene Overview

- **Gene Symbol**: SNORD114-30
- **Gene Type**: Small nucleolar RNA (snoRNA)
- **Function**: SNORD114-30 is part of a cluster of small nucleolar RNAs (snoRNAs) known as the SNORD114 family, which is involved in the biogenesis and modification of ribosomal RNA (rRNA). These snoRNAs are primarily localized in the nucleolus and play a critical role in guiding the methylation of rRNA and other non-coding RNAs.

### 1. Associated Genes 

SNORD114-30 is part of a larger gene cluster located on chromosome 14. Other genes in close proximity to the SNORD114 cluster include other members of the SNORD114 family such as SNORD114-25, SNORD114-26, and SNORD114-27. Although these genes share functional similarities, specific associations beyond this cluster, particularly with other genes, are less documented and may involve a variety of ribonucleoprotein complexes within the RNA processing pathways.

### 2. Aging and Age-Related Diseases

Although specific studies directly linking SNORD114-30 to aging or age-related diseases may not be abundant, snoRNAs have been implicated in various cellular processes that are crucial for maintaining cellular homeostasis, which can decline with age:

- **Ribosome Biogenesis**: The proper function of snoRNAs in processing rRNA is essential for ribosome assembly. Impairment in ribosome biogenesis has been associated with age-related decline in cellular function.
- **Cellular Longevity**: Alterations in the expression of snoRNAs have been observed in various aging processes, hinting at their potential role in regulating stress responses and cellular senescence.

Study of these associations is ongoing, and further research could clarify their significance in the context of aging.

### 3. Drug Interactions

As of the latest information, there are no specific drugs or drug classes directly associated with SNORD114-30. However, repression or modulation of snoRNA expression may influence the effectiveness of certain cancer therapies due to their role in regulating cellular growth and proliferation. 

### 4. Pathways and Biological Processes

- **Ribosomal RNA Processing**: SNORD114-30 is involved in the processing and modification of rRNA, which is critical for ribosome function.
- **Nucleolar Function**: As a member of the snoRNA family, SNORD114-30 plays an essential role in nucleolar structures' function and integrity.
- **Gene Expression Regulation**: snoRNAs can also influence mRNA stability and processing, further contributing to gene regulation.

#### Summary

SNORD114-30 is a small nucleolar RNA implicated in the maturation and modification of rRNA, playing a vital role in the proper functioning of ribosomes. While direct associations with aging and specific drugs have yet to be firmly established, the broader implications of snoRNAs in cellular processes suggest potential relevance in age-related research and pharmacogenomics.