### Gene Overview: DDX11-AS1

**Gene Symbol:** DDX11-AS1  
**Location:** Located on the human chromosome 2.

DDX11-AS1 is a long non-coding RNA (lncRNA) gene that is associated with various biological processes and has been implicated in different pathological conditions. Long non-coding RNAs like DDX11-AS1 serve crucial regulatory roles in gene expression and cellular processes.

### 1. Associated Genes

DDX11-AS1 has been found to be associated with several genes, particularly those involved in:

- **DDX11:** The gene is often located near DDX11, a gene encoding a DEAD-box helicase that is implicated in DNA repair and chromosomal stability.
- **Other adjacent genes** may include those involved in RNA and protein processing, but specific details about these would require comprehensive genome interaction studies.

### 2. Aging and Age-related Diseases

While direct associations of DDX11-AS1 with aging or age-related diseases are limited, studies have indicated potential roles of lncRNAs in:

- **Cellular senescence:** DDX11-AS1 may play a role in modulating cellular responses to stress, influencing aging processes.
- **Cancer:** LncRNAs, including DDX11-AS1, have been implicated in tumor progression and metastasis in various cancers. The regulation of cell cycle and apoptosis are critical aspects that might link this gene to age-related increases in cancer incidence.

### 3. Drug or Drug Class Interactions

Currently, specific drugs or drug classes directly interacting with DDX11-AS1 have not been well-characterized in the literature. However, it is known that:

- **Cancer therapies** may impact lncRNA expression, including DDX11-AS1. Since many lncRNAs are deregulated in cancer, ongoing research might identify potential therapeutic targets linked to these non-coding RNAs.

### 4. Pathways and Biological Processes

DDX11-AS1 has been implicated in several biological processes and pathways including:

- **Gene Regulation:** As a long non-coding RNA, DDX11-AS1 is known for its role in transcriptional regulation.
- **DNA Repair:** Its association with DDX11 suggests involvement in DNA repair pathways, crucial for maintaining genomic stability.
- **Cell Cycle Regulation:** The expression of DDX11-AS1 has been correlated with cell cycle dynamics, possibly acting as a modulator of cell proliferation.
- **Chromatin Remodeling:** DDX11-AS1 might have regulatory roles in modifying chromatin structure, impacting gene expression profiles.

### Conclusion

The DDX11-AS1 gene represents a significant area of study in the context of non-coding RNAs and their influence on gene regulation, cellular processes, and potential implications in aging and disease. Continued research will be critical to uncover the full spectrum of its biological roles and therapeutic potential.