### RNU2-65P Gene Overview

**Gene Symbol:** RNU2-65P

RNU2-65P is a pseudogene that is part of a larger family of small nucleolar RNAs (snoRNAs) and is specifically classified under the U2-type snoRNA genes. These snoRNAs are primarily involved in the modification and assembly of ribosomal RNA (rRNA) and small nuclear RNA (snRNA). As a pseudogene, RNU2-65P is believed to be a non-functional copy of a gene that has lost its ability to code for a functional product.

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### 1. Associated Genes

While specific associations may vary by study, some commonly referenced genes that may be linked with snoRNA-related pathways or processes include:

- **RNU2-1**: Another U2-type snoRNA.
- **RNU4-7**: A member of the U4 snoRNA family.
- **SNORA47**: Another member involved in rRNA processing.
  
Note: Associations are often context-dependent and may not be direct functional relationships.

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### 2. Aging and Age-related Diseases

Current research has indicated that changes in snoRNA expression levels can be associated with various age-related conditions, though specific data on RNU2-65P is limited. However, alterations in the expression of snoRNAs are implicated in:

- Age-associated declines in ribosome biogenesis, which can lead to cellular senescence.
- Potential roles in the pathogenesis of neurodegenerative diseases as alterations in RNA processing and modification can affect overall cellular health.

That said, further specific studies would be required to directly link RNU2-65P with aging or age-related diseases.

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### 3. Drug Interactions

As of the current knowledge cutoff in October 2023, there are no specific drugs or drug classes that have been documented to interact directly with the RNU2-65P gene. Pseudogenes generally are not direct targets for pharmacological agents since they do not encode functional proteins. However, insight into their regulatory roles may be gained through broader studies on RNA-targeting therapies or interventions affecting snoRNA pathways.

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### 4. Pathways and Biological Processes

While more precise associations may require targeted literature reviews and experimental validation, RNU2-65P likely participates in the following biological processes:

- **Ribosome biogenesis**: It may contribute indirectly to the processing of pre-rRNA and the maturation of rRNA.
- **rRNA modification**: As with other snoRNAs, it may play a role in guiding chemical modifications of rRNA molecules.
- **RNA metabolism**: It may influence processes related to the splicing and processing of other RNA species.

The exact functional contributions of RNU2-65P may be less direct compared to other active snoRNAs, reflecting its status as a pseudogene.

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### Conclusion

RNU2-65P represents an interesting component of the snoRNA family, holding potential relevance in RNA processing and regulation, particularly concerning ribosomal function and cellular health. Further research is needed to explore its implications in aging and disease more thoroughly.