### CENPNP1 Gene Summary

**Gene Symbol**: CENPNP1

**Overview**: The CENPNP1 gene codes for a protein that is implicated in various cellular processes, particularly those related to the cell cycle and chromosomal dynamics.

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### 1. Associated Genes
The CENPNP1 gene may interact with several other genes involved in similar pathways or processes. While specific associations might not be listed in the summaries you provided, common genes associated within the context of centromere function and chromosomal behavior often include:

- **CENPA**: Histone H3 variant that plays a role in centromere formation.
- **CENPB**: DNA-binding protein that is associated with centromeres.
- **CENPC**: A component of the CENP complex, which is vital for proper chromosome segregation.
- **CENPD**, **CENPE**, **CENPF**: Other centromere-associated proteins.

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### 2. Aging and Age-Related Diseases
Currently, there is no specific research directly linking CENPNP1 to aging or age-related diseases. However, proteins involved in centromere stability and the attachment of chromosomes are critical during cell division. Misregulation of these processes has been implicated in age-related changes, genomic instability, and diseases such as cancer. Potential indirect associations may be worth exploring in future research related to:

- **Cellular Senescence**: Defects in chromosomal dynamics may lead to cellular aging.
- **Cancer**: Altered expression or mutations in centromere proteins often correlate with tumorigenesis.

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### 3. Drug Interactions
As of the latest information, there are no specific drugs or drug classes documented to directly interact with the CENPNP1 gene. Research surrounding gene-targeted therapies is ongoing, and future findings may reveal drugs that influence CENPNP1 expression or function, particularly in cancer therapeutics targeting cell division.

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### 4. Pathways and Biological Processes
CENPNP1 is involved in several critical biological processes, including:

- **Cell Cycle Regulation**: Important for the proper progression and regulation of the cell division cycle.
- **Chromosome Segregation**: Plays a role in ensuring accurate segregation of chromosomes during mitosis.
- **Centromere Organization**: Involves processes that maintain centromere integrity and function.
- **DNA Repair Mechanisms**: While not its primary function, centromere-associated proteins may have roles in the DNA damage response.

**Key Pathways**: The most relevant pathways related to CENPNP1 likely include:

- **Cell Cycle**: Impacting S phase and mitosis specifically.
- **Mitotic Spindle Assembly**: Influences the structural formation of the spindle apparatus during cell division.

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### Conclusion
The CENPNP1 gene plays a vital role in cellular division, and while its direct connections to aging and specific diseases are not yet fully characterized, it is crucial in maintaining genomic stability and chromosomal integrity. Ongoing research may illuminate greater insights regarding its functions and potential clinical implications in age-related conditions or therapies.