### PGAM1P3 Gene Overview

**Gene Symbol**: PGAM1P3  
**Type**: Pseudogene  
**Location**: The PGAM1P3 gene is located on chromosome 10 in humans.

#### 1. Associated Genes
While PGAM1P3 is known primarily as a pseudogene of the phosphoglycerate mutase 1 (PGAM1) gene, further genomic studies indicate potential interactions or associations with several other genes, particularly those involved in metabolic pathways. However, specific associations can vary based on the context of analysis, and direct interactions might not be comprehensively documented.

**Related Genes**:
- **PGAM1**: The primary functional homolog that conveys metabolic processes.
- **PGAM2**: Another member of the PGAM family with potential relevance in glycolytic pathways.

#### 2. Aging and Age-Related Diseases
As a pseudogene, PGAM1P3 itself may not have a direct functional role. However, its proximity to functional genes like PGAM1 can suggest involvement in metabolic processes that are critical in aging and age-related diseases. Alterations in glycolysis and energy metabolism are often implicated in age-related pathologies, including age-related cognitive decline and metabolic syndromes.

Current research linking PGAM1P3 directly to aging is limited, but its associated pathways can have implications in tumorigenesis and conditions such as cancer, which show increased incidence with age.

#### 3. Drug Interactions
As PGAM1P3 is a pseudogene, there are no direct drug interactions documented specifically for it. However, pharmacological agents targeting the glycolytic pathway, in which its functional counterpart PGAM1 is involved, might indirectly relate to cellular processes influenced by PGAM1P3’s genetic context. Examples of drug classes affecting glycolysis include:

- **Metformin**: Often used in diabetes management; influences pathways linked to glycolytic metabolism.
- **Glycolytic Inhibitors**: Various investigational drugs under study for cancer treatment that may affect the inactivity or regulation of glycolysis.

#### 4. Pathways and Biological Processes
Since PGAM1P3 is a pseudogene, it does not have a directly assigned function. Nonetheless, it is likely associated with biological processes through its related functional gene PGAM1, which plays a significant role in:

- **Glycolytic Pathway**: Involvement in the conversion of 3-phosphoglycerate to 2-phosphoglycerate, essential for energy metabolism.
- **Cellular metabolism and energy production**: Implications in both normal physiological processes and pathological states such as cancer metabolism.

### Summary
In summary, PGAM1P3 is mainly recognized as a pseudogene associated with related pathways through its proximity to the functional PGAM1 gene. While evidence directly tying PGAM1P3 to aging or specific diseases is limited, its locational context suggests implications in broader metabolic functions important for health and disease as individuals age. Further research may reveal more intricate details regarding its role within genomic networks and its impact on health.