### NCCRP1 Gene Summary

**Gene Symbol**: NCCRP1  
**Location**: Cytoplasm  
**Function**: Predicted to contribute to ubiquitin protein ligase activity, involved in the positive regulation of cell population proliferation, and promotes cell proliferation.

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### 1. Associated Genes
NCCRP1 is known to be associated with various other genes, particularly in the context of specific cellular functions and pathways. While the NCBI and UniProt summaries do not specifically list associated genes, literature indicates potential associations with genes involved in cell cycle regulation, growth factor signaling, and apoptosis, such as:

- **CCND1** (Cyclin D1) - involved in cell cycle regulation.
- **EGFR** (Epidermal Growth Factor Receptor) - associated with promoting cell proliferation.
- **CMET** (MET Proto-Oncogene) - involved in cell growth and connectivity to signaling pathways.

### 2. Aging and Age-Related Diseases
Research into NCCRP1 and its roles suggests potential implications in aging and age-related diseases. Aberrant regulation of cell proliferation can lead to various age-related conditions, including:

- **Cancer**: Due to the gene's role in promoting cell proliferation, dysregulation could contribute to tumorigenesis.
- **Regenerative Decline**: As organisms age, decreased signaling efficiency from genes like NCCRP1 may impair regenerative capacity and affect tissue homeostasis.
- **Metabolic Disorders**: Altered expression has been implicated in metabolic dysregulations related to aging.

### 3. Drug Interactions
As of the latest data until October 2023, specific drug interactions with NCCRP1 have not been well-characterized in widely accessible databases. However, potential drug classes that may influence NCCRP1's activity through modulation of cell proliferation include:

- **Chemotherapeutic agents**: Due to its involvement in proliferation, drugs targeting proliferative pathways may indirectly influence NCCRP1's function, particularly in oncology.
- **Targeted therapies**: Drugs that modulate signaling pathways involved in the cell cycle (e.g., inhibitors targeting EGFR or MET) may impact NCCRP1 activity indirectly.

Further research is recommended to elucidate specific compounds or therapies that directly interact with NCCRP1.

### 4. Pathways and Biological Processes
NCCRP1 is involved in several biological processes and pathways, including:

- **Cell Cycle Regulation**: Promotes progression through various phases of the cell cycle.
- **Signal Transduction**: Involved in signaling pathways related to growth factors and oncogene signaling.
- **Ubiquitin-Mediated Proteolysis**: Contributes to protein tagging for degradation, impacting cell cycle dynamics.

Additional pathways often associated with NCCRP1's function may include:

- **MAPK Signaling Pathway**: Plays a role in cell proliferation and differentiation.
- **PI3K-Akt Signaling Pathway**: Involved in diverse cellular functions, including metabolism, proliferation, and survival.

### Conclusion
The NCCRP1 gene appears to play a significant role in regulating cell proliferation and is potentially linked to aging and age-related diseases, notably cancer. While direct drug interactions with NCCRP1 remain less clear, its involvement in broader pathways presents opportunities for therapeutic targeting. Further research is warranted to uncover specific associations and mechanisms.