### SNORD117 Gene Overview

**Gene Symbol**: SNORD117  
**Function**: SNORD117 (Small Nucleolar RNA Domain 117) is classified as a small nucleolar RNA (snoRNA), which is involved primarily in the modification and processing of ribosomal RNA (rRNA). Specifically, it is thought to facilitate the methylation of rRNA molecules, which is crucial for the proper functioning of ribosomes in protein synthesis.

### Gene Associations

While SNORD117 itself is a member of the C/D box small nucleolar RNA family, it can be associated with other genes, particularly those involved in rRNA processing and modification. However, specific genes directly regulated or strongly associated with SNORD117 may not be extensively documented in the literature. Some possible associations may include:

- **Box C/D snoRNA family**: Other snoRNAs in the box C/D family may exhibit functional interactions with SNORD117 in the rRNA modification machinery.
  
It's worth noting that association with various rRNA genes like **RPS16** (ribosomal protein S16) may be observed indirectly due to its role in rRNA processing.

### Aging and Age-Related Diseases

Research on SNORD117 in the context of aging or age-related diseases is limited, but there are some insights:

- **Cellular Stress and Aging**: Some studies suggest that snoRNAs play roles in cellular stress responses and homeostasis. Dysregulated expression of snoRNAs, including SNORD117, has been implicated in age-related changes to the ribosome and protein synthesis capacity, which could contribute to cellular aging and dysfunction.
  
- **Neurodegenerative Diseases**: Alterations in snoRNA levels, including SNORD117, have been suggested to be linked to neurodegenerative diseases. While direct evidence relating SNORD117 to specific age-related diseases is scant, the association of snoRNAs with neuronal function and stress responses suggests potential relevance.

### Drug Interactions

As of now, there are no known specific drugs or drug classes that directly interact with SNORD117. However, given its role in ribosomal function, compounds that affect ribosomal biogenesis or function may indirectly influence its activity.

### Pathways and Biological Processes

SNORD117 is involved in several biological processes:

1. **rRNA Methylation**: Functions primarily in the 2'-O-methylation of rRNA, which is critical for mature ribosome assembly and function.
2. **Ribosome Biogenesis**: Contributes to the production and maturation of ribosomal subunits, essential for translation.
3. **Regulation of Gene Expression**: Involved in the regulation of various genes through its role in modifying rRNA, impacting overall protein synthesis within cells.

### Conclusion

In summary, SNORD117 is a small nucleolar RNA involved in critical processes associated with ribosome biogenesis and rRNA methylation. Its role in aging and age-related diseases is an emerging area of research that warrants further investigation. Currently, specific drug interactions with SNORD117 are not well characterized, highlighting the need for additional studies to explore therapeutic implications.