### Summary of PPP3CB-AS1 Gene

The PPP3CB-AS1 (PPP3CB Antisense RNA 1) gene is a long non-coding RNA (lncRNA) that is associated with the PPP3CB gene, which encodes a regulatory subunit of the calcium/calmodulin-dependent phosphatase calcineurin. PPP3CB is involved in various biological processes, including T-cell activation, neuronal signaling, and cardiac hypertrophy.

### 1. Associated Genes

While the specific summaries from NCBI and UniProt may not elaborate on other associated genes, it is generally understood that lncRNAs like PPP3CB-AS1 often show co-expression or functional associations with protein-coding genes. Here are a few genes that may exhibit association either directly or functionally related to PPP3CB:

- **PPP3CB**: The primary coding gene that the lncRNA is associated with.
- **CALM1, CALM2, CALM3**: These genes encode calmodulin proteins involved in calcium signaling.
- **NFAT family members (e.g., NFATC1, NFATC2)**: These transcription factors are regulated by calcineurin and are involved in immune response and cardiac function.
  
This list is by no means exhaustive, and detailed expression profiling studies could reveal more genes that are co-regulated or functionally connected to PPP3CB-AS1.

### 2. Aging and Age-Related Diseases

While there may not be extensive literature specifically outlining PPP3CB-AS1's direct role in aging, lncRNAs like PPP3CB-AS1 often have implications in various age-related processes:

- **Cardiac Development and Hypertrophy**: Given that PPP3CB is involved in cardiac hypertrophy, which can worsen with aging, PPP3CB-AS1 might play a role in age-related cardiac diseases.
- **Neurodegenerative Diseases**: Alterations in calcium signaling pathways can have implications for neurodegeneration, and PPP3CB’s involvement in neuronal signaling may imply a role for PPP3CB-AS1 in processes related to aging and conditions like Alzheimer's disease.

### 3. Drug Interactions

Currently, specific drugs directly interacting with PPP3CB-AS1 have not been extensively documented. However, since PPP3CB-AS1 is associated with the PPP3CB gene, which itself is influenced by certain drugs that affect calcium signaling, you could consider:

- **Calcineurin Inhibitors**: Drugs like cyclosporine and tacrolimus affect calcineurin's function and might indirectly relate to the pathways that PPP3CB-AS1 is involved in.
  
More specific research and database exploration are needed to identify any precise drug interactions involving PPP3CB-AS1 directly.

### 4. Pathways and Biological Processes

PPP3CB-AS1 is likely involved in several biological processes due to its association with the PPP3CB:

- **Calcium signaling pathways**: Given the involvement of PPP3CB in calcineurin signaling and its role in T-cell activation and muscle hypertrophy.
- **T-cell activation**: The calcineurin pathway, which PPP3CB is part of, is crucial in mediating T-cell responses.
- **Cardiac functions**: PPP3CB is known to play a role in cardiac hypertrophy, suggesting PPP3CB-AS1 could be involved in cardiac health and disease.

Research on lncRNAs is continually evolving, and PPP3CB-AS1 may have additional roles or associations that are yet to be discovered.