### SNORA2C Gene Summary

**Gene Symbol**: SNORA2C

SNORA2C (Small Nucleolar RNA, C/D Box 2C) is a member of the small nucleolar RNA (snoRNA) family. It is involved in the modification of ribosomal RNA (rRNA), specifically in the methylation of the 2'-O-ribose moiety of target nucleotides, which is essential for the proper biogenesis and function of ribosomes.

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### 1. Associated Genes

While specific gene associations outside those typically mentioned in summaries may not be extensively documented, SNORA2C is often studied alongside other snoRNAs and ribosomal protein genes due to its functional role in rRNA modification. Some potential associated genes may include:

- **RPL (Ribosomal Protein L)** genes, which are part of the ribosomal complex that relies on snoRNA modifications for function.
- Other members of the **C/D box snoRNA** family, as they are often functionally related.

### 2. Aging and Age-Related Diseases

Research into the role of snoRNAs such as SNORA2C in aging is ongoing, but there are certain points to consider:

- **Cellular Aging**: Alterations in snoRNA expression, including SNORA2C, have been correlated with changes in ribosome biogenesis during aging, which may impact cellular protein synthesis and functionality.
- **Age-Related Diseases**: Some studies suggest that dysregulation of snoRNAs can be implicated in age-related diseases, including cancer and neurodegenerative disorders, where altered protein synthesis may play a role. However, specific associations between SNORA2C and particular age-related diseases require further research.

### 3. Drug Interactions

Currently, there are no specific drugs or drug classes directly known to interact with the SNORA2C gene. Drug interactions may relate indirectly to the gene through its involvement in ribosome function or associated pathways, although the direct pharmacological impact on SNORA2C itself might not be well-characterized.

### 4. Pathways and Biological Processes

SNORA2C is primarily involved in:

- **Ribosome Biogenesis**: It plays a crucial role in the assembly and maturation of ribosomal RNA, which is essential for protein synthesis.
- **Nucleolar Functions**: As a snoRNA, it is localized within the nucleolus and is integral to the post-transcriptional modification of rRNAs.
- **Methylation Processes**: SNORA2C specifically is involved in 2'-O-methylation of rRNA, which is necessary for the structural and functional integrity of the ribosome.

Overall, SNORA2C is a vital component of the cellular machinery that ensures the proper function of ribosomes and, by extension, affects a wide variety of biological processes due to its direct role in protein synthesis. Further studies on its involvement in aging and disease contexts may provide deeper insights into its functional implications in health and disease.