### RNU7-105P Gene Overview

**Gene Symbol:** RNU7-105P

The RNU7-105P gene is a member of a class of small nucleolar RNAs (snoRNAs). These snoRNAs are primarily involved in the modification and processing of ribosomal RNA (rRNA) within the nucleolus, playing critical roles in the biogenesis of ribosomes.

### 1. Associated Genes

While specific interactions or associations with other genes may not be extensively documented for RNU7-105P, snoRNAs like RNU7-105P often function in networks with other snoRNAs and proteins that are involved in ribosome biogenesis. Some genes that could be indirectly associated are:

- **RNU7-1:** A closely related snoRNA involved in the methylation of rRNA.
- **NOP58, NOP56, NOP14:** Proteins that are part of the NOP complex, which is involved in the biogenesis of snoRNPs that include snoRNAs like RNU7-105P.

### 2. Aging and Age-Related Diseases

Research has shown that changes in snoRNA expression can be associated with aging and age-related diseases. Although direct associations specifically for RNU7-105P may not be well-documented, alterations in the expression of snoRNAs, in general, have been implicated in:

- **Neurodegenerative diseases:** Changes in snoRNA profiles have been observed in Alzheimer's disease and other forms of dementia.
- **Cancer:** Aberrant expression of snoRNAs has been associated with various cancers, influencing the regulation of gene expression and cellular proliferation.

### 3. Drug Interactions

Currently, there are no specific drugs or drug classes known to directly interact with the RNU7-105P gene. However, since snoRNAs often regulate rRNA processing and ribosome function, it is plausible that general drugs affecting ribosomal function (like some antibiotics) might indirectly influence the context where snoRNAs are relevant. Further experimental data would be needed for precise drug associations.

### 4. Pathways and Biological Processes

RNU7-105P is primarily involved in the following biological processes and pathways:

- **Ribosome biogenesis:** The primary function of snoRNAs, including RNU7-105P, is to guide the modification of rRNAs, which is crucial for the assembly of ribosomes.
- **RNA modification:** RNU7-105P is involved in the chemical modification of rRNA (e.g., methylation), which is essential for the stability and function of ribosomes.
- **Nucleolar organization:** Being a snoRNA, it plays a role in maintaining nucleolar structure and function.

Understanding the role of snoRNAs like RNU7-105P in these pathways contributes to our knowledge of cellular function, growth, and the aging process. More research is necessary to establish the precise physiological roles and clinical implications of RNU7-105P in health and disease.