### SNORD114-16 Gene Overview

**Gene Symbol:** SNORD114-16  
**Type:** Small nucleolar RNA (snoRNA) gene  
**Location:** Located in the nucleolus, SNORD114-16 is part of the SNORD114 family, which includes several other snoRNAs known for their roles in the biogenesis of ribosomal RNA (rRNA) and modification of pre-rRNA.

### 1. Associated Genes
While the exact relationships to other genes may not be explicitly detailed in the NCBI or UniProt summaries, SNORD114-16 is part of a larger family of snoRNAs, which often work in conjunction with other snoRNA genes, such as:
- SNORD114-12
- SNORD114-13
- SNORD114-7
Additionally, the snoRNAs may also be linked indirectly to genes involved in ribosome biogenesis, including RPS (ribosomal protein genes) and RNA polymerases that synthesize rRNA.

### 2. Aging and Age-Related Diseases
Research into the involvement of small nucleolar RNAs in aging is still emerging, and while specific aging-related functions of SNORD114-16 may not be well-defined, the general functions of snoRNAs in ribosomal RNA modification and processing could implicate them in the broader context of cellular aging and developmental processes. Alterations in rRNA modifications and ribosome activity may contribute to age-related decline in cellular function, which can impact various diseases associated with aging, such as neurodegenerative diseases. However, specific studies directly linking SNORD114-16 to aging or particular age-related diseases have not been prominently highlighted in current literature.

### 3. Drug Interactions
As of my last update in October 2023, there are no specific drugs or drug classes that are directly known to interact with SNORD114-16. However, general classes of drugs that modulate nucleolar functions or RNA metabolism may indirectly influence the activity of small nucleolar RNAs, including SNORD114-16. 

### 4. Pathways and Biological Processes
SNORD114-16 is primarily involved in the following biological processes:
- **Ribosome Biogenesis:** Facilitation of the maturation and modification of rRNA molecules, which are essential components of the ribosome.
- **Precursor rRNA Processing:** Participation in the post-transcriptional modification of pre-rRNA, including methylation.
- **Gene Regulation:** Involvement in the regulation of gene expression through modification of rRNA.

Moreover, the activity of snoRNAs like SNORD114-16 has been linked to broader regulatory networks that influence cell proliferation and differentiation.

### Conclusion
In summary, SNORD114-16 is a small nucleolar RNA with crucial roles in ribosome biogenesis and pre-rRNA modification, although specific information about its interactions with aging, drug interactions, and specific associated genes may be less defined in the current scientific literature. Continued research may elucidate further details on its biological significance and pathology involvement.