### ZNF195 Gene Overview

**Gene Symbol:** ZNF195  
**Location:** Chromosome 11p15.5  
**Function:** Encodes a protein that is part of the Krueppel C2H2-type zinc-finger protein family, functioning primarily as a transcription factor involved in various cellular processes.

#### 1. Associated Genes
ZNF195 has been explored in relation to several other genes, particularly those involved in the context of cancer and genetic regulation. While the NCBI and UniProt summaries don’t specify additional genes, studies suggest associations with the following:

- **KCNQ1**
- **KCNQ1OT1**
- **H19**
- **IGF2**  
These associations are primarily based on its proximity to imprinted genes and involvement in genomic imprinting and regulation, particularly in contexts that might relate to tumors such as Wilms' tumor.

#### 2. Aging and Age-Related Diseases
Currently, the specific role of ZNF195 in aging or age-related diseases is less well-defined. However, due to its function as a transcription factor, it has potential links to gene expression changes associated with aging and may play a role in cancer biology, particularly in Wilms' tumors. 

- **Cancer:** The proximity to imprinted domains involved in Wilms' tumors suggests a potential link between expression alterations of ZNF195 and tumorigenesis, which increases with age.
- **Epigenetics:** Imprinting and regulatory functions of zinc-finger proteins are known to be involved in age-related epigenetic changes.

#### 3. Drug Interactions
As of the latest information, there are no specific drugs or drug classes directly associated with ZNF195. However, because ZNF195 may play a role in transcriptional regulation and potentially in cancer biology, it could potentially interact indirectly with anti-cancer therapeutics or drugs affecting gene expression through epigenetic modulation. Future studies may elucidate specific pharmacological interactions as research progresses.

#### 4. Pathways and Biological Processes
Several key biological processes and pathways are associated with ZNF195:

- **Transcription Regulation:** As a transcription factor, ZNF195 is likely involved in regulating the transcription of various target genes.
- **Cell Growth and Differentiation:** The role in cellular processes suggests involvement in pathways that regulate cell cycle and differentiation.
- **Imprinting and Regulation of Gene Expression:** Due to its location near an imprinted domain, ZNF195 may participate in epigenetic regulation, influencing gene expression patterns critical in development and potentially in oncogenesis.
- **Response to Stress and Apoptosis:** Zinc-finger proteins often respond to cellular stress and can be involved in apoptosis pathways.

### Summary
The ZNF195 gene is an important element in transcriptional regulation, particularly influenced by its chromosomal location. While associations with specific drugs are not well-defined, its potential implications in cancer and development warrant further investigation into its connections with aging and disease pathways, with a specific focus on its role in gene expression regulation near imprinted regions.