The MIR8081 gene is part of a broader group of microRNA (miRNA) genes that play crucial roles in the regulation of gene expression in multicellular organisms. Here are some additional details regarding MIR8081 based on your requests:

### 1. Associated Genes
While specific associations can vary across studies and contexts, some of the known target genes of MIR8081—and those that may exhibit regulation by this miRNA—include genes related to pathways such as those involved in cell proliferation, apoptosis, and differentiation. Examples of common target genes for many studied miRNAs include:
- **E2F transcription factors:** Important in cell cycle regulation.
- **BCL2 family members:** Related to apoptosis regulation.

However, specific target genes for MIR8081 may not be directly cataloged on standard databases, and research may need to be consulted for the most updated target listing.

### 2. Aging and Age-Related Diseases
While specific studies directly linking MIR8081 to aging or age-related diseases are limited, many miRNAs have been found to have roles in the regulation of cellular aging and senescence. MicroRNAs can influence cellular stress responses, apoptosis, and inflammation, all of which are important for understanding age-related disorders. Some potential implications of microRNA involvement in aging are:
- Regulation of genes associated with cellular senescence.
- Influence on mitochondrial function and oxidative stress, central factors in aging processes.
- Impact on neurodegenerative diseases, where microRNAs might regulate neuroinflammation or neuronal survival.

### 3. Drug and Drug Classes Interaction
As of my last training cutoff in October 2023, there is limited information on specific drugs explicitly interacting with MIR8081. However, it is known that many therapeutic agents in oncology and cardiology can be influenced by miRNA activity as they may target gene expressions modulated by miRNAs. It's well established that some classes of drugs can indirectly modulate miRNA expression or target the signaling pathways affected by them:
- **Chemotherapeutics:** Many cancer treatments can influence miRNA profiles.
- **Antioxidants:** Compounds aimed at reducing oxidative stress might influence miRNA expression linked to aging or stress response.

Further study into drugs that specifically correlate with MIR8081 would require literature review or database queries for targeted binding or regulation experiments.

### 4. Pathways and Biological Processes
MIR8081 is involved in various biological pathways and processes that include:
- **Gene silencing:** Direct involvement in the RNA-induced silencing complex.
- **Cellular proliferation and apoptosis:** Through the regulation of target genes that further the processes related to cell cycle and programmed cell death.
- **Response to cellular stress:** Participation in the regulatory networks responding to stress and injury, which is particularly relevant to disease contexts.
- **Developmental processes:** Mirroring the role of miRNAs in differentiation and development stages.
  
Specific pathways may include those cataloged in databases like KEGG or Reactome, where miRNAs generally have roles in signaling cascades, development, and metabolic processes.

### Conclusion
MIR8081, like other microRNAs, is a versatile regulator of gene expression with implications across various biological processes, including developmental biology, disease mechanisms, and potentially aging. While more detailed studies that directly explore its functional roles are necessary, it continues to be a significant area of interest in molecular biology and therapeutic development. For the most current and thorough interactions or associations, continued research and exploration in scientific literature or updated genomic databases are advised.