### Summary of GAS6-DT Gene

**Gene Symbol:** GAS6-DT  
**Full Name:** GAS6 Divergent Transcript  
**Chromosomal Location:** GAS6-DT is located on human chromosome 17.

GAS6-DT is a long non-coding RNA (lncRNA) that is believed to be involved in various cellular processes, including gene regulation, cellular differentiation, and responses to stress. As a divergent transcript of the GAS6 gene, it is suggested to play a role in the regulation of GAS6 expression and may have implications in different biological pathways and processes.

### 1. Associated Genes
While GAS6-DT is directly associated with the GAS6 gene, known for its role in coagulation, cell survival, and signaling pathways related to apoptosis and inflammation, there are several other genes related to the GAS6 signaling pathway and potential regulatory networks. Some of these include:

- **AXL** - A receptor tyrosine kinase, which is activated by GAS6.
- **TYRO3** - Another receptor involved in the GAS6 signaling pathway.
- **MER** - A third receptor in the TAM receptor family closely associated with GAS6 signaling.

### 2. Aging or Age-related Disease Associations
- **GAS6 and Aging:** Although specific studies on GAS6-DT in the context of aging are limited, GAS6 itself has been implicated in various age-related conditions, such as cardiovascular diseases and neurodegenerative disorders. GAS6 has anti-apoptotic and tissue-repair functions, which may contribute to its role in aging. Elevated levels of GAS6 expression have been associated with chronic inflammation often seen in aging and age-related diseases.
- **Potential Relevance:** Due to its regulatory relationship with GAS6, GAS6-DT may play an indirect role in modulating these pathways, contributing to age-related cellular dysfunction.

### 3. Known Drug Interactions
Currently, there are no specific drugs or drug classes that are documented to directly interact with GAS6-DT. However, GAS6 and its signaling receptors (AXL, TYRO3, MER) have been explored for therapeutic targeting in various contexts—particularly in cancer and inflammatory diseases. Drugs that target these pathways might indirectly affect GAS6-DT expression and function.

### 4. Pathways and Biological Processes
GAS6-DT is involved in several important biological pathways and processes:

- **GAS6 Pathway:** As a divergent transcript, GAS6-DT may be involved in the regulation of signaling pathways activated by GAS6, including the TAM receptor tyrosine kinase signaling pathway, which is important for modulating inflammation and apoptosis.
- **Cellular Differentiation:** GAS6 and its associated pathways play a role in macrophage differentiation and function, potentially implicating GAS6-DT in these processes.
- **Anti-inflammatory Responses:** The GAS6 pathway has been linked to the resolution of inflammation, and GAS6-DT may play a regulatory role in promoting or modulating these effects.
  
Overall, further research is needed to fully elucidate the functional roles and relevance of the GAS6-DT gene in various biological processes, particularly in the context of aging and disease.