### FLRT3 Gene Overview

**Gene Symbol:** FLRT3  
**Chromosomal Location:** Located on chromosome 3.  

**General Functions:** 
The FLRT3 gene encodes a member of the fibronectin leucine-rich transmembrane protein (FLRT) family, which is involved in key biological processes including cell adhesion, migration, and axon guidance. The protein acts as a signaling molecule, influencing the interactions between cells and their extracellular environment.

### Additional Associated Genes
While the following genes are not explicitly mentioned in the summaries, studies have shown associations with FLRT3:
1. **ADGRL3 (Latrophilin 3)** - Involved in cell-cell adhesion.
2. **ROBO1** - Plays a role in axon guidance and interaction with FLRT3.
3. **UNC5B** - A member of the UNC-5 family implicated in neuron guidance.
4. **NTN1 (Netrin 1)** - Engages with FLRT3 for mediating axon attraction.

### Aging and Age-Related Diseases
Currently, the literature does not provide extensive direct links between FLRT3 and aging or common age-related diseases. However, its roles in cell adhesion, neuronal guidance, and vascular development suggest a potential impact on neurodegenerative diseases and vascular pathologies, which often exhibit age-related characteristics. Research may explore these- but as of the latest data, no concrete associations have been established specifically.

### Drug Interactions
As of the data available up to October 2023, there are no specific drugs or drug classes that have been conclusively linked to FLRT3 activity or modulation. However, due to its involvement in various signaling pathways and cellular processes, investigations into therapies targeting its pathways could yield insights in the future.

### Pathways and Biological Processes
The FLRT3 gene is an active participant in several critical biological processes:
1. **Cell Adhesion**: Promotes interactions between cells through adhesion molecules.
2. **Axon Guidance**: Influences neuronal development and pathways for growing axons, often acting in coordination with other signaling molecules.
3. **Neurite Outgrowth**: Enhances the growth of neurites in vitro, contributing to the formation of neural networks.
4. **Vascular Development**: Particularly in retinal development, showcasing a role in the formation and remodeling of blood vessels.
5. **Morphogenesis**: Essential for normal tissue and organ development during embryogenesis, e.g., ventral closure and endoderm migration.

### Summary
FLRT3 serves as a key player in multiple pathways that influence cell adhesion and neuronal connectivity. Its functions extend to significant roles in embryonic development and potential implications in neurobiology and vascular development. Further research may elucidate its specific relevance in age-related processes or offer insight into therapeutic approaches targeting its pathways.