### CEACAM19 Gene Overview

**Gene Symbol:** CEACAM19  
**Chromosomal Location:** The CEACAM19 gene is located on chromosome 19 in humans.  
**Entrez Gene ID:** 10349 (for reference)  
**Function:** The CEACAM19 gene encodes a member of the carcinoembryonic antigen-related cell adhesion molecule (CEACAM) family. This gene is believed to have roles in cell adhesion and signal transduction and may be involved in the immune response and tumor progression.

### Expression Profile
As highlighted, CEACAM19 is ubiquitously expressed, with particularly high levels in:
- Prostate
- Uterus
- Fetal brain
- Mammary gland
- Adrenal gland
- Skeletal muscle
- Small intestine
- Kidney

Lower expression levels are noted in:
- Lung
- Cerebellum
- Testis
- Liver
- Pancreas
- Bone marrow
- Ovary

### 1. Associated Genes
CEACAM19 shares homology with several other CEACAM family members, including:
- **CEACAM1**: Involved in immune response and cell signaling.
- **CEACAM5 (CEA)**: Associated with cancer, especially colorectal and breast cancer.
- **CEACAM6**: Also implicated in cancer development and progression.

### 2. Aging & Age-Related Diseases
Research suggests that CEACAM family members may play roles in age-related processes and diseases. CEACAM19 is still under investigation; however, CEACAM1 and other family members have been linked to:
- Oncology: CEACAM proteins, including CEACAM19, have been noted in cancer pathways and tumor microenvironments, indicating potential links to increased cancer susceptibility with aging.
- Immune Response: Changes in cell adhesion molecules are observed in aging, with potential impacts on immune system efficacy.

### 3. Drug Interactions
Currently, there are limited reports specifically linking drugs that interact with CEACAM19. Given its expression in various tissues and potential roles in cancer:
- **Cancer Therapeutics**: Drugs targeting pathways associated with CEACAM proteins (like monoclonal antibodies against CEACAM5) may indirectly impact CEACAM19, but no direct drug interactions are well-documented in public databases.

### 4. Pathways & Biological Processes
CEACAM19 may be involved in several biological pathways and processes:
- **Cell Adhesion**: Plays a potential role in cell-cell interactions.
- **Immune Regulation**: Likely involved in immune cell signaling pathways.
- **Tissue Development**: Impacts development and differentiation in various tissues, particularly in cancer and during embryonic development.

Research into CEACAM19 and its functional implications is ongoing, and additional discoveries may further elucidate its role in health and disease. As the understanding of this gene deepens, its connections with aging, cancer biology, and therapeutic interventions will become clearer.