### Overview of the CPSF2 Gene

**Gene Symbol:** CPSF2  
**Gene Function:** The CPSF2 gene encodes a protein that is a critical component of the cleavage and polyadenylation specificity factor (CPSF) complex. This complex plays a vital role in the process of pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence for polyadenylation. CPSF2 is involved in mRNA cleavage and the addition of a poly(A) tail, which are crucial for mRNA stability, export from the nucleus, and translation.

### 1. Associated Genes
CPSF2 interacts with several other genes and proteins, particularly those involved in RNA processing and regulation. Some of the notable associated genes include:
- **CPSF1**: Another component of the CPSF complex.
- **CPSF3**: Involved in the cleavage and polyadenylation process.
- **CPSF4**: Interacts within the CPSF complex.
- **Poly(A) polymerase genes**: Such as **PAPOLA**, involved in polyadenylation.

### 2. Aging and Age-Related Diseases
While direct associations between CPSF2 and specific age-related diseases are not extensively documented, its role in mRNA processing is inherently linked to gene expression regulation, which can impact aging. Dysregulation in mRNA polyadenylation has been implicated in various age-related conditions, including neurodegenerative diseases and cancers. Alterations in mRNA metabolism and stability, often linked to CPSF complex functionality, could potentially contribute to the aging process.

### 3. Drug Interactions
Currently, there is limited specific information on drugs directly interacting with the CPSF2 gene; however, drugs that generally affect RNA metabolism or that target RNA polymerases may have downstream effects on the pathways involving CPSF2. Chemotherapeutic agents that influence cellular RNA processes could indirectly affect the function of CPSF2.

### 4. Biological Pathways and Processes
CPSF2 is involved in several key biological pathways and processes, including:
- **mRNA processing**: As part of the CPSF complex, CPSF2 is directly involved in polyadenylation and cleavage of pre-mRNA.
- **Gene expression**: By influencing the stability and translation of mRNA, CPSF2 plays a role in overall gene expression regulation.
- **Nuclear mRNA metabolic processes**: This includes mRNA splicing, capping, and nuclear export.

### Conclusion
The CPSF2 gene plays a crucial role in the regulation of mRNA metabolism, which is essential for proper gene expression. Its involvement in the CPSF complex links it to processes critical for cellular functions and integrity, thereby impacting various physiological conditions, including aging and possibly age-related diseases. Further research is needed to elucidate specific drug interactions and detailed mechanistic roles related to aging.