### RPSAP61 Gene Overview

**Gene Symbol:** RPSAP61  
**Function:** RPSAP61 (Ribosomal Protein S5 Acute Phase 61) is a non-coding RNA gene that plays a role in the regulation of gene expression and possibly in splicing and ribosome biogenesis. It is located on chromosome 1 and is associated with various biological processes.

### 1. Associated Genes
RPSAP61 has been shown to have potential interactions or associations with several genes, although precise details may depend on specific research contexts:

- **RPS5 (Ribosomal Protein S5):** As part of the ribosomal protein family, it is involved in the assembly of ribosomes and protein synthesis.
- **RPSA (Ribosomal Protein SA):** A component of the ribosome and may interact functionally with RPSAP61.
- **Other neighboring genes on chromosome 1** may also exhibit regulatory or expression correlation, but specific instances can vary by study.

### 2. Aging and Age-Related Diseases
While there may not be extensive direct evidence linking RPSAP61 specifically to aging, non-coding RNAs have known roles in cellular processes that contribute to aging and age-related diseases such as:

- **Cellular Senescence:** Non-coding RNAs like RPSAP61 may influence pathways that involve cellular senescence, a key feature of aging.
- **Inflammation:** Some studies suggest a role in inflammatory responses, which are connected to numerous age-related diseases, including cardiovascular diseases and neurodegeneration.

### 3. Drug Interactions and Drug Classes
As of my last update, no specific drugs or drug classes are directly known to interact with RPSAP61. However, further research may uncover associations with drugs that target non-coding RNAs, particularly those involved in gene regulatory networks. Drugs that impact ribosomal function, such as certain antibiotics, could perturb pathways related to RPSAP61 indirectly.

### 4. Pathways and Biological Processes
RPSAP61 is involved in several critical biological processes:

- **Ribosome Biogenesis:** Participation in the assembly and maintenance of ribosomal structures.
- **Gene Expression Regulation:** Modulation of transcription or post-transcriptional processes, potentially influencing mRNA splicing.
- **Response to Stress:** May be implicated in mechanisms that help cells cope with stress conditions.
- **Cell Cycle Regulation:** Non-coding RNAs can play roles in the control of the cell cycle, though specific details for RPSAP61 may require further elucidation.

This gene is an example of how non-coding RNA is beginning to be understood as crucial players in the complex interplay of gene regulation and expression, especially in the context of cellular aging and integrity. Further research is warranted to deepen the understanding of RPSAP61's functions and implications in health and disease.