The GAPDHP71 gene, which stands for "Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 71 kDa," is a gene encoding a protein involved in the glycolytic pathway. The protein it encodes is a member of the glyceraldehyde-3-phosphate dehydrogenase (GAPDH) family, which plays essential roles in carbohydrate metabolism.

### 1. Associated Genes
While specific additional genes directly associated with GAPDHP71 may not be widely documented, similar genes in the GAPDH family include:

- **GAPDH** (Glyceraldehyde-3-phosphate dehydrogenase): The most studied member of this family and a key enzyme in glycolysis.
- **GAPDHS** (Glyceraldehyde-3-phosphate dehydrogenase, spermatogenic): plays a role in spermatogenesis.
- **GAPDHP**: Another member of the glyceraldehyde-3-phosphate dehydrogenases involved in energy metabolism.

### 2. Aging and Age-Related Diseases
Research on GAPDHP71 and its association with aging or age-related diseases is limited. However, GAPDH proteins, in general, have been implicated in:

- **Cellular senescence**: Some studies suggest that GAPDH may play roles in oxidative stress response, which is relevant to the aging process.
- **Neurodegenerative disorders**: Alterations in GAPDH function have been linked to Alzheimer's and other neurodegenerative diseases.
- **Metabolic syndromes**: Given its role in energy metabolism, dysregulation of GAPDH proteins may contribute to conditions such as diabetes, which is often associated with aging.

### 3. Drug Interactions
Specific drugs or drug classes that interact with GAPDHP71 may not be well established in the literature. However, GAPDH, as a target, has been implicated in some studies about:

- **Antioxidants**: Some antioxidants may influence GAPDH activity, potentially mitigating effects of oxidative stress in aging.
- **Metformin**: Known for its role in metabolic regulation and some studies suggest it may influence glycolytic enzymes including members of the GAPDH family.

### 4. Pathways and Biological Processes
GAPDHP71 is predominantly involved in the following pathways and biological processes:

- **Glycolysis**: The primary function is to catalyze the interconversion of glyceraldehyde-3-phosphate and 1,3-bisphosphoglycerate.
- **Metabolic pathways**: It plays a role in the broader metabolic pathways related to carbohydrate metabolism and energy production.
- **Glycerolipid metabolism**: Involved in the conversion of glycerol-3-phosphate to glyceraldehyde-3-phosphate, linking lipid metabolism with glycolytic pathways.
- **Cellular defense mechanisms**: Potential involvement in stress-response pathways, particularly against oxidative stress.

### Summary
GAPDHP71 is a glyceraldehyde-3-phosphate dehydrogenase involved in crucial metabolic pathways. Research about its implications in aging and associated diseases is emerging, particularly regarding metabolic disorders and neurodegeneration. It's useful in biochemical pathways, and although specific drug interactions are not well-defined, metabolic drugs and antioxidants have shown relevance in research contexts pertaining to this gene.