### Overview of SNORD114-22 Gene

**Gene Symbol:** SNORD114-22  
**Type:** Small nucleolar RNA (snoRNA)  
**Function:** SNORD114-22 is part of a family of small nucleolar RNAs that primarily function in the modification of other RNAs, particularly rRNA (ribosomal RNA) and, in some cases, snRNA (small nuclear RNA). Small nucleolar RNAs are involved in the methylation of rRNA, which is crucial for the assembly and function of ribosomes in protein synthesis.

### 1. Associated Genes
While the primary function of SNORD114-22 is linked to ribosomal RNA modification, it is typically associated with other members of the SNORD114 family, such as:

- **SNORD114-1**
- **SNORD114-3**
- **SNORD114-4**
- **SNORD114-13**
  
These genes are located within a cluster on chromosome 14 and are similar in function, contributing to the overall role of snoRNAs in rRNA biogenesis and modification.

### 2. Aging and Age-Related Diseases
Currently, there is limited information directly linking SNORD114-22 to specific aging processes or age-related diseases in the literature. However, given the role of snoRNAs in ribosome biogenesis, any impairment or dysfunction in these processes can contribute to cellular aging and age-related pathologies, such as cancer and neurodegenerative diseases. Further research may elucidate direct connections between SNORD114-22 and these conditions.

### 3. Drug Interaction
As of the available data up to October 2023, there are no specific drugs or drug classes documented to interact directly with SNORD114-22. Its role as a small nucleolar RNA suggests it may be indirectly affected by drugs that modify RNA processes or influence ribosome functionality, but more detailed studies would be necessary to establish such connections.

### 4. Pathways and Biological Processes
SNORD114-22 is involved in several biological processes, including:

- **Ribosome Biogenesis:** The main function of this gene is to act as a snoRNA that facilitates the methylation of rRNA, essential for constructing ribosomes.
- **RNA Modification:** It plays a role in the modification of RNA molecules, specifically through methylation processes that help in maintaining RNA stability and function.
- **Cellular Proliferation:** By influencing ribosome activity, it can also indirectly impact cellular growth and proliferation, given the importance of protein synthesis in these processes.

Overall, while SNORD114-22 is not linked directly to extensive biological functions outside of ribosomal RNA modification, its implications in the regulation of gene expression and protein synthesis can have far-reaching impacts on cellular health and function, potentially influencing aging and related diseases through these roles.