### CCDC86 Gene Overview

**Gene Symbol:** CCDC86  
**Location:** Chromosome (specific location varies by organism)  
**Cellular Compartment:** Nucleus (specifically in the nucleolus and nucleoplasm)  
**Function:** The CCDC86 gene encodes a protein that enables RNA binding activity and is known to be citrullinated by the enzyme PADI4.

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#### 1. Associated Genes:
While specific direct associations may require detailed interaction studies or databases like STRING or BioGRID for comprehensive insights, some genes that are frequently mentioned in conjunction with CCDC86 include:
- **PADI4:** This gene encodes an enzyme that citrullinates proteins, implicating it in autoimmune diseases and inflammation. 
- **RBPs (RNA Binding Proteins):** As CCDC86 is noted for its RNA binding activity, other related RBPs may be indirectly associated through RNA metabolism processes.
- **Citrullinated Proteins:** While not specific genes, proteins that are known to be citrullinated may share pathways with CCDC86.

#### 2. Aging or Age-related Diseases:
While direct associations of CCDC86 with age or age-related diseases may not be extensively documented, some potential implications could include:
- **Autoimmune Disorders:** Given its interaction with PADI4, which is linked to rheumatoid arthritis and other autoimmune disorders, CCDC86 may be implicated in the aging process whereby autoimmune diseases often manifest.
- **Gene Expression Changes in Aging Cells:** The RNA-binding capability of CCDC86 suggests a role in regulating gene expression, which can be altered during aging, contributing to senescence and age-related functional decline.

#### 3. Drug Interactions:
As of the current knowledge up to October 2023, there are no specific drugs or drug classes that are extensively documented to interact directly with CCDC86. However, potential interactions with drugs targeting PADI4, which has implications in inflammatory disorders, could affect the function or pathology associated with CCDC86 due to their shared biological context.

#### 4. Pathways and Biological Processes:
CCDC86 is involved in several biological processes and pathways, including but not limited to:
- **RNA Metabolism:** Given its RNA binding activity, it may play a role in mRNA splicing, transport, and stability.
- **Citrullination Pathway:** Protein citrullination involving PADI4 may influence various biological processes, including immune response and inflammation.
- **Cell Cycle Regulation:** Implicating knockdown or mutation effects on interaction with other proteins involved in cell cycle regulation might be observed.
- **Stress Responses and Cellular Signaling:** It might play a role in how cells respond to internal and external stressors, reflecting the relevance in age-related decline.

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In conclusion, CCDC86 is a gene of interest primarily due to its RNA binding ability and citrullination processes, potentially linking it to autoimmune diseases and broader implications in aging and cell biology. Further research is necessary to elucidate precise interactions, complete drug functionality, and profound associations with aging processes.