### DHX35 Gene Overview

**Gene Symbol:** DHX35  
**Entrez Gene Summary:** DHX35 is part of the DEAD box protein family characterized by the conserved DEAD motif (Asp-Glu-Ala-Asp). Members of this family are proposed RNA helicases and are implicated in various vital cellular processes, including RNA secondary structure remodeling, translation initiation, and ribonucleoprotein complex assembly. The exact function of the DHX35 gene product remains to be fully elucidated, although it is thought to participate in pre-mRNA splicing.

### Additional Associated Genes
While specific genes directly associated with DHX35 may not be consistently highlighted in PI or current databases, members of the DEAD box protein family often exhibit functional interactions. Some related genes and proteins include:

- **DDX6:** Known for its role in RNA metabolism and translation.
- **DHX9:** Involved in splicing and ribosome assembly processes.
- **DHX36:** Related to RNA unwinding and splicing regulation.

### Aging and Age-Related Diseases
As of the latest literature, there has been little direct study linking DHX35 to aging or age-related diseases. However, given the role of RNA helicases in fundamental cellular processes, dysfunction in this gene might theoretically contribute to age-related decline in cellular function or may be implicated in diseases characterized by aberrant RNA metabolism, such as neurodegenerative diseases. 

### Drugs or Drug Classes Interacting with DHX35
Currently, there are no specific drugs directly reported to interact with DHX35. However, given its potential involvement in RNA splicing, drugs that modify RNA splicing mechanisms or target RNA helicases may indirectly affect its function. This could include:

- **Spliceosome inhibitors:** Such as small molecule compounds designed to alter splicing patterns.
- **Antisense oligonucleotides:** Potentially affecting mRNA processing and stability.

### Pathways and Biological Processes
DHX35 is involved in several key biological pathways and processes, which include:

1. **RNA Splicing:** Participation in pre-mRNA splicing, contributing to the maturation of mRNA.
2. **Ribosome Biogenesis:** Involvement in the assembly of ribosomal components.
3. **Regulation of Translation:** By altering the secondary structure of RNA and facilitating the initiation process.

In addition to these processes, it may also play roles in:

- Cellular growth and division, given the implications of DEAD box proteins in these areas.
- Embryogenesis and spermatogenesis, which may be indirectly suggested by the characteristics of the DEAD box protein family.

### Conclusion
The DHX35 gene encodes a potential RNA helicase involved in critical RNA-related cellular processes, although comprehensive data on its specific interactions and roles in aging, drug interactions, or discrete biological pathways might still be limited. Further research into DHX35 may uncover new insights into its biological roles and relevance to health and disease.