### Gene Overview: SNORD114-7

**Gene Symbol:** SNORD114-7  
**Gene Type:** Small Nucleolar RNA (snoRNA)  
**Chromosomal Location:** Human chromosome 14 (14q32)  

SNORD114-7 is part of the small nucleolar RNA (snoRNA) family, which is primarily involved in the biogenesis of ribosomal RNA (rRNA) and modifications of other non-coding RNAs. Specifically, SNORD114-7 is classified as a C/D box snoRNA, which is involved in the methylation of rRNA and other target RNAs.

### Associated Genes

While specific associations beyond what is noted in NCBI or UniProt may not be well-documented for this particular snoRNA, it is worth noting that snoRNAs generally function alongside ribosomal proteins and other components of the ribonucleoprotein complexes involved in rRNA modification. Specific associations may include:

1. **Other SNORD Genes**: SNORD114-7 may be functionally related to other members of the SNORD114 family (e.g., SNORD114-1, SNORD114-2) due to their shared biological roles.
2. **Ribosomal Protein Genes**: These are genes encoding ribosomal proteins that also interact in processes involving rRNA modifications and synthesis.

### Aging and Age-Related Diseases

Research surrounding the specific role of SNORD114-7 in aging or age-related diseases is limited. However, given the association of snoRNAs with ribosome synthesis and function, it is plausible that disturbances in snoRNA function, including that of SNORD114-7, could potentially impact cellular aging and stress responses, given the critical role of protein synthesis in maintaining cellular function:

1. **General Impacts of snoRNAs on Aging**: Altered expression levels of snoRNAs have been associated with age-related decline in cellular function and various senescence-related mechanisms.
2. **Potential Links to Disease**: Changes in snoRNA expression can be implicated in certain cancers and genetic disorders, as these conditions can influence longevity through mechanisms like altered protein synthesis and cellular stress responses.

### Drug Interactions

Currently, there are no direct drug interactions or drug classes specifically known to target SNORD114-7. However, general treatments that influence cellular metabolism, ribosome biogenesis, or genetic regulation could indirectly affect the activity of snoRNAs. Notably:

1. **Cancer Therapeutics**: As snoRNAs are involved in ribosome biogenesis, drugs that target cancer-related pathways might influence the expression of snoRNAs, including SNORD114-7.

### Pathways and Biological Processes

SNORD114-7 is primarily involved in:

1. **Ribosome Biogenesis**: Plays a role in the chemical modifications of rRNA essential for ribosome assembly.
2. **rRNA Methylation**: Functions by guiding methylation modifications particularly to rRNA and possibly other non-coding RNAs.
3. **Gene Regulation**: SnoRNAs have been implicated in various regulatory processes, although the specific regulatory roles of SNORD114-7 require further elucidation.

### Summary

SNORD114-7, a small nucleolar RNA, plays a key role in ribosomal RNA modification and thus has important implications for ribosome biogenesis. Although direct links to aging, age-related diseases, and drug interactions are not extensively documented, its function as a snoRNA suggests that it could have significant indirect effects in these contexts. Further research is necessary to clarify its precise roles and associations within biological systems.