녹아웃 생쥐는 골격 근육 비대증을 반복적으로 나타냈고, 반면에 극적인 근육 위축은 미오스타틴이 체계적으로 투여될 때 관찰된다.
Knockout mice repeatedly manifested significant skeletal muscle hypertrophy, whereas dramatic muscle atrophy was observed when myostatin was being administered systemically.