TGR5 작용제를 투여했을 때 환자로부터 격리된 CD14 이상의 세포에서 발견되었는데, 이는 TGR5가 장내 염증 조절제임을 시사한다.
It was seen in CD14+ cells isolated from those patients when they were treated with TGR5 agonists, suggesting TGR5 is a regulator of inflammation in the bowel.