vitamin k reaction vitamin k reaction vitamin k reactions occur after injection with vitamin k, and there are two patterns of presentation, (1) a reaction may occur several days to 2 weeks after injection with skin lesions that are pruritic, red patches and plaques that can deep-seated, involving the dermis and subcutaneous tissue, or (2) with subcutaneous sclerosis with or without fasciitis, that appears at the site of injection many months after treatment.: 123 the latter pseudosclerodermatous reaction has been termed texier's disease and lasts several years.: 123 vitamin k reactionspecialtydermatology