azaprocin azaprocin azaprocin is a drug which is an opioid analgesic with approximately ten times the potency of morphine, and a fast onset and short duration of action. it was discovered in 1963, but has never been marketed. azaprocinclinical dataatc codenoneidentifiers iupac name 1-(3-((e)-3-phenylprop-2-enyl)-3,8-diazabicyclooctan-8-yl)propan-1-one cas number140844-23-1 ypubchem cid6433185chemspider16736583 yuniid20f1k1bypchemblchembl2105901 nchemical and physical dataformulac18h24n2omolar mass284.403 g·mol−13d model (jsmol)interactive imagemelting point170 to 175 °c (338 to 347 °f) smiles ccc(n12cc1cn(c2)c/c=c/c3=cc=cc=c3)=o inchi inchi=1s/c18h24n2o/c1-2-18(21)20-16-10-11-17(20)14-19(13-16)12-6-9-15-7-4-3-5-8-15/h3-9,16-17h,2,10-14h2,1h3/b9-6+/t16-,17+ ykey:rknspeobxhfntd-dqcujpbysa-n y ny (what is this?) (verify) the derivative substituted on the phenyl ring with a p-nitro group is more potent than the parent compound, around 25x the potency of morphine. the ring-opened 2,6-dimethylpiperazine analogues are also active, and a large family of opioid analgesic compounds derived from this parent structure have been developed over the last 40 years. one analogue, ap-237, has been used in china to treat the pain caused by cancer.