pabpc5 pabpc5 poly(a) binding protein cytoplasmic 5 is a protein that in humans is encoded by the pabpc5 gene. pabpc5identifiersaliasespabpc5, pabp5, poly(a) binding protein cytoplasmic 5external idsomim: 300407 mgi: 2136401 homologene: 5857 genecards: pabpc5 gene location (human)chr.x chromosome (human)bandxq21.31start91,434,595 bpend91,438,584 bpgene location (mouse)chr.x chromosome (mouse)bandx|x e1start118,836,893 bpend118,839,862 bprna expression patternbgeehumanmouse (ortholog)top expressed inachilles tendonleft adrenal glandsmooth muscle tissueislet of langerhanspopliteal arteryganglionic eminenceleft coronary arteryascending aortaright coronary arterygastric mucosatop expressed insuperior frontal gyruscerebellar cortexneural tubemirrormesencephalonhippocampus properolfactory bulbuterussupraoptic nucleusretinamore reference expression databiogpsn/aorthologsspecieshumanmouseentrez14088693728ensemblensg00000174740ensmusg00000034732uniprotq96du9q8c7d3refseq (mrna)nm_080832nm_053114refseq (protein)np_543022np_444344location (ucsc)chr x: 91.43 – 91.44 mbchr x: 118.84 – 118.84 mbpubmed searchwikidataview/edit humanview/edit mouse function this gene encodes a poly(a)-binding protein that binds to the polya tail found at the 3' end of most eukaryotic mrnas. it is thought to play a role in the regulation of mrna metabolic processes in the cytoplasm. this gene is located in a gene-poor region within the x-specific 13d-sy43 subinterval of the chromosome xq21.3/yp11.2 homology block. it is located close to translocation breakpoints associated with premature ovarian failure, and is therefore a potential candidate gene for this disorder. .