ideal vaccine is safe, effective after one or two injections, covers all serotypes, does not contribute to ade, is easily transported and stored, and is both affordable and cost-effective. anti-dengue day a poster in tampines, singapore, notifying people that there are ten or more cases of dengue in the neighbourhood (november 2015) international anti-dengue day is observed every year on 15 june. the idea was first agreed upon in 2010 with the first event held in jakarta, indonesia, in 2011. further events were held in 2012 in yangon, myanmar, and in 2013 in vietnam. goals are to increase public awareness about dengue, mobilize resources for its prevention and control and, to demonstrate the southeast asian region's commitment in tackling the disease. management there are no specific antiviral drugs for dengue; however, maintaining proper fluid balance is important. treatment depends on the symptoms. those who can drink, are passing urine, have no "warning signs" and are otherwise healthy can be managed at home with daily follow-up and oral rehydration therapy. those who have other health problems, have "warning signs", or cannot manage regular follow-up should be cared for in hospital. in those with severe dengue care should be provided in an area where there is access to an intensive care unit. intravenous hydration, if required, is typically only needed for one or two days. in children with shock due to dengue a rapid dose of 20 ml/kg is reasonable. the rate of fluid administration is then titrated to a urinary output of 0.5–1 ml/kg/h, stable vital signs and normalization of hematocrit. the smallest amount of fluid required to achieve this is recommended. invasive medical procedures such as nasogastric intubation, intramuscular injections and arterial punctures are avoided, in view of the bleeding risk. paracetamol (acetaminophen) is used for fever and discomfort while nsaids such as ibuprofen and aspirin are avoided as they might aggravate the risk of bleeding. blood transfusion is initiated early in people presenting with unstable vital signs in the face of a decreasing hematocrit, rather than waiting for the hemoglobin concentration to decrease to some predetermined "transfusion trigger" level. packed red blood cells or whole blood are recommended, while platelets and fresh frozen plasma are usually not. there is not enough evidence to determine if corticosteroids have a positive or negative effect in dengue fever. during the recovery phase intravenous fluids are discontinued to prevent a state of fluid overload. if fluid overload occurs and vital signs are stable, stopping further fluid may be all that is needed. if a person is outside of the critical phase, a loop diuretic such as furosemide may be used to eliminate excess fluid from the circulation. prognosis most people with dengue recover without any ongoing problems. the risk of death among those with severe dengue is 0.8% to 2.5%, and with adequate treatment this is less than 1%. however, those who develop significantly low blood pressure may have a fatality rate of up to 26%. the risk of death among children less than five years old is four times greater than among those over the age of 10. elderly people are also at higher risk of a poor outcome. epidemiology