amn082 amn082 amn082 (n,n′-dibenzhydrylethane-1,2-diamine) is a selective metabotropic glutamate receptor 7 (mglur7) allosteric agonist. it mimics the effect of glutamate. amn082 is the first selective mglur7 agonist and has expanded the potential array of research opportunities on the effects of mglur7 in the central nervous system. amn082 names iupac name n,n′-dibenzhydrylethane-1,2-diamine identifiers cas number 83027-13-8 y(dihydrochloride): 97075-46-2 y 3d model (jsmol) interactive image(dihydrochloride): interactive image chemspider 1459618 y(dihydrochloride): 9873115 y pubchem cid 11698390 inchi inchi=1s/c28h28n2/c1-5-13-23(14-6-1)27(24-15-7-2-8-16-24)29-21-22-30-28(25-17-9-3-10-18-25)26-19-11-4-12-20-26/h1-20,27-30h,21-22h2 ykey: dtzdsnqynpncpk-uhfffaoysa-n y(dihydrochloride): inchi=1s/c28h28n2.2clh/c1-5-13-23(14-6-1)27(24-15-7-2-8-16-24)29-21-22-30-28(25-17-9-3-10-18-25)26-19-11-4-12-20-26;;/h1-20,27-30h,21-22h2;2*1h ykey: yrqcdcnqansupb-uhfffaoysa-n y smiles c=1c=cc(=cc1)c(nccnc(c=2c=cc=cc2)c=3c=cc=cc3)c=4c=cc=cc4(dihydrochloride): cl.cl.n(ccnc(c1ccccc1)c2ccccc2)c(c3ccccc3)c4ccccc4 properties chemical formula c28h28n2 molar mass 392.546 g·mol−1 except where otherwise noted, data are given for materials in their standard state (at 25 °c , 100 kpa). n verify (what is yn ?) infobox references significance the two main types of glutamate receptors are ionotropic receptors and metabotropic receptors. ionotropic receptors (iglurs) are fast-acting ligand-gated ion channels and include ampa receptors, kainate receptors, and nmda receptors. metabotropic receptors are g-protein coupled receptors that mediate slower, longer-lasting effects through second messenger systems and are responsible for other neuronal functions that are not typically controlled by iglurs. mglurs are split into 3 separate groups (group i, group ii, group iii) based on pharmacological profile, sequence homology, and preferred signal transduction pathway. mglur7 is a member of group iii, the least studied of the groups. amn082 is pharmacological tool used to expand research on group iii mglurs.