etifelmine etifelmine etifelmine (inn; also known as gilutensin) is a stimulant drug. it was used for the treatment of hypotension (low blood pressure). etifelmineclinical dataatc codenoneidentifiers iupac name 2-(diphenylmethylidene)butan-1-amine cas number341-00-4pubchem cid68840chemspider62073 yunii1zfb1fr98echemblchembl2104621comptox dashboard (epa)dtxsid70187690 chemical and physical dataformulac17h19nmolar mass237.346 g·mol−13d model (jsmol)interactive image smiles c(=c(/c1ccccc1)c2ccccc2)(\cn)cc inchi inchi=1s/c17h19n/c1-2-14(13-18)17(15-9-5-3-6-10-15)16-11-7-4-8-12-16/h3-12h,2,13,18h2,1h3 ykey:wnkcjowtkxgere-uhfffaoysa-n y (verify) synthesis thieme patent: the base catalyzed reaction between benzophenone (1) and butyronitrile (2) gives 2-butanenitrile (3). catalytic hydrogenation reduces the nitrile group to a primary amine giving 1,1-diphenyl-2-ethyl-3-aminopropanol (4). the tertiary hydroxyl group is dehydrated by treatment with anhydrous hydrogen chloride gas, completing the synthesis of etifelmine (5).