lysophosphatidic acid receptor lysophosphatidic acid receptor the lysophosphatidic acid receptors (lpars) are a group of g protein-coupled receptors for lysophosphatidic acid (lpa) that include: lysophosphatidic acid receptor 1 (lpar1; formerly known as edg2, gpr26) lysophosphatidic acid receptor 2 (lpar2; formerly known as edg4) lysophosphatidic acid receptor 3 (lpar3; formerly known as edg7) lysophosphatidic acid receptor 4 (lpar4; formerly known as gpr23, p2ry9) lysophosphatidic acid receptor 5 (lpar5; formerly known as gpr92) lysophosphatidic acid receptor 6 (lpar6; formerly known as gpr87, p2ry5)