fechtner syndrome fechtner syndrome fechtner syndrome is a variant of alport syndrome characterized by leukocyte inclusions, macrothrombocytopenia, thrombocytopenia, nephritis, and sensorineural hearing loss. some patients may also develop cataracts. fechtner syndromeother namesalport syndrome with leukocyte inclusions and macrothrombocytopeniafechtner syndrome is inherited in an autosomal dominant manner.