cervical conization cervical conization cervical conization (cpt codes 57520 (cold knife) and 57522 (loop excision)) refers to an excision of a cone-shaped sample of tissue from the mucous membrane of the cervix. conization may be used for either diagnostic purposes as part of a biopsy or therapeutic purposes to remove pre-cancerous cells. cervical conizationicd-9-cm67.2 types include: cold knife conization (ckc): usually outpatient, occasionally inpatient loop electrical excision procedure (leep): usually outpatient. conization of the cervix is a common treatment for dysplasia following abnormal results from a pap smear. side effects cervical conization causes a risk for subsequent pregnancies ending up in preterm birth of approximately 30% on average, due to cervical incompetence.