alphamethadol alphamethadol alphamethadol (inn), or α-methadol, also known as alfametadol, is a synthetic opioid analgesic. it is an isomer of dimepheptanol (methadol), the other being betamethadol (β-methadol). alphamethadol is composed of two isomers itself, l-α-methadol, and d-α-methadol. the former compound, l-α-methadol, is an important active metabolite of levacetylmethadol (laam), an opioid substitute drug that is used clinically. both of alphamethadol's isomers bind to and activate the μ-opioid receptor and are active as opioid analgesics, similarly to those of alphacetylmethadol (α-acetylmethadol). not to be confused with alphacetylmethadol. alphamethadolclinical dataatc codenonelegal statuslegal status au: s9 (prohibited substance) ca: schedule i de: anlage i (authorized scientific use only) uk: class a us: schedule i identifiers iupac name (3r,6r)-6-(dimethylamino)-4,4-diphenyl-3-heptanol cas number17199-54-1pubchem cid62709chemspider56456uniixbd99qni42chemblchembl159660comptox dashboard (epa)dtxsid60872467 chemical and physical dataformulac21h29nomolar mass311.469 g·mol−13d model (jsmol)interactive image smiles o(c(c1ccccc1)(c2ccccc2)c(n(c)c)c)cc inchi inchi=1s/c21h29no/c1-5-20(23)21(16-17(2)22(3)4,18-12-8-6-9-13-18)19-14-10-7-11-15-19/h6-15,17,20,23h,5,16h2,1-4h3/t17-,20-/m1/s1key:qiraynifeoxspw-yljyhzdgsa-n legal status australia alphamethadol is considered a schedule 9 prohibited substance in australia under the poisons standard (february 2017). a schedule 9 substance is a substance which may be abused or misused, the manufacture, possession, sale or use of which should be prohibited by law except when required for medical or scientific research, or for analytical, teaching or training purposes with approval of commonwealth and/or state or territory health authorities.