penile pain penile pain penile pain refers to pain in the penis of human or otherwise. common causes penile injury circumcision penile fracture priapism phimosis peyronie's disease sexually transmitted infections chronic prostatitis/chronic pelvic pain syndrome cultural references priapus, a minor greek god of fertility, is marked by his oversized, permanent erection, which gave rise to the medical term priapism. some researchers believe the depiction of priapus' penis referred to a penile disease, and that paintings of priapus were used to ward off the disease.