poisoned as contaminated items warm up enough material to become an airborne toxic agent. an example of this was depicted in a british and canadian documentary about life in the trenches, particularly once the "sousterrain" (subways and berthing areas underground) were completed in belgium and france. towards the end of world war i, mustard agent was used in high concentrations as an area-denial weapon that forced troops to abandon heavily contaminated areas. us army world war ii gas identification poster, c. 1941–1945 since world war i, mustard gas has been used in several wars and other conflicts, usually against people who cannot retaliate in kind: united kingdom against the red army in 1919 alleged british use in mesopotamia in 1920 spain and france against the rifian resistance in morocco during the rif war of 1921–27 (see also: spanish use of chemical weapons in the rif war) italy in libya in 1930 the soviet union in xinjiang, republic of china, during the soviet invasion of xinjiang against the 36th division (national revolutionary army) in 1934, and also in the xinjiang war (1937) in 1936–37 italy against abyssinia (now ethiopia) in 1935-1936 the japanese empire against china in 1937–1945 the united states government tested effectiveness on us naval recruits in a laboratory setting at the great lakes naval base, june 3, 1945. the 2 december 1943 air raid on bari destroyed an allied stockpile of mustard gas on the ss john harvey. egypt against north yemen in 1963–1967 iraq against kurds in the town of halabja during the halabja chemical attack iraq against iranians in 1983–1988 possibly in sudan against insurgents in the civil war, in 1995 and 1997. in the iraq war, abandoned stockpiles of mustard gas shells were destroyed in the open air, and were used against coalition forces in roadside bombs. by isis forces against kurdish forces in iraq in august 2015. by isis against another rebel group in the town of mare' in 2015. according to syrian state media, by isis against syrian army during the battle in deir ez-zor in 2016. in 1943, during world war ii, a shipment of mustard gas from the us exploded aboard ss john harvey that was bombed during an air raid in the harbor of bari, italy. eighty-three of the 628 hospitalized victims who had been exposed to the mustard agent died. after wwii, stockpiled mustard gas was dumped by the british in the sea near port elizabeth, south africa, resulting in many cases of burns among trawler crews. the use of toxic gases or other chemicals, including mustard gas, during warfare is known as chemical warfare, and this kind of warfare was prohibited by the geneva protocol of 1925, and also by the later chemical weapons convention of 1993. the latter agreement also prohibits the development, production, stockpiling, and sale of such weapons. in september 2012, a us official stated that the rebel militant group isis was manufacturing and using mustard gas in syria and iraq, which was allegedly confirmed by the group's head of chemical weapons development, sleiman daoud al-afari, who has since been captured. development of the first chemotherapy drug as early as 1919 it was known that mustard agent was a suppressor of hematopoiesis. in addition, autopsies performed on 75 soldiers who had died of mustard agent during world war i were done by researchers from the university of pennsylvania who reported decreased counts of white blood cells. this led the american office of scientific research and development (osrd) to finance the biology and chemistry departments at yale university to conduct research on the use of chemical warfare during world war ii. as a part of this effort, the group investigated nitrogen mustard as a therapy for hodgkin's lymphoma and other types of lymphoma and leukemia, and this compound was tried out on its first human patient in december 1942. the results of this study were not published until 1946, when they were declassified. in a parallel track, after the air raid on bari in december 1943, the doctors of the u.s. army noted that white blood cell counts were reduced in their patients. some years after world war ii was over, the incident in bari and the work of the yale university group with nitrogen mustard converged, and this prompted a search for other similar chemical compounds. due to its use in previous studies, the nitrogen mustard called "hn2" became the first cancer chemotherapy drug, mustine (also called chlormethine), to be used. disposal in the united states, storage and incineration of mustard gas and other chemical weapons were carried out by the u.s. army chemical materials agency. disposal projects at the two remaining american chemical weapons sites were carried out near richmond, kentucky, and pueblo, colorado. although not yet declassified, toxicology specialists who dealt with the accidental puncturing of world war i gas stockpiles add that air force bases in colorado have been made available to assist veterans of the 2003 american war with iraq in which many marines were exposed to gas as caches of up to 25,000 lb (11,000 kg). the united nations definition of a weapon of mass destruction for mustard gas is 30,000 lb (14,000 kg), typically the marines and other coalition allies discovered caches of 25,000 pounds (11,000 kg) located across a road from 5,000 pounds (2,300 kg) caches as multiple memoirs attest. these were discovered by the assistance of host country allies, or through leaks affecting personnel in an area with a weapon and gas cache called an asp. new detection techniques are being developed in order to detect the presence of mustard gas and its metabolites. the technology is portable and detects small quantities of the hazardous waste and its oxidized products, which are notorious for harming unsuspecting civilians. the immunochromatographic assay would eliminate the need for expensive, time-consuming lab tests and enable easy-to-read tests to protect civilians from sulfur-mustard dumping sites. in 1946, 10,000 drums of mustard gas (2,800 tonnes) stored at the production facility of stormont chemicals in cornwall, ontario, canada, were loaded onto 187 boxcars for the 900 miles (1,400 km) journey to be buried at sea on board a 400 foot (120 m) long barge 40 miles (64 km) south of sable island, southeast of halifax, at a depth of 600 fathoms (1,100 m). the dump location is 42 degrees, 50 minutes north by 60 degrees, 12 minutes west. a large british stockpile of old mustard agent that had been made and stored since world war i at m. s. factory, valley near rhydymwyn in flintshire, wales, was destroyed in 1958. most of the mustard gas found in germany after world war ii was dumped into the baltic sea. between 1966 and 2002, fishermen have found about 700 chemical weapons in the region of bornholm, most of which contain mustard gas. one of the more frequently dumped weapons was "sprühbüchse 37" (sprübü37, spray can 37, 1937 being the year of its fielding with the german army). these weapons contain mustard gas mixed with a thickener, which gives it a tar-like viscosity. when the content of the sprübü37 comes in contact with water, only the mustard gas in the outer layers of the lumps of viscous mustard hydrolyzes, leaving behind amber-colored residues that still contain most of the active mustard gas. on mechanically breaking these lumps (e.g., with the drag board of a fishing net or by the human hand) the enclosed mustard gas is still as active as it had been at the time the weapon was dumped. these lumps, when washed ashore, can be mistaken for amber, which can lead to severe health problems. artillery shells containing mustard gas and other toxic ammunition from world war i (as well as conventional explosives) can still be found in france and belgium. these were formerly disposed of by explosion undersea, but since the current environmental regulations prohibit this, the french government is building an automated factory to dispose of the accumulation of chemical shells. in 1972, the u.s. congress banned the practice of disposing of chemical weapons into the ocean by the united states. 29,000 tons of nerve and mustard agents had already been dumped into the ocean off the united states by the u.s. army. according to a report created in 1998 by william brankowitz, a deputy project manager in the u.s. army chemical materials agency, the army created at least 26 chemical weapons dumping sites in the ocean offshore from at least 11 states on both the east coast and the west coast (in operation chase, operation geranium, etc.). in addition, due to poor recordkeeping, about one-half of the sites have only their rough locations known. in june 1997, india declared its stock of chemical weapons of 1,044 tonnes (1,151 short tons) of mustard gas. by the end of 2006, india had destroyed more than 75 percent of its chemical weapons/material stockpile and was granted extension for destroying the remaining stocks by april 2009 and was expected to achieve 100 percent destruction within that time frame. india informed the united nations in may 2009 that it had destroyed its stockpile of chemical weapons in compliance with the international chemical weapons convention. with this india has become the third country after south korea and albania to do so. this was cross-checked by inspectors of the united nations. producing or stockpiling mustard gas is prohibited by the chemical weapons convention. when the convention entered force in 1997, the parties declared worldwide stockpiles of 17,440 tonnes of mustard gas. as of december 2015, 86% of these stockpiles had been destroyed. a significant portion of the united states' mustard agent stockpile was stored at the edgewood area of aberdeen proving ground in maryland. approximately 1,621 tons of mustard agents were stored in one-ton containers on the base under heavy guard. a chemical neutralization plant was built on the proving ground and neutralized the last of this stockpile in february 2005. this stockpile had priority because of the potential for quick reduction of risk to the community. the nearest schools were fitted with overpressurization machinery to protect the students and faculty in the event of a catastrophic explosion and fire at the site. these projects, as well as planning, equipment, and training assistance, were provided to the surrounding community as a part of the chemical stockpile emergency preparedness program (csepp), a joint program of the army and the federal emergency management agency (fema). unexploded shells containing mustard gases and other chemical agents are still present in several test ranges in proximity to schools in the edgewood area, but the smaller amounts of poison gas (4 to 14 pounds (1.8 to 6.4 kg)) present considerably lower risks. these remnants are being detected and excavated systematically for disposal. the u.s. army chemical materials agency oversaw disposal of several other chemical weapons stockpiles located across the united states in compliance with international chemical weapons treaties. these include the complete incineration of the chemical weapons stockpiled in alabama, arkansas, indiana, and oregon. earlier, this agency had also completed destruction of the chemical weapons stockpile located on johnston atoll located south of hawaii in the pacific ocean. the largest mustard agent stockpile, at approximately 6,200 short tons, was stored at the deseret chemical depot in northern utah. the incineration of this stockpile began in 2006. in may 2011, the last of the mustard agents in the stockpile were incinerated at the deseret chemical depot, and the last artillery shells containing mustard gas were incinerated in january 2012. in 2008, many empty aerial bombs that contained mustard gas were found in an excavation at the marrangaroo army base just west of sydney, australia. in 2009, a mining survey near chinchilla, queensland, uncovered 144 105-millimeter howitzer shells, some containing "mustard h", that had been buried by the u.s. army during world war ii. in 2014, a collection of 200 bombs was found near the flemish villages of passendale and moorslede. the majority of the bombs were filled with mustard agents. the bombs were left over from the german army and were meant to be used in the battle of passchendale in world war i. it was the largest collection of chemical weapons ever found in belgium. a large amount of chemical weapons, including mustard gas, was found in a neighborhood of washington dc. the