rubulavirinae rubulavirinae rubulavirinae is a subfamily of viruses in the family paramyxoviridae. humans, apes, pigs, and dogs serve as natural hosts. there are currently 18 species in the two genera orthorubulavirus and pararubulavirus. diseases associated with this genus include mumps. members of the subfamily are collectively called rubulaviruses. the subfamily was previously a genus named rubulavirus but was elevated to subfamily in 2018. viruses of this subfamily appear to be most closely related to members of avulavirinae. rubulavirinae tem micrograph of a mumps orthorubulavirus particle virus classification (unranked): virus realm: riboviria kingdom: orthornavirae phylum: negarnaviricota class: monjiviricetes order: mononegavirales family: paramyxoviridae subfamily: rubulavirinae genera orthorubulavirus pararubulavirus taxonomy subfamily: rubulavirinae genus: orthorubulavirus genus: pararubulavirus structure rubulavirions are enveloped, with spherical geometries. the diameter is around 150 nm. rubulavirus genomes are linear, around 15kb in length. the genome codes for 8 proteins. genusstructuresymmetrycapsidgenomic arrangementgenomic segmentation rubulavirussphericalenvelopedlinearmonopartite life cycle viral replication is cytoplasmic. entry into the host cells is achieved after viral attachment to host cells. replication follows the negative stranded rna virus replication model. negative-stranded rna virus transcription, using polymerase stuttering, through co-transcriptional rna editing is the method of transcription. the virus exits the host cell by budding. humans, apes, pigs, and dogs serve as the natural host. transmission routes are respiratory and saliva. genushost detailstissue tropismentry detailsrelease detailsreplication siteassembly sitetransmission rubulavirushumans; apes; pigs; dogsnoneglycoproteinbuddingcytoplasmcytoplasmaerosols; saliva