delanterone delanterone delanterone (inn) (developmental code name gbr-21162), also known as 1α-methylandrosta-4,16-dien-3-one, is a steroidal antiandrogen described as an anti-acne agent which was never marketed. the compound showed poor efficacy as an antiandrogen in vivo in animals, suggestive of low activity or a short terminal half-life, and likely in relation to this was not further developed. it was described and characterized in the literature in 1977. delanteroneclinical dataother namesgbr-21162; 1α-methylandrosta-4,16-dien-3-oneidentifiers iupac name (1s,8s,9s,10r,13r,14s)-1,10,13-trimethyl-1,2,6,7,8,9,11,12,14,15-decahydrocyclopentaphenanthren-3-one cas number63014-96-0pubchem cid205969chemspider178468uniiam2kz47r0jchemblchembl2104221chemical and physical dataformulac20h28omolar mass284.443 g·mol−13d model (jsmol)interactive image smiles cc1cc(=o)c=c2c1(c3ccc4(c=ccc4c3cc2)c)c inchi inchi=1s/c20h28o/c1-13-11-15(21)12-14-6-7-16-17-5-4-9-19(17,2)10-8-18(16)20(13,14)3/h4,9,12-13,16-18h,5-8,10-11h2,1-3h3/t13-,16-,17-,18-,19-,20-/m0/s1key:gdonnnqfentlqc-vwtpsidosa-n