the development and/or progression of the neuron injury occurring in human diseases such as alzheimer's disease and parkinson's disease. human studies 15d-δ12,14-pgj2 and its pgd2 precursor have been demonstrated to suppress hair growth in studies of mouse and human follicular explant culture models; further studies examining the content of these two prostaglanidns in normal and balding tissue of mice and humans have implicated pgd2 and to a much lesser extent 15d-δ12,δ14-pgj2 in the development of male pattern baldness.