sib-1757 sib-1757 sib-1757 is a drug used in scientific research which was one of the first compounds developed that acts as a selective antagonist for the metabotropic glutamate receptor subtype mglur5. it has anti-hyperalgesia effects in animals. sib-1757 along with other mglur5 antagonists has been shown to have neuroprotective and hepatoprotective effects, and it is also used to study the role of the mglur5 receptor in brain development. sib-1757identifiers iupac name 6-methyl-2-(phenylazo)-3-pyridinol cas number31993-01-8 ypubchem cid6849066chemspider10654582comptox dashboard (epa)dtxsid00425754 echa infocard100.164.315 chemical and physical dataformulac12h11n3omolar mass213.240 g·mol−13d model (jsmol)interactive image smiles oc1ccc(c)nc1\n=n\c2ccccc2 inchi inchi=1s/c12h11n3o/c1-9-7-8-11(16)12(13-9)15-14-10-5-3-2-4-6-10/h2-8,16h,1h3/b15-14+key:locpvwireqignq-ccezhusrsa-n (verify)