multilocular cystic renal cell carcinoma multilocular cystic renal cell carcinoma multilocular cystic renal cell carcinoma (mcrcc) is rare subtype of renal cell carcinoma. histologically, the tumor has a fibrous capsule and contains multiple cysts with clear cells. multilocular cystic renal cell carcinomaspecialtyoncology/nephrology 1-5% of renal cell carcinomas are mcrcc.