16bo133 16bo133 16bo133 is a sars-like coronavirus (sl-cov) which was found in the greater horseshoe bat in south korea. it was published in 2019 and its genome was completely sequenced. the sequenced korean sarsr-cov strain belongs to the severe acute respiratory syndrome coronavirus 1, and its genome sequence similarity is 82.8%. 16bo133 virus classification (unranked): virus realm: riboviria kingdom: orthornavirae phylum: pisuviricota class: pisoniviricetes order: nidovirales family: coronaviridae genus: betacoronavirus subgenus: sarbecovirus species: sars-related coronavirus strain: 16bo133 discovery the 16bo133 virus was discovered in the oral cavity of the greater horseshoe bat in 2016. the genome of this virus strain is 29075 nt. among sarsr-covs, 16bo133 is the closest to the jtmc15 virus, which was published in 2016 and discovered in jilin, china, with a genome nucleic acid sequence similarity of 98.3%. compared with other sarsr-covs, these two viruses have the orf8 strain due to a frameshift mutation at the end of orf7b. the similarity of the genome nucleic acid sequence of 16bo133 virus and sars-cov is 82.8%. although other sarsr-cov strains have been found in korea in the past (b15-21 virus, etc.), none of them have been sequenced. the 16bo133 virus is the first korean sarsr-cov strain to be completely sequenced. phylogenetic a phylogenetic tree based on whole-genome sequences of sars-cov-1 and related coronaviruses is: sars‑cov‑1 related coronavirus 16bo133, 86.3% to sars-cov-1, rhinolophus ferrumequinum, north jeolla, south korea jtmc15, 86.4% to sars-cov-1, rhinolophus ferrumequinum, tonghua, jilin bat sars cov rf1, 87.8% to sars-cov-1, rhinolophus ferrumequinum, yichang, hubei btcov hku3, 87.9% to sars-cov-1, rhinolophus sinicus, hong kong and guangdong lyra11, 90.9% to sars-cov-1, rhinolophus affinis, baoshan, yunnan bat sars-cov/rp3, 92.6% to sars-cov-1, rhinolophus pearsoni, nanning, guangxi bat sl-cov ynlf_31c, 93.5% to sars-cov-1, rhinolophus ferrumequinum, lufeng, yunnan bat sl-cov ynlf_34c, 93.5% to sars-cov-1, rhinolophus ferrumequinum, lufeng, yunnan shc014-cov, 95.4% to sars-cov-1, rhinolophus sinicus, kunming, yunnan wiv1, 95.6% to sars-cov-1, rhinolophus sinicus, kunming, yunnan wiv16, 96.0% to sars-cov-1, rhinolophus sinicus kunming, yunnan civet sars-cov, 99.8% to sars-cov-1, paguma larvata, market in guangdong, china sars-cov-1 sars-cov-2, 79% to sars-cov-1