carotid groove carotid groove the carotid groove is an anatomical groove in the sphenoid bone located above the attachment of each great wing of the sphenoid bone. the groove is curved like the italic letter f, and lodges the internal carotid artery and the cavernous sinus. carotid groovesphenoid bone. upper surface. (carotid groove visible at left center.)base of the skull. upper surface. (sphenoid bone is in yellow, and carotid groove is labeled at center of sphenoid.detailslocationsphenoid boneidentifierslatinsulcus caroticus ossis sphenoidalista98a02.1.05.012ta2596fma54753anatomical terms of bone