amixetrine amixetrine amixetrine (inn) (brand name somagest; developmental code name cerm-898) is a drug that was formerly marketed in france but is now no longer sold. according to various sources it has been said to be an anti-inflammatory, antidepressant, antispasmodic, anticholinergic, antihistamine, and antiserotonergic, but its definitive indications and pharmacology are unclear. the drug was first synthesized in 1969 and was introduced in france in 1972. amixetrineclinical dataroutes ofadministrationoralatc codenonelegal statuslegal status in general: ℞ (prescription only) identifiers iupac name 1-pyrrolidine cas number24622-72-8 ypubchem cid71911chemspider64922 yunii7ul287ytpjchemblchembl2104080 nchemical and physical dataformulac17h27nomolar mass261.409 g·mol−13d model (jsmol)interactive image smiles o(ccc(c)c)c(c1ccccc1)cn2cccc2 inchi inchi=1s/c17h27no/c1-15(2)10-13-19-17(14-18-11-6-7-12-18)16-8-4-3-5-9-16/h3-5,8-9,15,17h,6-7,10-14h2,1-2h3 ykey:isrodtbnjuawej-uhfffaoysa-n y ny (what is this?) (verify) synthesis patent: reagent: the treatment of isoamyl alcohol (1) with styrene (2) at -10°c with dropwise addition of tert-butyl hypobromite gives (2-bromo-1-(isopentyloxy)ethyl)benzene (3). dispalcement of the halogen leaving group by pyrrolidine completes the synthesis of amixetrine (4).