cotadutide cotadutide cotadutide is an experimental drug for the treatment of type 2 diabetes mellitus. it lowers blood glucose levels by mimicking the human hormones glucagon-like peptide 1 and glucagon, which play a role in blood sugar regulation. the drug is a peptide that is injected under the skin. cotadutideclinical dataother namesmedi-0382routes ofadministrationsubcutaneous injectionatc codenonelegal statuslegal status investigational identifierscas number1686108-82-6pubchem cid134694273drugbankdb15194chemspider75531286uniiql6a9b13hwkeggd11304chemical and physical dataformulac167h252n42o55molar mass3728.092 g·mol−13d model (jsmol)interactive image smiles cccccccccccccccc(=o)n(ccc(=o)ncccc(c(=o)n(co)c(=o)n(ccc(=o)o)c(=o)n(cc1=cc=c(c=c1)o)c(=o)n(cc(c)c)c(=o)n(cc(=o)o)c(=o)n(co)c(=o)n(ccc(=o)o)c(=o)n(cccnc(=n)n)c(=o)n(c)c(=o)n(cccnc(=n)n)c(=o)n(cc(=o)o)c(=o)n(cc2=cc=cc=c2)c(=o)n(c(c)c)c(=o)n(c)c(=o)n(cc3=cnc4=cc=cc=c43)c(=o)n(cc(c)c)c(=o)n(ccc(=o)o)c(=o)n(c)c(=o)ncc(=o)ncc(=o)o)nc(=o)(cc(=o)o)nc(=o)(co)nc(=o)((c)o)nc(=o)(cc5=cc=cc=c5)nc(=o)((c)o)nc(=o)cnc(=o)(ccc(=o)n)nc(=o)(co)nc(=o)(cc6=cnc=n6)n)c(=o)o inchi inchi=1s/c167h252n42o55/c1-13-14-15-16-17-18-19-20-21-22-23-24-31-47-125(219)186-109(165(263)264)53-58-124(218)175-62-35-34-44-102(189-153(251)116(72-131(228)229)201-161(259)122(83-213)206-164(262)137(92(12)215)209-157(255)114(68-94-40-29-26-30-41-94)202-163(261)136(91(11)214)207-127(221)78-181-142(240)105(52-57-123(169)217)190-158(256)119(80-210)203-141(239)100(168)71-97-76-174-84-182-97)146(244)204-120(81-211)159(257)193-108(56-61-130(226)227)148(246)197-112(69-95-48-50-98(216)51-49-95)151(249)195-111(66-86(4)5)150(248)200-118(74-133(232)233)155(253)205-121(82-212)160(258)192-107(55-60-129(224)225)147(245)188-103(45-36-63-176-166(170)171)143(241)184-89(9)139(237)187-104(46-37-64-177-167(172)173)145(243)199-117(73-132(230)231)154(252)198-113(67-93-38-27-25-28-39-93)156(254)208-135(87(6)7)162(260)185-90(10)140(238)194-115(70-96-75-178-101-43-33-32-42-99(96)101)152(250)196-110(65-85(2)3)149(247)191-106(54-59-128(222)223)144(242)183-88(8)138(236)180-77-126(220)179-79-134(234)235/h25-30,32-33,38-43,48-51,75-76,84-92,100,102-122,135-137,178,210-216h,13-24,31,34-37,44-47,52-74,77-83,168h2,1-12h3,(h2,169,217)(h,174,182)(h,175,218)(h,179,220)(h,180,236)(h,181,240)(h,183,242)(h,184,241)(h,185,260)(h,186,219)(h,187,237)(h,188,245)(h,189,251)(h,190,256)(h,191,247)(h,192,258)(h,193,257)(h,194,238)(h,195,249)(h,196,250)(h,197,246)(h,198,252)(h,199,243)(h,200,248)(h,201,259)(h,202,261)(h,203,239)(h,204,244)(h,205,253)(h,206,262)(h,207,221)(h,208,254)(h,209,255)(h,222,223)(h,224,225)(h,226,227)(h,228,229)(h,230,231)(h,232,233)(h,234,235)(h,263,264)(h4,170,171,176)(h4,172,173,177)/t88-,89-,90-,91+,92+,100-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,135-,136-,137-/m0/s1key:yekuubpjrpxmbm-ptcfzacgsa-n cotadutide is in phase ii clinical trials as of february 2021.