nicotinyl alcohol nicotinyl alcohol nicotinyl alcohol (pyridylcarbinol) is a niacin derivative used as a hypolipidemic agent and as a vasodilator. it causes flushing and may decrease blood pressure. nicotinyl alcoholclinical dataother namesroniacol; roniacol tartrate; nicotinyl tartrate; nicotinyl alcohol tartrate; nicotinic alcohol; pyridylcarbinolahfs/drugs.commonographatc codec10ad05 (who) c04ac02 (who)identifiers iupac name (pyridin-3-yl)methanol cas number100-55-0 ypubchem cid7510chemspider7229 nunii9tf312056ychebichebi:45213comptox dashboard (epa)dtxsid6023367 echa infocard100.002.604 chemical and physical dataformulac6h7nomolar mass109.128 g·mol−13d model (jsmol)interactive image smiles occ1cccnc1 inchi inchi=1s/c6h7no/c8-5-6-2-1-3-7-4-6/h1-4,8h,5h2 n ny (what is this?) (verify) it appears as a crystal that dissolves in water and alcohol with ease, also soluble in ether; melting range 147–148 ºc. nicotinic acid is a brief peripheral vasodilator; this compound was made to make its action longer and effective. it provokes cutaneous flushing in head and upper thorax with heat, but with no major effects in blood pressure. it is used in peripheral vascular diseases, like arteriosclerosis obliterans, raynaud's disease, thromboangiitis obliterans (buerger's disease), arterial embolism, chilblains or migraine associated with vascular spasm. fischer and tebrock worked with this drug in more than two hundred patients for more than three years, achieving effective improvements, mainly in symptoms related to intermittent claudication, ulcer healing and others. derivatives at least a couple of uses for this agent were discovered over the years: eniclobrate mepiroxol nicofibrate pantenicate (topanicate, mg 28362)