dopamine agonist dopamine agonist a dopamine agonist (da) is a compound that activates dopamine receptors. there are two families of dopamine receptors, d2-like and d1-like, and they are all g protein-coupled receptors. d1- and d5-receptors belong to the d1-like family and the d2-like family includes d2, d3 and d4 receptors. dopamine agonists are primarily used in the treatment of parkinson's disease, and to a lesser extent, in hyperprolactinemia and restless legs syndrome. they are also used off-label in the treatment of clinical depression. the use of dopamine agonists is associated with impulse control disorders and dopamine agonist withdrawal syndrome (daws). dopamine agonistdrug classthe skeletal structure of dopamineclass identifiersuseparkinson's disease, hyperprolactinemia, restless legs syndromeatc coden04bcbiological targetdopamine receptors