list of adverse effects of axitinib list of adverse effects of axitinib this is a list of adverse effects of the anti-cancer drug axitinib, sorted by frequency of occurrence. very common very common (>10% incidence) adverse effects include: underactive thyroid decreased appetite headache dizziness taste changes haemorrhage high blood pressure cough shortness of breath speech disorder diarrhoea nausea vomiting abdominal pain stomatitis indigestion hand-foot syndrome dry skin rash joint aches and pains pain in the extremities proteinuria fatigue asthenia mucosal inflammation weight loss common common (1–10% incidence) adverse effects include: anaemia thrombocytopenia hyperthyroidism tsh-increased dehydration high blood potassium high blood calcium ringing in the ears venous embolic and thrombotic events arterial embolic and thrombotic events oropharyngeal pain flatulence haemorrhoids glossodynia hyperbilirubinaemia itchiness erythema hair loss myalgia kidney failure increased lipase increases alanine aminotransferase increased amylase increased aspartate aminotransferase increased alkaline phosphatase increased creatinine uncommon uncommon (0.1–1% incidence) adverse effects include: gastrointestinal perforation and fistula reversible posterior leucoencephalopathy syndrome polycythaemia