were too weak to clean themselves, which have since been condemned by healthcare professionals and medical organizations such as the college of french gynecologists and obstetricians. hyperemesis gravidarum is estimated to cost us$3 billion per year for hospitalization costs alone, not including the direct medical costs of additional outpatient medical appointments, prescription drugs, and home health care, or any indirect costs such as lost work. in the 15 years between 2007 and 2023, the us national institutes of health approved six research grants to study hyperemesis gravidarum, with a total of us$2.1 million dollars in research funding for all six grants combined (an average of $350,000 per grant or $140,000 per year).