lofendazam lofendazam lofendazam is an organic molecule which is a benzodiazepine derivative. lofendazam is a 1,5-benzodiazepine, with the nitrogen atoms located at positions 1 and 5 of the diazepine ring; therefore, lofendazam is most closely related to other 1,5-benzodiazepines such as clobazam. lofendazamclinical dataatc codenoneidentifiers iupac name 8-chloro-1-phenyl-1,3,4,5-tetrahydro- 2h-1,5-benzodiazepin- 2-one cas number29176-29-2 ypubchem cid71709chemspider64759 yuniiv7o53s50sncomptox dashboard (epa)dtxsid30183436 echa infocard100.044.975 chemical and physical dataformulac15h13cln2omolar mass272.73 g·mol−13d model (jsmol)interactive image smiles clc3ccc1c(n(c(=o)ccn1)c2ccccc2)c3 inchi inchi=1s/c15h13cln2o/c16-11-6-7-13-14(10-11)18(15(19)8-9-17-13)12-4-2-1-3-5-12/h1-7,10,17h,8-9h2 ykey:iujqouhdfkalcy-uhfffaoysa-n y (verify) lofendazam as a human pharmaceutical has sedative and anxiolytic effects similar to those produced by other benzodiazepine derivatives. it is an active metabolite of another benzodiazepine, arfendazam.