3β-methoxypregnenolone 3β-methoxypregnenolone 3β-methoxypregnenolone (developmental code name map-4343), or pregnenolone 3β-methyl ether, also known as 3β-methoxypregn-5-en-20-one, is a synthetic neuroactive steroid and derivative of pregnenolone. it interacts with microtubule-associated protein 2 (map2) in a similar manner to pregnenolone and is under development for potential clinical use for indications such as the treatment of brain and spinal cord injury and depressive disorders. 3β-methoxypregnenoloneclinical dataother namespregnenolone 3-methyl ether; 3β-methoxypregn-5-en-20-oneidentifiers iupac name 1-phenanthren-17-yl]ethanone cas number511-26-2pubchem cid233254chemspider203358uniitu767rk7ynchemical and physical dataformulac22h34o2molar mass330.512 g·mol−13d model (jsmol)interactive image smiles cc(=o)1cc21(cc32cc=c43(cc(c4)oc)c)c inchi inchi=1s/c22h34o2/c1-14(23)18-7-8-19-17-6-5-15-13-16(24-4)9-11-21(15,2)20(17)10-12-22(18,19)3/h5,16-20h,6-13h2,1-4h3/t16-,17-,18+,19-,20-,21-,22+/m0/s1key:zvgqoqhamhmmne-bibixiovsa-n