leconotide leconotide leconotide (inn; development codes cnsb004 and am336; also known as ω-conotoxin cvid) is an ω-conotoxin peptide isolated from the venom of conus catus which is under investigation as an analgesic drug for the treatment of pain conditions. leconotideclinical dataroutes ofadministrationivatc codenoneidentifierscas number247207-64-3pubchem cid16132255chemspider17288914unii2p1p5jb93scomptox dashboard (epa)dtxsid30179455 chemical and physical dataformulac107h179n35o36s7molar mass2756.24 g·mol−1 it acts as an n-type voltage-gated calcium channel (cav2.2) blocker and is highly selective for this channel over the related p/q-type voltage-gated calcium channel (cav2.1). relative to ziconotide, leconotide is advantageous in that it is significantly less toxic, and for that reason can be administered intravenously as opposed to via intrathecal injection.