5-methoxy-7,n,n-trimethyltryptamine 5-methoxy-7,n,n-trimethyltryptamine 5-methoxy-7,n,n-trimethyltryptamine (5-meo-7,n,n-tmt, 5-meo-7-tmt), is a tryptamine derivative which acts as an agonist at the 5-ht2 serotonin receptors. in animal tests, both 7,n,n-tmt and 5-meo-7,n,n-tmt produced behavioural responses similar to those of psychedelic drugs such as dmt and 5-meo-dmt, but compounds with larger 7-position substituents such as 7-ethyl-dmt and 7-bromo-dmt did not produce psychedelic-appropriate responding despite high 5-ht2 receptor binding affinity, suggesting these may be antagonists or weak partial agonists for the 5-ht2 receptors. the related compound 7-meo-mipt (cf. 5-meo-mipt) was also found to be inactive, suggesting that the 7-position has poor tolerance for bulky groups at this position, at least if agonist activity is desired. 5-methoxy-7,n,n-trimethyltryptamineidentifiers iupac name 2-(5-methoxy-7-methyl-1h-indol-3-yl)-n,n-dimethylethanamine cas number61018-77-7 n freebase 74798-76-8 oxalate saltpubchem cid12338919chemspider10578304 ychemblchembl20243 ycomptox dashboard (epa)dtxsid40491731 chemical and physical dataformulac14h20n2omolar mass232.327 g·mol−13d model (jsmol)interactive image smiles cc1=c(nc=c2ccn(c)c)c2=cc(oc)=c1 inchi inchi=1s/c14h20n2o/c1-10-7-12(17-4)8-13-11(5-6-16(2)3)9-15-14(10)13/h7-9,15h,5-6h2,1-4h3 ykey:ygaomgvuiwnfmd-uhfffaoysa-n y ny (what is this?) (verify)