hepatic porphyria hepatic porphyria hepatic porphyrias is a form of porphyria in which toxic porphyrin molecules build up in the liver. hepatic porphyrias can result from a number of different enzyme deficiencies. hepatic porphyriaspecialtyendocrinology examples include (in order of synthesis pathway): acute intermittent porphyria porphyria cutanea tarda and hepatoerythropoietic porphyria hereditary coproporphyria variegate porphyria