propentofylline propentofylline propentofylline (hwa 285) is a xanthine derivative drug with purported neuroprotective effects. propentofyllineclinical dataahfs/drugs.cominternational drug namesatc coden06bc02 (who) qc04ad90 (who)identifiers iupac name 3-methyl-1-(5-oxohexyl)-7-propyl-3,7-dihydro-1h-purine-2,6-dione cas number55242-55-2 ypubchem cid4938chemspider4769unii5rta398u4hcomptox dashboard (epa)dtxsid4045189 echa infocard100.133.568 chemical and physical dataformulac15h22n4o3molar mass306.366 g·mol−13d model (jsmol)interactive image smiles cccn1cnc2c1c(=o)n(c(=o)n2c)ccccc(=o)c inchi inchi=1s/c15h22n4o3/c1-4-8-18-10-16-13-12(18)14(21)19(15(22)17(13)3)9-6-5-7-11(2)20/h10h,4-9h2,1-3h3key:rbqoqrrfdpxagn-uhfffaoysa-n (verify) pharmacology it is a phosphodiesterase inhibitor, and also acts as an adenosine reuptake inhibitor. uses propentofylline was studied as a possible treatment for alzheimer's disease and multi-infarct dementia, and has been studied, to a lesser extent, as a possible adjunct in the treatment of ischemic stroke, due to its vasodilating properties. propentofylline is in use as a veterinary medicine in older dogs.