buclizine buclizine buclizine is an antihistamine and anticholinergic of the diphenylmethylpiperazine group. it is considered to be an antiemetic, similar to meclizine. buclizineclinical dataahfs/drugs.commicromedex detailed consumer informationatc coder06ae01 (who) identifiers iupac name (rs)-1--4- piperazine cas number82-95-1 ypubchem cid6729iuphar/bps7134drugbankdb00354 ychemspider6473 yunii0c94v6x681chebichebi:3205 ychemblchembl1201271 ncomptox dashboard (epa)dtxsid0022694 echa infocard100.001.317 chemical and physical dataformulac28h33cln2molar mass433.04 g·mol−13d model (jsmol)interactive imagechiralityracemic mixture smiles clc1ccc(cc1)c(c2ccccc2)n3ccn(cc3)cc4ccc(cc4)c(c)(c)c inchi inchi=1s/c28h33cln2/c1-28(2,3)25-13-9-22(10-14-25)21-30-17-19-31(20-18-30)27(23-7-5-4-6-8-23)24-11-15-26(29)16-12-24/h4-16,27h,17-21h2,1-3h3 ykey:moygzhxdrjnjep-uhfffaoysa-n y ny (what is this?) (verify) in the united kingdom, buclizine is one of three drugs contained in migraleve tablets, marketed by mcneil healthcare for migraines.