tiotixene tiotixene tiotixene, or thiothixene, sold under the brand name navane among others, is a typical antipsychotic of the thioxanthene class which is related to chlorprothixene and is used in the treatment of psychoses like schizophrenia and bipolar mania. it was introduced in the united states in 1967 by pfizer. tiotixeneclinical datatrade namesnavaneother namesthiothixene (usan us)ahfs/drugs.commonographmedlineplusa682867pregnancycategory au: b1 routes ofadministrationby mouthdrug classtypical antipsychoticatc coden05af04 (who) legal statuslegal status au: s4 (prescription only) in general: ℞ (prescription only) pharmacokinetic datametabolismhepaticelimination half-life10–20 hoursidentifiers iupac name (9z)-n,n-dimethyl-9--9h-thioxanthene-2-sulfonamide cas number3313-26-6 ypubchem cid941651iuphar/bps212drugbankdb01623 ychemspider819430 yunii7318fj13yjkeggd00374chemblchembl1201 ycomptox dashboard (epa)dtxsid2091542 echa infocard100.233.356 chemical and physical dataformulac23h29n3o2s2molar mass443.62 g·mol−13d model (jsmol)interactive image smiles o=s(=o)(n(c)c)c2cc1c(\c3c(sc1cc2)cccc3)=c/ccn4ccn(c)cc4 inchi inchi=1s/c23h29n3o2s2/c1-24(2)30(27,28)18-10-11-23-21(17-18)19(20-7-4-5-9-22(20)29-23)8-6-12-26-15-13-25(3)14-16-26/h4-5,7-11,17h,6,12-16h2,1-3h3/b19-8- ykey:gfbkorzttchdgy-uwvjohfnsa-n y (verify) tiotixene is also related to thioproperazine and pipotiazine, members of the phenothiazine class. pharmacology pharmacodynamics