otilonium bromide otilonium bromide otilonium bromide, sold under the trade name spasmomen among others, is an antimuscarinic and calcium channel blocker used to relieve spasmodic pain of the gut, especially in irritable bowel syndrome. otilonium bromideclinical datatrade namesspasmoctyl 40, doralinahfs/drugs.cominternational drug namesatc codea03ab06 (who) identifiers iupac name n,n-diethyl-n-methyl-2-(4-benzoyloxy)ethanaminium bromide cas number26095-59-0 ypubchem cid72092chemspider65077 nunii21hn3n72pvkeggd07083 ycomptox dashboard (epa)dtxsid0046357 echa infocard100.043.128 chemical and physical dataformulac29h43brn2o4molar mass563.577 g·mol−13d model (jsmol)interactive image smiles ccccccccoc1=cc=cc=c1c(=o)nc2=cc=c(c=c2)c(=o)occ(c)(cc)cc. inchi inchi=1s/c29h42n2o4.brh/c1-5-8-9-10-11-14-22-34-27-16-13-12-15-26(27)28(32)30-25-19-17-24(18-20-25)29(33)35-23-21-31(4,6-2)7-3;/h12-13,15-20h,5-11,14,21-23h2,1-4h3;1h nkey:vwzpijgxywhbow-uhfffaoysa-n n ny (what is this?) (verify) medical uses a pooled analysis of three clinical trials suggest that otilonium is more effective than placebo for the treatment of irritable bowel syndrome. pharmacology otilinium binds to both muscarinic receptors and tachykinin nk2 receptors. it has been shown to inhibit l-type and t-type calcium channels, actions which may contribute to or determine its effects in the gut. when taken orally, very little of the drug is absorbed into the rest of the body, which means that most of its actions remain confined to the gastrointestinal system.