cimicoxib cimicoxib cimicoxib (ur-8880 trade name cimalgex) is a nonsteroidal anti-inflammatory drug (nsaid) used in veterinary medicine to treat dogs for pain and inflammation associated with osteoarthritis and for the management of pain and inflammation associated with surgery. it acts as a cox-2 inhibitor. cimicoxib names preferred iupac name 4-benzene-1-sulfonamide identifiers cas number 265114-23-6 y 3d model (jsmol) interactive image chebi chebi:76127 chembl chembl435381 chemspider 184745 echa infocard 100.170.774 pubchem cid 213053 unii w7fhj107mc y comptox dashboard (epa) dtxsid30181093 inchi inchi=1s/c16h13clfn3o3s/c1-24-14-7-2-10(8-13(14)18)15-16(17)20-9-21(15)11-3-5-12(6-4-11)25(19,22)23/h2-9h,1h3,(h2,19,22,23)key: kyxdnecmrlfqmz-uhfffaoysa-ninchi=1/c16h13clfn3o3s/c1-24-14-7-2-10(8-13(14)18)15-16(17)20-9-21(15)11-3-5-12(6-4-11)25(19,22)23/h2-9h,1h3,(h2,19,22,23)key: kyxdnecmrlfqmz-uhfffaoyaq smiles o=s(=o)(c3ccc(n1c(c(cl)nc1)c2ccc(oc)c(f)c2)cc3)n properties chemical formula c16h13clfn3o3s molar mass 381.81 g·mol−1 pharmacology atcvet code qm01ah93 (who) except where otherwise noted, data are given for materials in their standard state (at 25 °c , 100 kpa). infobox references synthesis cimicoxib synthesis: reaction of the imine with tosmic in the presence of potassium carbonate leads to what may be viewed as 2+3 cycloaddition of the nitrogen analogue of a ketene to form the imidazole ring.