gangliosidosis gangliosidosis gangliosidosis contains different types of lipid storage disorders caused by the accumulation of lipids known as gangliosides. there are two distinct genetic causes of the disease. both are autosomal recessive and affect males and females equally. gangliosidosisspecialtyendocrinology types gm1 gangliosidoses - gm1 gm2 gangliosidoses - gm2