gliquidone gliquidone gliquidone (inn, sold under the trade name glurenorm) is an anti-diabetic medication in the sulfonylurea class. it is classified as a second-generation sulfonylurea. it is used in the treatment of diabetes mellitus type 2. it is marketed by the pharmaceutical company boehringer ingelheim (germany). gliquidoneclinical datatrade namesglurenormahfs/drugs.cominternational drug namespregnancycategory c routes ofadministrationoral (tablets)atc codea10bb08 (who) legal statuslegal status uk: pom (prescription only) in general: ℞ (prescription only) pharmacokinetic databioavailabilityhigh (tmax = 2–3 hours)metabolismextensive hepaticonset of action1–1.5 hoursexcretionbiliary (95%), renal (5%)identifiers iupac name 1-cyclohexyl-3-phenyl]sulfonylurea cas number33342-05-1pubchem cid91610drugbankdb01251 ychemspider82719 yuniic7c2qdd75pkeggd02430 ychemblchembl383634 ycomptox dashboard (epa)dtxsid4023096 echa infocard100.046.770 chemical and physical dataformulac27h33n3o6smolar mass527.64 g·mol−13d model (jsmol)interactive image smiles o=c(nc1ccccc1)ns(=o)(=o)c2ccc(cc2)ccn4c(=o)c3c(ccc(oc)c3)c(c4=o)(c)c inchi inchi=1s/c27h33n3o6s/c1-27(2)23-14-11-20(36-3)17-22(23)24(31)30(25(27)32)16-15-18-9-12-21(13-10-18)37(34,35)29-26(33)28-19-7-5-4-6-8-19/h9-14,17,19h,4-8,15-16h2,1-3h3,(h2,28,29,33) ykey:lljfmfzyvvlqkt-uhfffaoysa-n y (verify) contraindications allergy to sulfonylureas or sulfonamides diabetes mellitus type 1 diabetic ketoacidosis patients that underwent removal of the pancreas acute porphyria severe liver disease accompanying with liver insufficiency several conditions (e.g., infectious diseases or major surgical intervention), when insulin administration is required pregnancy or breastfeeding pharmacokinetics gliquidone is fully metabolized by the liver. its metabolites are excreted virtually completely with bile (even with long-term administration), thus allowing the use of medication in diabetic patients with kidney disease and diabetic nephropathy.