mmb-2201 mmb-2201 mmb-2201 (also known as 5f-mmb-pica, 5f-amb-pica, and i-amb) is a potent indole-3-carboxamide based synthetic cannabinoid, which has been sold as a designer drug and as an active ingredient in synthetic cannabis blends. it was first reported in russia and belarus in january 2014, but has since been sold in a number of other countries. in the united states, mmb-2201 was identified in drug enforcement administration drug seizures for the first time in 2018. mmb-2201legal statuslegal status ca: schedule ii de: anlage ii (authorized trade only, not prescriptible) uk: class b identifiers iupac name (s)-methyl 2-(1-(5-fluoropentyl)-1h-indole-3-carboxamido)-3-methylbutanoate cas number1616253-26-9pubchem cid119058037chemspider30922499unii744m0whe80chemical and physical dataformulac20h27fn2o3molar mass362.445 g·mol−13d model (jsmol)interactive image smiles cc(c)(c(=o)oc)nc(=o)c1cn(c2c1cccc2)cccccf inchi inchi=1s/c20h27fn2o3/c1-14(2)18(20(25)26-3)22-19(24)16-13-23(12-8-4-7-11-21)17-10-6-5-9-15(16)17/h5-6,9-10,13-14,18h,4,7-8,11-12h2,1-3h3,(h,22,24)/t18-/m0/s1key:jfxasafvuqvgew-sfhvurjksa-n mmb-2201 is the indole core analogue of 5f-amb. synthetic cannabinoid compounds with an indole-3-carboxamide or indazole-3-carboxamide core bearing a n-1-methoxycarbonyl group with attached isopropyl or tert-butyl substituent, have proved to be much more dangerous than older synthetic cannabinoid compounds previously reported, and have been linked to many deaths in russia, japan, europe and the united states. legality mmb-2201 is illegal in russia, belarus and sweden.