the monarch initiative the monarch initiative the monarch initiative is a large scale bioinformatics web resource focused on leveraging existing biomedical knowledge to connect genotypes with phenotypes in an effort to aid research that combats genetic diseases. monarch does this by integrating multi-species genotype, phenotype, genetic variant and disease knowledge from various existing biomedical data resources into a centralized and structured database. while this integration process has been traditionally done manually by basic researchers and clinicians on a case-by-case basis, the monarch initiative provides an aggregated and structured collection of data and tools that make biomedical knowledge exploration more efficient and effective. the monarch initiativecontentdescriptionbioinformatics database of genetic disease datadata typescapturedgenotype, phenotype, variant, disease, speciesorganismsmetazoacontactprimary citationmungall et al. 2017release datejuly 12, 2015accesswebsitehttps://monarchinitiative.org mondo ontology mondo ontology is product of the monarch initiative. it provides ontology for diseases and disorders, both rare and common.