stepholidine stepholidine (−)-stepholidine is a protoberberine alkaloid found in the plant stephania intermedia. (−)-stepholidine names iupac name 3,9-dimethoxyberbine-2,10-diol systematic iupac name (13as)-3,9-dimethoxy-5,8,13,13a-tetrahydro-6h-isoquinolinoisoquinoline-2,10-diol other names l-stepholidine identifiers cas number 16562-13-3 y 3d model (jsmol) interactive image chembl chembl487387 n chemspider 5293188 n mesh stepholidine pubchem cid 6917970 unii 0upx3e69w8 y comptox dashboard (epa) dtxsid70937112 inchi inchi=1s/c19h21no4/c1-23-18-8-12-5-6-20-10-14-11(3-4-16(21)19(14)24-2)7-15(20)13(12)9-17(18)22/h3-4,8-9,15,21-22h,5-7,10h2,1-2h3/t15-/m0/s1 nkey: jkpisqiiwuonpb-hnnxbmfysa-n ninchi=1/c19h21no4/c1-23-18-8-12-5-6-20-10-14-11(3-4-16(21)19(14)24-2)7-15(20)13(12)9-17(18)22/h3-4,8-9,15,21-22h,5-7,10h2,1-2h3/t15-/m0/s1key: jkpisqiiwuonpb-hnnxbmfybd smiles coc1=c(c=c23cc4=c(cn3ccc2=c1)c(=c(c=c4)o)oc)o properties chemical formula c19h21no4 molar mass 327.374 g/mol except where otherwise noted, data are given for materials in their standard state (at 25 °c , 100 kpa). n verify (what is yn ?) infobox references stepholidine activity includes dual d2 receptor antagonist and d1 receptor agonist, and has shown antipsychotic activity in animal studies.