multifocal lymphangioendotheliomatosis multifocal lymphangioendotheliomatosis multifocal lymphangioendotheliomatosis, also known as congenital cutaneovisceral angiomatosis with thrombocytopenia, and multifocal lymphangioendotheliomatosis with thrombocytopenia, is a skin condition that presents at birth with hundreds of red-brown plaques as large as several centimeters.: 596