bis-gma bis-gma bis-gma (bisphenol a-glycidyl methacrylate) is a resin commonly used in dental composite, dental sealants. and dental cement. it is the diester derived from methacrylic acid and the bisphenol a diglycidyl ether. bearing two polymerizable groups, it is prone to form a crosslinked polymer that is used in dental restorations. for dental work, highly viscous bis-gma is mixed with aluminosilicate particles, crushed quartz and other related acrylates; changes to component ratios lead to different physical properties in the end product. bis-gma was incorporated into composite dental resins in 1962 by rafael bowen. until matrix development work in the early 2000s, bis-gma and related methacrylate monomers were the only options for organic matrix composition. bis-gma names preferred iupac name propane-2,2-diylbis bis(2-methylprop-2-enoate) other names bowen monomer; silux; delton; nuvaseal; retroplast identifiers cas number 1565-94-2 y 3d model (jsmol) interactive image chemspider 14549 echa infocard 100.014.880 ec number 216-367-7 pubchem cid 15284 unii 454i75yxy0 y comptox dashboard (epa) dtxsid7044841 inchi inchi=1s/c29h36o8/c1-19(2)27(32)36-17-23(30)15-34-25-11-7-21(8-12-25)29(5,6)22-9-13-26(14-10-22)35-16-24(31)18-37-28(33)20(3)4/h7-14,23-24,30-31h,1,3,15-18h2,2,4-6h3key: amfgwxwbfgvckg-uhfffaoysa-n smiles cc(=c)c(=o)occ(coc1=cc=c(c=c1)c(c)(c)c2=cc=c(c=c2)occ(coc(=o)c(=c)c)o)o properties chemical formula c29h36o8 molar mass 512.599 g·mol−1 appearance colorless oil hazards ghs labelling: pictograms signal word danger hazard statements h315, h317, h318, h319 precautionary statements p261, p264, p272, p280, p302+p352, p305+p351+p338, p310, p321, p332+p313, p333+p313, p337+p313, p362, p363, p501 except where otherwise noted, data are given for materials in their standard state (at 25 °c , 100 kpa). infobox references safety concerns have been raised about the potential for bis-gma to break down into or be contaminated with the related compound bisphenol a. however, no negative health effects of bis-gma use in dental resins have been found. composition salivary esterases can slowly degrade bis-gma-based sealants, forming bis-hppp.