elsilimomab elsilimomab elsilimomab (also known as b-e8) is a mouse monoclonal antibody. b-e8 was developed by diaclone, a french company which produces many mouse monoclonal antibodies. elsilimomabmonoclonal antibodytypewhole antibodysourcemousetargetil-6clinical dataatc codenoneidentifierscas number468715-71-1 ychemspidernoneuniidgk38a42ae ny (what is this?) (verify) it (opr-003) targets (and blocks) interleukin-6. it has undergone a number of early stage clinical trials, e.g. for lymphoma and myeloma. it was used as a template to develop a high-affinity, antagonist, fully human anti-il-6 mab 1339.