terlipressin terlipressin terlipressin, sold under the brand name terlivaz among others, is an analogue of vasopressin used as a vasoactive drug in the management of low blood pressure. it has been found to be effective when norepinephrine does not help. terlipressin is a vasopressin receptor agonist. terlipressinclinical datatrade namesterlivazahfs/drugs.cominternational drug namesroutes ofadministrationintravenousatc codeh01ba04 (who) legal statuslegal status us: ℞-only pharmacokinetic dataprotein binding~30%identifiers iupac name 1-amino)acetyl]amino}-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-l-prolyl-n-(2-amino-2-oxoethyl)-l-lysinamide cas number14636-12-5 ypubchem cid72081drugbankdb02638 ychemspider65067 yunii7z5x49w53pkeggd06672 ycomptox dashboard (epa)dtxsid7048952 echa infocard100.035.149 chemical and physical dataformulac52h74n16o15s2molar mass1227.38 g·mol−13d model (jsmol)interactive image smiles o=c(n)cnc(=o)(nc(=o)4n(c(=o)1nc(=o)(nc(=o)(nc(=o)(nc(=o)(nc(=o)(nc(=o)cnc(=o)cnc(=o)cn)cssc1)cc2ccc(o)cc2)cc3ccccc3)ccc(=o)n)cc(=o)n)ccc4)ccccn inchi inchi=1s/c52h74n16o15s2/c53-17-5-4-9-31(45(76)60-23-41(57)72)63-51(82)38-10-6-18-68(38)52(83)37-27-85-84-26-36(61-44(75)25-59-43(74)24-58-42(73)22-54)50(81)65-34(20-29-11-13-30(69)14-12-29)48(79)64-33(19-28-7-2-1-3-8-28)47(78)62-32(15-16-39(55)70)46(77)66-35(21-40(56)71)49(80)67-37/h1-3,7-8,11-14,31-38,69h,4-6,9-10,15-27,53-54h2,(h2,55,70)(h2,56,71)(h2,57,72)(h,58,73)(h,59,74)(h,60,76)(h,61,75)(h,62,78)(h,63,82)(h,64,79)(h,65,81)(h,66,77)(h,67,80)/t31-,32-,33-,34-,35-,36-,37-,38-/m0/s1 ykey:benfxaynyrlaiu-qsvfahtrsa-n y (verify) terlipressin was approved for medical use in the united states in 2022. the us food and drug administration (fda) considers it to be a first-in-class medication. medical uses terlipressin is indicated to improve kidney function in adults with hepatorenal syndrome with rapid reduction in kidney function. indications for use include norepinephrine-resistant septic shock and hepatorenal syndrome. in addition, it is used to treat bleeding esophageal varices. contraindications terlipressin is contraindicated in people experiencing hypoxia or worsening respiratory symptoms and in people with ongoing coronary, peripheral or mesenteric ischemia. terlipressin may cause fetal harm when used during pregnancy. society and culture terlipressin is available in united states, new zealand, australia, the european union, india, pakistan & uae. it is sold under various brand names including glypressin and terlivaz.