trna (cytidine56-2'-o)-methyltransferase trna (cytidine56-2'-o)-methyltransferase trna (cytidine56-2'-o)-methyltransferase (ec 2.1.1.206, atrm56, trna ribose 2'-o-methyltransferase atrm56, pab1040 (gene)) is an enzyme with systematic name s-adenosyl-l-methionine:trna (cytidine56-2'-o)-methyltransferase. this enzyme catalyses the following chemical reaction s-adenosyl-l-methionine + cytidine56 in trna ⇌ s-adenosyl-l-homocysteine + 2'-o-methylcytidine56 in trna trna (cytidine56-2'-o)-methyltransferaseidentifiersec no.2.1.1.206databasesintenzintenz viewbrendabrenda entryexpasynicezyme viewkeggkegg entrymetacycmetabolic pathwaypriamprofilepdb structuresrcsb pdb pdbe pdbsumsearchpmcarticlespubmedarticlesncbiproteins the archaeal enzyme specifically catalyses the s-adenosyl-l-methionine dependent 2'-o-ribose methylation of cytidine at position 56 in trna transcripts.