buthionine sulfoximine buthionine sulfoximine buthionine sulfoximine (bso) is a sulfoximine derivative which reduces levels of glutathione and is being investigated as an adjunct with chemotherapy in the treatment of cancer. the compound inhibits gamma-glutamylcysteine synthetase, the enzyme required in the first step of glutathione synthesis. buthionine sulfoximine may also be used to increase the sensitivity of parasites to oxidative antiparasitic drugs. buthionine sulfoximine names iupac name 2-amino-4-(butylsulfonimidoyl)butanoic acid other names bso identifiers cas number 5072-26-4 y 3d model (jsmol) interactive image chebi chebi:28714 y chemspider 19896 y echa infocard 100.156.351 mesh buthionine+sulfoximine pubchem cid 21157 unii lw4108q0bv y comptox dashboard (epa) dtxsid6044434 inchi inchi=1s/c8h18n2o3s/c1-2-3-5-14(10,13)6-4-7(9)8(11)12/h7,10h,2-6,9h2,1h3,(h,11,12) ykey: kjqfbvymgaddtq-uhfffaoysa-n yinchi=1/c8h18n2o3s/c1-2-3-5-14(10,13)6-4-7(9)8(11)12/h7,10h,2-6,9h2,1h3,(h,11,12)key: kjqfbvymgaddtq-uhfffaoyaw smiles ccccs(=n)(=o)ccc(c(=o)o)n properties chemical formula c8h18n2o3s molar mass 222.305 g/mol density 1.29 g/ml melting point 215 °c (419 °f; 488 k) boiling point 382.3 °c (720.1 °f; 655.5 k) except where otherwise noted, data are given for materials in their standard state (at 25 °c , 100 kpa). n verify (what is yn ?) infobox references