fluoroestradiol f-18 fluoroestradiol f-18 fluoroestradiol f-18, also known as 16α-fluoroestradiol and sold under the brand name cerianna, is a radioactive diagnostic agent indicated for use with positron emission tomography (pet) imaging. it is an analog of estrogen and is used to detect estrogen receptor-positive breast cancer lesions. fluoroestradiol f-18clinical datatrade namesceriannaother names16α-fluoroestradiol; 16α-fluoroestra-1,3,5(10)-triene-3,17β-diollicense data us dailymed: fluoroestradiol routes ofadministrationintravenous injectiondrug classestrogen; diagnostic radiopharmaceuticalatc codev09ix11 (who) legal statuslegal status us: ℞-only pharmacokinetic datametabolismliverexcretiongallbladder and kidneyidentifiers iupac name (8r,9s,13s,14s,16r,17r)-16-(18f)fluoranyl-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopentaphenanthrene-3,17-diol cas number94153-53-4pubchem cid10869981chemspider9045262uniit32277kb09keggd11829chemical and physical dataformulac18h23o2molar mass289.373d model (jsmol)interactive image smiles cc12ccc3c(c1cc(c2o))ccc4=c3c=cc(=c4)o inchi inchi=1s/c18h23fo2/c1-18-7-6-13-12-5-3-11(20)8-10(12)2-4-14(13)15(18)9-16(19)17(18)21/h3,5,8,13-17,20-21h,2,4,6-7,9h2,1h3/t13-,14-,15+,16-,17+,18+/m1/s1/i19-1key:kdllnmryzguvma-zymzxakxsa-n chemistry chemically, fluoroestradiol f-18 is 16α-fluoro-3,17β-diol-estratriene-1,3,5(10). history fluoroestradiol f-18 was approved for medical use in the united states in may 2020.