dexanabinol dexanabinol dexanabinol (hu-211 or ets2101) is a synthetic cannabinoid derivative in development by e-therapeutics plc. it is the "unnatural" enantiomer of the potent cannabinoid agonist hu-210. unlike other cannabinoid derivatives, hu-211 does act as a cannabinoid receptor agonist, b. it therefore does not produce cannabis-like effects, but is anticonvulsant and neuroprotective, and is widely used in scientific research as well as currently being studied for applications such as treating head injury, stroke, or cancer. it was shown to be safe in clinical trials and is currently undergoing phase i trials for the treatment of brain cancer and advanced solid tumors. dexanabinolclinical dataatc codenoneidentifiers iupac name (6as,10as)-9-(hydroxymethyl)-6,6-dimethyl-3-(2-methyloctan-2-yl)-6a,7,10,10a-tetrahydrobenzochromen-1-ol cas number112924-45-5 ypubchem cid107778drugbankdb06444 ychemspider96934 nuniir6vt8u5372chemblchembl334533comptox dashboard (epa)dtxsid40150235 echa infocard100.201.022 chemical and physical dataformulac25h38o3molar mass386.576 g·mol−13d model (jsmol)interactive image smiles oc2cc(cc1oc(3c/c=c(\c3c12)co)(c)c)c(c)(c)cccccc inchi inchi=1s/c25h38o3/c1-6-7-8-9-12-24(2,3)18-14-21(27)23-19-13-17(16-26)10-11-20(19)25(4,5)28-22(23)15-18/h10,14-15,19-20,26-27h,6-9,11-13,16h2,1-5h3/t19-,20-/m0/s1 nkey:ssqjfgmezbfmnv-pmacekpbsa-n n ny (what is this?) (verify) clinical trials dexanabinol has been studied in iv administration and oral dosing. e-therapeutics is evaluating the compound in clinical trials for brain and solid cancers. phase ii studies are planned based on the results of the current trials. a phase 1b study for hepatocellular carcinoma and pancreatic cancer was started in 2015. legal status hu-211 is not listed in the schedules set out by the united nations' single convention on narcotic drugs from 1961 nor their convention on psychotropic substances from 1971, so the signatory countries to these international drug control treaties are not required by said treaties to control hu-211. united states hu-211 is not listed in the list of scheduled controlled substances in the usa. it is therefore not scheduled at the federal level in the united states, but it is possible that hu-211 could legally be considered an analog of delta-8-thc (one of the thc isomers which is in schedule i under the designation of "tetrahydrocannabinols"), and therefore sales or possession could potentially be prosecuted under the federal analogue act. hu-211 is a schedule i controlled substance in alabama. hu-211 is a schedule i controlled substance in the state of florida making it illegal to buy, sell, or possess in florida. effective january 1, 2016, hu-211 is a regulated drug in vermont designated as a "hallucinogenic drug."