dolichol kinase deficiency dolichol kinase deficiency dolichol kinase deficiency is a cutaneous condition caused by a mutation in the dolichol kinase gene. dolichol kinase deficiencyother nameshypotonia and ichthyosis due to dolichol phosphate deficiencythis condition is inherited in an autosomal recessive manner. it is also known as congenital disorder of glycosylation 1m.