serazapine serazapine serazapine (developmental code name cgs-15040a) is a serotonin 5-ht2 receptor antagonist that was investigated as a potential treatment for generalized anxiety disorder in the 1990s. in humans, serazapine was well tolerated at doses of 10 to 40 mg and was found to be superior to placebo for reducing anxiety symptoms as indicated by ham-a scores. however, clinical development was discontinued. serazapineclinical dataother namescgs-15040aroutes ofadministrationby mouthatc codenoneidentifiers iupac name methyl 2-methyl-1,3,4,16b-tetrahydro-2h,10h-benzopyrazinodiazepinoindole-16-carboxylate cas number115313-22-9 ypubchem cid60677chemspider54685 yunii8a8fob4j3uchemblchembl2110702 nchemical and physical dataformulac22h23n3o2molar mass361.445 g·mol−13d model (jsmol)interactive image smiles o=c(oc)c1=c2n(c3=c1c=cc=c3)cc4=cc=cc=c4n5c2cn(c)cc5 inchi inchi=1s/c22h23n3o2/c1-23-11-12-24-17-9-5-3-7-15(17)13-25-18-10-6-4-8-16(18)20(22(26)27-2)21(25)19(24)14-23/h3-10,19h,11-14h2,1-2h3 ykey:wpguwabwnuspmw-uhfffaoysa-n y