caramiphen caramiphen caramiphen is an anticholinergic drug used in the treatment of parkinson's disease. in combination with phenylpropanolamine it is used as a cough suppressant and nasal decongestant to treat symptoms associated with respiratory illnesses such as cold, allergies, hay fever, and sinusitis. it was added to the british national formulary in 1963, with a dosage of 10 to 20 mg. side effects include nausea, dizziness, and drowsiness. caramiphenclinical datatrade namescarafenatc codenoneidentifiers iupac name 2-(diethylamino)ethyl 1-phenylcyclopentanecarboxylate cas number77-22-5pubchem cid6472chemspider6228unii97j7np0xjychemblchembl61946comptox dashboard (epa)dtxsid0022729 echa infocard100.000.922 chemical and physical dataformulac18h27no2molar mass289.419 g·mol−13d model (jsmol)interactive image smiles o=c(occn(cc)cc)c2(c1ccccc1)cccc2 inchi inchi=1s/c18h27no2/c1-3-19(4-2)14-15-21-17(20)18(12-8-9-13-18)16-10-6-5-7-11-16/h5-7,10-11h,3-4,8-9,12-15h2,1-2h3key:ofaigzwcdgnzgt-uhfffaoysa-n it binds to the sigma-1 receptor with an ic50 value of 25 nm. synthesis pattents: the halogenation of 1-phenylcyclopentanecarboxylic acid (1) gives 1-phenylcyclopentanecarbonyl chloride (2). ester formation with diethylaminoethanol (3) completes the synthesis of caramiphen (4).