cp-122,288 cp-122,288 cp-122,288 is a drug which acts as a potent and selective agonist for the 5-ht1b, 5-ht1d and 5-ht1f serotonin receptor subtypes. it is a derivative of the migraine medication sumatriptan, but while cp-122,288 is 40,000 times more potent than sumatriptan as an inhibitor of neurogenic inflammation and plasma protein extravasation, it is only twice as potent as a constrictor of blood vessels. in human trials, cp-122,288 was not found to be effective as a treatment for migraine, but its selectivity for neurogenic anti-inflammatory action over vasoconstriction has made it useful for research into the underlying causes of migraine. cp-122,288identifiers iupac name n-methyl-1-methyl)-1h-indol-5-yl]methanesulfonamide cas number143321-74-8 ypubchem cid132552iuphar/bps110chemspider117032unii59e9wct6emcomptox dashboard (epa)dtxsid00931820 chemical and physical dataformulac16h23n3o2smolar mass321.44 g·mol−13d model (jsmol)interactive image smiles cns(=o)(=o)cc1ccc2c(c1)c(c2)c3cccn3c inchi inchi=1s/c16h23n3o2s/c1-17-22(20,21)11-12-5-6-16-15(8-12)13(10-18-16)9-14-4-3-7-19(14)2/h5-6,8,10,14,17-18h,3-4,7,9,11h2,1-2h3/t14-/m1/s1key:bwqzthphlitooz-cqszacivsa-n