hexobendine hexobendine hexobendine is a vasodilator that acts as an adenosine reuptake inhibitor. hexobendineclinical dataatc codec01dx06 (who) identifiers iupac name ethane-1,2-diylbis bis(3,4,5-trimethoxybenzoate) cas number54-03-5 npubchem cid5777chemspider5573 nuniib6x4syr93bcomptox dashboard (epa)dtxsid20202302 echa infocard100.000.173 chemical and physical dataformulac30h44n2o10molar mass592.686 g·mol−13d model (jsmol)interactive image smiles coc1c(cc(cc1oc)c(=o)occcn(c)ccn(c)cccoc(=o)c2cc(oc)c(oc)c(oc)c2)oc inchi inchi=1s/c30h44n2o10/c1-31(11-9-15-41-29(33)21-17-23(35-3)27(39-7)24(18-21)36-4)13-14-32(2)12-10-16-42-30(34)22-19-25(37-5)28(40-8)26(20-22)38-6/h17-20h,9-16h2,1-8h3 nkey:krqamfqcsajcrh-uhfffaoysa-n n ny (what is this?) (verify) synthesis hexobendine can be synthesized starting with a reaction between 3,4,5-trimethoxybenzoyl chloride (1) and 3-chloropropanol (2) to give the corresponding ester, 3-chloropropyl 3,4,5-trimethoxybenzoate (3). the last step involves the reaction between two molar equivalents of 3 with one molar equivalent of 1,2-dimethylethylenediamine (4) completing the synthesis of hexobendine (5). synthesis of hexobendine