aminosteroid aminosteroid aminosteroids are a group of steroids with a similar structure based on an amino-substituted steroid nucleus. they are neuromuscular blocking agents, acting as competitive antagonists of the nicotinic acetylcholine receptor (nachr), and block the signaling of acetylcholine in the nervous system. these drugs include candocuronium iodide (chandonium iodide), dacuronium bromide, dihydrochandonium, dipyrandium, malouetine, pancuronium bromide, pipecuronium bromide, rapacuronium bromide, rocuronium bromide, stercuronium iodide, and vecuronium bromide. pancuronium, the first aminosteroid neuromuscular blocking agent to be introduced.