imep (chemotherapy) imep (chemotherapy) imep is a chemotherapy regimen that is effective for nasal nk- / t-cell lymphoma. this chemotherapy regimen was also tested in hodgkin disease as a part of a multidrug alternating scheme copp / abv / imep. but in that setting it showed no advantage in efficacy and toxicity compared to the use of abvd or the alternating copp / abvd scheme. drug regimen drugdosemodedays (i)fosfamide1500 mg/m2 with mesnaiv infusiondays 1-3 (m)ethotrexate30 mg/m2iv bolusdays 3 and 10 (e)toposide100 mg/m2iv infusiondays 1-3 (p)rednisone120 mgpo qddays 1-5