serlopitant serlopitant serlopitant (inn, codenamed vpd-737) is a drug which acts as an nk1 receptor antagonist. it was assessed in clinical trials for the treatment of urinary incontinence and overactive bladder, but while it was superior to placebo it provided no advantage over existing approved drugs, and was not approved for further development for this indication. serlopitant is now undergoing clinical trials for the treatment of chronic pruritus (itch) serlopitantclinical dataroutes ofadministrationby mouthatc codenoneidentifiers iupac name 3-ethoxy}-4-(4-fluorophenyl)octahydro-2h-isoindol-2-yl]cyclopent-2-en-1-one cas number860642-69-9pubchem cid23653789chemspider24686685unii277v92k32bkeggd09378chemblchembl447955comptox dashboard (epa)dtxsid701006599 chemical and physical dataformulac29h28f7no2molar mass555.537 g·mol−13d model (jsmol)interactive image smiles c(c1=cc(=cc(=c1)c(f)(f)f)c(f)(f)f)o2cc3cn(c32c4=cc=c(c=c4)f)c5=cc(=o)cc5 inchi inchi=1s/c29h28f7no2/c1-16(19-10-20(28(31,32)33)12-21(11-19)29(34,35)36)39-26-9-4-18-14-37(23-7-8-24(38)13-23)15-25(18)27(26)17-2-5-22(30)6-3-17/h2-3,5-6,10-13,16,18,25-27h,4,7-9,14-15h2,1h3/t16-,18-,25-,26+,27+/m1/s1key:flnycrjbcnnhrh-oiyljqicsa-n