coenzyme q10 deficiency coenzyme q10 deficiency coenzyme q10 deficiency is a deficiency of coenzyme q10. coenzyme q10 deficiencyother namesleigh syndrome with nephrotic syndromeubiquinone it can be associated with coq2, aptx, pdss2, pdss1, cabc1, and coq9. some forms may be more treatable than other mitochondrial diseases.