estriol phosphate estriol phosphate estriol phosphate (e3p), or estriol 17β-phosphate, also known as estra-1,3,5(10)-triene-3,16α,17β-triol 17β-(dihydrogen phosphate), is an estrogen which was never marketed. it is an estrogen ester, specifically an ester of estriol with phosphoric acid, and acts as a prodrug of estriol by cleavage via phosphatase enzymes in the body. estriol phosphate is contained within the chemical structure of polyestriol phosphate (a polymer of estriol phosphate), and this medication has been marketed for medical use (brand names gynäsan, klimadurin, triodurin). not to be confused with polyestriol phosphate. estriol phosphateclinical dataother namese3p; estriol 17β-phosphate; estra-1,3,5(10)-triene-3,16α,17β-triol 17β-(dihydrogen phosphate); 3,16α-diydroxyestra-1,3,5(10)-trien-17β-yl phosphatedrug classestrogen; estrogen esteridentifiers iupac name (8r,9s,13s,14s,16r,17r)-3,16-dihydroxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6h-cyclopentaphenanthren-17-yl dihydrogen phosphate cas number35973-57-0 yuniifq5fv85bs0chemical and physical dataformulac18h25o6pmolar mass368.366 g·mol−13d model (jsmol)interactive image smiles c1((c2o)()3()(c4=c(cc3)c=c(c=c4)o)()cc1)2op(o)(o)=o inchi inchi=1s/c18h25o6p/c1-18-7-6-13-12-5-3-11(19)8-10(12)2-4-14(13)15(18)9-16(20)17(18)24-25(21,22)23/h3,5,8,13-17,19-20h,2,4,6-7,9h2,1h3,(h2,21,22,23)/t13-,14-,15+,16-,17+,18+/m1/s1key:hnkvqsmsafuelq-zxxigwhrsa-n