hematologic disease hematologic disease hematologic diseases are disorders which primarily affect the blood & blood-forming organs. hematologic diseases include rare genetic disorders, anemia, hiv, sickle cell disease & complications from chemotherapy or transfusions. hematologic diseasespecialtyhematology myeloid hemoglobinopathies (congenital abnormality of the hemoglobin molecule or of the rate of hemoglobin synthesis) sickle cell disease thalassemia methemoglobinemia anemias (lack of red blood cells or hemoglobin) iron-deficiency anemia megaloblastic anemia vitamin b12 deficiency pernicious anemia folate deficiency hemolytic anemias (destruction of red blood cells) genetic disorders of rbc membrane hereditary spherocytosis hereditary elliptocytosis congenital dyserythropoietic anemia genetic disorders of rbc metabolism glucose-6-phosphate dehydrogenase deficiency (g6pd) pyruvate kinase deficiency immune mediated hemolytic anemia (direct coombs test is positive) autoimmune hemolytic anemia warm antibody autoimmune hemolytic anemia idiopathic systemic lupus erythematosus (sle) evans syndrome (antiplatelet antibodies and hemolytic antibodies) cold autoimmune hemolytic anemia cold agglutinin disease paroxysmal cold hemoglobinuria (rare) infectious mononucleosis alloimmune hemolytic anemia hemolytic disease of the newborn (hdn) rh disease (rh d) abo hemolytic disease of the newborn anti-kell hemolytic disease of the newborn rhesus c hemolytic disease of the newborn rhesus e hemolytic disease of the newborn other blood group incompatibility (rhc, rhe, kid, duffy, mn, p and others) drug induced immune mediated hemolytic anemia penicillin (high dose) methyldopa hemoglobinopathies (where these is an unstable or crystalline hemoglobin) paroxysmal nocturnal hemoglobinuria (rare acquired clonal disorder of red blood cell surface proteins) direct physical damage to rbcs microangiopathic hemolytic anemia secondary to artificial heart valve(s) aplastic anemia fanconi anemia diamond–blackfan anemia (inherited pure red cell aplasia) acquired pure red cell aplasia decreased numbers of cells myelodysplastic syndrome myelofibrosis neutropenia (decrease in the number of neutrophils) agranulocytosis glanzmann's thrombasthenia thrombocytopenia (decrease in the number of platelets) idiopathic thrombocytopenic purpura (itp) thrombotic thrombocytopenic purpura (ttp) heparin-induced thrombocytopenia (hit) myeloproliferative disorders (increased numbers of cells) polycythemia vera (increase in the number of cells in general) erythrocytosis (increase in the number of red blood cells) leukocytosis (increase in the number of white blood cells) thrombocytosis (increase in the number of platelets) myeloproliferative disorder transient myeloproliferative disease coagulopathies (disorders of bleeding and coagulation) thrombocytosis recurrent thrombosis disseminated intravascular coagulation disorders of clotting proteins hemophilia hemophilia a hemophilia b (also known as christmas disease) hemophilia c von willebrand disease disseminated intravascular coagulation protein s deficiency antiphospholipid syndrome disorders of platelets thrombocytopenia glanzmann's thrombasthenia wiskott–aldrich syndrome hematological malignancies hematological malignancies lymphomas hodgkin's disease non-hodgkin's lymphoma burkitt's lymphoma anaplastic large cell lymphoma splenic marginal zone lymphoma hepatosplenic t-cell lymphoma angioimmunoblastic t-cell lymphoma (ailt) myelomas multiple myeloma waldenström macroglobulinemia plasmacytoma leukemias increased wbc acute lymphocytic leukemia (all) chronic lymphocytic leukemia (cll) acute myelogenous leukemia (aml) acute megakaryoblastic leukemia (amkl), a sub-type of acute myelogenous leukemia chronic idiopathic myelofibrosis (mf) chronic myelogenous leukemia (cml) t-cell prolymphocytic leukemia (t-pll) b-cell prolymphocytic leukemia (b-pll) chronic neutrophilic leukemia (cnl) hairy cell leukemia (hcl) t-cell large granular lymphocyte leukemia (t-lgl) aggressive nk-cell leukemia miscellaneous hemochromatosis asplenia hypersplenism gaucher's disease monoclonal gammopathy of undetermined significance hemophagocytic lymphohistiocytosis tempi syndrome hematological changes secondary to non-hematological disorders anemia of chronic disease infectious mononucleosis aids malaria leishmaniasis