25i-nboh 25i-nboh 25i-nboh (nboh-2ci, cimbi-27, 2-c-i-nboh) is a derivative of the phenethylamine-derived hallucinogen 2c-i that was discovered in 2006 by a team at purdue university. 25i-nbohlegal statuslegal status de: npsg (industrial and scientific use only) uk: class a identifiers iupac name 2-((2-(4-iodo-2,5-dimethoxyphenyl)ethylamino)methyl)phenol cas number919797-20-9 ypubchem cid10001761chemspider8177342 yuniiw9g4bgw8k4comptox dashboard (epa)dtxsid80433993 chemical and physical dataformulac17h20ino3molar mass413.255 g·mol−13d model (jsmol)interactive image smiles oc2ccccc2cnccc(c(oc)cc1i)cc1oc inchi inchi=1s/c17h20ino3/c1-21-16-10-14(18)17(22-2)9-12(16)7-8-19-11-13-5-3-4-6-15(13)20/h3-6,9-10,19-20h,7-8,11h2,1-2h3 ykey:feuzhyrxgqtbro-uhfffaoysa-n y ny (what is this?) (verify) pharmacology 25i-nboh acts as a potent agonist of the 5ht2a receptor, with a ki of 0.061 nm at the human 5ht2a receptor, similar to the better-known compound 25i-nbome, making it some twelve times the potency of 2c-i itself. although in vitro tests show this compound acts as an agonist, animal studies to confirm these findings have not been reported. while the n-benzyl derivatives of 2c-i had significantly increased binding to 5ht2a receptor fragments, compared to 2c-i, the n-benzyl derivatives of doi were less active compared to doi. 25i-nboh is notable as one of the most selective agonist ligands for the 5-ht2a receptor with an ec50 value of 0.074 nm with more than 400 times selectivity over the 5-ht2c receptor. analytical chemistry 25i-nboh is a labile molecule which fragments into 2c-i when analyzed by routine gas chromatography (gc) methods. a specific method for reliable identification of 25i-nboh using gc/ms has been reported, allowing forensic forces worldwide to correctly identify this compound. legality sweden the riksdag added 25i-nboh to narcotic drugs punishments act under swedish schedule i ("substances, plant materials and fungi which normally do not have medical use") as of august 18, 2015, published by medical products agency mpa) in regulation hslf-fs 2015:12 listed as "25i-nboh" and "2-(metyl)fenol". united kingdom this substance is a class a drug in the united kingdom as a result of the n-benzylphenethylamine catch-all clause in the misuse of drugs act 1971. analogues and derivatives analogues and derivatives of 2c-i: 25i-nb*: 25i-nbf 25i-nbmd 25i-nb34md 25i-nboh 25i-nbome (nbome-2ci) 25i-nb3ome 25i-nb4ome n-(2c)-fentanyl: n-(2c-i) fentanyl