itruvone itruvone itruvone (inn; developmental code name ph10), also known as pregn-4-en-20-yn-3-one, is a vomeropherine which is under development by vistagen therapeutics as a nasal spray for the treatment of major depressive disorder. itruvoneclinical dataother namesph10; ph10a; ph10 ns; pregn-4-en-20-yn-3-oneroutes ofadministrationintranasal (spray)identifiers iupac name (8s,9s,10r,13s,14s,17r)-17-ethynyl-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopentaphenanthren-3-one cas number21321-89-1pubchem cid15633961chemspider18829396unii72hml2uk6jkeggd12542chemical and physical dataformulac21h28omolar mass296.454 g·mol−13d model (jsmol)interactive image smiles c12cc3(1cc2c#c)ccc4=cc(=o)cc34c inchi inchi=1s/c21h28o/c1-4-14-6-8-18-17-7-5-15-13-16(22)9-11-21(15,3)19(17)10-12-20(14,18)2/h1,13-14,17-19h,5-12h2,2-3h3/t14-,17-,18-,19-,20+,21-/m0/s1key:chouaxdnnavghr-nwsaayagsa-n