rowell's syndrome rowell's syndrome rowell's syndrome was described by professor neville rowell and colleagues in 1963. patients with the syndrome have lupus erythematosus (discoid or systemic), annular lesions of the skin like erythema multiforme associated with a characteristic pattern of immunological abnormalities. it is uncommon but occurs worldwide. rowell's syndrome has been reported to occur with all subtypes of le (systemic, acute, subacute or discoid).