mepiprazole mepiprazole mepiprazole (inn, ban) (brand name psigodal) is an anxiolytic drug of the phenylpiperazine group with additional antidepressant properties that is marketed in spain. it acts as a 5-ht2a and α1-adrenergic receptor antagonist and inhibits the reuptake and induces the release of serotonin, dopamine, and norepinephrine to varying extents, and has been described as a serotonin antagonist and reuptake inhibitor (sari). controlled clinical trials of mepiprazole in patients with irritable bowel syndrome (ibs) were also carried out and suggested some benefits of the drug in relieving symptoms of ibs in some patients. similarly to other phenylpiperazines like trazodone, nefazodone, and etoperidone, mepiprazole produces mcpp as an active metabolite. mepiprazoleclinical datatrade namespsigodalother namespap; emd-16923; h-4007routes ofadministrationoralatc codenonelegal statuslegal status in general: ℞ (prescription only) identifiers iupac name 1-(3-chlorophenyl)-4-piperazine cas number20326-12-9 20344-15-4 (hydrochloride)pubchem cid71897chemspider64909unii977bal0nr7comptox dashboard (epa)dtxsid30174223 chemical and physical dataformulac16h21cln4molar mass304.82 g·mol−13d model (jsmol)interactive image smiles cc3cc(ccn2ccn(c1cccc(cl)c1)cc2)n3