globotriaosylceramide: fabry's disease from sphingomyelin sphingomyelin: phospholipid: niemann–pick disease (smpd1-associated type c) glucocerebroside: gaucher's disease from sulfatide(sulfatidoses leukodystrophy) sulfatide: metachromatic leukodystrophy multiple sulfatase deficiency galactocerebroside: krabbe disease to sphingosine ceramide: farber disease ncl infantile jansky–bielschowsky disease batten disease other cerebrotendineous xanthomatosis cholesteryl ester storage disease (lysosomal acid lipase deficiency/wolman disease) sea-blue histiocytosis immunoproliferative immunoglobulin disorderspcds/pp plasmacytoma multiple myeloma (plasma cell leukemia) mgus igm (macroglobulinemia/waldenström macroglobulinemia) heavy chain (heavy chain disease) light chain (primary amyloidosis) other hypergammaglobulinemia cryoglobulinemia metal deficiency and toxicity disordersironexcess: iron overload hemochromatosis hemochromatosis/hfe1 juvenile/hfe2 hfe3 african iron overload/hfe4 aceruloplasminemia atransferrinemia hemosiderosis neurodegeneration with brain iron accumulation deficiency: iron deficiency copperexcess: copper toxicity wilson's disease deficiency: copper deficiency menkes disease/occipital horn syndrome zincexcess: zinc toxicity deficiency: acrodermatitis enteropathica other inborn errors of metabolism acid–base disordersacidosismetabolic high anion gap ketoacidosis diabetic ketoacidosis alcoholic ketoacidosis lactic normal anion gap hyperchloremic renal tubular respiratory respiratory alkalosis metabolic contraction alkalosis respiratory other mixed disorder of acid-base balance acid–base homeostasis inborn error of purine–pyrimidine metabolismpurine metabolismanabolism adenylosuccinate lyase deficiency adenosine monophosphate deaminase deficiency type 1 nucleotide salvage lesch–nyhan syndrome/hyperuricemia adenine phosphoribosyltransferase deficiency catabolism adenosine deaminase deficiency purine nucleoside phosphorylase deficiency xanthinuria gout mitochondrial neurogastrointestinal encephalopathy syndrome pyrimidine metabolismanabolism orotic aciduria miller syndrome catabolism dihydropyrimidine dehydrogenase deficiency heme metabolism disordersporphyria,hepatic and erythropoietic(porphyrin)early mitochondrial: alad porphyria acute intermittent porphyria cytoplasmic: gunther disease/congenital erythropoietic porphyria porphyria cutanea tarda/hepatoerythropoietic porphyria late mitochondrial: hereditary coproporphyria harderoporphyria variegate porphyria erythropoietic protoporphyria hereditary hyperbilirubinemia(bilirubin)unconjugated: gilbert's syndrome crigler–najjar syndrome lucey–driscoll syndrome conjugated: dubin–johnson syndrome rotor syndrome amyloidosiscommon amyloid forming proteins aa attr aβ2m al aβ/app aiapp acal apro aanf acys abri systemic amyloidosis al amyloidosis aa amyloidosis aβ2m/haemodialysis-associated agel/finnish type aa/familial mediterranean fever attr/transthyretin-related hereditary organ-limited amyloidosisheartaanf/isolated atrialbrain familial amyloid neuropathy acys+abri/cerebral amyloid angiopathy aβ/alzheimer's disease kidney aapoa1+afib+alys/familial renal skin primary cutaneous amyloidosis amyloid purpura endocrine thyroid acal/medullary thyroid cancer pituitary apro/prolactinoma pancreas aiapp/insulinoma type 2 diabetes lysosomal storage diseases: inborn errors of carbohydrate metabolism (mucopolysaccharidoses)catabolism mps i hurler syndrome, hurler–scheie syndrome, scheie syndrome mps ii: hunter syndrome mps iii: sanfilippo syndrome mps iv: morquio syndrome mps vi: maroteaux-lamy syndrome mps vii: sly syndrome mps ix: hyaluronidase deficiency inborn error of lipid metabolism: fatty-acid metabolism disorderssynthesis biotinidase deficiency (btd) degradationacyltransport carnitine cpt1 cpt2 cdsp cactd adrenoleukodystrophy (ald) betaoxidationgeneral acyl coa dehydrogenase short-chain scadd medium-chain mcadd long-chain 3-hydroxy lchad very long-chain vlcadd mitochondrial trifunctional protein deficiency (mtpd): acute fatty liver of pregnancy unsaturated 2,4 dienoyl-coa reductase deficiency (decrd) odd chain propionic acidemia (pcc deficiency) other 3-hydroxyacyl-coenzyme a dehydrogenase deficiency (hadhd) glutaric acidemia type 2 (madd) toacetyl-coa malonic aciduria (mcd) aldehyde sjögren–larsson syndrome (sls) genetic disorder, organelle: peroxisomal disorders and lysosomal structural disordersperoxisome biogenesis disorder zellweger syndrome neonatal adrenoleukodystrophy infantile refsum disease adult refsum disease-2 rcp 1 enzyme-related acatalasia rcp 2&3 mevalonate kinase deficiency d-bifunctional protein deficiency adult refsum disease-1 transporter-related x-linked adrenoleukodystrophy lysosomal danon disease