ms-245 ms-245 ms-245 is a tryptamine derivative used in scientific research. it acts as a selective 5-ht6 receptor antagonist with a ki of 2.3 nm, and was derived through structure-activity relationship development of the selective 5-ht6 agonist emdt. it has been used as a lead compound for further development of tryptamine-derived 5-ht6 antagonists. in animal studies it has been shown to boost the activity of, but not substitute for, both amphetamine and nicotine. ms-245clinical dataatc codenoneidentifiers iupac name 2--n,n-dimethylethanamine cas number263384-65-2 ypubchem cid6918542chemspider5293739uniil7tkh887y7chemical and physical dataformulac19h22n2o3smolar mass358.46 g·mol−13d model (jsmol)interactive image smiles coc2cc1c(ccn(c)c)cn(c1cc2)s(=o)(=o)c3ccccc3 inchi inchi=1s/c19h22n2o3s/c1-20(2)12-11-15-14-21(19-10-9-16(24-3)13-18(15)19)25(22,23)17-7-5-4-6-8-17/h4-10,13-14h,11-12h2,1-3h3key:aijiqcbymbzljd-uhfffaoysa-n (verify)