research program at brigham and women’s hospital, broad institute and harvard medical school was established in 2012 to conduct empirical research in translating genomics into health. brigham and women's hospital opened a preventive genomics clinic in august 2019, with massachusetts general hospital following a month later. the all of us research program aims to collect genome sequence data from 1 million participants to become a critical component of the precision medicine research platform. synthetic biology and bioengineering the growth of genomic knowledge has enabled increasingly sophisticated applications of synthetic biology. in 2010 researchers at the j. craig venter institute announced the creation of a partially synthetic species of bacterium, mycoplasma laboratorium, derived from the genome of mycoplasma genitalium. population and conservation genomics population genomics has developed as a popular field of research, where genomic sequencing methods are used to conduct large-scale comparisons of dna sequences among populations - beyond the limits of genetic markers such as short-range pcr products or microsatellites traditionally used in population genetics. population genomics studies genome-wide effects to improve our understanding of microevolution so that we may learn the phylogenetic history and demography of a population. population genomic methods are used for many different fields including evolutionary biology, ecology, biogeography, conservation biology and fisheries management. similarly, landscape genomics has developed from landscape genetics to use genomic methods to identify relationships between patterns of environmental and genetic variation. conservationists can use the information gathered by genomic sequencing in order to better evaluate genetic factors key to species conservation, such as the genetic diversity of a population or whether an individual is heterozygous for a recessive inherited genetic disorder. by using genomic data to evaluate the effects of evolutionary processes and to detect patterns in variation throughout a given population, conservationists can formulate plans to aid a given species without as many variables left unknown as those unaddressed by standard genetic approaches.