lactucopicrin lactucopicrin lactucopicrin (intybin) is a bitter substance that has a sedative and analgesic effect, acting on the central nervous system. it is a sesquiterpene lactone, and is a component of lactucarium, derived from the plant lactuca virosa (wild lettuce), as well as being found in some related plants such as cichorium intybus. it is also found in dandelion coffee. lactucopicrin names preferred iupac name furan-9-yl]methyl (4-hydroxyphenyl)acetate other names intybin identifiers cas number 6466-74-6 (3ar,4s,9bs) 3d model (jsmol) interactive image chemspider 152483 (3ar,4s,9bs) mesh intybin pubchem cid 174863 (3ar,4s,9bs) unii skg846kj3g y comptox dashboard (epa) dtxsid90983277 inchi inchi=1s/c23h22o7/c1-11-7-16(25)20-12(2)23(28)30-22(20)21-14(9-17(26)19(11)21)10-29-18(27)8-13-3-5-15(24)6-4-13/h3-6,9,16,20-22,24-25h,2,7-8,10h2,1h3/t16-,20+,21-,22-/m0/s1key: qcdlliutdgncpo-aemjnjessa-ninchi=1/c23h22o7/c1-11-7-16(25)20-12(2)23(28)30-22(20)21-14(9-17(26)19(11)21)10-29-18(27)8-13-3-5-15(24)6-4-13/h3-6,9,16,20-22,24-25h,2,7-8,10h2,1h3/t16-,20+,21-,22-/m0/s1key: qcdlliutdgncpo-aemjnjesbm smiles cc1=c2(3((c1)o)c(=c)c(=o)o3)c(=cc2=o)coc(=o)cc4ccc(cc4)o properties chemical formula c23h22o7 molar mass 410.422 g·mol−1 pharmacology routes ofadministration oral, smoked except where otherwise noted, data are given for materials in their standard state (at 25 °c , 100 kpa). infobox references as well as their traditional use as sedatives and analgesics, these plants have also been used as antimalarials, and both lactucin and lactucopicrin have demonstrated antimalarial effects in vitro. lactucopicrin has also been shown to act as an acetylcholinesterase inhibitor.