testosterone undecanoate testosterone undecanoate testosterone undecanoate, sold under the brand names andriol and aveed among others, is an androgen and anabolic steroid (aas) medication that is used mainly in the treatment of low testosterone levels in men, it is taken by mouth or given by injection into muscle. testosterone undecanoateclinical datapronunciation/tɛˈstɒstəroʊn ənˈdɛkənoʊeɪt/ teh-stos-tə-rohn ən-dek-ə-noh-ayt trade namesoral: andriol, jatenzo, othersim: aveed, nebido, othersother namestu; testosterone undecylate; testosterone 17β-undecanoate; org-538; clr-610ahfs/drugs.commonographmedlineplusa614041license data us dailymed: testosterone_undecanoate pregnancycategory au: d routes ofadministrationby mouth, intramuscular injectiondrug classandrogen; anabolic steroid; androgen esteratc codeg03ba03 (who) legal statuslegal status ca: schedule iv us: schedule iii pharmacokinetic databioavailabilityoral: 3–7%intramuscular: highprotein bindinghigh (testosterone)metabolismlivermetabolitestestosterone, undecanoic acid, metabolites of testosteroneelimination half-lifeim (in tea seed oil): 20.9 daysim (in castor oil): 33.9 daysexcretion~90% urine, 6% fecesidentifiers iupac name phenanthren-17-yl] undecanoate cas number5949-44-0 ypubchem cid65157drugbankdb13946 ychemspider58664 yuniih16a5vct9ckeggd06087 ychebichebi:135741 ychemblchembl2107067 yecha infocard100.025.193 chemical and physical dataformulac30h48o3molar mass456.711 g·mol−13d model (jsmol)interactive image smiles ccccccccccc(=o)o1cc21(cc32ccc4=cc(=o)cc34c)c inchi inchi=1s/c30h48o3/c1-4-5-6-7-8-9-10-11-12-28(32)33-27-16-15-25-24-14-13-22-21-23(31)17-19-29(22,2)26(24)18-20-30(25,27)3/h21,24-27h,4-20h2,1-3h3/t24-,25-,26-,27-,29-,30-/m0/s1 nkey:udsfvoauhkgbek-cnqksjkfsa-n n (verify) side effects of testosterone undecanoate include symptoms of masculinization like acne, increased hair growth, voice changes, hypertension, elevated liver enzymes, hypertriglyceridemia, and increased sexual desire. the drug is a prodrug of testosterone, the biological ligand of the androgen receptor (ar) and hence is an androgen and anabolic steroid. it has strong androgenic effects and moderate anabolic effects, which make it useful for producing masculinization and suitable for androgen replacement therapy. testosterone undecanoate is a testosterone ester and a prodrug of testosterone in the body. because of this, it is considered to be a natural and bioidentical form of testosterone. testosterone undecanoate was introduced in china for use by injection and in the european union for use by mouth in the 1970s. it became available for use by injection in the european union in the early to mid 2000s and in the united states in 2014. formulations for use by mouth are approved in the united states. along with testosterone enanthate, testosterone cypionate, and testosterone propionate, testosterone undecanoate is one of the most widely used testosterone esters. however, it has advantages over other testosterone esters in that it can be taken by mouth and in that it has a far longer duration when given by injection. in addition to its medical use, testosterone undecanoate is used to improve physique and performance. the drug is a controlled substance in many countries and so non-medical use is generally illicit. oral administration of testosterone undecanoate is an effective method to achieve therapeutic physiological levels of serum testosterone in patients with hypogonadism. in addition, oral therapy has been found to have a positive impact on quality of life factors such as sexual function, mood, and mental status, as documented in various studies. medical dosage