hepatitis x hepatitis x non-a-e hepatitis, also known as hepatitis x, is an infectious disease of the liver referring to a case of viral hepatitis that cannot be attributed to hepatitis a, b, c, d, or e. the disease involves swelling and inflammation of the liver. symptoms of non-a-e hepatitis may include tiredness, nausea, vomiting, abdomen pain, and a fever. the specific cause of non-a-e hepatitis is unknown. it is considered a rare disorder. hepatitis xspecialtyhepatology