giardiavirus giardiavirus giardiavirus is a genus of viruses, in the family totiviridae. protozoa serve as natural hosts. there is only one species in this genus: giardia lamblia virus. giardia lamblia virus cryo-em reconstruction of giardia lamblia virus (glv) particle color based on distance from center virus classification (unranked): virus realm: riboviria kingdom: orthornavirae phylum: duplornaviricota class: chrymotiviricetes order: ghabrivirales family: totiviridae genus: giardiavirus species: giardia lamblia virus structure viruses in giardiavirus are non-enveloped, with icosahedral geometries, and t=2 symmetry. the diameter is around 36 nm. genomes are linear, around 6277kb in length. the genome has 2 open reading frames. genusstructuresymmetrycapsidgenomic arrangementgenomic segmentation giardiavirusicosahedralt=2non-envelopedlinearmonopartite life cycle viral replication is cytoplasmic. entry into the host cell is achieved by attachment to host receptors, which mediates endocytosis. replication follows the double-stranded rna virus replication model. double-stranded rna virus transcription is the method of transcription. translation takes place by -1 ribosomal frameshifting, and viral initiation. protozoa serve as the natural host. genushost detailstissue tropismentry detailsrelease detailsreplication siteassembly sitetransmission giardiavirusprotozoanonecell receptor endocytosisexocytosiscytoplasmcytoplasmpassive diffusion taxonomy the genus giardiavirus has one species: giardia lamblia virus