tuberomammillary nucleus tuberomammillary nucleus the tuberomammillary nucleus (tmn) is a histaminergic nucleus located within the posterior third of the hypothalamus. it consists of, largely, histaminergic neurons (i.e., histamine-releasing neurons) and is involved with the control of arousal, learning, memory, sleep and energy balance. tuberomammillary nucleustuberomammillary nucleus of the mouse braindetailspart ofhypothalamusidentifierslatinnucleus tuberomamillarisacronym(s)tmnneuronames427neurolex idbirnlex_1271ta98a14.1.08.932ta25734fma62335anatomical terms of neuroanatomy histaminergic outputs