romifidine romifidine romifidine is a drug that is used in veterinary medicine as a sedative mainly in large animals such as horses, although it may be used in a wide variety of species. it is not used in humans, but is closely related in structure to the commonly used drug clonidine. romifidineclinical dataahfs/drugs.cominternational drug namesroutes ofadministrationivatcvet codeqn05cm93 (who) legal statuslegal status veterinary use only identifiers iupac name n-(2-bromo-6-fluorophenyl)-4,5-dihydro-1h-imidazol-2-amine cas number65896-16-4 ypubchem cid71969chemspider64975 nunii876351l05kcomptox dashboard (epa)dtxsid40216103 echa infocard100.158.065 chemical and physical dataformulac9h9brfn3molar mass258.09 g·mol−13d model (jsmol)interactive image smiles c1cn=c(n1)nc2=c(c=cc=c2br)f inchi inchi=1s/c9h9brfn3/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9/h1-3h,4-5h2,(h2,12,13,14) nkey:kdpnlrqzhdjrfu-uhfffaoysa-n n ny (what is this?) (verify) romifidine acts as an agonist at the α2 adrenergic receptor subtype. side effects can include bradycardia and respiratory depression. it is often used alongside other sedative or analgesic drugs such as ketamine or butorphanol. yohimbine can be used as an antidote to rapidly reverse the effects.