comes to an end. the auto-phagosome combines with the lysosomal vesicles to formulate an auto-lysosome that degrades the encapsulated substances, referred to as phagocytosis. notable cell biologists jean baptiste carnoy peter agre günter blobel robert brown geoffrey m. cooper christian de duve henri dutrochet robert hooke h. robert horvitz marc kirschner anton van leeuwenhoek ira mellman peter d. mitchell rudolf virchow paul nurse george emil palade keith r. porter ray rappaport michael swann roger tsien edmund beecher wilson kenneth r. miller matthias jakob schleiden theodor schwann yoshinori ohsumi jan evangelista purkyně czech anatomist jan evangelista purkyně is best known for his 1837 discovery of purkinje cells. theodor schwann, discoverer of the schwann cell yoshinori ohsumi, nobel prize winner for work on autophagy