linsidomine linsidomine linsidomine (3-morpholinosydnonimine or sin-1) is a vasodilator. it is a metabolite of the antianginal drug molsidomine and acts by releasing no from the endothelial cells nonenzymatically. it also hyperpolarizes the cell membrane through influencing the sodium-potassium pump and thereby rendering it less responsive to adrenergic stimulation. linsidomine injection at a dose of 1 mg produces usable erection in about 70% of patients and full erection in up to 50% of patients. linsidomine does not appear to be associated with priapism. linsidomineclinical dataother namessin-1ahfs/drugs.cominternational drug namesatc codec01dx18 (who) identifiers iupac name 5-imino-3-morpholin-4-yl-5h-1,2,3-oxadiazol-3-ium-2-ide cas number33876-97-0 y 16142-27-1 (hydrochloride)pubchem cid5219chemspider10561427unii5o5u71p6vqkeggd07161 ychemical and physical dataformulac6h10n4o2molar mass170.172 g·mol−13d model (jsmol)interactive image smiles c1coccn12=noc(=c2) inchi inchi=1s/c6h10n4o2/c7-6-5-10(8-12-6)9-1-3-11-4-2-9/h5,7h,1-4h2key:fkdhhvkwgrfrtg-uhfffaoysa-n (verify) linsidomine is neurotoxic and promotes oxidative stress on neurons. linsidomine is a peroxynitrite-generating compound involved in the pathogenesis of neurodegenerative diseases.