vldlr-associated cerebellar hypoplasia vldlr-associated cerebellar hypoplasia vldlr-associated cerebellar hypoplasia (vldlrch) is a rare autosomal recessive condition caused by a disruption of the vldlr gene. first described as a form of cerebral palsy in the 1970s, it is associated with parental consanguinity and is found in secluded communities, with a number of cases described in hutterite families. vldlr-associated cerebellar hypoplasiaother namesdysequilibrium syndrome, des; nonprogressive cerebellar disorder with mental retardation)