1-methyl-3-propyl-4-(p-chlorophenyl)piperidine 1-methyl-3-propyl-4-(p-chlorophenyl)piperidine 1-methyl-3-propyl-4-(p-chlorophenyl)piperidine is a drug developed by a team led by alan kozikowski, which acts as a potent dopamine reuptake inhibitor, and was developed as a potential therapeutic agent for the treatment of cocaine addiction. as with related compounds such as nocaine, it is a structurally simplified derivative of related phenyltropane compounds. its activity at the serotonin and noradrenaline transporters has not been published, though most related 4-phenylpiperidine derivatives are relatively selective for inhibiting dopamine reuptake over the other monoamine neurotransmitters. while several of its isomers are active, the (3s,4s)-enantiomer is by far the most potent. the rearranged structural isomer 2-piperidine is also a potent inhibitor of dopamine reuptake. 2-piperidine 1-methyl-3-propyl-4-(p-chlorophenyl)piperidineidentifiers iupac name (3s,4s)-4-(4-chloro-phenyl)-1-methyl-3-propyl-piperidine cas number214335-23-6 (3s,4s enantiomer) 1956381-81-9 (racemate)pubchem cid9837874chemspider8013594chemblchembl109097chemical and physical dataformulac15h22clnmolar mass251.80 g·mol−13d model (jsmol)interactive image smiles ccc1cn(cc1c2=cc=c(c=c2)cl)c inchi inchi=1s/c15h22cln/c1-3-4-13-11-17(2)10-9-15(13)12-5-7-14(16)8-6-12/h5-8,13,15h,3-4,9-11h2,1-2h3/t13-,15-/m1/s1key:mwgrxfwgmdsmni-ukrrqhhqsa-n