diphenylbutylpiperidine diphenylbutylpiperidine diphenylbutylpiperidines are a class of typical antipsychotic drugs which were all synthesized, developed, and marketed by janssen pharmaceutica. base chemical structure of the diphenylbutylpiperidine antipsychotics. they include: clopimozide (r-29,764) fluspirilene (redeptin) penfluridol (semap, micefal, longoperidol) pimozide (orap)