bromisoval bromisoval bromisoval (inn), commonly known as bromovalerylurea, is a hypnotic and sedative of the bromoureide group discovered by knoll in 1907 and patented in 1909. it is marketed over the counter in asia under various trade names (such as brovarin), usually in combination with nonsteroidal anti-inflammatory drugs. bromisoval names iupac name (rs)-2-bromo-n-carbamoyl-3-methylbutanamide identifiers cas number 496-67-3 y27109-49-5 r y27109-48-4 s y 3d model (jsmol) interactive image chebi chebi:31304 chembl chembl1515611 y chemspider 2353 y129594 r y643139 s y echa infocard 100.007.115 ec number 207-825-7 kegg d01391 mesh bromisovalum pubchem cid 2447146955 r735997 s unii 469gw8r486 y3dy4yga2px r ygtj4y0jw4d s y comptox dashboard (epa) dtxsid2040656 inchi inchi=1s/c6h11brn2o2/c1-3(2)4(7)5(10)9-6(8)11/h3-4h,1-2h3,(h3,8,9,10,11) ykey: cmcchhwttbeznm-uhfffaoysa-n y smiles cc(c)c(br)c(=o)nc(n)=o properties chemical formula c6h11brn2o2 molar mass 223.070 g·mol−1 log p 1.057 acidity (pka) 10.536 basicity (pkb) 3.461 pharmacology atc code n05cm03 (who) routes ofadministration oral related compounds related ureas carbromal related compounds 3-ureidopropionic acidbeta-ureidoisobutyric acidcarbamoyl aspartic acidn-acetylaspartic acidaceglutamiden-acetylglutamic acidcitrulline except where otherwise noted, data are given for materials in their standard state (at 25 °c , 100 kpa). infobox references chronic use of bromisoval has been associated with bromine poisoning. bromisoval can be prepared by bromination of isovaleric acid by the hell-volhard-zelinsky reaction followed by reaction with urea.