hesperadin hesperadin hesperadin is an aurora kinase inhibitor. hesperadin names preferred iupac name n-anilino}methylidene)-2,3-dihydro-1h-indol-5-yl]ethanesulfonamide identifiers cas number 422513-13-1 y 3d model (jsmol) interactive image chemspider 8318096 n pubchem cid 10142586 unii ptr491os14 y comptox dashboard (epa) dtxsid00195086 inchi inchi=1s/c29h32n4o3s/c1-2-37(35,36)32-24-15-16-26-25(19-24)27(29(34)31-26)28(22-9-5-3-6-10-22)30-23-13-11-21(12-14-23)20-33-17-7-4-8-18-33/h3,5-6,9-16,19,30,32h,2,4,7-8,17-18,20h2,1h3,(h,31,34)/b28-27- nkey: gldskrngvvyjab-dqsjhhfosa-n ninchi=1/c29h32n4o3s/c1-2-37(35,36)32-24-15-16-26-25(19-24)27(29(34)31-26)28(22-9-5-3-6-10-22)30-23-13-11-21(12-14-23)20-33-17-7-4-8-18-33/h3,5-6,9-16,19,30,32h,2,4,7-8,17-18,20h2,1h3,(h,31,34)/b28-27-key: gldskrngvvyjab-dqsjhhfobf smiles ccs(=o)(=o)nc1=cc2=c(c=c1)nc(=o)c2=c(c3=cc=cc=c3)nc4=cc=c(c=c4)cn5ccccc5 properties chemical formula c29h32n4o3s molar mass 516.66 g·mol−1 except where otherwise noted, data are given for materials in their standard state (at 25 °c , 100 kpa). n verify (what is yn ?) infobox references the small molecule inhibits chromosome alignment and segregation by limiting the function of mitotic kinases aurora b and aurora a. hesperadin causes cells to enter anaphase much faster, sometimes before the chromosomes are properly bi-oriented. hesperadin, like other miotic inhibitors, limits and sometimes can stop the process of mitosis in cells. for this reason, some have considered hesperadin's potential as a cancer-preventing drug. hesperadin works as an inhibitor, attaching to the active sites of aurora a and aurora b kinases.