nedocromil nedocromil nedocromil sodium is a medication considered as mast cell stabilizer which acts to prevent wheezing, shortness of breath, and other breathing problems caused by asthma. it is administered by an inhaler under the brand name tilade, and as an eye drop under the brand name alocril. the effects of nedocromil versus asthma are gradual rather than fast-acting and it is not indicated for acute respiratory distress compared to fast acting bronchodilators like albuterol or other well-known inhaler medications. liquid preparations of nedocromil are available in the uk under the name rapitil for use for allergic eye reactions. nedocromil sodium has been shown to be effective in alleviating symptoms of allergic conjunctivitis. nedocromilclinical datatrade namesalocrilahfs/drugs.commonographmedlineplusa601243routes ofadministrationinhalation and eye dropsatc coder01ac07 (who) r03bc03 (who), s01gx04 (who)legal statuslegal status au: s4 (prescription only) uk: pom (prescription only) us: ℞-only pharmacokinetic dataprotein binding89%metabolismnot metabolizedelimination half-life~3.3 hoursexcretionexcreted unchangedidentifiers iupac name 9-ethyl-4,6-dioxo-10-propyl-6,9-dihydro-4h-pyranoquinoline-2,8-dicarboxylic acid cas number69049-73-6 ypubchem cid50294iuphar/bps7607drugbankdb00716 ychemspider45608 yunii0b535e0bn0keggd05129 ychebichebi:7492 ychemblchembl746 ycomptox dashboard (epa)dtxsid7023356 echa infocard100.233.208 chemical and physical dataformulac19h17no7molar mass371.345 g·mol−13d model (jsmol)interactive image smiles o=c\1c3c(n(/c(c(=o)o)=c/1)cc)c(c2o/c(=c\c(=o)c2c3)c(=o)o)ccc inchi inchi=1s/c19h17no7/c1-3-5-9-16-10(13(21)7-12(18(23)24)20(16)4-2)6-11-14(22)8-15(19(25)26)27-17(9)11/h6-8h,3-5h2,1-2h3,(h,23,24)(h,25,26) ykey:rqtoofixokygan-uhfffaoysa-n y (verify) nedocromil is classified as a benzopyrone. nedocromil acts as a mast cell stabilizer, inhibits the degranulation of mast cells, prevents release of histamine and tryptase, so preventing the synthesis of prostaglandins and leukotrienes. us production of inhaled nedocromil ceased in april 2008 because it used cfcs as propellant.