pulpotomy pulpotomy pulpotomy is a minimally invasive procedure performed in children on a primary tooth with extensive caries but without evidence of root pathology. the minimally invasive endodontic techniques of vital pulp therapy (vpt) are based on improved understanding of the capacity of pulp (nerve) tissues to heal and regenerate plus the availability of advanced endodontic materials. during the caries removal, this results in a carious or mechanical pulp exposure (bleeding) from the cavity. during pulpotomy, the inflamed/diseased pulp tissue is removed from the coronal pulp chamber of the tooth leaving healthy pulp tissue which is dressed with a long-term clinically-successful medicament that maintains the survival of the pulp and promotes repair. there are various types of medicament placed above the vital pulp such as buckley's solution of formocresol, ferric sulfate, calcium hydroxide or mineral trioxide aggregate (mta). mta is a more recent material used for pulpotomies with a high rate of success, better than formocresol or ferric sulfate. it is also recommended to be the preferred pulpotomy agent in the future. after the coronal pulp chamber is filled, the tooth is restored with a filling material that seals the tooth from microleakage, such as a stainless steel crown which is the most effective long-term restoration. however, if there is sufficient remaining supporting tooth structure, other filling materials such as amalgam or composite resin can provide a functional alternative when the primary tooth has a life span of two years or less. the medium- to long-term treatment outcomes of pulpotomy in symptomatic permanent teeth with caries, especially in young people, indicate that pulpotomy can be a potential alternative to root canal therapy (rct). diagram of pulpotomy visual of tooth decay there is another term, which is also related to vital pulp therapy, which is apexogenesis. apexogenesis is a treatment in preserving vital pulp tissue in the apical part of a root canal to allow the completion in formation of the root apex. this clinical procedure is essentially a deep pulpotomy, aimed to preserve the pulp in immature teeth that have deep pulpal inflammation. examples include teeth with carious exposures and trauma in which treatment of the exposed pulp is delayed and it becomes necessary to extend farther into the canal to reach healthy tissue. objectives in primary tooth after the pulpotomy treatment, the radicular pulp should remain asymptomatic without any adverse clinical signs or symptoms such as sensitivity, pain, or swelling. from the radiographs, there should be absence of postoperative evidence of pathologic root resorption. there should be absence of clinical signs of infection and inflammation and no harm to the succedaneous tooth. however, radiographs play a very important role, to check if pulpotomy can be done on the primary tooth. for example, the aspects we considered are the extension of caries in the primary tooth, and the development of the succedaneous permanent tooth. the radiograph shows a primary tooth with succedaneous permanent teeth. radiographs are needed to determine if pulpotomy can be carried out. in mature permanent tooth the tooth should be asymptomatic. there should be no clinical signs and symptoms. from the radiographs, there should be absence of postoperative evidence of pathology. in immature tooth pulpotomy allows the continuation of root formation, leading to tooth end closure, preservation and maintenance of pulp vitality, stronger root structure and greater structural integrity. indications primary teeth primary/deciduous (baby) teeth in children have relatively large pulp spaces. caries do not have to develop significantly before they reach the pulp chamber. when the soft tissue in the pulp chamber is infected (has bacteria in it) or affected (is inflamed), it can be removed by a dentist or dental therapist under local anaesthetic. if the soft tissue in the canals is still healthy enough, a special medicated filling can be put into the chamber in an attempt to keep the remaining pulp (in the canals) alive. the process of removing the pulp from the chamber is the actual "pulpotomy", though the word is often used for the entire process including placement of the medication. there are many medicaments that can be used to fill the pulp chamber including zinc-oxide eugenol as well as mineral trioxide aggregate. there are two types of pulpotomy techniques depending the extent of caries in a tooth and the symptoms it presents. a vital pulpotomy or a non-vital pulpotomy can be carried out. however, recent research shows that non-vital pulpotomies are rarely indicated due to their low success rates and it is therefore sometimes better to extract the tooth. afterwards the tooth is restored with a regular filling, either composite or amalgam, or a stainless steel crown. due to the process of a pulpotomy causing the tooth to become slightly brittle, a stainless steel crown is normally indicated as the preferred choice of definitive restoration. a pulpotomy can be done to both permanent and primary teeth. types primary teeth the indication of this pulpotomy procedure is when pulp exposure occurs during caries removal in a primary tooth with a normal pulp or reversible pulpitis or after a traumatic pulp exposure. then, the coronal tissue is amputated, and the remaining radicular tissue is judged to be vital without suppuration, pus, necrosis, or excessive bleeding which cannot be controlled by a moist cotton pellet (with saline) after several minutes, and there are no radiographic signs of infection or pathologic resorption. pulpotomy therapy can be classified according to the following treatment objectives: devitalization (mummification, cauterization), preservation (minimal devitalization, noninductive), or regeneration (inductive, reparative). devitalization multiple visits with application of formocresol in pulpotomy is used to fix the radicular pulp completely to reduce pulp infection. the radicular pulp was theoretically sterilized and devitalized, thereby reducing infection and internal resorption. another form of nonchemical devitalization emerged: electrosurgical pulpotomy. electrocautery releases heat that denatures pulp and reduces bacterial contamination. experimentally, electrosurgery has been shown to reduce pathologic root resorption and periapical pathology, and a series of pulpal effects including acute and chronic inflammation, swelling and diffuse necrosis. it is reported that this method has high success rate in pulpotomies. however, this method may prove to be more diagnosis and technique sensitive, and it may not be suitable if apical root resorption has occurred. preservation zinc oxide-eugenol (zoe) was the first agent to be used for preservation. in recent years, glutaraldehyde has been proposed as an alternative to formocresol based on: its superior fixative properties, and low toxicity. a nonaldehyde chemical, ferric sulfate, has received some attention recently as a pulpotomy agent. it minimizes the chances for inflammation and internal resorption. this category of pulp therapy is still in flux, although major changes in the future are not likely. regeneration the ideal pulpotomy treatment should leave the radicular pulp alive and healthy in this case, the tooth should be filled with noxious restorative materials within, thereby diminishing the chances of internal resorption, as well as formation of reparative dentin. calcium hydroxide was the first agent used in pulpotomies that demonstrated any capacity to induce regeneration of dentin. however, the success rate is not that high. recent advances in the field of bone and dentin formation have opened exciting new vistas for pulp therapy, which is a factor called bone morphogenetic protein (bmp). it has bone inductive properties, that can predictably induce bone for use in the fields of orthopedic, oral, and periodontal surgery. most importantly for dentistry, these osteogenic proteins hold promise for pulp therapy. partial pulpotomy for carious exposures partial pulpotomy is also indicated in young permanent teeth with pulp exposure due to caries, provided that the bleeding can be controlled within several minutes. it is a procedure in which the inflamed pulp tissue beneath an exposure is removed to a depth of 1 to 3mm or deeper to reach the level of healthy pulp tissue. pulpal bleeding can be controlled by irrigation of sodium hypochlorite or chlorhexidine. the site is then covered with a pulpal medicament, calcium hydroxide or mta, followed by a final restoration that provides a complete seal to prevent any leakage and bacterial contamination following the restoration. after the procedure, the remaining pulp should remain vital and the patient should be free of any adverse clinical signs or symptoms such as sensitivity, pain or swelling. immature teeth should continue its normal development and apexogenesis. partial pulpotomy for traumatic exposures tooth crown fractures are one of the most common dental injuries and the pulp is exposed in approximately 25% of all crown fractures. maintaining vitality of the pulp tissue in an immature tooth is important to allow continued growth of the tooth. partial pulpotomy due to a traumatic exposure is also known as cvek pulpotomy. the procedure involves removal of 1 to 3 mm (0.04 to 0.1 in) of inflamed pulp tissue beneath an exposure to reach the level of healthy pulp tissue. the surface of the remaining pulp is then irrigated with bacteriocidal irrigants such as sodium hypochlorite or chlorhexidine until bleeding has ceased. the site is then covered with a pulpal medicament, either calcium hydroxide or mta. the remaining cavity is then restored with a material that provides a complete seal to prevent any leakage and bacterial contamination following the restoration. the remaining pulp tissue should continue to be vital after partial pulpotomy and teeth with immature roots should show continued normal development and apexogenesis. there should be no signs of pain, swelling, or sensitivity after the procedure. cvek at al reported that partial pulpotomies after a traumatic exposure had a success rate of 96%. medicaments pulpotomy is a vital pulp therapy, medicaments that can promote healing and preserve the vitality of the tooth should be placed after removal of the inflamed pulp. in primary teeth medicaments such as formocresol, mineral trioxide aggregate, zinc oxide eugenol and calcium hydroxide can be used in pulpotomy. formocresol use has been questioned due to toxicity concerns. ferric sulfate, sodium hypochlorite or a local anaesthetic solution containing a vasoconstrictor agent can be used to arrest any bleeding from the pulp prior to the placement of medicament. calcium enriched mixtures have been used in permanent molar teeth with irreversible pulpitis showing positive outcomes. ferric sulfate ferric sulfate is used to arrest pulpal bleeding by forming a sealing membrane through the agglutination of the blood proteins with ferric and sulfate ions. this metal-protein clot at the surface of the pulp may act as a barrier to external irritants. the physiological clot formation is thought to be able to minimize inflammation and internal resorption compared to calcium hydroxide. most importantly, ferric sulfate causes minimal devitalization and subsequent preservation of the pulp tissue. ferric sulphate has been shown to have close to a 100% clinical success compared to formocresol (77%) with one-year follow-up. formocresol formocresol has been used in pulpotomy procedures of the primary teeth since 80 years. formocresol is both a bactericidal and devitalizing agent. it kills bacteria and converts the pulp tissue into inert compounds. this action fastens the vital pulp, maintaining them inert and conserves the primary tooth until it falls off physiologically. however, formaldehyde, a primary component in formocresol has raised concerns regarding its safe of use. formaldehyde is a hazardous substance and has perceived the need to reevaluate the use of formocresol. zinc oxide-eugenol (zoe) after pulpal bleeding is arrested, a suitable base such as zinc oxide-eugenol is placed to seal the tooth from microleakage. zoe is a nontoxic material for pulpal cells and possess antimicrobial as well as anti-inflammatory properties. in addition, it also has local anesthetic or soothing effect on the dental pulp. calcium hydroxide calcium hydroxide ca(oh)2 is conventionally used as a pulpotomy agent of the permanent teeth but with less long term success. calcium hydroxide is a highly alkaline (ph 12) material that has bactericidal effect and has the potential to enhance reparative dentin (dentin bridge) formation. however, it also leads to superficial necrosis of the pulp tissue in contact with the medication and has been shown to be toxic to cells in tissue culture. therefore, in spite being a popular vital pulp therapy material, its use as a pulpotomy agent remains controversial. mineral trioxide aggregate (mta) mta is a more recent material that consists of tricalcium silicate, dicalcium silicate, tricalcium aluminate, tetracalcium aluminoferrite, bismuth oxide and calcium sulfate. mta is known to have excellent physical characteristics, biocompatibility and has the ability to stimulate cytokine release from pulpal