ro48-8684 ro48-8684 ro48-8684 is a water-soluble benzodiazepine derivative developed by hoffman-laroche in the 1990s, which was designed along with ro48-6791 as an improved replacement for midazolam, but ultimately proved to have little advantages over the parent drug and has not been introduced into clinical practice. ro48-8684identifiers iupac name 3-(5-dipropylaminomethyloxazol-2-yl)-8-fluoro-5-methyl-5,6-dihydro-4h-imidazobenzodiazepin-6-one pubchem cid9866317chemspider8042008chemical and physical dataformulac22h26fn5o2molar mass411.472 g·mol−13d model (jsmol)interactive image smiles cccn(cc1=cn=c(c2=c(cn(c(c3=c4c=cc(f)=c3)=o)c)n4c=n2)o1)ccc inchi inchi=1s/c22h26fn5o2/c1-4-8-27(9-5-2)12-16-11-24-21(30-16)20-19-13-26(3)22(29)17-10-15(23)6-7-18(17)28(19)14-25-20/h6-7,10-11,14h,4-5,8-9,12-13h2,1-3h3key:ykklhehnuyclqq-uhfffaoysa-n (verify)