tracazolate tracazolate tracazolate (ici-136,753) is an anxiolytic drug which is used in scientific research. it is a pyrazolopyridine derivative, most closely related to pyrazolopyrimidine drugs such as zaleplon, and is one of a structurally diverse group of drugs known as the nonbenzodiazepines which act at the same receptor targets as benzodiazepines but have distinct chemical structures. not to be confused with cartazolate. tracazolateclinical dataroutes ofadministrationby mouthatc codenonelegal statuslegal status in general: uncontrolled identifiers iupac name ethyl 4-(butylamino)-1-ethyl-6-methyl-1h-pyrazolopyridine-5-carboxylate cas number41094-88-6pubchem cid5522iuphar/bps5467chemspider5321uniinh0hpl3u1tkeggd06200chebichebi:92596chemblchembl84567comptox dashboard (epa)dtxsid3046956 echa infocard100.050.178 chemical and physical dataformulac16h24n4o2molar mass304.394 g·mol−13d model (jsmol)interactive image smiles o=c(occ)c1c(c2c(nc1c)n(nc2)cc)ncccc inchi inchi=1s/c16h24n4o2/c1-5-8-9-17-14-12-10-18-20(6-2)15(12)19-11(4)13(14)16(21)22-7-3/h10h,5-9h2,1-4h3,(h,17,19)key:pctrymllrkwxgf-uhfffaoysa-n tracazolate has primarily anxiolytic and anticonvulsant effects, with sedative and muscle relaxant effects only appearing at higher doses. it has a unique receptor binding profile involving allosteric modulation of several gabaa receptor subtypes, being selective for gabaa receptors containing α1 and β3 subunits, but exhibiting different effects depending on the third type of subunit making up the receptor complex.