AdultPediatricDosage Forms & Strengths albuterol/budesonide inhalation aerosol 90mcg/80mcg per actuation Asthma Fixed dose inhaler indicated for as needed treatment or prevention of bronchoconstriction and for prevention of exacerbations in adults with asthma 2 actuations inhaled PO PRN for asthma symptoms 2 actuations = albuterol 180 mcg and budesonide 160 mcg Not to exceed 6 doses (12 inhalations) per 24 hr Dosage Modifications Renal impairment Formal pharmacokinetic studies have not been conducted Hepatic impairment Formal pharmacokinetic studies have not been conducted Budesonide is predominately cleared by hepatic metabolism and hepatic impairment may lead to plasma accumulation Monitor patients with hepatic impairment Dosing Considerations Not for use as maintenance treatment for asthma<18 years: Safety and efficacy not established Interaction CheckerEnter a drug name and albuterol/budesonide inhaledNo Results No Interactions Found Interactions FoundContraindicatedSerious - Use AlternativeSignificant - Monitor CloselyMinorAll Interactions Sort By: SeverityName Contraindicated (4)cisapridealbuterol and cisapride both increase QTc interval. Contraindicated.dronedaronealbuterol and dronedarone both increase QTc interval. Contraindicated.saquinavirsaquinavir, albuterol. Either increases toxicity of the other by pharmacodynamic synergism. Contraindicated. Contraindicated. Saquinavir boosted with ritonavir increases risk of hypokalemia, QT prolongation, and cardiac arrhythmias.thioridazinealbuterol and thioridazine both increase QTc interval. Contraindicated.Serious - Use Alternative (16)amitriptylineamitriptyline, albuterol. Other (see comment). Avoid or Use Alternate Drug. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron.amoxapineamoxapine, albuterol. Other (see comment). Avoid or Use Alternate Drug. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron.azithromycinalbuterol and azithromycin both increase QTc interval. Avoid or Use Alternate Drug.clomipramineclomipramine, albuterol. Other (see comment). Avoid or Use Alternate Drug. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron.desipraminedesipramine, albuterol. Other (see comment). Avoid or Use Alternate Drug. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron.doxepindoxepin, albuterol. Other (see comment). Avoid or Use Alternate Drug. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron.fexinidazolefexinidazole and albuterol both increase QTc interval. Avoid or Use Alternate Drug. Avoid coadministration of fexinidazole with drugs known to block potassium channels and/or prolong QT interval.hydroxychloroquine sulfatealbuterol and hydroxychloroquine sulfate both increase QTc interval. Avoid or Use Alternate Drug.imipramineimipramine, albuterol. Other (see comment). Avoid or Use Alternate Drug. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron.isocarboxazidisocarboxazid increases effects of albuterol by pharmacodynamic synergism. Contraindicated. Risk of acute hypertensive episode.linezolidlinezolid increases effects of albuterol by pharmacodynamic synergism. Contraindicated. Risk of acute hypertensive episode.lofepraminelofepramine, albuterol. Other (see comment). Avoid or Use Alternate Drug. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron.lonafarniblonafarnib will increase the level or effect of budesonide inhaled by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Avoid coadministration with sensitive CYP3A substrates. If coadministration unavoidable, monitor for adverse reactions and reduce CYP3A substrate dose in accordance with product labeling.lopinaviralbuterol and lopinavir both increase QTc interval. Avoid or Use Alternate Drug.macimorelinbudesonide inhaled, macimorelin. unspecified interaction mechanism. Avoid or Use Alternate Drug. Drugs that directly affect the pituitary secretion of growth hormone (GH) may impact the accuracy of the macimorelin diagnostic test. Allow sufficient washout time of drugs affecting GH growth hormone release before administering prior to administration of macimorelin. Drugs that directly affect the pituitary secretion of growth hormone (GH) may impact the accuracy of the macimorelin diagnostic test. Allow sufficient washout time of drugs affecting GH release before administering macimorelin.maprotilinemaprotiline, albuterol. Other (see comment). Avoid or Use Alternate Drug. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron.Monitor Closely (302)acebutololacebutolol increases and albuterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.acebutolol decreases effects of albuterol by pharmacodynamic antagonism. Use Caution/Monitor.aceclofenacaceclofenac increases and albuterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.acemetacinacemetacin increases and albuterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.alfentanilalfentanil increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.alprazolamalprazolam increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.amilorideamiloride increases and albuterol decreases serum potassium. Effect of interaction is not clear, use caution. Modify Therapy/Monitor Closely.amiodaronealbuterol and amiodarone both increase QTc interval. Use Caution/Monitor.amisulpridealbuterol and amisulpride both increase QTc interval. Use Caution/Monitor.amisulpride and albuterol both increase QTc interval. Use Caution/Monitor. ECG monitoring is recommended if coadministered.amitriptylineamitriptyline increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.albuterol and amitriptyline both increase QTc interval. Use Caution/Monitor.amobarbitalamobarbital increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.amoxapineamoxapine increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.anagrelidealbuterol and anagrelide both increase QTc interval. Use Caution/Monitor.apomorphinealbuterol and apomorphine both increase QTc interval. Use Caution/Monitor.arformoterolalbuterol and arformoterol both decrease serum potassium. Use Caution/Monitor.albuterol and arformoterol both decrease sedation. Use Caution/Monitor.albuterol and arformoterol both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.aripiprazolearipiprazole increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.armodafinilalbuterol and armodafinil both decrease sedation. Use Caution/Monitor.arsenic trioxidealbuterol and arsenic trioxide both increase QTc interval. Use Caution/Monitor.artemether/lumefantrinealbuterol and artemether/lumefantrine both increase QTc interval. Use Caution/Monitor.asenapinealbuterol and asenapine both increase QTc interval. Use Caution/Monitor.asenapine transdermalasenapine transdermal and albuterol both increase QTc interval. Use Caution/Monitor.aspirinaspirin increases and albuterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.aspirin rectalaspirin rectal increases and albuterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor. .aspirin/citric acid/sodium bicarbonateaspirin/citric acid/sodium bicarbonate increases and albuterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.atenololatenolol increases and albuterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.atenolol decreases effects of albuterol by pharmacodynamic antagonism. Use Caution/Monitor.atomoxetineatomoxetine, albuterol. Either increases effects of the other by pharmacodynamic synergism. Use Caution/Monitor. Risk of tachycardia, increased blood pressure.azelastineazelastine increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.bedaquilinealbuterol and bedaquiline both increase QTc interval. Use Caution/Monitor.belladonna and opiumbelladonna and opium increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.bendroflumethiazidealbuterol and bendroflumethiazide both decrease serum potassium. Use Caution/Monitor.benperidolbenperidol increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.benzphetaminealbuterol and benzphetamine both decrease sedation. Use Caution/Monitor.albuterol and benzphetamine both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.betaxololbetaxolol increases and albuterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.betaxolol decreases effects of albuterol by pharmacodynamic antagonism. Use Caution/Monitor.bisoprololbisoprolol increases and albuterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.bisoprolol decreases effects of albuterol by pharmacodynamic antagonism. Use Caution/Monitor.brompheniraminebrompheniramine increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.bumetanidealbuterol and bumetanide both decrease serum potassium. Use Caution/Monitor.buprenorphinebuprenorphine increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.albuterol and buprenorphine both increase QTc interval. Use Caution/Monitor.buprenorphine buccalbuprenorphine buccal increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.buprenorphine buccal and albuterol both increase QTc interval. Use Caution/Monitor.buprenorphine subdermal implantbuprenorphine subdermal implant and albuterol both increase QTc interval. Use Caution/Monitor.buprenorphine transdermalbuprenorphine transdermal and albuterol both increase QTc interval. Use Caution/Monitor.buprenorphine, long-acting injectionbuprenorphine, long-acting injection and albuterol both increase QTc interval. Use Caution/Monitor.butabarbitalbutabarbital increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.butalbitalbutalbital increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.butorphanolbutorphanol increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.caffeinealbuterol and caffeine both decrease sedation. Use Caution/Monitor.carbenoxolonealbuterol and carbenoxolone both decrease serum potassium. Use Caution/Monitor.carbinoxaminecarbinoxamine increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.carvedilolcarvedilol increases and albuterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.carvedilol decreases effects of albuterol by pharmacodynamic antagonism. Use Caution/Monitor.celecoxibcelecoxib increases and albuterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.celiprololceliprolol increases and albuterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.celiprolol decreases effects of albuterol by pharmacodynamic antagonism. Use Caution/Monitor.chloral hydratechloral hydrate increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.chlordiazepoxidechlordiazepoxide increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.chloroquinealbuterol and chloroquine both increase QTc interval. Use Caution/Monitor.chlorothiazidealbuterol and chlorothiazide both decrease serum potassium. Use Caution/Monitor.chlorpheniraminechlorpheniramine increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.chlorpromazinechlorpromazine increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.albuterol and chlorpromazine both increase QTc interval. Use Caution/Monitor.chlorthalidonealbuterol and chlorthalidone both decrease serum potassium. Use Caution/Monitor.choline magnesium trisalicylatecholine magnesium trisalicylate increases and albuterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor. .cinnarizinecinnarizine increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.ciprofloxacinalbuterol and ciprofloxacin both increase QTc interval. Use Caution/Monitor.citalopramalbuterol and citalopram both increase QTc interval. Use Caution/Monitor.clarithromycinalbuterol and clarithromycin both increase QTc interval. Use Caution/Monitor.clemastineclemastine increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.clomipramineclomipramine increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.clonazepamclonazepam increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.clorazepateclorazepate increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.clozapineclozapine increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.albuterol and clozapine both increase QTc interval. Use Caution/Monitor.cobicistatcobicistat increases levels of budesonide inhaled by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.codeinecodeine increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.crizotinibalbuterol and crizotinib both increase QTc interval. Use Caution/Monitor.cyclizinecyclizine increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.cyclopenthiazidealbuterol and cyclopenthiazide both decrease serum potassium. Use Caution/Monitor.cyproheptadinecyproheptadine increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.dasatinibalbuterol and dasatinib both increase QTc interval. Use Caution/Monitor.deflazacortalbuterol and deflazacort both decrease serum potassium. Use Caution/Monitor.degarelixalbuterol and degarelix both increase QTc interval. Use Caution/Monitor.desipraminedesipramine increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.albuterol and desipramine both increase QTc interval. Use Caution/Monitor.deutetrabenazinealbuterol and deutetrabenazine both increase QTc interval. Use Caution/Monitor. At the maximum recommended dose, deutetrabenazine does not prolong QT interval to a clinically relevant extent. Certain circumstances may increase risk of torsade de pointes and/or sudden death in association with drugs that prolong the QTc interval (eg, bradycardia, hypokalemia or hypomagnesemia, coadministration with other drugs that prolong QTc interval, presence of congenital QT prolongation).dexchlorpheniraminedexchlorpheniramine increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.dexfenfluraminealbuterol and dexfenfluramine both decrease sedation. Use Caution/Monitor.albuterol and dexfenfluramine both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.dexmedetomidinedexmedetomidine increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.dexmethylphenidatealbuterol and dexmethylphenidate both decrease sedation. Use Caution/Monitor.albuterol and dexmethylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.dextroamphetaminealbuterol and dextroamphetamine both decrease sedation. Use Caution/Monitor.albuterol and dextroamphetamine both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.dextromoramidedextromoramide increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.diamorphinediamorphine increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.dichlorphenamidedichlorphenamide and albuterol both decrease serum potassium. Use Caution/Monitor.dichlorphenamide, albuterol. Either increases levels of the other by pharmacodynamic synergism. Modify Therapy/Monitor Closely. Both drugs can cause metabolic acidosis.diclofenacdiclofenac increases and albuterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.diethylpropionalbuterol and diethylpropion both decrease sedation. Use Caution/Monitor.albuterol and diethylpropion both increase sympathetic