use caution. Use Caution/Monitor.meclofenamatemeclofenamate increases and epinephrine racemic decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.mefenamic acidmefenamic acid increases and epinephrine racemic decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.melatoninmelatonin increases and epinephrine racemic decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.meloxicammeloxicam increases and epinephrine racemic decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.meperidinemeperidine increases and epinephrine racemic decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.meprobamatemeprobamate increases and epinephrine racemic decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.metaproterenolmetaproterenol and epinephrine racemic both decrease serum potassium. Use Caution/Monitor.metaproterenol and epinephrine racemic both decrease sedation. Use Caution/Monitor.metaproterenol and epinephrine racemic both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.methadoneepinephrine racemic and methadone both increase QTc interval. Modify Therapy/Monitor Closely.methadone increases and epinephrine racemic decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.methamphetamineepinephrine racemic and methamphetamine both decrease sedation. Use Caution/Monitor.epinephrine racemic and methamphetamine both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.methyclothiazideepinephrine racemic and methyclothiazide both decrease serum potassium. Use Caution/Monitor.methylenedioxymethamphetamineepinephrine racemic and methylenedioxymethamphetamine both decrease sedation. Use Caution/Monitor.epinephrine racemic and methylenedioxymethamphetamine both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.methylphenidateepinephrine racemic and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.metolazoneepinephrine racemic and metolazone both decrease serum potassium. Use Caution/Monitor.metoprololmetoprolol increases and epinephrine racemic decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.metoprolol decreases effects of epinephrine racemic by pharmacodynamic antagonism. Use Caution/Monitor.midazolammidazolam increases and epinephrine racemic decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.midodrineepinephrine racemic and midodrine both decrease sedation. Use Caution/Monitor.epinephrine racemic and midodrine both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.mirtazapinemirtazapine increases and epinephrine racemic decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.modafinilepinephrine racemic and modafinil both decrease sedation. Use Caution/Monitor.morphinemorphine increases and epinephrine racemic decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.motherwortmotherwort increases and epinephrine racemic decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.moxonidinemoxonidine increases and epinephrine racemic decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.nabilonenabilone increases and epinephrine racemic decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.nabumetonenabumetone increases and epinephrine racemic decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.nadololnadolol increases and epinephrine racemic decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.nadolol decreases effects of epinephrine racemic by pharmacodynamic antagonism. Use Caution/Monitor.nalbuphinenalbuphine increases and epinephrine racemic decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.naproxennaproxen increases and epinephrine racemic decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.nebivololnebivolol increases and epinephrine racemic decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.nebivolol decreases effects of epinephrine racemic by pharmacodynamic antagonism. Use Caution/Monitor.norepinephrinenorepinephrine and epinephrine racemic both decrease serum potassium. Use Caution/Monitor.norepinephrine and epinephrine racemic both decrease sedation. Use Caution/Monitor.norepinephrine and epinephrine racemic both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.nortriptylinenortriptyline increases and epinephrine racemic decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.nortriptyline increases effects of epinephrine racemic by unknown mechanism. Use Caution/Monitor.ofloxacinepinephrine racemic and ofloxacin both increase QTc interval. Modify Therapy/Monitor Closely.olanzapineolanzapine increases and epinephrine racemic decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.olodaterol inhaledepinephrine racemic and olodaterol inhaled both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor. Caution with coadministration of adrenergic drugs by any route because of additive sympathetic effectsopicaponeopicapone will increase the level or effect of epinephrine racemic by decreasing metabolism. Use Caution/Monitor. Opicapone is a COMT inhibitor. Caution if coadministered with drugs metabolized by COMT. If coadministered, monitor for changes in heart rate, heart rhythm, and blood pressure.opium tinctureopium tincture increases and epinephrine racemic decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.oxaprozinoxaprozin increases and epinephrine racemic decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.oxazepamoxazepam increases and epinephrine racemic decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.oxycodoneoxycodone increases and epinephrine racemic decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.oxymorphoneoxymorphone increases and epinephrine racemic decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.paliperidoneepinephrine racemic and paliperidone both increase QTc interval. Modify Therapy/Monitor Closely.paliperidone increases and epinephrine racemic decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.papaveretumpapaveretum increases and epinephrine racemic decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.parecoxibparecoxib increases and epinephrine racemic decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.paroxetineepinephrine racemic and paroxetine both increase QTc interval. Modify Therapy/Monitor Closely.penbutololpenbutolol increases and epinephrine racemic decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.penbutolol decreases effects of epinephrine racemic by pharmacodynamic antagonism. Use Caution/Monitor.pentazocinepentazocine increases and epinephrine racemic decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.pentobarbitalpentobarbital increases and epinephrine racemic decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.perphenazineperphenazine increases and epinephrine racemic decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.perphenazine decreases effects of epinephrine racemic by pharmacodynamic antagonism. Use Caution/Monitor. Block pressor response to epinephrine, which may result in severe hypotension and tachycardia.phendimetrazineepinephrine racemic and phendimetrazine both decrease sedation. Use Caution/Monitor.epinephrine racemic and phendimetrazine both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.phenobarbitalphenobarbital increases and epinephrine racemic decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.phenoxybenzaminephenoxybenzamine, epinephrine racemic. Mechanism: pharmacodynamic synergism. Use Caution/Monitor. Hypotension, tachycardia.phentermineepinephrine racemic and phentermine both decrease sedation. Use Caution/Monitor.epinephrine racemic and phentermine both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.phentolaminephentolamine, epinephrine racemic. Mechanism: pharmacodynamic synergism. Use Caution/Monitor. Hypotension, tachycardia.phenylephrineepinephrine racemic and phenylephrine both decrease sedation. Use Caution/Monitor.epinephrine racemic and phenylephrine both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.phenylephrine POepinephrine racemic and phenylephrine PO both decrease sedation. Use Caution/Monitor.epinephrine racemic and phenylephrine PO both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.pholcodinepholcodine increases and epinephrine racemic decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.pimozidepimozide increases and epinephrine racemic decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.pindololpindolol increases and epinephrine racemic decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.pindolol decreases effects of epinephrine racemic by pharmacodynamic antagonism. Use Caution/Monitor.pirbuterolpirbuterol and epinephrine racemic both decrease serum potassium. Use Caution/Monitor.pirbuterol and epinephrine racemic both decrease sedation. Use Caution/Monitor.pirbuterol and epinephrine racemic both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.piroxicampiroxicam increases and epinephrine racemic decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.posaconazoleepinephrine racemic and posaconazole both increase QTc interval. Modify Therapy/Monitor Closely.potassium acid phosphatepotassium acid phosphate increases and epinephrine racemic decreases serum potassium. Effect of interaction is not clear, use caution. Modify Therapy/Monitor Closely.potassium chloridepotassium chloride increases and epinephrine racemic decreases serum potassium. Effect of interaction is not clear, use caution. Modify Therapy/Monitor Closely.potassium citratepotassium citrate increases and epinephrine racemic decreases serum potassium. Effect of interaction is not clear, use caution. Modify Therapy/Monitor Closely.primidoneprimidone increases and epinephrine racemic decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.prochlorperazineprochlorperazine increases and epinephrine racemic decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.prochlorperazine decreases effects of epinephrine racemic by pharmacodynamic antagonism. Use Caution/Monitor. Block pressor response to epinephrine, which may result in severe hypotension and tachycardia.promazinepromazine decreases effects of epinephrine racemic by pharmacodynamic antagonism. Use Caution/Monitor. Block pressor response to epinephrine, which may result in severe hypotension and tachycardia.promethazinepromethazine increases and epinephrine racemic decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.promethazine decreases effects of epinephrine racemic by pharmacodynamic antagonism. Use Caution/Monitor. Block pressor response to epinephrine, which may result in severe hypotension and tachycardia.propranololpropranolol increases and epinephrine racemic decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.propranolol decreases effects of epinephrine racemic by pharmacodynamic antagonism. Use Caution/Monitor.propylhexedrineepinephrine racemic and propylhexedrine both decrease sedation. Use Caution/Monitor.epinephrine racemic and propylhexedrine both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.protriptylineprotriptyline increases and epinephrine racemic decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.protriptyline increases effects of epinephrine racemic by unknown mechanism. Use Caution/Monitor.pseudoephedrineepinephrine racemic and pseudoephedrine both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.quazepamquazepam increases and epinephrine racemic decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.quetiapinequetiapine increases and epinephrine racemic decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.ranolazineepinephrine racemic and ranolazine both increase QTc interval. Modify Therapy/Monitor Closely.risperidoneepinephrine racemic and risperidone both increase QTc interval. Modify Therapy/Monitor Closely.risperidone increases and epinephrine racemic decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.romidepsinepinephrine racemic and romidepsin both increase QTc interval. Modify Therapy/Monitor Closely.sacubitril/valsartansacubitril/valsartan increases and epinephrine racemic decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.salicylates (non-asa)salicylates (non-asa) increases and epinephrine racemic decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.salmeterolepinephrine racemic and salmeterol both decrease serum potassium. Use Caution/Monitor.epinephrine racemic and salmeterol both decrease sedation. Use Caution/Monitor.epinephrine racemic and salmeterol both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.salsalatesalsalate increases and epinephrine racemic decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.scullcapscullcap increases and epinephrine racemic decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.secobarbitalsecobarbital increases and epinephrine racemic decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.serdexmethylphenidate/dexmethylphenidateepinephrine racemic and serdexmethylphenidate/dexmethylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.shepherd's purseshepherd's purse increases and epinephrine racemic decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.sodium sulfate/potassium chloride/magnesium sulfate/polyethylene glycolepinephrine racemic and sodium sulfate/potassium chloride/magnesium sulfate/polyethylene glycol both decrease serum potassium. Modify Therapy/Monitor Closely.solriamfetolepinephrine racemic and solriamfetol both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.sotalolsotalol increases and epinephrine racemic decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.sotalol decreases effects of epinephrine racemic by pharmacodynamic antagonism. Use Caution/Monitor.spironolactonespironolactone increases and epinephrine racemic decreases serum potassium. Effect of interaction is not clear, use caution. Modify Therapy/Monitor Closely.succinylcholinesuccinylcholine increases and epinephrine racemic decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.sufentanilsufentanil increases and epinephrine racemic decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.sulfamethoxazoleepinephrine racemic and sulfamethoxazole both increase QTc interval. Modify Therapy/Monitor Closely.sulfasalazinesulfasalazine increases and epinephrine racemic decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.sulindacsulindac increases and epinephrine racemic decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.tapentadoltapentadol increases and epinephrine racemic decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.telavancinepinephrine racemic and telavancin both increase QTc interval. Modify Therapy/Monitor Closely.temazepamtemazepam increases and epinephrine racemic decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.terbutalineepinephrine racemic and terbutaline both decrease serum potassium. Use Caution/Monitor.epinephrine racemic and terbutaline both decrease sedation. Use Caution/Monitor.epinephrine racemic and terbutaline both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.thioridazinethioridazine increases and epinephrine racemic decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.thioridazine decreases effects of epinephrine racemic by pharmacodynamic antagonism. Use Caution/Monitor. Block pressor response to epinephrine, which may result in severe hypotension and tachycardia.thiothixenethiothixene increases and epinephrine racemic decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.timololtimolol increases and epinephrine racemic decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.timolol decreases effects of epinephrine racemic by pharmacodynamic antagonism. Use Caution/Monitor.tolcaponetolcapone will increase the level or effect of epinephrine racemic by decreasing metabolism. Use Caution/Monitor. Tolcapone is a COMT inhibitor. Caution if coadministered with drugs metabolized by COMT. If coadministered, monitor for changes in heart rate, heart rhythm, and blood pressure.tolfenamic acidtolfenamic acid increases and epinephrine racemic decreases serum potassium. Effect of