drugs with known arrhythmogenic properties.paliperidonepaliperidone increases effects of glycopyrrolate inhaled by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.glycopyrrolate inhaled decreases levels of paliperidone by pharmacodynamic antagonism. Use Caution/Monitor.glycopyrrolate inhaled decreases levels of paliperidone by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.paliperidone increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.formoterol and paliperidone both increase QTc interval. Modify Therapy/Monitor Closely.pancuroniumglycopyrrolate inhaled and pancuronium both decrease cholinergic effects/transmission. Use Caution/Monitor.papaveretumpapaveretum increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.parecoxibparecoxib increases and formoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.paroxetineformoterol and paroxetine both increase QTc interval. Modify Therapy/Monitor Closely.pasireotideformoterol and pasireotide both increase QTc interval. Modify Therapy/Monitor Closely.pazopanibformoterol and pazopanib both increase QTc interval. Use Caution/Monitor.penbutololpenbutolol increases and formoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.penbutolol decreases effects of formoterol by pharmacodynamic antagonism. Use Caution/Monitor.pentazocinepentazocine increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.pentobarbitalpentobarbital increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.perphenazineperphenazine increases toxicity of glycopyrrolate inhaled by unknown mechanism. Use Caution/Monitor.glycopyrrolate inhaled decreases levels of perphenazine by pharmacodynamic antagonism. Use Caution/Monitor.perphenazine increases effects of glycopyrrolate inhaled by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.glycopyrrolate inhaled decreases levels of perphenazine by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.perphenazine increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.phendimetrazineformoterol and phendimetrazine both decrease sedation. Use Caution/Monitor.formoterol and phendimetrazine both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.physostigminephysostigmine increases and glycopyrrolate inhaled decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.phenobarbitalphenobarbital increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.phenoxybenzaminephenoxybenzamine, formoterol. Mechanism: pharmacodynamic synergism. Use Caution/Monitor. Hypotension, tachycardia.phentermineformoterol and phentermine both decrease sedation. Use Caution/Monitor.formoterol and phentermine both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.phenylephrineformoterol and phenylephrine both decrease sedation. Use Caution/Monitor.formoterol and phenylephrine both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.phenylephrine POformoterol and phenylephrine PO both decrease sedation. Use Caution/Monitor.formoterol and phenylephrine PO both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.pholcodinepholcodine increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.pilocarpinepilocarpine increases and glycopyrrolate inhaled decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.pimozideglycopyrrolate inhaled decreases levels of pimozide by pharmacodynamic antagonism. Use Caution/Monitor.pimozide increases effects of glycopyrrolate inhaled by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.glycopyrrolate inhaled decreases levels of pimozide by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.pimozide increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.pindololpindolol increases and formoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.pindolol decreases effects of formoterol by pharmacodynamic antagonism. Use Caution/Monitor.pralidoximeglycopyrrolate inhaled and pralidoxime both decrease cholinergic effects/transmission. Use Caution/Monitor.pirbuterolformoterol and pirbuterol both decrease serum potassium. Use Caution/Monitor.formoterol and pirbuterol both decrease sedation. Use Caution/Monitor.formoterol and pirbuterol both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.piroxicampiroxicam increases and formoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.posaconazoleformoterol and posaconazole both increase QTc interval. Modify Therapy/Monitor Closely.potassium acid phosphatepotassium acid phosphate increases and formoterol decreases serum potassium. Effect of interaction is not clear, use caution. Modify Therapy/Monitor Closely.potassium chloridepotassium chloride increases and formoterol decreases serum potassium. Effect of interaction is not clear, use caution. Modify Therapy/Monitor Closely.potassium citratepotassium citrate increases and formoterol decreases serum potassium. Effect of interaction is not clear, use caution. Modify Therapy/Monitor Closely.primidoneprimidone increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.procarbazineprocarbazine increases effects of formoterol by pharmacodynamic synergism. Use Caution/Monitor.prochlorperazineglycopyrrolate inhaled decreases levels of prochlorperazine by pharmacodynamic antagonism. Use Caution/Monitor.prochlorperazine increases effects of glycopyrrolate inhaled by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.glycopyrrolate inhaled decreases levels of prochlorperazine by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.prochlorperazine increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.promethazinepromethazine increases effects of glycopyrrolate inhaled by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.glycopyrrolate inhaled decreases levels of promethazine by pharmacodynamic antagonism. Use Caution/Monitor.promethazine increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.glycopyrrolate inhaled decreases levels of promethazine by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.propanthelineglycopyrrolate inhaled and propantheline both decrease cholinergic effects/transmission. Use Caution/Monitor.propranololpropranolol increases and formoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.propranolol decreases effects of formoterol by pharmacodynamic antagonism. Use Caution/Monitor.propylhexedrineformoterol and propylhexedrine both decrease sedation. Use Caution/Monitor.formoterol and propylhexedrine both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.protriptylineprotriptyline increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.glycopyrrolate inhaled and protriptyline both decrease cholinergic effects/transmission. Use Caution/Monitor.protriptyline increases levels of glycopyrrolate inhaled by unknown mechanism. Use Caution/Monitor.pseudoephedrineformoterol and pseudoephedrine both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.pyridostigminepyridostigmine increases and glycopyrrolate inhaled decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.quazepamquazepam increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.quetiapineglycopyrrolate inhaled decreases levels of quetiapine by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.quetiapine increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.glycopyrrolate inhaled decreases levels of quetiapine by pharmacodynamic antagonism. Use Caution/Monitor.quetiapine increases effects of glycopyrrolate inhaled by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.quinineformoterol and quinine both increase QTc interval. Use Caution/Monitor.rapacuroniumglycopyrrolate inhaled and rapacuronium both decrease cholinergic effects/transmission. Use Caution/Monitor.ranolazineformoterol and ranolazine both increase QTc interval. Modify Therapy/Monitor Closely.ribociclibribociclib increases toxicity of formoterol by QTc interval. Use Caution/Monitor.rimantadineglycopyrrolate inhaled, rimantadine. Mechanism: pharmacodynamic synergism. Use Caution/Monitor. Enhanced CNS side effects.risperidonerisperidone increases effects of glycopyrrolate inhaled by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.formoterol and risperidone both increase QTc interval. Modify Therapy/Monitor Closely.glycopyrrolate inhaled decreases levels of risperidone by pharmacodynamic antagonism. Use Caution/Monitor.glycopyrrolate inhaled decreases levels of risperidone by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.risperidone increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.rivastigminerivastigmine increases and glycopyrrolate inhaled decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.sacubitril/valsartansacubitril/valsartan increases and formoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.rocuroniumglycopyrrolate inhaled and rocuronium both decrease cholinergic effects/transmission. Use Caution/Monitor.salicylates (non-asa)salicylates (non-asa) increases and formoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.salmeterolformoterol and salmeterol both decrease serum potassium. Use Caution/Monitor.formoterol and salmeterol both decrease sedation. Use Caution/Monitor.formoterol and salmeterol both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.salsalatesalsalate increases and formoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.scopolamineglycopyrrolate inhaled and scopolamine both decrease cholinergic effects/transmission. Use Caution/Monitor.scullcapscullcap increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.secobarbitalsecobarbital increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.selpercatinibselpercatinib increases toxicity of formoterol by QTc interval. Use Caution/Monitor.serdexmethylphenidate/dexmethylphenidateformoterol and serdexmethylphenidate/dexmethylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.shepherd's purseshepherd's purse increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.sodium sulfate/potassium chloride/magnesium sulfate/polyethylene glycolformoterol and sodium sulfate/potassium chloride/magnesium sulfate/polyethylene glycol both decrease serum potassium. Modify Therapy/Monitor Closely.solifenacinglycopyrrolate inhaled and solifenacin both decrease cholinergic effects/transmission. Use Caution/Monitor.solriamfetolformoterol and solriamfetol both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.sorafenibsorafenib and formoterol both increase QTc interval. Use Caution/Monitor.sotalolsotalol increases and formoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.sotalol decreases effects of formoterol by pharmacodynamic antagonism. Use Caution/Monitor.spironolactonespironolactone increases and formoterol decreases serum potassium. Effect of interaction is not clear, use caution. Modify Therapy/Monitor Closely.succinylcholinesuccinylcholine increases and glycopyrrolate inhaled decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.succinylcholine increases and formoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.sufentanilsufentanil increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.thioridazineglycopyrrolate inhaled decreases levels of thioridazine by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.glycopyrrolate inhaled decreases levels of thioridazine by pharmacodynamic antagonism. Use Caution/Monitor.thioridazine increases effects of glycopyrrolate inhaled by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.sulfamethoxazolesulfamethoxazole and formoterol both increase QTc interval. Modify Therapy/Monitor Closely.sulfasalazinesulfasalazine increases and formoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.sulindacsulindac increases and formoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.tapentadoltapentadol increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.telavancinformoterol and telavancin both increase QTc interval. Modify Therapy/Monitor Closely.temazepamtemazepam increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.terbutalineformoterol and terbutaline both decrease serum potassium. Use Caution/Monitor.formoterol and terbutaline both decrease sedation. Use Caution/Monitor.formoterol and terbutaline both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.thioridazinethioridazine increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.thiothixenethiothixene increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.glycopyrrolate inhaled decreases levels of thiothixene by pharmacodynamic antagonism. Use Caution/Monitor.glycopyrrolate inhaled decreases levels of thiothixene by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.thiothixene increases effects of glycopyrrolate inhaled by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.timololtimolol increases and formoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.timolol decreases effects of formoterol by pharmacodynamic antagonism. Use Caution/Monitor.tiotropiumglycopyrrolate inhaled and tiotropium both decrease cholinergic effects/transmission. Use Caution/Monitor.tolfenamic acidtolfenamic acid increases and formoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.tolmetintolmetin increases and formoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.tolterodineglycopyrrolate inhaled and tolterodine both decrease cholinergic effects/transmission. Use Caution/Monitor.tolvaptantolvaptan increases and formoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.topiramatetopiramate increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Modify Therapy/Monitor Closely.torsemideformoterol and torsemide both decrease serum potassium. Use Caution/Monitor.tramadoltramadol increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.trazodonetrazodone increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.triamterenetriamterene increases and formoterol decreases serum potassium. Effect of interaction is not clear, use caution. Modify Therapy/Monitor Closely.triazolamtriazolam increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.triclofostriclofos increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.trifluoperazinetrifluoperazine increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.glycopyrrolate inhaled decreases levels of trifluoperazine by pharmacodynamic antagonism. Use Caution/Monitor.trifluoperazine increases effects of glycopyrrolate inhaled by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.glycopyrrolate inhaled decreases levels of trifluoperazine by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.trihexyphenidylglycopyrrolate inhaled and trihexyphenidyl both decrease cholinergic effects/transmission. Use Caution/Monitor. Potential for additive anticholinergic effects.trimethoprimformoterol and trimethoprim both increase QTc interval. Modify Therapy/Monitor Closely.trimipraminetrimipramine increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.glycopyrrolate inhaled and trimipramine both decrease cholinergic effects/transmission. Use Caution/Monitor.trimipramine increases levels of glycopyrrolate inhaled by unknown mechanism. Use Caution/Monitor.triprolidinetriprolidine increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.trospium chlorideglycopyrrolate inhaled and trospium chloride both decrease cholinergic effects/transmission. Use Caution/Monitor.triptorelintriptorelin increases levels of formoterol by QTc interval. Use Caution/Monitor. Increases risk of torsades de pointes.tropisetronformoterol and tropisetron both increase QTc interval. Modify Therapy/Monitor Closely.umeclidinium bromideumeclidinium bromide and glycopyrrolate inhaled both decrease cholinergic effects/transmission. Use Caution/Monitor. If possible, avoid coadministration of additional anticholinergic agents vecuroniumglycopyrrolate inhaled and vecuronium both decrease cholinergic effects/transmission. Use Caution/Monitor.venlafaxineformoterol