AdultPediatricDosage Forms & Strengths tablet 5mg 10mg 25mg 50mg Urinary Retention 10-50 mg PO three/four times daily Some patients may require doses of 50-100 mg PO twice daily Take 1 hour AC or 2 hours PC GERD (Off-label) 25 mg PO four times daily Take 1 hour AC or 2 hours PCDosage Forms & Strengths tablet 5mg 10mg 25mg 50mg Urinary Retention (Off-label) 0.3-0.6 mg/kg/day PO divided three/four times daily Take 1 hour AC or 2 hours PC GERD (Off-label) 0.3-0.6 mg/kg/day PO divided four times daily Take 1 hour AC or 2 hours PCInteraction CheckerEnter a drug name and bethanecholNo Results No Interactions Found Interactions FoundContraindicatedSerious - Use AlternativeSignificant - Monitor CloselyMinorAll Interactions Sort By: SeverityName Contraindicated (0)Serious - Use Alternative (0)Monitor Closely (65)aclidiniumbethanechol increases and aclidinium decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.amifampridineamifampridine and bethanechol both increase cholinergic effects/transmission. Use Caution/Monitor.amitriptylinebethanechol increases and amitriptyline decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Modify Therapy/Monitor Closely.amoxapinebethanechol increases and amoxapine decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.anticholinergic/sedative combosbethanechol increases and anticholinergic/sedative combos decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.atracuriumbethanechol increases and atracurium decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.atropinebethanechol increases and atropine decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.atropine IV/IMbethanechol increases and atropine IV/IM decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor. .belladonna alkaloidsbethanechol increases and belladonna alkaloids decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.belladonna and opiumbethanechol increases and belladonna and opium decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.carbacholbethanechol and carbachol both increase cholinergic effects/transmission. Use Caution/Monitor.cevimelinebethanechol and cevimeline both increase cholinergic effects/transmission. Use Caution/Monitor.cisatracuriumbethanechol increases and cisatracurium decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.clomipraminebethanechol increases and clomipramine decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.cyclizinebethanechol increases and cyclizine decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.cyclobenzaprinebethanechol increases and cyclobenzaprine decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.darifenacinbethanechol increases and darifenacin decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.dicyclominebethanechol increases and dicyclomine decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.diphenhydraminebethanechol increases and diphenhydramine decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.donepezilbethanechol and donepezil both increase cholinergic effects/transmission. Use Caution/Monitor.dosulepinbethanechol increases and dosulepin decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.doxepinbethanechol increases and doxepin decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.echothiophate iodidebethanechol and echothiophate iodide both increase cholinergic effects/transmission. Use Caution/Monitor.fesoterodinebethanechol increases and fesoterodine decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.flavoxatebethanechol increases and flavoxate decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.galantaminebethanechol and galantamine both increase cholinergic effects/transmission. Use Caution/Monitor.glycopyrrolatebethanechol increases and glycopyrrolate decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.glycopyrrolate inhaledbethanechol increases and glycopyrrolate inhaled decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.henbanebethanechol increases and henbane decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.homatropinebethanechol increases and homatropine decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.huperzine Abethanechol and huperzine A both increase cholinergic effects/transmission. Use Caution/Monitor.hyoscyaminebethanechol increases and hyoscyamine decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.hyoscyamine spraybethanechol increases and hyoscyamine spray decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor. .imipraminebethanechol increases and imipramine decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.ipratropiumbethanechol increases and ipratropium decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.lofepraminebethanechol increases and lofepramine decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.maprotilinebethanechol increases and maprotiline decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.meclizinebethanechol increases and meclizine decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.methscopolaminebethanechol increases and methscopolamine decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.neostigminebethanechol and neostigmine both increase cholinergic effects/transmission. Use Caution/Monitor.nortriptylinebethanechol increases and nortriptyline decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.onabotulinumtoxinAbethanechol increases and onabotulinumtoxinA decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.orphenadrinebethanechol increases and orphenadrine decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.oxybutyninbethanechol increases and oxybutynin decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.oxybutynin topicalbethanechol increases and oxybutynin topical decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.oxybutynin transdermalbethanechol increases and oxybutynin transdermal decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.pancuroniumbethanechol increases and pancuronium decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.physostigminebethanechol and physostigmine both increase cholinergic effects/transmission. Use Caution/Monitor.pilocarpinebethanechol and pilocarpine both increase cholinergic effects/transmission. Use Caution/Monitor.pralidoximebethanechol increases and pralidoxime decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.propanthelinebethanechol increases and propantheline decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.protriptylinebethanechol increases and protriptyline decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.pyridostigminebethanechol and pyridostigmine both increase cholinergic effects/transmission. Use Caution/Monitor.rapacuroniumbethanechol increases and rapacuronium decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.rivastigminebethanechol and rivastigmine both increase cholinergic effects/transmission. Use Caution/Monitor.rivastigmine and bethanechol both increase cholinergic effects/transmission. Use Caution/Monitor.rocuroniumbethanechol increases and rocuronium decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.scopolaminebethanechol increases and scopolamine decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.solifenacinbethanechol increases and solifenacin decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.succinylcholinebethanechol and succinylcholine both increase cholinergic effects/transmission. Use Caution/Monitor.tiotropiumbethanechol increases and tiotropium decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.tolterodinebethanechol increases and tolterodine decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.trimipraminebethanechol increases and trimipramine decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.trospium chloridebethanechol increases and trospium chloride decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.umeclidinium bromidebethanechol increases and umeclidinium bromide decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor. Monitor when umeclidinium bromide is coadministered with cholinergic agents.vecuroniumbethanechol increases and vecuronium decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.Minor (7)desipraminebethanechol increases and desipramine decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Minor/Significance Unknown.donepezildonepezil increases effects of bethanechol by pharmacodynamic synergism. Minor/Significance Unknown.galantaminegalantamine increases effects of bethanechol by pharmacodynamic synergism. Minor/Significance Unknown.mecamylaminemecamylamine, bethanechol. Mechanism: pharmacodynamic synergism. Minor/Significance Unknown. Additive hypotensive effects.pantothenic acidpantothenic acid, bethanechol. Either increases effects of the other by pharmacodynamic synergism. Minor/Significance Unknown.procainamideprocainamide decreases effects of bethanechol by pharmacodynamic antagonism. Minor/Significance Unknown.trazodonebethanechol increases and trazodone decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Minor/Significance Unknown.aclidiniumMonitor Closely (1)bethanechol increases and aclidinium decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.amifampridineMonitor Closely (1)amifampridine and bethanechol both increase cholinergic effects/transmission. Use Caution/Monitor.amitriptylineMonitor Closely (1)bethanechol increases and amitriptyline decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Modify Therapy/Monitor Closely.amoxapineMonitor Closely (1)bethanechol increases and amoxapine decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.anticholinergic/sedative combosMonitor Closely (1)bethanechol increases and anticholinergic/sedative combos decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.atracuriumMonitor Closely (1)bethanechol increases and atracurium decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.atropineMonitor Closely (1)bethanechol increases and atropine decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.atropine IV/IMMonitor Closely (1)bethanechol increases and atropine IV/IM decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor. .belladonna alkaloidsMonitor Closely (1)bethanechol increases and belladonna alkaloids decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.belladonna and opiumMonitor Closely (1)bethanechol increases and belladonna and opium decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.carbacholMonitor Closely (1)bethanechol and carbachol both increase cholinergic effects/transmission. Use Caution/Monitor.cevimelineMonitor Closely (1)bethanechol and cevimeline both increase cholinergic effects/transmission. Use Caution/Monitor.cisatracuriumMonitor Closely (1)bethanechol increases and cisatracurium decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.clomipramineMonitor Closely (1)bethanechol increases and clomipramine decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.cyclizineMonitor Closely (1)bethanechol increases and cyclizine decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.cyclobenzaprineMonitor Closely (1)bethanechol increases and cyclobenzaprine decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.darifenacinMonitor Closely (1)bethanechol increases and darifenacin decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.desipramineMinor (1)bethanechol increases and desipramine decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Minor/Significance Unknown.dicyclomineMonitor Closely (1)bethanechol increases and dicyclomine decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.diphenhydramineMonitor Closely (1)bethanechol increases and diphenhydramine decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.donepezilMonitor Closely (1)bethanechol and donepezil both increase cholinergic effects/transmission. Use Caution/Monitor.Minor (1)donepezil increases effects of bethanechol by pharmacodynamic synergism. Minor/Significance Unknown.dosulepinMonitor Closely (1)bethanechol increases and dosulepin decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.doxepinMonitor Closely (1)bethanechol increases and doxepin decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.echothiophate iodideMonitor Closely (1)bethanechol and echothiophate iodide both increase cholinergic effects/transmission. Use Caution/Monitor.fesoterodineMonitor Closely (1)bethanechol increases and fesoterodine decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.flavoxateMonitor Closely (1)bethanechol increases and flavoxate decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.galantamineMonitor Closely (1)bethanechol and galantamine both increase cholinergic effects/transmission. Use Caution/Monitor.Minor (1)galantamine increases effects of bethanechol by pharmacodynamic synergism. Minor/Significance Unknown.glycopyrrolateMonitor Closely (1)bethanechol increases and glycopyrrolate decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.glycopyrrolate inhaledMonitor Closely (1)bethanechol increases and glycopyrrolate inhaled decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.henbaneMonitor Closely (1)bethanechol increases and henbane decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.homatropineMonitor Closely (1)bethanechol increases and homatropine decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.huperzine AMonitor Closely (1)bethanechol and huperzine A both increase cholinergic effects/transmission. Use Caution/Monitor.hyoscyamineMonitor Closely (1)bethanechol increases and hyoscyamine decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.hyoscyamine sprayMonitor Closely (1)bethanechol increases and hyoscyamine spray decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor. .imipramineMonitor Closely (1)bethanechol increases and imipramine decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.ipratropiumMonitor Closely (1)bethanechol increases and ipratropium decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.lofepramineMonitor Closely (1)bethanechol increases and lofepramine decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.maprotilineMonitor Closely (1)bethanechol increases and maprotiline decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.mecamylamineMinor (1)mecamylamine, bethanechol. Mechanism: pharmacodynamic synergism. Minor/Significance Unknown. Additive hypotensive effects.meclizineMonitor Closely (1)bethanechol increases and meclizine decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.methscopolamineMonitor Closely (1)bethanechol increases and methscopolamine decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.neostigmineMonitor Closely (1)bethanechol and neostigmine both increase cholinergic effects/transmission. Use Caution/Monitor.nortriptylineMonitor Closely (1)bethanechol increases and nortriptyline decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.onabotulinumtoxinAMonitor Closely (1)bethanechol increases and onabotulinumtoxinA decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.orphenadrineMonitor Closely (1)bethanechol increases and orphenadrine decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.oxybutyninMonitor Closely (1)bethanechol increases and oxybutynin decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.oxybutynin topicalMonitor Closely (1)bethanechol increases and oxybutynin topical decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.oxybutynin transdermalMonitor Closely (1)bethanechol increases and oxybutynin transdermal decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.pancuroniumMonitor Closely (1)bethanechol increases and pancuronium decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.pantothenic acidMinor (1)pantothenic acid, bethanechol.