AdultPediatricDosage Forms & Strengths mometasone/formoterol aerosol (50mcg/5mcg)/actuation (100mcg/5mcg)/actuation (200mcg/5mcg)/actuation Asthma Indicated for asthma in patients who are not adequately controlled on a long-term asthma-control medication such as an inhaled corticosteroid (ICS) or whose disease warrants initiation of treatment with both an ICS and long-acting beta2-adrenergic agonist (LABA) Initial: 200 mcg/10 mcg (2 actuations of 100 mcg/5 mcg) inhaled PO q12hr; may increase to higher dose after 2 wk if inadequate response; maximum benefit may not be achieved for 1 week or longer after beginning treatment Severe asthma (initial) or inadequate response to lower dose (after 2 wk): 400 mcg/10 mcg (2 actuations of 200 mcg/5 mcg) inhaled PO q12hr Not to exceed more than 2 inhalations twice daily of prescribed strength Maximum daily dose: 800 mcg/20 mcg daily (ie, 2 actuations of 200 mcg/5 mcg q12hr)If therapy fails to provide adequate control of asthma, re-evaluate therapeutic regimen; consider replacing with higher strength, adding additional inhaled corticosteroid, or initiating oral corticosteroids If symptoms arise between doses, an inhaled short-acting beta2-agonist should be taken for immediate relief Dosing Considerations Limitation of use Not indicated for the relief of acute bronchospasm Dosage Forms & Strengths mometasone/formoterol aerosol (50mcg/5mcg)/actuation (100mcg/5mcg)/actuation (200mcg/5mcg)/actuation Asthma Indicated for asthma in patients who are not adequately controlled on a long-term asthma-control medication such as an inhaled corticosteroid (ICS) or whose disease warrants initiation of treatment with both an ICS and long-acting beta2-adrenergic agonist (LABA) <5 years: Safety and efficacy not established 5 to <12 years 100 mcg/10 mcg (2 actuations of 50 mcg/5 mcg) inhaled PO q12hr; maximum daily dosage is 200 mcg/20 mcg ≥12 years Initial: 200 mcg/10 mcg (2 actuations of 100 mcg/5 mcg) inhaled PO q12hr; may increase to higher dose after 2 wk if inadequate response; maximum benefit may not be achieved for 1 week or longer after beginning treatment Severe asthma (initial) or inadequate response to lower dose (after 2 wk): 400 mcg/10 mcg (2 actuations of 200 mcg/5 mcg) inhaled PO q12hr Not to exceed more than 2 inhalations twice daily of prescribed strength Maximum daily dose: 800 mcg/20 mcg daily (ie, 2 actuations of 200 mcg/5 mcg q12hr) If therapy fails to provide adequate control of asthma, re-evaluate therapeutic regimen; consider replacing with higher strength, adding additional inhaled corticosteroid, or initiating oral corticosteroids If symptoms arise between doses, an inhaled short-acting beta2-agonist should be taken for immediate relief Dosing Considerations Limitations of use Not indicated for the relief of acute bronchospasm Interaction CheckerEnter a drug name and mometasone inhaled/formoterolNo Results No Interactions Found Interactions FoundContraindicatedSerious - Use AlternativeSignificant - Monitor CloselyMinorAll Interactions Sort By: SeverityName Contraindicated (0)Serious - Use Alternative (43)adagrasibadagrasib, formoterol. Either increases effects of the other by QTc interval. Avoid or Use Alternate Drug. Each drug prolongs the QTc interval, which may increased the risk of Torsade de pointes, other serious arryhthmias, and sudden death. If coadministration unavoidable, more frequent monitoring is recommended for such patients.aldesleukinmometasone inhaled decreases effects of aldesleukin by Other (see comment). Avoid or Use Alternate Drug. Comment: Corticosteroids may interfere with antitumor effects of aldesleukin.amisulprideamisulpride and formoterol both increase QTc interval. Avoid or Use Alternate Drug. ECG monitoring is recommended if coadministered.amitriptylineamitriptyline and formoterol both increase QTc interval. Avoid or Use Alternate Drug.amitriptyline, formoterol. Other (see comment). Avoid or Use Alternate Drug. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron.amoxapineamoxapine and formoterol both increase QTc interval. Avoid or Use Alternate Drug.amoxapine, formoterol. Other (see comment). Avoid or Use Alternate Drug. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron.arformoterolarformoterol and formoterol both increase QTc interval. Avoid or Use Alternate Drug.artemether/lumefantrineformoterol and artemether/lumefantrine both increase QTc interval. Avoid or Use Alternate Drug.chlorpromazinechlorpromazine and formoterol both increase QTc interval. Avoid or Use Alternate Drug.clarithromycinclarithromycin and formoterol both increase QTc interval. Avoid or Use Alternate Drug.clomipramineclomipramine and formoterol both increase QTc interval. Avoid or Use Alternate Drug.clomipramine, formoterol. Other (see comment). Avoid or Use Alternate Drug. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron.desipraminedesipramine and formoterol both increase QTc interval. Avoid or Use Alternate Drug.desipramine, formoterol. Other (see comment). Avoid or Use Alternate Drug. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron.desmopressinmometasone inhaled increases toxicity of desmopressin by Other (see comment). Avoid or Use Alternate Drug. Comment: Corticosteroids may enhance the hyponatremic effect of intranasal desmopressin.disopyramidedisopyramide and formoterol both increase QTc interval. Avoid or Use Alternate Drug.dofetilidedofetilide and formoterol both increase QTc interval. Avoid or Use Alternate Drug.doxepindoxepin and formoterol both increase QTc interval. Avoid or Use Alternate Drug.doxepin, formoterol. Other (see comment). Avoid or Use Alternate Drug. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron.dronedaronedronedarone and formoterol both increase QTc interval. Avoid or Use Alternate Drug.droperidoldroperidol and formoterol both increase QTc interval. Avoid or Use Alternate Drug.entrectinibformoterol and entrectinib both increase QTc interval. Avoid or Use Alternate Drug.epinephrineepinephrine and formoterol both increase QTc interval. Avoid or Use Alternate Drug.epinephrine racemicepinephrine racemic and formoterol both increase QTc interval. Avoid or Use Alternate Drug.erythromycin baseerythromycin base and formoterol both increase QTc interval. Avoid or Use Alternate Drug.erythromycin ethylsuccinateerythromycin ethylsuccinate and formoterol both increase QTc interval. Avoid or Use Alternate Drug.erythromycin lactobionateerythromycin lactobionate and formoterol both increase QTc interval. Avoid or Use Alternate Drug.erythromycin stearateerythromycin stearate and formoterol both increase QTc interval. Avoid or Use Alternate Drug.fexinidazolefexinidazole and formoterol both increase QTc interval. Avoid or Use Alternate Drug. Avoid coadministration of fexinidazole with drugs known to block potassium channels or prolong QT interval.fluconazolefluconazole and formoterol both increase QTc interval. Avoid or Use Alternate Drug.fluphenazinefluphenazine and formoterol both increase QTc interval. Avoid or Use Alternate Drug.glasdegibformoterol and glasdegib both increase QTc interval. Avoid or Use Alternate Drug. If coadministration unavoidable, monitor for increased risk of QTc interval prolongation.haloperidolformoterol and haloperidol both increase QTc interval. Avoid or Use Alternate Drug.hydroxychloroquine sulfatehydroxychloroquine sulfate and formoterol both increase QTc interval. Avoid or Use Alternate Drug.ibutilideformoterol and ibutilide both increase QTc interval. Avoid or Use Alternate Drug.imipramineimipramine and formoterol both increase QTc interval. Avoid or Use Alternate Drug.imipramine, formoterol. Other (see comment). Avoid or Use Alternate Drug. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron.indapamideformoterol and indapamide both increase QTc interval. Avoid or Use Alternate Drug.inotuzumabinotuzumab and formoterol both increase QTc interval. Avoid or Use Alternate Drug. If unable to avoid concomitant use, obtain ECGs and electrolytes before and after initiation of any drug known to prolong QTc, and periodically monitor as clinically indicated during treatment.isocarboxazidisocarboxazid increases effects of formoterol by pharmacodynamic synergism. Contraindicated. Risk of acute hypertensive episode.ivosidenibivosidenib and formoterol both increase QTc interval. Avoid or Use Alternate Drug. Avoid coadministration of QTc prolonging drugs with ivosidenib or replace with alternate therapies. If coadministration of a QTc prolonging drug is unavoidable, monitor for increased risk of QTc interval prolongation.ketoconazoleformoterol and ketoconazole both increase QTc interval. Avoid or Use Alternate Drug.lefamulinlefamulin and formoterol both increase QTc interval. Avoid or Use Alternate Drug.levoketoconazoleformoterol and levoketoconazole both increase QTc interval. Avoid or Use Alternate Drug.linezolidlinezolid increases effects of formoterol by pharmacodynamic synergism. Contraindicated. Risk of acute hypertensive episode.lofepraminelofepramine and formoterol both increase QTc interval. Avoid or Use Alternate Drug.lofepramine, formoterol. Other (see comment). Avoid or Use Alternate Drug. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron.loxapine inhaledmometasone inhaled increases toxicity of loxapine inhaled by Other (see comment). Avoid or Use Alternate Drug. Comment: Agents used to treat airway disease may enhance the toxic effect of inhaled loxapine.lumefantrineformoterol and lumefantrine both increase QTc interval. Avoid or Use Alternate Drug.Monitor Closely (310)acebutololacebutolol increases and formoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.acebutolol decreases effects of formoterol by pharmacodynamic antagonism. Use Caution/Monitor.aceclofenacaceclofenac increases and formoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.acemetacinacemetacin increases and formoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.albuterolalbuterol and formoterol both decrease serum potassium. Use Caution/Monitor.albuterol and formoterol both decrease sedation. Use Caution/Monitor.albuterol and formoterol both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.alfentanilalfentanil increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.alfuzosinformoterol and alfuzosin both increase QTc interval. Use Caution/Monitor.alfuzosin and formoterol both increase QTc interval. Use Caution/Monitor.alprazolamalprazolam increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.amilorideamiloride increases and formoterol decreases serum potassium. Effect of interaction is not clear, use caution. Modify Therapy/Monitor Closely.amiodaroneamiodarone and formoterol both increase QTc interval. Use Caution/Monitor.amitriptylineamitriptyline increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.amobarbitalamobarbital increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.amoxapineamoxapine increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.amphotericin B deoxycholatemometasone inhaled increases toxicity of amphotericin B deoxycholate by Other (see comment). Use Caution/Monitor. Comment: Corticosteroids may enhance the hypokalemic effect of amphtericin B. .apomorphineapomorphine and formoterol both increase QTc interval. Use Caution/Monitor.arformoterolarformoterol and formoterol both decrease serum potassium. Use Caution/Monitor.arformoterol and formoterol both decrease sedation. Use Caution/Monitor.arformoterol and formoterol both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.aripiprazolearipiprazole increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.aripiprazole and formoterol both increase QTc interval. Use Caution/Monitor.armodafinilformoterol and armodafinil both decrease sedation. Use Caution/Monitor.arsenic trioxidearsenic trioxide and formoterol both increase QTc interval. Use Caution/Monitor.artemetherartemether and formoterol both increase QTc interval. Use Caution/Monitor.asenapine transdermalasenapine transdermal and formoterol both increase QTc interval. Use Caution/Monitor.aspirinaspirin increases and formoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.aspirin rectalaspirin rectal increases and formoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor. .aspirin/citric acid/sodium bicarbonateaspirin/citric acid/sodium bicarbonate increases and formoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.atazanaviratazanavir increases levels of mometasone inhaled by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Potential for increased toxicity. Increased risk of Cushing's syndrome or adrenal suppression.atenololatenolol increases and formoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.atenolol decreases effects of formoterol by pharmacodynamic antagonism. Use Caution/Monitor.atomoxetineformoterol, atomoxetine. Other (see comment). Use Caution/Monitor. Comment: Exercise caution if beta-agonists and atomoxetine are coadministered. Interaction may be less likely with inhaled beta-agonists versus those given systemically. .atomoxetine and formoterol both increase QTc interval. Use Caution/Monitor.azelastineazelastine increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.azithromycinazithromycin and formoterol both increase QTc interval. Use Caution/Monitor.bedaquilineformoterol and bedaquiline both increase QTc interval. Modify Therapy/Monitor Closely. ECG should be monitored closelybelladonna and opiumbelladonna and opium increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.bendroflumethiazideformoterol and bendroflumethiazide both decrease serum potassium. Use Caution/Monitor.benperidolbenperidol increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.benzphetamineformoterol and benzphetamine both decrease sedation. Use Caution/Monitor.formoterol and benzphetamine both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.betaxololbetaxolol increases and formoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.betaxolol decreases effects of formoterol by pharmacodynamic antagonism. Use Caution/Monitor.bisoprololbisoprolol increases and formoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.bisoprolol decreases effects of formoterol by pharmacodynamic antagonism. Use Caution/Monitor.brompheniraminebrompheniramine increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.bumetanideformoterol and bumetanide both decrease serum potassium. Use Caution/Monitor.mometasone inhaled increases toxicity of bumetanide by Other (see comment). Use Caution/Monitor. Comment: Corticosteroids may increase hypokalemic effect of loop diuretics.buprenorphine buccalbuprenorphine buccal increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.ceritinibmometasone inhaled increases toxicity of ceritinib by Other (see comment). Use Caution/Monitor. Comment: Corticosteroids may increase hypoglycemic effects of ceritinib.butabarbitalbutabarbital increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.butalbitalbutalbital increases