of formoterol by pharmacodynamic antagonism. Use Caution/Monitor. celiprolol increases and formoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.ceritinibMonitor Closely (2)ceritinib and formoterol both increase QTc interval. Use Caution/Monitor. mometasone inhaled increases toxicity of ceritinib by Other (see comment). Use Caution/Monitor. Comment: Corticosteroids may increase hypoglycemic effects of ceritinib.chloral hydrateMonitor Closely (1)chloral hydrate increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.chlordiazepoxideMonitor Closely (1)chlordiazepoxide increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.chloroquineMinor (1)chloroquine increases toxicity of formoterol by QTc interval. Minor/Significance Unknown.chlorothiazideMonitor Closely (2)mometasone inhaled increases toxicity of chlorothiazide by Other (see comment). Use Caution/Monitor. Comment: Corticosteroids may increase hypokalemic effect of loop diuretics. formoterol and chlorothiazide both decrease serum potassium. Use Caution/Monitor.Minor (1)formoterol, chlorothiazide. Mechanism: pharmacodynamic synergism. Minor/Significance Unknown. Hypokalemia.chlorpheniramineMonitor Closely (1)chlorpheniramine increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.chlorpromazineMonitor Closely (1)chlorpromazine increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.Serious - Use Alternative (1)chlorpromazine and formoterol both increase QTc interval. Avoid or Use Alternate Drug.chlorthalidoneMonitor Closely (2)formoterol and chlorthalidone both decrease serum potassium. Use Caution/Monitor. mometasone inhaled increases toxicity of chlorthalidone by Other (see comment). Use Caution/Monitor. Comment: Corticosteroids may increase hypokalemic effect of loop diuretics.Minor (1)formoterol, chlorthalidone. Mechanism: pharmacodynamic synergism. Minor/Significance Unknown. Hypokalemia.choline magnesium trisalicylateMonitor Closely (1)choline magnesium trisalicylate increases and formoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor. .cinnarizineMonitor Closely (1)cinnarizine increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.ciprofloxacinMonitor Closely (1)mometasone inhaled and ciprofloxacin both increase Other (see comment). Use Caution/Monitor. Coadministration of quinolone antibiotics and corticosteroids may increase risk of tendon rupture.clarithromycinMonitor Closely (1)clarithromycin will increase the level or effect of mometasone inhaled by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Increases riak for systemic corticosteroid side effectsSerious - Use Alternative (1)clarithromycin and formoterol both increase QTc interval. Avoid or Use Alternate Drug.clemastineMonitor Closely (1)clemastine increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.clomipramineMonitor Closely (1)clomipramine increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.Serious - Use Alternative (2)clomipramine and formoterol both increase QTc interval. Avoid or Use Alternate Drug. clomipramine, formoterol. Other (see comment). Avoid or Use Alternate Drug. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron.clonazepamMonitor Closely (1)clonazepam increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.clorazepateMonitor Closely (1)clorazepate increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.clozapineMonitor Closely (1)clozapine increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.cobicistatMonitor Closely (1)cobicistat will increase the level or effect of mometasone inhaled by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Increases risk for systemic corticosteroid side effectscodeineMonitor Closely (1)codeine increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.corticorelinMonitor Closely (1)mometasone inhaled decreases effects of corticorelin by Other (see comment). Use Caution/Monitor. Comment: Corticosteroids may blunt plasma ACTH response to corticorelin.cyclizineMonitor Closely (1)cyclizine increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.cyclopenthiazideMonitor Closely (1)formoterol and cyclopenthiazide both decrease serum potassium. Use Caution/Monitor.Minor (1)formoterol, cyclopenthiazide. Mechanism: pharmacodynamic synergism. Minor/Significance Unknown. Hypokalemia.cyproheptadineMonitor Closely (1)cyproheptadine increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.darunavirMonitor Closely (1)darunavir increases levels of mometasone inhaled by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Potential for increased toxicity. Increased risk of Cushing's syndrome or adrenal suppression.dasatinibMonitor Closely (1)dasatinib and formoterol both increase QTc interval. Modify Therapy/Monitor Closely.deferasiroxMonitor Closely (1)mometasone inhaled increases toxicity of deferasirox by Other (see comment). Use Caution/Monitor. Comment: Corticosteroids increase risk of gastrointestinal ulceration/irritation.deflazacortMonitor Closely (1)formoterol and deflazacort both decrease serum potassium. Use Caution/Monitor.degarelixMonitor Closely (1)degarelix and formoterol both increase QTc interval. Use Caution/Monitor.desipramineMonitor Closely (1)desipramine increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.Serious - Use Alternative (2)desipramine and formoterol both increase QTc interval. Avoid or Use Alternate Drug. desipramine, formoterol. Other (see comment). Avoid or Use Alternate Drug. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron.desmopressinSerious - Use Alternative (1)mometasone inhaled increases toxicity of desmopressin by Other (see comment). Avoid or Use Alternate Drug. Comment: Corticosteroids may enhance the hyponatremic effect of intranasal desmopressin.dexchlorpheniramineMonitor Closely (1)dexchlorpheniramine increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.dexfenfluramineMonitor Closely (2)formoterol and dexfenfluramine both decrease sedation. Use Caution/Monitor. formoterol and dexfenfluramine both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.dexmedetomidineMonitor Closely (1)dexmedetomidine increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.dexmethylphenidateMonitor Closely (2)formoterol and dexmethylphenidate both decrease sedation. Use Caution/Monitor. formoterol and dexmethylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.dextroamphetamineMonitor Closely (2)formoterol and dextroamphetamine both decrease sedation. Use Caution/Monitor. formoterol and dextroamphetamine both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.dextromoramideMonitor Closely (1)dextromoramide increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.diamorphineMonitor Closely (1)diamorphine increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.dichlorphenamideMonitor Closely (2)dichlorphenamide and formoterol both decrease serum potassium. Use Caution/Monitor. dichlorphenamide, formoterol. Either increases toxicity of the other by pharmacodynamic synergism. Modify Therapy/Monitor Closely. Both drugs can cause metabolic acidosis.diclofenacMonitor Closely (1)diclofenac increases and formoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.diethylpropionMonitor Closely (2)formoterol and diethylpropion both decrease sedation. Use Caution/Monitor. formoterol and diethylpropion both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.difenoxin hclMonitor Closely (1)difenoxin hcl increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.diflunisalMonitor Closely (1)diflunisal increases and formoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.digoxinMonitor Closely (1)digoxin increases and formoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.dimenhydrinateMonitor Closely (1)dimenhydrinate increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.diphenhydramineMonitor Closely (1)diphenhydramine increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.diphenoxylate hclMonitor Closely (1)diphenoxylate hcl increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.dipipanoneMonitor Closely (1)dipipanone increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.disopyramideSerious - Use Alternative (1)disopyramide and formoterol both increase QTc interval. Avoid or Use Alternate Drug.dobutamineMonitor Closely (3)dobutamine and formoterol both decrease serum potassium. Use Caution/Monitor. dobutamine and formoterol both decrease sedation. Use Caution/Monitor. dobutamine and formoterol both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.dofetilideSerious - Use Alternative (1)dofetilide and formoterol both increase QTc interval. Avoid or Use Alternate Drug.dolasetronMonitor Closely (1)dolasetron and formoterol both increase QTc interval. Modify Therapy/Monitor Closely.donepezilMonitor Closely (1)donepezil and formoterol both increase QTc interval. Use Caution/Monitor.dopamineMonitor Closely (2)formoterol and dopamine both decrease sedation. Use Caution/Monitor. formoterol and dopamine both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.dopexamineMonitor Closely (4)dopexamine, formoterol. Either increases effects of the other by pharmacodynamic synergism. Use Caution/Monitor. dopexamine and formoterol both decrease serum potassium. Use Caution/Monitor. dopexamine and formoterol both decrease sedation. Use Caution/Monitor. dopexamine and formoterol both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.doxepinMonitor Closely (1)doxepin increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.Serious - Use Alternative (2)doxepin and formoterol both increase QTc interval. Avoid or Use Alternate Drug. doxepin, formoterol. Other (see comment). Avoid or Use Alternate Drug. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron.dronedaroneSerious - Use Alternative (1)dronedarone and formoterol both increase QTc interval. Avoid or Use Alternate Drug.droperidolMonitor Closely (1)droperidol increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.Serious - Use Alternative (1)droperidol and formoterol both increase QTc interval. Avoid or Use Alternate Drug.drospirenoneMonitor Closely (1)drospirenone increases and formoterol decreases serum potassium. Effect of interaction is not clear, use caution. Modify Therapy/Monitor Closely.efavirenzMonitor Closely (1)efavirenz and formoterol both increase QTc interval. Use Caution/Monitor.elvitegravir/cobicistat/emtricitabine/tenofovir DFMonitor Closely (1)elvitegravir/cobicistat/emtricitabine/tenofovir DF will increase the level or effect of mometasone inhaled by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Increases riak for systemic corticosteroid side effectsencorafenibMonitor Closely (1)encorafenib and formoterol both increase QTc interval. Use Caution/Monitor.entrectinibSerious - Use Alternative (1)formoterol and entrectinib both increase QTc interval. Avoid or Use Alternate Drug.ephedrineMonitor Closely (3)ephedrine and formoterol both decrease serum potassium. Use Caution/Monitor. ephedrine and formoterol both decrease sedation. Use Caution/Monitor. ephedrine and formoterol both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.epinephrineMonitor Closely (3)epinephrine and formoterol both decrease serum potassium. Use Caution/Monitor. epinephrine and formoterol both decrease sedation. Use Caution/Monitor. epinephrine and formoterol both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.Serious - Use Alternative (1)epinephrine and formoterol both increase QTc interval. Avoid or Use Alternate Drug.epinephrine racemicMonitor Closely (3)formoterol and epinephrine racemic both decrease serum potassium. Use Caution/Monitor. formoterol and epinephrine racemic both decrease sedation. Use Caution/Monitor. formoterol and epinephrine racemic both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.Serious - Use Alternative (1)epinephrine racemic and formoterol both increase QTc interval. Avoid or Use Alternate Drug.eribulinMonitor Closely (1)eribulin and formoterol both increase QTc interval. Use Caution/Monitor.erythromycin baseSerious - Use Alternative (1)erythromycin base and formoterol both increase QTc interval. Avoid or Use Alternate Drug.erythromycin ethylsuccinateSerious - Use Alternative (1)erythromycin ethylsuccinate and formoterol both increase QTc interval. Avoid or Use Alternate Drug.erythromycin lactobionateSerious - Use Alternative (1)erythromycin lactobionate and formoterol both increase QTc interval. Avoid or Use Alternate Drug.erythromycin stearateSerious - Use Alternative (1)erythromycin stearate and formoterol both increase QTc interval. Avoid or Use Alternate Drug.escitalopramMonitor Closely (1)escitalopram increases toxicity of formoterol by QTc interval. Use Caution/Monitor.esmololMonitor Closely (2)esmolol decreases effects of formoterol by pharmacodynamic antagonism. Use Caution/Monitor. esmolol increases and formoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.estazolamMonitor Closely (1)estazolam increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.ethacrynic acidMonitor Closely (2)formoterol and ethacrynic acid both decrease serum potassium. Use Caution/Monitor. mometasone inhaled increases toxicity of ethacrynic acid by Other (see comment). Use Caution/Monitor. Comment: Corticosteroids may increase hypokalemic effect of loop diuretics.Minor (1)formoterol, ethacrynic acid. Mechanism: pharmacodynamic synergism. Minor/Significance Unknown. Hypokalemia.ethanolMonitor Closely (1)ethanol increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.etodolacMonitor Closely (1)etodolac increases and formoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.eucalyptusMinor (1)eucalyptus increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.fenfluramineMonitor Closely (2)formoterol and fenfluramine both decrease sedation. Use Caution/Monitor. formoterol and fenfluramine both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.fenoprofenMonitor Closely (1)fenoprofen increases and formoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.fexinidazoleSerious - Use Alternative (1)fexinidazole and formoterol both increase QTc interval. Avoid or Use Alternate Drug. Avoid coadministration of fexinidazole with drugs known to block potassium channels or prolong QT interval.fingolimodMonitor Closely (1)fingolimod and formoterol both increase QTc interval. Use Caution/Monitor.flecainideMonitor Closely (1)flecainide and formoterol both increase QTc interval. Modify Therapy/Monitor Closely.fluconazoleSerious - Use Alternative (1)fluconazole and formoterol both increase QTc interval. Avoid or Use Alternate Drug.fluoxetineMonitor Closely (1)fluoxetine and formoterol both increase QTc interval. Modify Therapy/Monitor Closely. Fluoxetine prolongs the QT interval; the prescribing information for fluoxetine recommends avoiding concurrent use of other drugs that may prolong the QT interval; risk may be increased with higher doses and/or when associated with hypokalemia; drugs that prolong the QTc interval may potentiate the effects of beta2 agonists on the cardiovascular systemfluphenazineMonitor Closely (1)fluphenazine increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.Serious - Use Alternative (1)fluphenazine and formoterol both increase QTc interval. Avoid or Use Alternate Drug.flurazepamMonitor Closely (1)flurazepam increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.flurbiprofenMonitor Closely (1)flurbiprofen increases