Use Caution/Monitor.ziconotideziconotide increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.ziprasidoneziprasidone increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.ziprasidone increases effects of ipratropium by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.albuterol and ziprasidone both increase QTc interval. Use Caution/Monitor.ipratropium decreases levels of ziprasidone by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.ipratropium decreases levels of ziprasidone by pharmacodynamic antagonism. Use Caution/Monitor.zotepineipratropium decreases levels of zotepine by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.ipratropium decreases levels of zotepine by pharmacodynamic antagonism. Use Caution/Monitor.Minor (15)bendroflumethiazidealbuterol, bendroflumethiazide. Mechanism: pharmacodynamic synergism. Minor/Significance Unknown. Hypokalemia.bumetanidealbuterol, bumetanide. Mechanism: pharmacodynamic synergism. Minor/Significance Unknown. Hypokalemia.chlorothiazidealbuterol, chlorothiazide. Mechanism: pharmacodynamic synergism. Minor/Significance Unknown. Hypokalemia.chlorthalidonealbuterol, chlorthalidone. Mechanism: pharmacodynamic synergism. Minor/Significance Unknown. Hypokalemia.cyclopenthiazidealbuterol, cyclopenthiazide. Mechanism: pharmacodynamic synergism. Minor/Significance Unknown. Hypokalemia.dimenhydrinatedimenhydrinate increases toxicity of ipratropium by pharmacodynamic synergism. Minor/Significance Unknown. Additive anticholinergic effects.donepezildonepezil decreases effects of ipratropium by pharmacodynamic antagonism. Minor/Significance Unknown.ethacrynic acidalbuterol, ethacrynic acid. Mechanism: pharmacodynamic synergism. Minor/Significance Unknown. Hypokalemia.eucalyptuseucalyptus increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.furosemidealbuterol, furosemide. Mechanism: pharmacodynamic synergism. Minor/Significance Unknown. Hypokalemia.galantaminegalantamine decreases effects of ipratropium by pharmacodynamic antagonism. Minor/Significance Unknown.hydrochlorothiazidealbuterol, hydrochlorothiazide. Mechanism: pharmacodynamic synergism. Minor/Significance Unknown. Hypokalemia.indapamidealbuterol, indapamide. Mechanism: pharmacodynamic synergism. Minor/Significance Unknown. Hypokalemia.levodopaipratropium, levodopa. Other (see comment). Minor/Significance Unknown. Comment: Anticholinergic agents may enhance the therapeutic effects of levodopa; however, anticholinergic agents can exacerbate tardive dyskinesia. In high dosage, anticholinergics may decrease the effects of levodopa by delaying its GI absorption. .methyclothiazidealbuterol, methyclothiazide. Mechanism: pharmacodynamic synergism. Minor/Significance Unknown. Hypokalemia.abobotulinumtoxinAMonitor Closely (1)abobotulinumtoxinA increases effects of ipratropium by pharmacodynamic synergism. Use Caution/Monitor. Use of anticholinergic drugs after administration of botulinum toxin-containing products may potentiate systemic anticholinergic effects. .acebutololMonitor Closely (2)acebutolol decreases effects of albuterol by pharmacodynamic antagonism. Use Caution/Monitor. acebutolol increases and albuterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.aceclofenacMonitor Closely (1)aceclofenac increases and albuterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.acemetacinMonitor Closely (1)acemetacin increases and albuterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.aclidiniumMonitor Closely (1)ipratropium and aclidinium both decrease cholinergic effects/transmission. Use Caution/Monitor.alfentanilMonitor Closely (1)alfentanil increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.alprazolamMonitor Closely (1)alprazolam increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.amantadineMonitor Closely (1)ipratropium, amantadine. Mechanism: pharmacodynamic synergism. Use Caution/Monitor. Potential for increased anticholinergic adverse effects.amilorideMonitor Closely (1)amiloride increases and albuterol decreases serum potassium. Effect of interaction is not clear, use caution. Modify Therapy/Monitor Closely.amiodaroneMonitor Closely (1)albuterol and amiodarone both increase QTc interval. Use Caution/Monitor.amisulprideMonitor Closely (2)amisulpride and albuterol both increase QTc interval. Use Caution/Monitor. ECG monitoring is recommended if coadministered. albuterol and amisulpride both increase QTc interval. Use Caution/Monitor.amitriptylineMonitor Closely (3)albuterol and amitriptyline both increase QTc interval. Use Caution/Monitor. ipratropium and amitriptyline both decrease cholinergic effects/transmission. Use Caution/Monitor. Due to the poor systemic absorption of ipratropium, interaction unlikely at regularly recommended dosages. amitriptyline increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.Serious - Use Alternative (1)amitriptyline, albuterol. Other (see comment). Avoid or Use Alternate Drug. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron.amobarbitalMonitor Closely (1)amobarbital increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.amoxapineMonitor Closely (2)ipratropium and amoxapine both decrease cholinergic effects/transmission. Use Caution/Monitor. Due to the poor systemic absorption of ipratropium, interaction unlikely at regularly recommended dosages. amoxapine increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.Serious - Use Alternative (1)amoxapine, albuterol. Other (see comment). Avoid or Use Alternate Drug. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron.anagrelideMonitor Closely (1)albuterol and anagrelide both increase QTc interval. Use Caution/Monitor.anticholinergic/sedative combosMonitor Closely (1)anticholinergic/sedative combos and ipratropium both decrease cholinergic effects/transmission. Use Caution/Monitor.apomorphineMonitor Closely (1)albuterol and apomorphine both increase QTc interval. Use Caution/Monitor.arformoterolMonitor Closely (3)albuterol and arformoterol both decrease serum potassium. Use Caution/Monitor. albuterol and arformoterol both decrease sedation. Use Caution/Monitor. albuterol and arformoterol both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.aripiprazoleMonitor Closely (4)ipratropium decreases levels of aripiprazole by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor. aripiprazole increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor. ipratropium decreases levels of aripiprazole by pharmacodynamic antagonism. Use Caution/Monitor. aripiprazole increases effects of ipratropium by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.armodafinilMonitor Closely (1)albuterol and armodafinil both decrease sedation. Use Caution/Monitor.arsenic trioxideMonitor Closely (1)albuterol and arsenic trioxide both increase QTc interval. Use Caution/Monitor.artemether/lumefantrineMonitor Closely (1)albuterol and artemether/lumefantrine both increase QTc interval. Use Caution/Monitor.asenapineMonitor Closely (1)albuterol and asenapine both increase QTc interval. Use Caution/Monitor.asenapine transdermalMonitor Closely (1)asenapine transdermal and albuterol both increase QTc interval. Use Caution/Monitor.aspirinMonitor Closely (1)aspirin increases and albuterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.aspirin rectalMonitor Closely (1)aspirin rectal increases and albuterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor. .aspirin/citric acid/sodium bicarbonateMonitor Closely (1)aspirin/citric acid/sodium bicarbonate increases and albuterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.atenololMonitor Closely (2)atenolol decreases effects of albuterol by pharmacodynamic antagonism. Use Caution/Monitor. atenolol increases and albuterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.atomoxetineMonitor Closely (1)atomoxetine, albuterol. Either increases effects of the other by pharmacodynamic synergism. Use Caution/Monitor. Risk of tachycardia, increased blood pressure.atracuriumMonitor Closely (1)atracurium and ipratropium both decrease cholinergic effects/transmission. Use Caution/Monitor.atropineMonitor Closely (1)atropine and ipratropium both decrease cholinergic effects/transmission. Use Caution/Monitor. Due to the poor systemic absorption of ipratropium, interaction unlikely at regularly recommended dosages.atropine IV/IMMonitor Closely (1)atropine IV/IM and ipratropium both decrease cholinergic effects/transmission. Use Caution/Monitor.azelastineMonitor Closely (1)azelastine increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.azithromycinSerious - Use Alternative (1)albuterol and azithromycin both increase QTc interval. Avoid or Use Alternate Drug.bedaquilineMonitor Closely (1)albuterol and bedaquiline both increase QTc interval. Use Caution/Monitor.belladonna alkaloidsMonitor Closely (1)belladonna alkaloids and ipratropium both decrease cholinergic effects/transmission. Use Caution/Monitor. Due to the poor systemic absorption of ipratropium, interaction unlikely at regularly recommended dosages.belladonna and opiumMonitor Closely (2)ipratropium and belladonna and opium both decrease cholinergic effects/transmission. Use Caution/Monitor. belladonna and opium increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.bendroflumethiazideMonitor Closely (1)albuterol and bendroflumethiazide both decrease serum potassium. Use Caution/Monitor.Minor (1)albuterol, bendroflumethiazide. Mechanism: pharmacodynamic synergism. Minor/Significance Unknown. Hypokalemia.benperidolMonitor Closely (4)benperidol increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor. ipratropium decreases levels of benperidol by pharmacodynamic antagonism. Use Caution/Monitor. ipratropium decreases levels of benperidol by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor. benperidol increases effects of ipratropium by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.benzphetamineMonitor Closely (2)albuterol and benzphetamine both decrease sedation. Use Caution/Monitor. albuterol and benzphetamine both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.benztropineMonitor Closely (1)benztropine and ipratropium both decrease cholinergic effects/transmission. Use Caution/Monitor. Additive anticholinergic adverse effects may be seen with concurrent use. betaxololMonitor Closely (2)betaxolol decreases effects of albuterol by pharmacodynamic antagonism. Use Caution/Monitor. betaxolol increases and albuterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.bethanecholMonitor Closely (1)bethanechol increases and ipratropium decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.bisoprololMonitor Closely (2)bisoprolol decreases effects of albuterol by pharmacodynamic antagonism. Use Caution/Monitor. bisoprolol increases and albuterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.brompheniramineMonitor Closely (1)brompheniramine increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.bumetanideMonitor Closely (1)albuterol and bumetanide both decrease serum potassium. Use Caution/Monitor.Minor (1)albuterol, bumetanide. Mechanism: pharmacodynamic synergism. Minor/Significance Unknown. Hypokalemia.buprenorphineMonitor Closely (2)buprenorphine increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor. albuterol and buprenorphine both increase QTc interval. Use Caution/Monitor.buprenorphine buccalMonitor Closely (2)buprenorphine buccal and albuterol both increase QTc interval. Use Caution/Monitor. buprenorphine buccal increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.buprenorphine subdermal implantMonitor Closely (1)buprenorphine subdermal implant and albuterol both increase QTc interval. Use Caution/Monitor.buprenorphine transdermalMonitor Closely (1)buprenorphine transdermal and albuterol both increase QTc interval. Use Caution/Monitor.buprenorphine, long-acting injectionMonitor Closely (1)buprenorphine, long-acting injection and albuterol both increase QTc interval. Use Caution/Monitor.butabarbitalMonitor Closely (1)butabarbital increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.butalbitalMonitor Closely (1)butalbital increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.butorphanolMonitor Closely (1)butorphanol increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.caffeineMonitor Closely (1)albuterol and caffeine both decrease sedation. Use Caution/Monitor.carbacholMonitor Closely (1)carbachol increases and ipratropium decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.carbenoxoloneMonitor Closely (1)albuterol and carbenoxolone both decrease serum potassium. Use Caution/Monitor.carbinoxamineMonitor Closely (1)carbinoxamine increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.carvedilolMonitor Closely (2)carvedilol decreases effects of albuterol by pharmacodynamic antagonism. Use Caution/Monitor. carvedilol increases and albuterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.celecoxibMonitor Closely (1)celecoxib increases and albuterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.celiprololMonitor Closely (2)celiprolol decreases effects of albuterol by pharmacodynamic antagonism. Use Caution/Monitor. celiprolol increases and albuterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.cevimelineMonitor Closely (1)cevimeline increases and ipratropium decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.chloral hydrateMonitor Closely (1)chloral hydrate increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.chlordiazepoxideMonitor Closely (1)chlordiazepoxide increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.chloroquineMonitor Closely (1)albuterol and chloroquine both increase QTc interval. Use Caution/Monitor.chlorothiazideMonitor Closely (1)albuterol and chlorothiazide both decrease serum potassium. Use Caution/Monitor.Minor (1)albuterol, chlorothiazide. Mechanism: pharmacodynamic synergism. Minor/Significance Unknown. Hypokalemia.chlorpheniramineMonitor Closely (1)chlorpheniramine increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.chlorpromazineMonitor Closely (5)chlorpromazine increases effects of ipratropium by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia. ipratropium decreases levels of chlorpromazine by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor. chlorpromazine increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor. ipratropium decreases levels of chlorpromazine by pharmacodynamic antagonism. Use Caution/Monitor. albuterol and chlorpromazine both increase QTc interval. Use Caution/Monitor.chlorthalidoneMonitor Closely (1)albuterol and chlorthalidone both decrease serum potassium. Use Caution/Monitor.Minor (1)albuterol, chlorthalidone. Mechanism: pharmacodynamic synergism. Minor/Significance Unknown. Hypokalemia.choline magnesium trisalicylateMonitor Closely (1)choline magnesium trisalicylate increases and albuterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor. .cinnarizineMonitor Closely (1)cinnarizine increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.ciprofloxacinMonitor Closely (1)albuterol and ciprofloxacin both increase QTc interval. Use Caution/Monitor.cisaprideContraindicated (1)albuterol and cisapride both increase QTc interval. Contraindicated.cisatracuriumMonitor Closely (1)cisatracurium and ipratropium both decrease cholinergic effects/transmission. Use Caution/Monitor.citalopramMonitor Closely (1)albuterol and citalopram both increase QTc interval. Use Caution/Monitor.clarithromycinMonitor Closely (1)albuterol and clarithromycin both increase QTc interval. Use Caution/Monitor.clemastineMonitor Closely (1)clemastine increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.clomipramineMonitor Closely (2)clomipramine increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor. ipratropium and clomipramine both decrease cholinergic effects/transmission. Use Caution/Monitor. Due to the poor systemic absorption of ipratropium, interaction unlikely at regularly recommended dosages.Serious - Use Alternative (1)clomipramine, albuterol. Other (see comment). Avoid or Use Alternate Drug. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron.clonazepamMonitor Closely (1)clonazepam increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.clorazepateMonitor Closely (1)clorazepate increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.clozapineMonitor Closely (5)ipratropium decreases levels of clozapine by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor. ipratropium decreases levels of clozapine by pharmacodynamic antagonism. Use Caution/Monitor. albuterol and clozapine both increase QTc interval. Use Caution/Monitor. clozapine increases effects of ipratropium by pharmacodynamic