AdultPediatricDosage Forms & Strengths tablets 100 mg Overactive Bladder Indicated for dysuria, increased urinary frequency/incontinence, nocturia, suprapubic pain, urinary incontinence, urinary tract irritation, urinary urgency 100-200 mg PO q6-8hrDosage Forms & Strengths tablets 100 mg Dysuria, Urinary Frequency Indicated for dysuria, increased urinary frequency, nocturia, suprapubic pain, urinary incontinence, urinary tract irritation, urinary urgency <12 years: Not recommended; safety and efficacy not established ≥12 years: 100-200 mg PO q6-8hrInteraction CheckerEnter a drug name and flavoxateNo Results No Interactions Found Interactions FoundContraindicatedSerious - Use AlternativeSignificant - Monitor CloselyMinorAll Interactions Sort By: SeverityName Contraindicated (0)Serious - Use Alternative (2)pramlintidepramlintide, flavoxate. Either increases effects of the other by pharmacodynamic synergism. Contraindicated. Synergistic inhibition of GI motility.secretinflavoxate decreases effects of secretin by pharmacodynamic antagonism. Avoid or Use Alternate Drug. Concomitant use of anticholinergic drugs may cause a hyporesponse to stimulation testing with secretin. Discontinue anticholinergic drugs at least 5 half-lives before administering secretin.Monitor Closely (89)aclidiniumflavoxate and aclidinium both decrease cholinergic effects/transmission. Use Caution/Monitor.amantadineflavoxate, amantadine. Mechanism: pharmacodynamic synergism. Use Caution/Monitor. Potential for increased anticholinergic adverse effects.amitriptylineflavoxate and amitriptyline both decrease cholinergic effects/transmission. Modify Therapy/Monitor Closely.amoxapineflavoxate and amoxapine both decrease cholinergic effects/transmission. Use Caution/Monitor.anticholinergic/sedative combosanticholinergic/sedative combos and flavoxate both decrease cholinergic effects/transmission. Use Caution/Monitor.aripiprazoleflavoxate decreases levels of aripiprazole by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.flavoxate decreases levels of aripiprazole by pharmacodynamic antagonism. Use Caution/Monitor.aripiprazole increases effects of flavoxate by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.atracuriumatracurium and flavoxate both decrease cholinergic effects/transmission. Use Caution/Monitor.atropineatropine and flavoxate both decrease cholinergic effects/transmission. Use Caution/Monitor.atropine IV/IMatropine IV/IM and flavoxate both decrease cholinergic effects/transmission. Use Caution/Monitor.belladonna alkaloidsbelladonna alkaloids and flavoxate both decrease cholinergic effects/transmission. Use Caution/Monitor.belladonna and opiumflavoxate and belladonna and opium both decrease cholinergic effects/transmission. Use Caution/Monitor.benperidolflavoxate decreases levels of benperidol by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.flavoxate decreases levels of benperidol by pharmacodynamic antagonism. Use Caution/Monitor.benperidol increases effects of flavoxate by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.benztropinebenztropine and flavoxate both decrease cholinergic effects/transmission. Use Caution/Monitor. Additive anticholinergic adverse effects may be seen with concurrent use. bethanecholbethanechol increases and flavoxate decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.carbacholcarbachol increases and flavoxate decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.cevimelinecevimeline increases and flavoxate decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.chlorpromazineflavoxate decreases levels of chlorpromazine by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.flavoxate decreases levels of chlorpromazine by pharmacodynamic antagonism. Use Caution/Monitor.chlorpromazine increases effects of flavoxate by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.cisatracuriumcisatracurium and flavoxate both decrease cholinergic effects/transmission. Use Caution/Monitor.clomipramineflavoxate and clomipramine both decrease cholinergic effects/transmission. Use Caution/Monitor.clozapineflavoxate decreases levels of clozapine by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.flavoxate decreases levels of clozapine by pharmacodynamic antagonism. Use Caution/Monitor.clozapine increases effects of flavoxate by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.cyclizinecyclizine and flavoxate both decrease cholinergic effects/transmission. Use Caution/Monitor.cyclobenzaprinecyclobenzaprine and flavoxate both decrease cholinergic effects/transmission. Use Caution/Monitor.darifenacindarifenacin and flavoxate both decrease cholinergic effects/transmission. Use Caution/Monitor.dicyclominedicyclomine and flavoxate both decrease cholinergic effects/transmission. Use Caution/Monitor.diphenhydraminediphenhydramine and flavoxate both decrease cholinergic effects/transmission. Use Caution/Monitor.donepezildonepezil increases and flavoxate decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.donepezil transdermaldonepezil transdermal, flavoxate. Either decreases effects of the other by pharmacodynamic antagonism. Use Caution/Monitor.dosulepinflavoxate and dosulepin both decrease cholinergic effects/transmission. Use Caution/Monitor.doxepinflavoxate and doxepin both decrease cholinergic effects/transmission. Use Caution/Monitor.droperidolflavoxate decreases levels of droperidol by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.flavoxate decreases levels of droperidol by pharmacodynamic antagonism. Use Caution/Monitor.droperidol increases effects of flavoxate by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.echothiophate iodideechothiophate iodide increases and flavoxate decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.fesoterodinefesoterodine and flavoxate both decrease cholinergic effects/transmission. Use Caution/Monitor.fluphenazineflavoxate decreases levels of fluphenazine by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.flavoxate decreases levels of fluphenazine by pharmacodynamic antagonism. Use Caution/Monitor.fluphenazine increases effects of flavoxate by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.galantaminegalantamine increases and flavoxate decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.glycopyrrolateflavoxate and glycopyrrolate both decrease cholinergic effects/transmission. Use Caution/Monitor.glycopyrrolate inhaledflavoxate and glycopyrrolate inhaled both decrease cholinergic effects/transmission. Use Caution/Monitor.haloperidolflavoxate decreases levels of haloperidol by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.flavoxate decreases levels of haloperidol by pharmacodynamic antagonism. Use Caution/Monitor.haloperidol increases effects of flavoxate by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.henbaneflavoxate and henbane both decrease cholinergic effects/transmission. Use Caution/Monitor.homatropineflavoxate and homatropine both decrease cholinergic effects/transmission. Use Caution/Monitor.huperzine Ahuperzine A increases and flavoxate decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.hyoscyamineflavoxate and hyoscyamine both decrease cholinergic effects/transmission. Use Caution/Monitor.hyoscyamine sprayflavoxate and hyoscyamine spray both decrease cholinergic effects/transmission. Use Caution/Monitor.iloperidoneflavoxate decreases levels of iloperidone by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.flavoxate decreases levels of iloperidone by pharmacodynamic antagonism. Use Caution/Monitor.iloperidone increases effects of flavoxate by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.imipramineflavoxate and imipramine both decrease cholinergic effects/transmission. Use Caution/Monitor.ipratropiumflavoxate and ipratropium both decrease cholinergic effects/transmission. Use Caution/Monitor. Due to the poor systemic absorption of ipratropium, interaction unlikely at regularly recommended dosages.lofepramineflavoxate and lofepramine both decrease cholinergic effects/transmission. Use Caution/Monitor.loxapineflavoxate decreases levels of loxapine by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.flavoxate decreases levels of loxapine by pharmacodynamic antagonism. Use Caution/Monitor.loxapine increases effects of flavoxate by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.loxapine inhaledloxapine inhaled increases effects of flavoxate by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.flavoxate decreases levels of loxapine inhaled by pharmacodynamic antagonism. Use Caution/Monitor.maprotilineflavoxate and maprotiline both decrease cholinergic effects/transmission. Use Caution/Monitor.meclizineflavoxate and meclizine both decrease cholinergic effects/transmission. Use Caution/Monitor.methscopolamineflavoxate and methscopolamine both decrease cholinergic effects/transmission. Use Caution/Monitor.neostigmineneostigmine increases and flavoxate decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.nortriptylineflavoxate and nortriptyline both decrease cholinergic effects/transmission. Use Caution/Monitor.olanzapineflavoxate decreases levels of olanzapine by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.flavoxate decreases levels of olanzapine by pharmacodynamic antagonism. Use Caution/Monitor.olanzapine increases effects of flavoxate by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.onabotulinumtoxinAonabotulinumtoxinA and flavoxate both decrease cholinergic effects/transmission. Use Caution/Monitor.orphenadrineflavoxate and orphenadrine both decrease cholinergic effects/transmission. Use Caution/Monitor.oxybutyninflavoxate and oxybutynin both decrease cholinergic effects/transmission. Use Caution/Monitor.oxybutynin topicalflavoxate and oxybutynin topical both decrease cholinergic effects/transmission. Use Caution/Monitor.oxybutynin transdermalflavoxate and oxybutynin transdermal both decrease cholinergic effects/transmission. Use Caution/Monitor.paliperidoneflavoxate decreases levels of paliperidone by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.flavoxate decreases levels of paliperidone by pharmacodynamic antagonism. Use Caution/Monitor.paliperidone increases effects of flavoxate by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.pancuroniumflavoxate and pancuronium both decrease cholinergic effects/transmission. Use Caution/Monitor.perphenazineflavoxate decreases levels of perphenazine by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.flavoxate decreases levels of perphenazine by pharmacodynamic antagonism. Use Caution/Monitor.perphenazine increases effects of flavoxate by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.physostigminephysostigmine increases and flavoxate decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.pilocarpinepilocarpine increases and flavoxate decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.pimozideflavoxate decreases levels of pimozide by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.flavoxate decreases levels of pimozide by pharmacodynamic antagonism. Use Caution/Monitor.pimozide increases effects of flavoxate by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.pralidoximeflavoxate and pralidoxime both decrease cholinergic effects/transmission. Use Caution/Monitor.prochlorperazineflavoxate decreases levels of prochlorperazine by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.flavoxate decreases levels of prochlorperazine by pharmacodynamic antagonism. Use Caution/Monitor.prochlorperazine increases effects of flavoxate by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.promethazineflavoxate decreases levels of promethazine by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.flavoxate decreases levels of promethazine by pharmacodynamic antagonism. Use Caution/Monitor.promethazine increases effects of flavoxate by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.propanthelineflavoxate and propantheline both decrease cholinergic effects/transmission. Use Caution/Monitor.protriptylineflavoxate and protriptyline both decrease cholinergic effects/transmission. Use Caution/Monitor.pyridostigminepyridostigmine increases and flavoxate decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.quetiapineflavoxate decreases levels of quetiapine by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.flavoxate decreases levels of quetiapine by pharmacodynamic antagonism. Use Caution/Monitor.quetiapine increases effects of flavoxate by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.rapacuroniumflavoxate and rapacuronium both decrease cholinergic effects/transmission. Use Caution/Monitor.risperidoneflavoxate decreases levels of risperidone by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.flavoxate decreases levels of risperidone by pharmacodynamic antagonism. Use Caution/Monitor.risperidone increases effects of flavoxate by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.rocuroniumflavoxate and rocuronium both decrease cholinergic effects/transmission. Use Caution/Monitor.scopolamineflavoxate and scopolamine both decrease cholinergic effects/transmission. Use Caution/Monitor.solifenacinflavoxate and solifenacin both decrease cholinergic effects/transmission. Use Caution/Monitor.succinylcholinesuccinylcholine increases and flavoxate decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor.thioridazineflavoxate decreases levels of thioridazine by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.flavoxate decreases levels of thioridazine by pharmacodynamic antagonism. Use Caution/Monitor.thioridazine increases effects of flavoxate by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.thiothixeneflavoxate decreases levels of thiothixene by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.flavoxate decreases levels of thiothixene by pharmacodynamic antagonism. Use Caution/Monitor.thiothixene increases effects of flavoxate by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.tiotropiumflavoxate and tiotropium both decrease cholinergic effects/transmission. Use Caution/Monitor.tolterodineflavoxate and tolterodine both decrease cholinergic effects/transmission. Use Caution/Monitor.trifluoperazineflavoxate decreases levels of trifluoperazine by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.flavoxate decreases levels of trifluoperazine by pharmacodynamic antagonism. Use Caution/Monitor.trifluoperazine increases effects of flavoxate by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.trihexyphenidylflavoxate and trihexyphenidyl both decrease cholinergic effects/transmission. Use Caution/Monitor. Potential for additive anticholinergic effects.trimipramineflavoxate and trimipramine both decrease cholinergic effects/transmission. Use Caution/Monitor.trospium chlorideflavoxate and trospium chloride both decrease cholinergic effects/transmission. Use Caution/Monitor.vecuroniumflavoxate and vecuronium both decrease cholinergic effects/transmission. Use Caution/Monitor.ziprasidoneflavoxate decreases levels of ziprasidone by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.flavoxate decreases levels of ziprasidone by pharmacodynamic antagonism. Use Caution/Monitor.ziprasidone increases effects of flavoxate by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.zotepineflavoxate decreases levels of zotepine by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.flavoxate decreases levels of zotepine by pharmacodynamic antagonism. Use Caution/Monitor.Minor (8)atenololflavoxate increases effects of atenolol by unspecified interaction mechanism. Minor/Significance Unknown.desipramineflavoxate and desipramine both decrease cholinergic effects/transmission. Minor/Significance Unknown.digoxinflavoxate increases effects of digoxin by unspecified interaction mechanism. Minor/Significance Unknown.dimenhydrinatedimenhydrinate increases toxicity of flavoxate by pharmacodynamic synergism. Minor/Significance Unknown. Additive anticholinergic effects.donepezildonepezil decreases effects of flavoxate by pharmacodynamic antagonism. Minor/Significance Unknown.galantaminegalantamine decreases effects of flavoxate by pharmacodynamic antagonism. Minor/Significance Unknown.levodopaflavoxate, levodopa. Other (see comment). Minor/Significance Unknown. Comment: Anticholinergic agents may enhance the therapeutic effects of levodopa; however, anticholinergic agents can exacerbate tardive dyskinesia. In high dosage, anticholinergics may decrease the effects of levodopa by delaying its GI absorption. .trazodoneflavoxate and trazodone both decrease cholinergic effects/transmission. Minor/Significance Unknown.aclidiniumMonitor Closely (1)flavoxate and aclidinium both decrease cholinergic effects/transmission. Use Caution/Monitor.amantadineMonitor Closely (1)flavoxate, amantadine. Mechanism: pharmacodynamic synergism. Use Caution/Monitor. Potential for increased anticholinergic adverse effects.amitriptylineMonitor Closely (1)flavoxate and amitriptyline both decrease cholinergic effects/transmission. Modify Therapy/Monitor Closely.amoxapineMonitor Closely (1)flavoxate and amoxapine both decrease cholinergic effects/transmission. Use Caution/Monitor.anticholinergic/sedative combosMonitor Closely (1)anticholinergic/sedative combos and flavoxate both decrease cholinergic effects/transmission. Use Caution/Monitor.aripiprazoleMonitor Closely (3)flavoxate decreases levels of aripiprazole by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor. flavoxate decreases levels of aripiprazole by pharmacodynamic antagonism. Use Caution/Monitor. aripiprazole increases effects of flavoxate by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.atenololMinor (1)flavoxate increases effects of atenolol by unspecified interaction mechanism. Minor/Significance Unknown.atracuriumMonitor Closely (1)atracurium and flavoxate both decrease cholinergic effects/transmission. Use Caution/Monitor.atropineMonitor Closely (1)atropine and flavoxate both decrease cholinergic effects/transmission. Use Caution/Monitor.atropine IV/IMMonitor Closely (1)atropine IV/IM and flavoxate both decrease cholinergic effects/transmission. Use Caution/Monitor.belladonna alkaloidsMonitor Closely (1)belladonna alkaloids and flavoxate both decrease cholinergic effects/transmission. Use Caution/Monitor.belladonna and opiumMonitor Closely (1)flavoxate and belladonna and opium