pharmacodynamic synergism. Minor/Significance Unknown. Interaction especially seen in the treatment of hypokalemia.rosiglitazonepotassium citrate increases effects of rosiglitazone by pharmacodynamic synergism. Minor/Significance Unknown. Interaction especially seen in the treatment of hypokalemia.saxagliptinpotassium citrate increases effects of saxagliptin by pharmacodynamic synergism. Minor/Significance Unknown. Interaction especially seen in the treatment of hypokalemia.sitagliptinpotassium citrate increases effects of sitagliptin by pharmacodynamic synergism. Minor/Significance Unknown. Interaction especially seen in the treatment of hypokalemia.tolazamidepotassium citrate increases effects of tolazamide by pharmacodynamic synergism. Minor/Significance Unknown. Interaction especially seen in the treatment of hypokalemia.tolbutamidepotassium citrate increases effects of tolbutamide by pharmacodynamic synergism. Minor/Significance Unknown. Interaction especially seen in the treatment of hypokalemia.acarboseMinor (1)potassium citrate increases effects of acarbose by pharmacodynamic synergism. Minor/Significance Unknown. Interaction especially seen in the treatment of hypokalemia.acebutololMonitor Closely (1)acebutolol and potassium citrate both increase serum potassium. Use Caution/Monitor.amantadineMonitor Closely (1)potassium citrate will increase the level or effect of amantadine by Other (see comment). Modify Therapy/Monitor Closely. Urine pH changes towards alkalinic conditions may lead to an accumulation of amantadine with a possible increase in adverse reactions. Monitor for adverse reactions of amantadine.amilorideMonitor Closely (1)amiloride and potassium citrate both increase serum potassium. Use Caution/Monitor.amphotericin B deoxycholateMinor (1)amphotericin B deoxycholate decreases levels of potassium citrate by increasing renal clearance. Minor/Significance Unknown.arformoterolMonitor Closely (1)potassium citrate increases and arformoterol decreases serum potassium. Effect of interaction is not clear, use caution. Modify Therapy/Monitor Closely.aspirinMonitor Closely (1)aspirin and potassium citrate both increase serum potassium. Use Caution/Monitor.aspirin rectalMonitor Closely (1)aspirin rectal and potassium citrate both increase serum potassium. Use Caution/Monitor.aspirin/citric acid/sodium bicarbonateMonitor Closely (1)aspirin/citric acid/sodium bicarbonate and potassium citrate both increase serum potassium. Use Caution/Monitor.atenololMonitor Closely (1)atenolol and potassium citrate both increase serum potassium. Use Caution/Monitor.benazeprilMonitor Closely (2)potassium citrate and benazepril both increase serum potassium. Use Caution/Monitor. Potassium salts may increase the hyperkalemic effects of ACE inhibitors; the effect may be the result of aldosterone suppression in patients receiving ACE inhibitors benazepril increases levels of potassium citrate by decreasing elimination. Use Caution/Monitor. Risk of hyperkalemia.betaxololMonitor Closely (1)betaxolol and potassium citrate both increase serum potassium. Use Caution/Monitor.bisacodylMonitor Closely (1)bisacodyl decreases levels of potassium citrate by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.bisoprololMonitor Closely (1)bisoprolol and potassium citrate both increase serum potassium. Use Caution/Monitor.bumetanideMonitor Closely (1)potassium citrate increases and bumetanide decreases serum potassium. Effect of interaction is not clear, use caution. Modify Therapy/Monitor Closely.cadexomer iodineMinor (1)cadexomer iodine increases levels of potassium citrate by decreasing renal clearance. Minor/Significance Unknown. Hyperkalemia.canagliflozinMonitor Closely (1)potassium citrate and canagliflozin both increase serum potassium. Use Caution/Monitor.candesartanMonitor Closely (1)candesartan and potassium citrate both increase serum potassium. Use Caution/Monitor.captoprilMonitor Closely (1)captopril increases levels of potassium citrate by decreasing elimination. Use Caution/Monitor. Risk of hyperkalemia.carvedilolMonitor Closely (1)carvedilol and potassium citrate both increase serum potassium. Modify Therapy/Monitor Closely.celecoxibMonitor Closely (1)celecoxib and potassium citrate both increase serum potassium. Modify Therapy/Monitor Closely.chlorothiazideMonitor Closely (1)potassium citrate increases and chlorothiazide decreases serum potassium. Effect of interaction is not clear, use caution. Modify Therapy/Monitor Closely.chlorpropamideMinor (1)potassium citrate increases effects of chlorpropamide by pharmacodynamic synergism. Minor/Significance Unknown. Interaction especially seen in the treatment of hypokalemia.chlorthalidoneMonitor Closely (1)potassium citrate increases and chlorthalidone decreases serum potassium. Effect of interaction is not clear, use caution. Modify Therapy/Monitor Closely.choline magnesium trisalicylateMonitor Closely (1)choline magnesium trisalicylate and potassium citrate both increase serum potassium. Modify Therapy/Monitor Closely.cyclopenthiazideMonitor Closely (1)potassium citrate increases and cyclopenthiazide decreases serum potassium. Effect of interaction is not clear, use caution. Modify Therapy/Monitor Closely.cyclosporineMonitor Closely (1)cyclosporine and potassium citrate both increase serum potassium. Use Caution/Monitor.dextroamphetamine transdermalSerious - Use Alternative (1)potassium citrate will increase the level or effect of dextroamphetamine transdermal by Other (see comment). Avoid or Use Alternate Drug. Urinary alkalinizing agents can increase blood levels and potentiate the action of amphetamine.diclofenacMonitor Closely (1)diclofenac and potassium citrate both increase serum potassium. Modify Therapy/Monitor Closely.diflunisalMonitor Closely (1)diflunisal and potassium citrate both increase serum potassium. Modify Therapy/Monitor Closely.disopyramideMonitor Closely (1)potassium citrate increases effects of disopyramide by pharmacodynamic synergism. Use Caution/Monitor. Additive cardiovascular depression.dobutamineMonitor Closely (1)potassium citrate increases and dobutamine decreases serum potassium. Effect of interaction is not clear, use caution. Modify Therapy/Monitor Closely.drospirenoneSerious - Use Alternative (1)drospirenone and potassium citrate both increase serum potassium. Avoid or Use Alternate Drug.enalaprilMonitor Closely (1)enalapril increases levels of potassium citrate by decreasing elimination. Use Caution/Monitor. Risk of hyperkalemia.ephedrineMonitor Closely (1)potassium citrate increases and ephedrine decreases serum potassium. Effect of interaction is not clear, use caution. Modify Therapy/Monitor Closely.epinephrineMonitor Closely (1)potassium citrate increases and epinephrine decreases serum potassium. Effect of interaction is not clear, use caution. Modify Therapy/Monitor Closely.epinephrine racemicMonitor Closely (1)potassium citrate increases and epinephrine racemic decreases serum potassium. Effect of interaction is not clear, use caution. Modify Therapy/Monitor Closely.eplerenoneMonitor Closely (1)potassium citrate and eplerenone both increase serum potassium. Modify Therapy/Monitor Closely.eprosartanMonitor Closely (1)eprosartan and potassium citrate both increase serum potassium. Use Caution/Monitor.esmololMonitor Closely (1)esmolol and potassium citrate both increase serum potassium. Modify Therapy/Monitor Closely.ethacrynic acidMonitor Closely (1)potassium citrate increases and ethacrynic acid decreases serum potassium. Effect of interaction is not clear, use caution. Modify Therapy/Monitor Closely.etodolacMonitor Closely (1)etodolac and potassium citrate both increase serum potassium. Modify Therapy/Monitor Closely.fenoprofenMonitor Closely (1)fenoprofen and potassium citrate both increase serum potassium. Modify Therapy/Monitor Closely.finerenoneMonitor Closely (1)potassium citrate and finerenone both increase serum potassium. Modify Therapy/Monitor Closely. Finerenone dose adjustment based on current serum potassium concentration. Monitor serum potassium and adjust finerenone dose as described in the prescribing information as necessary.flurbiprofenMonitor Closely (1)flurbiprofen and potassium citrate both increase serum potassium. Modify Therapy/Monitor Closely.formoterolMonitor Closely (1)potassium citrate increases and formoterol decreases serum potassium. Effect of interaction is not clear, use caution. Modify Therapy/Monitor Closely.fosinoprilMonitor Closely (1)fosinopril increases levels of potassium citrate by decreasing elimination. Use Caution/Monitor. Risk of hyperkalemia.furosemideMonitor Closely (1)potassium citrate increases and furosemide decreases serum potassium. Effect of interaction is not clear, use caution. Modify Therapy/Monitor Closely.gentamicinMonitor Closely (1)potassium citrate increases and gentamicin decreases serum potassium. Effect of interaction is not clear, use caution. Modify Therapy/Monitor Closely.glimepirideMinor (1)potassium citrate increases effects of glimepiride by pharmacodynamic synergism. Minor/Significance Unknown. Interaction especially seen in the treatment of hypokalemia.glipizideMinor (1)potassium citrate increases effects of glipizide by pharmacodynamic synergism. Minor/Significance Unknown. Interaction especially seen in the treatment of hypokalemia.glyburideMinor (1)potassium citrate increases effects of glyburide by pharmacodynamic synergism. Minor/Significance Unknown. Interaction especially seen in the treatment of hypokalemia.hydrochlorothiazideMonitor Closely (1)potassium citrate increases and hydrochlorothiazide decreases serum potassium. Effect of interaction is not clear, use caution. Modify Therapy/Monitor Closely.ibuprofenMonitor Closely (1)ibuprofen and potassium citrate both increase serum potassium. Modify Therapy/Monitor Closely.ibuprofen IVMonitor Closely (1)ibuprofen IV and potassium citrate both increase serum potassium. Modify Therapy/Monitor Closely.indapamideMonitor Closely (1)potassium citrate increases and indapamide decreases serum potassium. Effect of interaction is not clear, use caution. Modify Therapy/Monitor Closely.indomethacinMonitor Closely (1)indomethacin and potassium citrate both increase serum potassium. Modify Therapy/Monitor Closely.insulin aspartMinor (1)potassium citrate increases effects of insulin aspart by pharmacodynamic synergism. Minor/Significance Unknown. Interaction especially seen in the treatment of hypokalemia.insulin detemirMinor (1)potassium citrate increases effects of insulin detemir by pharmacodynamic synergism. Minor/Significance Unknown. Interaction especially seen in the treatment of hypokalemia.insulin glargineMinor (1)potassium citrate increases effects of insulin glargine by pharmacodynamic synergism. Minor/Significance Unknown. Interaction especially seen in the treatment of hypokalemia.insulin glulisineMinor (1)potassium citrate increases effects of insulin glulisine by pharmacodynamic synergism. Minor/Significance Unknown. Interaction especially seen in the treatment of hypokalemia.insulin lisproMinor (1)potassium citrate increases effects of insulin lispro by pharmacodynamic synergism. Minor/Significance Unknown. Interaction especially seen in the treatment of hypokalemia.insulin NPHMinor (1)potassium citrate increases effects of insulin NPH by pharmacodynamic synergism. Minor/Significance Unknown. Interaction especially seen in the treatment of hypokalemia.insulin regular humanMinor (1)potassium citrate increases effects of insulin regular human by pharmacodynamic synergism. Minor/Significance Unknown. Interaction especially seen in the treatment of hypokalemia.iodinated glycerolMinor (1)iodinated glycerol increases levels of potassium citrate by decreasing renal clearance. Minor/Significance Unknown. Hyperkalemia.iodineMinor (1)iodine increases levels of potassium citrate by decreasing renal clearance. Minor/Significance Unknown. Hyperkalemia.irbesartanMonitor Closely (1)irbesartan and potassium citrate both increase serum potassium. Use Caution/Monitor.isoproterenolMonitor Closely (1)potassium citrate increases and isoproterenol decreases serum potassium. Effect of interaction is not clear, use caution. Modify Therapy/Monitor Closely.ketoprofenMonitor Closely (1)ketoprofen and potassium citrate both increase serum potassium. Modify Therapy/Monitor Closely.ketorolacMonitor Closely (1)ketorolac and potassium citrate both increase serum potassium. Modify Therapy/Monitor Closely.labetalolMonitor Closely (1)labetalol and potassium citrate both increase serum potassium. Modify Therapy/Monitor Closely.levalbuterolMonitor Closely (1)potassium citrate increases and levalbuterol decreases serum potassium. Effect of interaction is not clear, use caution. Modify Therapy/Monitor Closely.lisinoprilMonitor Closely (1)lisinopril increases levels of potassium citrate by decreasing elimination. Use Caution/Monitor. Risk of hyperkalemia.losartanMonitor Closely (1)losartan and potassium citrate both increase serum potassium. Use Caution/Monitor.meclofenamateMonitor Closely (1)meclofenamate and potassium citrate both increase serum potassium. Modify Therapy/Monitor Closely.mefenamic acidMonitor Closely (1)mefenamic acid and potassium citrate both increase serum potassium. Modify Therapy/Monitor Closely.meloxicamMonitor Closely (1)meloxicam and potassium citrate both increase serum potassium. Modify Therapy/Monitor Closely.metaproterenolMonitor Closely (1)potassium citrate increases and metaproterenol decreases serum potassium. Effect of interaction is not clear, use caution. Modify Therapy/Monitor Closely.metforminMinor (1)potassium citrate increases effects of metformin by pharmacodynamic synergism. Minor/Significance Unknown. Interaction especially seen in the treatment of hypokalemia.methyclothiazideMonitor Closely (1)potassium citrate increases and methyclothiazide decreases serum potassium. Effect of interaction is not clear, use caution. Modify Therapy/Monitor Closely. .metolazoneMonitor Closely (1)potassium citrate increases and metolazone decreases serum potassium. Effect of interaction is not clear, use caution. Modify Therapy/Monitor Closely.metoprololMonitor Closely (1)metoprolol and potassium citrate both increase serum potassium. Modify Therapy/Monitor Closely.miglitolMinor (1)potassium citrate increases effects of miglitol by pharmacodynamic synergism. Minor/Significance Unknown. Interaction especially seen in the treatment of hypokalemia.moexiprilMonitor Closely (1)moexipril increases levels of potassium citrate by decreasing elimination. Use Caution/Monitor. Risk of hyperkalemia.nabumetoneMonitor Closely (1)nabumetone and potassium citrate both increase serum potassium. Modify Therapy/Monitor Closely.nadololMonitor Closely (1)nadolol and potassium citrate both increase serum potassium. Modify Therapy/Monitor Closely.naproxenMonitor Closely (1)naproxen and potassium citrate both increase serum potassium. Modify Therapy/Monitor Closely.nateglinideMinor (1)potassium citrate increases effects of nateglinide by pharmacodynamic synergism. Minor/Significance Unknown. Interaction especially seen in the treatment of hypokalemia.nebivololMonitor Closely (1)nebivolol and potassium citrate both increase serum potassium. Modify Therapy/Monitor Closely.noni juiceMonitor Closely (1)potassium citrate and noni juice both increase serum potassium. Use Caution/Monitor.norepinephrineMonitor Closely (1)potassium citrate increases and norepinephrine decreases serum potassium. Effect of interaction is not clear, use caution. Modify Therapy/Monitor Closely.olmesartanMonitor Closely (1)olmesartan and potassium citrate both increase serum potassium. Use Caution/Monitor.oxaprozinMonitor Closely (1)oxaprozin and potassium citrate both increase serum potassium. Modify Therapy/Monitor Closely.penbutololMonitor Closely (1)penbutolol and potassium citrate both increase serum potassium. Modify Therapy/Monitor Closely.perindoprilMonitor Closely (1)perindopril increases levels of potassium citrate by decreasing elimination. Use Caution/Monitor. Risk of hyperkalemia.pindololMonitor Closely (1)pindolol and potassium citrate both increase serum potassium. Modify Therapy/Monitor Closely.pioglitazoneMinor (1)potassium citrate increases effects of pioglitazone by pharmacodynamic synergism. Minor/Significance Unknown. Interaction especially seen in the treatment of hypokalemia.pirbuterolMonitor Closely (1)potassium citrate increases and pirbuterol decreases serum potassium. Effect of interaction is not clear, use caution. Modify Therapy/Monitor Closely.piroxicamMonitor Closely (1)piroxicam and potassium citrate both increase serum potassium. Modify Therapy/Monitor Closely.potassium acid phosphateSerious - Use Alternative (1)potassium acid phosphate and potassium citrate both increase serum potassium. Avoid or Use Alternate Drug.potassium chlorideSerious - Use Alternative (1)potassium chloride and potassium citrate both increase serum potassium. Avoid or Use Alternate Drug.potassium citrate/citric acidMonitor Closely (1)potassium citrate and potassium citrate/citric acid both increase serum potassium. Use Caution/Monitor.potassium iodideMonitor Closely (1)potassium iodide and potassium citrate both increase serum potassium. Use Caution/Monitor.potassium phosphates, IVSerious - Use Alternative (1)potassium citrate and potassium phosphates, IV both increase serum potassium. Avoid or Use Alternate Drug.propranololMonitor Closely (1)propranolol and potassium citrate both increase serum potassium. Modify Therapy/Monitor Closely.quinaprilMonitor Closely (1)quinapril increases levels of potassium citrate by decreasing elimination. Use Caution/Monitor. Risk of hyperkalemia.ramiprilMonitor Closely (1)ramipril increases levels of potassium citrate by decreasing elimination. Use Caution/Monitor. Risk of hyperkalemia.repaglinideMinor (1)potassium citrate increases effects of repaglinide by pharmacodynamic synergism. Minor/Significance Unknown. Interaction especially seen in the treatment of hypokalemia.rosiglitazoneMinor (1)potassium citrate increases effects of rosiglitazone by pharmacodynamic synergism. Minor/Significance Unknown. Interaction especially seen in the treatment of hypokalemia.sacubitril/valsartanMonitor Closely (1)sacubitril/valsartan and potassium citrate both increase serum potassium. Use Caution/Monitor.salicylates (non-asa)Monitor Closely (1)salicylates (non-asa) and potassium citrate both increase serum potassium. Modify Therapy/Monitor Closely.salmeterolMonitor Closely (1)potassium citrate increases and salmeterol decreases serum potassium. Effect of interaction is not clear, use caution. Modify Therapy/Monitor Closely.salsalateMonitor Closely (1)salsalate and potassium citrate both increase serum potassium. Modify Therapy/Monitor Closely.saxagliptinMinor (1)potassium citrate increases effects of saxagliptin by pharmacodynamic synergism. Minor/Significance Unknown. Interaction especially seen in the treatment of hypokalemia.sitagliptinMinor (1)potassium citrate increases effects of sitagliptin by pharmacodynamic synergism. Minor/Significance Unknown. Interaction especially seen in the treatment of hypokalemia.sotalolMonitor Closely (1)sotalol and potassium citrate both increase serum potassium. Modify Therapy/Monitor Closely.sparsentanMonitor Closely (1)sparsentan and potassium citrate both increase serotonin levels. Use Caution/Monitor. Monitor