methamphetamine both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.methyclothiazidearformoterol and methyclothiazide both decrease serum potassium. Use Caution/Monitor.methylenedioxymethamphetaminearformoterol and methylenedioxymethamphetamine both decrease sedation. Use Caution/Monitor.arformoterol and methylenedioxymethamphetamine both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.methylphenidatearformoterol and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.metolazonearformoterol and metolazone both decrease serum potassium. Use Caution/Monitor.metoprololmetoprolol increases and arformoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.metoprolol decreases effects of arformoterol by pharmacodynamic antagonism. Use Caution/Monitor.midazolammidazolam increases and arformoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.midodrinearformoterol and midodrine both decrease sedation. Use Caution/Monitor.arformoterol and midodrine both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.midostaurinarformoterol and midostaurin both increase QTc interval. Use Caution/Monitor.mifepristonemifepristone, arformoterol. QTc interval. Modify Therapy/Monitor Closely. Use alternatives if available.mirtazapinemirtazapine increases and arformoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.arformoterol and mirtazapine both increase QTc interval. Use Caution/Monitor.modafinilarformoterol and modafinil both decrease sedation. Use Caution/Monitor.morphinemorphine increases and arformoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.motherwortmotherwort increases and arformoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.moxifloxacinarformoterol and moxifloxacin both increase QTc interval. Use Caution/Monitor.moxonidinemoxonidine increases and arformoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.nabilonenabilone increases and arformoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.nabumetonenabumetone increases and arformoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.nadololnadolol increases and arformoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.nadolol decreases effects of arformoterol by pharmacodynamic antagonism. Use Caution/Monitor.nalbuphinenalbuphine increases and arformoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.naproxennaproxen increases and arformoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.nebivololnebivolol increases and arformoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.nebivolol decreases effects of arformoterol by pharmacodynamic antagonism. Use Caution/Monitor.nilotinibarformoterol and nilotinib both increase QTc interval. Use Caution/Monitor.norepinephrinearformoterol and norepinephrine both decrease serum potassium. Use Caution/Monitor.arformoterol and norepinephrine both decrease sedation. Use Caution/Monitor.arformoterol and norepinephrine both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.nortriptylinenortriptyline increases and arformoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.arformoterol and nortriptyline both increase QTc interval. Use Caution/Monitor.octreotidearformoterol and octreotide both increase QTc interval. Use Caution/Monitor.ofloxacinarformoterol and ofloxacin both increase QTc interval. Use Caution/Monitor.olanzapineolanzapine increases and arformoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.arformoterol and olanzapine both increase QTc interval. Use Caution/Monitor. Limited data, including some case reports, suggest that olanzapine may be associated with a significant prolongation of the QTc interval in rare instancesolodaterol inhaledarformoterol and olodaterol inhaled both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor. Caution with coadministration of adrenergic drugs by any route because of additive sympathetic effectsarformoterol and olodaterol inhaled both increase QTc interval. Use Caution/Monitor.opium tinctureopium tincture increases and arformoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.osilodrostatosilodrostat and arformoterol both increase QTc interval. Use Caution/Monitor.osimertinibosimertinib and arformoterol both increase QTc interval. Use Caution/Monitor. Conduct periodic monitoring with ECGs and electrolytes in patients taking drugs known to prolong the QTc interval.oxaliplatinoxaliplatin will increase the level or effect of arformoterol by Other (see comment). Use Caution/Monitor. Monitor for ECG changes if therapy is initiated in patients with drugs known to prolong QT interval.arformoterol and oxaliplatin both increase QTc interval. Use Caution/Monitor.oxaprozinoxaprozin increases and arformoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.oxazepamoxazepam increases and arformoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.oxycodoneoxycodone increases and arformoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.oxymorphoneoxymorphone increases and arformoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.ozanimodozanimod and arformoterol both increase QTc interval. Modify Therapy/Monitor Closely. The potential additive effects on heart rate, treatment with ozanimod should generally not be initiated in patients who are concurrently treated with QT prolonging drugs with known arrhythmogenic properties.paliperidonepaliperidone increases and arformoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.arformoterol and paliperidone both increase QTc interval. Use Caution/Monitor.papaveretumpapaveretum increases and arformoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.papaverinepapaverine increases and arformoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.parecoxibparecoxib increases and arformoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.pasireotidearformoterol and pasireotide both increase QTc interval. Modify Therapy/Monitor Closely.pazopanibarformoterol and pazopanib both increase QTc interval. Use Caution/Monitor.penbutololpenbutolol increases and arformoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.penbutolol decreases effects of arformoterol by pharmacodynamic antagonism. Use Caution/Monitor.pentazocinepentazocine increases and arformoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.pentobarbitalpentobarbital increases and arformoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.perphenazineperphenazine increases and arformoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.arformoterol and perphenazine both increase QTc interval. Use Caution/Monitor.phendimetrazinearformoterol and phendimetrazine both decrease sedation. Use Caution/Monitor.arformoterol and phendimetrazine both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.phenobarbitalphenobarbital increases and arformoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.phenoxybenzaminephenoxybenzamine, arformoterol. Mechanism: pharmacodynamic synergism. Use Caution/Monitor. Hypotension, tachycardia.phenterminearformoterol and phentermine both decrease sedation. Use Caution/Monitor.arformoterol and phentermine both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.phenylephrinearformoterol and phenylephrine both decrease sedation. Use Caution/Monitor.arformoterol and phenylephrine both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.phenylephrine POarformoterol and phenylephrine PO both decrease sedation. Use Caution/Monitor.arformoterol and phenylephrine PO both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.pholcodinepholcodine increases and arformoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.pimavanserinarformoterol and pimavanserin both increase QTc interval. Use Caution/Monitor.pimozidepimozide increases and arformoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.pindololpindolol increases and arformoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.pindolol decreases effects of arformoterol by pharmacodynamic antagonism. Use Caution/Monitor.pirbuterolarformoterol and pirbuterol both decrease serum potassium. Use Caution/Monitor.arformoterol and pirbuterol both decrease sedation. Use Caution/Monitor.arformoterol and pirbuterol both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.piroxicampiroxicam increases and arformoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.pitolisantarformoterol and pitolisant both increase QTc interval. Use Caution/Monitor.ponesimodarformoterol and ponesimod both increase QTc interval. Use Caution/Monitor.posaconazolearformoterol and posaconazole both increase QTc interval. Use Caution/Monitor.potassium acid phosphatepotassium acid phosphate increases and arformoterol decreases serum potassium. Effect of interaction is not clear, use caution. Modify Therapy/Monitor Closely.potassium chloridepotassium chloride increases and arformoterol decreases serum potassium. Effect of interaction is not clear, use caution. Modify Therapy/Monitor Closely.potassium citratepotassium citrate increases and arformoterol decreases serum potassium. Effect of interaction is not clear, use caution. Modify Therapy/Monitor Closely.primaquinearformoterol and primaquine both increase QTc interval. Use Caution/Monitor.primidoneprimidone increases and arformoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.procainamidearformoterol and procainamide both increase QTc interval. Use Caution/Monitor.procarbazineprocarbazine increases effects of arformoterol by pharmacodynamic synergism. Use Caution/Monitor. Risk of acute hypertensive episode.prochlorperazineprochlorperazine increases and arformoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.promethazinepromethazine increases and arformoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.propafenonearformoterol and propafenone both increase QTc interval. Use Caution/Monitor.propranololpropranolol increases and arformoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.propranolol decreases effects of arformoterol by pharmacodynamic antagonism. Use Caution/Monitor.propylhexedrinearformoterol and propylhexedrine both decrease sedation. Use Caution/Monitor.arformoterol and propylhexedrine both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.protriptylineprotriptyline increases and arformoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.arformoterol and protriptyline both increase QTc interval. Use Caution/Monitor.pseudoephedrinearformoterol and pseudoephedrine both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.quazepamquazepam increases and arformoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.quetiapinequetiapine increases and arformoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.arformoterol and quetiapine both increase QTc interval. Use Caution/Monitor.quinidinearformoterol and quinidine both increase QTc interval. Use Caution/Monitor.quininearformoterol and quinine both increase QTc interval. Use Caution/Monitor.ranolazinearformoterol and ranolazine both increase QTc interval. Use Caution/Monitor.ribociclibribociclib increases toxicity of arformoterol by QTc interval. Use Caution/Monitor.rilpivirinearformoterol and rilpivirine both increase QTc interval. Use Caution/Monitor.risperidonerisperidone increases and arformoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.arformoterol and risperidone both increase QTc interval. Use Caution/Monitor.romidepsinarformoterol and romidepsin both increase QTc interval. Use Caution/Monitor.sacubitril/valsartansacubitril/valsartan increases and arformoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.salicylates (non-asa)salicylates (non-asa) increases and arformoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.salmeterolarformoterol and salmeterol both decrease serum potassium. Use Caution/Monitor.arformoterol and salmeterol both decrease sedation. Use Caution/Monitor.arformoterol and salmeterol both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.salsalatesalsalate increases and arformoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.saquinavirarformoterol and saquinavir both increase QTc interval. Use Caution/Monitor.scullcapscullcap increases and arformoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.secobarbitalsecobarbital increases and arformoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.selpercatinibselpercatinib increases toxicity of arformoterol by QTc interval. Use Caution/Monitor.serdexmethylphenidate/dexmethylphenidatearformoterol and serdexmethylphenidate/dexmethylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.sertralinearformoterol and sertraline both increase QTc interval. Use Caution/Monitor.sevofluranearformoterol and sevoflurane both increase QTc interval. Use Caution/Monitor.shepherd's purseshepherd's purse increases and arformoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.siponimodarformoterol and siponimod both increase QTc interval. Use Caution/Monitor.sodium sulfate/potassium chloride/magnesium sulfate/polyethylene glycolarformoterol and sodium sulfate/potassium chloride/magnesium sulfate/polyethylene glycol both decrease serum potassium. Modify Therapy/Monitor Closely.solifenacinarformoterol and solifenacin both increase QTc interval. Use Caution/Monitor.solriamfetolarformoterol and solriamfetol both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.sorafenibsorafenib and arformoterol both increase QTc interval. Use Caution/Monitor.sotalolsotalol increases and arformoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.sotalol decreases effects of arformoterol by pharmacodynamic antagonism. Use Caution/Monitor.arformoterol and sotalol both increase QTc interval. Use Caution/Monitor.spironolactonespironolactone increases and arformoterol decreases serum potassium. Effect of interaction is not clear, use caution. Modify Therapy/Monitor Closely.succinylcholinesuccinylcholine increases and arformoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.sufentanilsufentanil increases and arformoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.sulfasalazinesulfasalazine increases and arformoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.sulindacsulindac increases and arformoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.sunitinibarformoterol and sunitinib both increase QTc interval. Use Caution/Monitor.tacrolimusarformoterol and tacrolimus both increase QTc interval. Use Caution/Monitor.tapentadoltapentadol increases and arformoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.telavancinarformoterol and telavancin both increase QTc interval. Use Caution/Monitor.temazepamtemazepam increases and arformoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.terbutalinearformoterol and terbutaline both decrease serum potassium. Use Caution/Monitor.arformoterol and terbutaline both decrease sedation. Use Caution/Monitor.arformoterol and terbutaline both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.tetrabenazinearformoterol and tetrabenazine both increase QTc interval. Use Caution/Monitor.thioridazinethioridazine increases and arformoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.thiothixenethiothixene increases and arformoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.timololtimolol increases and arformoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.timolol decreases effects of arformoterol by pharmacodynamic antagonism. Use Caution/Monitor.tolfenamic acidtolfenamic acid increases and arformoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.tolmetintolmetin increases and arformoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.tolvaptantolvaptan increases and arformoterol decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor.topiramatetopiramate increases and arformoterol decreases sedation. Effect of interaction is not clear, use caution. Modify Therapy/Monitor Closely.toremifenearformoterol and toremifene both increase QTc interval. Use Caution/Monitor.torsemidearformoterol and torsemide both decrease serum potassium. Use Caution/Monitor.tramadoltramadol increases and arformoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.trazodonetrazodone increases and