AdultPediatricGeriatricDosage Forms & Strengths capsule 1mg 2mg 5mg 10mg Benign Prostate Hyperplasia Initial: 1 mg PO qHS May gradually increase to 5 mg PO qHS; up to 20 mg/day beneficial for some Dosing considerations Give first dose and subsequent increases at bedtime to avoid syncope May take with food Hypertension Initial: 1 mg PO qHS Maintenance: 1-5 mg/day or q12hr; may increase to ≤20 mg/day Dosing considerations Give first dose and subsequent increases at bedtime to avoid syncope May take with food Dosing Modifications Hepatic impairment: Use with cautionDosage Forms & Strengths capsule 1mg 2mg 5mg 10mg Hypertension (Off-label) 1 mg/day PO; increase dose gradually as necessary; up to maximum of 20 mg/dayHypertension Initial: 0.5 mg PO qHS and titrate to response Dosing considerations Avoid use for hypertension; high risk of orthostatic hypotension (Beers criteria) May cause significant orthostatic hypotension and syncope Lower initial doses than those used for nongeriatric adults, as well as gradual adjustments, are recommended for hypertension Give first dose and subsequent increases at bedtime to avoid syncope Adverse effects such as dry mouth and urinary complications can be bothersome in the elderly May take with foodInteraction CheckerEnter a drug name and terazosinNo Results No Interactions Found Interactions FoundContraindicatedSerious - Use AlternativeSignificant - Monitor CloselyMinorAll Interactions Sort By: SeverityName Contraindicated (0)Serious - Use Alternative (5)lofexidinelofexidine, terazosin. Either increases effects of the other by pharmacodynamic synergism. Avoid or Use Alternate Drug. Avoid coadministration with other drugs that decrease pulse or blood pressure to mitigate risk of excessive bradycardia and hypotension.sildenafilsildenafil increases effects of terazosin by pharmacodynamic synergism. Avoid or Use Alternate Drug. Risk of hypotension; separate sildenafil >25mg from alpha blocker by 4hr.tamsulosinterazosin, tamsulosin. Either increases effects of the other by additive vasodilation. Avoid or Use Alternate Drug. Risk of hypotension.vardenafilvardenafil increases effects of terazosin by pharmacodynamic synergism. Contraindicated. Risk of hypotension.yohimbeyohimbe increases effects of terazosin by pharmacodynamic synergism. Contraindicated.Monitor Closely (92)acebutololterazosin and acebutolol both increase anti-hypertensive channel blocking. Modify Therapy/Monitor Closely. Additive hypotensive effects may occur when terazosin is used in combination with acebutolol.aceclofenacaceclofenac decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.acemetacinacemetacin decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.aldesleukinaldesleukin increases effects of terazosin by pharmacodynamic synergism. Use Caution/Monitor. Risk of hypotension.alfuzosinalfuzosin and terazosin both increase anti-hypertensive channel blocking. Use Caution/Monitor.amifostineamifostine, terazosin. Either increases effects of the other by pharmacodynamic synergism. Modify Therapy/Monitor Closely. Coadministration with blood pressure lowering agents may increase the risk and severity of hypotension associated with amifostine. When amifostine is used at chemotherapeutic doses, withhold blood pressure lowering medications for 24 hr prior to amifostine; if blood pressure lowering medication cannot be withheld, do not administer amifostine.amlodipineterazosin and amlodipine both increase anti-hypertensive channel blocking. Use Caution/Monitor.asenapineasenapine and terazosin both increase anti-hypertensive channel blocking. Use Caution/Monitor.aspirinaspirin decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.aspirin rectalaspirin rectal decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.aspirin/citric acid/sodium bicarbonateaspirin/citric acid/sodium bicarbonate decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.atenololterazosin and atenolol both increase anti-hypertensive channel blocking. Modify Therapy/Monitor Closely.avanafilavanafil increases effects of terazosin by pharmacodynamic synergism. Use Caution/Monitor. Risk of hypotension.benazeprilbenazepril, terazosin. Either increases effects of the other by pharmacodynamic synergism. Use Caution/Monitor. Exaggerated first dose hypotensive response.betaxololterazosin and betaxolol both increase anti-hypertensive channel blocking. Modify Therapy/Monitor Closely.bisoprololterazosin and bisoprolol both increase anti-hypertensive channel blocking. Modify Therapy/Monitor Closely.bretyliumterazosin, bretylium. Either increases effects of the other by pharmacodynamic synergism. Modify Therapy/Monitor Closely. Each drug may cause hypotension.captoprilcaptopril, terazosin. Either increases effects of the other by Mechanism: pharmacodynamic synergism. Use Caution/Monitor. Exaggerated first dose hypotensive response. Both drugs lower blood pressure. Monitor blood pressure.carbidopacarbidopa increases effects of terazosin by pharmacodynamic synergism. Use Caution/Monitor. Therapy with carbidopa, given with or without levodopa or carbidopa-levodopa combination products, is started, dosage adjustment of the antihypertensive drug may be required.carvedilolterazosin and carvedilol both increase anti-hypertensive channel blocking. Modify Therapy/Monitor Closely.celecoxibcelecoxib decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.celiprololterazosin and celiprolol both increase anti-hypertensive channel blocking. Modify Therapy/Monitor Closely.choline magnesium trisalicylatecholine magnesium trisalicylate decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.clevidipineterazosin and clevidipine both increase anti-hypertensive channel blocking. Use Caution/Monitor.diclofenacdiclofenac decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.diflunisaldiflunisal decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.diltiazemterazosin and diltiazem both increase anti-hypertensive channel blocking. Use Caution/Monitor.doxazosindoxazosin and terazosin both increase anti-hypertensive channel blocking. Use Caution/Monitor.enalaprilenalapril, terazosin. Mechanism: pharmacodynamic synergism. Use Caution/Monitor. Exaggerated first dose hypotensive response.esmololterazosin and esmolol both increase anti-hypertensive channel blocking. Modify Therapy/Monitor Closely. Additive hypotensive effects may occur when terazosin is used in combination with esmolol.etodolacetodolac decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.felodipineterazosin and felodipine both increase anti-hypertensive channel blocking. Use Caution/Monitor.fenoprofenfenoprofen decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.flurbiprofenflurbiprofen decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.fosinoprilfosinopril, terazosin. Mechanism: pharmacodynamic synergism. Use Caution/Monitor. Exaggerated first dose hypotensive response.ibuprofenibuprofen decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.ibuprofen IVibuprofen IV decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.iloperidoneiloperidone increases effects of terazosin by pharmacodynamic synergism. Use Caution/Monitor.imidaprilimidapril, terazosin. Mechanism: pharmacodynamic synergism. Use Caution/Monitor. Exaggerated first dose hypotensive response.indomethacinindomethacin decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.isradipineterazosin and isradipine both increase anti-hypertensive channel blocking. Use Caution/Monitor.ketoprofenketoprofen decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.ketorolacketorolac decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.ketorolac intranasalketorolac intranasal decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.labetalolterazosin and labetalol both increase anti-hypertensive channel blocking. Modify Therapy/Monitor Closely.levodopalevodopa increases effects of terazosin by pharmacodynamic synergism. Use Caution/Monitor. Consider decreasing dosage of antihypertensive agent.lisinoprillisinopril, terazosin. Mechanism: pharmacodynamic synergism. Use Caution/Monitor. Exaggerated first dose hypotensive response.lornoxicamlornoxicam decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.lurasidonelurasidone increases effects of terazosin by Other (see comment). Use Caution/Monitor. Comment: Potential for increased risk of hypotension with concurrent use. Monitor blood pressure and adjust dose of antihypertensive agent as needed.maravirocmaraviroc, terazosin. Either increases effects of the other by pharmacodynamic synergism. Use Caution/Monitor. Increased risk of orthostatic hypotension.meclofenamatemeclofenamate decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.mefenamic acidmefenamic acid decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.meloxicammeloxicam decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.methylphenidatemethylphenidate will decrease the level or effect of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. Methylphenidate may diminish antihypertensive effects. Monitor BP.metoprololterazosin and metoprolol both increase anti-hypertensive channel blocking. Modify Therapy/Monitor Closely.moexiprilmoexipril, terazosin. Mechanism: pharmacodynamic synergism. Use Caution/Monitor. Exaggerated first dose hypotensive response.moxisylytemoxisylyte and terazosin both increase anti-hypertensive channel blocking. Use Caution/Monitor.nabumetonenabumetone decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.nadololterazosin and nadolol both increase anti-hypertensive channel blocking. Modify Therapy/Monitor Closely.naproxennaproxen decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.nebivololterazosin and nebivolol both increase anti-hypertensive channel blocking. Modify Therapy/Monitor Closely.nicardipineterazosin and nicardipine both increase anti-hypertensive channel blocking. Use Caution/Monitor.nifedipineterazosin and nifedipine both increase anti-hypertensive channel blocking. Use Caution/Monitor.nisoldipineterazosin and nisoldipine both increase anti-hypertensive channel blocking. Use Caution/Monitor.nitroglycerin rectalnitroglycerin rectal, terazosin. Either increases effects of the other by pharmacodynamic synergism. Use Caution/Monitor. Observe for possible additive hypotensive effects during concomitant use. .oxaprozinoxaprozin decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.oxymetazoline topicaloxymetazoline topical increases and terazosin decreases sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Effect of interaction is not clear, use caution. Use Caution/Monitor.parecoxibparecoxib decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.penbutololterazosin and penbutolol both increase anti-hypertensive channel blocking. Modify Therapy/Monitor Closely.perindoprilperindopril, terazosin. Mechanism: pharmacodynamic synergism. Use Caution/Monitor. Exaggerated first dose hypotensive response.phenoxybenzaminephenoxybenzamine and terazosin both increase anti-hypertensive channel blocking. Use Caution/Monitor.phentolaminephentolamine and terazosin both increase anti-hypertensive channel blocking. Use Caution/Monitor.pindololterazosin and pindolol both increase anti-hypertensive channel blocking. Modify Therapy/Monitor Closely.piroxicampiroxicam decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.prazosinprazosin and terazosin both increase anti-hypertensive channel blocking. Use Caution/Monitor.propranololterazosin and propranolol both increase anti-hypertensive channel blocking. Modify Therapy/Monitor Closely. Additive hypotensive effects may occur when terazosin is used in combination with propranolol.pseudoephedrinepseudoephedrine decreases effects of terazosin by sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.quinaprilquinapril, terazosin. Mechanism: pharmacodynamic synergism. Use Caution/Monitor. Exaggerated first dose hypotensive response.ramiprilramipril, terazosin. Mechanism: pharmacodynamic synergism. Use Caution/Monitor. Exaggerated first dose hypotensive response.salicylates (non-asa)salicylates (non-asa) decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.salsalatesalsalate decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.silodosinsilodosin and terazosin both increase anti-hypertensive channel blocking. Use Caution/Monitor.sotalolterazosin and sotalol both increase anti-hypertensive channel blocking. Modify Therapy/Monitor Closely. Additive hypotensive effects may occur when terazosin is used in combination with sotalol.sulfasalazinesulfasalazine decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.sulindacsulindac decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.tadalafiltadalafil increases effects of terazosin by pharmacodynamic synergism. Use Caution/Monitor. Risk of hypotension.timololterazosin and timolol both increase anti-hypertensive channel blocking. Modify Therapy/Monitor Closely.tolfenamic acidtolfenamic acid decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.tolmetintolmetin decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.trandolapriltrandolapril, terazosin. Mechanism: pharmacodynamic synergism. Use Caution/Monitor. Exaggerated first dose hypotensive response.verapamilterazosin and verapamil both increase anti-hypertensive channel blocking. Use Caution/Monitor.zotepineterazosin and zotepine both increase anti-hypertensive channel blocking. Use Caution/Monitor.Minor (7)brimonidinebrimonidine increases effects of terazosin by pharmacodynamic synergism. Minor/Significance Unknown.butcher's broomterazosin, butcher's broom. Either decreases effects of the other by Mechanism: pharmacodynamic antagonism. Minor/Significance Unknown.ethanolterazosin, ethanol. Mechanism: pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypotension, esp. in Asian pts.phenylephrineterazosin, phenylephrine. Either decreases effects of the other by Mechanism: pharmacodynamic antagonism. Minor/Significance Unknown.phenylephrine POterazosin, phenylephrine PO. Either decreases effects of the other by Mechanism: pharmacodynamic antagonism. Minor/Significance Unknown.tizanidinetizanidine increases effects of terazosin by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypotension.treprostiniltreprostinil increases effects of terazosin by pharmacodynamic synergism. Minor/Significance Unknown.acebutololMonitor Closely (1)terazosin and acebutolol both increase anti-hypertensive channel blocking. Modify Therapy/Monitor Closely. Additive hypotensive effects may occur when terazosin is used in combination with acebutolol.aceclofenacMonitor Closely (1)aceclofenac decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.acemetacinMonitor Closely (1)acemetacin decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.aldesleukinMonitor Closely (1)aldesleukin increases effects of terazosin by pharmacodynamic synergism. Use Caution/Monitor. Risk of hypotension.alfuzosinMonitor Closely (1)alfuzosin and terazosin both increase anti-hypertensive channel blocking. Use Caution/Monitor.amifostineMonitor Closely (1)amifostine, terazosin. Either increases effects of the other by pharmacodynamic synergism. Modify Therapy/Monitor Closely. Coadministration with blood pressure lowering agents may increase the risk and severity of hypotension associated with amifostine. When amifostine is used at chemotherapeutic doses, withhold blood pressure lowering medications for 24 hr prior to amifostine; if blood pressure lowering medication cannot be withheld, do not administer amifostine.amlodipineMonitor Closely (1)terazosin and amlodipine both increase anti-hypertensive channel blocking. Use Caution/Monitor.asenapineMonitor Closely (1)asenapine and terazosin both increase anti-hypertensive channel blocking. Use Caution/Monitor.aspirinMonitor Closely (1)aspirin decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.aspirin rectalMonitor Closely (1)aspirin rectal decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.aspirin/citric acid/sodium bicarbonateMonitor Closely (1)aspirin/citric acid/sodium bicarbonate decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.atenololMonitor Closely (1)terazosin and atenolol both increase anti-hypertensive channel blocking. Modify Therapy/Monitor Closely.avanafilMonitor Closely (1)avanafil increases effects of terazosin by pharmacodynamic synergism. Use Caution/Monitor. Risk of hypotension.benazeprilMonitor Closely (1)benazepril, terazosin. Either increases effects of the other by pharmacodynamic synergism. Use Caution/Monitor. Exaggerated first dose hypotensive response.betaxololMonitor Closely (1)terazosin and betaxolol both increase anti-hypertensive channel blocking. Modify Therapy/Monitor Closely.bisoprololMonitor Closely (1)terazosin and bisoprolol both increase anti-hypertensive channel blocking. Modify Therapy/Monitor Closely.bretyliumMonitor Closely (1)terazosin, bretylium. Either increases effects of the other by pharmacodynamic synergism. Modify Therapy/Monitor Closely. Each drug may cause hypotension.brimonidineMinor (1)brimonidine increases effects of terazosin by pharmacodynamic synergism. Minor/Significance Unknown.butcher's broomMinor (1)terazosin, butcher's broom. Either decreases effects of the other by Mechanism: pharmacodynamic antagonism. Minor/Significance Unknown.captoprilMonitor Closely (1)captopril, terazosin. Either increases effects of the other by Mechanism: pharmacodynamic synergism. Use Caution/Monitor. Exaggerated first dose hypotensive response. Both drugs lower blood pressure. Monitor blood pressure.carbidopaMonitor Closely (1)carbidopa increases effects of terazosin by pharmacodynamic synergism. Use Caution/Monitor. Therapy with carbidopa, given with or without levodopa