Gene therapy for color blindness
Research
Adult dichromat squirrel monkeys was converted into trichromats using gene therapy. New world monkeys such as squirrel monkeys lack the L-opsin gene and are incapable of discriminating between certain shades of red and green. Recombinant AAV vector was used to deliver a human L-opsin gene into the monkey’s retina. Cones that gained the missing genes began expressing the new photopigment.
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