[header] How to avoid constipation when taking temodar (temozolomide ) [title] Stay hydrated. [step] Drinking water (and other non-caffeinated liquids) is very important to avoid constipation. Unless your doctor told you to restrict your fluids, regularly drink 8-12 cups daily of fluids like water, decaf tea, warm lemonade, or prune juice. 
Water can also help flush out excess toxins from chemotherapy. [substeps] Aim to drink 2-3 quarts of fluid every 24 hours.