[header] How to soothe a sore and irritated nose after frequent blowing [title] Apply a soothing moisturizer to the outside of your nostrils. [step] Petroleum jellies like vaseline and ointments like neosporin work best. Place a small amount of the product on a q-tip, then apply it around the entrance of each nostril. 
The extra moisture will not only relieve dryness, but will also create a barrier against irritation from a runny nose. [substeps] If you don't have something like vaseline or neosporin handy, you can use your regular facial lotion.