[header] How to know when to stop breeding a female dog [title] Factor in the age of the dog. [step] There are a variety of opinions and standards as to when dogs should be retired from breeding. However, you should follow standards you are most comfortable with to protect the health of your dog. 
[substeps] Many kennel clubs require a dog to be 8 years or younger to register litters. Many vets suggest that dogs of normal health should be retired from breeding around 8 years old.