[header] How to diagnose motor neuron diseases [title] Notice a loss of muscle control in your legs. [step] The early symptoms of mnds involve weakening muscles and diminished muscle control. These symptoms typically begin in 1 of 3 areas: the legs, the hands and arms, or the mouth. 
Tripping, falling, or having trouble walking are often early signs of progressive mnds. Symptoms of a developing mnd also include having trouble putting weight on your legs and ankles.