Roddenberry was probably most known for her role as the voice of the computers in nearly every Star Trek television spinoff series from the 1960's to present time. She is also the voice of the computer in the upcoming movie by director J.J. Abrams, Star Trek. Majel also played Nurse Chapel in the original Star Trek series starring William Shatner and later played Lwaxana Troi in Star Trek: The Next Generation and Star Trek: Deep Space Nine.
Majel Roddenberry died of cancer.