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This project explores the idea that markers of cell stress and inflammation found within the blood can identify diabetic subjects at risk for the rapid development of chronic blood vessel complications such as nerve , eye and kidney disease . The majority of these toxic effects occur due to long term changes in genes . At present , when a corporate disclosure statement is not filed , courts do not know whether it has not been filed because there was nothing to report or because of ignorance of Rule 26.1 ( a ) . He is a third-generation graduate of the University of Michigan Medical School . Type 1 diabetes is an autoimmune disease resulting in the destruction of pancreatic beta cells with a loss of insulin within the blood . These contaminations ( often leading to the pollution of the ground water ) have resulted in a restriction of the utilization of these sites and , in some cases , a complete prohibition on cultivation .