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During the earlier part of her MERIT Award research , Dr. Dykstra found that the analgesic effects of morphine are determined in part by how the drug interacts with the mu receptor . The main analysis found that rear window defoggers have no effect on changing lane and backing crashes in conditions when they are most likely used ( when raining or snowing , during the earlier part of the morning , or during winter ) . They are most likely to be used if any one or more of the following occur : it is snowing or raining , during the earlier part of the morning or during winter . And if you could imagine a society , say during the earlier part of this country , in which there are very few government commons , there was no immigration issue .