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Starting in 1835 , Alfred Drake of Philadelphia developed an internal combustion engine over a 20-year period . This would most likely be prohibitively slow , so the project would also include developing some kind of static analysis to determine when no accesses to a location will be made after it is freed , in which case no dynamic information need be kept . He was preaching to the converted at the Peer-to-Peer conference , a gathering of technical and business folk who are looking to develop the file-sharing capabilities demonstrated by Napster , as well as other P2P apps , into profitable enterprises . Many agree that Windows NT will develop the robustness , seasoning and maturity required of an operating system for such applications . This year more than 300 industry insiders , influencers and leaders will once again gather in this industry-sponsored event to discuss how a changing marketplace will affect them and how they can develop the strategies to leverage change to their advantage . GTK + , TK and GNUstep licenses allow you to develop both open source and closed source applications without paying for a license . When the child was later readmitted for routine chemotherapy , she developed an infection and had to receive antibiotics intravenously ( IV ) through a tube inserted into the child 's veins - a peripherally inserted central catheter ( PICC ) . To identify novel surface proteins , we have developed a photoaffinity labeling approach using 125I-INA . I suppose someone has developed an index of global / diversity awareness that can be administered as an outcomes test but honestly how do we know that our graduates achieve the goals of understanding the non-universality of culture , religion and values or accept the responsibility for global citizenship ? It has developed an increasingly international membership in the last few years , particularly in the United Kingdom but also on the Continent and on the Pacific Rim . I want you to know that I believe too that our future is about revolutionizing the way we grow and develop the men and women who raise their right hand and take the oath to support this nation . We developed a hierarchical model for estimation of group attributes from a collection of estimates of population trend . This Government-wide competition resulted in a team that includes NASA Lewis Research Center 's Computer Services Division , who will develop the graphical user interface ( GUI ) and test it in their usability lab . For example , researchers have developed a number of techniques for providing reasonable trade-offs between the individual 's need for privacy and the society 's need to protect itself . Schug et al. developed a rule-based function prediction method based on the intersection of GO terms that contain protein domain at different similarity levels [ 16 ] . We developed a system for cell motion analysis in the magnetic field that allowed us to measure correlation between cell magnetophoretic mobility and cell surface antigen expression , when labeled with monoclonal antibodies and magnetic nanoparticles . First PennDOT developed an excellent training program , a training database , an award-winning ECMS , as well as excellent program manuals . Through an examination of ancient documents and artifacts , students will have the opportunity to develop both their research and analytical skills . All of a sudden , however , four enthusiastic students in the class huddled together in serious discussion , developing some sort of joint strategy .