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The main purpose of this study is to determine the safety and effectiveness of high-dose immunosuppressive therapy followed by re-infusion ( transplantation ) of the subject ’ s own autologous ( self ) peripheral blood stem cells ( PBSCs ) compared to treatment with monthly ( for 12 months ) intravenous doses of cyclophosphamide ( Cytoxan ) therapy for the treatment of severe systemic sclerosis ( SSc ) . Fellows are responsible for running a clinical unit that also consists of junior and senior house officers from the Core Internal Medicine program , fourth year medical students who have chosen a rotation in Rheumatology ( acting as sub-interns ) , and house officers from Orthopedics , Physical Medicine and Rehabilitation and sometimes other services who have chosen a month of Rheumatology training . Fellows are provided with membership of the American College of Rheumatology and are offered the opportunity to attend the ACR annual meeting as well as one additional meeting of their choice ; most choose the State-of-the-Art Clinical Symposium in Chicago . The best studied drug is the immune system suppressant agent known as cyclophosphamide ( Cytoxan ® ) . Speakers are drawn from Rheumatology faculty and faculty from other units and covers topics relevant to the entire clinical and basic science curriculum in a two year cycle . Two articles are usually presented , one basic science article by a postdoctoral research Fellow or Rheumatology Fellow in the research part of their training , and one clinically-based article , which is presented by a Rheumatology Fellow . Mr. Gord Mackintosh ( St. Johns ) : The government called this committee . He has served as the interim chariman of the Department of Biological Chemistry and was a member of the NIH Endocrinology Study . We participate in the American College of Rheumatology in-service examination and all our Fellows take this annually . " So writes Joseph Viteritti of New York University in the Yale Law & Policy Review .