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But nerves in the spinal cord , leading to and from the brain , were considered impossible to restore . Careers include designing , building and managing information systems , whether it is a technical role , leading teams on large software projects , or a managerial role with responsibility for computerised information services . They have a fundamental direction , leading from one aspect ( beginning , prior , input , source , precondition , cause ) to another ( ending , posterior , output , sink , consequence , effect , result ) . And this area has nurtured several " schools " of art , from the Pennsylvania Impressionists to the Ashcan school , led by Pennsylvania Academy teacher Robert Henri .