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Topoisomerase-II-associated DNA strand breaks will also be quantified as doxorubicin is known to inhibit the strand passing reaction of topoisomerase-II . Presentations must be arranged around faculty teaching schedules , and planning is needed to find a suitable date and location for the event . Because monetary values can more readily be assigned to some impacts than others , care is needed to ensure that adequate consideration is given in any decision-making to all non-monetised items that may be thought significant , relative to the monetised elements . count is set to one . By February 1 , 2000 , the DEP is required to submit a report to the Governor , president of the Senate , and the Speaker of the House of Representative containing recommendations , including draft legislation , for any modifications to the process for allocating TMDLs .