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Our results show that not only does this complex resist considerable mechanical force through 0 strand crosslinking , suggesting that telethonin is an important component of the N-terminal titin anchor , but also that telethonin distributes these forces between its two joined titin Z2 domains to protect the proximal Z1 domains from bearing too much stress . This , together with its relatively small size ( similar to 5.5 angstrom along its longest axis ) , suggests that the pore-blocking choline binding site is the selectivity filter itself , and that current blockages simply reflect the longer-lived sojourns of choline at this site . Lead the responses to the subject of instructions , suggesting that the instructions may have been in the form of a diagram . If the person is really upset , or if you're worried that he or she might not follow through , suggest that the individual make an appointment now . A review of aviation security conditions in place prior to 9/11 , and the many federal actions taken since then to mitigate the known vulnerabilities , suggest that we have come a long way toward making air travel safer . Sara McLanahan of Princeton , agreeing largely with Cherlin , suggested that family difficulties and the serious problems many children confront might stem not so much from divorce but from couples not marrying in the first place . In the Senate , there is a more limited prohibition against considering unauthorized appropriations.Both House and Senate rules require that when the Committees on Appropriations report a bill , they list in their respective committee reports any programs funded in the bill that lack an authorization . Cathy Widom has done much of the best work and has a current study with Diana English in Washington State that , at least at the time I heard it presented in the summer of 1999 , suggests that this is still true and may be even more true than shown in the earlier research . The tilt mechanisms should apply to many oxide / metal systems , including thermal barrier coatings , solar cells , and interfaces in electronic devices , suggesting that the benefits of intentionally enhanced texture are achievable in many coated materials . However , data from a study conducted in 2004-05 in children aged 6 to 59 months by MedImmune , suggested that FluMist offered significantly greater protection than the flu shot . New findings in animals , however , suggest that even after a stem cell has begun to specialize , it may be more flexible than previously thought . One of the most thoroughgoing of the German socialists , Karl Kautsky , in his forecast of what might be expected to happen the day after the industrial revolution , suggests that when the State has taken a possession of the capitalistic industries it could sell a portion of them to the labourers who work them , another portion to co-operative associations , another to muncipalities , and still another to provincial subdivisions of the nation ( in America , the several States ) . In addition to McClure 's recommendations , there are requests from agency heads for recommendations on Idaho applicants . At Galmi Hospital [ which SIM built and operates and where the Harigs stayed ] , there is a walled compound , which boasts a western-like community with flowering bushes and trees . The endometrium has hemosiderin-laden macrophages after gestations , suggesting that there is some bleeding during parturition . They , therefore , suggested that these major differences found between Northern and Southern rock hyraxes are indicative of speciation in what is currently considered to be only one species , Procavia capensis . “ This group didn ’ t show any significant difference in plaque reduction as compared to controls , suggesting that once the plaque is deposited there ’ s very little that an antioxidant can do , ” says Pratic ò. The unnamed " Most Bigoted Man in the Valley , " who was eighty-four , suggested that blacks could have the vote in a thousand years ' time but rejoiced that he would not be there to see it . Nevertheless , the manner in which adolescent girls are forced into prostitution , early marriage or labour , and denied life chances , and their own inability to protect themselves from exploitation and abuse , suggests that participation rights lie at the heart of child survival , development and protection . When you open a bottle or can of soda , there ’ s a distinct sound . As for successful treatment of adolescent offenders , there is virtually no empirical research with respectable follow-up times .