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The only known risk factor gene for late-onset AD is a form ( allele ) of the apolipoproteinE ( apoE ) gene . If you are really interested in the physical ( as opposed to conceptual ) design issues that LAs deal with every day , it sounds to me like you would be happiest with a dual degree . Heat disorders generally have to do with a reduction or collapse of the body 's ability to shed heat by circulatory changes and sweating , or a chemical ( salt ) imbalance caused by too much sweating . Typically , these facilities are at a high risk because of ( 1 ) damage from flooding ; ( 2 ) erosion of stream banks , beaches , slopes , or bluffs ; ( 3 ) landslides ; or ( 4 ) wildfire . " Perhaps that should be seen as reassuring , but in the case where I might like to avoid what I perceived as totally unnecessary wasting of my time ( thrice in fact ) filling in information that I know the government has already entered somewhere in their databases it was very irritating .