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( D ) SEM image of collagen fibers interacting with ductal epithelial cells . We are unaware of any other genetic model of epithelial wound healing where cells appear to fail to sense wounds initially , but migrate normally once this block is overcome . Therefore , at regions of tumor cell invasion , collagen has been reorganized to a radial alignment from a random orientation , indicating a structural realignment of collagen fibers facilitates local invasion . " A comparison of the first version with the final result reveals the workings of Beckmann 's artistry . More notably , this naturalistic study presents novel and clinically important information about differences in treatment duration between specific atypicals and specific typicals ( of high - , medium - , and low-potency levels ; perphenazine , and haloperidol with prophylactic anticholinergic agents ) .