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For instance , extensive meta analysis of microarray data across different species has revealed that neighboring genes are likely to be co-expressed , even though they are not functionally related in any obvious manner [ 9,10 ] . Courbet has given himself a splendid appearance and for once in the history of self portraiture we know that it was justified . We are unaware of any other genetic model of epithelial wound healing where cells appear to fail to sense wounds initially , but migrate normally once this block is overcome . We showed that wound healing was delayed for 2 hours in mutant cells , but that once healing began , the cells moved as fast as wild-type . Phylogenetic conservation has been recently proposed as a very strong criterion to identify functionally relevant co-expression links among genes [ 11 ] . These corresponded to 62 , 67 and 97 ESTs pairs , respectively , covering on average 66 % of the proteins found in these complexes . At this point I think once more of the Espolio in terms of its subject and become more fully aware of the vividness of El Greco 's imagina tion . I , IA , and IL are the alignment identities produced by the best log-affine , affine , and logarithmic gap penalties , respectively . S , SA , and SL are the maximum alignment identity produced for each sequence pair by log-affine , affine , and logarithmic gap costs respectively . Nevertheless , even when the co-expression of two genes is reproducibly observed under a certain number of experimental conditions , this does not imply necessarily that they are functionally related . The percentages of PT 4 and PT 6 among human S. Enteritidis infections in Austria and Denmark , respectively , have been reported to be decreasing in the last years [ 6 ] . The average number of candidates produced by CLOE for each analyzed protein was approximately 17 , which represents a strong reduction if compared to the single organism approach ( 746 and 375 for the human and mouse datasets , respectively ) . He must have placed naked models in front of him and painted them so faithfully that later generations were somewhat shocked by so much honesty . Our observation was that once a patient has developed severe psychotic symptoms he is restrained ( e.g . This suggestion , for now , is based on the similar physical properties of PEP-CTERM and LPXTG transmembrane domains , the recurring association of EpsH genes with large exopolysaccharide biosynthesis loci , and the suggestion that the absolutely conserved residues Cys , Arg , and His found in the EpsH family are not merely fortuitously like the known catalytic triad His , Cys , and Arg ( a different order ) in the sortase family .