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Effects of using : can stay in the body several days to several weeks later . Mood disturbances , kidney and other tissue damage , etc. Effects of using : dilated pupils , increased temperature , increased heart rate , increased blood pressure , heart attacks , seizures , headaches , gastrointestinal complications , nausea , loss of sense of smell , nosebleeds , problems swallowing , hoarseness , chronically runny nose , etc. Sometimes , it can be hard to tell the difference . problems with memory and learning ; distorted perception ( sights , sounds , time , touch ) ; trouble with thinking and problem solving ; loss of motor coordination ; increased heart rate ; cancers ; weakened immune system , etc. Effects of using : rapid heart rate , irregular heartbeat , increased blood pressure , irreversible damage to small blood vessels in the brain , inflammation of the heart lining , skin abscesses , decreased appetite , aggression , paranoia , depression and irritability .