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Issue clinical guidelines to grantees ( which can be used to compliment national practice guidelines ) that identify critical migrant health risk and patient management and education issues , including pesticide exposure and other occupational risks , common communicable diseases , and socio-economic and cultural factors which impact patient care and education and behavioral health . Corticotropin releasing factor ( CRF ) is a neuropeptide associated with the integration of the physiological and behavioral responses to stress . One study estimated that of the approximately 4 million women who give birth each year in the United States , 2.6 million use some amount of alcohol during their pregnancy ,2 and another study has estimated that up to 22,000 children per year ( approximately one-half of 1 percent of all births ) experience mild , moderate or severe adverse effects as a result of their mothers ' alcohol ingestion.3 Among the problems children may suffer are fetal alcohol syndrome ( FAS ) , which produces slowed growth , damage to the nervous system , facial abnormalities and mental retardation ; and fetal alcohol effects ( FAE ) , which produces a milder group of mental and behavioral problems , including short attention spans , memory problems and disorganization . Several lines of evidence support the hypothesis that compulsive drug seeking and drug taking behavior are attributable , in part , to dysfunctions in the neural systems mediating incentive motivation and behavioral regulation ( e.g ., the striatum , amygdala and ventral frontal cortex ) . Neuroscience , the study of the organization and function of the nervous system from a molecular , cellular , systems , and behavioral perspective , forms the basis for the program .