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By introducing or encouraging such enemies , the population of pest organisms should decline . The Institute is responsible for the completion of the sequence of approximately one-third of the human genome and one-fifth of the mouse , The Institute is also a major contributor to the mapping and sequencing of the zebrafish genome and genomes of more than 90 disease-causing organisms , including TB and malaria . The brucellosis organism is shed by the millions in the afterbirth and fluids associated with calving and aborting . " A treatment is here defined as those variables manipulated by the experimenter in the expectation that the biology of the test organism will be affected , leading to changes in transcription of certain mRNAs . He added various potential foods to cultures of the test organism and quickly discovered that the organism did not utilize his first choices , carbohydrates and protein components . Coyotes have been shown to shed the brucellosis organism in their feces for several weeks following ingestion of infected material . For purposes of validating the effectiveness of any of the above mentioned treatments , the Contractor shall review indicator organisms that could be used to determine treatment effectiveness . A lack of quantitative ( variable ) baseline data for E. coli O157 : H7 , or appropriate indicator organisms such as E. coli biotype 1 , coliforms , and / or Salmonella , on primal and subprimal cuts of beef immediately prior to blade tenderization was identified . Therefore , a risk analysis in the context of TMDLs for indicator organisms such as fecal coliforms is important in protecting human health in watersheds with complex land use and multiple bacterial pollution sources . The brucellosis organism localizes in the testicles of the bull and produces an orchitis ( inflammation of the testicles ) , whereas in the female the organism localizes in the udder , uterus , and lymph nodes adjacent to the uterus .