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Our results indicate that some probe sets should not be considered as unique measures of transcription , because the individual probes map to more than one transcript dependent upon the biological condition . Virtually all clinical developmental studies in infants have examined visual and cognitive outcomes [ 19 ] , and are limited to sampling of blood for assessment of tissue responses to supplementation , rather than the target CNS tissues . We therefore asked whether we could detect H-Ras mutations in mammary tumors induced by an MMTV-Wnt1 transgene in a p53-null background ; a failure to find such mutations would imply either that p53 is somehow required for such mutations to occur or , more likely , that an inherited deficiency of p53 conferred a growth advantage to Wnt1-expressing mammary cells that would outweigh any selective advantage provided by a secondary somatic mutation in H-Ras . Using an episode-of-care approach provides comprehensive information about the multiple courses of treatment per participant in the longitudinal treatment of the illness [ 20 ] . It is not clear whether the keratopathy is a direct result of reduced PAX6 gene dosage in the cornea itself , or due to recurrent corneal trauma secondary to defects such as dry eye caused by loss of PAX6 in other tissues . Treatment group comparisons on time to all-cause medication discontinuation were first made between the atypicals as a group versus typicals as a group , then between the atypicals ( singly and combined ) and typicals of high potency , medium potency , and low potency levels . Case controls were asked about consumption in the week prior to the interview and for consumption at the age of symptom onset reported by his / her examined case-pair ( Table 2 ) . Inspection of protein markers provides important information about the current state of the cells and data for subsequent manipulations . The figures include all passengers carried on flights from any CAA airport to their first foreign destination , without indicating whether this destination is for transfer or the final destination . Conventional Giemsa-stained karyotypes or spectral karyotypes have a resolution of about 1 – 5 Mb . Current findings are , however , inconsistent with a meta-analysis by Wahlbeck and colleagues [ 35 ] , who reported lack of significant differences in dropout rates between typicals and atypicals other than clozapine . A complete veterinary examination was performed upon arrival in Ithaca . Enrollment was not contingent upon being treated with a specific antipsychotic or with any medication . This covariate replaced another covariate used in the main analyses ( time elapsed between medication initiation and beginning of US-SCAP ) . We found significant correlations between variables of khat consumption and clinical scales ( 0.35 to 0.50 ; p < 0.05 ) , and between the age of onset of khat chewing and symptom onset ( 0.70 ; p < 0.001 ) . Despite the ongoing scientific debate about amphetamine-induced psychosis it remains unclear whether the use of amphetamine-like substances including khat may actually cause a psychotic disorder in an otherwise healthy individual , or trigger the onset of schizophrenia in an individual with high vulnerability to the disease [ 24,25 ] . Between the ventral most inner ( if ) and outer folds ( of ) lies the periostracal groove ( § ) . It is presently unclear , however , whether traumatic experiences act indirectly through higher drug consumption in traumatized men or whether they exert a direct effect on the brain , increasing the risk of developing psychosis . Her-2 / Neu acts in part through the Ras signaling pathway [ 22-24 ] , a feature that may account for the remarkable similarity between the phenotypes of mammary tumors found in MMTV-Neu and MMTV-v-H-Ras transgenic mice [ 25 ] . Experimental work will be required to determine when PEP-CTERM proteins are expressed , where they localize , whether they are processed at the C-terminus , and whether EpsH proteins are required for sorting and / or processing .