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" If the extented HTTP stream is the full " address " to include ( by way of continuing analogy ) to the county , street and house number , and postcode that is the address on the envelope which leads to the " content " ( or where the content is going ) , but does not constitute the content its self , i.e ., the actual file to be recovered from the site . It also throws bad light on the capacity of the Clinton administration to get things done in Congress , even to the extent that an issue like sanctions against Pakistan which is said to have bipartisan support , cannot be pushed conclusively ahead . Third-degree burn : Areas that are white , leathery , and insensate denote full-thickness injury.Determining extent of involvement requires an estimate of the affected body surface area . To what extent is such knowledge learned from the culture , and to what extent might it be " hard-wired " into the species ? Issue : Coastal watersheds in the Northeast are generally degraded to varying extents . Estimated boundaries for large Classic period sites commonly incorporate the overlapping areal extents of all earlier components . In these cases the examiner must determine the extent of the bartering and ensure the value of goods provided is included in gross receipts . For high-throughput in silico secretome analysis , we also develop bioinformatics tools ( see : http://SignalFind.org ) that predict different classes of Sec and Tat substrates and thus allow us to ask intriguing questions such as : i ) what are the selective pressures for secreting certain substrates in a folded conformation via the Tat pathway , rather than via the Sec pathway , which secretes proteins in an unfolded conformation and ii ) why is the Tat pathway used to such varying extents among prokaryotes . When these additional observations were used to update the orbit of 2004 MN4 , the uncertainties associated with this object 's future positions in space were reduced to such an extent that none of the object 's possible trajectories can impact the Earth ( or Moon ) in 2029 . Of the remaining wetlands , many are degraded to varying extents by weed invasions , modifications to hydrological regimes , and barriers to fish migration . " Naturally , Marx , Engels , Lenin , Trotsky , and even the left of the party , believed this to varying extents .