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Viperid venoms , on the other hand , contain an abundance of protein-degrading enzymes called proteases , which produce the symptoms like those encountered by the unlucky rattlesnake handler : strong local swelling and necrosis , and blood loss from cardiovascular damage complicated by coagulopathy , or disruption of the blood clotting system . When Federal credit assistance is necessary to meet a Federal objective , loan guarantees should be favored over direct loans , unless attaining the Federal objective requires a subsidy , as defined by the Federal Credit Reform Act of 1990 , deeper than can be provided by a loan guarantee . It has been gratifying to guide young wildlife managers , park staff , and graduate students there , and to encourage and support projects that help us understand and resolve the intersecting issues of parks , wildlife conservation , and human communities . It works by allowing the user to select a locality record , quickly locate the referenced place on a base map , and to draw a shape that represents the user 's interpretation of the locality .