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The posterior zone of the outer fold ( pzof ) , anterior zone of the outer fold ( azof ) , periostracal groove ( pg ) , inner fold ( if ) , and anterior edge of the outer fold ( aeof ) are indicated . ( W and w ) HasSom expressed discontinuously within the anterior zone of the outer fold the mantle . The principle of using the phylogenetic profile of a DNA cis-regulatory site to identify a DNA-binding protein was demonstrated in the case of the NrdR-box associated with ribonucleotide reductase genes ; leading to the identification of the NrdR-box binding protein [ 45 ] . This pool shows great concordance of expression with individual normal hESC lines , as the correlation coefficients ( r2 ) with normal lines average 0.87 , or 0.93 for genes expressed at high confidence levels . Thus , for example , he upbraids us for not mentioning the experiments and observations that have supported relativity theory during the second half of the twentieth century . This modest symbol of Rembrandt 's craft becomes itself a light source of almost spiritual dimensions , casting a halo in the atmosphere around Rembrandt 's head , and against the dark background .