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Susceptibility to arthropod bites depends on many external factors ( eg , occupation , conditions of employment , cohabitation with a variety of domestic animals , housing , climate , clothing ) . Excerpt from Chronic Granulomatous DiseaseSynonyms , Key Words , and Related Terms : CGD , fatal granulomatosis of childhood , immunodeficiency disorders , X-linked recessive disorder , gp91phox , p22phox , p67phox , Xp21.1 , Rac2 , impaired phagocytic function , defective cytochrome b function , oxidase absence , oxidase malfunctionPlease click here to view the full topic text : Chronic Granulomatous DiseaseBackground : Chronic granulomatous disease ( CGD ) is a primary immunodeficiency that affects phagocytes of the innate immune system and leads to recurrent or persistent intracellular bacterial and fungal infections and to granuloma formation . - No department , agency , officer , or employee of the United States may - '' ( 1 ) require that any record or portion thereof generated by the system established under this section be recorded at or transferred to a facility owned , managed , or controlled by the United States or any State or political subdivision thereof ; or '' ( 2 ) use the system established under this section to establish any system for the registration of firearms , firearm owners , or firearm transactions or dispositions , except with respect to persons , prohibited by section 922 ( g ) or ( n ) of title 18 , United States Code , or State law , from receiving a firearm . Alternatively , specific events , such as deep venous thrombosis , surgery ( eg , vein stripping , harvesting of saphenous veins for coronary bypass ) , or traumatic injury , can severely damage the function of the lower-extremity venous system ( see Image 2 ) .