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In captured images , the second and sixth cell rows from the wound edge were drawn . Unlike treatment with other antipsychotics , treatment with clozapine requires periodic blood monitoring to assess the risk of developing agranulocytosis . Each of the early passage lines studied here was shown to be genetically distinct from the others . The gene-expression profile of pluripotent hESCs has not been completely defined , but much work has been carried out toward defining common sets in undifferentiated and differentiating hESCs [ 12-14 ] . Marginal cells of stria vascularis , which form the barrier toward endolymph , transport K + from the intrastrial space into endolymph and keep the K + concentration low adjacent to the KCNJ10 K + channel [ 26 ] . The fifth and last sensitivity analysis was an intent-to-treat ( ITT ) analysis , which unlike previous analyses also included initiators on the index drug who did not have data for at least 1 year following initiation . Our data suggest , however , that this is not the case , and that the link between genetics of disease and pharmacological correction ( in this case via EGF ) may not be so esoteric . Our findings of differential treatment duration in usual care between typicals and atypicals are also consistent with previous reports of a lower rate of treatment failure and longer time to drug discontinuation [ 11,30 -33 ] among schizophrenia patients treated with atypicals compared with typicals . Work is proceeding toward conditions that support the propagation of all lines [ 11 ] , sets of markers that truly define the undifferentiated and unadapted state of the cells [ 7,12 -14 ] , and markers predictive of the differentiation capacity of the cells [ 15 ] . However , unlike aspirin , some , but not all patients , treated chronically with naproxen maintain suppression of thromboxane throughout the whole dosing interval at a level compatible with effective platelet inhibition [ 10,11 ] . a Calculated via a t-test for age , size , and estrogen-receptor protein , via Fisher 's exact test otherwise . Figure 4 demonstrates that the likelihood of staying on an atypical antipsychotic compared to typical antipsychotics ( combined ) differed among the atypicals , such that only clozapine , olanzapine , and risperidone had consistently longer time to medication discontinuation compared to treatment with typical agents . We therefore link a transcription factor mutation , via defects in calcium signaling , to a cellular abnormality that underlies human disease . However , the intensity and speed of propagation of the calcium wave , mediated by release from intracellular stores , was reduced in Pax6 + / - cells . The change in phage type distribution observed among Swedish travellers returning from some countries in Southern Europe in 2001 was not observed among inhabitants in the countries visited . Local interviewers were recruited among NGO and hospital staff who already had experience in working with mentally disabled persons . This is the same approach used with Affymetrix SNP arrays to determine copy number [ 21 ] ; however , reference BeadArray data from known diploid loci is required to translate intensities into copy number . These findings were driven primarily by clozapine , olanzapine , and risperidone , as quetiapine did not consistently differ from haloperidol with prophylactic anticholinergics , and treatment with ziprasidone did not significantly differ from haloperidol with prophylactic anticholinergics on any of the 3 statistical approaches . Using these figures as denominators , we calculated annual incidence rates for countries reported as place of infection for the three most popular countries for charter tourism among Swedes – Spain , Greece and Turkey . We hypothesized that if " sponsor-related physician bias " were present , physicians would have quickly switched patients from their current antipsychotic to olanzapine rather than to risperidone ( olanzapine , risperidone , and clozapine were available for all patients at the time of enrollment , unlike quetiapine and ziprasidone that were not yet available to early study enrollees ) .