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" Compared to abusers of other illegal drugs , " he says , " methamphetamine addicts have an unusually high failure rate . Bean 's role in Mexico 's revolution against Spain and his service as an agent of the Mexican government , especially as an Indian agent in eastern Texas , provide an unusually vivid picture of Mexican Texas , as well as new information about the Indians in this region . Affected individuals may also lose their teeth earlier than normal , have an unusually deep voice , and / or experience hearing loss . Many infants and children with the disorder have an unusually small , short head ( microbrachycephaly ) ; an abnormally long vertical groove between the upper lip and nose ( philtrum ) ; a depressed nasal bridge ; upturned nostrils ( anteverted nares ) ; and a protruding upper jaw ( maxillary prognathism ) . Many affected individuals also have an unusually large tongue ( macroglossia ) that may partially block the respiratory tract , potentially causing breathing and feeding problems . Affected individuals typically have an unusually flat , underdeveloped midface ( midfacial hypoplasia ) , with an abnormally short nose and flat nasal bridge ; underdeveloped upper jaw ; relatively protruding lower jaw ( mandible ) ; and / or a " reverse overbite " ( class III malocclusion ) . Previous studies have focused chiefly on the situation of Finnish-speaking immigrants in Sweden and of returning immigrants from Sweden , despite the fact that Swedish-speaking Finns represent an unusually high proportion of all Finnish immigrants in Sweden .