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Nuts appear to reduce risk of heart disease . Pregnancy , breast-feeding and the use of oral contraceptive pills appear to reduce risk . On the positive side , they do appear to reduce risk of heart disease . Given to women with gestational diabetes , TZDs appear to cut risk of developing type 2 diabetes . Not only do some diabetes drugs appear to reduce risk of heart disease but some heart drugs may stave off diabetes . Even water with a moderate concentration of fluoride - - 0.3 to 0.69 milligrams / Liter - - appeared to boost risk in boys more than threefold . But Weirich 's proposal appears to make risk a function of the whole gamble and of one 's current utility level , in such a way that no addition to the prizes can make a game desirable to a risk-averse agent . The use of enteric-coated or buffered preparations did not appear to reduce risk . Supplementation with vitamin E , though , does not appear to improve risk of cancer .