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Your muscles ( and skeleton ) continuously change in shape and size by very small amounts to keep pace with your lifestyle , but to make muscles grow unusually big , you need to take unusual exercise - like working out on special machines for long periods in a gym . They have large rows of very rough grinding teeth , with very pwerful jaw muscles , so that a large proportion of the plant cells are burst , releasing the nutrients within , before they are swallowed . Being big and tough might be fine when food is plentiful , but when there is a bad summer , or a volcanic eruption , the animals with the biggest appetites will get hungry first . So , natural selection could operate to increase the frequency of O alleles in a number of ways ; the O phenotype may be advantageous in some cases , balancing selection could operate to maintain elevated levels of O alleles , and intrauterine selection could favor O phenotype men . Large body size has another surprising evolutionary consequence - big animals are more vulnerable to extinction . They do n't seem to serve any purpose at present , but if they are under genetic control , and if they became advantageous in a particular environment , then the proportion of the population carrying them would be expected to increase . Think of a big eBay arrangement where the lowest price wins . If you still want to go ahead , it is best to remove the skin and guts , and any large pieces of flesh which are easy to remove , such as on the upper legs . In order to determine if reverse osmosis / total mineral removal is the right way to go , consider the application for which you will use the water . I 'm afraid I do not know the titles of any recent publications , but you should be able to find some by asking in a large bookstore , or searching Amazon . For example , the University 's purchasing unit has realized annual savings of over $ 1.0 million from 14 reverse auctions over the past two years . Possible areas we are exploring for assessment include our first-year seminars ; the effectiveness of out-of-class experiences , such as study abroad , service learning and internships ; evaluation of student learning in General Education courses , and the impact of student support services . In reverse auctions , the University posts the volumes of products that we want to purchase , and vendors electronically bid to provide the products at the lowest prices . There is one big problem with permanently altering the position of the jaw - your teeth will cease to be correctly aligned . The animals discovered are of course nearly always small , but there are tantalising pieces of evidence that very large squid may exist , and if they do , there are probably more than one species .