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Size correlates with the number of times the related gene name occurs in association with the gene in question – in this case Brca1 . Apparently , the identity of the artist-patriot seemed most agreeable to the youthful Rembrandt . While this feature would pose serious problems , if one should attempt to average the data of all the probes belonging to the same gene , it may offer extremely valuable information when every EST is considered independently , since each clone explores the expression properties of a particular group of exons , in a particular combination of experimental situations . The angularities of trouble are cut short , their halt made less abrupt by a fringe of trees , and there appears in the clear winter sky , capped by a golden dome , a circlet of angels so light , so free in their ecstatic movement from the discords of human conflict , that they remain in the mind 's eye as the purest expression of heavenly bliss . We demonstrate the capabilities of the approach by testing its predictive power on three proteomically-defined mammalian protein complexes , in comparison with single and multiple species meta-analysis approaches .