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Given this evidence of progression , it is clear that a miner who may be asymptomatic and without significant impairment at retirement can develop a significant pulmonary impairment after a latent period . When there is a particular health problem that has an expected progression , the changes tend to be more subtle and can be planned and managed as the family adapts to the definition of the disease .. And some , through the default of their memories , who cannot retain the several combinations of numbers , with their names , annexed in their distinct orders , and the dependence of so long a train of numeral progressions , and their relation one to another , are not able all their lifetime to reckon , or regularly go over any moderate series of numbers . First , ancient arts and wisdom are lost due to modern invention and progressions , and second , that the ancient world , because of this , was a much more pleasant place to live than many believe ( at least for those with some wealth ) . With continuing disease progression , affected children typically develop restricted movements of certain muscles due to progressively increased muscle rigidity , severe mental retardation , hearing and visual impairment , and a lack of response to stimuli in the environment . The vocabulary of diatonic scales and modes , chords and their relationships , phrase structure and cadences , harmonic progressions , non-harmonic tones and the technique of harmonization . AB - Anaplastic Wilms ' tumors are commonly believed to be rare forms of progression , driven by p53 mutations , of the more common classical Wilms ' tumor or nephroblastoma Contrary to classical Wilms ' tumors , anaplastic tumors traditionally tend to metastasize , to be drug-resistant and to have a poor prognosis . If you would like to be part of a more developing arm with great career progression , bonus potential and commercial support then this may be ...