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Then you pick up the message , try the procedure , and are left with no interactive support when you hit a snag or discover that you really need to do something entirely different . Instead of asking nicely , we get what we want by sheer force . So there I am , running around with my baseball mitt , trying to catch long , towering pop-ups , laser-beam line drives and sharply hit grounders that scoot along the carpeted floor like angry ferrets . The only reason that you should consider really concentrating your portfolio ( and here I mean fewer than eight selections ) is if you commit to knowing a ton about these businesses and have the utmost confidence in the earnings estimates you build for them . Individual brain cells segregate into specialized areas by expressing a wide spectrum of specific housekeeping proteins , enzymes , transporters , and receptors .