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Radioactive images were analyzed and quantitated by a phosphoimager . About a third were diagnosed with schizoaffective disorder and 28.8 % with comorbid substance use disorder . It is not clear whether the keratopathy is a direct result of reduced PAX6 gene dosage in the cornea itself , or due to recurrent corneal trauma secondary to defects such as dry eye caused by loss of PAX6 in other tissues . In vivo , the chronic delay in sealing small holes caused by minor abrasion or other cell loss may be sufficient to allow the corneal stroma to become compromised , leading to opacity . Forty-nine of the 52 examined cases and one control were diagnosed with psychiatric or neurological disorders ( on this basis we estimated a sensitivity of 0.98 and a specificity of 0.94 for the screening procedure ) . Consensus on the importance of continuous treatment with antipsychotics has been accompanied , however , by an ongoing debate over whether the newer " atypical " antipsychotics are superior to the older " typical " antipsychotics in the treatment of schizophrenia [ 8-13 ] . The antiviral effect ( IC50 ) was quantitated by comparing the values obtained from the episomal bands with those from linear bands as described [ 32 ] . Despite the austerity of his early Cubism , Braque 's interpretation of Cezanne was more painterly than that of Picasso , and he was undoubtedly fascinated by the surface quality and the actual technique of Cezanne ; there is in the handling of the sky in the Harbor in Normandy , and indeed throughout the whole picture , a much greater emphasis on the richness of the pigment itself than there is in contemporary works by Picasso .