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PrecautionsCaution with renal or liver disease ; avoid during pregnancy ; occasionally , patient with SLE has hypersensitivity reaction , most often characterized as hepatotoxicity , but reaction can include other symptoms and must be kept in mind ; routinely monitor for gastritis , renal toxicity , hepatic toxicity , and bone marrow suppression , hepatitis , interstitial nephritis , CNS changesDrug NameDiclofenac ( Voltaren-XR ) - - Inhibits prostaglandin synthesis by decreasing activity of enzyme cyclooxygenase , which decreases formation of prostaglandin precursors . By that definition , the league 's leading scorer - - before and after the brawl - - deserves to make the cut . Microsoft 's Office suite has more than 90 per cent of the desktop productivity suite market , and Outlook - - its e-mail , calendar and personal organizer component - - enjoys a comparable domination of the e-mail world . Stephenson believes that most of the knowledge crucial to an organization - - whether it 's Bell Labs or the Marines - - comes from common hands-on experience . The focus on thinking " beyond gigahertz " - - and arguably , the interest in bringing 64-bit processing to the Pentium - - comes following Intel 's much-publicized inability to boost the Pentium 4 to 4GHz . When he was through , he raised his head and spoke to his expectantly waiting officers : " Mikhran marzban requests - - begs - - our aid . These drugs are not needed in NLE but may be used in children with skin or joint disease of SLE.Drug NameHydroxychloroquine ( Plaquenil ) - - Inhibits chemotaxis of eosinophils and locomotion of neutrophils and impairs complement-dependent antigen-antibody reactions . PrecautionsCategory D in third trimester of pregnancy ; caution in congestive heart failure , hypertension , and decreased renal and hepatic function ; caution in coagulation abnormalities or during anticoagulant therapyDrug NameKetorolac ( Toradol ) - - Inhibits prostaglandin synthesis by decreasing activity of enzyme cyclooxygenase , which results in decreased formation of prostaglandin precursors .