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The project will include the development of a number of circuit ideas for linearizing the transmitter that capitalize upon the unique capabilities of monolithically integrated driver and transmitter . " On Thursday , Seeger was trying to figure out what went wrong in his case , and he criticized Merck for attacking the credibility of his client by suggesting he was not taking the drug at the time of his heart attack . Time-of-flight instruments when coupled with matrix assisted laser desorption ionization ( MALDI ) result in extremely high sensitivity ( sub pmol ) which is a desirable asset for determining the primary structure of peptides . The Great Lakes water resources have played a pivotal role in the development of the binational region but their protection and wise use are equally important for enhancing the region 's quality of life .