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Statistical parametric maps of the single-group analyses for ε 3/3 homozygotes ( panel A ) and ε 3/4 heterozygotes ( panel B ) , and for regions where the ε 3/3 homozygotes activated to a greater extent than the ε 3/4 heterozygotes ( panel C ) . Thus , an effort could be made to introduce standardized serum-free conditions for the growth of NTERA-2 and validate the reproducibility of its gene expression across laboratories in order to create an unlimited source of reference material for hESC . In this report , we have used several features of recent studies of breast carcinogenesis in genetically manipulated mice to explore the contributions made to a multi-step oncogenic process by a variety of inherited and somatic mutations . ( D ) Median Z-scores for each motif in each of the subnet ensembles and the Z-score of the motif in the full network .