[tag=□] □
[tag=JJ] □
It is not clear whether the keratopathy is a direct result of reduced PAX6 gene dosage in the cornea itself , or due to recurrent corneal trauma secondary to defects such as dry eye caused by loss of PAX6 in other tissues . To further assess the robustness of the findings , sensitivity analyses were performed , including the use of ( a ) only 1 medication episode for each patient , the one with which the patient was treated first , and ( b ) all medication episodes , including those simultaneously initiated on more than 1 antipsychotic . Using each profile-positive genome in turn , we scored every protein in that genome for its correlation between a phylogenetic profile and the list of related sequences in other genomes as measured by BLAST comparison . The treatment groups differed in age , gender , ethnicity , comorbid diagnosis of substance use disorder , psychiatric hospitalization in the 60 days prior to medication initiation , time elapsed between medication initiation and beginning of the US-SCAP study , schizoaffective disorder diagnosis , and duration on any antipsychotic in the 60 days prior to initiation on the index antipsychotic . The covariates included age , gender , ethnicity , comorbid diagnosis of substance use disorder , psychiatric hospitalization in the 60 days prior to medication initiation , time elapsed between medication initiation and beginning of the US-SCAP study ( 01/07/1997 ) , enrollment site ( 1 – 6 ) , schizoaffective disorder diagnosis ( yes / no ) , and duration on any antipsychotic in the 60 days prior to initiation on the index antipsychotic . Others also reported [ 12 ] that olanzapine is not more efficacious than haloperidol when haloperidol is provided with prophylactic anticholinergic treatment to help ameliorate EPS . As a control , we performed the same analysis on an equal number of randomly chosen ( and hence non-orthologous ) human-mouse EST pairs . The list of matching sequences from other genomes was sorted from the most significant match to the least .