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And , Dr. Smaldone , is that your understanding as well , that these patients who have been helped , have been helped under the compassionate-use doctrine , and that in fact for these colorectal cancer patients who have no other help , that your company and ImClone can provide the drug to them without pre-approval by the FDA . The key legal issue in the transition to competition for the city DOT franchises will be determining the applicability of Section 13 ( c ) of the Federal Transit Act. [ 40 ] Section 13 ( c ) requires that in order for any public agency to receive federal transit grants , the labor rights , privileges and benefits under existing contracts have to be preserved and continued . What I do want to do though is underscore that in order for that to happen that we are going to need to shrink the environmental footprint of this energy source significantly , and that is due to a lot of scientific evidence , as well as technology improvements in the last decade . It seems that in order for all parties to get maximal protection from errors , there should be multiple independent levels of redundancy and record keeping . As in earlier passages , so here in speaking of profit and loss , the point of view taken is neither that of material advantage , whether of the individuals concerned or of the community at large , nor that of expediency for the common good in respect of prosperity or of morals ; nor is the appraisal here ventured upon to be taken as an expression of praise or dispraise at large , touching this incursion of business principles into the affairs of learning.By and large , the intrusion of businesslike ideals , aims , and methods into this field , with all the consequences that follow , may be commendable or the reverse .