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" Although we have derived quite a few results , we leave many open questions , " Licht concluded in his STS research paper . Beta blockers — which are commonly used to treat high blood pressure and coronary artery disease — can reduce the frequency and severity of migraines . Among the most important are Taylor 's notions of question negotiation ( encompassing self-help and a variety of other modes of satisfying information needs ) . It is first populated with the primary resources or references via metadata to them , which are shown as red nodes . Each example that follows has an accompanying figure , where the circles represent nodes in the information network , which are implemented as Fedora digital objects . The models indicate that what happens typically depends on traffic volume - - a combination of vehicle density and average speed . The file formats , metadata requirements and software applications used to manage and view e-prints can all be used to manage and disseminate other forms of electronic content , and this means that the e-prints community will not have to solve the technical problems which are unique to e-prints . Early digital library work formulated the notion of digital objects , which are packages of information with multiple disseminations available through service requests [ 22 , 26 ] .