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A major problem with the approach used by these investigators is that over half the study population had been trying to conceive for greater than one year prior to the beginning of the study . The nasal and oral cavities are innervated by the trigeminal nerve , the nasopharynx by the glossopharyngeal , and the oro - and hypopharynx by the vagus ; these nerves project to various areas of the brainstem . Although small increased risks have been reported in some studies , the results are difficult to interpret given that they were based on small numbers , with wide confidence limits , and the dose-response trends were largely not smooth . He thought that the sooner the Adelante trains are gone , the better , because there is not enough room for bicycles on them . The average rate of penetration for all coring bits was 1.6 m / hr .