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Some have reported comparable efficacy [ 12 ] and questioned the claims of superior efficacy of atypicals relative to typicals [ 8,12,13 ] because clinical trials have often established efficacy of the atypicals in comparison to haloperidol , a high-potency typical antipsychotic known to have pronounced treatment-emergent extrapyramidal symptoms ( EPS ) that may contribute to poorer treatment outcomes . The de-identified lists were refreshed every 6 months to replace the patients that had been recruited , until each site reached the enrollment target ( 400 patients ) . The RNA polymerase protein sequence is shaded in red and the intein sequence in blue . Psychotic symptoms were assessed using the items of the WHO Composite International Diagnostic Interview and quantified with the Positive and Negative Symptoms Scale . They achieve their purpose by pure outline , which floats and dances with the same disregard of substance as thirteenth century illustrations to The Tale of Genji . Findings from that post hoc analysis were almost identical to the present study . In the first sensitivity analysis , only the first episode for each patient was used ( N = 1028 ) . Each line has a unique histocompatibility profile , while the two sublines SA02.5 and BG01V are identical to their parental lines . Regulatory networks often employ the model that attributes changes in gene expression levels , as observed across different cellular conditions , to changes in the activity of transcription factors ( TFs ) . Khat consumption ( number of bundles / week ) was assessed for the week prior to the interview .