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There has been intense interest in DHA and its influence over function in the developing CNS . On average , cases with psychotic symptoms had started to use khat earlier in life than matched controls and had been using khat 8.6 years before positive symptoms emerged . These results indicated a protective effect of THC against destruction of host cells by the virus and suggested that THC may inhibit MHV 68 replication . Mammary tumors reported in the MMTV-Neu monotransgenic line used here have usually acquired mutations in the Neu coding domain of the transgene , enhancing the enzymatic activity of its product ; about 70 % of these tumors exhibit point mutations , small deletions , or insertions in the extracellular portion of the receptor in or near the cysteine-rich domain encoded by nucleotides 1492 – 2117 of rat Neu cDNA [ 17 ] . Furthermore , it seems that it is not the consumption of khat per se but rather specific patterns of it that are related to psychosis , especially early onset in life and the excessive intake ( > two bundles per day ) . Local interviewers found that rates of severe disability due to mental disorders were 8.4 % among males ( above the age of 12 ) and differed according to war experiences ( no war experience : 3.2 % ; civilian war survivors : 8.0 % ; ex-combatants : 15.9 % ) .