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She edits the Bee column in several papers ; at Bee conventions her opinion is eagerly sought on all questions which come up ; and such is her superior judgment upon Bee culture that it has received recognition from the Government itself . It is the ballot ; it is a practical interest in the laws which govern them ; it is the thought awakened by the responsibility of self-government . It is more than an object-emblem or an accumulation of aspects ; it is , rather , a personal metaphor , like the guitar . Both calcium and ERK responses are sensitive to EGF , which is present in tears at 1 – 10 ng / ml [ 66 ] , and we show that calcium response to EGF is diminished in heterozygotes ( possibly due to mislocalisation of EGFR in the mutant epithelium [ 6 ] ) . My hope in this book is to bring alive in the reader 's imagination the person and artist Winslow Homer , the man who gave us who gives us pictures that on first look are transparent ; at closer study become reticent ; and on reflection evoke what is ultimately inexplicable , the course of human life and the universe in which it unfolds . You might not live long enough to do that!Seems to me that one of the problems most of us would face is that we rely on modern technology without really understanding it ; at least to the extent that we could n't build anything to impress them . We achieve these ways of being and acting in a complex network of ever widening social experience to which we contribute : who we are in our family ; who we are as individuals in a larger social environment ; what our work will be and , once we have chosen it , how we fare in it ; whether we will marry , and what that choice will mean in relation to the paths of the older and younger generations in our family ; who we have become in our middle years and its relationship to our earlier dreams ; and as we near and enter old age , what our lives have meant , to others and to ourselves . Calcium signaling occurs in the first 2 minutes , whereas ERK1 / 2 signaling is expected to peak about 3 – 10 minutes after wounding [ 34 ] . The subject fascinated him , but the old stiff iconography was doubly unacceptable ; it lacked that sense of movement which for thirty years had been the chief aim of Florentine art ; and it failed to express his feeling of continuous involvement between mother and daughter . " " Apparently , there was a period when every college dormitory in the country had on its walls a poster of Hopper 's Nighthawks ; it had become an icon . For example , the expression profiles of tumors reflect the transgenic oncogene [ 5 ] ; moreover , those tumors induced by genes that activate the Ras signaling pathway ( for example , polyoma middle T antigen , ErbB2 / Neu , and H-Ras ) are more similar to each other than to tumors induced by components of the Wnt signaling pathway ( Wnt1 , β - catenin , and c-Myc ) with respect both to gene expression patterns ( [ 5 ] , S. Huang et al ., in preparation ) and to cellular composition and histology [ 6-9 ] .