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While it depends on the choice of reference genome , it can be run separately for each genome in the profile . The enhancer-dependent sigma factor binding site linked to proteobacterial PEP-CTERM genes is phylogenetically correlated to a transmembrane histidine kinase , which suggests an interaction with , and perhaps a contribution to , the external milieu of the cell . The globus pallidus has the highest DHA concentration at 15.8 0.5 % ( w / w ) , while the optic nerve is lowest at 4.5 0.4 % . Whereas the information given by examined cases could be validated by the information of family members , we were well aware of the danger that the matched controls might have under-reported their khat intake . When direct comparisons between typicals and atypicals were performed in another meta-analysis [ 36 ] , the findings supported the superiority of atypicals over typicals on " treatment failure " that captured dropout rates and symptomatic relapse . Although the proposed method is tested on a SRBCT data set , it is quite general and can be applied to other cancer data sets . There is an ongoing debate over whether atypical antipsychotics are more effective than typical antipsychotics in the treatment of schizophrenia . These findings were driven primarily by clozapine and olanzapine , as treatment with risperidone did not differ from perphenazine on 2 of the 3 statistical methods , whereas treatment with quetiapine or ziprasidone did not significantly differ from perphenazine on any of the 3 statistical methods . Genes ( closed boxes ) shown on the outside of the map are transcribed in a clockwise direction , whereas those on the inside of the map are transcribed counterclockwise . Like SNP genotyping , sequencing of the mitochondrial DNA offers the dual benefits of measuring identity ( across 16,544 bases comprising a large number of polymorphic haplotypes ) as well as stability over passages . Although our approach did not distinguish between the augmenting and augmented antipsychotics , it is important to note that augmentation roles change over time due to prevalent switching of antipsychotics , a phenomenon we captured in analyses with multiple treatment episodes . Thus the calculated incidence rates for transit countries will be too low , while the incidence rates for the final destination countries will be too high . Although this potential bias cannot be ruled out by statistical methods , we attempted to address physicians ' potential preference to switch patients to olanzapine soon after patients ' enrollment in the study . Coronal section 1 shows the globus pallidus , putamen and caudate to have very high DHA concentrations ( > 14.3 % ) , while the surrounding white matter of the coronal radiation is relatively low in DHA ( 5.5 0.9 % ) . In tumors induced by components of the Wnt signaling pathway , a high proportion of cells produce proteins ( Sca-1 , Keratin 6 ) associated with early stages of mammary development , whereas few such cells are observed in tumors induced by activators of Ras signaling [ 9 ] . With over 2 million SNPs already mapped in the human genome , increased density arrays could drop this even further . Because the groups were adjusted age-matched , they were on formula for different periods : the term groups were on formula for 4 weeks , while the preterm groups were on formula for 7.5 weeks . Pfam model PF02517 describes a domain shared by members of the CAAX prenyl protease family , although it is not clear which activity is associated with the domain described . Comparison of the signal intensity and separation angle of all SNPs shows distinct discontinuities over certain chromosomes ( Figure 2 ) .