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It is generally accepted , that what we know today as the Mahayana arose from the Mahasanghikas sect who were the earliest seceders , and the forerunners of the Mahayana . Macro Polo did not visit Sri Lanka specifically to make a pilgrimage to Sri Pada ; he was on a diplomatic mission for Kublai Khan at the time , although he was the earliest European to leave a reasonably accurate account of it . United Provinces of Rio de la Plata , February 2 , 1825 , it was agreed by the latter to prohibit all persons , subject to its jurisdiction , by the most solemn laws , from taking any share in the slave-trade ; and yet it was stated by high authority in the British Parliament , May , 1838 , as a matter of fact , and agreed to afterwards in an address to the Queen , that notwithstanding { 197 } The case of the Amedie ( a ) was the earliest decision in the English courts on the great question touching the legality of the slave-trade , on general principles of international law . a. 1634 , or 5 ( and was the earliest perman . Although 1565 is the earliest date we have for the adjective silent , the descriptive is found applied to people in the late 16th C. Nor can its meaning be considered particularly abstract or learned ; the corresponding noun silence is found extensively in Middle English and Elizabethan English with the meaning muteness , reticence , taciturnity . His catalogue illustrates in great detail the wide range of tools commercially available to watch - and clockmakers in the second half of the 18th century and has the distinction of being the earliest known such catalogue . We will observe samples of thousands of galaxies down to magnitude B = 27.3 with the aim of studying in detail the dwarf galaxy population which , according to hierarchical models of galaxy formation , are the earliest galaxies to form in the universe . Boccaccio shares with Petrarch the honor of being the earliest humanist . Such studies are a vital part of current observational cosmology , these galaxies are observed within a few hundred million years of reionization , are the earliest galaxy-scale systems currently detectable by us in any numbers , and represent the first generation of galaxies ( or certainly one of the first generations ) . In addition , Phase I and Phase II studies ( which are the earliest stages of drug testing in humans ) could be conducted without any FDA review of the investigation . Bullock stated that this was the earliest known incident of alleged plagiarism , shortly after Oberle was hired at the Army lab in 1989 . The portrait is the earliest likeness known of America 's most famous and controversial abolitionist . is the first rhynchosaur reported from the Moenkopi Formation ( Holbrook Member ) , and is the earliest rhynchosaur known from the Americas . This is the earliest manuscript containing Welsh traditional music and the oldest example of music for the harp . This astrolabe , made of cast bronze , is the earliest known dated example and bears the name of its maker . As a tentative result , the village famous for its shamanic activities presents its competitive performances adapted from shamanic rituals , and another village based on its fame of being the earliest Amis tourist center presents a dance as “ tourist dancing mix . Comedonal lesions are the earliest lesions of acne , and closed comedones are the precursor lesion of inflammatory lesions.Mild inflammatory acne is characterized by inflammatory papules and comedones.Moderate inflammatory acne has comedones , inflammatory papules , and pustules . How and where are the earliest magnetic fields made ? The presence of stomata in all plants but the Hepaticophyta suggests that they were the earliest group to diverge .