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Galvus , another drug in the class which is made by Novartis SA , was expected to be approved last year , but U.S. regulators asked for more data , including information about studies linking the drug to skin lesions in monkeys . In this study , they examined the cerebral cortex in monkeys exposed to cocaine during the first , second , or third trimester of pregnancy . Cognitive neuroscience - Activity of locus coeruleus ( LC ) neurons is recorded in monkeys performing an attention task . They found that the cortex was affected only in monkeys exposed to cocaine during the second trimester . In a study conducted in monkeys using brain imaging techniques , researchers found that the environment can modify the animal 's biology as well .