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" From Jo 's diaries we learn that Hopper described this work as a painting of " three characters . This is due to the fact that the large heterogeneity in the employed conditions and the continuous changes in environmental parameters in the often used shake-flask cultures , prevent the unambiguous modeling of the cultivation conditions within the computational framework . We learn this , for example , from the moon , which in daytime appears with so little brightness in the sky , and at night with such brightness that it disperses darkness like the sun or daylight . The more detail you give , the more confusion you will create in your audience ,, you will need commentaries or references to experience , but in your case there is not much of it , and it touches on only a few aspects of the subject you would encompass completely . " " Figures wearing a coat must not let their forms show through so that the coat appears to rest on the flesh ( unless you want to make it appear so ) ; - but you must consider that in between the coat and flesh there are other pieces of clothing which prevent the naked forms of the limbs from appearing or from being visible through the coat . Combined MPE / SHG imaging of tumor explants cultured within 3D collagen gels for eight hours demonstrates that tumor cells reorganize a previously random matrix to facilitate invasion . " A firewall alone simply doesnt provide the level of security most organizations require . Because of your ignorance of the latter , you have only a confused description and can give only a feeble idea of the true form of things ,, you are deluded when you think that you can fully satisfy your audience when it comes to evoking a mass enveloped by a surface .