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Sequence data used to test the statistical accuracy of TBLASTN . The characterization scheme is composed of tests chosen on the basis of comprehensiveness , wide availability , and cost efficiency . Radioactive images were analyzed and quantitated by a phosphoimager . For example , the expression profiles of tumors reflect the transgenic oncogene [ 5 ] ; moreover , those tumors induced by genes that activate the Ras signaling pathway ( for example , polyoma middle T antigen , ErbB2 / Neu , and H-Ras ) are more similar to each other than to tumors induced by components of the Wnt signaling pathway ( Wnt1 , β - catenin , and c-Myc ) with respect both to gene expression patterns ( [ 5 ] , S. Huang et al ., in preparation ) and to cellular composition and histology [ 6-9 ] . We have identified commercial service providers both within and outside the USA , which can perform these analyses , and ATCC and other banks have offered to similarly characterize the lines they maintain . SupplementaryReport.pdf is a PDFfile containing additional information on the statistical analysis of the expression data and the comparison with the cell - line data , as well as detailed descriptions of additional data files 2 and 3 . A second study limitation is the small sample size of the ziprasidone treatment group , which limited the statistical power of the analyses .