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After a thorough review of the limited ethnographic data on shamanic use of the entheogenic mint Salvia divinorum by the Mazatec Indians of the Sierra Madre Oriental of the Mexican state of Oaxaca , with special emphasis on pharmacognostical aspects , the author details the phytochemical studies which led to the isolation of the novel diterpene salvinorin A in 1982-1984 . The list below gives more information on important aspects , both technical and non-technical , that should be taken into account during the planning stage . The emphasis is thus mainly on methodological aspects : The question at this point is not how a specific phenomenon can be modelled , but more general , how ACs with high or even perpetual novelty creation might be constructed . In-house projects can also fail when there is a lack of expertise on particular aspects and an unwillingness to hire consultants to provide such expertise and to educate staff . There will be an emphasis on operational aspects and a majority of sessions will include external speakers , mainly from industry and specialized in the topic of the day .