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And " hard , self-willed , " because it was not only hard against the obedience of God , but also self-willed so as to set upon the Lord . I 'd always had jobs , working hard , during the summer shoveling rocks [ and ] doing hard , difficult , tedious labor type jobs in which people stand over you all day long . Reading the talk here made me realize that in many ways what I tried to offer in the women 's group I led recently was something quite similar to the sense I get in the women 's bookstore - I bought loads of diverse materials and displayed as many as I could cover side out inviting women to pick them up and look - when they did , if they seemed questioning I would tell them a little about what sort of book it was - what might be exciting , hard , sad , happy etc. about it and encouraged women to dip into it , take it home . These lesions are most frequently seen on the thenar and lateral borders of the palms , the base and lateral aspect of the digits , the soles , heels , and toes of the feet.Keratoses may also develop on the dorsum of the hands , the arms , and the legs.Keratoses usually present as small , punctate , nontender , horny , hard , yellowish , often symmetric , cornlike papules.The diameter of the papule ranges from 0.2-1 cm.Lesions may coalesce to form large verrucous plaques.Another type of arsenical keratosis that presents as scaly erythematous or pigmented patches on unexposed body areas is seen in most patients with arsenical cancers.Mees lines on the fingernails are seen in acute and chronic arsenicalism.Causes : A dose-response relationship exists between the amount of arsenic exposure and the frequency of various skin lesions .