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Because just about all colleges and universities use grades as part of a scoring index , if your grades are weak , you 'll need to compensate for this problem by performing at a much higher level on one or more standardized admissions tests . But being unable to do this with safety , he deprived him of his rank , and would not allow him to remain in his Company ; whereat such an enmity arose between the two that no greater or more deadly can be imagined . In addition , there are significant environmental problems in Northeast Asia at a regional level ( transboundary acid rain ) ; environmental problems and management issues that straddle one or more borders ; as well as radical differences in national institutional , economic and technological capabilities with which to respond to national and international regional imperatives . The entity or the entity and a connected entity have an effectively non-contingent obligation to provide a financial benefit to one or more other entities and it is substantially likely that the value provided will be equal to or greater than the value received by the entity . Finally , the word in some circles of DC is that Novak and company did actually disrupt a significant WMD intelligence operation , putting a dozen or more agents out of business , at least , and at serious risk , at worst . The data we do have suggests combination therapy with two or more agents from different classes may delay development of resistance .