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Several circuits have local rules that authorize the office of the clerk to refuse to accept for filing papers that are not in the form required by these rules or by local rules . In contrast , this summers excavations will seek to recover information surrounding the occupation of semi-subterranean pithouses that were also in use during this period . This study , if positive , will provide rationale to examine the role of impaired glucose tolerance in mediating neuropathy . If under local rules the custody of exhibits is left with counsel , the district court should make adequate provision for their preservation during the time during which an appeal may be taken , the prompt deposit with the clerk of such as under Rule 11 ( b ) are to be transmitted to the court of appeals , and the availability of others in the event that the court of appeals should require their transmission . This is not a suitable role for the office of the clerk and the practice exposes litigants to the hazards of time bars ; for these reasons , such rules are proscribed by this rule . ( Any student can declare Anthropology in addition to any current majors or minors by application at the office of Diane Robinson , Recorder of Arts and Sciences , room Tamarack 55 . M. Lee , Ph.D. Study the photic and non-photic signals that entrain circadian and seasonal rhythms and the role of gonadal hormones in the development and adult manifestation of those rhythms . The role of a variety of intracellular signaling molecules including protein and lipid kinases , phosphatases , adapter proteins and transcription factors as potential signal integrators . The original papers will be in the custody of the clerk of the district court at the time the notice of appeal is filed . This study , if positive , will provide rationale for examining the role of oxidative stress in the complications of diabetes , including retinopathy , nephropathy , autonomic neuropathy and wound healing . The custody of exhibits is often the subject of local rules . The role of an amicus should not require the use of a reply brief .