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At the moment , because of an incident that happened a few months ago , it is closed . Yet the piety of the one , though he wills not what God willeth , is more consonant with God 's will than is the impiety of the other , who wills the same thing that God willeth . If , therefore , all the steps taken by the duke be considered , it will be seen that he laid solid foundations for his future power , and I do not consider it superfluous to discuss them , because I do not know what better precepts to give a new prince than the example of his actions ; and if his dispositions were of no avail , that was not his fault , but the extraordinary and extreme malignity of fortune . And firstly , if it be not entirely new , but is , as it were , a member of a state which , taken collectively , may be called composite , the changes arise chiefly from an inherent difficulty which there is in all new principalities ; for men change their rulers willingly , hoping to better themselves , and this hope induces them to take up arms against him who rules : wherein they are deceived , because they afterwards find by experience they have gone from bad to worse . I say at once there are fewer difficulties in holding hereditary states , and those long accustomed to the family of their prince , than new ones ; for it is sufficient only not to transgress the customs of his ancestors , and to deal prudently with circumstances as they arise , for a prince of average powers to maintain himself in his state , unless he be deprived of it by some extraordinary and excessive force ; and if he should be so deprived of it , whenever anything sinister happens to the usurper , he will regain it . For each case who was enrolled , up to three control patients who were lifetime nonsmokers matched on age ( + 5 years ) , sex , race , hospital , and date of interview ( within 2 months ) were interviewed . A PRINCE ought to have no other aim or thought , nor select anything else for his study , than war and its rules and discipline ; for this is the sole art that belongs to him who rules , and it is of such force that it not only upholds those who are born princes , but it often enables men to rise from a private station to that rank . PFT values , on average , than nonexposed children . And it ought to be remembered that there is nothing more difficult to take in hand , more perilous to conduct , or more uncertain in its success , than to take the lead in the introduction of a new order of things . Yet most of the symptomatic responses of the subjects with AHR , though not clinically severe , appeared to be dose-related , which would be difficult to attribute to suggestion . Alexander backwards the Italian potentates ( not only those who have been called potentates , but every baron and lord , though the smallest ) have valued the temporal power very slightly - yet now a king of France trembles before it , and it has been able to drive him from Italy , and to ruin the Venetians - although this may be very manifest , it does not appear to me superfluous to recall it in some measure to memory . Firstly , he did not see his way to make him master of any state that was not a state of the Church ; and if he was willing to rob the Church he knew that the Duke of Milan and the Venetians would not consent , because Faenza and Rimini were already under the protection of the Venetians . For whenever these factions have their cardinals they do not remain quiet for long , because cardinals foster the factions in Rome and out of it , and the barons are compelled to support them , and thus from the ambitions of prelates arise disorders and tumults among the barons . Changes in physical properties are mostly gradual downhole , with the exception of those properties that are sensitive to the major lithologic and compositional changes that occur at the lithologic Unit I / Unit II boundary ( 40.6 mbsf ) , at the diatom mat ( 111-115 mbsf ) , and ~ 40-45 m above basement ( at ~ 205 to 210 mbsf ) , below which the occurrence of chert and glauconite increase . Among children of nonsmoking parents who enrolled after July 1986 , the asthma severity score was not significantly different , but both FEV1 and FEF25-75 were increased , though less so than among the children of smoking parents .