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Insert , SEM cross section of the shell , revealing the calcitic prismatic layer ( c / pr ) and the inner aragonitic nacreous layer ( a / nc ) . Finally , there was no evidence of an increased risk associated with naproxen use and our results are more compatible with a minor reduced risk of MI . Support for this hypothesis comes from randomized double-blind trials of clozapine versus olanzapine [ 38,39 ] , in which the treatment groups did not significantly differ on dropout rates , possibly because the double-blind design required both treatment groups to undergo regular monitoring with blood tests . Importantly , it produces for genes of interest an average number of high confidence putative partners that is in the range of standard experimental validation techniques . Larger wounds in Pax6 + / - corneal epithelia healed faster than smaller wounds ( presumably because larger wounds were closer to the source of proliferating limbal stem cells ) , and extrapolation from figure 2 in that study [ 59 ] suggested that wounds smaller than 500 μ m in diameter would heal more slowly than wild-type . Using each profile-positive genome in turn , we scored every protein in that genome for its correlation between a phylogenetic profile and the list of related sequences in other genomes as measured by BLAST comparison . ( D ) Median Z-scores for each motif in each of the subnet ensembles and the Z-score of the motif in the full network . The average number of candidates produced by CLOE for each analyzed protein was approximately 17 , which represents a strong reduction if compared to the single organism approach ( 746 and 375 for the human and mouse datasets , respectively ) . In the Somali culture khat has a special significance , which also comes from existing traditional knowledge about its dangers . Therefore we suppose that retrospective assessment of khat intake is more valid than that of food intake . Of 3332 patients who met the minimal inclusion criteria noted above , 2327 ( 69.8 % ) enrolled , 765 ( 23.0 % ) refused , and 240 ( 7.2 % ) were not enrolled due to other reasons . The work presented here is part of efforts to create a database of the properties of each line and to identify a reference standard for comparisons between laboratories . In parallel , the human dataset was ranked for each human EST , and lists of candidates corresponding to the top 1 % ranks where obtained ( Single organism ) . During the six-year period , the S. Enteritidis incidence rate among travellers to Spain and Turkey appeared to decline . This contrasts sharply with the report by D'Cruz et al. [ 3 ] of mutations affecting mostly K-Ras and also N-Ras , but never H-Ras , in mouse mammary tumors induced by an MMTV-c-Myc transgene . The legend presents the results of Duncan 's multiple range test ; regional DHA means that are not significantly different share a common line . As described above , in the whole-eye culture system , the corneal epithelial migration is modulated by the presence of an inflamed stroma , which would be expected to accelerate cell migration over extended periods of healing . From the boxplots it is apparent that with decreasing subnet size the clustering coefficient will tend to decrease , reflecting the increasingly sparse network with a correlated structure . The method consists in ranking EST probes in the datasets of the two species according to the similarity of their expression profiles with that of two EST probes from orthologous genes , and extracting orthologous EST pairs from a given top interval of the ranked lists .