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This question has been the center of a debate that has been raging among the scientific community ever since Nancy Wertheimer and her colleague Ed Leeper reported an increased incidence of childhood leukemia , lymphomas , and nervous system tumors in Denver Colorado in 1979 . One would think , from looking at literature , that this question had never disturbed a solitary individual 's musings . The answer to this question has to do with the the stratospheric clouds that often form over Antarctica and the chemical cycle that destroys ozone . In Rome this question had long been settled . This question has been much discussed in our days . The practical results of United Nations action on this question have so far been disappointing . This question had proven controversial at MOP-1 , in particular the use of trade sanctions as a possible compliance measure . Maria Michela Sassi 's exploration of this question has now been translated into English . The department 's representative argued that the manner in which this question had been constructed meant that candidates had to be able to assess and assimilate a large quantity of material before they could even realistically think of answering the question . Several points mentioned by BESSER and several others on this question have a much greater impact on those who are concerned with cataloguing and the networking of bibliographic information , as well as preservation itself . This question has been addressed by other means .