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Proposed mechanisms for the induction of a prothrombotic state by tumor cells include ( 1 ) the expression of a tissue factor , an activator of the extrinsic clotting pathway ; ( 2 ) the release of a tumor-derived cysteine proteinase , the so-called cancer procoagulant , which directly activates factor X independent of factor VII ; ( 3 ) the induction of a state of relative resistance to activated protein C ; ( 4 ) the direct activation of platelets by fragments of tumor cell membranes ; and ( 5 ) the indirect effects of tumor-derived or tumor-induced cytokines on the expression of tissue factor , thrombomodulin , and other factors . Originating many tens of miles beneath the ground , magma commonly contains some crystals , fragments of surrounding ( unmelted ) rocks , and dissolved gases , but it is primarily a liquid composed principally of oxygen , silicon , aluminum , iron , magnesium , calcium , sodium , potassium , titanium , and manganese . Aside from beads , some sewn to leather , fragments of bracelets made from the shells of gastropods ( probably conch ) from the Red Sea were found , as well as pieces of the characteristic Nubian black incised ware , which eventually mended to create a complete vessel . It also contains revisions and draft fragments of works discussed in accompanying correspondence . Specialists in the Sector for Restoration of Ceramics , Glass and Porcelain work at solving tasks relating to the restoration and reconstruction from numerous fragments of works of applied art dating as far back as antiquity and up to the present day . Notes : Discusses 1981 excavations on Mulberry Row , particularly the fragments of animal bones found outside the doorway of a building used originally to store nail rod but later apparently for human occupation and the contents of a dry well or deep cellar dug near the original kitchen yard .