tokens: Employing fluorescence spectroscopy and circular dichroism , we showed that the binding of Ca2+ to ALG-2 induced significant conformational changes in both the N-terminal and C-terminal domains of the protein .
folded_tokens: employ fluorescence spectroscopy and circular dichroism , we show that the binding of ca2+ to alg-2 induce significant conformational change in both the n-terminal and c-terminal domain of the protein .