tokens: During treatment , the phosphorylation state of Rb shifted to a hypophosphorylated form . mRNA for the HPV E6 / E7 genes decreased ; however , significant changes in the E7 protein were not observed , while increased levels of Rb immunoprecipitated with anti E7 antibodies were observed .
folded_tokens: during treatment , the phosphorylation state of rb shift to a hypophosphorylate form . mrna for the hpv e6 / e7 gene decrease ; however , significant change in the e7 protein be not observe , while increase level of rb immunoprecipitate with anti e7 antibody be observe .