tokens: It has been demonstrated previously that Pax-6 , a paired domain ( PD ) / homeodomain ( HD ) transcription factor critical for eye development , contributes to the activation of the alphaB - , alphaA - , delta1 - , and zeta-crystallin genes in the lens .
folded_tokens: it have be demonstrate previously that pax-6 , a paired domain ( pd ) / homeodomain ( hd ) transcription factor critical for eye development , contribute to the activation of the alphab - , alphaa - , delta1 - , and zeta-crystallin gene in the lens .