tokens: Expression of various FAK mutants in the FAK- cells showed that FAK kinase activity , the Tyr-397 / SH2 domain binding site , and the first proline rich SH3 binding region in the FAK C-terminal domain were individually needed to promote full FAK mediated FAK- cell migration to FN whereas direct paxillin binding to FAK was not required .
folded_tokens: expression of various fak mutant in the fak-_NN cell show that fak kinase activity , the tyr-397 / sh2 domain bind site , and the first proline rich sh3 binding region in the fak c-terminal domain be individually need to promote full fak mediate fak- cell migration to fn whereas direct paxillin binding to fak be not require .