tokens: CONCLUSION : In Cdks functioning throughout the cell cycle , tyrosine phosphorylation is inhibitory to the activation of kinase , whereas the phosphorylation of threonine in the T-loop is essential for activation .
folded_tokens: conclusion : in cdk function throughout the cell cycle , tyrosine phosphorylation be inhibitory to the activation of kinase , whereas the phosphorylation of threonine in the t-loop be essential for activation .