tokens: In contrast , c-Src activated by isoproterenol led to tyrosine phosphorylation of Shc and subsequent Erk activation , but not tyrosine phosphorylation of cortactin or Stat3 .
folded_tokens: in contrast , c-src activate by isoproterenol lead to tyrosine phosphorylation of shc and subsequent erk activation , but not tyrosine phosphorylation of cortactin or stat3 .