tokens: However , while IL-1beta and TNF-alpha both induced nuclear binding of the Rel proteins p50 and p65 to an NF-kappaB consensus oligonucleotide in gel shift assays and caused transient degradation of inhibitor of NF-kappaB-alpha ( IkappaB-alpha ) in the cytoplasm of myofibroblasts , only IL-1beta upregulated PDGF-Ralpha .
folded_tokens: however , while il-1beta and tnf-alpha both induce nuclear binding of the rel protein p50 and p65 to a nf-kappab consensus oligonucleotide in gel shift assay and cause transient degradation of inhibitor of nf-kappab-alpha ( ikappab-alpha ) in the cytoplasm of myofibroblast , only il-1beta upregulate pdgf-ralpha .