tokens: Stoichiometric phosphorylation of human p53 at Ser315 stimulates p53 dependent transcription . p53 protein activity as a transcription factor can be activated in vivo by antibodies that target its C-terminal negative regulatory domain suggesting that cellular enzymes that target this domain may play a role in stimulating p53 dependent gene expression .
folded_tokens: stoichiometric phosphorylation of human p53 at ser315 stimulate p53 dependent transcription . p53 protein activity as a transcription factor can be activate in vivo by antibody that target its c-terminal negative regulatory domain suggest that cellular enzyme that target this domain may play a role in stimulate p53 dependent gene expression .