tokens: However , changing the half-site to the consensus sequence AGGTCA ( IRper-1 ) increased binding of AaEcR.AaUSP 10-fold over IRhsp-1 and , at the same time , reduced the stringency of the spacer length requirement , with IRper-0 to IRper-5 showing detectable binding .
folded_tokens: however , change the half-site to the consensus sequence aggtca ( irper-1 ) increase binding of aaecr.aausp 10-fold over irhsp-1 and , at the same time , reduce the stringency of the spacer length requirement , with irper-0 to irper-5 show detectable binding .