tokens: Although we predicted that overexpression of the COOH-terminal domains , which were thought to be involved in the regulation of SREBP processing , would result in disruption of the SREBP dependent transcriptional regulation of several genes , the mRNA levels for 3-hydroxy-3-methylglutaryl coenzyme A ( HMG CoA ) synthase in these two cell lines were regulated in a sterol dependent manner .
folded_tokens: although we predict that overexpression of the cooh-terminal domain , which be think to be involve in the regulation of srebp processing , would result in disruption of the srebp dependent transcriptional regulation of several gene , the mrna level for 3-hydroxy-3-methylglutaryl coenzyme a ( hmg coa ) synthase in these two cell line be regulate in a sterol dependent manner .