tokens: RXR-gamma expression produced significant reduction in levels of RA responsive genes including the cyclin dependent kinase inhibitors p21Cip1 / WAF1 and p27Kip1 , resulting in increased cdc2 and cdk2 kinase activity and RB phosphorylation .
folded_tokens: rxr-gamma expression produce significant reduction in level of ra responsive gene include the cyclin dependent kinase inhibitor p21cip1 / waf1 and p27kip1 , result in increase cdc2 and cdk2 kinase activity and rb phosphorylation .