tokens: Its cognate binding protein , REST / NRSF , is an essential transcription factor ; its null mutations result in embryonic lethality , and its dominant negative mutants produce aberrant expression of neuron specific genes .
folded_tokens: its cognate binding protein , rest / nrsf , be a essential transcription factor ; its null mutation result in embryonic lethality , and its dominant negative mutant produce aberrant expression of neuron specific gene .