tokens: D-cyclin-cdk activity is required for Rb phosphorylation in v-Jun transformed cells , since ectopic expression of the cdk4- and cdk6 specific inhibitor p16 ( INK4A ) inhibits both DNA synthesis and cell proliferation .
folded_tokens: d-cyclin-cdk activity be require for rb phosphorylation in v-jun transform cell , since ectopic expression of the cdk4-_NN and cdk6 specific inhibitor p16 ( ink4a ) inhibit both dna synthesis and cell proliferation .