tokens: Moreover , this enhancement of transcriptional activation by COUP-TFI requires specifically the AF-1 transactivation function of ER and can be observed in the presence of E2 or 4-hydroxytamoxifen but not ICI 164384 .
folded_tokens: moreover , this enhancement of transcriptional activation by coup-tfus require specifically the af-1 transactivation function of er and can be observe in the presence of e2 or 4-hydroxytamoxifen but not ici 164384 .