tokens: Substitution of the Ser-Thr sites with the phosphomimetic Asp generated a constitutively active form of IRF-3 that functioned as a very strong activator of promoters containing PRDI-PRDIII or ISRE regulatory elements .
folded_tokens: substitution of the Ser-Thr site with the phosphomimetic asp generate a constitutively active form of irf-3 that function as a very strong activator of promoter contain prdi-prdiius or isre regulatory element .