tokens: We demonstrated that , under serum starved conditions , KMS-11 and OPM-2 cells express appreciable levels of phosphorylated FGFR3 mutants indicating a constitutive activation of the Y373C and K650E receptors ; the addition of the aFGF ligand further increased the level of receptor phosphorylation .
folded_tokens: we demonstrate that , under serum starve condition , kms-11 and opm-2 cell express appreciable level of phosphorylate fgfr3 mutant indicate a constitutive activation of the y373c and k650e receptor ; the addition of the afgf ligand further increase the level of receptor phosphorylation .