tokens: To determine whether interaction of arsenite with the hormone binding domain results in receptor activation , COS-1 cells were transiently cotransfected with the chimeric receptors GAL-ER , which contains the hormone binding domain of ERalpha and the DNA binding domain of the transcription factor GAL4 , and a GAL4 responsive CAT reporter gene .
folded_tokens: to determine whether interaction of arsenite with the hormone binding domain result in receptor activation , cos-1 cell be transiently cotransfect with the chimeric receptor gal-er , which contain the hormone binding domain of eralpha and the dna binding domain of the transcription factor gal4 , and a gal4 responsive cat reporter gene .