tokens: Members of the JAK / Tyk family of tyrosine kinases mediate phosphorylation of STAT3 at Tyr705 during CNTF signaling ; however , the kinase responsible for phosphorylation at STAT3 Tyr727 appears to depend on both the extracellular stimulus and the cellular context .
folded_tokens: member of the jak / Tyk family of tyrosine kinase mediate phosphorylation of stat3 at tyr705 during cntf signaling ; however , the kinase responsible for phosphorylation at stat3 tyr727 appear to depend on both the extracellular stimulus and the cellular context .