tokens: Much evidence indicates that p38 is an activator of MyoD : ( i ) p38 kinase activity is required for the expression of MyoD responsive genes , ( ii ) enforced induction of p38 stimulates the transcriptional activity of a Gal4-MyoD fusion protein and allows efficient activation of chromatin integrated reporters by MyoD , and ( iii ) MyoD dependent myogenic conversion is reduced in mouse embryonic fibroblasts derived from p38alpha (-/- ) embryos .
folded_tokens: much evidence indicate that p38 be a activator of myod : ( i ) p38 kinase activity be require for the expression of myod responsive gene , ( ii ) enforce induction of p38 stimulate the transcriptional activity of a gal4-myod fusion protein and allow efficient activation of chromatin integrate reporter by myod , and ( iii ) myod dependent myogenic conversion be reduce in mouse embryonic fibroblast derive from p38alpha (-/- ) embryo .