tokens: The decrease of TNF receptors by IL-4 was accompanied by down-regulation of TNF induced activities , including cytotoxicity , caspase-3 activation , NF-kappaB and AP-1 activation , and c-Jun N-terminal kinase induction .
folded_tokens: the decrease of tnf receptor by il-4 be accompany by down-regulation of tnf induce activity , include cytotoxicity , caspase-3 activation , nf-kappab and ap-1 activation , and c-jun n-terminal kinase induction .