tokens: Because GH induced Akt activation was completely inhibited in both cells by the same concentration of LY294002 , these findings indicate that the wortmannin sensitivity of both the IRS-1 independent and -dependent GH induced MAP kinase activation may reflect the activity of another wortmannin sensitive target ( s ) in addition to PI3K in mediation of GH induced MAP kinase activation in these cells .
folded_tokens: because gh induce akt activation be completely inhibit in both cell by the same concentration of ly294002 , these finding indicate that the wortmannin sensitivity of both the irs-1 independent and -dependent gh induce map kinase activation may reflect the activity of another wortmannin sensitive target ( s ) in addition to pi3k in mediation of gh induce map kinase activation in these cell .