tokens: Elimination of ETH1 in apn1 strains also increased spontaneous mutation rates 9- or 31-fold compared to the wild type as determined by reversion to adenine or lysine prototrophy , respectively .
folded_tokens: elimination of eth1 in apn1 strain also increase spontaneous mutation rate 9- or 31-fold compare to the wild type as determine by reversion to adenine or lysine prototrophy , respectively .