tokens: Here we have therefore examined the effect of the phorbol ester PMA ( phorbol 12-myristate 13-acetate ) which stimulates PKC and a combination of the adenosine receptor agonist NECA ( 5'- ( N-ethyl ) -carboxamido adenosine ) and forskolin to raise cAMP , on the levels of c-Fos and Jun and on the binding and transcriptional activity of the transcription factor , activator protein-1 ( AP-1 ) .
folded_tokens: here we have therefore examined the effect of the phorbol ester pma ( phorbol 12-myristate 13-acetate ) which stimulates pkc and a combination of the adenosine receptor agonist neca ( 5'- ( n-ethyl ) -carboxamido adenosine ) and forskolin to raise camp , on the levels of c-fos and jun and on the binding and transcriptional activity of the transcription factor , activator protein-1 ( ap-1 ) .
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