Challenges in developing new therapeutic strategies include not only identifying novel agents , but also improving the definitions of clinical endpoints and defining efficacy at the biologic level .
challenges in developing new therapeutic strategies include not only identifying novel agents , but also improving the definitions of clinical endpoints and defining efficacy at the biologic level .
O O O O B-other_name I-other_name O O O O O O O O O O O O O O O O O O O O O O O