In each case the allele loss was caused by an interstitial deletion because heterozygosity at distal markers was retained and because quantitative Southern blotting demonstrated hemizygosity .
in each case the allele loss was caused by an interstitial deletion because heterozygosity at distal markers was retained and because quantitative southern blotting demonstrated hemizygosity .
O O O O B-other_name I-other_name O O O O O O O O O B-DNA_domain_or_region I-DNA_domain_or_region O O O O O B-other_name I-other_name O B-other_name O