Other steroid receptor drugs such as Raloxifene , RU486 , or the ICI 182 , 780 in PMA-differentiated cells displayed agonist activity by preventing TNF-alpha -induced apoptosis as efficiently as the hormones alone , providing further evidence to the notion that steroid receptor drugs may manifest agonist or antagonist activities depending on the cellular context in which they are studied .
other steroid receptor drugs such as raloxifene , ru486 , or the ici 182 , 780 in pma-differentiated cells displayed agonist activity by preventing tnf-alpha -induced apoptosis as efficiently as the hormones alone , providing further evidence to the notion that steroid receptor drugs may manifest agonist or antagonist activities depending on the cellular context in which they are studied .
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