We show here that c-Raf , which is at the helm of the classic MAP- Erk cascade , contributes to IL-2 induction through a distal enhancer element spanning the nucleotides from positions -502 to -413 in front of the transcriptional start site of the IL-2 gene .
we show here that c-raf , which is at the helm of the classic map- erk cascade , contributes to il-2 induction through a distal enhancer element spanning the nucleotides from positions -502 to -413 in front of the transcriptional start site of the il-2 gene .
O O O O B-protein_molecule O O O O O O O O O B-other_name B-protein_molecule O O O O B-protein_molecule O O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O O O O O O O O O O O O O O O O O B-protein_molecule O O