An increase in the intracellular Ca2+ concentration is both necessary and sufficient for Rap1 activation since it was induced by agents that increase intracellular Ca2+ and inhibited by a Ca2+ -chelating agent .
an increase in the intracellular ca2+ concentration is both necessary and sufficient for rap1 activation since it was induced by agents that increase intracellular ca2+ and inhibited by a ca2+ -chelating agent .
O O O O B-other_name B-atom O O O O O O O B-protein_molecule O O O O O O O O O B-atom B-atom O O O O B-atom O O O