However , in the presence of PML-RAR , the synthetic retinoid is a much better transactivator of retinoic acid -responsive element-containing promoters than the natural retinoid , whereas , in the presence of RAR alpha , AM580 and ATRA have similar activity .
however , in the presence of pml-rar , the synthetic retinoid is a much better transactivator of retinoic acid -responsive element-containing promoters than the natural retinoid , whereas , in the presence of rar alpha , am580 and atra have similar activity .
O O O O O O B-protein_molecule O O B-other_organic_compound I-other_organic_compound O O O O O O B-other_organic_compound I-other_organic_compound O O O O O B-other_organic_compound I-other_organic_compound O O O O O O O B-protein_molecule I-protein_molecule O B-other_organic_compound O B-other_organic_compound O O O O