Mutations in this DNA-binding site abolished binding of a nuclear factor in human B cell nuclear extract and decreased the activity of the DR alpha promoter to a basal level .
mutations in this dna-binding site abolished binding of a nuclear factor in human b cell nuclear extract and decreased the activity of the dr alpha promoter to a basal level .
O O O B-DNA_domain_or_region I-DNA_domain_or_region O O O O B-protein_family_or_group I-protein_family_or_group O B-cell_component I-cell_component I-cell_component I-cell_component I-cell_component O O O O O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O O B-other_name I-other_name O