To delineate the effects of these motifs on the replicative capacity of HIV and to explore the possibility of extending the virus host range , known heterologous enhancer/promoters were inserted into the HIV-1 LTR in place of the NF-kappa B and Sp1 binding sites .
to delineate the effects of these motifs on the replicative capacity of hiv and to explore the possibility of extending the virus host range , known heterologous enhancer/promoters were inserted into the hiv-1 ltr in place of the nf-kappa b and sp1 binding sites .
O O O O O O O O O O O O B-virus O O O O O O O O O O O O O B-DNA_domain_or_region I-DNA_domain_or_region O O O O B-DNA_domain_or_region I-DNA_domain_or_region O O O O B-protein_molecule I-protein_molecule O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O