The immunosuppressants ciclosporin and FK506 block the Ca ( 2+ ) -dependent signal-transduction pathway emanating from the T-cell receptor , thereby inhibiting the activation of helper T cells .
the immunosuppressants ciclosporin and fk506 block the ca ( 2+ ) -dependent signal-transduction pathway emanating from the t-cell receptor , thereby inhibiting the activation of helper t cells .
O B-other_name B-other_organic_compound O B-other_organic_compound O O B-other_name I-other_name I-other_name I-other_name I-other_name I-other_name I-other_name O O O B-protein_family_or_group I-protein_family_or_group O O O O O O B-cell_type B-cell_type I-cell_type O