In contrast , prostaglandin I2 ( PGI2 ) , a strong negative regulator of platelet function , inhibited agonist-induced as well as Ca2+ -induced activation of Rap1 .
in contrast , prostaglandin i2 ( pgi2 ) , a strong negative regulator of platelet function , inhibited agonist-induced as well as ca2+ -induced activation of rap1 .
O O O B-other_organic_compound I-other_organic_compound O B-other_organic_compound O O O O O O O B-cell_type O O O O O O O B-atom O O O B-protein_molecule O