The modulation by anti- LPS mAbs of mCD14 -mediated LPS uptake was associated with inhibition of LPS -induced nuclear factor-kappaB ( NF-kappaB ) translocation and TNF-alpha secretion in CHO-CD14 cells and monocytes , respectively , while mAb enhancement of non- mCD14 -mediated LPS uptake stimulated these activities .
the modulation by anti- lps mabs of mcd14 -mediated lps uptake was associated with inhibition of lps -induced nuclear factor-kappab ( nf-kappab ) translocation and tnf-alpha secretion in cho-cd14 cells and monocytes , respectively , while mab enhancement of non- mcd14 -mediated lps uptake stimulated these activities .
O O O B-protein_family_or_group B-lipid O O B-protein_molecule O B-lipid O O O O O O B-lipid O O O O B-protein_complex O O O B-protein_molecule O O B-cell_line I-cell_line O O O O O O O O O B-other_name B-protein_molecule O B-lipid O O O O O