Introduction of point mutations suppressing GABP binding to the DSE interfered with the induction of the distal enhancer and the entire IL-2 promoter-enhancer , while overexpression of both GABP factors enhanced the IL-2 promoter-enhancer induction .
introduction of point mutations suppressing gabp binding to the dse interfered with the induction of the distal enhancer and the entire il-2 promoter-enhancer , while overexpression of both gabp factors enhanced the il-2 promoter-enhancer induction .
O O B-other_name I-other_name O O O O O B-DNA_domain_or_region O O O O O O B-DNA_domain_or_region I-DNA_domain_or_region O O O B-protein_molecule O O O O O O B-protein_family_or_group I-protein_family_or_group O O B-protein_molecule O O O