When mutations that abolished factor binding in bandshift assays were introduced into a Wp reporter construct , the loss of any one of the three UAS1 binding sites was sufficient to reduce promoter activity by 10- to 30-fold in B cells .
when mutations that abolished factor binding in bandshift assays were introduced into a wp reporter construct , the loss of any one of the three uas1 binding sites was sufficient to reduce promoter activity by 10- to 30-fold in b cells .
O O O O O O O B-other_name I-other_name O O O O B-DNA_molecule I-DNA_molecule I-DNA_molecule O O O O O O O O O B-DNA_domain_or_region B-DNA_domain_or_region I-DNA_domain_or_region O O O O B-other_name I-other_name O O O O O B-cell_type I-cell_type O