We show here that AM580 , a stable retinobenzoic derivative originally synthesized as a RAR alpha agonist , is a powerful inducer of granulocytic maturation in NB4 , an APL -derived cell line , and in freshly isolated APL blasts .
we show here that am580 , a stable retinobenzoic derivative originally synthesized as a rar alpha agonist , is a powerful inducer of granulocytic maturation in nb4 , an apl -derived cell line , and in freshly isolated apl blasts .
O O O O B-other_organic_compound O O O B-other_organic_compound I-other_organic_compound O O O O B-protein_molecule I-protein_molecule O O O O O O O B-other_name I-other_name O B-cell_line O O B-other_name O O O O O O B-cell_type I-cell_type I-cell_type I-cell_type O