tokens: After treatment of APL cells with AM580 either alone or in combination with granulocyte colony-stimulating factor ( G-CSF ) , the compound induces granulocytic maturation , as assessed by determination of the levels of leukocyte alkaline phosphatase , CD11b , CD33 , and G-CSF receptor mRNA , at concentrations that are 10- to 100-fold lower than those of ATRA necessary to produce similar effects .
folded_tokens: after treatment of apl cells with am580 either alone or in combination with granulocyte colony-stimulating factor ( g-csf ) , the compound induces granulocytic maturation , as assessed by determination of the levels of leukocyte alkaline phosphatase , cd11b , cd33 , and g-csf receptor mrna , at concentrations that are 10- to 100-fold lower than those of atra necessary to produce similar effects .
labels: O O O B-cell_line I-cell_line O B-other_organic_compound O O O O O O B-protein_molecule I-protein_molecule I-protein_molecule O B-protein_molecule O O O O O B-other_name I-other_name O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O B-other_organic_compound O O O O O O