These data indicate that IL-11 is a regulatory cytokine in the lung and that , like other members of this family , its anti-inflammatory properties appear to be linked to its suppression of NF-kappaB activation , diminished production of TNF-alpha , and reduced up-regulation of lung vascular ICAM-1 .
these data indicate that il-11 is a regulatory cytokine in the lung and that , like other members of this family , its anti-inflammatory properties appear to be linked to its suppression of nf-kappab activation , diminished production of tnf-alpha , and reduced up-regulation of lung vascular icam-1 .
O O O O B-protein_molecule O O B-protein_family_or_group B-protein_family_or_group O O B-body_part O O O O O O O O O O O B-other_name I-other_name O O O O O O O O B-protein_complex O O O O O B-protein_molecule O O O O O B-protein_molecule I-protein_molecule I-protein_molecule O