However , transactivation of the CD4 promoter by ORFs U86 and U89 is independent of the CRE element , suggesting that additional HHV-6 ORFs are likely to contribute to CD4 gene activation .
however , transactivation of the cd4 promoter by orfs u86 and u89 is independent of the cre element , suggesting that additional hhv-6 orfs are likely to contribute to cd4 gene activation .
O O O O O B-DNA_domain_or_region I-DNA_domain_or_region O B-DNA_family_or_group B-DNA_domain_or_region O B-DNA_domain_or_region O O O O B-DNA_domain_or_region I-DNA_domain_or_region O O O O B-virus O O O O O O B-DNA_domain_or_region I-DNA_domain_or_region O O