The ability of E2A-HLF to prolong the survival of interleukin-3 ( IL-3 ) -dependent murine pro-B cells after IL-3 withdrawal suggests that it disrupts signaling pathways normally responsible for cell suicide , allowing the cells to accumulate as transformed lymphoblasts .
the ability of e2a-hlf to prolong the survival of interleukin-3 ( il-3 ) -dependent murine pro-b cells after il-3 withdrawal suggests that it disrupts signaling pathways normally responsible for cell suicide , allowing the cells to accumulate as transformed lymphoblasts .
O O O B-protein_molecule O O O O O B-protein_molecule O B-protein_molecule O O O O O O B-protein_molecule O O O O O B-other_name I-other_name O O O B-other_name I-other_name O O O O O O O B-cell_type I-cell_type O