When this membrane-proximal TRAF6 interaction domain was deleted , RANK -mediated NF-kappaB signaling was completely inhibited while c-Jun NH2-terminal kinase activation was partially inhibited .
when this membrane-proximal traf6 interaction domain was deleted , rank -mediated nf-kappab signaling was completely inhibited while c-jun nh2-terminal kinase activation was partially inhibited .
O O B-protein_domain_or_region B-protein_molecule O O O O O B-protein_molecule O B-protein_complex O O O O O B-protein_molecule I-protein_molecule I-protein_molecule O O O O O