We have shown that 1- ( 5-chloronaphthalene-1-sulfonyl ) -1H-hexahydro-1 , 4-diazepine hydrochloride ( ML-9 ) , an inhibitor of myosin light chain kinase , induces differentiation of monocytoid leukemia cell lines U937 and THP-1 but not of myeloblastic leukemic ML-1 cell or erythroleukemia K562 cells .
we have shown that 1- ( 5-chloronaphthalene-1-sulfonyl ) -1h-hexahydro-1 , 4-diazepine hydrochloride ( ml-9 ) , an inhibitor of myosin light chain kinase , induces differentiation of monocytoid leukemia cell lines u937 and thp-1 but not of myeloblastic leukemic ml-1 cell or erythroleukemia k562 cells .
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