To further analyze potential cross points between positively and negatively regulating signaling pathways in T cells , we tested the effects of activators of the adenylate cyclase or PKA on two parallel mitogen-activated protein kinase signaling pathways mediated by extracellular signal-regulated kinase ( ERK ) and c-Jun N-terminal kinase .
to further analyze potential cross points between positively and negatively regulating signaling pathways in t cells , we tested the effects of activators of the adenylate cyclase or pka on two parallel mitogen-activated protein kinase signaling pathways mediated by extracellular signal-regulated kinase ( erk ) and c-jun n-terminal kinase .
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