In this syndrome , tumorigenesis classically initiates from an inherited mutation in one allele followed by somatic deletion of the normal allele .
in this syndrome , tumorigenesis classically initiates from an inherited mutation in one allele followed by somatic deletion of the normal allele .
O O O O O O O O O B-other_name I-other_name O O B-DNA_domain_or_region O O B-other_name I-other_name O O B-DNA_domain_or_region I-DNA_domain_or_region O