Dexamethasone markedly inhibited LPS -stimulated accumulation of mRNA for ELAM-1 and expression of ELAM-1 and ICAM-1 ( IC50 < 10 nM , both P < 0 . 001 , n = 4-9 ) ; inhibition of expression by dexamethasone was reversed by RU-486 ( both P < 0 . 005 , n = 4-6 ) .
dexamethasone markedly inhibited lps -stimulated accumulation of mrna for elam-1 and expression of elam-1 and icam-1 ( ic50 < 10 nm , both p < 0 . 001 , n = 4-9 ) ; inhibition of expression by dexamethasone was reversed by ru-486 ( both p < 0 . 005 , n = 4-6 ) .
O O O B-lipid O O O O O B-protein_molecule O O O B-protein_molecule O B-protein_molecule O O O O O O O O O O O O O O O O O O O O O O B-lipid O O O B-other_organic_compound O O O O O O O O O O O O O