Previous studies have shown constitutive activation of IL-4 and IL-7 signaling pathways , as measured by activation of Janus protein kinase ( JAK ) 1 , JAK3 , STAT5 , and STAT6 , in pre-B cells transformed by v-Abl .
previous studies have shown constitutive activation of il-4 and il-7 signaling pathways , as measured by activation of janus protein kinase ( jak ) 1 , jak3 , stat5 , and stat6 , in pre-b cells transformed by v-abl .
O O O O O O O B-protein_molecule O B-protein_molecule O O O O O O O O B-protein_molecule I-protein_molecule I-protein_molecule I-protein_molecule I-protein_molecule I-protein_molecule I-protein_molecule O B-protein_molecule O B-protein_molecule O O B-protein_molecule O O B-cell_type I-cell_type O O B-protein_molecule O