The activation of T cells requires engagement of the T cell receptor/CD3 complex and co-stimulatory molecules , and results in the triggering of several signaling pathways which lead rapidly to the nuclear translocation of several transcription factors , such as nuclear factor ( NF ) -kappa B and NF-AT .
the activation of t cells requires engagement of the t cell receptor/cd3 complex and co-stimulatory molecules , and results in the triggering of several signaling pathways which lead rapidly to the nuclear translocation of several transcription factors , such as nuclear factor ( nf ) -kappa b and nf-at .
O O O B-cell_type I-cell_type O O O O B-protein_complex I-protein_complex I-protein_complex I-protein_complex O B-protein_family_or_group I-protein_family_or_group O O O O O O O O B-other_name I-other_name O O O O O B-other_name I-other_name O O B-protein_family_or_group I-protein_family_or_group O O O B-protein_complex I-protein_complex I-protein_complex I-protein_complex I-protein_complex I-protein_complex I-protein_complex O B-protein_family_or_group O