Fab fragment of anti- E . chaffeensis immunoglobulin G complexed with E . chaffeensis did not induce any of these three cytokines , indicating that ehrlichial binding is required for IL-1beta mRNA expression and that binding of the immune complex to the Fc gamma receptor is required for TNF-alpha and IL-6 mRNA expression and enhanced IL-1beta mRNA expression .
fab fragment of anti- e . chaffeensis immunoglobulin g complexed with e . chaffeensis did not induce any of these three cytokines , indicating that ehrlichial binding is required for il-1beta mrna expression and that binding of the immune complex to the fc gamma receptor is required for tnf-alpha and il-6 mrna expression and enhanced il-1beta mrna expression .
O O O B-protein_molecule B-mono_cell I-mono_cell I-mono_cell O O O O B-mono_cell I-mono_cell I-mono_cell O O O O O O O O O O O O O O O O B-protein_molecule O O O O O O O B-protein_complex I-protein_complex O O B-protein_family_or_group I-protein_family_or_group I-protein_family_or_group O O O B-protein_molecule O B-protein_molecule O O O O B-protein_molecule O O O