In this report we show that the functional synergy between IL-12 and IL-2 in CD8+CD18bright T cells correlates with the activation of the stress kinases , p38 mitogen-activated protein ( MAP ) kinase and stress-activated protein kinase ( SAPK ) /Jun N-terminal kinase , but not with the activation of the extracellular signal-regulated kinases .
in this report we show that the functional synergy between il-12 and il-2 in cd8+cd18bright t cells correlates with the activation of the stress kinases , p38 mitogen-activated protein ( map ) kinase and stress-activated protein kinase ( sapk ) /jun n-terminal kinase , but not with the activation of the extracellular signal-regulated kinases .
O O O O O O O O O O B-protein_molecule O B-protein_molecule O B-cell_type I-cell_type I-cell_type O O O O O O B-protein_family_or_group I-protein_family_or_group O B-protein_molecule I-protein_molecule I-protein_molecule I-protein_molecule I-protein_molecule I-protein_molecule I-protein_molecule O B-protein_molecule I-protein_molecule I-protein_molecule I-protein_molecule I-protein_molecule I-protein_molecule I-protein_molecule I-protein_molecule I-protein_molecule O O O O O O O O B-protein_family_or_group I-protein_family_or_group I-protein_family_or_group O