Since both AP-1 and NF-kappa B have been reported to be important in the induction of the tumor necrosis factor-alpha ( TNF-alpha ) gene we examined the effects of okadaic acid on TNF-alpha mRNA levels .
since both ap-1 and nf-kappa b have been reported to be important in the induction of the tumor necrosis factor-alpha ( tnf-alpha ) gene we examined the effects of okadaic acid on tnf-alpha mrna levels .
O O B-protein_molecule O B-protein_molecule I-protein_molecule O O O O O O O O O O O B-protein_molecule I-protein_molecule I-protein_molecule O O O O O O O O O B-other_organic_compound I-other_organic_compound O B-RNA_molecule I-RNA_molecule O O