Our data are most consistent with a model in which recruitment to the TCR allows ZAP-70 autophosphorylation and binding to p56 ( lck ) , which in turn phosphorylates Tyr-492 and/or Tyr-493 with consequent up-regulation of the ZAP-70 kinase activity .
our data are most consistent with a model in which recruitment to the tcr allows zap-70 autophosphorylation and binding to p56 ( lck ) , which in turn phosphorylates tyr-492 and/or tyr-493 with consequent up-regulation of the zap-70 kinase activity .
O O O O O O O O O O O O O B-protein_family_or_group O B-protein_molecule O O O O B-protein_molecule I-protein_molecule I-protein_molecule I-protein_molecule O O O O O B-amino_acid_monomer O B-amino_acid_monomer O O O O O B-protein_molecule O O O