We propose that the activation of an NFAT kinase by PDTC could be responsible for the rapid shuttling of the NFAT , therefore transiently converting the sustained transactivation of this transcription factor that occurs during lymphocyte activation , and show that c-Jun NH2-terminal kinase ( JNK ) can act by directly phosphorylating NFATp .
we propose that the activation of an nfat kinase by pdtc could be responsible for the rapid shuttling of the nfat , therefore transiently converting the sustained transactivation of this transcription factor that occurs during lymphocyte activation , and show that c-jun nh2-terminal kinase ( jnk ) can act by directly phosphorylating nfatp .
O O O O O O O O O O B-other_organic_compound O O O O O O O O O B-protein_family_or_group O O O O O O O O O B-protein_family_or_group I-protein_family_or_group O O O B-other_name I-other_name O O O O B-protein_molecule I-protein_molecule I-protein_molecule O B-protein_molecule O O O O O O B-protein_family_or_group O