We observed that FK506 suppressed the transcription of a chemotactic cytokine , interleukin-8 ( IL-8 ) in a human T cell line , Jurkat cells , activated by phorbol 12-myristate 13-acetate ( PMA ) and calcium ( Ca2+ ) ionophore ( ionomycin ) .
we observed that fk506 suppressed the transcription of a chemotactic cytokine , interleukin-8 ( il-8 ) in a human t cell line , jurkat cells , activated by phorbol 12-myristate 13-acetate ( pma ) and calcium ( ca2+ ) ionophore ( ionomycin ) .
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