NF-kappa B -directed luciferase activity increased approximately 3-fold when cells transfected with the plasmid pNF-kappa BLUC containing five copies of consensus NF-kappa B site linked to a minimal adenovirus E1B promoter-luciferase gene were exposed to thrombin , indicating that activation of NF-kappa B was essential for thrombin response .
nf-kappa b -directed luciferase activity increased approximately 3-fold when cells transfected with the plasmid pnf-kappa bluc containing five copies of consensus nf-kappa b site linked to a minimal adenovirus e1b promoter-luciferase gene were exposed to thrombin , indicating that activation of nf-kappa b was essential for thrombin response .
B-protein_molecule I-protein_molecule O B-protein_molecule O O O O O O O O O B-DNA_molecule I-DNA_molecule I-DNA_molecule O O O O B-DNA_domain_or_region B-protein_complex I-protein_complex O O O O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O O O B-protein_molecule O O O O O B-protein_complex I-protein_complex O O O B-protein_molecule O O