From these observations we conclude that free thiols in the IL-1RI complex are essential for the activation of the IL-1RI -associated protein kinase and that this process is mandatory for IL-1 signaling leading to NF-kappa B activation .
from these observations we conclude that free thiols in the il-1ri complex are essential for the activation of the il-1ri -associated protein kinase and that this process is mandatory for il-1 signaling leading to nf-kappa b activation .
O O O O O O O O O O B-protein_molecule O O O O O O O O B-protein_molecule O O O O O O O O O O B-protein_molecule O O O B-protein_complex I-protein_complex O O