The latter class of events is blocked in lymphocytes by the immunosuppressive drugs cyclosporin A and FK506 , which inhibit calcineurin , a Ca2+ -activated serine/threonine phosphatase necessary for the nuclear import of NF-AT transcription factors .
the latter class of events is blocked in lymphocytes by the immunosuppressive drugs cyclosporin a and fk506 , which inhibit calcineurin , a ca2+ -activated serine/threonine phosphatase necessary for the nuclear import of nf-at transcription factors .
O O O O O O O O B-cell_type O O B-other_organic_compound I-other_organic_compound B-other_organic_compound I-other_organic_compound O B-other_organic_compound O O O B-protein_molecule O O B-atom O O O O O O O O O B-protein_family_or_group B-protein_family_or_group I-protein_family_or_group O