Analysis of phosphotyrosine -containing proteins bound to truncated p85 constructs revealed cooperative binding of the two SH2 domains but no apparent differences between the N- and C- terminal SH2 domains .
analysis of phosphotyrosine -containing proteins bound to truncated p85 constructs revealed cooperative binding of the two sh2 domains but no apparent differences between the n- and c- terminal sh2 domains .
O O B-amino_acid_monomer O O O O O B-protein_subunit O O O O O O B-protein_domain_or_region I-protein_domain_or_region I-protein_domain_or_region O O O O O O O O O O O O O