Interleukin-2 ( IL-2 ) promoter activity stimulated by cross-linking of CD2 , TCR /CD3 , and CD28 with antibodies was significantly reduced by transient expression of an Itk mutant lacking the kinase activity .
interleukin-2 ( il-2 ) promoter activity stimulated by cross-linking of cd2 , tcr /cd3 , and cd28 with antibodies was significantly reduced by transient expression of an itk mutant lacking the kinase activity .
O O B-protein_molecule O O O O O O O B-protein_molecule O B-protein_family_or_group O O O B-protein_molecule O B-protein_family_or_group O O O O B-other_name I-other_name O O B-protein_molecule O O O B-other_name I-other_name O