To investigate the mechanisms responsible for tissue-specific expression of the IL-4 gene , we analyzed nuclear factors binding to the PRE-I site and compared the binding activities of these factors to the IL-4 promoter of Th1 and Th2 cells .
to investigate the mechanisms responsible for tissue-specific expression of the il-4 gene , we analyzed nuclear factors binding to the pre-i site and compared the binding activities of these factors to the il-4 promoter of th1 and th2 cells .
O O O O O O B-other_name I-other_name O O B-protein_molecule O O O O B-protein_family_or_group I-protein_family_or_group O O O B-DNA_domain_or_region I-DNA_domain_or_region O O O O O O O O O O B-protein_molecule O O O O O O O