We have previously demonstrated that a mutated form of the human CIITA gene , coding for a protein lacking the amino terminal 151 amino acids , acts as a potent dominant-negative suppressor of HLA class II expression .
we have previously demonstrated that a mutated form of the human ciita gene , coding for a protein lacking the amino terminal 151 amino acids , acts as a potent dominant-negative suppressor of hla class ii expression .
O O O O O O O O O O B-DNA_domain_or_region B-protein_molecule O O O O O O O O B-protein_domain_or_region I-protein_domain_or_region I-protein_domain_or_region I-protein_domain_or_region I-protein_domain_or_region O O O O O B-other_name I-other_name O B-protein_family_or_group I-protein_family_or_group I-protein_family_or_group O O