Importantly , jagged1 transcripts were also upregulated by endogenous NF-kappaB activation and this effect was inhibited by a dominant mutant of IkappaBalpha , a physiological inhibitor of NF-kappaB .
importantly , jagged1 transcripts were also upregulated by endogenous nf-kappab activation and this effect was inhibited by a dominant mutant of ikappabalpha , a physiological inhibitor of nf-kappab .
O O B-protein_family_or_group I-protein_family_or_group O O O O O B-protein_complex O O O O O O O O O O O B-protein_molecule O O O O O B-protein_complex O