Therefore , IL-10 can directly inhibit STAT-dependent early response gene expression induced by both IFNalpha and IFNgamma in monocytes by suppressing the tyrosine phosphorylation of STAT1 .
therefore , il-10 can directly inhibit stat-dependent early response gene expression induced by both ifnalpha and ifngamma in monocytes by suppressing the tyrosine phosphorylation of stat1 .
O O B-protein_molecule O O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O O O O B-protein_molecule O B-protein_molecule O B-cell_type O O O B-amino_acid_monomer O O B-protein_molecule O