The minimal region of the human tumor necrosis factor alpha ( TNF-alpha ) gene promoter necessary for its transcriptional induction by phorbol esters ( PMA ) in human T and B lymphocyte cell lines has been localized between -52 and +89 nucleotides ( nt ) relative to the gene's transcriptional start site .
the minimal region of the human tumor necrosis factor alpha ( tnf-alpha ) gene promoter necessary for its transcriptional induction by phorbol esters ( pma ) in human t and b lymphocyte cell lines has been localized between -52 and +89 nucleotides ( nt ) relative to the gene's transcriptional start site .
O O O O O B-protein_molecule I-protein_molecule I-protein_molecule I-protein_molecule I-protein_molecule O B-protein_molecule O O O O O O O O O B-other_organic_compound I-other_organic_compound O B-other_organic_compound O O B-cell_line I-cell_line O B-cell_line I-cell_line I-cell_line I-cell_line O O O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O O O O O O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O