By contrast , three lymphoblastoid cell lines ( immortalized in vitro with Epstein-Barr virus ) were weakly positive and MNDA was up-regulated by interferon-alpha ( IFN-alpha ) treatment .
by contrast , three lymphoblastoid cell lines ( immortalized in vitro with epstein-barr virus ) were weakly positive and mnda was up-regulated by interferon-alpha ( ifn-alpha ) treatment .
O O O O B-cell_line I-cell_line I-cell_line O O O O O B-virus I-virus O O O O O B-protein_molecule O O O B-protein_molecule O B-protein_molecule O O O