Alanine substitutions introduced at two serine residues positioned within this N-terminal regulatory region of I kappa B alpha also yielded constitutive repressors that escaped from Tax -induced turnover and that potently inhibited immune activation pathways for NF-kappa B induction , including those initiated from antigen and cytokine receptors .
alanine substitutions introduced at two serine residues positioned within this n-terminal regulatory region of i kappa b alpha also yielded constitutive repressors that escaped from tax -induced turnover and that potently inhibited immune activation pathways for nf-kappa b induction , including those initiated from antigen and cytokine receptors .
O O O O O B-amino_acid_monomer I-amino_acid_monomer O O O B-protein_domain_or_region I-protein_domain_or_region I-protein_domain_or_region O B-protein_molecule I-protein_molecule I-protein_molecule I-protein_molecule O O O O O O O B-protein_molecule O O O O O O B-other_name I-other_name I-other_name O B-protein_molecule I-protein_molecule O O O O O O O O O O O