CD40 signaling activates downstream effectors , including the tyrosine protein kinase , Lyn , the phosphatidylinositol-3-kinase ( PI-3 kinase ) , and the transcription factor , NF-kappa B .
cd40 signaling activates downstream effectors , including the tyrosine protein kinase , lyn , the phosphatidylinositol-3-kinase ( pi-3 kinase ) , and the transcription factor , nf-kappa b .
B-protein_molecule O O B-protein_family_or_group I-protein_family_or_group O O O B-protein_family_or_group I-protein_family_or_group I-protein_family_or_group O B-protein_molecule O O B-protein_molecule O B-protein_molecule I-protein_molecule O O O O O O O B-protein_complex I-protein_complex O