We have shown elsewhere that both the major immediate-early gene ( MIE ) and lytic cycle infectious progeny virus expression can be induced in otherwise nonpermissive monocyte-like U-937 cell cultures infected with either human CMV ( HCMV ) or simian CMV ( SCMV ) by treatment with the phorbol ester 12-O-tetradecanoylphorbol-13-acetate ( TPA ) .
we have shown elsewhere that both the major immediate-early gene ( mie ) and lytic cycle infectious progeny virus expression can be induced in otherwise nonpermissive monocyte-like u-937 cell cultures infected with either human cmv ( hcmv ) or simian cmv ( scmv ) by treatment with the phorbol ester 12-o-tetradecanoylphorbol-13-acetate ( tpa ) .
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