Thus , gammac is not necessary to trigger IL-4 -mediated responses in B cells , but its presence is important for optimal IL-4 -signaling .
thus , gammac is not necessary to trigger il-4 -mediated responses in b cells , but its presence is important for optimal il-4 -signaling .
O O B-protein_molecule O O O O O B-protein_molecule O O O B-cell_type I-cell_type O O O O O O O B-other_name B-protein_molecule O O