Furthermore , S9a and AZT in combination , at noncytoxic concentrations strongly inhibited HIV-1 replication that was more than additive and substantially prolonged the appearance of virus both in acutely infected CD4+ lymphocytes ( SupT ) in culture and in peripheral blood mononuclear cells ( PBMCs ) infected with a primary HIV-1 isolate .
furthermore , s9a and azt in combination , at noncytoxic concentrations strongly inhibited hiv-1 replication that was more than additive and substantially prolonged the appearance of virus both in acutely infected cd4+ lymphocytes ( supt ) in culture and in peripheral blood mononuclear cells ( pbmcs ) infected with a primary hiv-1 isolate .
O O O O B-other_organic_compound O O O O B-other_name I-other_name O O B-virus O O O O O O O O O O O O O O O B-cell_type I-cell_type I-cell_type I-cell_type O B-cell_line O O O O O B-cell_type I-cell_type I-cell_type I-cell_type O B-cell_type O O O O B-virus B-virus O O