An NH2-terminal truncation mutant of TRAF6 inhibited RANKL -mediated NF-kappaB activation , but failed to affect constitutive signaling induced by receptor overexpression , revealing a selective role for TRAF6 in ligand-induced activation events .
an nh2-terminal truncation mutant of traf6 inhibited rankl -mediated nf-kappab activation , but failed to affect constitutive signaling induced by receptor overexpression , revealing a selective role for traf6 in ligand-induced activation events .
O B-protein_molecule I-protein_molecule I-protein_molecule O B-protein_molecule O B-protein_molecule O B-protein_complex O O O O O O O O O O B-other_name I-other_name O O O O O O B-protein_molecule O B-other_name I-other_name I-other_name O