Deletion constructs containing as little as 72 bp of 5' -flanking sequence of the collagenase promoter were sufficient for LPS- or zymosan- mediated transcriptional induction , whereas phorbol inducibility exhibited an absolute requirement for upstream elements including the polyoma enhancer A-binding protein-3 site ( -83 to -91 ) and TTCA sequence ( -102 to -105 ) in both monocytic cells and fibroblasts .
deletion constructs containing as little as 72 bp of 5' -flanking sequence of the collagenase promoter were sufficient for lps- or zymosan- mediated transcriptional induction , whereas phorbol inducibility exhibited an absolute requirement for upstream elements including the polyoma enhancer a-binding protein-3 site ( -83 to -91 ) and ttca sequence ( -102 to -105 ) in both monocytic cells and fibroblasts .
O O O O O O B-polynucleotide I-polynucleotide O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O O B-protein_molecule O O O O O O O O O O O O B-other_organic_compound O O O O O O O O O O B-DNA_domain_or_region I-DNA_domain_or_region O O O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O O B-DNA_domain_or_region I-DNA_domain_or_region O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O O O B-cell_type I-cell_type O B-cell_type O