Cytokine and growth factor receptor engagement leads to the rapid phosphorylation and activation of latent , cytosolic signal transducers and activators of transcription ( STAT ) proteins , which then translocate to the nucleus where they regulate transcriptional events from specific promoter sequences .
cytokine and growth factor receptor engagement leads to the rapid phosphorylation and activation of latent , cytosolic signal transducers and activators of transcription ( stat ) proteins , which then translocate to the nucleus where they regulate transcriptional events from specific promoter sequences .
B-protein_family_or_group O B-protein_family_or_group I-protein_family_or_group I-protein_family_or_group O O O O B-other_name I-other_name O O O O O B-protein_family_or_group I-protein_family_or_group I-protein_family_or_group I-protein_family_or_group I-protein_family_or_group I-protein_family_or_group I-protein_family_or_group I-protein_family_or_group I-protein_family_or_group I-protein_family_or_group I-protein_family_or_group O O O O O O B-cell_component O O O O O O B-DNA_family_or_group I-DNA_family_or_group I-DNA_family_or_group O