The HSFE induced an area of enhanced DNase 1 hypersensitivity extending from the transcriptional start site to -300bp of the artificial promoter and significantly increased the proportion of beta-globin promoters in an open chromatin configuration .
the hsfe induced an area of enhanced dnase 1 hypersensitivity extending from the transcriptional start site to -300bp of the artificial promoter and significantly increased the proportion of beta-globin promoters in an open chromatin configuration .
O B-DNA_domain_or_region O O O O B-other_name B-protein_molecule I-protein_molecule O O O O O O O O O O O B-DNA_molecule I-DNA_molecule O O O O O O B-DNA_domain_or_region I-DNA_domain_or_region O O B-DNA_substructure I-DNA_substructure I-DNA_substructure O