The rearrangements lead either to gene truncation , and to expression of the transcription repressor EVI1 , as seen in the t ( 3 ; 3 ) ( q21 ; q26 ) and inv ( 3 ) ( q21q26 ) , or to gene fusion , as seen in the t ( 3 ; 21 ) ( q26 ; q22 ) which results in the fusion protein AML1/MDS1/EVI1 .
the rearrangements lead either to gene truncation , and to expression of the transcription repressor evi1 , as seen in the t ( 3 ; 3 ) ( q21 ; q26 ) and inv ( 3 ) ( q21q26 ) , or to gene fusion , as seen in the t ( 3 ; 21 ) ( q26 ; q22 ) which results in the fusion protein aml1/mds1/evi1 .
O O O O O O O O O O O O O B-protein_molecule I-protein_molecule I-protein_molecule O O O O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O O O B-other_name I-other_name O O O O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O O O O O O B-protein_molecule O