Further , M . tuberculosis and its tuberculin , purified protein derivative , induced the degradation of I kappa B-alpha and the expression of I kappa B-alpha mRNA , and purified protein derivative induced the activation of NF-kappa B in monocytes .
further , m . tuberculosis and its tuberculin , purified protein derivative , induced the degradation of i kappa b-alpha and the expression of i kappa b-alpha mrna , and purified protein derivative induced the activation of nf-kappa b in monocytes .
O O B-mono_cell I-mono_cell I-mono_cell O O B-protein_molecule O B-protein_family_or_group I-protein_family_or_group I-protein_family_or_group O O O O O B-protein_molecule I-protein_molecule I-protein_molecule O O O O B-protein_molecule I-protein_molecule I-protein_molecule O O O O O O O O O O B-protein_complex I-protein_complex O B-cell_type O