Pretreatment of cells with protein tyrosine kinase inhibitors and the dominant negative allele of c-Raf-1 ( Raf 301 ) inhibited I kappa B alpha degradation , NF-kappa B binding , and transactivation of kappa B reporter constructs by hypoxia .
pretreatment of cells with protein tyrosine kinase inhibitors and the dominant negative allele of c-raf-1 ( raf 301 ) inhibited i kappa b alpha degradation , nf-kappa b binding , and transactivation of kappa b reporter constructs by hypoxia .
O O O O B-other_organic_compound B-amino_acid_monomer O O O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O B-DNA_domain_or_region O B-protein_molecule I-protein_molecule O O B-protein_molecule I-protein_molecule I-protein_molecule I-protein_molecule O O B-protein_molecule I-protein_molecule O O O O O B-DNA_molecule I-DNA_molecule I-DNA_molecule I-DNA_molecule O B-other_name O