Since human immunodeficiency virus type 1 ( HIV-1 ) replication is known to be favored under oxidative stress conditions , ex vivo experiments using uninfected PBMCs , primary monocytes or a latently infected promonocytic U1 cell line show that HIV-1 replication and reactivation , monitored by p24 antigen measurement , are inhibited by PAO in a time- and concentration-dependent manner .
since human immunodeficiency virus type 1 ( hiv-1 ) replication is known to be favored under oxidative stress conditions , ex vivo experiments using uninfected pbmcs , primary monocytes or a latently infected promonocytic u1 cell line show that hiv-1 replication and reactivation , monitored by p24 antigen measurement , are inhibited by pao in a time- and concentration-dependent manner .
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