In addition , JNK activation by PMA plus ionophore was sensitive to inhibitors of signaling pathways involving Ca2+ , protein kinase C , and tyrosine phosphorylation , which failed to inhibit the activation mediated by PDTC .
in addition , jnk activation by pma plus ionophore was sensitive to inhibitors of signaling pathways involving ca2+ , protein kinase c , and tyrosine phosphorylation , which failed to inhibit the activation mediated by pdtc .
O O O B-protein_molecule O O B-other_organic_compound O O O O O O O O O O B-atom O B-protein_molecule I-protein_molecule I-protein_molecule O O O O O O O O O O O O O B-other_organic_compound O