Second , in contrast to recent results on human cell lines , CIITA is not critically involved in the IFN-gamma -induced up-regulation of MHC class I genes .
second , in contrast to recent results on human cell lines , ciita is not critically involved in the ifn-gamma -induced up-regulation of mhc class i genes .
O O O O O O O O B-cell_line I-cell_line I-cell_line O B-protein_molecule O O O O O O B-protein_molecule O O O B-DNA_family_or_group I-DNA_family_or_group I-DNA_family_or_group I-DNA_family_or_group O