Binding of type I interferon ( IFN-alpha/beta ) to specific receptors results in the rapid transcriptional activation , independent of protein synthesis , of IFN-alpha-stimulated genes ( ISGs ) in human fibroblasts and HeLa and Daudi cell lines .
binding of type i interferon ( ifn-alpha/beta ) to specific receptors results in the rapid transcriptional activation , independent of protein synthesis , of ifn-alpha-stimulated genes ( isgs ) in human fibroblasts and hela and daudi cell lines .
O O B-protein_family_or_group I-protein_family_or_group I-protein_family_or_group I-protein_family_or_group B-protein_molecule O O O O O O O B-other_name I-other_name I-other_name O O O B-other_name I-other_name O O B-DNA_family_or_group I-DNA_family_or_group O B-DNA_family_or_group O O B-cell_type I-cell_type O B-cell_line O B-cell_line I-cell_line I-cell_line O