We found that the spontaneous production of tumor necrosis factor alpha and other pro-inflammatory cytokines is NF-kappaB -dependent in rheumatoid synovial tissue , in contrast to the main anti-inflammatory mediators , like IL -10 and -11 , and the IL-1 receptor antagonist .
we found that the spontaneous production of tumor necrosis factor alpha and other pro-inflammatory cytokines is nf-kappab -dependent in rheumatoid synovial tissue , in contrast to the main anti-inflammatory mediators , like il -10 and -11 , and the il-1 receptor antagonist .
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