Previous reports have suggested the CD28 stimulation contributes to the activation of the IL-2 promoter by up-regulating the activity of several transcription factors , including AP-1 and nuclear factor-kappaB ( NF-kappaB ) / Rel family members as well as an uncharacterized transcription factor called CD28 response complex .
previous reports have suggested the cd28 stimulation contributes to the activation of the il-2 promoter by up-regulating the activity of several transcription factors , including ap-1 and nuclear factor-kappab ( nf-kappab ) / rel family members as well as an uncharacterized transcription factor called cd28 response complex .
O O O O O B-protein_molecule O O O O O O O B-protein_molecule O O O O O O O B-protein_family_or_group I-protein_family_or_group O O B-protein_molecule O B-protein_complex I-protein_complex O B-protein_complex O O B-protein_family_or_group O O O O O O B-protein_family_or_group I-protein_family_or_group I-protein_family_or_group O B-protein_molecule O O O