Azeptin dose-dependently suppressed both DNA and protein synthesis in human gingival fibroblasts ( HF ) and also suppressed blastogenesis of human peripheral blood lymphocytes ( PBL ) . Generation of tumor necrosis factor-alpha , interleukin 1-beta , granulocyte-macrophage colony-stimulating factor and interleukin-6 from 10 ( -5 ) M Azeptin -treated PBL and human monocytes ( HM ) was decreased to approximately 1/3 to 2/3 of the control levels .
azeptin dose-dependently suppressed both dna and protein synthesis in human gingival fibroblasts ( hf ) and also suppressed blastogenesis of human peripheral blood lymphocytes ( pbl ) . generation of tumor necrosis factor-alpha , interleukin 1-beta , granulocyte-macrophage colony-stimulating factor and interleukin-6 from 10 ( -5 ) m azeptin -treated pbl and human monocytes ( hm ) was decreased to approximately 1/3 to 2/3 of the control levels .
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