Costimulation of T cells through both the Ag receptor and CD28 leads to high level IL-2 production , which is vital to the development of an immune response in vivo .
costimulation of t cells through both the ag receptor and cd28 leads to high level il-2 production , which is vital to the development of an immune response in vivo .
O O B-cell_type I-cell_type O O O O O O B-protein_molecule O O O O B-protein_molecule O O O O O O O O O O O O O O O