Four patients ( 22% ) had a family history of breast/ovarian cancer in at least one first- or second-degree relative ; however , no BRCA2 mutation was identified among them .
four patients ( 22% ) had a family history of breast/ovarian cancer in at least one first- or second-degree relative ; however , no brca2 mutation was identified among them .
O B-multi_cell O O O O O O O O B-other_name I-other_name O O O O O O O O O O O O B-DNA_domain_or_region O O O O O O