Thus , tyrosine phosphorylation is an important and perhaps mandatory proximal step in the activation of the protein kinase C signaling cascade in human B-lymphocyte precursors .
thus , tyrosine phosphorylation is an important and perhaps mandatory proximal step in the activation of the protein kinase c signaling cascade in human b-lymphocyte precursors .
O O B-amino_acid_monomer O O O O O O O O O O O O O O B-protein_family_or_group I-protein_family_or_group I-protein_family_or_group O O O B-cell_type I-cell_type I-cell_type O