Transactivation by recombinant NFAT1 in Jurkat T cells requires dual stimulation with ionomycin and phorbol 12-myristate 13-acetate ; this activity is potentiated by coexpression of constitutively active calcineurin and is inhibited by CsA .
transactivation by recombinant nfat1 in jurkat t cells requires dual stimulation with ionomycin and phorbol 12-myristate 13-acetate ; this activity is potentiated by coexpression of constitutively active calcineurin and is inhibited by csa .
O O O B-protein_molecule O B-cell_line I-cell_line I-cell_line O O O O B-other_organic_compound O B-other_organic_compound I-other_organic_compound I-other_organic_compound O O O O O O O O O O B-protein_molecule O O O O B-other_organic_compound O