Previously we and others showed by targeted gene disruption that the zinc finger gene , erythroid Kruppel-like factor ( EKLF ) , is required for expression of the beta-globin gene in mice , presumably through interaction with a high-affinity binding site in the proximal promoter .
previously we and others showed by targeted gene disruption that the zinc finger gene , erythroid kruppel-like factor ( eklf ) , is required for expression of the beta-globin gene in mice , presumably through interaction with a high-affinity binding site in the proximal promoter .
O O O O O O O B-other_name I-other_name O O B-DNA_family_or_group I-DNA_family_or_group I-DNA_family_or_group O B-protein_molecule I-protein_molecule I-protein_molecule O B-protein_molecule O O O O O O O O B-DNA_family_or_group I-DNA_family_or_group O B-multi_cell O O O O O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O O B-DNA_domain_or_region I-DNA_domain_or_region O