By using deletion mutants of the c-fos promoter , we found that the minimal DNA sequence required for Tat activity was located between nucleotides -404/-220 and that the serum responsive element ( SRE , -317/-288 ) , present within this region , was still responsive to Tat .
by using deletion mutants of the c-fos promoter , we found that the minimal dna sequence required for tat activity was located between nucleotides -404/-220 and that the serum responsive element ( sre , -317/-288 ) , present within this region , was still responsive to tat .
O O O O O O B-DNA_domain_or_region I-DNA_domain_or_region O O O O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O O B-protein_molecule O O O O B-DNA_domain_or_region I-DNA_domain_or_region O O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O B-DNA_domain_or_region O B-DNA_domain_or_region O O O O O O O O O O O B-protein_molecule O