Although the mechanism of LTR activation remains obscure , several lines of investigation have suggested that it is a result of activation of the NF-kappa B transcription factor ( s ) following signaling events related to generalized DNA damage .
although the mechanism of ltr activation remains obscure , several lines of investigation have suggested that it is a result of activation of the nf-kappa b transcription factor ( s ) following signaling events related to generalized dna damage .
O O O O B-DNA_domain_or_region O O O O O O O O O O O O O O O O O O O B-protein_complex I-protein_complex B-protein_family_or_group I-protein_family_or_group O O O O O O O O B-other_name I-other_name I-other_name O