In contrast to wild-type B cells , neither of the class II mutant cell lines could use the X box region to direct the expression of a transiently transfected reporter gene , indicating that the X box-dependent transcriptional pathway is defective in these cells .
in contrast to wild-type b cells , neither of the class ii mutant cell lines could use the x box region to direct the expression of a transiently transfected reporter gene , indicating that the x box-dependent transcriptional pathway is defective in these cells .
O O O B-cell_line I-cell_line I-cell_line O O O O B-cell_line I-cell_line I-cell_line I-cell_line I-cell_line O O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O O O O O O O O B-DNA_family_or_group I-DNA_family_or_group O O O O B-other_name I-other_name I-other_name I-other_name O O O O O O