When the wild-type hGR and hGR -Ile 729 were expressed in CV-1 cells that were cotransfected with the mouse mammary tumor virus long terminal repeat fused to the chloramphenicol acetyl transferase ( CAT ) gene , the hGR -Ile 729 conferred a fourfold decrease in apparent potency on dexamethasone stimulation of CAT activity .
when the wild-type hgr and hgr -ile 729 were expressed in cv-1 cells that were cotransfected with the mouse mammary tumor virus long terminal repeat fused to the chloramphenicol acetyl transferase ( cat ) gene , the hgr -ile 729 conferred a fourfold decrease in apparent potency on dexamethasone stimulation of cat activity .
O O B-protein_molecule B-protein_family_or_group O B-protein_family_or_group O O O O O B-cell_line I-cell_line O O O O O B-virus I-virus I-virus I-virus O O O O O O B-protein_molecule I-protein_molecule I-protein_molecule O B-protein_molecule O O O O B-protein_family_or_group O O O O O O O O O O B-lipid O O B-protein_molecule O O