The transcription factor E2F activates the expression of multiple genes involved in cell proliferation , such as c-myc and the dihydrofolate reductase gene .
the transcription factor e2f activates the expression of multiple genes involved in cell proliferation , such as c-myc and the dihydrofolate reductase gene .
O B-protein_family_or_group I-protein_family_or_group B-protein_molecule O O O O O B-DNA_family_or_group O O B-other_name I-other_name O O O B-DNA_domain_or_region O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O