This mutant also functions in vivo as a trans-acting dominant negative regulator : the transcriptional inducibility of the HIV long terminal repeat ( which contains two potential NF-kappa B binding sites ) by phorbol ester ( PMA ) is inhibited when it is co-transfected into CD4+ T cells with the delta SP mutant .
this mutant also functions in vivo as a trans-acting dominant negative regulator : the transcriptional inducibility of the hiv long terminal repeat ( which contains two potential nf-kappa b binding sites ) by phorbol ester ( pma ) is inhibited when it is co-transfected into cd4+ t cells with the delta sp mutant .
O O O O O O O O B-protein_family_or_group I-protein_family_or_group I-protein_family_or_group I-protein_family_or_group O O B-other_name I-other_name O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O O O O O B-protein_molecule I-protein_molecule O O O O B-other_organic_compound I-other_organic_compound O B-other_organic_compound O O O O O O O O B-cell_line I-cell_line I-cell_line O O B-protein_molecule I-protein_molecule O O