In this report , we show that exposure of cells to hypoxia ( 0 . 02% O2 ) results in I kappa B alpha degradation , increased NF-kappa B DNA binding activity , and transactivation of a reporter gene construct containing two NF-kappa B DNA binding sites .
in this report , we show that exposure of cells to hypoxia ( 0 . 02% o2 ) results in i kappa b alpha degradation , increased nf-kappa b dna binding activity , and transactivation of a reporter gene construct containing two nf-kappa b dna binding sites .
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