These data suggest the potential utility of agents that disrupt calcineurin -mediated signal transduction pathways by blocking formation of the catalytically active dimer of calcineurin A and B subunits .
these data suggest the potential utility of agents that disrupt calcineurin -mediated signal transduction pathways by blocking formation of the catalytically active dimer of calcineurin a and b subunits .
O O O O O O O O O O B-protein_molecule O O O O O O O O O B-protein_complex I-protein_complex I-protein_complex O O O O O O O