In previous studies , we identified calcineurin mutations that block binding by the cyclophilin A /CsA or FKBP12 /FK506 complexes and thereby render yeast cells resistant to the antifungal effects of CsA or FK506 .
in previous studies , we identified calcineurin mutations that block binding by the cyclophilin a /csa or fkbp12 /fk506 complexes and thereby render yeast cells resistant to the antifungal effects of csa or fk506 .
O O O O O O B-protein_molecule O O O O O O B-protein_molecule I-protein_molecule B-other_organic_compound O B-protein_molecule B-other_organic_compound O O O O B-mono_cell I-mono_cell O O O B-other_name I-other_name O B-other_organic_compound O B-other_organic_compound O