Using transfection and reporter gene assays specifically designed for primary T lymphocytes in conjunction with gel retardation assays , Western blot analyses and UV cross-linking studies , we found that c-Jun , c-Fos , and octamer-binding proteins play a major role in transcriptional activation of the IL3 gene via their interaction with two specific regions contained within the IL3 5'-flanking sequence .
using transfection and reporter gene assays specifically designed for primary t lymphocytes in conjunction with gel retardation assays , western blot analyses and uv cross-linking studies , we found that c-jun , c-fos , and octamer-binding proteins play a major role in transcriptional activation of the il3 gene via their interaction with two specific regions contained within the il3 5'-flanking sequence .
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