Data is presented , using the potent and selective PKC inhibitor Ro 31-8425 and transient expression of a constitutively active ras mutant , which clearly shows that PKC is not downstream of p21ras in the induction of NF-AT and AP-1 transcriptional activity and in the expression of IL-2 in human Jurkat T cells .
data is presented , using the potent and selective pkc inhibitor ro 31-8425 and transient expression of a constitutively active ras mutant , which clearly shows that pkc is not downstream of p21ras in the induction of nf-at and ap-1 transcriptional activity and in the expression of il-2 in human jurkat t cells .
O O O O O O O O O B-protein_molecule O B-other_organic_compound I-other_organic_compound O O O O O O O O O O O O O O B-protein_molecule O O O O B-DNA_domain_or_region O O O O B-protein_molecule O B-protein_molecule O O O O O O O B-protein_molecule O B-cell_line I-cell_line I-cell_line I-cell_line O