Heterokaryons formed by the fusion of anergic murine T cells to normal murine T cells also failed to accumulate intracellular IL-2 protein in response to stimulation either with the combination of CD3 and CD28 mAbs or with ionomycin plus a protein kinase C -activating phorbol ester .
heterokaryons formed by the fusion of anergic murine t cells to normal murine t cells also failed to accumulate intracellular il-2 protein in response to stimulation either with the combination of cd3 and cd28 mabs or with ionomycin plus a protein kinase c -activating phorbol ester .
B-cell_line O O O O O B-cell_type I-cell_type I-cell_type I-cell_type O B-cell_type I-cell_type I-cell_type I-cell_type O O O O B-protein_molecule I-protein_molecule I-protein_molecule O O O O O O O O O B-protein_family_or_group O B-protein_family_or_group I-protein_family_or_group O O B-other_organic_compound O O B-protein_molecule I-protein_molecule I-protein_molecule O O O O