In previous studies , it was shown that the fusion region of the pml/RAR-alpha protein , expressed by acute promyelocytic leukemia ( APL ) cells , can be specifically recognized in vitro by donor ( D . E . ) CD4 T cells in a HLA class II DR11-restricted fashion .
in previous studies , it was shown that the fusion region of the pml/rar-alpha protein , expressed by acute promyelocytic leukemia ( apl ) cells , can be specifically recognized in vitro by donor ( d . e . ) cd4 t cells in a hla class ii dr11-restricted fashion .
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