Furthermore , a truncated form of NFAT1 acts as a dominant-negative , reducing IL-4 promoter activity in primed CD4 T cells and confirming the importance of endogenous NFAT to increased IL-4 gene expression by effector T cells .
furthermore , a truncated form of nfat1 acts as a dominant-negative , reducing il-4 promoter activity in primed cd4 t cells and confirming the importance of endogenous nfat to increased il-4 gene expression by effector t cells .
O O O O O O B-protein_molecule O O O O O O B-protein_molecule O O O O B-cell_type I-cell_type I-cell_type O O O O O B-protein_family_or_group I-protein_family_or_group O O B-protein_molecule O O O O O O O