However , for the clonal expansion of CD4+ T-cells , which is a characteristic result of HTLV-I infection , activation of the CREB/ATF and SRF pathways is also required .
however , for the clonal expansion of cd4+ t-cells , which is a characteristic result of htlv-i infection , activation of the creb/atf and srf pathways is also required .
O O O O O O O B-cell_type I-cell_type O O O O O O O B-virus O O O O O O O O O O O O O