We demonstrate here that the expression of the lysosomal enzyme acid sphingomyelinase ( ASM ; E . C . 3 . 1 . 4 . 12 ) is induced during this process and is strongly elevated in differentiated THP-1 cells , as well as in differentiated human mononuclear phagocytes .
we demonstrate here that the expression of the lysosomal enzyme acid sphingomyelinase ( asm ; e . c . 3 . 1 . 4 . 12 ) is induced during this process and is strongly elevated in differentiated thp-1 cells , as well as in differentiated human mononuclear phagocytes .
O O O O O O O O B-protein_family_or_group I-protein_family_or_group B-protein_family_or_group I-protein_family_or_group O O O O O O O O O O O O O O O O O O O O O O O O O O B-cell_line I-cell_line O O O O O O B-cell_type I-cell_type I-cell_type O