While IL-4 does not activate STAT5 , it induces expression of STAT5 -regulated genes in CTLL-2 , i . e . beta-casein , a cytokine-inducible SH2-containing protein ( CIS ) , and oncostatin M ( OSM ) , suggesting that STAT6 activated by IL-4 substitutes for the function of STAT5 in T cells .
while il-4 does not activate stat5 , it induces expression of stat5 -regulated genes in ctll-2 , i . e . beta-casein , a cytokine-inducible sh2-containing protein ( cis ) , and oncostatin m ( osm ) , suggesting that stat6 activated by il-4 substitutes for the function of stat5 in t cells .
O B-protein_molecule O O O B-protein_molecule O O O O O B-protein_molecule O O O B-cell_line O O O O O B-protein_molecule O O B-protein_family_or_group I-protein_family_or_group I-protein_family_or_group O B-protein_molecule O O O B-protein_molecule I-protein_molecule O B-protein_molecule O O O O O O O B-protein_molecule O O O O O B-protein_molecule O B-cell_type I-cell_type O