CD45 -dependent events such as tyrosine phosphorylation of Shc , activation of nuclear factor-kappa B ( NF-kappa B ) , activator protein-1 ( AP-1 ) , transcription factors , and stimulation of interleukin-2 ( IL-2 ) promoter and of CD69 and CD25 surface expression paralleled activation of the tyrosine kinases lck and fyn .
cd45 -dependent events such as tyrosine phosphorylation of shc , activation of nuclear factor-kappa b ( nf-kappa b ) , activator protein-1 ( ap-1 ) , transcription factors , and stimulation of interleukin-2 ( il-2 ) promoter and of cd69 and cd25 surface expression paralleled activation of the tyrosine kinases lck and fyn .
B-protein_molecule O O O O B-protein_molecule I-protein_molecule O B-protein_molecule O O O B-protein_complex I-protein_complex I-protein_complex O B-protein_complex I-protein_complex O O B-protein_molecule I-protein_molecule O B-protein_molecule O O B-protein_family_or_group I-protein_family_or_group O O O O B-protein_molecule O B-protein_molecule O O O O B-protein_molecule O B-protein_molecule B-other_name I-other_name O O O O B-protein_family_or_group I-protein_family_or_group B-protein_molecule O B-protein_molecule O