Since kappa B motifs are present in VCAM-1 and intercellular adhesion molecule-1 ( ICAM-1 ) promoters , we used PDTC to study the regulatory mechanisms of VCAM-1 and ICAM-1 induction and subsequent monocyte adhesion in TNF-treated human umbilical vein endothelial cells ( HUVECs ) .
since kappa b motifs are present in vcam-1 and intercellular adhesion molecule-1 ( icam-1 ) promoters , we used pdtc to study the regulatory mechanisms of vcam-1 and icam-1 induction and subsequent monocyte adhesion in tnf-treated human umbilical vein endothelial cells ( huvecs ) .
O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O O O B-DNA_domain_or_region O B-protein_molecule I-protein_molecule I-protein_molecule O B-protein_molecule O O O O O B-other_organic_compound O O O O O O B-protein_molecule O B-protein_molecule O O O B-cell_type O O B-cell_line I-cell_line I-cell_line I-cell_line B-cell_type I-cell_type O B-cell_line O O