In contrast , mutagenesis of proximal NF-kappa B motif ( L1 ) had minimal effects on gene expression in both HeLa cells and lymphoid cells but resulted in a small , but reproducible , increase in gene expression in lymphoid cells when coupled to the L2 mutation .
in contrast , mutagenesis of proximal nf-kappa b motif ( l1 ) had minimal effects on gene expression in both hela cells and lymphoid cells but resulted in a small , but reproducible , increase in gene expression in lymphoid cells when coupled to the l2 mutation .
O O O O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O B-DNA_domain_or_region O O O O O B-other_name B-other_name O O B-cell_line I-cell_line O B-cell_type I-cell_type O O O O O O O O O O O B-other_name B-other_name O B-cell_type I-cell_type O O O O B-DNA_domain_or_region O O