In the present study , we showed that CD14+ adherent human monocytes can differentiate into CD1+relB+ dendritic cells ( DC ) by the combination of GM-CSF plus interleukin-4 ( IL-4 ) and that they differentiate into tartrate-resistant acid phosphatase ( TRAP ) -positive osteoclast-like multinucleated giant cells ( MGC ) by the combination of M-CSF plus IL-4 .
in the present study , we showed that cd14+ adherent human monocytes can differentiate into cd1+relb+ dendritic cells ( dc ) by the combination of gm-csf plus interleukin-4 ( il-4 ) and that they differentiate into tartrate-resistant acid phosphatase ( trap ) -positive osteoclast-like multinucleated giant cells ( mgc ) by the combination of m-csf plus il-4 .
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