We show here that IFN-alpha/beta act directly on human T cells to drive Th1 development , bypassing the need for IL-12 -induced signaling , whereas IFN-alpha cannot substitute IL-12 for mouse Th1 development .
we show here that ifn-alpha/beta act directly on human t cells to drive th1 development , bypassing the need for il-12 -induced signaling , whereas ifn-alpha cannot substitute il-12 for mouse th1 development .
O O O O B-protein_molecule O O O B-cell_type I-cell_type I-cell_type O O B-other_name I-other_name O O O O O B-protein_molecule O O O O B-protein_molecule O O B-protein_molecule O O B-other_name I-other_name O