Human IL-5 promoter/enhancer-luciferase gene construct transfected to T-cell clones was transcribed on either TCR or IL-2R stimulation and was clearly downregulated by dexamethasone , indicating that the approximately 500-bp human IL-5 gene segment located 5' upstream of the coding region contains activation-inducible enhancer elements responsible for the regulation by GC .
human il-5 promoter/enhancer-luciferase gene construct transfected to t-cell clones was transcribed on either tcr or il-2r stimulation and was clearly downregulated by dexamethasone , indicating that the approximately 500-bp human il-5 gene segment located 5' upstream of the coding region contains activation-inducible enhancer elements responsible for the regulation by gc .
O B-protein_molecule O O O O O B-cell_line I-cell_line O O O O B-protein_family_or_group O B-protein_molecule O O O O O O B-lipid O O O O O B-DNA_domain_or_region I-DNA_domain_or_region B-protein_molecule O O O B-DNA_domain_or_region I-DNA_domain_or_region O O O O O B-DNA_family_or_group I-DNA_family_or_group I-DNA_family_or_group O O O O O B-lipid O