Whereas the Jak kinases Jak1 and Jak3 and the signal transducer and activator of transcription proteins Stat3 and Stat5 are activated in normal T cells in response to IL-2 , this signaling pathway was constitutively activated in HTLV-I -transformed cells .
whereas the jak kinases jak1 and jak3 and the signal transducer and activator of transcription proteins stat3 and stat5 are activated in normal t cells in response to il-2 , this signaling pathway was constitutively activated in htlv-i -transformed cells .
O O B-protein_family_or_group I-protein_family_or_group B-protein_molecule O B-protein_molecule O O O O O O O B-protein_family_or_group I-protein_family_or_group B-protein_molecule O B-protein_molecule O O O B-cell_type B-cell_type I-cell_type O O O B-protein_molecule O O O O O O O O B-virus O O O