Mutation of the TCF-1 alpha binding site diminished enhancer activity and disrupted the synergism observed in vivo between tandem enhancer repeats .
mutation of the tcf-1 alpha binding site diminished enhancer activity and disrupted the synergism observed in vivo between tandem enhancer repeats .
O O O B-protein_molecule I-protein_molecule O O O B-other_name I-other_name O O O O O O O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O