The chimeric oncoprotein E2A-HLF , generated by the t ( 17 ; 19 ) chromosomal translocation in pro-B-cell acute lymphoblastic leukemia , incorporates the transactivation domains of E2A and the basic leucine zipper ( bZIP ) DNA-binding and protein dimerization domain of HLF ( hepatic leukemic factor ) .
the chimeric oncoprotein e2a-hlf , generated by the t ( 17 ; 19 ) chromosomal translocation in pro-b-cell acute lymphoblastic leukemia , incorporates the transactivation domains of e2a and the basic leucine zipper ( bzip ) dna-binding and protein dimerization domain of hlf ( hepatic leukemic factor ) .
O B-protein_family_or_group I-protein_family_or_group B-protein_molecule O O O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O B-other_name I-other_name I-other_name I-other_name O O O B-protein_domain_or_region I-protein_domain_or_region O B-protein_molecule O O O O O O O O O O O O O O B-protein_molecule O B-protein_molecule I-protein_molecule I-protein_molecule O O