Whereas activation of the HIV-1 enhancer following T-cell stimulation is mediated largely through binding of the transcription factor NF-kappa B to two adjacent kappa B sites in the HIV-1 long terminal repeat , activation of the HIV-2 enhancer in monocytes and T cells is dependent on four cis-acting elements : a single kappa B site , two purine-rich binding sites , PuB1 and PuB2 , and a pets site .
whereas activation of the hiv-1 enhancer following t-cell stimulation is mediated largely through binding of the transcription factor nf-kappa b to two adjacent kappa b sites in the hiv-1 long terminal repeat , activation of the hiv-2 enhancer in monocytes and t cells is dependent on four cis-acting elements : a single kappa b site , two purine-rich binding sites , pub1 and pub2 , and a pets site .
O O O O B-virus O O B-other_name I-other_name O O O O O O O B-protein_family_or_group I-protein_family_or_group B-protein_molecule I-protein_molecule O O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O O B-virus O O O O O O O B-virus O O B-cell_type O B-cell_type I-cell_type O O O O B-DNA_domain_or_region I-DNA_domain_or_region O O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O B-DNA_domain_or_region O B-DNA_domain_or_region O O O B-DNA_domain_or_region I-DNA_domain_or_region O