Here we report that sustained high concentrations of Ca2+ , but not transient pulses , are required to maintain NF-AT transcription factors in the nucleus , where they participate in Ca2+ -dependent induction of genes required for lymphocyte activation and proliferation .
here we report that sustained high concentrations of ca2+ , but not transient pulses , are required to maintain nf-at transcription factors in the nucleus , where they participate in ca2+ -dependent induction of genes required for lymphocyte activation and proliferation .
O O O O O O O O B-atom O O O B-other_name I-other_name O O O O O B-protein_family_or_group B-protein_family_or_group I-protein_family_or_group O O O O O O O O B-atom O O O B-DNA_family_or_group O O B-cell_type O O B-other_name O