We now demonstrate that a forced exogenous expression of the four different isoforms of WT1 in K562 does not affect the differentiation response , as judged by accumulation of hemoglobin in response to hemin or the expression of megakaryocytic cell surface markers in response to 12-O-tetradecanoylphorbol-13-acetate ( TPA ) .
we now demonstrate that a forced exogenous expression of the four different isoforms of wt1 in k562 does not affect the differentiation response , as judged by accumulation of hemoglobin in response to hemin or the expression of megakaryocytic cell surface markers in response to 12-o-tetradecanoylphorbol-13-acetate ( tpa ) .
O O O O O O B-other_name I-other_name O O O O O O B-DNA_domain_or_region O B-cell_line O O O O B-other_name I-other_name O O O O O O B-protein_complex O O O B-protein_molecule O O O O B-protein_family_or_group I-protein_family_or_group I-protein_family_or_group I-protein_family_or_group O O O B-other_organic_compound O B-other_organic_compound O O