As shown by a methylation interference analysis and oligonucleotide competition experiments , purified NF-kappa B binds at positions -82 to -91 ( GGGAACTACC ) of the GM-CSF promoter sequence with an affinity similar to that with which it binds to the biologically functional kappa B motif in the beta interferon promoter ( GGGAAATTCC ) .
as shown by a methylation interference analysis and oligonucleotide competition experiments , purified nf-kappa b binds at positions -82 to -91 ( gggaactacc ) of the gm-csf promoter sequence with an affinity similar to that with which it binds to the biologically functional kappa b motif in the beta interferon promoter ( gggaaattcc ) .
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