These results suggest that suppression of calcineurin and NFAT activation is a mechanism by which oxidative stress inhibits FasL induction in activated NK cells and further support the hypothesis that thiol-reducing compounds might be required for maintenance of optimal NK functions under physiologic oxidative conditions .
these results suggest that suppression of calcineurin and nfat activation is a mechanism by which oxidative stress inhibits fasl induction in activated nk cells and further support the hypothesis that thiol-reducing compounds might be required for maintenance of optimal nk functions under physiologic oxidative conditions .
O O O O O O B-protein_molecule O B-protein_family_or_group O O O O O O B-other_name I-other_name O B-protein_molecule O O B-cell_type B-cell_type I-cell_type O O O O O O B-other_organic_compound I-other_organic_compound O O O O O O O B-other_name I-other_name O B-other_name I-other_name I-other_name O