Since NF-kappaB/ IkappaB system regulates the transcription of proinflammatory genes , including those responsible for ROS generation , we tested the hypothesis that hydrocortisone may stimulate IkappaB production thus inhibiting NF-kappaB translocation from the cytosol into the nucleus in MNC , in vivo .
since nf-kappab/ ikappab system regulates the transcription of proinflammatory genes , including those responsible for ros generation , we tested the hypothesis that hydrocortisone may stimulate ikappab production thus inhibiting nf-kappab translocation from the cytosol into the nucleus in mnc , in vivo .
O O B-protein_molecule O O O O O B-protein_family_or_group I-protein_family_or_group O O O O O B-inorganic O O O O O O O B-lipid O O B-protein_molecule O O O B-protein_complex O O O B-cell_component O O B-cell_component O B-cell_type O O O O