Remarkably , we observed that these samples displayed a persistent expression of the c-fos protooncogene , associated to an increased AP-1 DNA-binding activity , whereas no variations of CREB or NF-kB were detected .
remarkably , we observed that these samples displayed a persistent expression of the c-fos protooncogene , associated to an increased ap-1 dna-binding activity , whereas no variations of creb or nf-kb were detected .
O O O O O O O O O O O O O B-DNA_domain_or_region I-DNA_domain_or_region O O O O O B-protein_molecule O O O O O O O B-protein_molecule O B-protein_molecule O O O