Extinction of immunoglobulin gene expression in B cells upon fusion with HeLa cells is preceded by rapid nuclear depletion of essential transcription factors and is accompanied by widespread inactivation of genes expressed in a B cell-specific manner .
extinction of immunoglobulin gene expression in b cells upon fusion with hela cells is preceded by rapid nuclear depletion of essential transcription factors and is accompanied by widespread inactivation of genes expressed in a b cell-specific manner .
O O B-DNA_family_or_group I-DNA_family_or_group O O B-cell_type I-cell_type O O O B-cell_line I-cell_line O O O O B-other_name I-other_name O B-protein_family_or_group I-protein_family_or_group I-protein_family_or_group O O O O O O O O O O O B-other_name I-other_name I-other_name O