The ability of ascorbate to enhance cytoplasmic inhibitory IkBalpha protein degradation correlates completely with its capacity to induce NF-kappaB binding to DNA and to potentiate NF-kappaB -mediated transactivation of the HIV-1 long terminal repeat promoter in TNF-alpha -stimulated Jurkat cells but not in cells stimulated with PMA plus ionomycin .
the ability of ascorbate to enhance cytoplasmic inhibitory ikbalpha protein degradation correlates completely with its capacity to induce nf-kappab binding to dna and to potentiate nf-kappab -mediated transactivation of the hiv-1 long terminal repeat promoter in tnf-alpha -stimulated jurkat cells but not in cells stimulated with pma plus ionomycin .
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