Rapid and strong induction of promoter activity was lost in constructs with a mutant AP-1 element ; however , at 16-96 h post-PMA , the mutant collagenase-1 promoter displayed AP-1 independent PMA-mediated transactivation .
rapid and strong induction of promoter activity was lost in constructs with a mutant ap-1 element ; however , at 16-96 h post-pma , the mutant collagenase-1 promoter displayed ap-1 independent pma-mediated transactivation .
O O O O O B-other_name I-other_name O O O O O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O O O O B-other_name I-other_name I-other_name O O B-DNA_domain_or_region B-protein_molecule O O B-protein_molecule O O O O