DESIGN : Retrospective study based on immunohistochemistry and in situ hybridization to detect EBV replicative gene products in tissue samples from patients affected by ARNHL and correlation with CD4+ cell counts and results of EBV serology ( including anti- ZEBRA activity ) in sera from the same patients .
design : retrospective study based on immunohistochemistry and in situ hybridization to detect ebv replicative gene products in tissue samples from patients affected by arnhl and correlation with cd4+ cell counts and results of ebv serology ( including anti- zebra activity ) in sera from the same patients .
O O O O O O B-other_name O O O O O O B-virus O O O O O O O B-multi_cell O O B-other_name O O O B-protein_molecule O O O O O B-virus O O O B-other_name B-protein_molecule O O O B-tissue O O O B-multi_cell O