Hypoxic endothelia showed a > 10-fold increase in sensitivity to inhibitors of proteasome activation , and combinations of hypoxia and LPS enhanced proteasome -dependent cytoplasmic-to-nuclear localization of the nuclear transcription factor-kappa B p65 ( Rel A ) subunit .
hypoxic endothelia showed a > 10-fold increase in sensitivity to inhibitors of proteasome activation , and combinations of hypoxia and lps enhanced proteasome -dependent cytoplasmic-to-nuclear localization of the nuclear transcription factor-kappa b p65 ( rel a ) subunit .
B-tissue I-tissue O O O O O O O O O O B-protein_complex O O O O O B-other_name O B-lipid O B-protein_complex O O O O O B-protein_subunit I-protein_subunit I-protein_subunit I-protein_subunit I-protein_subunit I-protein_subunit I-protein_subunit I-protein_subunit I-protein_subunit I-protein_subunit O