We have demonstrated that the cross-linking of cell surface CD4 by gp120-anti-gp120 immune complexes or heat-inactivated HIV-1 ( iHIV-1 ) is sufficient to trigger activation signals leading to virus reactivation ( 9 ) .
we have demonstrated that the cross-linking of cell surface cd4 by gp120-anti-gp120 immune complexes or heat-inactivated hiv-1 ( ihiv-1 ) is sufficient to trigger activation signals leading to virus reactivation ( 9 ) .
O O O O O O O B-protein_molecule I-protein_molecule B-protein_molecule O B-protein_complex I-protein_complex I-protein_complex O B-virus B-virus O B-virus O O O O O O O O O B-other_name I-other_name O O O O