However , all 20 cases lacked the t ( 15 ; 17 ) and 17 cases tested lacked the promyelocytic/retinoic acid receptor alpha ( RAR alpha ) fusion transcript in RT-PCR assays ; 12 cases had 46 , XX or 46 , XY karyotypes , whereas 2 cases had abnormalities of chromosome 17q : 1 with del ( 17 ) ( q25 ) and the other with t ( 11 ; 17 ) ( q23 ; q21 ) and the promyelocytic leukemia zinc finger/ RAR alpha fusion transcript .
however , all 20 cases lacked the t ( 15 ; 17 ) and 17 cases tested lacked the promyelocytic/retinoic acid receptor alpha ( rar alpha ) fusion transcript in rt-pcr assays ; 12 cases had 46 , xx or 46 , xy karyotypes , whereas 2 cases had abnormalities of chromosome 17q : 1 with del ( 17 ) ( q25 ) and the other with t ( 11 ; 17 ) ( q23 ; q21 ) and the promyelocytic leukemia zinc finger/ rar alpha fusion transcript .
O O O O O O O O O O O O O O O O O O O B-protein_molecule I-protein_molecule I-protein_molecule I-protein_molecule O B-protein_molecule I-protein_molecule O O O O B-other_name I-other_name O O O O O O O O O O O O O O O O O O O B-DNA_molecule I-DNA_molecule O O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O O O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O O B-RNA_molecule I-RNA_molecule I-RNA_molecule I-RNA_molecule B-protein_molecule I-protein_molecule O O O