Mutants of type 5 adenovirus ( Ad5 ) with reiterated DNA sequences in the E1a region appeared in a human T-lymphocyte cell line , Molt-4 , persistently infected with H5sub304 , a deletion/substitution mutant that has a wild-type phenotype in viral replication .
mutants of type 5 adenovirus ( ad5 ) with reiterated dna sequences in the e1a region appeared in a human t-lymphocyte cell line , molt-4 , persistently infected with h5sub304 , a deletion/substitution mutant that has a wild-type phenotype in viral replication .
O O B-virus I-virus I-virus O B-virus O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O O B-DNA_domain_or_region I-DNA_domain_or_region O O O B-cell_line I-cell_line I-cell_line I-cell_line O B-cell_line O O O O B-virus O O B-virus I-virus O O O B-other_name I-other_name O B-other_name I-other_name O