The evolutionarily conserved N-terminal half of IBR/F harbors the DNA-binding/dimerization domain ( outer limits , 127 to 283 ) , one or several casein kinase II sites ( 37 to 67 ) , and a bipartite nuclear localization signal ( 89 to 106 ) which appears to be necessary for nuclear targeting .
the evolutionarily conserved n-terminal half of ibr/f harbors the dna-binding/dimerization domain ( outer limits , 127 to 283 ) , one or several casein kinase ii sites ( 37 to 67 ) , and a bipartite nuclear localization signal ( 89 to 106 ) which appears to be necessary for nuclear targeting .
O O O B-protein_domain_or_region I-protein_domain_or_region O B-protein_molecule O O B-protein_domain_or_region I-protein_domain_or_region O O O O O O O O O O O O B-protein_domain_or_region I-protein_domain_or_region I-protein_domain_or_region I-protein_domain_or_region O O O O O O O O B-protein_domain_or_region I-protein_domain_or_region I-protein_domain_or_region I-protein_domain_or_region O O O O O O O O O O O B-other_name I-other_name O