Binding of the drug inhibits isomerase activity , but studies with other prolyl isomerase inhibitors and analysis of cyclosporin -resistant mutants in yeast suggest that the effects of the drug result from the formation of an inhibitory complex between the drug and isomerase , and not from inhibition of isomerase activity .
binding of the drug inhibits isomerase activity , but studies with other prolyl isomerase inhibitors and analysis of cyclosporin -resistant mutants in yeast suggest that the effects of the drug result from the formation of an inhibitory complex between the drug and isomerase , and not from inhibition of isomerase activity .
O O O O O B-protein_family_or_group O O O O O O B-other_name B-protein_family_or_group O O O O B-other_organic_compound O O O B-mono_cell O O O O O O O O O O O O O B-protein_complex I-protein_complex O O O O B-protein_family_or_group O O O O O O B-protein_family_or_group O O