Whereas TPCK inhibits phosphorylation of I kappa B and , consequently , activation of NF-kappa B , it markedly enhances the activity of JNK , the MAP kinase-related kinase that phosphorylates the transactivation domain of c-Jun .
whereas tpck inhibits phosphorylation of i kappa b and , consequently , activation of nf-kappa b , it markedly enhances the activity of jnk , the map kinase-related kinase that phosphorylates the transactivation domain of c-jun .
O B-protein_molecule O B-other_name O B-protein_molecule I-protein_molecule I-protein_molecule O O O O B-other_name O B-protein_molecule I-protein_molecule O O O O O O O B-protein_molecule O O B-protein_molecule I-protein_molecule I-protein_molecule O O O B-protein_domain_or_region I-protein_domain_or_region O B-protein_molecule O