Therefore , we investigated whether IVS1-10T-->C deleteriously affected BRCA1 splicing or expression , and thereby inactivated the other BRCA1 allele .
therefore , we investigated whether ivs1-10t-->c deleteriously affected brca1 splicing or expression , and thereby inactivated the other brca1 allele .
O O O O O B-other_name O O B-DNA_domain_or_region O O O O O O O O O B-DNA_domain_or_region O O