Insertion of this chimeric promoter ( ISG15 LTR ) upstream of the human IFNA2 gene directed high levels of IFN synthesis in Tat-expressing cells , while this promoter was not responsive to tumor necrosis factor alpha -mediated activation .
insertion of this chimeric promoter ( isg15 ltr ) upstream of the human ifna2 gene directed high levels of ifn synthesis in tat-expressing cells , while this promoter was not responsive to tumor necrosis factor alpha -mediated activation .
O O O B-DNA_family_or_group I-DNA_family_or_group O B-DNA_domain_or_region I-DNA_domain_or_region O O O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O O O O B-protein_family_or_group O O B-cell_line I-cell_line O O O O O O O O B-protein_molecule I-protein_molecule I-protein_molecule I-protein_molecule O O O