Although subtle gene movements within those defined topographical regions cannot be excluded by this study , the results indicate that tissue specificity of gene expression is not accompanied by drastic changes in gene nuclear topography , rather suggesting that gene organization within the nucleus may be primarily dependent on structural constraints imposed on the respective chromosomes .
although subtle gene movements within those defined topographical regions cannot be excluded by this study , the results indicate that tissue specificity of gene expression is not accompanied by drastic changes in gene nuclear topography , rather suggesting that gene organization within the nucleus may be primarily dependent on structural constraints imposed on the respective chromosomes .
O O B-other_name I-other_name O O O B-other_name I-other_name O O O O O O O O O O O O O O B-other_name I-other_name O O O O O O O B-other_name I-other_name I-other_name O O O O B-other_name I-other_name O O B-cell_component O O O O O O O O O O O B-DNA_molecule O