In view of the therapeutic efficiency of glucocorticoids in AD and findings of abnormal cAMP and cAMP-phosphodiesterase activity , the elevated GR concentrations in AD lend support to the hypothesis of a compensatory GR upregulation due to an insufficient action of endogenous cortisol or to altered cAMP -induced GR expression .
in view of the therapeutic efficiency of glucocorticoids in ad and findings of abnormal camp and camp-phosphodiesterase activity , the elevated gr concentrations in ad lend support to the hypothesis of a compensatory gr upregulation due to an insufficient action of endogenous cortisol or to altered camp -induced gr expression .
O O O O B-other_name I-other_name O B-lipid O B-other_name O O O O O O O O O O O B-protein_family_or_group O O B-other_name O O O O O O O O B-protein_family_or_group O O O O O O O B-lipid I-lipid O O O B-nucleotide O B-protein_family_or_group O O