Both IL-4 and anti- CD40 mAb induced activation of phosphatidylinositol 3-kinase ( PI3-kinase ) , translocation of a zeta isoform of protein kinase C , and nuclear expression of NF-kappa B .
both il-4 and anti- cd40 mab induced activation of phosphatidylinositol 3-kinase ( pi3-kinase ) , translocation of a zeta isoform of protein kinase c , and nuclear expression of nf-kappa b .
O B-protein_molecule O O B-protein_molecule O O O O B-protein_molecule I-protein_molecule O B-protein_molecule O O O O O O O O B-protein_molecule I-protein_molecule I-protein_molecule O O O O O B-protein_complex I-protein_complex O