Therefore , although PU . 1 and Spi-B may bind to similar DNA control elements and have redundancy of transactivation function in vitro , the lack of significant levels of Spi-B in myeloid cells makes it unlikely that Spi-B plays a significant role in myeloid lineage development and gene expression .
therefore , although pu . 1 and spi-b may bind to similar dna control elements and have redundancy of transactivation function in vitro , the lack of significant levels of spi-b in myeloid cells makes it unlikely that spi-b plays a significant role in myeloid lineage development and gene expression .
O O O B-protein_molecule I-protein_molecule I-protein_molecule O B-protein_molecule O O O O O O O O O O O B-other_name I-other_name O O O O O O O O O B-protein_molecule O B-cell_type I-cell_type O O O O B-protein_molecule O O O O O B-other_name I-other_name I-other_name O B-other_name I-other_name O