These studies revealed that Calphostin C inhibited the nuclear translocation of the transcription factor activator protein-1 ( AP-1 ) which is considered necessary for FN induction of IL-1beta gene transcription , and prevented the transcription of the IL-1beta gene .
these studies revealed that calphostin c inhibited the nuclear translocation of the transcription factor activator protein-1 ( ap-1 ) which is considered necessary for fn induction of il-1beta gene transcription , and prevented the transcription of the il-1beta gene .
O O O O B-other_organic_compound I-other_organic_compound O O O O O O B-protein_family_or_group I-protein_family_or_group O O O B-protein_molecule O O O O O O B-protein_molecule O O B-protein_molecule O O O O O O O O O B-protein_molecule O O