Results in all cell lines indicated that mutations of the SP1 , TATA and the TAR loop and stem secondary structure resulted in marked decreases in gene expression while mutations of the enhancer motif or TAR primary sequence resulted in only slight decreases .
results in all cell lines indicated that mutations of the sp1 , tata and the tar loop and stem secondary structure resulted in marked decreases in gene expression while mutations of the enhancer motif or tar primary sequence resulted in only slight decreases .
O O O O O O O B-other_name O O B-DNA_domain_or_region O B-DNA_domain_or_region O O B-DNA_substructure I-DNA_substructure O B-DNA_substructure I-DNA_substructure I-DNA_substructure O O O O O B-other_name I-other_name O O O O B-DNA_domain_or_region I-DNA_domain_or_region O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O O O O O O