BACKGROUND : Understanding the mechanism of developmental regulation of hemoglobin switching has scientific as well as clinical relevance because of the influence of fetal hemoglobin ( HbF ) production in adulthood on the clinical manifestation of thalassemia and sickle cell anemia .
background : understanding the mechanism of developmental regulation of hemoglobin switching has scientific as well as clinical relevance because of the influence of fetal hemoglobin ( hbf ) production in adulthood on the clinical manifestation of thalassemia and sickle cell anemia .
O O O O O O O O O B-protein_molecule O O O O O O O O O O O O O B-other_name B-protein_molecule O B-protein_molecule O O O O O O O O O B-other_name O B-other_name I-other_name I-other_name O