Site-directed mutational studies demonstrate that Site I and Site IV together support ATF1- and CREB- induced trans-activation of the H4 promoter .
site-directed mutational studies demonstrate that site i and site iv together support atf1- and creb- induced trans-activation of the h4 promoter .
O O O O O B-DNA_domain_or_region I-DNA_domain_or_region O B-DNA_domain_or_region I-DNA_domain_or_region O O O O O O O O O B-DNA_domain_or_region I-DNA_domain_or_region O