TNFRI has been recently shown to activate NF-kappaB through association with TRADD , RIP , and TRAF2 ; activation of the NF-kappaB -inducing kinase ( NIK ) ; activation of the IkappaB alpha kinases ( IKKalpha and IKKbeta ) ; and phosphorylation of IkappaB alpha .
tnfri has been recently shown to activate nf-kappab through association with tradd , rip , and traf2 ; activation of the nf-kappab -inducing kinase ( nik ) ; activation of the ikappab alpha kinases ( ikkalpha and ikkbeta ) ; and phosphorylation of ikappab alpha .
B-protein_molecule O O O O O O B-protein_complex O O O B-protein_molecule O B-protein_molecule O O B-protein_molecule O O O O B-protein_complex O O O B-protein_molecule O O O O O B-protein_family_or_group I-protein_family_or_group I-protein_family_or_group O B-protein_molecule O B-protein_complex O O O O O B-protein_molecule I-protein_molecule O