The endothelium plays a critical role in inflammation by directing circulating leukocytes into extravascular tissues by expressing adhesive molecules for leukocytes [ e . g . , endothelial-leukocyte adhesion molecule 1 ( ELAM-1 ) and intercellular adhesion molecule 1 ( ICAM-1 ) ] .
the endothelium plays a critical role in inflammation by directing circulating leukocytes into extravascular tissues by expressing adhesive molecules for leukocytes [ e . g . , endothelial-leukocyte adhesion molecule 1 ( elam-1 ) and intercellular adhesion molecule 1 ( icam-1 ) ] .
O O O O O O O O O O B-cell_type I-cell_type O B-tissue I-tissue O O B-protein_molecule I-protein_molecule O B-cell_type O O O O O O B-protein_molecule I-protein_molecule I-protein_molecule I-protein_molecule O B-protein_molecule O O B-protein_molecule I-protein_molecule I-protein_molecule I-protein_molecule O B-protein_molecule O O O