However , an excess of rapamycin is needed to revert FK506 -mediated inhibition of IL-2 production , apoptosis , and transcriptional activation of NF-AT , a T-cell-specific transcription factor necessary for IL-2 gene activation .
however , an excess of rapamycin is needed to revert fk506 -mediated inhibition of il-2 production , apoptosis , and transcriptional activation of nf-at , a t-cell-specific transcription factor necessary for il-2 gene activation .
O O O O O B-other_organic_compound O O O O B-other_organic_compound O O O B-protein_molecule O O B-other_name O O B-other_name I-other_name O B-protein_molecule O O B-protein_family_or_group I-protein_family_or_group I-protein_family_or_group O O B-protein_molecule O O O