Ligation of either CD80 ( B7-1 ) or CD86 ( B7-2 ) , two principal ligands for CD28 , is thought to skew the immune response toward Th1 or Th2 differentiation .
ligation of either cd80 ( b7-1 ) or cd86 ( b7-2 ) , two principal ligands for cd28 , is thought to skew the immune response toward th1 or th2 differentiation .
O O O B-protein_molecule O B-protein_molecule O O B-protein_molecule O B-protein_molecule O O O O O O B-protein_molecule O O O O O O O O O O O O O O