In Jurkat T cells , the ZIP site serves as an activator for IL-2 gene expression , and a combination of ZIP and NFAT binding sites is required for maximal IL-2 promoter activity .
in jurkat t cells , the zip site serves as an activator for il-2 gene expression , and a combination of zip and nfat binding sites is required for maximal il-2 promoter activity .
O B-cell_line I-cell_line I-cell_line O O B-DNA_domain_or_region O O O O O O B-protein_molecule O O O O O O O B-DNA_domain_or_region O B-protein_family_or_group O O O O O O B-protein_molecule O O O