We have identified two human pre-B-cell lines that contain extremely low levels of OTF-2 yet still express high levels of steady-state immunoglobulin heavy-chain mRNA in vivo and efficiently transcribe an immunoglobulin gene in vitro .
we have identified two human pre-b-cell lines that contain extremely low levels of otf-2 yet still express high levels of steady-state immunoglobulin heavy-chain mrna in vivo and efficiently transcribe an immunoglobulin gene in vitro .
O O O O B-cell_line I-cell_line I-cell_line O O O O O O B-protein_family_or_group O O O O O O B-RNA_molecule B-protein_subunit I-protein_subunit O O O O O O O B-DNA_family_or_group I-DNA_family_or_group O O O