These findings demonstrate that interaction of both subunits of the heterodimeric NF-kappa B complex with DNA is required for DNA binding and transcriptional activation and suggest that transcriptional activation mediated by the individual rel-related proteins will differ dramatically , depending on the specific kappa B motifs present .
these findings demonstrate that interaction of both subunits of the heterodimeric nf-kappa b complex with dna is required for dna binding and transcriptional activation and suggest that transcriptional activation mediated by the individual rel-related proteins will differ dramatically , depending on the specific kappa b motifs present .
O O O O O O O O O O B-protein_complex B-protein_complex I-protein_complex I-protein_complex O O O O O B-other_name I-other_name O B-other_name I-other_name O O O B-other_name I-other_name O O O O B-protein_family_or_group I-protein_family_or_group O O O O O O O B-DNA_substructure I-DNA_substructure I-DNA_substructure I-DNA_substructure O O