Mutagenesis of the activator protein-1 [ AP-1 ] site at -72 abolished basal promoter activity and LPS /zymosan inducibility , while mutagenesis of an NF-kappaB-like site at -20 to -10 had no effect .
mutagenesis of the activator protein-1 [ ap-1 ] site at -72 abolished basal promoter activity and lps /zymosan inducibility , while mutagenesis of an nf-kappab-like site at -20 to -10 had no effect .
O O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region B-protein_molecule O O O B-DNA_domain_or_region O B-DNA_domain_or_region I-DNA_domain_or_region O O B-lipid B-other_organic_compound O O O O O O B-DNA_domain_or_region I-DNA_domain_or_region O O O O O O O O