Germline transcripts initiate from promoters upstream of the immunoglobulin switch region , and are necessary to target the appropriate switch region for recombination and switching .
germline transcripts initiate from promoters upstream of the immunoglobulin switch region , and are necessary to target the appropriate switch region for recombination and switching .
B-protein_family_or_group I-protein_family_or_group O O B-DNA_domain_or_region O O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O O O O O O O O O O O B-other_name O O O