We found that NFATx1 DNA binding activity and interaction with AP-1 polypeptides were dependent on its central Rel similarity region and that transcriptional activation was reduced by deletions of either its N-terminal domain or its C-terminal domain , suggesting the presence of intrinsic transcriptional activation motifs in both regions .
we found that nfatx1 dna binding activity and interaction with ap-1 polypeptides were dependent on its central rel similarity region and that transcriptional activation was reduced by deletions of either its n-terminal domain or its c-terminal domain , suggesting the presence of intrinsic transcriptional activation motifs in both regions .
O O O B-protein_molecule O O O O O O B-peptide I-peptide O O O O B-protein_domain_or_region I-protein_domain_or_region I-protein_domain_or_region I-protein_domain_or_region O O B-other_name I-other_name O O O O O O O B-protein_domain_or_region I-protein_domain_or_region O O B-protein_domain_or_region I-protein_domain_or_region O O O O O B-protein_substructure B-other_name I-other_name O O O O O