Our findings support the recently determined calcineurin X-ray crystal structure , provide evidence that calcineurin is the only CsA -sensitive component limiting signaling from the T cell receptor to the nucleus , and suggest a means to render cells and tissues resistant to the toxic side effects of CsA and FK506 .
our findings support the recently determined calcineurin x-ray crystal structure , provide evidence that calcineurin is the only csa -sensitive component limiting signaling from the t cell receptor to the nucleus , and suggest a means to render cells and tissues resistant to the toxic side effects of csa and fk506 .
O O O O O O B-protein_molecule B-other_name I-other_name I-other_name O O O O B-protein_molecule O O O B-other_organic_compound O O O O O O B-protein_family_or_group I-protein_family_or_group I-protein_family_or_group O O B-cell_component O O O O O O O O O O O O O B-other_name I-other_name I-other_name O B-other_organic_compound O B-other_organic_compound O