Next , we demonstrated that these viral ligands directly up-regulated monocyte gene expression upon their binding to their appropriate cellular receptors .
next , we demonstrated that these viral ligands directly up-regulated monocyte gene expression upon their binding to their appropriate cellular receptors .
O O O O O O O O O B-other_name I-other_name B-other_organic_compound I-other_organic_compound O O O O O O O O O