The low frequency with which these Ig-expressing hybrids are recovered , along with the fact that cell fusions can lead to chromosome loss , led us to propose that this rare phenotype was due to loss of a T-cell-derived chromosome encoding a factor or factors with gene silencing activity .
the low frequency with which these ig-expressing hybrids are recovered , along with the fact that cell fusions can lead to chromosome loss , led us to propose that this rare phenotype was due to loss of a t-cell-derived chromosome encoding a factor or factors with gene silencing activity .
O O O O O O B-cell_line I-cell_line O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O B-protein_family_or_group I-protein_family_or_group I-protein_family_or_group I-protein_family_or_group I-protein_family_or_group O O O B-other_name I-other_name I-other_name O