Our results implicate NFIL3/E4BP4 ( nuclear factor regulated by IL-3 /adenovirus E4 promoter binding protein ) in a distinct growth factor-regulated signaling pathway that is responsible for the survival of early B-cell progenitors , and whose alteration by E2A-HLF leads to childhood B lineage leukemia .
our results implicate nfil3/e4bp4 ( nuclear factor regulated by il-3 /adenovirus e4 promoter binding protein ) in a distinct growth factor-regulated signaling pathway that is responsible for the survival of early b-cell progenitors , and whose alteration by e2a-hlf leads to childhood b lineage leukemia .
O O O B-protein_molecule O B-protein_molecule I-protein_molecule I-protein_molecule I-protein_molecule B-protein_molecule O O O O O O O O O O B-other_name I-other_name I-other_name O O O O O O O B-cell_type I-cell_type I-cell_type O O O O O B-protein_molecule O O B-other_name I-other_name I-other_name I-other_name O