Taken together , these data point to a potential mechanism underlying EBV -mediated B cell transformation whereby constitutive induction of key cell cycle regulators by LMP-1 can lead to pRb hyperphosphorylation and uncontrolled cell proliferation .
taken together , these data point to a potential mechanism underlying ebv -mediated b cell transformation whereby constitutive induction of key cell cycle regulators by lmp-1 can lead to prb hyperphosphorylation and uncontrolled cell proliferation .
O O O O O O O O O O O B-virus O O O O O O O O B-protein_family_or_group I-protein_family_or_group I-protein_family_or_group I-protein_family_or_group O B-protein_molecule O O O B-protein_molecule O O B-other_name I-other_name I-other_name O