Activation of NF-kappa B seems to play an important role in the regulation of many proinflammatory cytokine genes , but cannot be the only mechanism , since several cytokine genes lack respective binding sites in their promoter regions .
activation of nf-kappa b seems to play an important role in the regulation of many proinflammatory cytokine genes , but cannot be the only mechanism , since several cytokine genes lack respective binding sites in their promoter regions .
O O B-protein_complex I-protein_complex O O O O O O O O O O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O O O O O O O O O O B-DNA_family_or_group I-DNA_family_or_group O O B-DNA_domain_or_region I-DNA_domain_or_region O O B-DNA_domain_or_region I-DNA_domain_or_region O