Whereas PHA -induced proliferation of PBMCs derived from patients with breast cancer preoperatively was significantly decreased when compared with data obtained in healthy control individuals ( P < 0 . 001 ) , the degree of the defect in PHA -induced proliferation of PBMCs depended upon the tumour burden as manifested by tumour size and axillary lymph node involvement ( P < 0 . 003 in each case ) .
whereas pha -induced proliferation of pbmcs derived from patients with breast cancer preoperatively was significantly decreased when compared with data obtained in healthy control individuals ( p < 0 . 001 ) , the degree of the defect in pha -induced proliferation of pbmcs depended upon the tumour burden as manifested by tumour size and axillary lymph node involvement ( p < 0 . 003 in each case ) .
O B-protein_molecule O O O B-cell_type O O B-multi_cell O B-other_name I-other_name O O O O O O O O O O B-multi_cell I-multi_cell I-multi_cell O O O O O O O O O O O O O O B-protein_molecule O O O B-cell_type O O O O O O O O B-other_name I-other_name O B-body_part I-body_part I-body_part O O O O O O O O O O O O