A highly conserved 19-bp element located immediately 5' of the human GM-CSF TATA box ( bp -34 to -52 ) , herein called purine box 1 ( PB1 ) , has been shown to bind a T-cell nuclear protein complex and to be required for transcriptional induction of the GM-CSF gene following T-cell activation .
a highly conserved 19-bp element located immediately 5' of the human gm-csf tata box ( bp -34 to -52 ) , herein called purine box 1 ( pb1 ) , has been shown to bind a t-cell nuclear protein complex and to be required for transcriptional induction of the gm-csf gene following t-cell activation .
O O O O O O O O O O B-DNA_domain_or_region B-protein_molecule O O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O O O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O B-DNA_domain_or_region O O O O O O O O B-protein_complex I-protein_complex I-protein_complex I-protein_complex O O O O O B-other_name I-other_name O O B-protein_molecule O O B-other_name I-other_name O