Emphasis is placed on cytokines that have been studied in periodontitis , principally TNF-alpha , IL-1 , IL-6 , IL-8 and beta-interferon .
emphasis is placed on cytokines that have been studied in periodontitis , principally tnf-alpha , il-1 , il-6 , il-8 and beta-interferon .
O O O O B-protein_family_or_group O O O O O B-tissue O O B-protein_molecule O B-protein_molecule O B-protein_molecule O B-protein_molecule O B-protein_molecule O