In vivo expanded CD4+CD28null and CD8+CD28null T cells uniformly lack alpha- and beta- bound complexes , resembling the pattern seen in chronically activated cells and not of senescent cells .
in vivo expanded cd4+cd28null and cd8+cd28null t cells uniformly lack alpha- and beta- bound complexes , resembling the pattern seen in chronically activated cells and not of senescent cells .
O O O O O O O O O O O O O O O O O O O O O B-cell_type I-cell_type I-cell_type O O O B-cell_type I-cell_type O