In the present study , we have identified a cellular context ( the interleukin-2 [ IL-2 ] -dependent HT-2 line ) in which the EPO stimulation of the EPOR fails to support cellular proliferation , STAT-5 induction , or MAPK activation , despite efficient phosphorylation of the EPOR and JAK2 and inhibition of apoptosis after withdrawal of IL-2 .
in the present study , we have identified a cellular context ( the interleukin-2 [ il-2 ] -dependent ht-2 line ) in which the epo stimulation of the epor fails to support cellular proliferation , stat-5 induction , or mapk activation , despite efficient phosphorylation of the epor and jak2 and inhibition of apoptosis after withdrawal of il-2 .
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