Similar arrays of functionally important NF-kappaB/NFAT and Ets binding sites are present in the transcriptional enhancers of human immunodeficiency viruses types 1 and 2 ( HIV-1 and HIV-2 ) , suggesting that this pattern of nuclear protein binding sites reflects an evolutionarily conserved mechanism for regulating inducible T-cell gene expression that has been co-opted during HIV evolution .
similar arrays of functionally important nf-kappab/nfat and ets binding sites are present in the transcriptional enhancers of human immunodeficiency viruses types 1 and 2 ( hiv-1 and hiv-2 ) , suggesting that this pattern of nuclear protein binding sites reflects an evolutionarily conserved mechanism for regulating inducible t-cell gene expression that has been co-opted during hiv evolution .
O O O O O O O O O O O O O O B-DNA_domain_or_region I-DNA_domain_or_region O O O O O O O O O B-virus O B-virus O O O O O O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O O O O O O O O B-other_name I-other_name I-other_name O O O O O B-other_name I-other_name O