CTLA-4 ligation inhibited CD3/ CD28 -induced IL-2 mRNA accumulation by inhibiting IL-2 transcription , which appears to be mediated in part through decreasing NF-AT accumulation in the nuclei .
ctla-4 ligation inhibited cd3/ cd28 -induced il-2 mrna accumulation by inhibiting il-2 transcription , which appears to be mediated in part through decreasing nf-at accumulation in the nuclei .
B-protein_molecule O O B-other_name B-protein_molecule O B-protein_molecule O O O O B-protein_molecule O O O O O O O O O O O B-protein_molecule O O O B-cell_component O