Functional analysis of 5' deletion constructs in transfected K562 cells and gel mobility shift localized the major phorbol ester -responsive motifs in the thromboxane receptor gene promoter to a cluster of activator protein-2 ( AP-2 ) binding consensus sites located approximately 1 . 8 kb 5' from the transcription initiation site .
functional analysis of 5' deletion constructs in transfected k562 cells and gel mobility shift localized the major phorbol ester -responsive motifs in the thromboxane receptor gene promoter to a cluster of activator protein-2 ( ap-2 ) binding consensus sites located approximately 1 . 8 kb 5' from the transcription initiation site .
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