Several distinct roles for hsp90 in modulating dioxin receptor function are therefore likely : correct folding of the ligand-binding domain , interference with Arnt heterodimerization , and folding of a DNA-binding conformation of the bHLH domain .
several distinct roles for hsp90 in modulating dioxin receptor function are therefore likely : correct folding of the ligand-binding domain , interference with arnt heterodimerization , and folding of a dna-binding conformation of the bhlh domain .
O O O O B-protein_molecule O O B-inorganic O O O O O O O O O O O O O O O B-protein_molecule O O O O O O O O O O B-protein_domain_or_region I-protein_domain_or_region O