The binding sites fulfil the required criteria for specific steroid binding sites however differ somewhat from the classic androgen receptors from genital skin fibroblast : in fertile adult males ( n = 20 ) the binding sites showed ( 1 ) a high affinity for testosterone ( 1 . 32 +/- 0 . 49 nM ; mean +/- SD ) , ( 2 ) a saturable capacity ( 184 +/- 52 binding sites per cell ; mean +/- SD ) , and ( 3 ) a characteristic competitive binding profile for other steroid hormones ( relative binding affinities : testosterone = dihydrotestosterone > 17 beta-estradiol > progesterone , whereas aldosterone , 17-hydroxy-progesterone and cortisol did not compete appreciably ) .
the binding sites fulfil the required criteria for specific steroid binding sites however differ somewhat from the classic androgen receptors from genital skin fibroblast : in fertile adult males ( n = 20 ) the binding sites showed ( 1 ) a high affinity for testosterone ( 1 . 32 +/- 0 . 49 nm ; mean +/- sd ) , ( 2 ) a saturable capacity ( 184 +/- 52 binding sites per cell ; mean +/- sd ) , and ( 3 ) a characteristic competitive binding profile for other steroid hormones ( relative binding affinities : testosterone = dihydrotestosterone > 17 beta-estradiol > progesterone , whereas aldosterone , 17-hydroxy-progesterone and cortisol did not compete appreciably ) .
O B-protein_domain_or_region I-protein_domain_or_region O O O O O O B-protein_domain_or_region I-protein_domain_or_region I-protein_domain_or_region O O O O O O B-protein_family_or_group I-protein_family_or_group O B-cell_type I-cell_type I-cell_type O O B-multi_cell I-multi_cell I-multi_cell O O O O O O B-protein_domain_or_region I-protein_domain_or_region O O O O O O O O B-lipid O O O O O O O O O O O O O O O O O O O O O O O O O B-protein_domain_or_region I-protein_domain_or_region O O O O O O O O O O O O O O O O O O O B-lipid I-lipid O O O O O B-lipid O B-lipid O B-lipid I-lipid O B-lipid O O O O B-lipid O O O O O O O O