Cotransfection of an hGATA-3 expression plasmid with a reporter plasmid whose transcription is directed by the HIV-1 LTR resulted in 6- to 10-fold stimulation of LTR -mediated transcription , whereas site specific mutation of these GATA sites resulted in virtual abrogation of the activation by hGATA-3 .
cotransfection of an hgata-3 expression plasmid with a reporter plasmid whose transcription is directed by the hiv-1 ltr resulted in 6- to 10-fold stimulation of ltr -mediated transcription , whereas site specific mutation of these gata sites resulted in virtual abrogation of the activation by hgata-3 .
O O O B-DNA_molecule I-DNA_molecule I-DNA_molecule O O B-DNA_molecule I-DNA_molecule O O O O O O B-DNA_domain_or_region I-DNA_domain_or_region O O O O O O O B-DNA_domain_or_region O O O O B-other_name I-other_name I-other_name O O B-DNA_domain_or_region I-DNA_domain_or_region O O O O O O O O B-protein_family_or_group O