Furthermore , when human IL-2R beta was stably expressed in murine BA/F3 cells , robust IL-2 -induced proliferation and JAK3 activation occurred without detectable involvement of either JAK1 , JAK2 or TYK2 .
furthermore , when human il-2r beta was stably expressed in murine ba/f3 cells , robust il-2 -induced proliferation and jak3 activation occurred without detectable involvement of either jak1 , jak2 or tyk2 .
O O O B-protein_molecule B-protein_molecule O O O O O B-cell_line I-cell_line I-cell_line O O B-protein_molecule O O O B-protein_molecule O O O O O O O B-protein_molecule O B-protein_molecule O B-protein_molecule O