Similarly , in transfection experiments in which the selective kappa B binding sites were used to drive the expression of a chloramphenicol acetyltransferase reporter construct , the p65 -and p50 -selected motifs were activated only in the presence of p65 and p50/65 ( a chimeric protein with the p50 DNA binding domain and p65 activation domain ) expression vectors , respectively , and neither demonstrated a significant response to stimuli that induce NF-kappa B activity .
similarly , in transfection experiments in which the selective kappa b binding sites were used to drive the expression of a chloramphenicol acetyltransferase reporter construct , the p65 -and p50 -selected motifs were activated only in the presence of p65 and p50/65 ( a chimeric protein with the p50 dna binding domain and p65 activation domain ) expression vectors , respectively , and neither demonstrated a significant response to stimuli that induce nf-kappa b activity .
O O O O O O O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O O O O O O O O B-protein_molecule I-protein_molecule O O O O B-protein_subunit O B-protein_subunit O O O O O O O O O B-protein_subunit O B-protein_molecule O O B-protein_family_or_group I-protein_family_or_group O O B-protein_subunit O O O O B-protein_subunit O O O O O O O O O O O O O O O O O O B-protein_molecule I-protein_molecule O O