The vpr product of the human immunodeficiency virus type 1 ( HIV-1 ) acts in trans to accelerate virus replication and cytopathic effect in T cells .
the vpr product of the human immunodeficiency virus type 1 ( hiv-1 ) acts in trans to accelerate virus replication and cytopathic effect in t cells .
O B-protein_family_or_group I-protein_family_or_group O O B-virus I-virus I-virus O O O B-virus O O O O O O B-other_name I-other_name O B-other_name I-other_name O B-cell_type I-cell_type O