Where this function of the tumor suppressor proteins is impaired , the capacity for differentiation is lost , which leads to the sustained proliferation that is characteristic of the cancer cell .
where this function of the tumor suppressor proteins is impaired , the capacity for differentiation is lost , which leads to the sustained proliferation that is characteristic of the cancer cell .
O O O O O B-protein_family_or_group I-protein_family_or_group I-protein_family_or_group O O O O O O O O O O O O O O O O O O O O O B-cell_type I-cell_type O