They inhibit synthesis of almost all known cytokines and of several cell surface molecules required for immune function , but the mechanism underlying this activity has been unclear . Here it is shown that glucocorticoids are potent inhibitors of nuclear factor kappa B ( NF-kappa B ) activation in mice and cultured cells .
they inhibit synthesis of almost all known cytokines and of several cell surface molecules required for immune function , but the mechanism underlying this activity has been unclear . here it is shown that glucocorticoids are potent inhibitors of nuclear factor kappa b ( nf-kappa b ) activation in mice and cultured cells .
O O O O O O O B-protein_family_or_group O O O B-protein_family_or_group I-protein_family_or_group I-protein_family_or_group O O B-other_name I-other_name O O O O O O O O O O O O O O O O B-lipid O O B-other_name O B-protein_molecule I-protein_molecule I-protein_molecule I-protein_molecule O B-protein_molecule I-protein_molecule O O O B-multi_cell O B-cell_line I-cell_line O