Mutations in these liver -enriched transcription factors result in two forms of early-onset type 2 diabetes ( maturity-onset diabetes of the young [ MODY ] ) , MODY3 and MODY1 , which are characterized by impaired glucose-stimulated insulin secretion , early disease onset , and autosomal dominant inheritance .
mutations in these liver -enriched transcription factors result in two forms of early-onset type 2 diabetes ( maturity-onset diabetes of the young [ mody ] ) , mody3 and mody1 , which are characterized by impaired glucose-stimulated insulin secretion , early disease onset , and autosomal dominant inheritance .
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