The close homology of the basic region/leucine zipper ( bZIP ) DNA-binding and dimerization domain of HLF to that of the CES-2 cell-death specification protein of Caenorhabditis elegans suggests a model of leukaemogenesis in which E2A-HLF blocks an early step within an evolutionarily conserved cell-death pathway .
the close homology of the basic region/leucine zipper ( bzip ) dna-binding and dimerization domain of hlf to that of the ces-2 cell-death specification protein of caenorhabditis elegans suggests a model of leukaemogenesis in which e2a-hlf blocks an early step within an evolutionarily conserved cell-death pathway .
O O O O O B-protein_domain_or_region I-protein_domain_or_region I-protein_domain_or_region O B-protein_domain_or_region O O O B-protein_domain_or_region I-protein_domain_or_region O B-protein_family_or_group O O O O B-protein_molecule I-protein_molecule I-protein_molecule I-protein_molecule O B-multi_cell I-multi_cell O O O O B-other_name O O B-protein_molecule O O O O O O O O B-other_name I-other_name O