We tested the necessity for appropriate spatial alignment of these elements by using mutated enhancers with altered spacings .
we tested the necessity for appropriate spatial alignment of these elements by using mutated enhancers with altered spacings .
O O O O O O B-other_name I-other_name O O B-DNA_family_or_group O O B-DNA_family_or_group I-DNA_family_or_group O O O O