As AP-1 activity is regulated in part by activation of the c-Jun N-terminal kinase ( JNK ) , which phosphorylates and subsequently increases the transcriptional activity of c-Jun , we examined whether LPS treatment of macrophages resulted in activation of this kinase .
as ap-1 activity is regulated in part by activation of the c-jun n-terminal kinase ( jnk ) , which phosphorylates and subsequently increases the transcriptional activity of c-jun , we examined whether lps treatment of macrophages resulted in activation of this kinase .
O B-protein_molecule O O O O O O O O O B-protein_molecule I-protein_molecule I-protein_molecule O B-protein_molecule O O O O O O O O O O O O O O O O B-lipid O O B-cell_type O O O O O B-protein_family_or_group O