Moreover , the mechanism of action of BHRF1 resembled that of Bcl-2 and Bcl-xL as it inhibited TNF- and anti-Fas- induced activation of two enzymes participating in the apoptosis pathway , cytosolic phospholipase A2 and caspase-3/CPP32 , but did not interfere with the activation of NF-kappaB -like transcription factors .
moreover , the mechanism of action of bhrf1 resembled that of bcl-2 and bcl-xl as it inhibited tnf- and anti-fas- induced activation of two enzymes participating in the apoptosis pathway , cytosolic phospholipase a2 and caspase-3/cpp32 , but did not interfere with the activation of nf-kappab -like transcription factors .
O O O O O O O B-protein_molecule O O O B-protein_molecule O B-protein_molecule O O O O O O O O O O O O O O B-other_name O O B-protein_molecule I-protein_molecule I-protein_molecule O B-protein_molecule O O O O O O O O O B-protein_complex O O O O