NIK cannot phosphorylate IkappaB -alpha directly , but it appears to be a functionally important subunit , because mutated NIK inhibited stimulus-induced kappaB -dependent transcription more effectively than mutated IKK-alpha or -beta .
nik cannot phosphorylate ikappab -alpha directly , but it appears to be a functionally important subunit , because mutated nik inhibited stimulus-induced kappab -dependent transcription more effectively than mutated ikk-alpha or -beta .
B-protein_molecule O O B-protein_molecule O O O O O O O O O O O O O O O B-protein_molecule O O B-protein_molecule O O O O O O B-protein_molecule O B-protein_molecule O