We conclude , rather , that alpha 4 beta 1 in freshly isolated T cells delivers a distinct signal that synergizes early with signals initiated by TCR/CD3 ligation to induce DNA binding of multiple transcription factors required for cytokine gene induction .
we conclude , rather , that alpha 4 beta 1 in freshly isolated t cells delivers a distinct signal that synergizes early with signals initiated by tcr/cd3 ligation to induce dna binding of multiple transcription factors required for cytokine gene induction .
O O O O O O B-protein_molecule I-protein_molecule I-protein_molecule I-protein_molecule O B-cell_type I-cell_type I-cell_type I-cell_type O O O O O O O O O O O B-protein_complex O O O O O O O B-protein_family_or_group I-protein_family_or_group O O B-DNA_family_or_group I-DNA_family_or_group O O