The E2A-HLF ( hepatic leukemia factor ) oncoprotein , generated in pro-B lymphocytes by fusion of the trans-activation domain of E2A to the basic region/leucine zipper ( bZIP ) domain of HLF , functions as an anti-apoptotic transcription factor in leukemic cell transformation .
the e2a-hlf ( hepatic leukemia factor ) oncoprotein , generated in pro-b lymphocytes by fusion of the trans-activation domain of e2a to the basic region/leucine zipper ( bzip ) domain of hlf , functions as an anti-apoptotic transcription factor in leukemic cell transformation .
O B-protein_molecule I-protein_molecule I-protein_molecule I-protein_molecule I-protein_molecule I-protein_molecule I-protein_molecule O O O B-cell_type I-cell_type O O O O B-protein_domain_or_region I-protein_domain_or_region O B-protein_molecule O O B-protein_domain_or_region I-protein_domain_or_region I-protein_domain_or_region I-protein_domain_or_region B-protein_domain_or_region O O O B-protein_molecule O O O O B-protein_family_or_group I-protein_family_or_group I-protein_family_or_group O B-other_name I-other_name I-other_name O