We conclude that sodium phenylacetate treatment of K562 cells increases gamma-globin mRNA and induces cell maturation as judged by morphology without affecting the expression of the erythroid transcription factors , some of which are known to be involved in the regulation of beta-like globin genes .
we conclude that sodium phenylacetate treatment of k562 cells increases gamma-globin mrna and induces cell maturation as judged by morphology without affecting the expression of the erythroid transcription factors , some of which are known to be involved in the regulation of beta-like globin genes .
O O O B-other_organic_compound I-other_organic_compound O O B-cell_line I-cell_line O B-RNA_molecule I-RNA_molecule O O O O O O O O O O O O O O B-protein_family_or_group B-protein_family_or_group I-protein_family_or_group O O O O O O O O O O O O O B-DNA_family_or_group I-DNA_family_or_group I-DNA_family_or_group O