The t ( 17 ; 19 ) translocation in acute lymphoblastic leukemias results in creation of E2A- hepatic leukemia factor ( HLF ) chimeric proteins that contain the DNA-binding and protein dimerization domains of the basic leucine zipper ( bZIP ) protein HLF fused to a portion of E2A proteins with transcriptional activation properties .
the t ( 17 ; 19 ) translocation in acute lymphoblastic leukemias results in creation of e2a- hepatic leukemia factor ( hlf ) chimeric proteins that contain the dna-binding and protein dimerization domains of the basic leucine zipper ( bzip ) protein hlf fused to a portion of e2a proteins with transcriptional activation properties .
O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O O B-other_name I-other_name I-other_name O O O O B-protein_molecule B-protein_molecule I-protein_molecule I-protein_molecule O B-protein_molecule O B-protein_family_or_group I-protein_family_or_group O O O B-protein_domain_or_region I-protein_domain_or_region I-protein_domain_or_region I-protein_domain_or_region I-protein_domain_or_region O O B-protein_family_or_group I-protein_family_or_group I-protein_family_or_group I-protein_family_or_group I-protein_family_or_group I-protein_family_or_group I-protein_family_or_group B-protein_molecule O O O O O B-protein_family_or_group I-protein_family_or_group O B-other_name I-other_name I-other_name O