As2O3 induced PML ( promyelocytic leukemia ) protein degradation but did not modulate expression of cell cycle-related proteins , including c-myc , retinoblastoma protein , cyclin-dependent kinase 4 , cyclin D1 , and p53 , or expression of differentiation-related antigens .
as2o3 induced pml ( promyelocytic leukemia ) protein degradation but did not modulate expression of cell cycle-related proteins , including c-myc , retinoblastoma protein , cyclin-dependent kinase 4 , cyclin d1 , and p53 , or expression of differentiation-related antigens .
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