Our findings demonstrate that p38 MAPK 1 ) plays an important role in signal integration during costimulation of primary mouse T cells , 2 ) may be involved in the induction of c-Jun activation and augmentation of AP-1 transcriptional activity , and 3 ) regulates whether T cells enter a state of functional unresponsiveness .
our findings demonstrate that p38 mapk 1 ) plays an important role in signal integration during costimulation of primary mouse t cells , 2 ) may be involved in the induction of c-jun activation and augmentation of ap-1 transcriptional activity , and 3 ) regulates whether t cells enter a state of functional unresponsiveness .
O O O O B-protein_molecule I-protein_molecule O O O O O O O O O O O O B-cell_type I-cell_type I-cell_type I-cell_type O O O O O O O O O O B-protein_molecule O O O O B-protein_molecule O O O O O O O O B-cell_type I-cell_type O O O O B-other_name I-other_name O