Whereas IL-4 appears to repress functional IL-12 signaling through inhibition of IL-12R beta 2 expression , IFN-gamma in the mouse , and IFN-alpha in the human appear to induce IL-12R beta 2 expression and promote IL-12 responsiveness .
whereas il-4 appears to repress functional il-12 signaling through inhibition of il-12r beta 2 expression , ifn-gamma in the mouse , and ifn-alpha in the human appear to induce il-12r beta 2 expression and promote il-12 responsiveness .
O B-protein_molecule O O O O B-protein_molecule O O O O B-protein_molecule I-protein_molecule I-protein_molecule O O B-protein_molecule O O O O O B-protein_molecule O O O O O O B-protein_molecule I-protein_molecule I-protein_molecule O O O B-protein_molecule O O