On the other hand , the 3'NF-E2/AP1 motif is able to exert both positive and negative regulatory effects on the zeta 2-globin promoter activity in K562 cells , and this dual function appears to be modulated through differential binding of the ubiquitous AP1 factors and the erythroid-enriched NF-E2 factor .
on the other hand , the 3'nf-e2/ap1 motif is able to exert both positive and negative regulatory effects on the zeta 2-globin promoter activity in k562 cells , and this dual function appears to be modulated through differential binding of the ubiquitous ap1 factors and the erythroid-enriched nf-e2 factor .
O O O O O O B-DNA_domain_or_region I-DNA_domain_or_region O O O O O O O O B-other_name I-other_name O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O O B-cell_line I-cell_line O O O O O O O O O O O O O O B-protein_family_or_group I-protein_family_or_group I-protein_family_or_group O O B-protein_molecule I-protein_molecule I-protein_molecule O