Evidence for a role for PKCalpha as an effector of Rho was obtained by the observation that coexpression of the N-terminal domain of PKCalpha blocked the effects of activated Rho plus PMA on AP-1 transcriptional activity .
evidence for a role for pkcalpha as an effector of rho was obtained by the observation that coexpression of the n-terminal domain of pkcalpha blocked the effects of activated rho plus pma on ap-1 transcriptional activity .
O O O O O B-protein_molecule O O O O B-protein_molecule O O O O O O O O O B-protein_domain_or_region I-protein_domain_or_region O B-protein_molecule O O O O O B-protein_molecule O B-other_organic_compound O B-protein_molecule O O O