In particular , naturally occurring sequence variation impacted transcription factor binding to an activating transcription factor/ cAMP response element binding ( ATF/CREB ) binding site ( located between the LEF-1 and distal NF-kappaB transcription factor binding sites ) that we identified in previous studies of the HIV-1 LTR .
in particular , naturally occurring sequence variation impacted transcription factor binding to an activating transcription factor/ camp response element binding ( atf/creb ) binding site ( located between the lef-1 and distal nf-kappab transcription factor binding sites ) that we identified in previous studies of the hiv-1 ltr .
O O O O O B-other_name I-other_name O B-protein_family_or_group I-protein_family_or_group O O O B-protein_molecule I-protein_molecule I-protein_molecule B-polynucleotide O O O O B-protein_molecule O O O O O O O B-protein_molecule O O B-protein_family_or_group O O O O O O O O O O O O O B-virus B-DNA_domain_or_region O