Given the deleterious effects to the host of TNF-alpha , it has been postulated that TNF-alpha gene expression must be tightly regulated .
given the deleterious effects to the host of tnf-alpha , it has been postulated that tnf-alpha gene expression must be tightly regulated .
O O O O O O O O B-protein_molecule O O O O O O B-protein_molecule O O O O O O O