This NF-kappaB binding complex is composed of transcriptionally active p65 ( RelA ) /p50 heterodimers and results primarily from the targeted degradation of IkappaB-alpha , an inhibitor that sequesters Rel/kappaB in the cytoplasm .
this nf-kappab binding complex is composed of transcriptionally active p65 ( rela ) /p50 heterodimers and results primarily from the targeted degradation of ikappab-alpha , an inhibitor that sequesters rel/kappab in the cytoplasm .
O B-protein_complex O O O O O B-protein_complex I-protein_complex I-protein_complex I-protein_complex B-protein_subunit O O O O O O O O O O O B-protein_molecule O O O O O B-protein_family_or_group O O B-cell_component O