Overall therefore , exposure to NSAIDs leads to a profound switch in gene expression in monocytic cells , with suppression of genes involved in macrophage activation and induction of stress genes and HSF1 appears to play a regulatory role in these effects .
overall therefore , exposure to nsaids leads to a profound switch in gene expression in monocytic cells , with suppression of genes involved in macrophage activation and induction of stress genes and hsf1 appears to play a regulatory role in these effects .
O O O O O B-other_organic_compound O O O O O O B-other_name I-other_name O B-cell_type I-cell_type O O O O O O O B-other_name I-other_name O O O B-DNA_family_or_group I-DNA_family_or_group O B-protein_molecule O O O O O O O O O O