Taken together , our studies revealed three unexpected findings which require further analysis : ( 1 ) expression of Id2 mRNA is often associated with lymphocytic transformation by HTLV-I or -II ; ( 2 ) T-cells usually express either Id2 or Id3 mRNA , but B-cells often express both simultaneously ; ( 3 ) non-dividing , normal PBL express high levels of Id2 and no Id3 mRNA ; and with the onset of cellular proliferation , levels of Id2 mRNA decrease while levels of Id3 mRNA increase , suggesting that regulation of expression of these closely related genes is disparate .
taken together , our studies revealed three unexpected findings which require further analysis : ( 1 ) expression of id2 mrna is often associated with lymphocytic transformation by htlv-i or -ii ; ( 2 ) t-cells usually express either id2 or id3 mrna , but b-cells often express both simultaneously ; ( 3 ) non-dividing , normal pbl express high levels of id2 and no id3 mrna ; and with the onset of cellular proliferation , levels of id2 mrna decrease while levels of id3 mrna increase , suggesting that regulation of expression of these closely related genes is disparate .
O O O O O O O O O O O O O O O O O O O B-protein_molecule O O O O O O O O B-virus O O O O O O O O O O B-protein_molecule O B-protein_molecule O O O O O O O O O O O O O O O B-cell_type O O O O B-protein_molecule O O B-protein_molecule O O O O O O O O O O O O B-protein_molecule O O O O O B-protein_molecule O O O O O O O O O O O O B-DNA_family_or_group O O O