In monocytic cells , IL-1beta treatment led to a production of ROIs which is independent of the 5-LOX enzyme but requires the NADPH oxidase activity .
in monocytic cells , il-1beta treatment led to a production of rois which is independent of the 5-lox enzyme but requires the nadph oxidase activity .
O B-cell_type I-cell_type O B-protein_molecule O O O O O O B-inorganic O O O O O B-protein_molecule O O O O B-other_organic_compound O O O