In vitro studies identify three essential elements of the TATA-less blr1 core promoter that confer cell type- and differentiation- specific expression in the B cells of both humans and mice , a functional promoter region ( -36 with respect to the transcription start site ) , a NF-kappaB motif ( +44 ) , and a noncanonical octamer motif ( +157 ) .
in vitro studies identify three essential elements of the tata-less blr1 core promoter that confer cell type- and differentiation- specific expression in the b cells of both humans and mice , a functional promoter region ( -36 with respect to the transcription start site ) , a nf-kappab motif ( +44 ) , and a noncanonical octamer motif ( +157 ) .
O O O O O O O O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O O O O O O O O O O B-cell_type I-cell_type O O B-multi_cell O B-multi_cell O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O O O O O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O O O B-protein_complex O O O O O O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O O O O