In addition , vitamin D -resistant cell nuclear extract contained a protein ( s ) which was bound specifically to the VDRE and was capable of completely inhibiting VDR-RXR- VDRE complex formation ; these effects were not demonstrated with nuclear extract from the wild type cell line or with the post-nuclear extract of the vitamin D -resistant cell line .
in addition , vitamin d -resistant cell nuclear extract contained a protein ( s ) which was bound specifically to the vdre and was capable of completely inhibiting vdr-rxr- vdre complex formation ; these effects were not demonstrated with nuclear extract from the wild type cell line or with the post-nuclear extract of the vitamin d -resistant cell line .
O O O B-lipid I-lipid O O O O O O O O O O O O O O O O B-DNA_domain_or_region O O O O O O B-protein_complex B-DNA_domain_or_region O O O O O O O O O B-cell_component I-cell_component O O B-cell_line I-cell_line I-cell_line I-cell_line O O O B-cell_component I-cell_component O O B-lipid I-lipid O O O O