Two multicopy basal enhancer motifs within the SCMV MIE enhancer , namely , 11 copies of the 16-bp cyclic AMP response element ( CRE ) and 3 copies of novel 17-bp serum response factor ( SRF ) binding sites referred to as the SNE ( SRF/NFkappaB-like element ) , as well as four classical NFkappaB sites within the HCMV version , contribute to TPA responsiveness in transient assays in monocyte and T- cell types .
two multicopy basal enhancer motifs within the scmv mie enhancer , namely , 11 copies of the 16-bp cyclic amp response element ( cre ) and 3 copies of novel 17-bp serum response factor ( srf ) binding sites referred to as the sne ( srf/nfkappab-like element ) , as well as four classical nfkappab sites within the hcmv version , contribute to tpa responsiveness in transient assays in monocyte and t- cell types .
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