The changes in gene expression brought about by gamma interferon are thought to involve transient increases in the activities of cellular protein tyrosine kinases , including the Janus kinases Jak1 and Jak2 , leading to tyrosine phosphorylation of the transcription factor Stat1 .
the changes in gene expression brought about by gamma interferon are thought to involve transient increases in the activities of cellular protein tyrosine kinases , including the janus kinases jak1 and jak2 , leading to tyrosine phosphorylation of the transcription factor stat1 .
O O O B-other_name I-other_name O O O B-protein_family_or_group I-protein_family_or_group O O O O O O O O O O B-protein_family_or_group I-protein_family_or_group B-amino_acid_monomer O O O O B-protein_family_or_group I-protein_family_or_group B-protein_molecule O B-protein_molecule O O O B-amino_acid_monomer O O O B-protein_molecule I-protein_molecule B-protein_family_or_group O