Patients with one type of major histocompatibility complex class II combined immunodeficiency have mutations in a gene termed class II transactivator ( CIITA ) , which coordinately controls the transcription of the three major human class II genes , HLA -DR , -DQ , and -DP .
patients with one type of major histocompatibility complex class ii combined immunodeficiency have mutations in a gene termed class ii transactivator ( ciita ) , which coordinately controls the transcription of the three major human class ii genes , hla -dr , -dq , and -dp .
B-multi_cell O O O O B-protein_complex I-protein_complex I-protein_complex I-protein_complex I-protein_complex O O O O O O O O B-protein_family_or_group I-protein_family_or_group I-protein_family_or_group O B-protein_molecule O O O O O O O O O O O B-DNA_family_or_group I-DNA_family_or_group I-DNA_family_or_group I-DNA_family_or_group O O O O O O O O O