In a 3 day intervention study in which 600 mg of the antioxidant thioctic acid ( alpha-lipoic acid ) per day were given to nine patients with diabetic nephropathy oxidative stress in plasma samples was decreased by 48% and NF-kappaB binding activity in ex vivo isolated peripheral blood mononuclear cells by 38% .
in a 3 day intervention study in which 600 mg of the antioxidant thioctic acid ( alpha-lipoic acid ) per day were given to nine patients with diabetic nephropathy oxidative stress in plasma samples was decreased by 48% and nf-kappab binding activity in ex vivo isolated peripheral blood mononuclear cells by 38% .
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