Inhibition of the NF-kappaB pathway by overexpression of a dominant-active inhibitor of NF-kappaB abolished CD40 -induced up-regulation of both the Bfl-1 and Bcl-x genes and also eliminated the ability of CD40 to rescue Fas -induced cell death .
inhibition of the nf-kappab pathway by overexpression of a dominant-active inhibitor of nf-kappab abolished cd40 -induced up-regulation of both the bfl-1 and bcl-x genes and also eliminated the ability of cd40 to rescue fas -induced cell death .
O O O B-protein_complex O O O O O O O O B-protein_complex O B-protein_molecule O O O O O B-protein_molecule O B-protein_molecule O O O O O O O B-protein_molecule O O B-protein_molecule O O O O