HeLa cells stably or transiently transfected with mutant CIITA constructs showed up to 99% suppression of MHC class II antigen induction by IFN-gamma and marked suppression of HLA-DRA mRNA expression .
hela cells stably or transiently transfected with mutant ciita constructs showed up to 99% suppression of mhc class ii antigen induction by ifn-gamma and marked suppression of hla-dra mrna expression .
B-cell_line I-cell_line O O O O O B-DNA_family_or_group B-protein_molecule O O O O O O O B-protein_family_or_group I-protein_family_or_group I-protein_family_or_group O O O B-protein_molecule O O O O B-RNA_molecule I-RNA_molecule O O