Stimulation of lymphoid cells with interleukin-1beta ( IL-1beta ) led to ROI production and NF-kappaB activation , which could both be blocked by antioxidants or FLAP inhibitors , confirming that 5-LOX was the source of ROIs and was required for NF-kappaB activation in these cells .
stimulation of lymphoid cells with interleukin-1beta ( il-1beta ) led to roi production and nf-kappab activation , which could both be blocked by antioxidants or flap inhibitors , confirming that 5-lox was the source of rois and was required for nf-kappab activation in these cells .
O O B-cell_type I-cell_type O B-protein_molecule O B-protein_molecule O O O O O O B-protein_complex O O O O O O O O O O B-protein_molecule O O O O B-protein_molecule O O O O B-inorganic O O O O B-protein_complex O O O O O