Although three sites in the TNF-alpha promoter ( kappa 1 , kappa 2 , and kappa 3 ) specifically bind the transcription factor NF-kappa B in lymphoid nuclear extracts , TNF-alpha mRNA induction by PMA does not correlate with NF-kappa B binding activities displayed by different T and B cell lines .
although three sites in the tnf-alpha promoter ( kappa 1 , kappa 2 , and kappa 3 ) specifically bind the transcription factor nf-kappa b in lymphoid nuclear extracts , tnf-alpha mrna induction by pma does not correlate with nf-kappa b binding activities displayed by different t and b cell lines .
O O O O O B-protein_molecule O O O O O O O O O O O O O O O B-protein_family_or_group I-protein_family_or_group B-protein_molecule I-protein_molecule O O B-cell_component I-cell_component O B-protein_molecule O O O B-other_organic_compound O O O O B-protein_molecule I-protein_molecule O O O O O O O O O O O