We find that , although the variant octamer motif binds Oct-1 and Oct-2 in vitro with 5-fold lower affinity than the consensus octamer motif , mutation of the variant octamer motif to either a consensus octamer or non- octamer motif has no effect on transcriptional activation from the germline promoter .
we find that , although the variant octamer motif binds oct-1 and oct-2 in vitro with 5-fold lower affinity than the consensus octamer motif , mutation of the variant octamer motif to either a consensus octamer or non- octamer motif has no effect on transcriptional activation from the germline promoter .
O O O O O O O B-DNA_domain_or_region I-DNA_domain_or_region O B-protein_molecule O B-protein_molecule O O O O O O O O B-DNA_domain_or_region B-DNA_domain_or_region I-DNA_domain_or_region O O O O O B-DNA_domain_or_region I-DNA_domain_or_region O O O B-DNA_domain_or_region I-DNA_domain_or_region O B-DNA_family_or_group B-DNA_domain_or_region I-DNA_domain_or_region O O O O B-other_name I-other_name O O B-DNA_domain_or_region I-DNA_domain_or_region O