As neutralizing anti- IL-6 Abs effectively down-regulated the early induction of STAT proteins and as exogenously added IL-6 rapidly activated DNA binding similar to TCR -mediated bindings , it can be concluded that IL-6 is the factor responsible for the activation of STAT proteins in a primary T cell response .
as neutralizing anti- il-6 abs effectively down-regulated the early induction of stat proteins and as exogenously added il-6 rapidly activated dna binding similar to tcr -mediated bindings , it can be concluded that il-6 is the factor responsible for the activation of stat proteins in a primary t cell response .
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