Therefore , IRF-1 may be an important contributor to IL-12 signaling , and we speculate that the defective IL-12 responses seen in IRF -1-/- mice might be attributable , in part , to the absence of this transcription factor .
therefore , irf-1 may be an important contributor to il-12 signaling , and we speculate that the defective il-12 responses seen in irf -1-/- mice might be attributable , in part , to the absence of this transcription factor .
O O B-protein_molecule O O O O O O B-protein_molecule O O O O O O O O B-protein_molecule O O O B-protein_family_or_group O O O O O O O O O O O O O O B-protein_family_or_group I-protein_family_or_group O