Since these latter compounds were known to activate NF-kappa B translocation in a redox-sensitive way , we have demonstrated that NF-kappa B activation by PMA was resistant to antioxidant N-acetyl-L-cysteine ( NAC ) and sensitive to kinase inhibitors staurosporine and H7 while activation by H2O2 or TNF-alpha were not .
since these latter compounds were known to activate nf-kappa b translocation in a redox-sensitive way , we have demonstrated that nf-kappa b activation by pma was resistant to antioxidant n-acetyl-l-cysteine ( nac ) and sensitive to kinase inhibitors staurosporine and h7 while activation by h2o2 or tnf-alpha were not .
O O O O O O O O B-protein_complex I-protein_complex O O O O O O O O O O B-protein_complex I-protein_complex O O B-other_organic_compound O O O B-other_organic_compound B-other_organic_compound O B-other_organic_compound O O O O O O B-other_organic_compound O B-other_organic_compound O O O B-inorganic O B-protein_molecule O O O