Both sIgM- and sIgD- crosslinking with antibodies induced elevation of cAMP levels , phosphatidylinositol turnover , PKC activation and expression of Egr-1 and c-fos mRNA , although sIgM -crosslinking was more effective than sIgD -crosslinking , presumably due to the higher expression of sIgM than of sIgD .
both sigm- and sigd- crosslinking with antibodies induced elevation of camp levels , phosphatidylinositol turnover , pkc activation and expression of egr-1 and c-fos mrna , although sigm -crosslinking was more effective than sigd -crosslinking , presumably due to the higher expression of sigm than of sigd .
O O O O O O O O O O B-nucleotide O O B-lipid O O B-protein_molecule O O O O O O O O O O B-protein_molecule O O O O O B-protein_molecule O O O O O O O O O B-protein_molecule O O B-protein_molecule O