Large or polar substitutions on C-11 of 1 alpha , 25- ( OH ) 2D3 thus impair the binding of the vitamin D receptor but increase the affinity to vitamin D-binding protein .
large or polar substitutions on c-11 of 1 alpha , 25- ( oh ) 2d3 thus impair the binding of the vitamin d receptor but increase the affinity to vitamin d-binding protein .
O O B-other_name I-other_name O B-lipid O B-lipid I-lipid I-lipid I-lipid I-lipid I-lipid I-lipid I-lipid O O O O O O B-lipid I-lipid O O O O O O B-protein_family_or_group I-protein_family_or_group I-protein_family_or_group O