Deletion of all the Sp 1-binding sites from the enhancer reduces transcription by 80-90% in HeLa , as well as in BJA-B cells , whereas the removal of the octamer-binding site reduces transcription to levels below detection in both cell types .
deletion of all the sp 1-binding sites from the enhancer reduces transcription by 80-90% in hela , as well as in bja-b cells , whereas the removal of the octamer-binding site reduces transcription to levels below detection in both cell types .
O O O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O O B-DNA_domain_or_region O O O O O O O O O O O B-cell_line I-cell_line O O O O O O B-DNA_domain_or_region I-DNA_domain_or_region O O O O O O O O O O O