Importantly , two previously characterized mutants with point mutations in Tax , M32 ( Y196A , K197S ) and M41 ( H287A , P288S ) , which were shown to be defective in Tax -activated transcription were unable to interact with TFIIA in this assay .
importantly , two previously characterized mutants with point mutations in tax , m32 ( y196a , k197s ) and m41 ( h287a , p288s ) , which were shown to be defective in tax -activated transcription were unable to interact with tfiia in this assay .
O O O O O B-protein_family_or_group O B-other_name I-other_name O B-protein_molecule O B-protein_molecule O B-amino_acid_monomer O B-amino_acid_monomer O O B-protein_molecule O B-amino_acid_monomer O B-amino_acid_monomer O O O O O O O O O B-protein_molecule O O O O O O O B-protein_molecule O O O O