Tumor cell lines with a defective retinoblastoma gene are unable to transcribe the HLA class II genes in response to IFN-gamma treatment , and reconstitution of functional Rb rescues IFN-gamma-induced class II gene expression .
tumor cell lines with a defective retinoblastoma gene are unable to transcribe the hla class ii genes in response to ifn-gamma treatment , and reconstitution of functional rb rescues ifn-gamma-induced class ii gene expression .
O O O O O O B-other_name O O O O O O B-DNA_family_or_group I-DNA_family_or_group I-DNA_family_or_group I-DNA_family_or_group O O O B-protein_molecule O O O O O O B-protein_molecule O B-other_name B-DNA_family_or_group I-DNA_family_or_group I-DNA_family_or_group O O