Since TNF is one of the major inducers of various adhesion molecules in human endothelial cells and their expression is known to require the activation of NF-kappa B , we examined the effect of PTPase inhibitors on the TNF -mediated induction of intracellular adhesion molecule ( ICAM ) -1 , vascular cell adhesion molecule ( VCAM ) -1 and endothelial leukocyte adhesion molecule ( ELAM ) -1 .
since tnf is one of the major inducers of various adhesion molecules in human endothelial cells and their expression is known to require the activation of nf-kappa b , we examined the effect of ptpase inhibitors on the tnf -mediated induction of intracellular adhesion molecule ( icam ) -1 , vascular cell adhesion molecule ( vcam ) -1 and endothelial leukocyte adhesion molecule ( elam ) -1 .
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