The addition of rCTLA4Ig , which blocks CD28 binding to its ligand , to the cultures decreased IL-2 promoter activation by >80% .
the addition of rctla4ig , which blocks cd28 binding to its ligand , to the cultures decreased il-2 promoter activation by >80% .
O O O B-other_organic_compound O O O B-protein_molecule O O O O O O O O O B-protein_molecule O O O O O