We hypothesized that an intracellular vitamin D binding protein ( IDBP ) , present in both nuclear and cytoplasmic fractions of NWP cells , or another protein ( s ) may cause or contribute to the steroid hormone-resistant state in NWP by disruption of the receptor dimerization process and/or by interference of receptor complex binding to the consensus response elements present in the enhancer regions of steroid-responsive genes .
we hypothesized that an intracellular vitamin d binding protein ( idbp ) , present in both nuclear and cytoplasmic fractions of nwp cells , or another protein ( s ) may cause or contribute to the steroid hormone-resistant state in nwp by disruption of the receptor dimerization process and/or by interference of receptor complex binding to the consensus response elements present in the enhancer regions of steroid-responsive genes .
O O O O B-protein_molecule B-lipid I-lipid O O O B-protein_molecule O O O O O O O O O O B-cell_line I-cell_line O O O O O O O O O O O O O B-other_name I-other_name I-other_name O B-cell_line O O O O B-other_name I-other_name I-other_name O O O O B-protein_complex I-protein_complex O O O B-DNA_family_or_group I-DNA_family_or_group I-DNA_family_or_group O O O B-DNA_domain_or_region I-DNA_domain_or_region O B-DNA_family_or_group I-DNA_family_or_group O