To dissect the molecular basis for the unusual persistent expression of the IL-2 and IL-2-R alpha genes in these IARC 301 T cells , we have analyzed the interactions of constitutively expressed nuclear proteins with the 5' flanking regions of the IL-2 and IL-2-R alpha genes using both DNase I footprinting and gel retardation techniques .
to dissect the molecular basis for the unusual persistent expression of the il-2 and il-2-r alpha genes in these iarc 301 t cells , we have analyzed the interactions of constitutively expressed nuclear proteins with the 5' flanking regions of the il-2 and il-2-r alpha genes using both dnase i footprinting and gel retardation techniques .
O O O O O O O O O O O O O O O O O O O B-cell_line I-cell_line B-cell_type I-cell_type O O O O O O O B-protein_family_or_group I-protein_family_or_group I-protein_family_or_group I-protein_family_or_group O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O O O O O O O O O B-protein_molecule I-protein_molecule O O O O O O