Functional studies showed a 2 . 5-fold increase in promoter activity when this 19-bp binding site was deleted in the reporter constructs IL-1beta /CAT and IL-1beta /SV40 promoter /CAT .
functional studies showed a 2 . 5-fold increase in promoter activity when this 19-bp binding site was deleted in the reporter constructs il-1beta /cat and il-1beta /sv40 promoter /cat .
O O O O O O O O O B-other_name I-other_name O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O O O O B-DNA_family_or_group I-DNA_family_or_group B-protein_molecule B-protein_molecule O B-protein_molecule B-DNA_domain_or_region I-DNA_domain_or_region B-protein_molecule O