Qualitatively different effects were observed for the IL-1 -induced activation of stress-activated protein ( SAP ) kinases : permanent overexpression of IRAK did not affect the dose dependence but prolonged the kinetics of IL-1 -induced activation of SAP kinases , suggesting that this signaling branch may be regulated by distinct mechanisms .
qualitatively different effects were observed for the il-1 -induced activation of stress-activated protein ( sap ) kinases : permanent overexpression of irak did not affect the dose dependence but prolonged the kinetics of il-1 -induced activation of sap kinases , suggesting that this signaling branch may be regulated by distinct mechanisms .
O O O O O O O B-protein_molecule O O O B-protein_family_or_group I-protein_family_or_group I-protein_family_or_group I-protein_family_or_group I-protein_family_or_group I-protein_family_or_group O O O O B-protein_molecule O O O O O O O O O O O B-protein_molecule O O O B-protein_family_or_group I-protein_family_or_group O O O O O O O O O O O O O