However , suppression of IL-1R gene expression by IFN-gamma and IL-10 was associated with decreased tyrosine phosphorylation and nuclear translocation of the IL-4 / IL-13 -inducible transcription factor , Stat6 , suggesting a potential mechanism by which IFN-gamma and IL-10 may mediate their suppressive effects .
however , suppression of il-1r gene expression by ifn-gamma and il-10 was associated with decreased tyrosine phosphorylation and nuclear translocation of the il-4 / il-13 -inducible transcription factor , stat6 , suggesting a potential mechanism by which ifn-gamma and il-10 may mediate their suppressive effects .
O O O O B-protein_family_or_group O O O B-protein_molecule O B-protein_molecule O O O O B-amino_acid_monomer O O O O O O B-protein_molecule O B-protein_molecule O O O O B-protein_molecule O O O O O O O B-protein_molecule O B-protein_molecule O O O O O O