First , STAT4 was required for the IL-12 -dependent transactivation of an IRF-1 reporter construct , and second , STAT4 binding to the IRF-1 promoter was shown using EMSA .
first , stat4 was required for the il-12 -dependent transactivation of an irf-1 reporter construct , and second , stat4 binding to the irf-1 promoter was shown using emsa .
O O B-protein_molecule O O O O B-protein_molecule O O O O B-protein_molecule O O O O O O B-protein_molecule O O O B-protein_molecule O O O O B-other_name O