Recent studies from our laboratory have indicated that protein tyrosine phosphatase ( PTPase ) inhibitors can down-modulate the tumor necrosis factor ( TNF ) -mediated activation of the nuclear transcription factor NF-kappa B in ML-1a , a monocytic cell line ( Singh and Aggarwal , J . Biol . Chem . 1995 : 270 : 10631 ) .
recent studies from our laboratory have indicated that protein tyrosine phosphatase ( ptpase ) inhibitors can down-modulate the tumor necrosis factor ( tnf ) -mediated activation of the nuclear transcription factor nf-kappa b in ml-1a , a monocytic cell line ( singh and aggarwal , j . biol . chem . 1995 : 270 : 10631 ) .
O O O O O O O O B-protein_molecule I-protein_molecule I-protein_molecule O B-protein_molecule O O O O O B-protein_family_or_group I-protein_family_or_group I-protein_family_or_group O B-protein_family_or_group O O O O O B-protein_complex I-protein_complex I-protein_complex I-protein_complex I-protein_complex O B-cell_line O O B-cell_line I-cell_line I-cell_line O O O O O O O O O O O O O O O O O O