FK506 . FKBP12 drug-immunophilin complexes inhibited the interaction of NFAT with activated calcineurin much more effectively than they inhibited the interaction with inactive calcineurin , suggesting that part of the interaction with activated calcineurin involved the enzyme active site .
fk506 . fkbp12 drug-immunophilin complexes inhibited the interaction of nfat with activated calcineurin much more effectively than they inhibited the interaction with inactive calcineurin , suggesting that part of the interaction with activated calcineurin involved the enzyme active site .
B-other_organic_compound I-other_organic_compound I-other_organic_compound I-other_organic_compound I-other_organic_compound O O O O B-protein_family_or_group O O B-protein_molecule O O O O O O O O O O B-protein_molecule O O O O O O O O O B-protein_molecule O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O