Besides ligand-induced receptor heterodimerization and contacts of the two IL-4 receptor subunits alpha and gamma with Janus kinases JAK1 and JAK3 a prominent constitutive binding between JAK1 and signal transducer and activator of transcription STAT5 was detected .
besides ligand-induced receptor heterodimerization and contacts of the two il-4 receptor subunits alpha and gamma with janus kinases jak1 and jak3 a prominent constitutive binding between jak1 and signal transducer and activator of transcription stat5 was detected .
O O O O O O O O O O O O O O O O B-protein_family_or_group I-protein_family_or_group B-protein_molecule O B-protein_molecule O O B-other_name I-other_name O B-protein_molecule O B-protein_family_or_group I-protein_family_or_group I-protein_family_or_group I-protein_family_or_group I-protein_family_or_group I-protein_family_or_group B-protein_molecule O O O