By ablating the expression of the endogenous GATA-1 gene , we are in a position to introduce a variety of constructs that harbor subtle modifications in flanking or protein-coding sequences .
by ablating the expression of the endogenous gata-1 gene , we are in a position to introduce a variety of constructs that harbor subtle modifications in flanking or protein-coding sequences .
O O O O O O O B-protein_molecule O O O O O O O O O O O O O O O O O O O O B-DNA_domain_or_region I-DNA_domain_or_region O