We find that OCA-B binds DNA directly in the major groove between the two subdomains of the POU domain , requiring both an A at the fifth position of the octamer element and contact with the POU domain .
we find that oca-b binds dna directly in the major groove between the two subdomains of the pou domain , requiring both an a at the fifth position of the octamer element and contact with the pou domain .
O O O B-protein_molecule O O O O O B-DNA_substructure I-DNA_substructure O O O O O O B-DNA_domain_or_region I-DNA_domain_or_region O O O O B-nucleotide O O B-DNA_domain_or_region I-DNA_domain_or_region O O B-DNA_domain_or_region I-DNA_domain_or_region O O O O B-DNA_domain_or_region I-DNA_domain_or_region O