The recently discovered macrolide FK506 has been demonstrated to have potent immunosuppressive activity at concentrations 100-fold lower than cyclosporin A , a cyclic undecapeptide that is used to prevent rejection after transplantation of bone marrow and organs , such as kidney , heart , and liver .
the recently discovered macrolide fk506 has been demonstrated to have potent immunosuppressive activity at concentrations 100-fold lower than cyclosporin a , a cyclic undecapeptide that is used to prevent rejection after transplantation of bone marrow and organs , such as kidney , heart , and liver .
O O O B-other_organic_compound B-other_organic_compound O O O O O O B-other_name I-other_name O O O O O B-other_organic_compound I-other_organic_compound O O B-peptide I-peptide O O O O O O O O O B-tissue I-tissue O B-body_part O O O B-body_part O B-body_part O O B-body_part O