Functional analysis of the promoter by transient transfection assays indicated that synergistic action between an SP-1 -like element at -21/-12 , a GATA site at -59/-54 , and a novel regulatory element , CPRE ( - GGACTACAG - ) at -49/-41 , is essential for the promoter activity in murine erythroleukemia ( MEL ) cells .
functional analysis of the promoter by transient transfection assays indicated that synergistic action between an sp-1 -like element at -21/-12 , a gata site at -59/-54 , and a novel regulatory element , cpre ( - ggactacag - ) at -49/-41 , is essential for the promoter activity in murine erythroleukemia ( mel ) cells .
O O O O O O O O O O O O O O O B-protein_molecule O O O O O O B-DNA_domain_or_region I-DNA_domain_or_region O O O O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O B-DNA_domain_or_region O O B-DNA_domain_or_region O O O O O O O O O B-other_name I-other_name O B-cell_type I-cell_type I-cell_type I-cell_type I-cell_type I-cell_type O