These results suggest that homodimerization of the IL-4Ralpha chain is sufficient to transduce Jak1 -dependent intracellular signals that lead to IgE isotype switching .
these results suggest that homodimerization of the il-4ralpha chain is sufficient to transduce jak1 -dependent intracellular signals that lead to ige isotype switching .
O O O O O O O B-protein_subunit O O O O O B-protein_molecule O O O O O O B-protein_family_or_group I-protein_family_or_group O O