Phorbol ester treatment of monocytes inhibited IFN alpha-stimulated tyrosine phosphorylation of the transcription factors Stat1alpha , Stat2 , and Stat3 and of the tyrosine kinase Tyk2 but had no effect on IFN-gamma activation of Stat1alpha .
phorbol ester treatment of monocytes inhibited ifn alpha-stimulated tyrosine phosphorylation of the transcription factors stat1alpha , stat2 , and stat3 and of the tyrosine kinase tyk2 but had no effect on ifn-gamma activation of stat1alpha .
O O O O O O O O B-amino_acid_monomer O O O B-protein_family_or_group I-protein_family_or_group B-protein_molecule O B-protein_molecule O O B-protein_molecule O O O B-amino_acid_monomer O B-protein_molecule O O O O O B-protein_molecule O O B-protein_molecule O