Although peripheral blood T cells are largely unresponsive to these cytokines without prior activation , a small subset of CD8+ T cells ( CD8+CD18bright ) is strongly activated by the combination of IL-12 and IL-2 .
although peripheral blood t cells are largely unresponsive to these cytokines without prior activation , a small subset of cd8+ t cells ( cd8+cd18bright ) is strongly activated by the combination of il-12 and il-2 .
O O O B-cell_type I-cell_type O O O O O B-protein_family_or_group O O O O O O O O B-cell_type I-cell_type I-cell_type O B-cell_type O O O O O O O O B-protein_molecule O B-protein_molecule O