In response to activation of the Wnt signaling pathway , beta-catenin accumulates in the nucleus , where it cooperates with LEF/TCF ( for lymphoid enhancer factor and T-cell factor ) transcription factors to activate gene expression .
in response to activation of the wnt signaling pathway , beta-catenin accumulates in the nucleus , where it cooperates with lef/tcf ( for lymphoid enhancer factor and t-cell factor ) transcription factors to activate gene expression .
O O O O O O B-other_name I-other_name I-other_name O B-protein_molecule O O O B-cell_component O O O O O B-protein_family_or_group O O B-protein_family_or_group I-protein_family_or_group I-protein_family_or_group I-protein_family_or_group I-protein_family_or_group I-protein_family_or_group O B-protein_family_or_group I-protein_family_or_group O O B-other_name I-other_name O