OBJECTIVE : Many studies have suggested that there is a possible hormonal dysregulation of hypothalamic-pituitary-adrenal ( HPA ) axis and an increased cortisol clearance in patients with polycystic ovary syndrome ( PCOS ) .
objective : many studies have suggested that there is a possible hormonal dysregulation of hypothalamic-pituitary-adrenal ( hpa ) axis and an increased cortisol clearance in patients with polycystic ovary syndrome ( pcos ) .
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