To make clear the roles of RA and RAR alpha in the normal hematopoiesis , I have introduced the construct of human RAR alpha ( hRAR alpha ) into murine bone marrow cells with retroviral vector , and selected infected cells with drug resistant marker ( Neo ( r ) ) cultured on the stroma cell line ( PA6-neo ) , and analyzed the behavior of infected cells .
to make clear the roles of ra and rar alpha in the normal hematopoiesis , i have introduced the construct of human rar alpha ( hrar alpha ) into murine bone marrow cells with retroviral vector , and selected infected cells with drug resistant marker ( neo ( r ) ) cultured on the stroma cell line ( pa6-neo ) , and analyzed the behavior of infected cells .
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