These studies demonstrate that E2a- Pbx1 initiates programmed cell death of hematopoietic precursers by a mechanism that requires its chimeric transcriptional properties , but , unlike other nuclear oncoproteins , is independent of p53 .
these studies demonstrate that e2a- pbx1 initiates programmed cell death of hematopoietic precursers by a mechanism that requires its chimeric transcriptional properties , but , unlike other nuclear oncoproteins , is independent of p53 .
O O O O B-protein_molecule B-protein_molecule O B-other_name I-other_name I-other_name O B-cell_type I-cell_type O O O O O O O O O O O O O O B-protein_family_or_group I-protein_family_or_group O O O O B-protein_molecule O