Moreover , STAT5 was found to be the predominant STAT transcription factor used by IL-2 in human T cells , and specifically required a COOH-terminal region of IL-2R beta ( Ser386-Val525 ) , while STAT5 recruitment was not correlated to activation of IL-2R gamma or JAK3 .
moreover , stat5 was found to be the predominant stat transcription factor used by il-2 in human t cells , and specifically required a cooh-terminal region of il-2r beta ( ser386-val525 ) , while stat5 recruitment was not correlated to activation of il-2r gamma or jak3 .
O O B-protein_molecule O O O O O O B-protein_family_or_group I-protein_family_or_group I-protein_family_or_group O O B-protein_molecule O B-cell_type B-cell_type I-cell_type O O O O O B-protein_domain_or_region I-protein_domain_or_region O B-protein_molecule I-protein_molecule O B-protein_domain_or_region O O O B-protein_molecule O O O O O O O B-protein_molecule I-protein_molecule O B-protein_molecule O