The germline promoters ( Ko ) located upstream of the J region gene segments of the kappa locus also contain an octamer motif ( containing a single base pair mutation and referred to as the variant octamer ) which has been shown previously to bind Oct-1 and Oct-2 transcription factors in vitro .
the germline promoters ( ko ) located upstream of the j region gene segments of the kappa locus also contain an octamer motif ( containing a single base pair mutation and referred to as the variant octamer ) which has been shown previously to bind oct-1 and oct-2 transcription factors in vitro .
O B-DNA_family_or_group I-DNA_family_or_group O B-DNA_family_or_group O O O O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O O B-DNA_domain_or_region I-DNA_domain_or_region O O O B-DNA_domain_or_region I-DNA_domain_or_region O O O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O O O O O O O O O O O O O O O B-protein_molecule O B-protein_molecule B-protein_family_or_group I-protein_family_or_group O O O