To get further insights into the molecular mechanisms underlying the biological activity of Tat , we investigated the effect of endogenous and exogenous Tat protein on c-fos gene expression in T lymphoblastoid ( Jurkat ) and monocytic ( U937 ) cell lines , as well as in primary peripheral blood mononuclear cells ( PBMC ) .
to get further insights into the molecular mechanisms underlying the biological activity of tat , we investigated the effect of endogenous and exogenous tat protein on c-fos gene expression in t lymphoblastoid ( jurkat ) and monocytic ( u937 ) cell lines , as well as in primary peripheral blood mononuclear cells ( pbmc ) .
O O O O O O B-other_name I-other_name O O O O O B-protein_molecule O O O O O O O O O B-protein_molecule I-protein_molecule O O O O O O O O O O O O O O O O O O O O O O B-cell_type I-cell_type I-cell_type I-cell_type I-cell_type O B-cell_type O O