While ICN appeared primarily in the nucleus , DeltaE localized to cytoplasmic and nuclear membranes , suggesting that intranuclear localization is not essential for oncogenesis or transcriptional activation .
while icn appeared primarily in the nucleus , deltae localized to cytoplasmic and nuclear membranes , suggesting that intranuclear localization is not essential for oncogenesis or transcriptional activation .
O B-protein_domain_or_region O O O O B-cell_component O B-protein_molecule O O O O O O O O O O O O O O O O O B-other_name I-other_name O