Thus , through the differential use of the same promoter element , the composite kappa 3/CRE site , the TNF-alpha gene is regulated in a cell-type-specific manner in response to the same extracellular signal .
thus , through the differential use of the same promoter element , the composite kappa 3/cre site , the tnf-alpha gene is regulated in a cell-type-specific manner in response to the same extracellular signal .
O O O O O O O O O B-DNA_domain_or_region I-DNA_domain_or_region O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O O B-protein_molecule O O O O O B-other_name I-other_name O O O O O B-other_name I-other_name O