Mutagenesis studies , and the use of a reporter construct containing an enhancerless promoter , indicate that these transcriptional effects are due principally to the 22-bp sequence duplication and the NF kappa B site contained within it .
mutagenesis studies , and the use of a reporter construct containing an enhancerless promoter , indicate that these transcriptional effects are due principally to the 22-bp sequence duplication and the nf kappa b site contained within it .
O O O O O O O O O O O O O O O O O O O O O O O O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O O B-protein_molecule I-protein_molecule I-protein_molecule O O O O O