These results therefore demonstrate that the MHC class II gene silencing in somatic cell hybrids is due to an active suppression of one of the promoters of the CIITA gene , mediated by the epithelial cell fusion partner .
these results therefore demonstrate that the mhc class ii gene silencing in somatic cell hybrids is due to an active suppression of one of the promoters of the ciita gene , mediated by the epithelial cell fusion partner .
O O O O O O B-protein_family_or_group I-protein_family_or_group I-protein_family_or_group O O O B-cell_line I-cell_line I-cell_line O O O O O O O O O O B-DNA_domain_or_region O O B-protein_molecule O O O O O B-cell_type I-cell_type I-cell_type I-cell_type O