All cases tested ( 6/20 ) , including the case with t ( 11 ; 17 ) , failed to differentiate in vitro in response to all-trans retinoic acid ( ATRA ) , suggesting that these cases may account for some APLs that have not shown a clinical response to ATRA .
all cases tested ( 6/20 ) , including the case with t ( 11 ; 17 ) , failed to differentiate in vitro in response to all-trans retinoic acid ( atra ) , suggesting that these cases may account for some apls that have not shown a clinical response to atra .
O O O O O O O O O O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O O O O O O O O O B-other_organic_compound I-other_organic_compound I-other_organic_compound O B-other_organic_compound O O O O O O O O O O O O O O O O O O O B-other_organic_compound O