In vivo studies indicated that CD3 -induced HSI phosphorylation was dependent upon both the Src family tyrosine kinase Lck and the tyrosine phosphatase CD45 , did not require MEK1 kinase activity , and was regulated by protein kinase C activation .
in vivo studies indicated that cd3 -induced hsi phosphorylation was dependent upon both the src family tyrosine kinase lck and the tyrosine phosphatase cd45 , did not require mek1 kinase activity , and was regulated by protein kinase c activation .
O O O O O B-protein_molecule O B-protein_molecule O O O O O O B-protein_family_or_group I-protein_family_or_group I-protein_family_or_group I-protein_family_or_group B-protein_molecule O O B-protein_family_or_group I-protein_family_or_group B-protein_molecule O O O O B-protein_molecule O O O O O O O B-protein_molecule I-protein_molecule I-protein_molecule O O