We show that ATRA directly activates IRF-1 gene expression , followed by activation of IRF-2 and 2'-5' oligoadenylate synthetase ( OAS ) gene expression with slower kinetics .
we show that atra directly activates irf-1 gene expression , followed by activation of irf-2 and 2'-5' oligoadenylate synthetase ( oas ) gene expression with slower kinetics .
O O O B-other_organic_compound O O B-DNA_domain_or_region I-DNA_domain_or_region O O O O O O B-protein_molecule O B-protein_family_or_group I-protein_family_or_group I-protein_family_or_group O O O O O O O O O