However , there is a non-significant trend towards a down-regulation of hTR beta 1 mRNA levels in hyperthyroid patients .
however , there is a non-significant trend towards a down-regulation of htr beta 1 mrna levels in hyperthyroid patients .
O O O O O O O O O B-other_name O B-protein_molecule I-protein_molecule I-protein_molecule O O O B-multi_cell I-multi_cell O