Previous studies have implicated activation of both protein kinase C ( PKC ) and protein tyrosine kinases ( PTK ) in LPS -induced NF-kappaB activation and TNF-alpha production .
previous studies have implicated activation of both protein kinase c ( pkc ) and protein tyrosine kinases ( ptk ) in lps -induced nf-kappab activation and tnf-alpha production .
O O O O O O O B-protein_molecule I-protein_molecule I-protein_molecule O B-protein_molecule O O B-protein_family_or_group B-amino_acid_monomer O O B-protein_family_or_group O O B-lipid O B-protein_complex O O B-protein_molecule O O