The addition of anti-CD28 mAb to anti-CD3-stimulated cells markedly increased IL-2 production in both cell types , but levels of IL-2 in neonatal T cells remained clearly lower than those of adult T cells ( respective mean values : 385 +/- 109 pg/ml and 4494 +/- 1199 pg/ml ) .
the addition of anti-cd28 mab to anti-cd3-stimulated cells markedly increased il-2 production in both cell types , but levels of il-2 in neonatal t cells remained clearly lower than those of adult t cells ( respective mean values : 385 +/- 109 pg/ml and 4494 +/- 1199 pg/ml ) .
O O O B-protein_molecule I-protein_molecule O B-cell_line I-cell_line O O B-protein_molecule O O O O O O O O O B-protein_molecule O B-cell_type I-cell_type I-cell_type O O O O O O B-cell_type I-cell_type I-cell_type O O O O O O O O O O O O O O O O