Interestingly , apoptosis induced by NF-kappa B suppression , in contrast to that induced by TPEN ( N , N , N' , N'-tetrakis [ 2-pyridylmethyl ] ethylenediamine ) or soluble Fas ligand ( CD95 ) , was observed in the absence of active death effector proteases caspase-1 -like ( IL-1 converting enzyme ) , caspase-3 -like ( CPP32/Yama/apopain ) , and caspase-6 -like and without cleavage of caspase-3 substrates poly ( ADP -ribose ) polymerase and DNA fragmentation factor-45 .
interestingly , apoptosis induced by nf-kappa b suppression , in contrast to that induced by tpen ( n , n , n' , n'-tetrakis [ 2-pyridylmethyl ] ethylenediamine ) or soluble fas ligand ( cd95 ) , was observed in the absence of active death effector proteases caspase-1 -like ( il-1 converting enzyme ) , caspase-3 -like ( cpp32/yama/apopain ) , and caspase-6 -like and without cleavage of caspase-3 substrates poly ( adp -ribose ) polymerase and dna fragmentation factor-45 .
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