To study the regulatory mechanism of gp91phox gene expression in eosinophils , we transiently transfected eosinophil-committed HL-60-C15 cells with gp91phox promoter constructs , and identified a negative element from bp -267 to -246 of the gp91phox gene , the deletion of which caused an 83% increase in promoter activity .
to study the regulatory mechanism of gp91phox gene expression in eosinophils , we transiently transfected eosinophil-committed hl-60-c15 cells with gp91phox promoter constructs , and identified a negative element from bp -267 to -246 of the gp91phox gene , the deletion of which caused an 83% increase in promoter activity .
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