In order to investigate the nature of the A6H mAb costimulus at the transcriptional level we have examined induction of the transcription factors OCT-1 , AP-1 and NF-kappa B which are known to be transcriptional regulators of several cytokine and cytokine receptor genes , including the IL-2 and IL-2R genes .
in order to investigate the nature of the a6h mab costimulus at the transcriptional level we have examined induction of the transcription factors oct-1 , ap-1 and nf-kappa b which are known to be transcriptional regulators of several cytokine and cytokine receptor genes , including the il-2 and il-2r genes .
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