When used at differentiation-inducing concentrations , both topoisomerase inhibitors caused a great stimulation of AP-1 binding activity , with maximum value at hour 12 in etoposide -treated cells and at hour 48 in ICRF-193 -treated cells .
when used at differentiation-inducing concentrations , both topoisomerase inhibitors caused a great stimulation of ap-1 binding activity , with maximum value at hour 12 in etoposide -treated cells and at hour 48 in icrf-193 -treated cells .
O O O O O O O B-protein_family_or_group O O O O O O B-protein_molecule O O O O O O O O O O B-other_organic_compound O O O O O O O B-other_organic_compound O O O