A chimeric TCR gene , comprising an anti-hapten single-chain Ab variable fragment fused to the transmembrane and cytoplasmic regions of the human TCR zeta-chain , was used to determine whether the tetracycline-regulatable system could be used to regulate gene expression in T cells .
a chimeric tcr gene , comprising an anti-hapten single-chain ab variable fragment fused to the transmembrane and cytoplasmic regions of the human tcr zeta-chain , was used to determine whether the tetracycline-regulatable system could be used to regulate gene expression in t cells .
O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O O O B-protein_domain_or_region I-protein_domain_or_region I-protein_domain_or_region I-protein_domain_or_region I-protein_domain_or_region O O O B-protein_domain_or_region I-protein_domain_or_region I-protein_domain_or_region I-protein_domain_or_region O O B-protein_subunit I-protein_subunit I-protein_subunit O O O O O O O B-other_name I-other_name O O O O O B-other_name I-other_name O B-cell_type I-cell_type O