Our studies demonstrate for the first time that CD3 antigen-derived signals and CD2 antigen -derived signals are synergistic in inducing the emergence of transcription factors that bind to the NF-AT1 , AP-1 , and NF-kB sites located in the promoter/enhancer region of the IL-2 gene .
our studies demonstrate for the first time that cd3 antigen-derived signals and cd2 antigen -derived signals are synergistic in inducing the emergence of transcription factors that bind to the nf-at1 , ap-1 , and nf-kb sites located in the promoter/enhancer region of the il-2 gene .
O O O O O O O O B-protein_molecule O O O B-protein_family_or_group I-protein_family_or_group O O O O O O O O O B-protein_family_or_group I-protein_family_or_group O O O O O O O O O O O O O O B-DNA_domain_or_region I-DNA_domain_or_region O O B-protein_molecule O O