Our analyses of the induction of nuclear factor-kappaB ( NFkappaB ) in activated memory ( CD45RO+ ) and naive ( CD45RA+ ) T cell subsets from young and elderly donors has demonstrated that , regardless of donor age , memory T cells are not significantly altered in their responsiveness to TNF-alpha -mediated induction of NFkappaB .
our analyses of the induction of nuclear factor-kappab ( nfkappab ) in activated memory ( cd45ro+ ) and naive ( cd45ra+ ) t cell subsets from young and elderly donors has demonstrated that , regardless of donor age , memory t cells are not significantly altered in their responsiveness to tnf-alpha -mediated induction of nfkappab .
O O O O O O B-protein_complex I-protein_complex O B-protein_complex O O O O O O O O O O O O O O O O O O O O O O O O O O O O O B-cell_type I-cell_type I-cell_type O O O O O O O O B-protein_molecule O O O B-protein_complex O