In contrast , another inducible gene expression of monocyte chemotactic protein-1 ( a CC chemokine ) and the activation of the transcriptional factor ( FcRFgamma ) bound to the gamma response region were similarly or less abundantly induced by IFNgamma treatment in PMA -or RA -differentiated U937 cells , indicating that increased IP-10 mRNA induction was not due to the augmented ability of the cells to respond to the presence of IFNgamma .
in contrast , another inducible gene expression of monocyte chemotactic protein-1 ( a cc chemokine ) and the activation of the transcriptional factor ( fcrfgamma ) bound to the gamma response region were similarly or less abundantly induced by ifngamma treatment in pma -or ra -differentiated u937 cells , indicating that increased ip-10 mrna induction was not due to the augmented ability of the cells to respond to the presence of ifngamma .
O O O O O O O O B-protein_molecule I-protein_molecule I-protein_molecule O O B-protein_family_or_group I-protein_family_or_group O O O O O O B-protein_family_or_group I-protein_family_or_group O B-protein_molecule O O O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O O O O O O O B-protein_molecule O O B-other_organic_compound O B-other_organic_compound O B-cell_line I-cell_line O O O O B-protein_molecule O O O O O O O O O O O O O O O O O O B-protein_molecule O