Furthermore , compared with wild-type Id3 , an Id3 Asp5 mutant ( mimicking phosphorylation ) is unable to promote cell cycle S phase entry in transfected fibroblasts , whereas an Id3 Ala5 mutant ( ablating phosphorylation ) displays an activity significantly greater than that of wild-type Id3 protein .
furthermore , compared with wild-type id3 , an id3 asp5 mutant ( mimicking phosphorylation ) is unable to promote cell cycle s phase entry in transfected fibroblasts , whereas an id3 ala5 mutant ( ablating phosphorylation ) displays an activity significantly greater than that of wild-type id3 protein .
O O O O B-protein_molecule B-protein_molecule O O B-protein_molecule B-amino_acid_monomer O O O O O O O O O B-other_name I-other_name I-other_name I-other_name I-other_name O B-cell_line I-cell_line O O O B-protein_molecule B-amino_acid_monomer O O O O O O O O O O O O O B-protein_molecule B-protein_molecule O O