Oestradiol has mitogenic and regulatory effects on various organs and cells , mediated mainly by its nuclear receptor ( ER ) .
oestradiol has mitogenic and regulatory effects on various organs and cells , mediated mainly by its nuclear receptor ( er ) .
O O O O O O O O O O O O O O O O B-protein_family_or_group I-protein_family_or_group O B-protein_family_or_group O O