Using the 1G5 cell line harbouring the luciferase reporter gene under the control of the HIV-1 LTR , it was first found that culture protein filtrates ( CFP ) from M . tuberculosis or purified ManLAM could activate HIV-1 LTR -dependent gene expression unlike similarly prepared CFP extracts devoid of ManLAM .
using the 1g5 cell line harbouring the luciferase reporter gene under the control of the hiv-1 ltr , it was first found that culture protein filtrates ( cfp ) from m . tuberculosis or purified manlam could activate hiv-1 ltr -dependent gene expression unlike similarly prepared cfp extracts devoid of manlam .
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