Here we report that overexpression of Syk in the Lck -negative JCaM1 cells enabled the T cell antigen receptor /CD3 complex to induce a normal activation of the mitogen-activated protein kinase ( MAPK ) pathway and expression of a nuclear factor of activated T cells reporter construct .
here we report that overexpression of syk in the lck -negative jcam1 cells enabled the t cell antigen receptor /cd3 complex to induce a normal activation of the mitogen-activated protein kinase ( mapk ) pathway and expression of a nuclear factor of activated t cells reporter construct .
O O O O O O B-protein_molecule O O B-protein_molecule O O O O O B-protein_family_or_group I-protein_family_or_group I-protein_family_or_group I-protein_family_or_group O O O O O O O O O B-protein_family_or_group I-protein_family_or_group I-protein_family_or_group O B-protein_family_or_group O O O O O O B-protein_molecule I-protein_molecule I-protein_molecule I-protein_molecule B-cell_type I-cell_type O O O