When ligated to the proIL-1 beta cap site -proximal region ( located between -131 to +12 ) , both the proIL-1 beta and the simian virus 40 enhancer elements functioned more efficiently in monocytes than in HeLa cells , which are not normally competent for IL-1 beta expression .
when ligated to the proil-1 beta cap site -proximal region ( located between -131 to +12 ) , both the proil-1 beta and the simian virus 40 enhancer elements functioned more efficiently in monocytes than in hela cells , which are not normally competent for il-1 beta expression .
O O O O B-protein_molecule I-protein_molecule B-DNA_domain_or_region I-DNA_domain_or_region B-DNA_domain_or_region I-DNA_domain_or_region O O O O O O O O O O O O O O O O O O O O O O O B-cell_type O O B-cell_type I-cell_type O O O O O O O B-protein_molecule I-protein_molecule O O