Based upon these results we propose that alpha-interferon through its receptor initiates phosphatidic acid dependent signalling which in turn regulates the affinity of 47 kDa sterol regulatory element binding factor as well as LDL -receptor gene transcription in lymphocytes from CML patients .
based upon these results we propose that alpha-interferon through its receptor initiates phosphatidic acid dependent signalling which in turn regulates the affinity of 47 kda sterol regulatory element binding factor as well as ldl -receptor gene transcription in lymphocytes from cml patients .
O O O O O O O B-protein_molecule O O O O B-other_organic_compound I-other_organic_compound O O O O O O O O O B-protein_molecule I-protein_molecule I-protein_molecule I-protein_molecule I-protein_molecule I-protein_molecule I-protein_molecule O O O B-protein_molecule O O O O B-cell_type O B-other_name B-multi_cell O