Methylation studies indicated that the tal-15' GC-rich region behaves like a CpG island , hypomethylated in normal cells , and methylated de novo on transcriptionally inactive alleles in established cell lines .
methylation studies indicated that the tal-15' gc-rich region behaves like a cpg island , hypomethylated in normal cells , and methylated de novo on transcriptionally inactive alleles in established cell lines .
B-other_name I-other_name O O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O O O B-DNA_domain_or_region I-DNA_domain_or_region O O O B-cell_type I-cell_type O O O O O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O B-cell_line I-cell_line I-cell_line O