First , we showed that viral binding induced a number of immunoregulatory genes ( IL-1beta , A20 , NF-kappaB-p105/p50 , and IkappaBalpha ) in unactivated monocytes and that neutralizing Abs to the major HCMV glycoproteins , gB ( UL55 ) and gH ( UL75 ) , inhibited the induction of these genes .
first , we showed that viral binding induced a number of immunoregulatory genes ( il-1beta , a20 , nf-kappab-p105/p50 , and ikappabalpha ) in unactivated monocytes and that neutralizing abs to the major hcmv glycoproteins , gb ( ul55 ) and gh ( ul75 ) , inhibited the induction of these genes .
O O O O O O O O O O O B-cell_type I-cell_type O B-protein_molecule O B-protein_molecule O B-protein_complex O O B-protein_molecule O O O B-cell_type O O B-protein_family_or_group I-protein_family_or_group O O O B-virus O O B-protein_molecule O B-protein_molecule O O B-protein_molecule O B-protein_family_or_group O O O O O O O O O