Together , these results suggest that phosphorylation of I kappa B alpha , mediated through both the TNF-alpha -inducible and the PP-2A -opposing kinases , may serve to target I kappa B alpha for proteasome -mediated degradation .
together , these results suggest that phosphorylation of i kappa b alpha , mediated through both the tnf-alpha -inducible and the pp-2a -opposing kinases , may serve to target i kappa b alpha for proteasome -mediated degradation .
O O O O O O B-other_name O B-protein_molecule I-protein_molecule I-protein_molecule I-protein_molecule O O O O O B-protein_molecule O O O B-protein_family_or_group O O O O O O O B-protein_molecule I-protein_molecule I-protein_molecule I-protein_molecule O B-protein_complex O O O