To determine the contribution of the cytoplasmic domain of the IL-7 receptor alpha chain ( IL-7R alpha ) to activation of STAT proteins , transfectants of the murine pro-B cell line BAF3 were made that express chimeric receptors consisting of the extracellular domain of human granulocyte colony-stimulating factor receptor ( G-CSF-R ) and the transmembrane and intracellular domains of human IL-7R alpha .
to determine the contribution of the cytoplasmic domain of the il-7 receptor alpha chain ( il-7r alpha ) to activation of stat proteins , transfectants of the murine pro-b cell line baf3 were made that express chimeric receptors consisting of the extracellular domain of human granulocyte colony-stimulating factor receptor ( g-csf-r ) and the transmembrane and intracellular domains of human il-7r alpha .
O O O O O O B-protein_domain_or_region I-protein_domain_or_region O O B-protein_molecule O O O O B-protein_subunit I-protein_subunit O O O O B-protein_family_or_group I-protein_family_or_group O O O O B-cell_line I-cell_line I-cell_line I-cell_line I-cell_line O O O O B-protein_family_or_group I-protein_family_or_group O O O B-protein_domain_or_region I-protein_domain_or_region O B-protein_molecule I-protein_molecule I-protein_molecule I-protein_molecule I-protein_molecule O B-protein_molecule O O O O O O O O B-protein_subunit I-protein_subunit I-protein_subunit O