The aberrant activation of AP-1 by gp160 in CD4 positive T cells could result in up-regulation of cytokines containing AP-1 sites , e . g . interleukin-3 and granulocyte macrophage colony-stimulating factor , and concurrently lead to T cell unresponsiveness by inhibiting interleukin-2 secretion .
the aberrant activation of ap-1 by gp160 in cd4 positive t cells could result in up-regulation of cytokines containing ap-1 sites , e . g . interleukin-3 and granulocyte macrophage colony-stimulating factor , and concurrently lead to t cell unresponsiveness by inhibiting interleukin-2 secretion .
O O O O B-protein_molecule O B-protein_molecule O B-cell_type I-cell_type B-cell_type I-cell_type O O O O O B-protein_family_or_group O B-protein_molecule O O O O O O B-protein_molecule O B-protein_molecule I-protein_molecule I-protein_molecule I-protein_molecule O O O O O B-cell_type I-cell_type O O O B-protein_molecule O O