Taken together , these data demonstrate the existence of an HLA-DQ isotype-specific trans-acting factor , which functions independently of CIITA .
taken together , these data demonstrate the existence of an hla-dq isotype-specific trans-acting factor , which functions independently of ciita .
O O O O O O O O O O B-DNA_domain_or_region O O O O O O O O B-protein_molecule O