To investigate the mechanisms accounting for the impaired responses to gamma interferon , a model system for examining overall changes in protein tyrosine phosphorylation , activation of Jak1 and Jak2 and phosphorylation of Stat1 was developed in phorbol 12-myristate 13-acetate -differentiated U-937 cells .
to investigate the mechanisms accounting for the impaired responses to gamma interferon , a model system for examining overall changes in protein tyrosine phosphorylation , activation of jak1 and jak2 and phosphorylation of stat1 was developed in phorbol 12-myristate 13-acetate -differentiated u-937 cells .
O O O O O O O O O O B-protein_family_or_group I-protein_family_or_group O O O O O O O O O O B-amino_acid_monomer O O O O B-protein_molecule O B-protein_molecule O B-other_name O B-protein_family_or_group O O O B-other_organic_compound I-other_organic_compound I-other_organic_compound O O O O