In the culture system reported here , ( 1 ) the growth factor ( GF ) stimulus induces cord blood ( CB ) progenitor cells to proliferate and differentiate/mature exclusively along the erythroid lineage ; ( 2 ) this erythropoietic wave is characterized by less than 4% apoptotic cells ; ( 3 ) asymmetric divisions are virtually absent , ie , nonresponsive hematopoietic progenitors with no erythropoietic potential are forced into apoptosis ; ( 4 ) the system is cell division controlled ( cdc ) , ie , the number of divisions performed by each cell is monitored .
in the culture system reported here , ( 1 ) the growth factor ( gf ) stimulus induces cord blood ( cb ) progenitor cells to proliferate and differentiate/mature exclusively along the erythroid lineage ; ( 2 ) this erythropoietic wave is characterized by less than 4% apoptotic cells ; ( 3 ) asymmetric divisions are virtually absent , ie , nonresponsive hematopoietic progenitors with no erythropoietic potential are forced into apoptosis ; ( 4 ) the system is cell division controlled ( cdc ) , ie , the number of divisions performed by each cell is monitored .
O O O O O O O O O O O B-protein_family_or_group I-protein_family_or_group O B-protein_family_or_group O O O B-cell_type I-cell_type I-cell_type I-cell_type I-cell_type B-cell_type I-cell_type O O O O O O O B-cell_type I-cell_type O O O O O B-other_name I-other_name O O O O O O O O O O O O B-other_name I-other_name O O O O O O O B-cell_type I-cell_type O O O O O O O B-other_name O O O O O O O O O O O O O O O O O O O O O O O O O O O