IgE germline promoter reporter gene constructs carrying point mutations in the NF kappa B2 site were largely unresponsive to IL-4 stimulation in transient transfection experiments , while plasmids with similar mutations in the NF kappa B1 site responded to cytokine stimulation better than the wild-type promoter .
ige germline promoter reporter gene constructs carrying point mutations in the nf kappa b2 site were largely unresponsive to il-4 stimulation in transient transfection experiments , while plasmids with similar mutations in the nf kappa b1 site responded to cytokine stimulation better than the wild-type promoter .
B-protein_family_or_group O O O O O O B-other_name I-other_name O O B-protein_complex I-protein_complex I-protein_complex O O O O O B-protein_molecule O O O O O O O O O O O O O B-protein_complex I-protein_complex I-protein_complex O O O B-protein_family_or_group O O O O B-DNA_domain_or_region I-DNA_domain_or_region O