Aims of the study were to ( 1 ) assess the potential role of the expression of these genes in the maintenance and expansion of the neoplastic clones and ( 2 ) search for constitutional losses or rearrangements of one allele followed by a deletion of the second allele of the same genes in the leukemic cells .
aims of the study were to ( 1 ) assess the potential role of the expression of these genes in the maintenance and expansion of the neoplastic clones and ( 2 ) search for constitutional losses or rearrangements of one allele followed by a deletion of the second allele of the same genes in the leukemic cells .
O O O O O O O O O O O O O O O O O O O O O O O O O O B-cell_line I-cell_line O O O O O O O O O O O O B-DNA_domain_or_region O O O O O O O B-DNA_domain_or_region O O O O O O B-cell_type I-cell_type O