To define the mechanism of action of the Nef protein , the signal transduction pathways which may be affected in T cells by constitutive expression of the nef gene were examined .
to define the mechanism of action of the nef protein , the signal transduction pathways which may be affected in t cells by constitutive expression of the nef gene were examined .
O O O B-other_name I-other_name I-other_name O O B-protein_molecule O O O B-other_name I-other_name O O O O O O B-cell_type I-cell_type O O O O O O O O O O