Nevertheless , relatively high , pharmacological concentrations of RA ( 1 to 10 &mgr ; M ) overcome these differentiation blocks and induce terminal granulocytic differentiation of the MPRO promyelocytes while potentiating interleukin-3 ( IL-3 ) -induced commitment of EML cells to the granulocyte/monocyte lineage .
nevertheless , relatively high , pharmacological concentrations of ra ( 1 to 10 &mgr ; m ) overcome these differentiation blocks and induce terminal granulocytic differentiation of the mpro promyelocytes while potentiating interleukin-3 ( il-3 ) -induced commitment of eml cells to the granulocyte/monocyte lineage .
O O O O O B-other_name I-other_name O B-other_organic_compound O O O O O O O O O O O O O O B-other_name I-other_name I-other_name O O B-cell_type I-cell_type O O B-protein_molecule O B-protein_molecule O O O O B-cell_type I-cell_type O O O O O