Here we demonstrate that the c-myb proto-oncogene product , which is itself a DNA-binding protein and transcriptional transactivator , can interact synergistically with Z in activating the BMRF1 promoter in Jurkat cells ( a T-cell line ) or Raji cells ( an EBV -positive B-cell ) , whereas the c-myb gene product by itself has little effect .
here we demonstrate that the c-myb proto-oncogene product , which is itself a dna-binding protein and transcriptional transactivator , can interact synergistically with z in activating the bmrf1 promoter in jurkat cells ( a t-cell line ) or raji cells ( an ebv -positive b-cell ) , whereas the c-myb gene product by itself has little effect .
O O O O O B-DNA_domain_or_region O O O O O O O B-protein_family_or_group I-protein_family_or_group O B-protein_family_or_group I-protein_family_or_group O O O O O B-protein_molecule O O O B-DNA_domain_or_region I-DNA_domain_or_region O B-cell_line I-cell_line O O B-cell_line I-cell_line O O B-cell_line I-cell_line O O B-virus O O O O O O B-protein_molecule I-protein_molecule I-protein_molecule O O O O O O