Double-stimulation was used to demonstrate that , in a T lymphocytic cell line ( CEM ) , phorbol myristate acetate ( PMA ) rapidly induced NF-kappa B through a signaling pathway which did not involve reactive oxygen species ( ROS ) and was different from the activation triggered by either H2O2 or tumor necrosis factor-alpha ( TNF-alpha ) .
double-stimulation was used to demonstrate that , in a t lymphocytic cell line ( cem ) , phorbol myristate acetate ( pma ) rapidly induced nf-kappa b through a signaling pathway which did not involve reactive oxygen species ( ros ) and was different from the activation triggered by either h2o2 or tumor necrosis factor-alpha ( tnf-alpha ) .
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