Whereas T cells from young subjects stimulated with cross-linked anti-CD3epsilon mAb OKT3 plus PMA or with the lectin PHA plus PMA demonstrated considerable increases in c-Fos protein expression , the expression of c-Fos but not c-Jun was markedly reduced in stimulated T cells from certain elderly subjects .
whereas t cells from young subjects stimulated with cross-linked anti-cd3epsilon mab okt3 plus pma or with the lectin pha plus pma demonstrated considerable increases in c-fos protein expression , the expression of c-fos but not c-jun was markedly reduced in stimulated t cells from certain elderly subjects .
O B-cell_type I-cell_type O O O O O B-protein_molecule I-protein_molecule I-protein_molecule B-protein_molecule O B-other_organic_compound O O O B-protein_family_or_group B-protein_molecule O B-other_organic_compound O O O O B-protein_molecule O O O O O O B-protein_molecule O O B-protein_molecule O O O O O B-cell_type I-cell_type O O B-multi_cell I-multi_cell O