Targeted expression to specific tissues or cell lineages is a necessary feature of a gene therapy vector for many clinical applications , such as correction of hemoglobinopathies or thalassemias by transplantation of genetically modified hematopoietic stem cells .
targeted expression to specific tissues or cell lineages is a necessary feature of a gene therapy vector for many clinical applications , such as correction of hemoglobinopathies or thalassemias by transplantation of genetically modified hematopoietic stem cells .
B-other_name I-other_name O O O O O O O O O O O O B-virus I-virus I-virus O O B-other_name I-other_name O O O O O B-other_name O B-other_name O O O B-cell_type I-cell_type I-cell_type I-cell_type I-cell_type O