These mutations were introduced in the tax gene of the ACH functional molecular clone of HTLV-1 , and virus produced from the mutant ACH clones was examined for the ability to replicate and immortalize primary human lymphocytes .
these mutations were introduced in the tax gene of the ach functional molecular clone of htlv-1 , and virus produced from the mutant ach clones was examined for the ability to replicate and immortalize primary human lymphocytes .
O O O O O O B-DNA_domain_or_region I-DNA_domain_or_region O O B-DNA_molecule I-DNA_molecule I-DNA_molecule I-DNA_molecule O B-virus O O O O O O B-DNA_family_or_group I-DNA_family_or_group I-DNA_family_or_group O O O O O O O O O B-cell_type I-cell_type I-cell_type O