Thus , TAL1 activation in these patients may result from subtle alterations in cis-acting regulatory sequences ( affecting expression of a single TAL1 allele ) or changes in trans-acting factors that control TAL1 transcription ( affecting expression of both TAL1 alleles ) .
thus , tal1 activation in these patients may result from subtle alterations in cis-acting regulatory sequences ( affecting expression of a single tal1 allele ) or changes in trans-acting factors that control tal1 transcription ( affecting expression of both tal1 alleles ) .
O O B-protein_molecule O O O B-multi_cell O O O O O O B-DNA_family_or_group I-DNA_family_or_group I-DNA_family_or_group O O O O O B-DNA_domain_or_region B-protein_molecule O O O O O O O O O B-protein_molecule O O O O O O B-protein_molecule O O O