Phosphorylation of CREB occurred through a herbimycin A and Rp-cAMP- sensitive pathway , suggesting phosphorylation required antecedent activation of both protein tyrosine kinases ( PTK ) and protein kinase A ( PKA ) .
phosphorylation of creb occurred through a herbimycin a and rp-camp- sensitive pathway , suggesting phosphorylation required antecedent activation of both protein tyrosine kinases ( ptk ) and protein kinase a ( pka ) .
O O B-protein_family_or_group O O O O O O O O O O O O O O O O O B-protein_family_or_group B-amino_acid_monomer O O B-protein_family_or_group O O B-protein_molecule I-protein_molecule I-protein_molecule O B-protein_molecule O O