However , CD80 and CD86 also induce distinct signal transduction pathways including the tyrosine phosphorylation of CD28 and phospholipase Cgamma1 and the SH2 -dependent association of phosphoinositide 3-kinase with CD28 .
however , cd80 and cd86 also induce distinct signal transduction pathways including the tyrosine phosphorylation of cd28 and phospholipase cgamma1 and the sh2 -dependent association of phosphoinositide 3-kinase with cd28 .
O O B-protein_molecule O B-protein_molecule O O O B-other_name I-other_name I-other_name O O B-amino_acid_monomer O O B-protein_molecule O B-protein_molecule I-protein_molecule O O B-protein_molecule O O O B-protein_molecule I-protein_molecule O B-protein_molecule O