Our previous studies pertaining to macrophage response to LPS identified a novel DNA-binding domain located from -550 to -487 in the human TNF-alpha promoter that contains transcriptional activity , but lacks any known NF-kappaB -binding sites .
our previous studies pertaining to macrophage response to lps identified a novel dna-binding domain located from -550 to -487 in the human tnf-alpha promoter that contains transcriptional activity , but lacks any known nf-kappab -binding sites .
O O O O O O O O B-lipid O O O B-protein_domain_or_region I-protein_domain_or_region O O O O O O O B-DNA_domain_or_region B-protein_molecule O O O B-other_name I-other_name O O O O O B-protein_complex B-DNA_domain_or_region I-DNA_domain_or_region O