These findings demonstrate that cross-linking of MHC class II molecules transduced the negative signals through intracellular mechanisms different from those present in the cross-linking of surface IgM .
these findings demonstrate that cross-linking of mhc class ii molecules transduced the negative signals through intracellular mechanisms different from those present in the cross-linking of surface igm .
O O O O O O B-protein_family_or_group I-protein_family_or_group I-protein_family_or_group I-protein_family_or_group O O O O O O O O O O O O O O O O B-protein_family_or_group O