A novel T cell-specific negative regulatory element ( NRE ) composed of two protein-binding sites were mapped in the 5' flanking region of the IL-4 gene : -311CTCCCTTCT-303 ( NRE-I ) and -288CTTTTTGCTT-TGC-300 ( NRE-II ) .
a novel t cell-specific negative regulatory element ( nre ) composed of two protein-binding sites were mapped in the 5' flanking region of the il-4 gene : -311ctcccttct-303 ( nre-i ) and -288ctttttgctt-tgc-300 ( nre-ii ) .
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