Moreover , replacement of the DQB X2-box with the DRA X2-box markedly diminished the activity of the DQB promoter in the mutant cell .
moreover , replacement of the dqb x2-box with the dra x2-box markedly diminished the activity of the dqb promoter in the mutant cell .
O O O O O B-DNA_domain_or_region I-DNA_domain_or_region O O B-DNA_domain_or_region I-DNA_domain_or_region O O O O O O B-DNA_domain_or_region I-DNA_domain_or_region O O B-cell_line I-cell_line O