Gene targeting studies have demonstrated crucial roles for the transcription factors Ikaros and Aiolos in regulating multiple stages of B and T cell development .
gene targeting studies have demonstrated crucial roles for the transcription factors ikaros and aiolos in regulating multiple stages of b and t cell development .
O O O O O O O O O B-protein_family_or_group I-protein_family_or_group B-protein_molecule O B-protein_molecule O O O O O O O O O O O