Thus , these results show that age-related impairments in the activation of AP-1 and NF-AT are closely associated with decreased expression of IL-2 and further suggest that aberrancies in the signaling pathways important for the induction of transcriptionally active c-Fos/c-Jun AP-1 may contribute to the impaired activation of NF-AT .
thus , these results show that age-related impairments in the activation of ap-1 and nf-at are closely associated with decreased expression of il-2 and further suggest that aberrancies in the signaling pathways important for the induction of transcriptionally active c-fos/c-jun ap-1 may contribute to the impaired activation of nf-at .
O O O O O O B-other_name I-other_name O O O O B-protein_molecule O B-protein_molecule O O O O O O O B-protein_molecule O O O O O O O B-other_name I-other_name O O O O O O O B-protein_complex B-protein_molecule O O O O O O O B-protein_complex O