Autoreactive B-cells are eliminated by anti-IgM crosslinking after encountering self-antigens , but precise mechanisms leading to B-cell apoptosis are still not well understood .
autoreactive b-cells are eliminated by anti-igm crosslinking after encountering self-antigens , but precise mechanisms leading to b-cell apoptosis are still not well understood .
B-cell_type I-cell_type O O O B-protein_family_or_group O O O B-protein_family_or_group O O O O O O B-cell_type O O O O O O O