Instead , we propose that ligation of a distinct inhibitory receptor leads to the recruitment of SHP1 via its SH2 domains , activation of SHP1 and subsequently inhibition of TCR signals if the inhibitory receptor is juxtaposed to the TCR .
instead , we propose that ligation of a distinct inhibitory receptor leads to the recruitment of shp1 via its sh2 domains , activation of shp1 and subsequently inhibition of tcr signals if the inhibitory receptor is juxtaposed to the tcr .
O O O O O O O O O B-protein_family_or_group I-protein_family_or_group O O O O O B-protein_molecule O O B-protein_domain_or_region I-protein_domain_or_region O O O B-protein_molecule O O O O B-protein_family_or_group O O O B-protein_family_or_group I-protein_family_or_group O O O O B-protein_family_or_group O