Once activated , the GR , can mediate his effects through direct binding on the DNA or via protein/protein interactions with transcription factors .
once activated , the gr , can mediate his effects through direct binding on the dna or via protein/protein interactions with transcription factors .
O O O O B-protein_family_or_group O O O O O O O O O O O O O B-other_name I-other_name O B-protein_family_or_group I-protein_family_or_group O