In fibroblasts , an important effector for the Ras oncogene is Phosphatidylinositol 3-kinase ( PtdIns 3-kinase ) .
in fibroblasts , an important effector for the ras oncogene is phosphatidylinositol 3-kinase ( ptdins 3-kinase ) .
O B-cell_type O O O O O O B-DNA_domain_or_region I-DNA_domain_or_region O B-protein_molecule I-protein_molecule O B-protein_molecule I-protein_molecule O O