We have isolated TFIIH from cells derived from a patient ( XP11BE ) who carries this frameshift mutation ( TFIIHmut ) and from the mother of this patient ( TFIIHwt ) to determine the biochemical consequences of the mutation .
we have isolated tfiih from cells derived from a patient ( xp11be ) who carries this frameshift mutation ( tfiihmut ) and from the mother of this patient ( tfiihwt ) to determine the biochemical consequences of the mutation .
O O O B-protein_molecule O O O O O B-multi_cell O B-multi_cell O O O O B-other_name I-other_name O B-protein_molecule O O O O B-multi_cell O O B-multi_cell O B-protein_molecule O O O O B-other_name I-other_name O O O O