Tumor necrosis factor receptor-1 ( TNFR-1 ) and CD95 ( also called Fas or APO-1 ) are cytokine receptors that engage the apoptosis pathway through a region of intracellular homology , designated the " death domain . " Another death domain -containing member of the TNFR family , death receptor 3 ( DR3 ) , was identified and was shown to induce both apoptosis and activation of nuclear factor kappaB .
tumor necrosis factor receptor-1 ( tnfr-1 ) and cd95 ( also called fas or apo-1 ) are cytokine receptors that engage the apoptosis pathway through a region of intracellular homology , designated the " death domain . " another death domain -containing member of the tnfr family , death receptor 3 ( dr3 ) , was identified and was shown to induce both apoptosis and activation of nuclear factor kappab .
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