We first demonstrate , in human and mouse intraspecies hybrids , the coordinate suppression of MHC class II , Ii ( invariant chain ) and HLA-DM gene transcription , and the release of the silencing by the addition of interferon gamma .
we first demonstrate , in human and mouse intraspecies hybrids , the coordinate suppression of mhc class ii , ii ( invariant chain ) and hla-dm gene transcription , and the release of the silencing by the addition of interferon gamma .
O O O O O B-cell_line I-cell_line I-cell_line I-cell_line I-cell_line O O O O O B-protein_family_or_group I-protein_family_or_group I-protein_family_or_group O B-protein_domain_or_region O B-protein_domain_or_region I-protein_domain_or_region O O B-DNA_domain_or_region I-DNA_domain_or_region O O O O O O O O O O O O B-protein_molecule I-protein_molecule O