The demonstration that NF-kappa B can regulate I kappa B alpha /MAD-3 gene transcription in other cell types suggested that the rapid increase in steady-state I kappa B alpha /MAD-3 mRNA levels we observed within 30 min of monocyte adherence would result from NF-kappa B -dependent transcriptional stimulation of the I kappa B alpha /MAD-3 gene .
the demonstration that nf-kappa b can regulate i kappa b alpha /mad-3 gene transcription in other cell types suggested that the rapid increase in steady-state i kappa b alpha /mad-3 mrna levels we observed within 30 min of monocyte adherence would result from nf-kappa b -dependent transcriptional stimulation of the i kappa b alpha /mad-3 gene .
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