In both cases , induction of TNF-alpha gene transcription can be blocked by the immunosuppressants cyclosporin A and FK506 , which suggested a role for the NFAT family of proteins in the regulation of the gene in B cells .
in both cases , induction of tnf-alpha gene transcription can be blocked by the immunosuppressants cyclosporin a and fk506 , which suggested a role for the nfat family of proteins in the regulation of the gene in b cells .
O O O O O O B-DNA_domain_or_region I-DNA_domain_or_region O O O O O O B-other_organic_compound B-other_organic_compound I-other_organic_compound O B-other_organic_compound O O O O O O O B-protein_family_or_group I-protein_family_or_group O O O O O O O O O B-cell_type I-cell_type O