Whereas mutations in the GATA-3 site abolished antigen- or cAMP- stimulated IL-5 promoter activation in Th2 cells , ectopic expression of GATA-3 in Th1 cells or in a non-lymphoid , non- IL-5 -producing cell line activated the IL-5 promoter .
whereas mutations in the gata-3 site abolished antigen- or camp- stimulated il-5 promoter activation in th2 cells , ectopic expression of gata-3 in th1 cells or in a non-lymphoid , non- il-5 -producing cell line activated the il-5 promoter .
O O O O B-protein_molecule O O O O O O O O O O O O O O O O B-protein_molecule O B-cell_type I-cell_type O O O B-cell_line I-cell_line I-cell_line B-protein_molecule O O O O O B-protein_molecule O O