When the cells were exposed to increasing concentrations of tetracyclines , surface expression of the chimeric receptor was suppressed in a dose-dependent manner , and this suppression was sufficient to result in complete loss of responsiveness to the targeted Ag .
when the cells were exposed to increasing concentrations of tetracyclines , surface expression of the chimeric receptor was suppressed in a dose-dependent manner , and this suppression was sufficient to result in complete loss of responsiveness to the targeted ag .
O O O O O O O O O B-other_organic_compound O B-other_name I-other_name O O B-protein_molecule I-protein_molecule O O O O B-other_name I-other_name O O O O O O O O O O O O O O O B-protein_molecule I-protein_molecule O