To model effective versus ineffective CD3 -mediated stimulation in peripheral T cells , we used two anti-CD3 mAbs that differ in their ability to stimulate purified T cells : OKT3 , which causes early second messenger generation but is unable to activate T cells without a second signal , and 64 . 1 , which stimulates T cell proliferation on its own .
to model effective versus ineffective cd3 -mediated stimulation in peripheral t cells , we used two anti-cd3 mabs that differ in their ability to stimulate purified t cells : okt3 , which causes early second messenger generation but is unable to activate t cells without a second signal , and 64 . 1 , which stimulates t cell proliferation on its own .
O O O O O B-protein_molecule O O O B-cell_type I-cell_type I-cell_type O O O O B-protein_family_or_group I-protein_family_or_group O O O O O O O B-cell_type I-cell_type I-cell_type O B-protein_molecule O O O B-other_name I-other_name I-other_name I-other_name O O O O O B-cell_type I-cell_type O O O O O O B-protein_molecule I-protein_molecule I-protein_molecule O O O B-cell_type I-cell_type O O O O O