In the case of IgE class switching , IL-4 activates the IgE germline promoter by inducing the interaction of the transcription factor STAT6 ( IL-4STAT ) with a responsive DNA element in the proximal region of the promoter .
in the case of ige class switching , il-4 activates the ige germline promoter by inducing the interaction of the transcription factor stat6 ( il-4stat ) with a responsive dna element in the proximal region of the promoter .
O O O O B-protein_family_or_group O O O B-protein_molecule O O B-protein_family_or_group O O O O O O O O B-protein_family_or_group I-protein_family_or_group B-protein_molecule O B-protein_molecule O O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O O B-DNA_domain_or_region I-DNA_domain_or_region O O B-DNA_domain_or_region O