Additionally , Nef inhibits the induction of HIV-1- and interleukin 2- directed gene expression , and the effect on HIV-1 transcription depends on an intact NF-kappa B -binding site .
additionally , nef inhibits the induction of hiv-1- and interleukin 2- directed gene expression , and the effect on hiv-1 transcription depends on an intact nf-kappa b -binding site .
O O B-protein_molecule O O O O O O O O O O O O O O O O B-virus O O O O O B-protein_molecule I-protein_molecule O O O