Estrogens affect vascular tone indirectly by modulating release of endothelium-derived vasoactive factors and directly by modulating intracellular calcium in vascular smooth muscle cells .
estrogens affect vascular tone indirectly by modulating release of endothelium-derived vasoactive factors and directly by modulating intracellular calcium in vascular smooth muscle cells .
B-lipid O B-other_name I-other_name O O O O O B-protein_family_or_group I-protein_family_or_group I-protein_family_or_group O O O O B-atom I-atom O B-cell_type I-cell_type I-cell_type I-cell_type O