In contrast to the purely enhancer-dependent effect of cytokines such as TNF on the activity of the HIV regulatory region ( LTR ) , we observed that okadaic acid ( OKA ) activates HIV transcription through both the enhancer , responding to the factor NF-kappa B , and the promoter domain of the LTR .
in contrast to the purely enhancer-dependent effect of cytokines such as tnf on the activity of the hiv regulatory region ( ltr ) , we observed that okadaic acid ( oka ) activates hiv transcription through both the enhancer , responding to the factor nf-kappa b , and the promoter domain of the ltr .
O O O O O B-other_name I-other_name O B-protein_family_or_group O O B-protein_family_or_group O O O O O B-virus O O O B-DNA_domain_or_region O O O O O B-other_organic_compound I-other_organic_compound O B-other_organic_compound O O B-virus O O O O O O O O O O B-protein_molecule I-protein_molecule O O O B-DNA_domain_or_region I-DNA_domain_or_region O O B-DNA_domain_or_region O