Furthermore , point mutations that abolish binding of NF-E1 result in a 70% decrease in the transcriptional activity of a megakaryocytic-specific promoter .
furthermore , point mutations that abolish binding of nf-e1 result in a 70% decrease in the transcriptional activity of a megakaryocytic-specific promoter .
O O O O O O O O B-protein_molecule O O O O O O O B-other_name I-other_name O O B-DNA_domain_or_region I-DNA_domain_or_region O