Taken together with the detection of CBF beta - MYH11 transcripts in the absence of apparent chromosome 16 abnormalities by classical banding techniques , these data show that additional screening by either RT-PCR or FISH should be performed in all AML M4 , regardless of morphologic features , to allow accurate evaluation of the prognostic importance of this fusion transcript .
taken together with the detection of cbf beta - myh11 transcripts in the absence of apparent chromosome 16 abnormalities by classical banding techniques , these data show that additional screening by either rt-pcr or fish should be performed in all aml m4 , regardless of morphologic features , to allow accurate evaluation of the prognostic importance of this fusion transcript .
O O O O O O B-DNA_domain_or_region I-DNA_domain_or_region O B-DNA_domain_or_region O O O O O O B-DNA_molecule I-DNA_molecule O O O O O O O O O O O O O O B-other_name O B-other_name O O O O O B-other_name I-other_name O O O O O O O O O O O O O O O O B-RNA_family_or_group I-RNA_family_or_group O