Using synthetic ligands to retinoic acid receptors ( RARs ) and retinoid X receptors ( RXRs ) that selectively bind and activate RAR-RXR or RXR-RXR dimers , respectively , we dissected the involvement of the two retinoid response pathways in the regulation of normal myeloid and erythroid progenitor cell growth .
using synthetic ligands to retinoic acid receptors ( rars ) and retinoid x receptors ( rxrs ) that selectively bind and activate rar-rxr or rxr-rxr dimers , respectively , we dissected the involvement of the two retinoid response pathways in the regulation of normal myeloid and erythroid progenitor cell growth .
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