Subsequent analysis of the human ICAM-1 promoter has revealed that both 12-O-tetradecanoylphorbol 13-acetate ( TPA ) and tumour necrosis factor-alpha ( TNF-alpha ) upregulate ICAM-1 expression through the presence of a nuclear factor ( NF-kappa B ) target sequence ( TGGAAATTCC ) .
subsequent analysis of the human icam-1 promoter has revealed that both 12-o-tetradecanoylphorbol 13-acetate ( tpa ) and tumour necrosis factor-alpha ( tnf-alpha ) upregulate icam-1 expression through the presence of a nuclear factor ( nf-kappa b ) target sequence ( tggaaattcc ) .
O O O O B-DNA_domain_or_region B-protein_molecule O O O O O B-other_organic_compound I-other_organic_compound O B-other_organic_compound O O B-protein_molecule I-protein_molecule I-protein_molecule O B-protein_molecule O O B-protein_molecule O O O O O O B-protein_family_or_group I-protein_family_or_group O B-protein_complex I-protein_complex O O O O B-polynucleotide O O