Cyclosporin A ( CsA ) may achieve its immunosuppressive effects by inhibiting the calcium- and calmodulin-dependent phosphatase calcineurin which is required for activation of target genes by members of the NFAT ( nuclear factor of activated T cells ) transcription factor family .
cyclosporin a ( csa ) may achieve its immunosuppressive effects by inhibiting the calcium- and calmodulin-dependent phosphatase calcineurin which is required for activation of target genes by members of the nfat ( nuclear factor of activated t cells ) transcription factor family .
B-other_organic_compound I-other_organic_compound O B-other_organic_compound O O O O B-other_name I-other_name O O O B-protein_family_or_group I-protein_family_or_group I-protein_family_or_group I-protein_family_or_group B-protein_molecule O O O O O O B-DNA_family_or_group I-DNA_family_or_group O O O O B-protein_family_or_group I-protein_family_or_group B-protein_family_or_group I-protein_family_or_group I-protein_family_or_group I-protein_family_or_group I-protein_family_or_group I-protein_family_or_group O O O O O