Upon ligand binding and cytokine receptor dimerization , Stat proteins are phosphorylated on tyrosine residues by Jak kinases .
upon ligand binding and cytokine receptor dimerization , stat proteins are phosphorylated on tyrosine residues by jak kinases .
O O O O B-protein_family_or_group I-protein_family_or_group O O B-protein_family_or_group I-protein_family_or_group O O O B-amino_acid_monomer I-amino_acid_monomer O B-protein_family_or_group I-protein_family_or_group O