Some antioxidants , including butylated hydroxyanisole ( BHA ) , tetrahydropapaveroline ( THP ) , nordihydroguiauretic acid , and 10 , 11-dihydroxyaporphine ( DHA ) , were found to be potent inhibitors of the production of tumor necrosis factor ( TNF ) -alpha , IL-1 beta , and IL-6 by human peripheral blood mononuclear cells ( PBMC ) stimulated by lipopolysaccharide ( LPS ) ( IC50s in the low micromolar range ) .
some antioxidants , including butylated hydroxyanisole ( bha ) , tetrahydropapaveroline ( thp ) , nordihydroguiauretic acid , and 10 , 11-dihydroxyaporphine ( dha ) , were found to be potent inhibitors of the production of tumor necrosis factor ( tnf ) -alpha , il-1 beta , and il-6 by human peripheral blood mononuclear cells ( pbmc ) stimulated by lipopolysaccharide ( lps ) ( ic50s in the low micromolar range ) .
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