However , we show that mutant forms of E1A that no longer bind p300/CBP can still interact directly with Stat1 ( via E1A N-terminal and Stat1 C-terminal residues ) and block IFNgamma-driven , Stat1 -dependent gene activation and consequent function during early-phase infection in the natural host cell .
however , we show that mutant forms of e1a that no longer bind p300/cbp can still interact directly with stat1 ( via e1a n-terminal and stat1 c-terminal residues ) and block ifngamma-driven , stat1 -dependent gene activation and consequent function during early-phase infection in the natural host cell .
O O O O O O O O B-protein_molecule O O O O B-protein_molecule O O O O O B-protein_molecule O O O O O O O O O O O B-other_name I-other_name B-protein_molecule O O O O O O O B-other_name I-other_name O O B-cell_type I-cell_type I-cell_type O