All mutants , including one extensively mutagenized strain entirely missing the NF-kappaB and four Spl binding elements , replicated with wild-type kinetics and to a wild-type level in peripheral blood mononuclear cell cultures in 50 to 100% of the experiments .
all mutants , including one extensively mutagenized strain entirely missing the nf-kappab and four spl binding elements , replicated with wild-type kinetics and to a wild-type level in peripheral blood mononuclear cell cultures in 50 to 100% of the experiments .
O O O O O O B-virus I-virus O O O O O O O O O O O O B-other_name I-other_name O O O O O O B-cell_line I-cell_line I-cell_line I-cell_line I-cell_line O O O O O O O O