The median dissociation constant ( Kd ) was similar in all three groups of patients and in healthy women ( mean +/- S . D . ( range ) : PHP , 1 . 2 +/- 1 . 0 ( 0 . 2-4 ) x 10 ( -10 ) M ; SH , 0 . 6 +/- 0 . 4 ( 0 . 2-1 . 2 ) x 10 ( -10 ) M ; RT , 1 . 1 +/- 0 . 5 ( 0 . 4-1 . 9 ) x 10 ( -10 ) M ; controls , 1 . 0 +/- 0 . 6 ( 0 . 3-2 . 6 ) x 10 ( -10 ) M ) . However , the maximal binding capacity ( Nmax ) was significantly enhanced in PHP ( 3 . 9 +/- 1 . 9 ( 1 . 3-7 . 6 ) fmol/10 ( 7 ) cells vs . 2 . 3 +/- 0 . 9 ( 1 . 1-4 . 4 ) fmol/10 ( 7 ) cells in controls ; P = 0 . 0006 ) and decreased in SH ( 0 . 8 +/- 0 . 5 ( 0 . 2-1 . 6 ) fmol/10 ( 7 ) cells vs . 2 . 3 +/- 0 . 9 ( 1 . 1-4 . 4 ) fmol/10 ( 7 ) cells in controls ; P = 0 . 0001 ) , whereas no changes were seen in RT ( 2 . 3 +/- 0 . 7 ( 1 . 2-3 . 3 ) fmol/10 ( 7 ) cells vs . 2 . 3 +/- 0 . 9 ( 1 . 1-4 . 4 ) fmol/10 ( 7 ) cells in controls ) .
the median dissociation constant ( kd ) was similar in all three groups of patients and in healthy women ( mean +/- s . d . ( range ) : php , 1 . 2 +/- 1 . 0 ( 0 . 2-4 ) x 10 ( -10 ) m ; sh , 0 . 6 +/- 0 . 4 ( 0 . 2-1 . 2 ) x 10 ( -10 ) m ; rt , 1 . 1 +/- 0 . 5 ( 0 . 4-1 . 9 ) x 10 ( -10 ) m ; controls , 1 . 0 +/- 0 . 6 ( 0 . 3-2 . 6 ) x 10 ( -10 ) m ) . however , the maximal binding capacity ( nmax ) was significantly enhanced in php ( 3 . 9 +/- 1 . 9 ( 1 . 3-7 . 6 ) fmol/10 ( 7 ) cells vs . 2 . 3 +/- 0 . 9 ( 1 . 1-4 . 4 ) fmol/10 ( 7 ) cells in controls ; p = 0 . 0006 ) and decreased in sh ( 0 . 8 +/- 0 . 5 ( 0 . 2-1 . 6 ) fmol/10 ( 7 ) cells vs . 2 . 3 +/- 0 . 9 ( 1 . 1-4 . 4 ) fmol/10 ( 7 ) cells in controls ; p = 0 . 0001 ) , whereas no changes were seen in rt ( 2 . 3 +/- 0 . 7 ( 1 . 2-3 . 3 ) fmol/10 ( 7 ) cells vs . 2 . 3 +/- 0 . 9 ( 1 . 1-4 . 4 ) fmol/10 ( 7 ) cells in controls ) .
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