We show that ligand-induced homodimerization of chimeric surface receptors consisting of the extracellular and transmembrane domains of the erythropoietin receptor and of the intracellular domain of IL-4Ralpha induces Janus kinase 1 ( Jak1 ) activation , STAT6 activation , and Cepsilon germline transcripts in human B cell line BJAB .
we show that ligand-induced homodimerization of chimeric surface receptors consisting of the extracellular and transmembrane domains of the erythropoietin receptor and of the intracellular domain of il-4ralpha induces janus kinase 1 ( jak1 ) activation , stat6 activation , and cepsilon germline transcripts in human b cell line bjab .
O O O O O O B-protein_family_or_group I-protein_family_or_group I-protein_family_or_group O O O O O O O O O B-protein_family_or_group I-protein_family_or_group O O O B-protein_domain_or_region I-protein_domain_or_region O B-protein_subunit O B-protein_molecule I-protein_molecule I-protein_molecule O B-protein_molecule O O O B-protein_molecule O O O B-RNA_family_or_group I-RNA_family_or_group I-RNA_family_or_group O B-cell_line I-cell_line I-cell_line I-cell_line I-cell_line O