In functional studies , interferon-gamma -stimulated PIEC clones transfected with this mutated CIITA construct failed to stimulate purified human CD4+ T lymphocytes .
in functional studies , interferon-gamma -stimulated piec clones transfected with this mutated ciita construct failed to stimulate purified human cd4+ t lymphocytes .
O O O O B-protein_molecule O B-cell_line I-cell_line O O O B-protein_molecule B-protein_molecule O O O O O B-cell_type I-cell_type I-cell_type I-cell_type O