The addition of TGF-beta to human B lymphocyte cultures stimulated with Staphylococcus aureus Cowan strain I and IL-2 completely inhibited B cell Ig secretion ( greater than 90% ) and decreased B cell surface IgM , IgD , kappa L chain , and lambda L chain expression .
the addition of tgf-beta to human b lymphocyte cultures stimulated with staphylococcus aureus cowan strain i and il-2 completely inhibited b cell ig secretion ( greater than 90% ) and decreased b cell surface igm , igd , kappa l chain , and lambda l chain expression .
O O O B-protein_molecule O B-cell_line I-cell_line I-cell_line I-cell_line O O B-mono_cell I-mono_cell I-mono_cell I-mono_cell I-mono_cell O B-protein_molecule O O B-cell_type I-cell_type B-protein_family_or_group O O O O O O O O B-cell_type I-cell_type O O O O O O O O O O O O O O O