The decreased expression of immunoglobulin genes indicates that the ras oncogene blocks terminal differentiation to plasma cells , possibly by inhibiting the activity of lymphocyte-specific transcription factors .
the decreased expression of immunoglobulin genes indicates that the ras oncogene blocks terminal differentiation to plasma cells , possibly by inhibiting the activity of lymphocyte-specific transcription factors .
O O O O B-DNA_family_or_group I-DNA_family_or_group O O O B-DNA_domain_or_region I-DNA_domain_or_region O O O O B-cell_type I-cell_type O O O O O O O B-protein_family_or_group I-protein_family_or_group I-protein_family_or_group O