Consistent with a role for bcl-xL in mediating GATA-1 -induced erythroid cell survival , in vitro-differentiated bcl-xL -/- embryonic stem cells fail to generate viable mature definitive erythroid cells , a phenotype resembling that of GATA-1 gene disruption .
consistent with a role for bcl-xl in mediating gata-1 -induced erythroid cell survival , in vitro-differentiated bcl-xl -/- embryonic stem cells fail to generate viable mature definitive erythroid cells , a phenotype resembling that of gata-1 gene disruption .
O O O O O B-protein_molecule O O B-protein_molecule O B-other_name B-other_name I-other_name O O B-cell_line B-protein_molecule O O O O O O O O O O B-cell_type I-cell_type O O O O O O B-DNA_domain_or_region I-DNA_domain_or_region O O