When restimulated , however , anergic T cells fail to up-regulate transcription of the IL-2 gene and in consequence do not produce IL-2 .
when restimulated , however , anergic t cells fail to up-regulate transcription of the il-2 gene and in consequence do not produce il-2 .
O O O O O B-cell_type I-cell_type I-cell_type O O O O O O B-DNA_domain_or_region I-DNA_domain_or_region O O O O O O B-protein_molecule O