Full activation of the MAP kinases that phosphorylate the Jun activation domain , JNK1 and JNK2 , required costimulation of T cells with either TPA and Ca2+ ionophore or antibodies to TCR and CD28 .
full activation of the map kinases that phosphorylate the jun activation domain , jnk1 and jnk2 , required costimulation of t cells with either tpa and ca2+ ionophore or antibodies to tcr and cd28 .
O O O O B-protein_family_or_group I-protein_family_or_group O O O B-protein_domain_or_region I-protein_domain_or_region I-protein_domain_or_region O B-protein_molecule O B-protein_molecule O O O O B-cell_type I-cell_type O O B-other_organic_compound O B-atom O O O O B-protein_family_or_group O B-protein_molecule O