Therefore , SR asthma may be due to more than one abnormality , the majority related to a reversible cytokine -induced reduction in GR binding affinity and the second related to an irreversible reduction in GR number .
therefore , sr asthma may be due to more than one abnormality , the majority related to a reversible cytokine -induced reduction in gr binding affinity and the second related to an irreversible reduction in gr number .
O O B-other_name I-other_name O O O O O O O O O O O O O O O B-protein_family_or_group O O O B-protein_family_or_group O O O O O O O O O O O B-protein_family_or_group O O