In transfection experiments , overexpression of wild type IKK1 , a dominant negative mutant IKK1 ( K44M ) , or wild type IKK2 did not affect LPS -induced kappaB -dependent transcription in monocytic cells .
in transfection experiments , overexpression of wild type ikk1 , a dominant negative mutant ikk1 ( k44m ) , or wild type ikk2 did not affect lps -induced kappab -dependent transcription in monocytic cells .
O O O O O O O O B-protein_molecule O O B-protein_molecule I-protein_molecule I-protein_molecule B-protein_molecule O B-protein_molecule O O O B-protein_molecule I-protein_molecule B-protein_molecule O O O B-lipid O B-protein_molecule O O O B-cell_type I-cell_type O