At the same time , we observed a down-regulation of progenitor-specific surface markers and the up-regulation of differentiation markers restricted to the eosinophil and myeloid lineages .
at the same time , we observed a down-regulation of progenitor-specific surface markers and the up-regulation of differentiation markers restricted to the eosinophil and myeloid lineages .
O O O O O O O O B-other_name O B-protein_family_or_group I-protein_family_or_group I-protein_family_or_group O O B-other_name O B-protein_family_or_group I-protein_family_or_group O O O B-cell_type O B-cell_type I-cell_type O