Both sites showed activation by Sp3 ; however , the -70 to -65 region was more responsive to Sp3 than to Sp1 .
both sites showed activation by sp3 ; however , the -70 to -65 region was more responsive to sp3 than to sp1 .
O O O O O B-protein_molecule O O O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O O O O B-protein_molecule O O B-protein_molecule O