By expressing mutant forms of the human protein in this cell line , we have been able to delineate the sequences responsible for both the ligand-induced phosphorylation and the degradation of I kappa B alpha .
by expressing mutant forms of the human protein in this cell line , we have been able to delineate the sequences responsible for both the ligand-induced phosphorylation and the degradation of i kappa b alpha .
O O O O O O O O O O B-cell_line I-cell_line O O O O O O O O O O O O O B-other_name I-other_name O O B-other_name O B-protein_molecule I-protein_molecule I-protein_molecule I-protein_molecule O