We show that IL-6 signaling leads to marked increases in the synthesis and secretion of Ig in clonal human B cell lines and newly isolated polyclonal B lymphocytes in vitro .
we show that il-6 signaling leads to marked increases in the synthesis and secretion of ig in clonal human b cell lines and newly isolated polyclonal b lymphocytes in vitro .
O O O B-protein_molecule O O O O O O O O O O O B-protein_family_or_group O B-cell_line I-cell_line I-cell_line I-cell_line I-cell_line O O B-cell_type I-cell_type I-cell_type I-cell_type O O O