As a step toward elucidating the pathophysiological background of the so-called glucose toxicity to pancreatic beta cells , we induced glycation in HIT-T15 cells using a sugar with strong deoxidizing activity , D-ribose , and examined the effects on insulin gene transcription .
as a step toward elucidating the pathophysiological background of the so-called glucose toxicity to pancreatic beta cells , we induced glycation in hit-t15 cells using a sugar with strong deoxidizing activity , d-ribose , and examined the effects on insulin gene transcription .
O O O O O O B-other_name I-other_name O O O B-carbohydrate O O B-cell_type I-cell_type I-cell_type O O O O O B-cell_type I-cell_type O O O O O O O O B-carbohydrate O O O O O O B-lipid O O O