In contrast , in a number of multiple myeloma cell lines , representing differentiated , plasma cell-like B cells , PU . 1 DNA binding activity , mRNA expression , and Pu box -dependent transactivation were absent or detectable at a very low level .
in contrast , in a number of multiple myeloma cell lines , representing differentiated , plasma cell-like b cells , pu . 1 dna binding activity , mrna expression , and pu box -dependent transactivation were absent or detectable at a very low level .
O O O O O O O B-cell_line I-cell_line I-cell_line I-cell_line O O B-cell_type I-cell_type I-cell_type I-cell_type I-cell_type I-cell_type O B-protein_molecule I-protein_molecule I-protein_molecule O O O O B-other_name I-other_name O O B-DNA_domain_or_region I-DNA_domain_or_region O O O O O O O O O O O O