Because the -180 site is not required for trans-activation , it was possible to confirm by mutation in the normal mouse IL-2 enhancer that this site is absolutely essential for anergy induction .
because the -180 site is not required for trans-activation , it was possible to confirm by mutation in the normal mouse il-2 enhancer that this site is absolutely essential for anergy induction .
O O B-DNA_domain_or_region I-DNA_domain_or_region O O O O B-other_name O O O O O O O O O O O B-DNA_domain_or_region B-protein_molecule O O O O O O O O B-other_name I-other_name O