Ligand binding to the ligand binding domain of these receptors induces conformational changes that are evidenced by an increased resistance of this domain to proteases .
ligand binding to the ligand binding domain of these receptors induces conformational changes that are evidenced by an increased resistance of this domain to proteases .
O O O O B-protein_domain_or_region I-protein_domain_or_region I-protein_domain_or_region O O B-protein_family_or_group O B-other_name I-other_name O O O O O O O O O O O B-protein_family_or_group O