By using 70Z/3-derived pre-B-cell lines either lacking or expressing human CD14 ( the LPS receptor ) , it was observed that expression of human CD14 imparted responsiveness to LPS but not to OspA or spirochetal lipopeptides ( assessed by induction of NF-kappa B and expression of surface immunoglobulin M ) .
by using 70z/3-derived pre-b-cell lines either lacking or expressing human cd14 ( the lps receptor ) , it was observed that expression of human cd14 imparted responsiveness to lps but not to ospa or spirochetal lipopeptides ( assessed by induction of nf-kappa b and expression of surface immunoglobulin m ) .
O O B-cell_line I-cell_line I-cell_line O O O O B-protein_molecule I-protein_molecule O O B-lipid O O O O O O O O O B-protein_molecule I-protein_molecule O O O B-lipid O O O B-protein_molecule O B-protein_family_or_group I-protein_family_or_group O O O O O B-protein_complex I-protein_complex O O O B-protein_molecule I-protein_molecule I-protein_molecule O O