Defensin resistance is not the only virulence characteristic controlled by the PhoP -PhoQ regulon because mutations in pagC , as well as ones in the phoP locus that resulted in constitutive pag activation ( phenotype PhoPc ) , had no effect on defensin resistance , even though they rendered the organism avirulent and deficient in survival within macrophages .
defensin resistance is not the only virulence characteristic controlled by the phop -phoq regulon because mutations in pagc , as well as ones in the phop locus that resulted in constitutive pag activation ( phenotype phopc ) , had no effect on defensin resistance , even though they rendered the organism avirulent and deficient in survival within macrophages .
B-other_name I-other_name O O O O B-other_name I-other_name O O O B-protein_molecule B-protein_molecule O O B-other_name O B-DNA_domain_or_region O O O O O O O B-DNA_domain_or_region O O O O B-other_name B-DNA_family_or_group O O O B-protein_molecule O O O O O O B-protein_family_or_group O O O O O O O O O O O O O O B-cell_type O