In addition , it has been established that tumor necrosis factor-alpha ( TNF-alpha ) can activate the expression of wild type p53 in concert with the nuclear transcription factor , NF-kappa B .
in addition , it has been established that tumor necrosis factor-alpha ( tnf-alpha ) can activate the expression of wild type p53 in concert with the nuclear transcription factor , nf-kappa b .
O O O O O O O O B-protein_molecule I-protein_molecule I-protein_molecule O B-protein_molecule O O O O O O B-protein_molecule I-protein_molecule I-protein_molecule O O O O B-protein_family_or_group I-protein_family_or_group I-protein_family_or_group O B-protein_complex I-protein_complex O