However , Nef does not affect the DNA-binding activity of other transcription factors implicated in HIV-1 regulation , including SP-1 , USF , URS , and NF-AT .
however , nef does not affect the dna-binding activity of other transcription factors implicated in hiv-1 regulation , including sp-1 , usf , urs , and nf-at .
O O B-protein_molecule O O O O O O O O B-protein_family_or_group I-protein_family_or_group O O B-virus O O O B-protein_molecule O B-protein_molecule O B-protein_molecule O O B-protein_molecule O