In addition , the transcription factor Stat-3 was tyrosine phosphorylated in the cytoplasm and subsequently translocated to the cell nucleus .
in addition , the transcription factor stat-3 was tyrosine phosphorylated in the cytoplasm and subsequently translocated to the cell nucleus .
O O O O B-protein_family_or_group I-protein_family_or_group B-protein_molecule O O O O O B-cell_component O O O O O B-cell_component I-cell_component O