To test whether disordered memory T cell differentiation contributes to the typical Th1-dominated chronic inflammation in RA we investigated differentiation of resting CD4+ memory T cells in patients with early ( 6 wk to 12 mo ) untreated RA and in age- and sex-matched healthy controls in vitro .
to test whether disordered memory t cell differentiation contributes to the typical th1-dominated chronic inflammation in ra we investigated differentiation of resting cd4+ memory t cells in patients with early ( 6 wk to 12 mo ) untreated ra and in age- and sex-matched healthy controls in vitro .
O O O O B-cell_type I-cell_type I-cell_type O O O O O O O O O B-other_name O O O O B-cell_type I-cell_type I-cell_type I-cell_type I-cell_type O B-multi_cell O O O O O O O O O O B-other_name O O O O B-multi_cell I-multi_cell I-multi_cell O O O