Pretreatment of PBMCs with pertussis toxin blocked the functions of C3a and C3a ( desArg ) , indicating that the actions of these two molecules are mediated by a G protein -coupled pathway .
pretreatment of pbmcs with pertussis toxin blocked the functions of c3a and c3a ( desarg ) , indicating that the actions of these two molecules are mediated by a g protein -coupled pathway .
O O B-cell_type O B-protein_molecule I-protein_molecule O O O O B-protein_molecule O B-protein_molecule I-protein_molecule I-protein_molecule I-protein_molecule O O O O O O O O O O O O O B-protein_family_or_group I-protein_family_or_group O O O