The E2A-HLF fusion gene , generated by t ( 17 ; 19 ) ( q22 ; p13 ) in acute lymphoblastic leukemia ( ALL ) , encodes a chimeric transcription factor in which the trans-activating domains of E2A are fused to the DNA- binding and dimerization domains of hepatic leukemic factor ( HLF ) .
the e2a-hlf fusion gene , generated by t ( 17 ; 19 ) ( q22 ; p13 ) in acute lymphoblastic leukemia ( all ) , encodes a chimeric transcription factor in which the trans-activating domains of e2a are fused to the dna- binding and dimerization domains of hepatic leukemic factor ( hlf ) .
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