First , a substantial number of cells can express class II molecules in the absence of CIITA , albeit at 5-fold reduced levels , most notably dendritic cells in s . c . lymph nodes ; therefore , the CIITA gene cannot be an absolute ' master gene ' controlling the expression of class II molecules , as had been thought .
first , a substantial number of cells can express class ii molecules in the absence of ciita , albeit at 5-fold reduced levels , most notably dendritic cells in s . c . lymph nodes ; therefore , the ciita gene cannot be an absolute ' master gene ' controlling the expression of class ii molecules , as had been thought .
O O O O O O O O O B-protein_family_or_group I-protein_family_or_group I-protein_family_or_group O O O O B-protein_molecule O O O O O O O O O B-cell_type I-cell_type O O O O O O O O O O O B-protein_molecule O O O O O O B-DNA_domain_or_region I-DNA_domain_or_region O O O O O B-protein_family_or_group I-protein_family_or_group I-protein_family_or_group O O O O O O