DESIGN : Eighteen hirsute patients with regular menses were studied basally and during treatment with 125 mg flutamide , three times per day for 12 months .
design : eighteen hirsute patients with regular menses were studied basally and during treatment with 125 mg flutamide , three times per day for 12 months .
O O O B-multi_cell B-multi_cell O O O O O O O O O O O O B-other_organic_compound O O O O O O O O O