Costimulatory signals , such as activation of the CD28 cell surface molecule on T cells , lead to activation through a distinct region of the granulocyte-macrophage colony-stimulating factor ( GM-CSF ) promoter .
costimulatory signals , such as activation of the cd28 cell surface molecule on t cells , lead to activation through a distinct region of the granulocyte-macrophage colony-stimulating factor ( gm-csf ) promoter .
O O O O O O O O B-protein_molecule I-protein_molecule I-protein_molecule I-protein_molecule O B-cell_type I-cell_type O O O O O O O O O O B-protein_molecule I-protein_molecule I-protein_molecule O B-protein_molecule O O O