Although the stimulation of T cells from young subjects resulted in coordinated increases of nuclear protein complexes binding the AP-1 TRE , c-jun TRE , and c-fos SRE DNA sequence motifs , age-related reductions in the activation of AP-1 were accompanied by decreased levels of c-jun TRE and c-fos SRE binding complexes .
although the stimulation of t cells from young subjects resulted in coordinated increases of nuclear protein complexes binding the ap-1 tre , c-jun tre , and c-fos sre dna sequence motifs , age-related reductions in the activation of ap-1 were accompanied by decreased levels of c-jun tre and c-fos sre binding complexes .
O O O O B-cell_type I-cell_type O B-multi_cell I-multi_cell O O O O O B-protein_complex I-protein_complex I-protein_complex O O B-protein_molecule O O B-DNA_domain_or_region I-DNA_domain_or_region O O B-DNA_domain_or_region B-DNA_domain_or_region O O O O O O O O O O B-protein_molecule O O O O O O B-(AND protein_complex protein_complex) I-(AND protein_complex protein_complex) I-(AND protein_complex protein_complex) I-(AND protein_complex protein_complex) I-(AND protein_complex protein_complex) I-(AND protein_complex protein_complex) I-(AND protein_complex protein_complex) O