We overexpressed AML1a ( without the transcription-activating domain ) and AML1b ( with the domain ) proteins in K562 leukemia cells , which can be induced to differentiate into hemoglobin-producing cells and megakaryocytes .
we overexpressed aml1a ( without the transcription-activating domain ) and aml1b ( with the domain ) proteins in k562 leukemia cells , which can be induced to differentiate into hemoglobin-producing cells and megakaryocytes .
O O B-protein_molecule O O O B-protein_domain_or_region I-protein_domain_or_region O O B-protein_molecule O O O O O O O B-cell_type I-cell_type I-cell_type O O O O O O O O B-cell_type I-cell_type O B-cell_type O