To understand the mechanism of leukemic cell infiltration into organs , we studied the expression and regulation of L-selectin mRNA in fresh leukemic cells of adult T-cell leukemia ( ATL ) patients and investigated the response of the L-selectin promoter to human T-cell lymphotropic virus type 1 ( HTLV-1 ) Tax , which is a viral transcriptional transactivator .
to understand the mechanism of leukemic cell infiltration into organs , we studied the expression and regulation of l-selectin mrna in fresh leukemic cells of adult t-cell leukemia ( atl ) patients and investigated the response of the l-selectin promoter to human t-cell lymphotropic virus type 1 ( htlv-1 ) tax , which is a viral transcriptional transactivator .
O O O O O B-cell_type I-cell_type O O B-body_part O O O O O O O O B-protein_molecule O O O B-cell_type I-cell_type O B-other_name I-other_name I-other_name O B-other_name O O O O O O O O B-protein_molecule O O B-virus I-virus I-virus I-virus I-virus I-virus O B-virus O O O O O O B-protein_family_or_group I-protein_family_or_group I-protein_family_or_group O