Paradoxically , removal of interdomain B ( to create the construct designated Delta ) , containing the Y292 , Y315 , and Y319 sites , did not eliminate the ability of ZAP-70 to induce multiple gene reporters in Syk-deficient DT-40 B cells and ZAP-70 /Syk-deficient Jurkat cells .
paradoxically , removal of interdomain b ( to create the construct designated delta ) , containing the y292 , y315 , and y319 sites , did not eliminate the ability of zap-70 to induce multiple gene reporters in syk-deficient dt-40 b cells and zap-70 /syk-deficient jurkat cells .
O O O O B-protein_domain_or_region I-protein_domain_or_region O O O O O O B-protein_molecule O O O O B-amino_acid_monomer O B-amino_acid_monomer O O B-amino_acid_monomer O O O O O O O O B-protein_molecule O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O B-cell_line I-cell_line I-cell_line I-cell_line O B-protein_molecule O O O O