Examination of IkappaB alpha regulation revealed that TNF-alpha -mediated degradation of IkappaB alpha in both memory and naive T cells from the elderly was severely impaired , thus contributing to the lowered induction of the observed NFkappaB .
examination of ikappab alpha regulation revealed that tnf-alpha -mediated degradation of ikappab alpha in both memory and naive t cells from the elderly was severely impaired , thus contributing to the lowered induction of the observed nfkappab .
O O B-protein_molecule I-protein_molecule O O O B-protein_molecule O O O B-protein_molecule I-protein_molecule O O O O O O O O O O O O O O O O O O O O O O O B-protein_complex O