Because binding sites for B-cell-specific activator protein ( BSAP ) are located upstream of several switch regions in the immunoglobulin heavy chain gene cluster , BSAP might play a role in the regulation of germline transcription and isotype switching .
because binding sites for b-cell-specific activator protein ( bsap ) are located upstream of several switch regions in the immunoglobulin heavy chain gene cluster , bsap might play a role in the regulation of germline transcription and isotype switching .
O B-DNA_domain_or_region I-DNA_domain_or_region O B-protein_molecule I-protein_molecule I-protein_molecule O B-protein_molecule O O O O O O O O O O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O B-protein_molecule O O O O O O O O B-DNA_domain_or_region O O B-other_name I-other_name O