Using human T lymphocytes and T cell lines , we show that progesterone , at concentrations found in the placenta , rapidly and reversibly blocks voltage-gated and calcium-activated K+ channels ( KV and KCa , respectively ) , resulting in depolarization of the membrane potential .
using human t lymphocytes and t cell lines , we show that progesterone , at concentrations found in the placenta , rapidly and reversibly blocks voltage-gated and calcium-activated k+ channels ( kv and kca , respectively ) , resulting in depolarization of the membrane potential .
O B-cell_type B-cell_type I-cell_type O B-cell_line I-cell_line I-cell_line O O O O B-lipid O O O O O O O O O O O O O O O O O O B-protein_family_or_group O B-protein_family_or_group O O O O O O O O O B-other_name I-other_name O