We demonstrate the utility of using primary lymphocyte models to study HTLV-I transcription in the context of cell signaling and suggest that activated PBMC maintain elevated levels of P-CREB , which promote basal HTLV-I transcription and enhance viral persistence in vivo .
we demonstrate the utility of using primary lymphocyte models to study htlv-i transcription in the context of cell signaling and suggest that activated pbmc maintain elevated levels of p-creb , which promote basal htlv-i transcription and enhance viral persistence in vivo .
O O O O O O B-other_name I-other_name I-other_name O O B-virus O O O O O O O O O O O B-cell_type O O O O B-protein_molecule O O O O B-virus O O O B-other_name I-other_name O O O