Expression of full-length and mutant cDNA clones in bacteria reveal that the single HMG motif , which is predicted to contain two extended alpha-helical segments , is sufficient to direct the sequence-specific binding of TCF-1 alpha to DNA .
expression of full-length and mutant cdna clones in bacteria reveal that the single hmg motif , which is predicted to contain two extended alpha-helical segments , is sufficient to direct the sequence-specific binding of tcf-1 alpha to dna .
O O B-DNA_family_or_group O B-DNA_family_or_group I-DNA_family_or_group I-DNA_family_or_group O O O O O B-protein_substructure I-protein_substructure I-protein_substructure O O O O O O O O B-protein_domain_or_region I-protein_domain_or_region O O O O O O O O O B-protein_molecule I-protein_molecule O B-DNA_N/A O