In the present work , we investigated the molecular events leading to NF-kappa B activation by TNF alpha in a human T cell line ( Jurkat ) and its subclone JCT6 , which presents a deficiency in the PKA transduction pathway .
in the present work , we investigated the molecular events leading to nf-kappa b activation by tnf alpha in a human t cell line ( jurkat ) and its subclone jct6 , which presents a deficiency in the pka transduction pathway .
O O O O O O O O O O O O B-protein_molecule I-protein_molecule O O B-protein_molecule I-protein_molecule O O B-cell_line I-cell_line I-cell_line I-cell_line O B-cell_line O O O O B-cell_line O O O O O O O B-protein_molecule O O O