Site-directed mutagenesis demonstrated that this HS-40 enhancer- zeta 2 globin promoter interaction is mediated by the two GATA-1 factor binding motifs located at -230 and -104 , respectively .
site-directed mutagenesis demonstrated that this hs-40 enhancer- zeta 2 globin promoter interaction is mediated by the two gata-1 factor binding motifs located at -230 and -104 , respectively .
O O O O O B-DNA_domain_or_region O B-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region I-DNA_domain_or_region O O O O O O B-DNA_substructure I-DNA_substructure I-DNA_substructure I-DNA_substructure O O O O O O O O