The data suggest that CD4+ memory T cells from patients with early untreated RA manifest an intrinsic abnormality in their ability to differentiate into specific cytokine-producing effector cells that might contribute to the characteristic Th1-dominated chronic ( auto ) immune inflammation in RA .
the data suggest that cd4+ memory t cells from patients with early untreated ra manifest an intrinsic abnormality in their ability to differentiate into specific cytokine-producing effector cells that might contribute to the characteristic th1-dominated chronic ( auto ) immune inflammation in ra .
O O O O B-cell_type I-cell_type I-cell_type I-cell_type O B-multi_cell O O O B-other_name O O B-other_name I-other_name O O O O O O O B-cell_type I-cell_type I-cell_type O O O O O O B-other_name I-other_name I-other_name I-other_name I-other_name I-other_name I-other_name O B-other_name O