tokens: In this study we demonstrated that a mutant Escherichia coli endotoxin lacking myristoyl fatty acid at the 3' R-3-hydroxymyristate position of the lipid A moiety retained its full capacity to coagulate Limulus amoebocyte lysate compared with the wild-type E . coli endotoxin and markedly stimulated the activation of human monocyte nuclear factor-kappaB and the induction of Mn SOD mRNA and enzyme activity .
folded_tokens: in this study we demonstrated that a mutant escherichia coli endotoxin lacking myristoyl fatty acid at the 3' r-3-hydroxymyristate position of the lipid a moiety retained its full capacity to coagulate limulus amoebocyte lysate compared with the wild-type e . coli endotoxin and markedly stimulated the activation of human monocyte nuclear factor-kappab and the induction of mn sod mrna and enzyme activity .
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